Top Level Name

  ⌊ Superfamily (core) Radical SAM

    ⌊ Subgroup 7-carboxy-7-deazaguanine synthase like


4NJK (7-carboxy-7-deazaguanine synthase)
Family known
Total 100% <100% Family unknown
Functional domains 4126 1099 2 3025
UniProtKB 15371 0 2812 12559
GI 26337 4786 5 21546
Structures 7
Reactions 0
Functional domains of this subgroup were last updated on June 23, 2017
New functional domains were last added to this subgroup on July 5, 2014

This subgroup is named from the only characterised reaction found within. There appear to be two distinct sets of [4Fe-4S]-AdoMet binding motifs. Although the vast majority have the canonical motif, some appear to contain a Cx14CcxC motif. All appear to have the D,S|T motif after the last AdoMet binding Cys residue suggestive that they all bind a Mg(II) ion.

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues
Subgroup ▸ Legend T K C U S
7-carboxy-7-deazaguanine synthase like 4126 1101 1099 3025 7
┗ 7-carboxy-7-deazaguanine synthase, Cx14CxxC type 509 509 509 5
┗ 7-carboxy-7-deazaguanine synthase, Cx3CxxC type 403 403 402 0
┗ ExsD-like 189 189 188 0
Depth of the multi-level Subgroup hierarchy.