Top Level Name
⌊ Superfamily (core) Radical SAM
⌊ Subgroup SPASM/twitch domain containing
⌊ Family pcfB-like
| Total |
100%  |
<100% |
|||
| Functional domains | 1 | 0 | 1 | ||
| UniProtKB | 1 | 0 | 1 | ||
| GI | 1 | 0 | 1 | ||
| Structures | 0 | ||||
| Reactions | 0 | ||||
| Functional domains of this family were last updated on June 10, 2017 | |||||
| New functional domains were last added to this family on Aug. 17, 2012 | |||||
Brede et al. suggest that the canonical member of this family is involved in releasing the N terminus of propionicin F by generating an unstable radical on the cys101 residue of the probacteriocin. This is suggested as Propionicin F is not a cyclic molecule (ruling out the pfcB acting in ring formation or thioether bond formation), and the bacteriocin does not contain any modified residues.
Brede DA, Faye T, Johnsborg O, Odegård I, Nes IF, Holo H
Molecular and genetic characterization of propionicin F, a bacteriocin from Propionibacterium freudenreichii
▸ Abstract
Appl Environ Microbiol 2004;70(12):7303-7310 | PubMed ID: 15574930
There do not currently appear to be any other enzymes in the available sequence databases with enough similarity to pcfB to warrant adding any other sequences to this family; hence there is only one sequence in the family and alignment.
Static File Downloads
| File Name | Description | Parameters | Stats |
|---|---|---|---|
| network.fam569.bs60.mek250K.xgmml | One node per sequence network | min bit score = 60 max edge count = 250K |
size = 2.1K num_edges = 0 num_nodes = 1 |
| sfld_alignment_fam569.msa | Annotated Sequence Alignment, Stockholm format | 1 sequences size: 635 |