Structure 3CB8

Enzyme Functional Domain

EFD Name BLAST Pct Identity/
Pct Aligned 		Maps via UniProtKB Superfamily Subgroup Family
Pyruvate formate-lyase 1-activating enzyme 100.0% / 100.0% Yes Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase 1-activating enzyme 100.0% / 100.0% Yes Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme sequence 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme sequence 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 100.0% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.59% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 100.0% / 99.54% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Uncharacterised Radical SAM sequence 99.24% / 100.0% No Radical SAM organic radical-activating enzymes
Pyruvate formate-lyase-activating enzyme 99.18% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.18% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.18% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 99.18% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 98.78% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 98.69% / 99.35% No Radical SAM
Pyruvate formate-lyase-activating enzyme 98.95% / 98.96% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme sequence 97.89% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 97.55% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.55% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.55% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.95% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.95% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.94% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 98.72% / 98.73% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme sequence 97.21% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 97.54% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 97.54% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 97.54% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 97.54% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.54% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Organic radical-activating enzymes subgroup sequence 97.54% / 99.59% No Radical SAM organic radical-activating enzymes
Pyruvate formate-lyase-activating enzyme 97.54% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.54% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.54% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.54% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.54% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.14% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.14% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Organic radical-activating enzymes subgroup sequence 97.14% / 100.0% No Radical SAM organic radical-activating enzymes
Pyruvate formate-lyase-activating enzyme 97.14% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.14% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.14% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.14% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.14% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 98.44% / 98.46% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 97.13% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Organic radical-activating enzymes subgroup sequence 97.13% / 99.59% No Radical SAM organic radical-activating enzymes
Pyruvate formate-lyase-activating enzyme 97.13% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.13% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.13% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.13% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.13% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.13% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.13% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.13% / 99.59% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 96.73% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.73% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Organic radical-activating enzymes subgroup sequence 96.73% / 100.0% No Radical SAM organic radical-activating enzymes
Pyruvate formate-lyase-activating enzyme 96.73% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.73% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.73% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.73% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.73% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.33% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Organic radical-activating enzymes subgroup sequence 96.33% / 100.0% No Radical SAM organic radical-activating enzymes
uncharacterized Organic radical-activating enzymes subgroup sequence 96.33% / 100.0% No Radical SAM organic radical-activating enzymes
Pyruvate formate-lyase-activating enzyme 96.33% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.33% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.33% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.33% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.33% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.33% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.33% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 98.97% / 97.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 95.92% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.92% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.92% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.92% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Organic radical-activating enzymes subgroup sequence 95.92% / 100.0% No Radical SAM organic radical-activating enzymes
uncharacterized Organic radical-activating enzymes subgroup sequence 95.92% / 100.0% No Radical SAM organic radical-activating enzymes
Pyruvate formate-lyase-activating enzyme 95.92% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.92% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.92% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.92% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.92% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.35% / 98.26% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.51% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.51% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.51% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.51% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.51% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.51% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.51% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.51% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.51% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.51% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.42% / 97.98% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 97.46% / 97.93% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Radical SAM superfamily sequence 95.42% / 100.0% No Radical SAM
Pyruvate formate-lyase-activating enzyme 95.1% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
uncharacterized Organic radical-activating enzymes subgroup sequence 95.1% / 100.0% No Radical SAM organic radical-activating enzymes
Pyruvate formate-lyase-activating enzyme 95.1% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.1% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.1% / 100.0% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.43% / 97.51% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 96.0% / 96.15% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Pyruvate formate-lyase-activating enzyme 95.87% / 95.61% No Radical SAM activating enzymes, group 2 pyruvate formate-lyase activase
Percent identity and alignment length from the BLAST match of the Functional Domain sequence to the PDB sequence.
"Yes" indicates that a GI associated with this Functional Domain was mapped to the PDB ID via UniProtKB.
Co-crystallized Molecule(s): Sodium Ion; S-Adenosylmethionine; Iron/Sulfur Cluster; Formic Acid

PDB Molecule Name: Pyruvate Formate-Lyase 1-Activating Enzyme; Peptide Substrate Vsgyav | PDB: 3CB8 | Catalytic Site Atlas: 3CB8