Top Level Name

  ⌊ Superfamily (core) Glutathione Transferase (cytosolic)

    ⌊ Subgroup Main (cytGST)

  ⌊ Main.4: Theta-like


1JLV (glutathione transferase GST1-3)
Total 100% <100% Family unknown
Functional domains 806
UniProtKB 866 0 0 866
GI 1740 0 0 1740
Structures 35
Reactions 0
Functional domains of this subgroup were last updated on June 10, 2017
New functional domains were last added to this subgroup on June 22, 2012

Cytosolic GSTs that include proteins with "Theta" Swiss-Prot family annotations. Proteins in this subgroup are known to catalyze the following reaction types: conjugate addition, epoxide ring opening, hydrolytic dehalogenation, nucleophilic addition, nucleophilic aromatic substitution, nucleophilic substitution (SN2), peroxidase, and thiolysis reactions. For example, SFLD protein 55995 (UniProt accn P20432) has experimentally-confirmed conjugate addition activity with ethacrynic acid; nucleophilic aromatic substitution activity with CDNB and DCNB (dichloronitrobenzene); and peroxidase activity with 4-hydroperoxy-2-nonenal. It additionally has DDT-dehydrochlorinase activity with the synthetic pesticide and environmental pollutant DDT.

No References.

No notes.

Static File Downloads

File Name Description Parameters Stats
sfld_alignment_sg1153.msa Annotated Sequence Alignment, Stockholm format 83 sequences
size: 25K

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues
Subgroup ▸ Legend T S
┗ 1: Main.4: Theta-like 806 35
Depth of the multi-level Subgroup hierarchy.