Reaction: spore photoproduct lyase List of reactions

Reaction name: spore photoproduct lyase Reaction type: cognate
EC number:4.1.99.14 Kegg ID: Rhea ID:
Directionality: reversible Curation status: valid Classification: public
Description:The 5'-deoxy-adenosine radical formed after electron transfer from the [4Fe-4S] cluster to the S-adenosyl-L-methionine, initiates the repair by abstracting the C-6 hydrogen of the spore photoproduct lesion. During the second part of the repair process the SAM molecule is regenerated.
Curator notes:

Substrate

ID Type Compound ID Name Stoichiometry Curator notes
chebi 85625 (5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in double-helical DNA) 1

Product

ID Type Compound ID Name Stoichiometry Curator notes
chebi 81146 Two thymine residues (in DNA) 1 thymidylyl-(3'-->5')-thymidylate (in double-helical DNA)

Reaction

spore photoproduct lyase

(5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in double-helical DNA)
85625
Two thymine residues (in DNA)
81146

EC: 4.1.99.14 | IntEnz: 4.1.99.14 | Kegg: 4.1.99.14 | BioCyc: 4.1.99.14 | BRENDA: 4.1.99.14