| Total |
100%  |
<100% |
|||
| Functional domains | 903 | 903 | 0 | ||
| UniProtKB | 1049 | 1049 | 0 | ||
| GI | 2233 | 2233 | 0 | ||
| Structures | 0 | ||||
| Reactions | 0 | ||||
| Functional domains of this family were last updated on June 10, 2017 | |||||
| New functional domains were last added to this family on July 5, 2014 | |||||
CDK5RAP1 is a radical SAM enzyme, which postsynthetically converts the RNA modification N6-isopentenyladenosine (i(6)A) into 2-methylthio-N6-isopentenyladenosine (ms(2)i(6)A). This conversion is not limited to mitochondrial tRNA, CDK5RAP1 also introduces the modification into nuclear RNA species establishing a link between postsynthetic kinase-based protein modification and postsynthetic RNA modification.
Reiter V, Matschkal DM, Wagner M, Globisch D, Kneuttinger AC, Müller M, Carell T
The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA
▸ Abstract
Nucleic Acids Res 2012;40(13):6235-6240 | PubMed ID: 22422838
No notes.
Static File Downloads
| File Name | Description | Parameters | Stats |
|---|---|---|---|
| network.fam413.bs60.mek250K.xgmml | One node per sequence network | min bit score = 60 max edge count = 250K |
size = 129M num_edges = 250000 num_nodes = 903 |
| sfld_alignment_fam413.msa | Annotated Sequence Alignment, Stockholm format | 105 sequences size: 120K |
Total number of functional domains in this group.
Number of Functional Domains that have been manually or automatically been assigned to a family.
Number of Functional Domains that have not been assigned to a family.
Number of structures available from the PDB for members of this group.
Number of Functional Domains with 100% of Conserved Residues
Number of Functional Domains with less than 100% Conserved Residues