Reaction: beta-phosphoglucomutase List of reactions
Reaction name: | beta-phosphoglucomutase | Reaction type: | cognate | ||
---|---|---|---|---|---|
EC number: | 5.4.2.6 | Kegg ID: | R02728 | Rhea ID: | 20116 |
Directionality: | reversible | Curation status: | valid | Classification: | public |
Description: | The enzyme requires Mg2+ and phosphorylation of an aspartate residue at the active site. The enzyme is able to autophosphorylate itself with its substrate beta-D-glucose 1-phosphate. Although this is a slow reaction, only a single turnover is required for activation. Once the phosphorylated enzyme is formed, it generates the reaction intermediate beta-D-glucose 1,6-bisphosphate, which can be used to phosphorylate the enzyme in subsequent cycles. | ||||
Curator notes: |
Substrate
ID Type | Compound ID | Name | Stoichiometry | Curator notes |
---|---|---|---|---|
chebi | 57684 | beta-D-glucose 1-phosphate(2-) | 1 |
Product
ID Type | Compound ID | Name | Stoichiometry | Curator notes |
---|---|---|---|---|
chebi | 58247 | beta-D-glucose 6-phosphate(2-) | 1 |
Schemes
# | Name |
---|---|
83 | beta-phosphoglucomutase, HAD superfamily |