Top Level Name

  ⌊ Superfamily (core) Nitroreductase

    ⌊ Subgroup FeS

Family known
Total 100% <100% Family unknown
Functional domains 529 0 0 529
UniProtKB 0 0 0 0
GI 0 0 0 0
Structures 0
Reactions 0
Functional domains of this subgroup were last updated on Feb. 21, 2017
New functional domains were last added to this subgroup on Nov. 25, 2014

The FeS Subgroup is characterized by an N-terminal fusion to a ferredoxin domain. Two FeS subgroup enzymes have been characterized from G. Lamblia and can catalyze the anaerobic reduction of quinones, flavins, nitroaromatics.

Müller, J. et al.

Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds.

▸ Abstract

Int J Parasitol Drugs Drug Resist. 2015;5(None):37-43 | PubMed ID: 27099829

No notes.

Static File Downloads

File Name Description Parameters Stats
network.sg1220.bs60.mek250K.xgmml One node per sequence network min bit score = 60
max edge count = 250K
size = 70M
num_edges = 134449
num_nodes = 529
repnet.sg1220.th50.pE20.mek250.xgmml Representative network: each node is a group of similar sequences node similarity threshold = 50
max edge count = 250
min -log10 E = 20
size = 2.5M
num_edges = 7304
num_nodes = 138
sfld_alignment_sg1220.msa Annotated Sequence Alignment, Stockholm format 180 sequences
size: 56K

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues
Subgroup ▸ Legend T K C U S
FeS 529 0 0 529 0
┗ 1: FeS 2nd level subgroup 1 295 0 0 295 0
┗ 1: FeS 2nd level subgroup 2 180 0 0 180 0
┗ 1: FeS 2nd level subgroup 3 39 0 0 39 0
┗ 1: FeS 2nd level subgroup 4 15 0 0 15 0
Depth of the multi-level Subgroup hierarchy.