Reaction: [glycerol dehydratase]-activating enzyme List of reactions
| Reaction name: | [glycerol dehydratase]-activating enzyme | Reaction type: | cognate | ||
|---|---|---|---|---|---|
| EC number: | Kegg ID: | Rhea ID: | |||
| Directionality: | reversible | Curation status: | valid | Classification: | public |
| Description: | A single glycine residue in EC 4.2.1.30, B12-independent glycerol dehydratase, is oxidized to the corresponding radical by transfer of H from its CH2 to S-adenosyl-L-methionine (AdoMet) with concomitant cleavage of the latter. | ||||
| Curator notes: | The identity of the other species that accepts one of the electrons from the reaction is not clear. | ||||
Substrate
| ID Type | Compound ID | Name | Stoichiometry | Curator notes |
|---|---|---|---|---|
| pdb | 1r8w | glycerol dehydratase (inactive) | 1 | Specifically, the Gly residue that is to become an activated glycyl radical. |
| chebi | 67040 | S-adenosyl-L-methioninate | 1 | |
| chebi | 62787 | 1,5-dihydroflavin | 1 |
Product
| ID Type | Compound ID | Name | Stoichiometry | Curator notes |
|---|---|---|---|---|
| pdb | 1r8w | glycerol dehydratase (active) | 1 | |
| chebi | 57844 | L-methionine zwitterion | 1 | |
| chebi | 17319 | 5'-deoxyadenosine | 1 | |
| chebi | 15817 | semiquinone | 1 |
Schemes
| # | Name |
|---|---|
| 122 | [glycerol dehydratase]-activating enzyme, radical SAM superfamily |
Reaction
[glycerol dehydratase]-activating enzyme
 |
+ |  |
+ |  |
 |
|
+ |  |
+ |  |
+ |  |
||
| glycerol dehydratase (inactive) 1r8w |
S-adenosyl-L-methioninate 67040 |
1,5-dihydroflavin 62787 |
glycerol dehydratase (active) 1r8w |
L-methionine zwitterion 57844 |
5'-deoxyadenosine 17319 |
semiquinone 15817 |
EC: | IntEnz: | Kegg: | BioCyc: | BRENDA: |