List of all Reactions
A four digit code that defines the overall chemical transformation performed by the enzyme.
The domain that is responsible for the function of the enzyme.
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Reactions in SFLD
# | Reaction Name | Reaction Type | EC Number | KEGG R Number | Rhea ID | Directionality | Substrates | Products | Schemes | Functional Domains |
---|---|---|---|---|---|---|---|---|---|---|
1 | o-succinylbenzoate synthase | cognate | 4.2.1.113 | R04031 | 10199 | reversible | 1 | 2 | 1 | 1 |
2 | methylaspartate ammonia-lyase | cognate | 4.3.1.2 | R03696 | 12832 | reversible | 1 | 2 | 1 | 1 |
3 | gluconate dehydratase | cognate | 4.2.1.39 | R01538 | 21615 | reversible | 1 | 2 | 1 | 1 |
4 | glucarate dehydratase | cognate | 4.2.1.40 | R02752 | 14576 | reversible | 1 | 2 | 1 | 2 |
5 | L-rhamnonate dehydratase | cognate | 4.2.1.90 | R03774 | 23083 | reversible | 1 | 2 | 1 | 2 |
6 | galactonate dehydratase | cognate | 4.2.1.6 | R03033 | 18652 | reversible | 1 | 2 | 1 | 1 |
7 | mandelate racemase | cognate | 5.1.2.2 | R03791 | 13948 | reversible | 1 | 1 | 1 | 1 |
8 | mannonate dehydratase | cognate | 4.2.1.8 | R05606 | 20100 | reversible | 1 | 2 | 2 | 3 |
9 | phosphopyruvate hydratase | cognate | 4.2.1.11 | R00658 | 10167 | reversible | 1 | 2 | 1 | 1 |
10 | 3-chloromuconate cycloisomerase (non-dehalogenating) | cognate | 5.5.1.7 | R04259 | 11035 | reversible | 1 | 2 | 1 | 2 |
11 | muconate cycloisomerase | cognate | 5.5.1.1 | R06989 | 10643 | reversible | 2 | 1 | 2 | 13 |
12 | L-Ala-D/L-Glu epimerase | cognate | 5.1.1.20 | 28397 | reversible | 1 | 1 | 1 | 1 | |
13 | N-acylamino acid racemase | cognate | 5.1.1.- | reversible | 1 | 1 | 1 | 1 | ||
28 | acireductone synthase | cognate | R07395 | 21703 | reversible | 2 | 2 | 1 | 1 | |
31 | 2-deoxyglucose-6-phosphatase | cognate | R02587 | 22239 | reversible | 2 | 2 | 1 | 4 | |
32 | cis-3-Hydroxy-L-proline dehydratase | cognate | 4.2.1.- | forward | 1 | 2 | 1 | 3 | ||
35 | glycerol-1-phosphatase | cognate | R07298 | 11479 | reversible | 2 | 2 | 1 | 8 | |
38 | mannosyl-3-phosphoglycerate phosphatase | cognate | R05790 | 19312 | reversible | 2 | 2 | 1 | 1 | |
39 | lipid-phosphate phosphatase | cognate | R07582 | 16540 | reversible | 2 | 2 | 1 | 1 | |
41 | (S)-2-haloacid dehalogenase (configuration-inverting) | generic | 3.8.1.2 | R03830 | reversible | 2 | 2 | 1 | 5 | |
42 | beta-phosphoglucomutase | cognate | 5.4.2.6 | R02728 | 20116 | reversible | 1 | 1 | 1 | 1 |
43 | histidinol-phosphatase | cognate | R03013 | 14468 | reversible | 2 | 2 | 1 | 1 | |
44 | biotin synthase | cognate | R01078 | 22063 | reversible | 4 | 5 | 1 | 1 | |
45 | methylornithine synthase | cognate | 32762 | reversible | 1 | 1 | 1 | 1 | ||
46 | 2-iminoacetate synthase | cognate | R10246 | 26364 | reversible | 3 | 5 | 1 | 1 | |
47 | 3-methyl-2-indolic acid synthase | cognate | reversible | 2 | 4 | 1 | 2 | |||
48 | HydG | cognate | reversible | 3 | 5 | 1 | 2 | |||
51 | polynucleotide 5'-hydroxyl-kinase | generic | R03840 | reversible | 2 | 2 | 1 | 1 | ||
53 | haloacetate dehalogenase | generic | R02336 | reversible | 2 | 3 | 1 | 1 | ||
57 | 3-deoxy-manno-octulosonate-8-phosphatase | cognate | R03350 | 11503 | reversible | 2 | 2 | 1 | 6 | |
87 | xylonate dehydratase | cognate | 4.2.1.82 | R02429 | 19160 | unknown | 1 | 2 | 1 | 2 |
134 | L-fuconate dehydratase | cognate | 4.2.1.68 | R03688 | 22775 | reversible | 1 | 2 | 1 | |
140 | D(-)-tartrate dehydratase | cognate | 4.2.1.81 | R00340 | 18292 | reversible | 1 | 2 | 1 | |
148 | galactarate dehydratase | cognate | 4.2.1.42 | R05608 | 16008 | reversible | 1 | 2 | 1 | |
149 | L-talarate dehydratase | cognate | 4.2.1.156 | 44028 | reversible | 1 | 2 | 1 | ||
150 | L-talarate epimerase | cognate | 5.1.-.- | reversible | 1 | 1 | 1 | |||
170 | arabinonate dehydratase | cognate | 4.2.1.5 | R03032 | 21839 | reversible | 1 | 2 | 1 | |
201 | L-galactonate dehydratase | cognate | 4.2.1.146 | 38106 | reversible | 1 | 2 | 1 | ||
202 | lipoyl synthase | cognate | 2.8.1.8 | R07767 | 16588 | reversible | 4 | 5 | 1 | 1 |
203 | 23S rRNA (adenine2503-C2)-methyltransferase | cognate | 2.1.1.192 | 42919 | reversible | 3 | 5 | 1 | 1 | |
204 | coproporphyrinogen dehydrogenase | cognate | 1.3.99.22 | R06895 | 15428 | reversible | 2 | 4 | 1 | 6 |
205 | tRNA 4-demethylwyosine synthase (AdoMet-dependent) | cognate | 4.1.3.44 | R10552 | 36350 | reversible | 3 | 5 | 1 | 1 |
206 | Ser-type sulfatase maturase | cognate | 1.1.99.- | reversible | 2 | 3 | 1 | 1 | ||
207 | Cys-type sulfatase maturase | cognate | 1.1.99.- | reversible | 3 | 4 | 1 | 1 | ||
208 | Tyr-Glu cyclase | cognate | 5.-.-.- | reversible | 2 | 4 | 1 | 1 | ||
209 | lysine 2,3-aminomutase | cognate | 5.4.3.2 | R00461 | 19180 | reversible | 1 | 1 | 2 | 2 |
210 | glutamate 2,3-aminomutase | cognate | 5.4.3.9 | 34242 | reversible | 1 | 1 | 1 | 1 | |
211 | arginine 2,3-aminomutase | cognate | 5.4.3.- | reversible | 1 | 1 | 1 | 1 | ||
212 | spore photoproduct lyase | cognate | 4.1.99.14 | reversible | 1 | 1 | 2 | 2 | ||
213 | CofH | cognate | 2.5.1.- | reversible | 3 | 4 | 1 | 1 | ||
214 | CofG | cognate | 5.-.-.- | reversible | 2 | 3 | 1 | 2 | ||
215 | [ribosomal protein S12] (aspartate89-C3)-methylthiotransferase | cognate | 2.8.4.4 | 37090 | R10652 | reversible | 3 | 4 | 1 | 1 |
216 | tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase | cognate | 2.8.4.5 | R10649 | reversible | 3 | 4 | 1 | 1 | |
217 | tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase | cognate | 2.8.4.3 | R10645 | 37070 | reversible | 4 | 7 | 1 | 1 |
218 | 23S rRNA (adenine2503-C8)-methyltransferase | cognate | 2.1.1.224 | 42635 | reversible | 3 | 5 | 1 | 1 | |
219 | [formate-C-acetyltransferase]-activating enzyme | cognate | 1.97.1.4 | R04710 | reversible | 3 | 4 | 1 | 1 | |
221 | 7-carboxy-7-deazaguanine synthase | cognate | 4.3.99.3 | 27977 | reversible | 2 | 2 | 2 | 2 | |
222 | [4-hydroxyphenylacetate decarboxylase]-activating enzyme | cognate | 1.97.1.- | reversible | 3 | 4 | 1 | 1 | ||
223 | cyclic pyranopterin phosphate synthase | cognate | 4.1.99.18 | 26380 | reversible | 1 | 2 | 1 | 1 | |
225 | cyclic dehypoxanthinyl futalosine synthase | cognate | 1.21.98.1 | 33086 | reversible | 2 | 4 | 1 | 1 | |
231 | anaerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase | cognate | 1.14.13.- | reversible | 3 | 3 | 1 | 1 | ||
232 | avilamycin A epimerase | cognate | 5.1.3.- | reversible | 2 | 3 | 1 | 1 | ||
236 | L-lyxonate dehydratase | cognate | 4.2.1.- | unknown | 1 | 2 | 1 | 4 | ||
238 | nosiheptide methyltransferase | cognate | 2.1.1.- | reversible | 2 | 4 | 1 | 1 | ||
241 | 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) | cognate | 1.1.99.38 | 34278 | reversible | 2 | 4 | 1 | 1 | |
242 | UDP-N-acetyl-tunicamine-uracil synthase | cognate | 4.-.-.- | reversible | 2 | 1 | 1 | 1 | ||
243 | oxsB | cognate | 5.-.-.- | reversible | 1 | 1 | 1 | 1 | ||
244 | dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase | cognate | 4.3.1.30 | 39650 | reversible | 3 | 6 | 1 | 1 | |
261 | hop-22(29)-ene C2-methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
262 | galactarate dehydratase 2/3 | cognate | 4.2.1.- | forward | 1 | 2 | 2 | 4 | ||
263 | galactarolactone cycloisomerase | cognate | 5.5.1.- | unknown | 1 | 1 | 1 | 1 | ||
264 | bacteriochlorophyll C8 methyltransferase | generic | reversible | 2 | 4 | 1 | 1 | |||
265 | bacteriochlorophyll C12 methyltransferase | generic | reversible | 2 | 4 | 1 | 1 | |||
266 | P-methyltransferase | cognate | 2.1.1.- | reversible | 2 | 4 | 1 | 1 | ||
267 | thioether cross-link between Cys and Asp | cognate | forward | 2 | 1 | 1 | 1 | |||
268 | adenosyl-hopene transferase | cognate | 2.5.1.- | reversible | 2 | 3 | 1 | 2 | ||
270 | gentamicin N-methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
272 | TDP-rhammose dehydrogenase | cognate | reversible | 2 | 4 | 1 | 1 | |||
273 | fortimicin KL1 methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
274 | gentamicin C6 methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
275 | aminobacteriohopanepentol C3-methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
276 | aminobacteriohopanetetrol C3-methyltransferase | cognate | 2.1.1.- | reversible | 2 | 4 | 1 | 1 | ||
277 | 3-methyl-2-indolic acid methyltransferase | cognate | reversible | 2 | 4 | 1 | 2 | |||
281 | [glycerol dehydratase]-activating enzyme | cognate | reversible | 3 | 4 | 1 | 1 | |||
282 | [benzylsuccinate synthase]-activating enzyme | cognate | reversible | 3 | 4 | 1 | 1 | |||
283 | [anaerobic ribonucleoside-triphosphate reductase]-activating protein | cognate | reversible | 3 | 4 | 1 | 1 | |||
284 | valine cyclopropanase | cognate | reversible | 2 | 3 | 1 | 1 | |||
294 | tryptophan 2-C-methyltransferase | cognate | R00683 | 17324 | reversible | 2 | 4 | 1 | 1 | |
295 | yatakemycin methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
367 | aminodeoxyfutalosine synthase | cognate | 33078 | reversible | 3 | 4 | 1 | 1 | ||
371 | 2,4-dichloromuconate cycloisomerase | cognate | 5.5.1.11 | R05393 | unknown | 1 | 2 | 1 | 1 | |
372 | 2-chloromuconate cycloisomerase (dehalogenating) | cognate | 5.5.1.- | unknown | 1 | 2 | 1 | 4 | ||
373 | 3-methylmuconate cycloisomerase | cognate | 5.5.1.- | unknown | 1 | 1 | 1 | 2 | ||
374 | 3-chloromuconate cycloisomerase (dehalogenating, to protoanemonin) | cognate | 5.5.1.- | forward | 1 | 3 | 1 | 1 | ||
375 | 3-chloromuconate cycloisomerase (dehalogenating, to dienelactone) | cognate | 5.5.1.- | forward | 1 | 2 | 1 | 1 | ||
377 | 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase | cognate | 3.1.3.87 | reversible | 2 | 2 | 1 | 1 | ||
378 | 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase | cognate | 3.1.3.- | reversible | 2 | 2 | 1 | 5 | ||
379 | glucose-1-phosphatase | cognate | 3.1.3.10 | reversible | 2 | 2 | 1 | 2 | ||
380 | FMN phosphatase | cognate | 3.1.3.2 | reversible | 2 | 2 | 1 | 2 | ||
381 | D-glycero-D-manno-heptose-1,7-bisphosphate 7-phosphatase | cognate | 3.1.3.- | reversible | 2 | 2 | 1 | 11 | ||
383 | HMP-PP phosphatase | unknown | 3.1.3.- | unknown | 2 | 2 | 1 | 3 | ||
384 | kanosamine-6-phosphate phosphatase | cognate | 3.1.3.92 | reversible | 2 | 2 | 1 | 3 | ||
385 | mannosylfructose-phosphate phosphatase | cognate | 3.1.3.79 | reversible | 2 | 2 | 1 | 1 | ||
386 | N-acylneuraminate-9-phosphatase | cognate | 3.1.3.29 | reversible | 2 | 2 | 1 | 3 | ||
387 | C-terminal tyrosine decarboxylase | cognate | reversible | 1 | 2 | 1 | 1 | |||
388 | cytosylglucuronate decarboxylase | cognate | reversible | 2 | 4 | 1 | 1 | |||
389 | bacteriohopanetetrol cyclitol ether synthase | cognate | reversible | 2 | 3 | 1 | 1 | |||
390 | trans-but-2-enoyl-[ACP] cycloisomerase | cognate | reversible | 2 | 3 | 1 | 1 | |||
391 | didecarboxysirohaem deacetylase | cognate | reversible | 2 | 4 | 1 | 1 | |||
392 | Fe-coproporphyrin III decarboxylase | cognate | reversible | 2 | 4 | 1 | 1 | |||
393 | neomycin C epimerase | cognate | R08904 | reversible | 2 | 3 | 1 | 1 | ||
394 | thioether cross-link between Cys and Thr | cognate | reversible | 3 | 3 | 4 | 4 | |||
395 | thioether cross-link between Cys and Phe | cognate | reversible | 3 | 3 | 1 | 1 | |||
396 | carbapenem intermediate methyltransferase, second methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
397 | carbapenem intermediate methyltransferase, first methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
398 | thioether cross-link between Cys and Glu | cognate | forward | 3 | 3 | 1 | 1 | |||
399 | thioether cross-link between Cys and Met | cognate | reversible | 3 | 3 | 1 | 1 | |||
400 | thioether cross-link between Cys and Ser | cognate | forward | 3 | 3 | 2 | 2 | |||
401 | thioether cross-link between Cys and Ala | cognate | forward | 3 | 3 | 1 | 1 | |||
402 | thioether cross-link between Cys and Asn | cognate | forward | 3 | 3 | 1 | 1 | |||
403 | thioether cross-link between Cys and Tyr | cognate | forward | 3 | 3 | 1 | 1 | |||
404 | Methylation of tallysomycin | cognate | reversible | 2 | 4 | 1 | 1 | |||
405 | methylation of bleomycin | cognate | reversible | 2 | 4 | 1 | 1 | |||
407 | paromamine deoxygenase | cognate | reversible | 2 | 4 | 1 | 1 | |||
408 | clorobiocin pyrrole-2-carboxy methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
409 | chondrochloren A methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
410 | phosphonoacetaldehyde methylase | cognate | reversible | 2 | 4 | 1 | 1 | |||
411 | 7,8-dihydro-6-hydroxymethylpterin dimethyltransferase | cognate | reversible | 4 | 5 | 1 | 1 | |||
412 | hopan-22-ol 2-methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
413 | tetrahymanol 2-methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
414 | hop-21-ene 2-methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
415 | hop-17(21)-ene 2-methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
416 | bacteriohopanetetrol 2-methyltransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
418 | thioacetal methlytransferase | cognate | reversible | 2 | 4 | 1 | 1 | |||
430 | EP-UMP cyclase | cognate | reversible | 2 | 3 | 1 | 2 | |||
431 | 3,6-anhydro-alpha-L-galactonate cycloisomerase | cognate | 5.5.1.25 | R10900 | unknown | 1 | 1 | 1 | ||
432 | 4R-hydroxyproline betaine 2-epimerase | cognate | 5.1.1.22 | R11630 | reversible | 1 | 1 | 1 | ||
433 | N-succinylamino acid racemase | cognate | reversible | 1 | 1 | 2 |