Top Level Name

  ⌊ Superfamily (core) Radical SAM

    ⌊ Subgroup B12-binding domain containing

  ⌊ methyltransferase (Class B)

     ⌊ Family bacteriochlorophyll C12 methyltransferase

  ⌊ FunctionalDomain bacteriochlorophyll C12 methyltransferase, BchR (ID 410811)

Superfamily Assignment Evidence Code(s) ISS
Family Assignment Evidence Code CFM PubMed:19297239
This entry was last updated onJune 10, 2017

References to Other Databases

Genbank

SpeciesGIAccessionProteome
Chlorobium tepidum TLS Taxon ID: 194439 21674143 NP_662208.1 (RefSeq) URP
Chlorobaculum tepidum Taxon ID: 1097 499235449 WP_010932989.1 (RefSeq)

Sequence

Length of Enzyme (full-length): 468 | Length of Functional Domain: 468

1       10        20        30        40        50        60

MLTDDLQTAESSVSLTNGVAPSLEKLAAEQKSRKKWLLVQPKSQTSMMVDSGAVSMPLNL
IMVATLASKYFDVTFLDERTGDTIPQDFSGYDVVAITSRTLNAKNAYRIGDRAKAQGKIV
LIGGVHPTMLTDEASLHCTSVIYGEIESVWEELAIDIFRGKMKSVYKASNLKPMTTMTPP
DFSFALNSPHAKKYSQLIPILATKGCPVGCSFCTTPTVYGKSFRYREIDLVLDEMRAHQE
RLGKKKVRFSFMDDNISFRPKYFMELLEGMAKLGVRWNANISMNFLQKPEVAELAGRSGC
ELMSIGFESLNPDILKSMNKGSNRLQNYEAVVSNLHKHKIAIQGYFIFGFDDDSEKSFQA
TYDFIMQNRIEFPVFSLLTPFPGTPYFEEMKDRVRHFDWDKYDTYHYMFEPKKLGGEKLL
ENFIKLQREVYKGSAIMKRMQGKPLNWVWFVNFLMNRFTRKLTPEMYL
This shows the full-length sequence of the enzyme. The region of the functional domain is highlighted in black letters, while the residual residues are shown in grey. The Superfamily domain, when present, is shown using underlining. In many cases the functional domain is the full-length sequence.
Conserved catalytic residues (as determined by automated alignment to family, subgroup, or superfamily HMMs) are shown with teal highlighting . Conserved catalytic residues which do not matched the Conserved Alignment Residue are shown with maroon highlighting . Information regarding their function can be found in the Conserved Residues section below.
FASTA formatted full-length sequence.
BLAST this sequence against SFLD.
Scan SFLD-HMMs with this sequence.

Conserved Residues
Superfamily CAR This EFD conserves 3/3 Superfamily-specific Conserved Alignment Residues.
Position Amino Acid Location Function Role Evidence Code Reference
206 Cys (C) side chain Binds [4Fe-4S]-AdoMet cluster cofactor binding -- binding ISS
210 Cys (C) side chain Binds [4Fe-4S]-AdoMet cluster cofactor binding -- binding ISS
213 Cys (C) side chain Binds [4Fe-4S]-AdoMet cluster cofactor binding -- binding ISS
Subgroup CAR This EFD conserves 3/3 Subgroup-specific Conserved Alignment Residues.
Position Amino Acid Location Function Role Evidence Code Reference
206 Cys (C) side chain Binds [4Fe-4S]-AdoMet cluster cofactor binding -- binding ISS
210 Cys (C) side chain Binds [4Fe-4S]-AdoMet cluster cofactor binding -- binding ISS
213 Cys (C) side chain Binds [4Fe-4S]-AdoMet cluster cofactor binding -- binding ISS
Family CAR This EFD conserves 3/3 Family-specific Conserved Alignment Residues.
Position Amino Acid Location Function Role Evidence Code Reference
206 Cys (C) side chain Binds [4Fe-4S]-AdoMet cluster cofactor binding -- binding IEA
210 Cys (C) side chain Binds [4Fe-4S]-AdoMet cluster cofactor binding -- binding IEA
213 Cys (C) side chain Binds [4Fe-4S]-AdoMet cluster cofactor binding -- binding IEA

Catalyzed Reaction

bacteriochlorophyll C12 methyltransferase

2 + + + +
S-adenosyl-L-methionine zwitterion
59789		 Bacteriochlorophyll d
81553		 Bacteriochlorophyll d
81553		 S-adenosyl-L-homocysteine zwitterion
57856		 L-methionine zwitterion
57844		 5'-deoxyadenosine
17319

EC: | IntEnz: | Kegg: | BioCyc: | BRENDA: |

Curation History
Time Change Annotation Old Value New Value
May 14, 2014, 2:58 a.m. update curation agent holliday setDomainBoundaries.py
update domain end position 397 468
update domain start position 155 1
Oct. 15, 2016, 6:07 a.m. update curation agent setDomainBoundaries.py holliday
update curation agent holliday setDomainBoundaries.py
update name BchR Sequence bacteriochlorophyll C12 methyltransferase, BchR
EC number assigned by UniProtKB accession ID.