Top Level Name

  ⌊ Superfamily (core) Nitroreductase

    ⌊ Subgroup ACG

Family known
Total 100% <100% Family unknown
Functional domains 773 0 0 773
UniProtKB 0 0 0 0
GI 0 0 0 0
Structures 1
Reactions 0
Functional domains of this subgroup were last updated on Feb. 21, 2017
New functional domains were last added to this subgroup on Nov. 25, 2014

The Acg Subgroup, includes one of the most highly upregulated genes in the switch between dormant and active tuberculosis. Deletion of the Acg genes associated with the dormancy regulon in Mycobacterium tuberculosis renders a mutant that can no longer infect activated macrophage cell lines or immune compromised mice.

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues
Subgroup ▸ Legend T K C U S
ACG 773 0 0 773 1
┗ 1: ACG 2nd level subgroup 1 51 0 0 51 0
┗ 1: ACG 2nd level subgroup 2 568 0 0 568 1
┗ 1: ACG 2nd level subgroup 3 154 0 0 154 0
Depth of the multi-level Subgroup hierarchy.