Top Level Name

  ⌊ Superfamily (core) Nitroreductase

    ⌊ Subgroup MhqN

Family known
Total 100% <100% Family unknown
Functional domains 1688 0 0 1688
UniProtKB 0 0 0 0
GI 0 0 0 0
Structures 5
Reactions 0
Functional domains of this subgroup were last updated on June 24, 2017
New functional domains were last added to this subgroup on Nov. 25, 2014

The MhqN Subgroup is a diverse subgroup that contains archaeal, bacterial and eukaryotic sequences (parasitic invertebrates and plants). Enzymes from this subgroup demonstrate a broad substrate range, including reduction of nitroaromatics, quinones, flavins, metals and fatty acids.

Takeda, K. et al.

Synechocystis DrgA protein functioning as nitroreductase and ferric reductase is capable of catalyzing the Fenton reaction.

▸ Abstract

FEBS J 2007;274(None):1318-1327 | PubMed ID: 17298443

Hou, F. et al.

Structure and reaction mechanism of a novel enone reductase.

▸ Abstract

FEBS J. 2015;282(None):1526-1537 | PubMed ID: 25702712

Nguyen, V. D. et al.

Transcriptome and proteome analyses in response to 2-methylhydroquinone and 6-brom-2-vinyl-chroman-4-on reveal different degradation systems involved in the catabolism of aromatic compounds in Bacillus subtilis.

▸ Abstract

Proteomics 2007;7(None):1391-1408 | PubMed ID: 17407181

Töwe, S. et al.

The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis.

▸ Abstract

Mol Microbiol 2007;66(1):40-54 | PubMed ID: 17725564

No notes.

Static File Downloads

File Name Description Parameters Stats
network.sg1226.bs60.mek250K.xgmml One node per sequence network min bit score = 60
max edge count = 250K
size = 130M
num_edges = 250000
num_nodes = 1688
repnet.sg1226.th50.pE20.mek250.xgmml Representative network: each node is a group of similar sequences node similarity threshold = 50
max edge count = 250
min -log10 E = 20
size = 1.8M
num_edges = 2737
num_nodes = 137
sfld_alignment_sg1226.msa Annotated Sequence Alignment, Stockholm format 528 sequences
size: 163K

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues
Subgroup ▸ Legend T K C U S
MhqN 1688 0 0 1688 5
┗ 1: MhqN 2nd level subgroup 1 347 0 0 347 0
┗ 1: MhqN 2nd level subgroup 2 56 0 0 56 0
┗ 1: MhqN 2nd level subgroup 3 106 0 0 106 0
┗ 1: MhqN 2nd level subgroup 4 718 0 0 718 5
┗ 1: MhqN 2nd level subgroup 5 207 0 0 207 0
┗ 1: MhqN 2nd level subgroup 6 100 0 0 100 0
┗ 1: MhqN 2nd level subgroup 7 63 0 0 63 0
┗ 1: MhqN 2nd level subgroup 8 91 0 0 91 0
Depth of the multi-level Subgroup hierarchy.