Top Level Name
⌊ Superfamily (core) Isoprenoid Synthase Type II
⌊ Subgroup Prenyltransferase Like 2
⌊ Family private
⌊ FunctionalDomain Lanosterol Synthase (ID 3839)
No Notes.
Superfamily Assignment Evidence Code(s) | FSM PubMed:7639730 |
Family Assignment Evidence Code | CFM PubMed:7639730 |
This entry was last updated on | June 10, 2017 |
References to Other Databases
Genbank
Species | GI | Accession | Proteome |
---|---|---|---|
Homo sapiens Taxon ID: 9606 | 47933397 | NP_001001438.1 (RefSeq) | PRP URP |
Homo sapiens Taxon ID: 9606 | 47933395 | NP_002331.3 (RefSeq) | PRP URP |
n/a | 756729057 | AJM55996.1 (Genbank) | |
n/a | 568530614 | AHD73106.1 (Genbank) | |
n/a | 568530613 | AHD73105.1 (Genbank) | |
n/a | 550843341 | AGY09318.1 (Genbank) | |
n/a | 550843235 | AGY09212.1 (Genbank) | |
n/a | 335927724 | AEH74443.1 (Genbank) | |
Homo sapiens Taxon ID: 9606 | 119629707 | EAX09302.1 (Genbank) | PRP URP |
Homo sapiens Taxon ID: 9606 | 119629706 | EAX09301.1 (Genbank) | PRP URP |
Homo sapiens Taxon ID: 9606 | 119629704 | EAX09299.1 (Genbank) | PRP URP |
n/a | 53932089 | AAV00414.1 (Genbank) | |
Homo sapiens Taxon ID: 9606 | 1336837 | AAB36220.1 (Genbank) | PRP URP |
Homo sapiens Taxon ID: 9606 | 951314 | AAC50184.1 (Genbank) | PRP URP |
Homo sapiens Taxon ID: 9606 | 300591871 | PRP URP | |
Homo sapiens Taxon ID: 9606 | 300591681 | PRP URP | |
Homo sapiens Taxon ID: 9606 | 259708496 | PRP URP | |
Homo sapiens Taxon ID: 9606 | 259705681 | PRP URP | |
Homo sapiens Taxon ID: 9606 | 227483932 | PRP URP | |
Homo sapiens Taxon ID: 9606 | 56966681 | PRP URP | |
Homo sapiens Taxon ID: 9606 | 1352387 | PRP URP | |
Homo sapiens Taxon ID: 9606 | 1019366 | PRP URP | |
obsolete GI = 578836540 | |||
Show All |
Uniprot
Protein Name | Accession | EC Number
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Identifier |
---|---|---|---|
Lanosterol synthase | P48449 | 5.4.99.7 | ERG7_HUMAN (Swiss-Prot) |
Length of Enzyme (full-length): 732 | Length of Functional Domain: 729
MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDT
KNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLP
AGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNIL
HKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPM
SYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALL
NLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQE
HVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRL
SQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPR
ERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA
LKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMG
QTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLM
AVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFS
QLYPERALAGHP
Conserved catalytic residues (as determined by automated alignment to family, subgroup, or superfamily HMMs) are shown with teal highlighting . Conserved catalytic residues which do not matched the Conserved Alignment Residue are shown with maroon highlighting . Information regarding their function can be found in the Conserved Residues section below.