Top Level Name

  ⌊ Superfamily (core) Enolase

    ⌊ Subgroup enolase

Family known
Total 100% <100% Family unknown
Functional domains 13877 0 13530 347
UniProtKB 28749 0 28511 238
GI 54186 0 53656 530
Structures 70
Reactions 0
Functional domains of this subgroup were last updated on Nov. 22, 2017
New functional domains were last added to this subgroup on May 7, 2015

The enolase group consists of the subset of enolase superfamily enzymes with a Lys at the end of the sixth beta strand that functions in proton abstraction and a Glu at the end of the second beta strand that facilitates departure of the 3-OH group. Currently, the only well-characterized reaction in this group is the enolase reaction.

Babbitt, P.C., et al.

The enolase superfamily: a general strategy for enzyme-catalyzed abstraction of the alpha-protons of carboxylic acids

▸ Abstract

Biochemistry 1996;35(51):16489-16501 | PubMed ID: 8987982

No notes.

Static File Downloads

File Name Description Parameters Stats
repnet.sg178.th50.pE20.mek250.xgmml Representative network: each node is a group of similar sequences node similarity threshold = 50
max edge count = 250
min -log10 E = 20
size = 7.7M
num_edges = 5970
num_nodes = 110
sfld_alignment_sg178.msa Annotated Sequence Alignment, Stockholm format 45 sequences
size: 29K

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues
Subgroup ▸ Legend T K C U S
enolase 13877 13530 0 347 70
┗ enolase 13530 13530 0 60
Depth of the multi-level Subgroup hierarchy.