Reaction: 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) List of reactions
| Reaction name: | 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) | Reaction type: | cognate | ||
|---|---|---|---|---|---|
| EC number: | 1.1.99.38 | Kegg ID: | Rhea ID: | 34278 | |
| Directionality: | reversible | Curation status: | valid | Classification: | public |
| Description: | Involved in the biosynthetic pathway of the aminoglycoside antibiotics of the butirosin family. | ||||
| Curator notes: | The enzyme from Bacillus circulans was shown to be a radical S-adenosyl-L-methionine (SAM) enzyme. cf. EC 1.1.1.329, 2-deoxy-scyllo-inosamine dehydrogenase. | ||||
Substrate
| ID Type | Compound ID | Name | Stoichiometry | Curator notes |
|---|---|---|---|---|
| chebi | 65003 | 2-deoxy-scyllo-inosamine(1+) | 1 | |
| chebi | 59789 | S-adenosyl-L-methionine zwitterion | 1 |
Product
| ID Type | Compound ID | Name | Stoichiometry | Curator notes |
|---|---|---|---|---|
| chebi | 65002 | 3-ammonio-2,3-dideoxy-scyllo-inosose(1+) | 1 | |
| chebi | 17319 | 5'-deoxyadenosine | 1 | |
| chebi | 57844 | L-methionine zwitterion | 1 | |
| chebi | 15378 | hydron | 1 |
Schemes
| # | Name |
|---|---|
| 107 | 2-deoxy-scyllo-inosamine dehydrogenase, radical SAM superfamily |
Reaction
2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
 |
+ |  |
 |
 |
+ |  |
+ |  |
+ |  |
||
| 2-deoxy-scyllo-inosamine(1+) 65003 |
S-adenosyl-L-methionine zwitterion 59789 |
3-ammonio-2,3-dideoxy-scyllo-inosose(1+) 65002 |
5'-deoxyadenosine 17319 |
L-methionine zwitterion 57844 |
hydron 15378 |
EC: 1.1.99.38 | IntEnz: 1.1.99.38 | Kegg: 1.1.99.38 | BioCyc: 1.1.99.38 | BRENDA: 1.1.99.38