Family known  |
|||||||
| Total |
100% |
<100% |
Family unknown |
||||
| Functional domains | 7847 | 6966 | 70 | 811 | |||
| UniProtKB | 4961 | 0 | 71 | 4890 | |||
| GI | 8072 | 107 | 0 | 7965 | |||
| Structures | 3 | ||||||
| Reactions | 0 | ||||||
| Functional domains of this subgroup were last updated on June 28, 2017 | |||||||
| New functional domains were last added to this subgroup on July 9, 2014 | |||||||
At an E-value of -log10(E) 22 this set of enzymes, all of which create a glycyl radical in the substrate protein, splits into three groups.
Shisler KA, Broderick JB
Glycyl radical activating enzymes: structure, mechanism, and substrate interactions
▸ Abstract
Arch Biochem Biophys 2014;546(None):64-71 | PubMed ID: 24486374
No notes.
Static File Downloads
| File Name | Description | Parameters | Stats |
|---|---|---|---|
| repnet.sg1066.th50.pE20.mek250.xgmml | Representative network: each node is a group of similar sequences | node similarity threshold = 50 max edge count = 250 min -log10 E = 20 |
size = 25M num_edges = 63942 num_nodes = 560 |
| sfld_alignment_sg1066.msa | Annotated Sequence Alignment, Stockholm format | 184 sequences size: 102K |
Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues
| Subgroup ▸ Legend | T |
K |
C |
U |
S |
||
|---|---|---|---|---|---|---|---|
| organic radical-activating enzymes | 7847 | 7036 | 6966 | 811 | 3 | ||
| ┗ 4-hydroxyphenylacetate decarboxylase activase | 7 | 7 | 7 | 0 | |||
| ┗ 1: activating enzymes, group 1 | 2732 | 2721 | 2721 | 11 | 0 | ||
| ┗ anaerobic ribonucleoside-triphosphate reductase activase | 2721 | 2721 | 2721 | 0 | |||
| ┗ 1: activating enzymes, group 2 | 4657 | 4308 | 4238 | 349 | 3 | ||
| ┗ benzylsuccinate synthase activase | 69 | 69 | 69 | 0 | |||
| ┗ glycerol dehydratase activase | 5 | 5 | 5 | 0 | |||
| ┗ pyruvate formate-lyase activase | 3653 | 3653 | 3612 | 3 | |||
| ┗ YjjI activase | 581 | 581 | 552 | 0 |
Depth of the multi-level Subgroup hierarchy.