Top Level Name

  ⌊ Superfamily (core) Isoprenoid Synthase Type I

    ⌊ Subgroup Trichodiene Synthase Like

     ⌊ Family trichodiene synthase


1JFG (trichodiene synthase)
Total 100% <100%
Functional domains 43 31 12
UniProtKB 56 49 7
GI 151 101 50
Structures 20
Reactions 0
Functional domains of this family were last updated on June 10, 2017
New functional domains were last added to this family on Aug. 2, 2014

Members of the trichodiene family catalyze the formation of trichodiene from farnesyl diphosphate. Trichodiene is the first committed step in the biosynthesis of many toxins and antibiotics produced by fungi.

Rynkiewicz MJ, Cane DE, Christianson DW

Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade

▸ Abstract

Proc Natl Acad Sci 2001;98(24):13543-13548 | PubMed ID: 11698643

Cane DE

Enzymic formation of sesquiterpenes

▸ Abstract

Chem Rev 1990;90(7):1089-1103 | PubMed ID: None

289 = ref for mechanism.

Static File Downloads

File Name Description Parameters Stats
sfld_alignment_fam102.msa Annotated Sequence Alignment, Stockholm format 22 sequences
size: 11K

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues

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