Top Level Name

  ⌊ Superfamily (core) Enolase

    ⌊ Subgroup mandelate racemase

     ⌊ Family L-fuconate dehydratase

Total 100% <100%
Functional domains 1191 0 1191
UniProtKB 1263 0 1263
GI 3039 0 3039
Structures 7
Reactions 1
Functional domains of this family were last updated on Nov. 22, 2017
New functional domains were last added to this family on May 7, 2015

Enzymes in the L-fuconate dehydratase family catalyze the dehydration of L-fuconate to 2-keto-3-deoxy-L-fuconate, as part of the L-fucose catabolic pathway.

Yew WS, Fedorov AA, Fedorov EV, Rakus JF, Pierce RW, Almo SC, Gerlt JA

Evolution of Enzymatic Activities in the Enolase Superfamily: l-Fuconate Dehydratase from Xanthomonas campestris

▸ Abstract

Biochemistry 2006;45(49):14582-14597 | PubMed ID: 17144652

No notes.

Static File Downloads

File Name Description Parameters Stats
network.fam111.bs60.mek250K.xgmml One node per sequence network min bit score = 60
max edge count = 250K
size = 83M
num_edges = 250000
num_nodes = 1191
sfld_alignment_fam111.msa Annotated Sequence Alignment, Stockholm format 108 sequences
size: 55K

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues

Active Site

Catalyzed Reaction(s)

L-fuconate dehydratase

+
L-fuconate
21291
2-dehydro-3-deoxy-L-fuconate
37448
water
15377

EC: 4.2.1.68 | IntEnz: 4.2.1.68 | Kegg: 4.2.1.68 | BioCyc: 4.2.1.68 | BRENDA: 4.2.1.68