Top Level Name

  ⌊ Superfamily (core) Enolase

    ⌊ Subgroup mandelate racemase

     ⌊ Family L-talarate/galactarate dehydratase

Total 100% <100%
Functional domains 319 0 319
UniProtKB 1085 0 1085
GI 2725 0 2725
Structures 5
Reactions 3
Functional domains of this family were last updated on Nov. 22, 2017
New functional domains were last added to this family on May 7, 2015

Enzymes in the L-talarate/galactarate dehydratase family catalyze the dehydration of L-talarate, the dehydration of galactarate, and the epimerization of L-talarate to galactarate.

Yew WS, Fedorov AA, Fedorov EV, Almo SC, Gerlt JA

Evolution of Enzymatic Activities in the Enolase Superfamily: l-Talarate/Galactarate Dehydratase from Salmonella typhimurium LT2

▸ Abstract

Biochemistry 2007;46(33):9564-9577 | PubMed ID: 17649980

No notes.

Static File Downloads

File Name Description Parameters Stats
network.fam134.bs60.mek250K.xgmml One node per sequence network min bit score = 60
max edge count = 250K
size = 17M
num_edges = 50721
num_nodes = 319
sfld_alignment_fam134.msa Annotated Sequence Alignment, Stockholm format 4 sequences
size: 3.1K

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues

Active Site

Catalyzed Reaction(s)

galactarate dehydratase

+
galactarate(2-)
16537
5-dehydro-4-deoxy-D-glucarate(2-)
42819
water
15377

EC: 4.2.1.42 | IntEnz: 4.2.1.42 | Kegg: 4.2.1.42 | BioCyc: 4.2.1.42 | BRENDA: 4.2.1.42

L-talarate dehydratase

+
L-altrarate(2-)
37547
5-dehydro-4-deoxy-D-glucarate(2-)
42819
water
15377

EC: 4.2.1.156 | IntEnz: 4.2.1.156 | Kegg: 4.2.1.156 | BioCyc: 4.2.1.156 | BRENDA: 4.2.1.156

L-talarate epimerase

L-altrarate(2-)
37547
galactarate(2-)
16537

EC: 5.1.-.- | IntEnz: 5.1.-.- | Kegg: 5.1.-.- | BioCyc: 5.1.-.- | BRENDA: 5.1.-.- |