Top Level Name

  ⌊ Superfamily (core) Enolase

    ⌊ Subgroup glucarate dehydratase

     ⌊ Family glucarate dehydratase


1ECQ (glucarate dehydratase)
Total 100% <100%
Functional domains 3585 0 3585
UniProtKB 8513 0 8513
GI 16063 0 16063
Structures 22
Reactions 1
Functional domains of this family were last updated on Nov. 22, 2017
New functional domains were last added to this family on May 7, 2015

Enzymes in the glucarate dehydratase family catalyze the dehydration of both d-glucarate and l-idarate to form 5-keto-4-deoxy-d-glucarate. Characterized enzymes in this family also perform the glucarate to idarate and idarate to glucarate epimerization reactions.

No References.

No notes.

Static File Downloads

File Name Description Parameters Stats
repnet.fam5.th50.pE20.mek250K.xgmml Representative network: each node is a group of similar sequences node similarity threshold = 50
max edge count = 250K
min -log10 E = 20		 size = 1.5M
num_edges = 21
num_nodes = 7
sfld_alignment_fam5.msa Annotated Sequence Alignment, Stockholm format 20 sequences
size: 12K

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues

Active Site

Catalyzed Reaction(s)

glucarate dehydratase

+
D-glucarate(2-)
30612		 5-dehydro-4-deoxy-D-glucarate(2-)
42819		 water
15377

EC: 4.2.1.40 | IntEnz: 4.2.1.40 | Kegg: 4.2.1.40 | BioCyc: 4.2.1.40 | BRENDA: 4.2.1.40