Reaction: beta-phosphoglucomutase List of reactions

Reaction name: beta-phosphoglucomutase Reaction type: cognate
EC number:5.4.2.6 Kegg ID:R02728 Rhea ID:20116
Directionality: reversible Curation status: valid Classification: public
Description:The enzyme requires Mg2+ and phosphorylation of an aspartate residue at the active site. The enzyme is able to autophosphorylate itself with its substrate beta-D-glucose 1-phosphate. Although this is a slow reaction, only a single turnover is required for activation. Once the phosphorylated enzyme is formed, it generates the reaction intermediate beta-D-glucose 1,6-bisphosphate, which can be used to phosphorylate the enzyme in subsequent cycles.
Curator notes:

Substrate

ID Type Compound ID Name Stoichiometry Curator notes
chebi 57684 beta-D-glucose 1-phosphate(2-) 1

Product

ID Type Compound ID Name Stoichiometry Curator notes
chebi 58247 beta-D-glucose 6-phosphate(2-) 1

Reaction

beta-phosphoglucomutase

beta-D-glucose 1-phosphate(2-)
57684
beta-D-glucose 6-phosphate(2-)
58247

EC: 5.4.2.6 | IntEnz: 5.4.2.6 | Kegg: 5.4.2.6 | BioCyc: 5.4.2.6 | BRENDA: 5.4.2.6