Top Level Name

  ⌊ Superfamily (core) Glutathione Transferase (cytosolic)

    ⌊ Subgroup Main (cytGST)

  ⌊ Main.8: Zeta-like

  ⌊ FunctionalDomain Cytosolic GST-like protein, similar to Zeta class GSTs (ID 233591)

Superfamily Assignment Evidence Code(s) IEA
This entry was last updated onMarch 11, 2017

References to Other Databases

Genbank

SpeciesGIAccessionProteome
Macaca fascicularis Taxon ID: 9541 567316101 NP_001274598.1 (RefSeq) URP
Macaca nemestrina Taxon ID: 9545 795449395 XP_011764007.1 (RefSeq)
Macaca mulatta Taxon ID: 9544 297298332 XP_002805178.1 (RefSeq) PRP URP
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Uniprot

Protein NameAccessionEC Number Identifier
n/a A0A1D5RJE8 A0A1D5RJE8_MACMU (TrEMBL)
n/a C0SJM6 C0SJM6_MACFA (TrEMBL)

Sequence

Length of Enzyme (full-length): 217 | Length of Functional Domain: 209

1       10        20        30        40        50        60

MTESGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQV
PALKIDGITIHQSLAIIEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVL
KQVGEEFQLTWAQNAIISGFNALEQILQSTAGTYCVGDEVTMADLCLVPQVANAERFKVD
CTPYPTISSINKRLLVLEAFQVTHPCRQPDTPTELRA
This shows the full-length sequence of the enzyme. The region of the functional domain is highlighted in black letters, while the residual residues are shown in grey. The Superfamily domain, when present, is shown using underlining. In many cases the functional domain is the full-length sequence.
Conserved catalytic residues (as determined by automated alignment to family, subgroup, or superfamily HMMs) are shown with teal highlighting . Conserved catalytic residues which do not matched the Conserved Alignment Residue are shown with maroon highlighting . Information regarding their function can be found in the Conserved Residues section below.
FASTA formatted full-length sequence.
BLAST this sequence against SFLD.
Scan SFLD-HMMs with this sequence.

Structures

PDB ID Title Molecule Name Number of
EFDs		 Resolution (Å) Mutant? Het group Links
1FW1 Glutathione Transferase Zeta/Maleylacetoacetate Isomerase Glutathione Transferase Zeta 14 1.9 Sulfate Ion
(2 more ⇓) 		CSA • PDB • PDBSum
Percent identity and alignment length from the BLAST match of the Functional Domain sequence to the PDB sequence.
"Yes" indicates that a GI associated with this Functional Domain was mapped to the PDB ID via UniProtKB.

Curation History
Time Change Annotation Old Value New Value
Aug. 16, 2016, 8:28 a.m. update curation agent smashiya setDomainBoundaries.py
update domain end position 199 213
update domain start position 7 5
EC number assigned by UniProtKB accession ID.