Reaction Scheme: methylaspartate ammonia-lyase, Enolase superfamily Reaction 2

Scheme name: methylaspartate ammonia-lyase, Enolase superfamily
Reaction: methylaspartate ammonia-lyase
Description:Enzymes in this reaction scheme are all members of the enoalse superfamily, and as such have an absolute requirement for a divalent metal cation.
Curator notes:EC and GO all suggest that these enzymes are also cobalamin binding. However, none of the PDB codes for the linked EFD have cobalamin bound. Could be indicative of two (or more) superfamilies performing this overall chemical transformation.

Database References

DB Name DB Identifier Evidence Code Evidence Code Reference
SFLD EFD 41 IDA 282

Reaction

methylaspartate ammonia-lyase

+
threo-3-methyl-L-aspartate(1-)
58724
mesaconate(2-)
36986
ammonium
28938

EC: 4.3.1.2 | IntEnz: 4.3.1.2 | Kegg: 4.3.1.2 | BioCyc: 4.3.1.2 | BRENDA: 4.3.1.2