Top Level Name

  ⌊ Superfamily (core) Glutathione Transferase (cytosolic)

    ⌊ Subgroup Main (cytGST)

  ⌊ Main.2: Nu-like

  ⌊ FunctionalDomain Cytosolic GST-like protein, similar to Nu class GSTs (ID 56222)

Superfamily Assignment Evidence Code(s) IEA
This entry was last updated onOct. 14, 2016

References to Other Databases

Genbank

SpeciesGIAccessionProteome
n/a 756613400 AJM25747.1 (Genbank)
Escherichia coli M605 Taxon ID: 656417 331042527 EGI14669.1 (Genbank) URP
Escherichia coli APEC O1 Taxon ID: 405955 115514419 ABJ02494.1 (Genbank) URP
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Uniprot

Protein NameAccessionEC Number Identifier
n/a F4T302 F4T302_ECOLX (TrEMBL)
n/a A0A0H2Z309 A0A0H2Z309_ECOK1 (TrEMBL)
n/a A0A0H2VAT1 A0A0H2VAT1_ECOL6 (TrEMBL)
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Sequence

Length of Enzyme (full-length): 304 | Length of Functional Domain: 222

1       10        20        30        40        50        60

MTCYTASTLPLRRQLTMTDNTYQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHP
LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIPAL
RDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMSWLFWLQGAAPFLGGGFGHF
YHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGNVVLGGV
YDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRINGPLNEQLHERHDASDFETNTED
KRQG
This shows the full-length sequence of the enzyme. The region of the functional domain is highlighted in black letters, while the residual residues are shown in grey. The Superfamily domain, when present, is shown using underlining. In many cases the functional domain is the full-length sequence.
Conserved catalytic residues (as determined by automated alignment to family, subgroup, or superfamily HMMs) are shown with teal highlighting . Conserved catalytic residues which do not matched the Conserved Alignment Residue are shown with maroon highlighting . Information regarding their function can be found in the Conserved Residues section below.
FASTA formatted full-length sequence.
BLAST this sequence against SFLD.
Scan SFLD-HMMs with this sequence.

Structures

PDB ID Title Molecule Name Number of
EFDs		 Resolution (Å) Mutant? Het group Links
3C8E Crystal Structure Analysis Of Yghu From E. Coli Yghu, Glutathione S-Transferase Homologue 41 1.5 Glutathione CSA • PDB • PDBSum
Percent identity and alignment length from the BLAST match of the Functional Domain sequence to the PDB sequence.
"Yes" indicates that a GI associated with this Functional Domain was mapped to the PDB ID via UniProtKB.

Curation History
Time Change Annotation Old Value New Value
May 3, 2014, 6:40 a.m. update curation agent smashiya setDomainBoundaries.py
update domain end position 304 265
Aug. 16, 2016, 8:34 a.m. update domain end position 265 279
update domain start position 61 58
EC number assigned by UniProtKB accession ID.