Top Level Name

  ⌊ Superfamily (core) Nitroreductase

    ⌊ Subgroup SagB

Family known
Total 100% <100% Family unknown
Functional domains 1936 0 0 1936
UniProtKB 0 0 0 0
GI 0 0 0 0
Structures 4
Reactions 0
Functional domains of this subgroup were last updated on Feb. 21, 2017
New functional domains were last added to this subgroup on Dec. 9, 2014

Some members of the diverse SagB subgroup are associated with natural product biosynthesis where they are responsible for azoline oxidation in thiazole/oxazole-modified microcins (TOMMs).

Melby, J. O., Nard, N. J. & Mitchell, D. A.

Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates.

▸ Abstract

Curr Opin Chem Biol. 2011;15(None):369-378 | PubMed ID: 21429787

Melby, J. O., Li, X. & Mitchell, D. A.

Orchestration of Enzymatic Processing by Thiazole/Oxazole-Modified Microcin Dehydrogenases

▸ Abstract

Biochemistry 2014;53(None):413-422 | PubMed ID: 24364559

No notes.

Static File Downloads

File Name Description Parameters Stats
network.sg1232.bs60.mek250K.xgmml One node per sequence network min bit score = 60
max edge count = 250K
size = 131M
num_edges = 250000
num_nodes = 1936
repnet.sg1232.th50.pE20.mek250.xgmml Representative network: each node is a group of similar sequences node similarity threshold = 50
max edge count = 250
min -log10 E = 20
size = 4.4M
num_edges = 10914
num_nodes = 462
sfld_alignment_sg1232.msa Annotated Sequence Alignment, Stockholm format 288 sequences
size: 72K

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues
Subgroup ▸ Legend T K C U S
SagB 1936 0 0 1936 4
┗ 1: SagB 2nd level subgroup 1 270 0 0 270 2
┗ 1: SagB 2nd level subgroup 2 89 0 0 89 0
┗ 1: SagB 2nd level subgroup 3 185 0 0 185 0
┗ 1: SagB 2nd level subgroup 4 152 0 0 152 0
┗ 1: SagB 2nd level subgroup 5 466 0 0 466 0
┗ 1: SagB 2nd level subgroup 6 93 0 0 93 1
┗ 1: SagB 2nd level subgroup 7 681 0 0 681 1
Depth of the multi-level Subgroup hierarchy.