Reaction: [benzylsuccinate synthase]-activating enzyme List of reactions
| Reaction name: | [benzylsuccinate synthase]-activating enzyme | Reaction type: | cognate | ||
|---|---|---|---|---|---|
| EC number: | Kegg ID: | Rhea ID: | |||
| Directionality: | reversible | Curation status: | valid | Classification: | public |
| Description: | A single glycine residue in EC 4.1.99.11, benzylsuccinate synthase, is oxidized to the corresponding radical by transfer of H from its CH2 to S-adenosyl-L-methionine (AdoMet) with concomitant cleavage of the latter. | ||||
| Curator notes: | The identity of the other species that accepts one of the electrons from the reaction is not clear. | ||||
Substrate
| ID Type | Compound ID | Name | Stoichiometry | Curator notes |
|---|---|---|---|---|
| pdb | 4pkf | benzylsuccinate synthase (inactive) | 1 | |
| chebi | 67040 | S-adenosyl-L-methioninate | 1 | |
| chebi | 62787 | 1,5-dihydroflavin | 1 |
Product
| ID Type | Compound ID | Name | Stoichiometry | Curator notes |
|---|---|---|---|---|
| pdb | 4pkf | benzylsuccinate synthase (active) | 1 | |
| chebi | 57844 | L-methionine zwitterion | 1 | |
| chebi | 17319 | 5'-deoxyadenosine | 1 | |
| chebi | 15817 | semiquinone | 1 |
Schemes
| # | Name |
|---|---|
| 123 | [benzylsuccinate synthase]-activating enzyme, radical SAM superfamily |
Reaction
[benzylsuccinate synthase]-activating enzyme
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| benzylsuccinate synthase (inactive) 4pkf |
S-adenosyl-L-methioninate 67040 |
1,5-dihydroflavin 62787 |
benzylsuccinate synthase (active) 4pkf |
L-methionine zwitterion 57844 |
5'-deoxyadenosine 17319 |
semiquinone 15817 |
EC: | IntEnz: | Kegg: | BioCyc: | BRENDA: |