Top Level Name

  ⌊ Superfamily (core) Radical SAM

    ⌊ Subgroup antiviral proteins

Family known
Total 100% <100% Family unknown
Functional domains 312 196 2 114
UniProtKB 254 0 150 104
GI 552 341 3 208
Structures 0
Reactions 0
Functional domains of this subgroup were last updated on June 10, 2017
New functional domains were last added to this subgroup on Oct. 7, 2014

This group of enzymes includes the antiviral protein Viperin.

Duschene KS, Broderick JB

The antiviral protein viperin is a radical SAM enzyme

▸ Abstract

FEBS Lett. 2012;584(6):1263-1267 | PubMed ID: 20176015

Haldar S, Paul S, Joshi N, Dasgupta A, Chattopadhyay K

The presence of the iron-sulfur motif is important for the conformational stability of the antiviral protein, Viperin.

▸ Abstract

PLoS One 2012;7(2):None-None | PubMed ID: 22363738

No notes.

Static File Downloads

File Name Description Parameters Stats
network.sg1088.bs60.mek250K.xgmml One node per sequence network min bit score = 60
max edge count = 250K		 size = 25M
num_edges = 48021
num_nodes = 312
repnet.sg1088.th50.pE20.mek250.xgmml Representative network: each node is a group of similar sequences node similarity threshold = 50
max edge count = 250
min -log10 E = 20		 size = 500K
num_edges = 1018
num_nodes = 51
sfld_alignment_sg1088.msa Annotated Sequence Alignment, Stockholm format 74 sequences
size: 33K

Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues
Subgroup ▸ Legend T K C U S
antiviral proteins 312 198 196 114 0
┗ Viperin 198 198 196 0
Depth of the multi-level Subgroup hierarchy.