| Total |
100%  |
<100% |
Family unknown |
||||
| Functional domains | 525 | ||||||
| UniProtKB | 2824 | 0 | 0 | 2824 | |||
| GI | 5857 | 0 | 0 | 5857 | |||
| Structures | 11 | ||||||
| Reactions | 0 | ||||||
| Functional domains of this subgroup were last updated on March 11, 2017 | |||||||
| New functional domains were last added to this subgroup on June 22, 2012 | |||||||
Cytosolic GSTs that include proteins with "Zeta" Swiss-Prot family annotations. Proteins in this subgroup are known to catalyze the following reaction types: conjugate addition, hydrolytic dehalogenation, isomerization, nucleophilic aromatic substitution, nucleophilic substitution (SN2), peroxidase, and thiolysis reactions. For example, SFLD protein 226008 (UniProt accn O43708) has experimentally-confirmed isomerization activity with maleylacetoacetate; conjugate addition activity with ethacrynic acid; hydrolytic dehalogenation activity with dichloroacetate and chlorofluoroacetate; nucleophilic aromatic substitution activity with 7-chloro-4-nitrobenz-2oxa-1,3-diazole; nucleophilic substitution (SN2) activity with S-2-chloroproprionate, R-2-chloroproprionate, and fluoroacetate; peroxidase activity with cumene hydroperoxide and t-butyl hydroperoxide; and thiolysis activity with p-nitrophenyl acetate. For another example, SFLD protein 233211 (UniProt accn O86043) has experimentally-confirmed malelylpyruvate isomerase activity.
No References.
No notes.
Static File Downloads
| File Name | Description | Parameters | Stats |
|---|---|---|---|
| sfld_alignment_sg1157.msa | Annotated Sequence Alignment, Stockholm format | 89 sequences size: 23K |
| Subgroup ▸ Legend | T |
S |
||
|---|---|---|---|---|
| ┗ 1: Main.8: Zeta-like | 525 | 11 |