Top Level Name

  ⌊ Superfamily (core) Isoprenoid Synthase Type II

    ⌊ Subgroup Terpene Cyclase Like 1 N-term

  ⌊ Terpene Cyclase Like 1 N-term - Enzymatic

  ⌊ FunctionalDomain uncharacterized Terpene Cyclase Like 1 N-term subgroup sequence, Isoprenoid Synthase Type II superfamily (ID 315360)

Superfamily Assignment Evidence Code(s) IEA
This entry was last updated onJune 20, 2017

Related Enzyme Functional Domain(s)

uncharacterized Terpene Cyclase Like 1 C-term subgroup sequence, Isoprenoid Synthase Type I superfamily

References to Other Databases

Genbank

SpeciesGIAccessionProteome
Abies balsamea Taxon ID: 90345 343174798 AEL99950.1 (Genbank)
Abies balsamea Taxon ID: 90345 544604144

Uniprot

Protein NameAccessionEC Number Identifier
Bifunctional abietadiene synthase, chloroplastic H8ZM70 4.2.3.18 LAS_ABIBA (Swiss-Prot)

Sequence

Length of Enzyme (full-length): 844 | Length of Functional Domain: 457

1       10        20        30        40        50        60

QSIPHFSTTLNAGSSARKRRSLYLRWGKGSNKIIACVGEGATSVPYQSAEKNDSLYSSTL
VKREFPPGFWKDDLIDSLTSSHKVAASDEKRIETLISEIKNMFRCMGYGETNPSAYDTAW
VARIPALDGSDNPHFPETVEWILQNQLKDGSWGEGFYFLAYDRILATLACIITLTLWRTG
ETQVHKGIEFFRTQAGKMEDEADSHRPSGFEIVFPAMLKEAKILGLDLPYDLPFLKQIIE
KREAKLKRIPTDVLYALPTTLLYSLEGLQEIVDWQKIMKLQSKDGSFLSSPASTAAVFMR
TGNKKCLDFLNFVLKKFGNHVPCHYPLDLFERLWAVDTVERLGIDRHFKEEIKEALDYVY
SHWDERGIGWARENPVPDIDDTAMGLRILRLHGYNVSSDVLKTFRDENGEFFCFLGQTQR
GVTDMLNVNRCSHVSFPGETIMEEAKLCTERYLRNALENVDAFDKWAFKKNIRGEVEYAL
KYPWHKSMPRLEARSYIENYGPDDVWLGKTVYMMPYISNEKYLELAKLDFNKVQSIHQTE
LQDLRRWWKSSGFTDLNFTRERVTEIYFSPASFIFEPEFSKCREVYTKTSNFTVILDDLY
DAHGSLDDLKLFTESVKRWDLSLVDQMPQQMKICFVGFYNTFNEIAKEGRESQGRDVLGY
IQNVWKVQLEAYTKEAEWSEAKYVPSFNEYIENASVSIALGTVVLISALFTGEVLTDEVL
SKIDRGSRFLQLMGLTGRLVNDTKTYQAERGQGEVASAIQCYMKDHPKISEEEALKHVYT
VMENSLEELNREFVNNKIPDIYRRLVFETARIMQLFYMQGDGLTLSHDMEIKEHVKNCLF
QPVA
This shows the full-length sequence of the enzyme. The region of the functional domain is highlighted in black letters, while the residual residues are shown in grey. The Superfamily domain, when present, is shown using underlining. In many cases the functional domain is the full-length sequence.
Conserved catalytic residues (as determined by automated alignment to family, subgroup, or superfamily HMMs) are shown with teal highlighting . Conserved catalytic residues which do not matched the Conserved Alignment Residue are shown with maroon highlighting . Information regarding their function can be found in the Conserved Residues section below.
FASTA formatted full-length sequence.
BLAST this sequence against SFLD.
Scan SFLD-HMMs with this sequence.

Structures

PDB ID Title Molecule Name Number of
EFDs		 Resolution (Å) Mutant? Het group Links
3S9V Abietadiene Synthase From Abies Grandis Abietadiene Synthase, Chloroplastic 10 2.3 CSA • PDB • PDBSum
Percent identity and alignment length from the BLAST match of the Functional Domain sequence to the PDB sequence.
"Yes" indicates that a GI associated with this Functional Domain was mapped to the PDB ID via UniProtKB.

Curation History
Time Change Annotation Old Value New Value
May 2, 2014, 2:59 a.m. update curation agent sbrown setDomainBoundaries.py
update domain end position 504 517
update domain start position 320 61
EC number assigned by UniProtKB accession ID.