Top Level Name

  ⌊ Superfamily (core) Isoprenoid Synthase Type I

 ⌊ Structures There are 94 unique sequences represented by 412 PDB crystal structures

Accession IDs PDB ID Title Molecule Name Number of
EFDs
Resolution (Å) Mutant? Het group Chimera Session Links
Q40577 5EAT 5-Epi-Aristolochene Synthase From Nicotiana Tabacum With Substrate Analog Farnesyl Hydroxyphosphonate 5-Epi-Aristolochene Synthase 32 2.8 Magnesium Ion • 1-Hydroxy-3,7,11-Trimethyldodeca-2,6,10-Triene Phosphonic Acid CSA • PDB • PDBSum
1HX9 Crystal Structure Of Teas W273S Form 1 5-Epi-Aristolochene Synthase 28 3.5 Yes Magnesium Ion • 1-Hydroxy-3,7,11-Trimethyldodeca-2,6,10-Triene Phosphonic Acid CSA • PDB • PDBSum
1HXA Crystal Structure Of Teas W273S Form 2 5-Epi-Aristolochene Synthase 28 2.32 Yes Magnesium Ion • 1-Hydroxy-3,7,11-Trimethyldodeca-2,6,10-Triene Phosphonic Acid CSA • PDB • PDBSum
1HXC Crystal Structure Of Teas C440W 5-Epi-Aristolochene Synthase 28 2.25 Yes 1-Hydroxy-3,7,11-Trimethyldodeca-2,6,10-Triene Phosphonic Acid CSA • PDB • PDBSum
1HXG Crystal Structure Of Teas W273S/C440W 5-Epi-Aristolochene Synthase 28 2.9 Yes Magnesium Ion CSA • PDB • PDBSum
5EAS 5-Epi-Aristolochene Synthase From Nicotiana Tabacum 5-Epi-Aristolochene Synthase 33 2.25 Yes Magnesium Ion CSA • PDB • PDBSum
5EAU 5-Epi-Aristolochene Synthase From Nicotiana Tabacum 5-Epi-Aristolochene Synthase 30 2.15 Yes Magnesium Ion • Trifluorofurnesyl Diphosphate CSA • PDB • PDBSum
3M01 The Crystal Structure Of 5-Epi-Aristolochene Synthase Complexed With (2-Trans,6-Trans)-2-Fluorofarnesyl Diphosphate Aristolochene Synthase 30 2.6 (2Z,6E)-2-Fluoro-3,7,11-Trimethyldodeca-2,6,10-Trien-1-Yl Trihydrogen Diphosphate
(2 more ⇓)
CSA • PDB • PDBSum
3M02 The Crystal Structure Of 5-Epi-Aristolochene Synthase Complexed With (2-Cis,6-Trans)-2-Fluorofarnesyl Diphosphate Aristolochene Synthase 30 2.5 Magnesium Ion • (2E,6E)-2-Fluoro-3,7,11-Trimethyldodeca-2,6,10-Trien-1-Yl Trihydrogen Diphosphate CSA • PDB • PDBSum
3M00 Crystal Structure Of 5-Epi-Aristolochene Synthase M4 Mutant Complexed With (2-Cis,6-Trans)-2-Fluorofarnesyl Diphosphate Aristolochene Synthase 28 2.1 Yes (2E,6E)-2-Fluoro-3,7,11-Trimethyldodeca-2,6,10-Trien-1-Yl Trihydrogen Diphosphate • Magnesium Ion CSA • PDB • PDBSum
3LZ9 The Crystal Structure Of 5-Epi-Aristolochene Synthase M4 Mutant Complexed With (2-Trans,6-Trans)-2-Fluorofarnesyl Diphosphate Aristolochene Synthase 28 2.28 Yes (2Z,6E)-2-Fluoro-3,7,11-Trimethyldodeca-2,6,10-Trien-1-Yl Trihydrogen Diphosphate • Magnesium Ion CSA • PDB • PDBSum
4DI5 Co-Crystal Structure Of Wt 5-Epi-Aristolochene Synthase From Nicotiana Tobaccum With Geraniline 5-Epi-Aristolochene Synthase 30 2.3 Acetate Ion
(3 more ⇓)
CSA • PDB • PDBSum
4RNQ Crystal Structure Of Tobacco 5-Epi-Aristolochene Synthase (Teas) With Anilinogeranyl Diphosphate (Agpp) And Geraniline 5-Epi-Aristolochene Synthase 30 2.47 Magnesium Ion
(4 more ⇓)
CSA • PDB • PDBSum
Q03471 1DI1 Crystal Structure Of Aristolochene Synthase From Penicillium Roqueforti Aristolochene Synthase 4 2.5 CSA • PDB • PDBSum
1DGP Aristolochene Synthase Farnesol Complex Aristolochene Synthase 4 2.8 Farnesol CSA • PDB • PDBSum
Q55012 1PS1 Pentalenene Synthase Pentalenene Synthase 2 2.6 Trimethyl Lead Ion CSA • PDB • PDBSum
1HM4 N219L Pentalenene Synthase Pentalenene Synthase 2 3.47 Yes CSA • PDB • PDBSum
1HM7 N219L Pentalenene Synthase Pentalenene Synthase 2 2.9 Yes CSA • PDB • PDBSum
P13513 Q7LP67 1JFA Trichodiene Synthase From Fusarium Sporotrichioides Trichodiene Synthase 20 2.5 1,2-Ethanediol CSA • PDB • PDBSum
1JFG Trichodiene Synthase From Fusarium Sporotrichioides Complexed With Diphosphate Trichodiene Synthase 20 2.5 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
1KIY D100E Trichodiene Synthase Trichodiene Synthase 19 2.4 Yes 1,2-Ethanediol CSA • PDB • PDBSum
1KIZ D100E Trichodiene Synthase Complexed With Pyrophosphate Trichodiene Synthase 19 2.6 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2PS7 Y295F Trichodiene Synthase Trichodiene Synthase 19 2.35 Yes Magnesium Ion • 1,2-Ethanediol CSA • PDB • PDBSum
2PS8 Y295F Trichodiene Synthase: Complex With Mg And Pyrophosphate Trichodiene Synthase 19 2.67 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2AEL R304K Trichodiene Synthase: Complex With Mg, Pyrophosphate, And (4R)-7-Azabisabolene Trichodiene Synthase 19 2.5 Yes Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
2AET R304K Trichodiene Synthase: Complex With Mg, Pyrophosphate, And (4S)-7-Azabisabolene Trichodiene Synthase 19 2.75 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2AEK R304K Trichodiene Synthase Trichodiene Synthase 19 2.9 Yes Magnesium Ion • 1,2-Ethanediol CSA • PDB • PDBSum
1YYQ Y305F Trichodiene Synthase Complexed With Pyrophosphate Trichodiene Synthase 19 2.1 Yes Magnesium Ion • Pyrophosphate 2- CSA • PDB • PDBSum
1YYS Y305F Trichodiene Synthase: Complex With Mg, Pyrophosphate, And (4S)-7-Azabisabolene Trichodiene Synthase 19 2.75 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
1YYR Y305F Trichodiene Synthase: Complex With Mg, Pyrophosphate, And (4R)-7-Azabisabolene Trichodiene Synthase 19 2.5 Yes Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
1YJ4 Y305F Trichodiene Synthase Trichodiene Synthase 19 2.3 Yes 1,2-Ethanediol CSA • PDB • PDBSum
1YYU D100E Trichodiene Synthase: Complex With Mg, Pyrophosphate, And (4S)-7-Azabisabolene Trichodiene Synthase 19 2.95 Yes Magnesium Ion
(4 more ⇓)
CSA • PDB • PDBSum
1YYT D100E Trichodiene Synthase: Complex With Mg, Pyrophosphate, And (4R)-7-Azabisabolene Trichodiene Synthase 19 2.9 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2PS5 N225D Trichodiene Synthase: Complex With Mg And Pyrophosphate Trichodiene Synthase 19 2.1 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2PS4 N225D Trichodiene Synthase Trichodiene Synthase 19 2.46 Yes Magnesium Ion • 1,2-Ethanediol CSA • PDB • PDBSum
2PS6 N225D/S229T Trichodiene Synthase Trichodiene Synthase 18 2.6 Yes 1,2-Ethanediol CSA • PDB • PDBSum
2Q9Y Trichodiene Synthase: Complex With Mg, Inorganic Pyrophosphate, And Benzyl Triethyl Ammonium Cation Trichodiene Synthase 20 2.85 Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
2Q9Z Trichodiene Synthase: Complex With Inorganic Pyrophosphate Resulting From The Reaction With 2-Fluorofarnesyl Diphosphate Trichodiene Synthase 20 2.95 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
O81192 1N1B Crystal Structure Of (+)-Bornyl Diphosphate Synthase From Sage (+)-Bornyl Diphosphate Synthase 4 2.0 Magnesium Ion • Mercury (Ii) Ion CSA • PDB • PDBSum
1N1Z (+)-Bornyl Diphosphate Synthase: Complex With Mg And Pyrophosphate (+)-Bornyl Diphosphate Synthase 4 2.3 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
1N20 (+)-Bornyl Diphosphate Synthase: Complex With Mg And 3-Aza-2,3-Dihydrogeranyl Diphosphate (+)-Bornyl Diphosphate Synthase 4 2.3 Magnesium Ion • 2-[Methyl-(4-Methyl-Pent-3-Enyl)-Amino]-Ethyl-Diphosphate CSA • PDB • PDBSum
1N21 (+)-Bornyl Diphosphate Synthase: Cocrystal With Mg And 3-Aza-2,3-Dihydrogeranyl Diphosphate (+)-Bornyl Diphosphate Synthase 4 3.1 Magnesium Ion • 2-[Methyl-(4-Methyl-Pent-3-Enyl)-Amino]-Ethyl-Diphosphate CSA • PDB • PDBSum
1N22 (+)-Bornyl Diphosphate Synthase: Complex With Mg, Pyrophosphate, And (4R)-7-Aza-7,8-Dihydrolimonene (+)-Bornyl Diphosphate Synthase 4 2.4 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
1N23 (+)-Bornyl Diphosphate Synthase: Complex With Mg, Pyrophosphate, And (1R,4S)-2-Azabornane (+)-Bornyl Diphosphate Synthase 4 2.4 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
1N24 (+)-Bornyl Diphosphate Synthase: Complex With Mg And Product (+)-Bornyl Diphosphate Synthase 4 2.3 Magnesium Ion • (+)-Bornyl Diphosphate CSA • PDB • PDBSum
Q40322 2ONH Crystal Structure Of Of Limonene Synthase With 2-Fluorolinalyl Diphosphate(Flpp) 4S-Limonene Synthase 14 2.7 Yes Manganese (Ii) Ion
(2 more ⇓)
CSA • PDB • PDBSum
2ONG Crystal Structure Of Of Limonene Synthase With 2-Fluorogeranyl Diphosphate (Fgpp). 4S-Limonene Synthase 14 2.7 Yes Manganese (Ii) Ion
(2 more ⇓)
CSA • PDB • PDBSum
O81191 2J5C Rational Conversion Of Substrate And Product Specificity In A Monoterpene Synthase. Structural Insights Into The Molecular Basis Of Rapid Evolution. 1,8-Cineole Synthase 5 1.95 Beta-Mercaptoethanol CSA • PDB • PDBSum
O81086 3SAE Structure Of A Three-Domain Sesquiterpene Synthase: A Prospective Target For Advanced Biofuels Production Alpha-Bisabolene Synthase 6 1.96 Chloride Ion
(3 more ⇓)
CSA • PDB • PDBSum
3SDR Structure Of A Three-Domain Sesquiterpene Synthase: A Prospective Target For Advanced Biofuels Production Alpha-Bisabolene Synthase 6 1.86 Chloride Ion
(2 more ⇓)
CSA • PDB • PDBSum
3SDQ Structure Of A Three-Domain Sesquiterpene Synthase: A Prospective Target For Advanced Biofuels Production Alpha-Bisabolene Synthase 6 2.14 Chloride Ion • Glycerol CSA • PDB • PDBSum
3SDV Structure Of A Three-Domain Sesquiterpene Synthase: A Prospective Target For Advanced Biofuels Production Alpha-Bisabolene Synthase 6 2.2 Chloride Ion
(2 more ⇓)
CSA • PDB • PDBSum
3SDT Structure Of A Three-Domain Sesquiterpene Synthase: A Prospective Target For Advanced Biofuels Production Alpha-Bisabolene Synthase 6 1.89 Chloride Ion
(3 more ⇓)
CSA • PDB • PDBSum
3SDU Structure Of A Three-Domain Sesquiterpene Synthase: A Prospective Target For Advanced Biofuels Production Alpha-Bisabolene Synthase 6 1.89 Chloride Ion
(2 more ⇓)
CSA • PDB • PDBSum
Q9UR08 3BNY Crystal Structure Of Aristolochene Synthase Complexed With 2-Fluorofarnesyl Diphosphate (2F-Fpp) Aristolochene Synthase 1 1.89 Chloride Ion
(3 more ⇓)
CSA • PDB • PDBSum
2E4O X-Ray Crystal Structure Of Aristolochene Synthase From Aspergillus Terreus And The Evolution Of Templates For The Cyclization Of Farnesyl Diphosphate Aristolochene Synthase 1 2.2 Chloride Ion
(2 more ⇓)
CSA • PDB • PDBSum
2OA6 Aristolochene Synthase From Aspergillus Terreus Complexed With Pyrophosphate Aristolochene Synthase 1 2.15 Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
3CKE Crystal Structure Of Aristolochene Synthase In Complex With 12,13-Difluorofarnesyl Diphosphate Aristolochene Synthase 1 2.4 Chloride Ion
(5 more ⇓)
CSA • PDB • PDBSum
3BNX Crystal Structure Of Aristolochene Synthase Complexed With Farnesyl Diphosphate Aristolochene Synthase 1 2.1 Magnesium Ion
(4 more ⇓)
CSA • PDB • PDBSum
4KUX Crystal Structure Of Aspergillus Terreus Aristolochene Synthase Complexed With Farnesyl Thiolodiphosphate (Fspp) Aristolochene Synthase 1 1.9 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4KVY Crystal Structure Of Aspergillus Terreus Aristolochene Synthase Complexed With (1S,8S,9Ar)-1,9A-Dimethyl-8-(Prop-1-En-2-Yl) Decahydroquinolizin-5-Ium Aristolochene Synthase 1 1.95 Pyrophosphate 2-
(3 more ⇓)
CSA • PDB • PDBSum
4KVW Crystal Structure Of Aspergillus Terreus Aristolochene Synthase Complexed With (3R,6R,9Ar)-6,9A-Dimethyl-3-(Prop-1-En-2-Yl) Decahydroquinolizin-5-Ium Aristolochene Synthase 1 2.1 Pyrophosphate 2-
(3 more ⇓)
CSA • PDB • PDBSum
4KVI Crystal Structure Of Aspergillus Terreus Aristolochene Synthase Complexed With (4As,7S)-4A-Methyl-7-(Prop-1-En-2-Yl)-2,3,4,4A,5,6,7, 8-Octahydroquinolin-1-Ium Aristolochene Synthase 1 2.15 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4KWD Crystal Structure Of Aspergillus Terreus Aristolochene Synthase Complexed With (1R,8R,9As)-1,9A-Dimethyl-8-(Prop-1-En-2-Yl) Decahydroquinolizin-5-Ium Aristolochene Synthase 1 1.86 Pyrophosphate 2-
(3 more ⇓)
CSA • PDB • PDBSum
4KVD Crystal Structure Of Aspergillus Terreus Aristolochene Synthase Complexed With (4As,7S)-1,4A-Dimethyl-7-(Prop-1-En-2-Yl) Decahydroquinolin-1-Ium Aristolochene Synthase 1 2.4 Pyrophosphate 2-
(3 more ⇓)
CSA • PDB • PDBSum
P93665 3G4F Crystal Structure Of (+)- -Cadinene Synthase From Gossypium Arboreum In Complex With 2-Fluorofarnesyl Diphosphate (+)-Delta-Cadinene Synthase Isozyme Xc1 15 2.65 Beta-Mercaptoethanol
(2 more ⇓)
CSA • PDB • PDBSum
3G4D Crystal Structure Of (+)-Delta-Cadinene Synthase From Gossypium Arboreum And Evolutionary Divergence Of Metal Binding Motifs For Catalysis (+)-Delta-Cadinene Synthase Isozyme Xc1 15 2.4 Beta-Mercaptoethanol • Glycerol CSA • PDB • PDBSum
Q38710 3S9V Abietadiene Synthase From Abies Grandis Abietadiene Synthase, Chloroplastic 10 2.3 CSA • PDB • PDBSum
Q41594 3P5R Crystal Structure Of Taxadiene Synthase From Pacific Yew (Taxus Brevifolia) In Complex With Mg2+ And 2-Fluorogeranylgeranyl Diphosphate Taxadiene Synthase 24 2.25 Magnesium Ion • (2Z,6E,10E)-2-Fluoro-3,7,11,15-Tetramethylhexadeca-2,6, 10,14-Tetraen-1-Yl Trihydrogen Diphosphate CSA • PDB • PDBSum
3P5P Crystal Structure Of Taxadiene Synthase From Pacific Yew (Taxus Brevifolia) In Complex With Mg2+ And 13-Aza-13,14-Dihydrocopalyl Diphosphate Taxadiene Synthase 24 1.82 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
O66129 3AQC M. Luteus B-P 26 Heterodimeric Hexaprenyl Diphosphate Synthase In Complex With Magnesium And Fpp Analogue Component A Of Hexaprenyl Diphosphate Synthase • Component B Of Hexaprenyl Diphosphate Synthase 1 2.61 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
3AQB M. Luteus B-P 26 Heterodimeric Hexaprenyl Diphosphate Synthase In Complex With Magnesium Component A Of Hexaprenyl Diphosphate Synthase • Component B Of Hexaprenyl Diphosphate Synthase 1 2.4 Magnesium Ion • Chloride Ion CSA • PDB • PDBSum
P14324 1ZW5 X-Ray Structure Of Farnesyl Diphosphate Synthase Protein Farnesyl Diphosphate Synthase 24 2.3 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2OPM Human Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Bph-461 Farnesyl Pyrophosphate Synthetase (Fpp Synthetase) (Fps)(Farnesyl Diphosphate Synthetase) [Includes:Dimethylallyltranstransferase (Ec 2.5.1.1) • Geranyltranstransferase(Ec 2.5.1.10)] 24 2.4 Phosphate Ion
(2 more ⇓)
CSA • PDB • PDBSum
1YV5 Human Farnesyl Diphosphate Synthase Complexed With Mg And Risedronate Farnesyl Pyrophosphate Synthetase 24 2.0 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2OPN Human Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Bph-527 Farnesyl Pyrophosphate Synthetase (Fpp Synthetase) (Fps)(Farnesyl Diphosphate Synthetase) [Includes:Dimethylallyltranstransferase (Ec 2.5.1.1) • Geranyltranstransferase(Ec 2.5.1.10)] 24 2.7 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
1YQ7 Human Farnesyl Diphosphate Synthase Complexed With Risedronate Farnesyl Pyrophosphate Synthetase 24 2.2 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
3CP6 Crystal Structure Of Human Farnesyl Diphosphate Synthase (T201A Mutant) Complexed With Mg And Biphosphonate Inhibitor Farnesyl Pyrophosphate Synthetase 24 1.95 Yes Magnesium Ion • (4As,7Ar)-Octahydro-1H-Cyclopenta[B]Pyridine-6,6-Diylbis(Phosphonic Acid) CSA • PDB • PDBSum
3B7L Human Farnesyl Diphosphate Synthase Complexed With Mg And Minodronate Farnesyl Pyrophosphate Synthetase 24 1.95 Magnesium Ion • (1-Hydroxy-2-Imidazo[1,2-A]Pyridin-3-Ylethane-1,1-Diyl)Bis(Phosphonic Acid) CSA • PDB • PDBSum
2QIS Crystal Structure Of Human Farnesyl Pyrophosphate Synthase T210S Mutant Bound To Risedronate Farnesyl Pyrophosphate Synthetase 24 1.8 Yes Magnesium Ion • 1-Hydroxy-2-(3-Pyridinyl)Ethylidene Bis-Phosphonic Acid CSA • PDB • PDBSum
3N46 Human Fpps Complex With Nov_980 And Zoledronic Acid/Mg2+ Farnesyl Pyrophosphate Synthase 24 2.35 (2R)-1-[(Benzyloxy)Carbonyl]-2,3-Dihydro-1H-Indole-2-Carboxylic Acid
(3 more ⇓)
CSA • PDB • PDBSum
3N45 Human Fpps Complex With Fbs_04 And Zoledronic Acid/Mg2+ Farnesyl Pyrophosphate Synthase 24 1.88 (2S)-1-[(Benzyloxy)Carbonyl]-2,3-Dihydro-1H-Indole-2-Carboxylic Acid
(3 more ⇓)
CSA • PDB • PDBSum
2F89 Crystal Structure Of Human Fpps In Complex With Pamidronate Farnesyl Diphosphate Synthase 24 2.6 Phosphate Ion
(2 more ⇓)
CSA • PDB • PDBSum
2F8Z Crystal Structure Of Human Fpps In Complex With Zoledronate And Isopentenyl Diphosphate Farnesyl Diphosphate Synthase 24 2.6 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2F7M Crystal Structure Of Unliganded Human Fpps Farnesyl Diphosphate Synthase 24 2.3 Phosphate Ion CSA • PDB • PDBSum
3N3L Human Fpps Complex With Fbs_03 Farnesyl Pyrophosphate Synthase 24 2.74 (6-Methoxy-1-Benzofuran-3-Yl)Acetic Acid • Phosphate Ion CSA • PDB • PDBSum
2F94 Crystal Structure Of Human Fpps In Complex With Ibandronate Farnesyl Diphosphate Synthase 24 1.94 Zinc Ion
(2 more ⇓)
CSA • PDB • PDBSum
2F92 Crystal Structure Of Human Fpps In Complex With Alendronate Farnesyl Diphosphate Synthase 24 2.15 Zinc Ion
(2 more ⇓)
CSA • PDB • PDBSum
3N1V Human Fpps Complex With Fbs_01 Farnesyl Pyrophosphate Synthase 24 2.18 (5-Chloro-3-Methyl-1-Benzothiophen-2-Yl)Acetic Acid • Phosphate Ion CSA • PDB • PDBSum
3N1W Human Fpps Complex With Fbs_02 Farnesyl Pyrophosphate Synthase 24 2.56 (5-Chloro-1-Benzothiophen-3-Yl)Acetic Acid • Phosphate Ion CSA • PDB • PDBSum
2F9K Crystal Structure Of Human Fpps In Complex With Zoledronate And Zn2+ Farnesyl Diphosphate Synthase 24 2.06 Zinc Ion
(2 more ⇓)
CSA • PDB • PDBSum
3N49 Human Fpps Complex With Nov_292 Farnesyl Pyrophosphate Synthase 24 2.5 Naphtho[2,1-B]Thiophen-1-Ylacetic Acid • Phosphate Ion CSA • PDB • PDBSum
3N6K Human Fpps Complex With Nov_823 Farnesyl Pyrophosphate Synthase 24 2.25 1-(Carboxymethyl)-1H-Benzo[G]Indole-2-Carboxylic Acid • Phosphate Ion CSA • PDB • PDBSum
3N5H Human Fpps Complex With Nov_304 Farnesyl Pyrophosphate Synthase 24 2.2 3-(Carboxymethyl)-4,7-Dichloro-1H-Indole-2-Carboxylic Acid • Phosphate Ion CSA • PDB • PDBSum
3N5J Human Fpps Complex With Nov_311 Farnesyl Pyrophosphate Synthase 24 2.35 3-(Carboxymethyl)-5,7-Dichloro-1H-Indole-2-Carboxylic Acid • Phosphate Ion CSA • PDB • PDBSum
2F8C Crystal Structure Of Fpps In Complex With Zoledronate Farnesyl Diphosphate Synthase 24 2.2 Phosphate Ion
(2 more ⇓)
CSA • PDB • PDBSum
2VF6 Human Fdps Synthase In Complex With Minodronate Farnesyl Pyrophosphate Synthetase 24 2.1 (1-Hydroxy-2-Imidazo[1,2-A]Pyridin-3-Ylethane-1,1-Diyl)Bis(Phosphonic Acid) • Magnesium Ion CSA • PDB • PDBSum
2RAH Human Fdps Synthase In Complex With Novel Inhibitor Farnesyl Pyrophosphate Synthetase 24 2.0 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
3S4J Human Fdps Synthase In Complex With A Rigid Analog Of Risedronate Farnesyl Pyrophosphate Synthase 24 1.95 Yes 6,7-Dihydro-5H-Cyclopenta[B]Pyridine-6,6-Diylbis(Phosphonic Acid)
(2 more ⇓)
CSA • PDB • PDBSum
4DEM Crystal Structure Of Human Fpps In Complex With Ys_04_70 Farnesyl Pyrophosphate Synthase 24 1.85 [({4-[4-(Propan-2-Yloxy)Phenyl]Pyridin-2-Yl}Amino) Methanediyl]Bis(Phosphonic Acid) • Magnesium Ion CSA • PDB • PDBSum
3RYE Human Fdps Synthase In Complex With A N-Methyl Pyridinum Bisphosphonate Farnesyl Pyrophosphate Synthase 24 2.1 Yes 3-(2-Hydroxy-2,2-Diphosphonoethyl)-1-Methylpyridinium
(2 more ⇓)
CSA • PDB • PDBSum
4H5E Crystal Structure Of Human Fpps In Ternary Complex With Ys0470 And Isopentenyl Pyrophosphate Farnesyl Pyrophosphate Synthase 24 2.04 [({4-[4-(Propan-2-Yloxy)Phenyl]Pyridin-2-Yl}Amino) Methanediyl]Bis(Phosphonic Acid)
(2 more ⇓)
CSA • PDB • PDBSum
4H5D Crystal Structure Of Human Fpps In Ternary Complex With Ys0470 And Inorganic Pyrophosphate Farnesyl Pyrophosphate Synthase 24 2.02 [({4-[4-(Propan-2-Yloxy)Phenyl]Pyridin-2-Yl}Amino) Methanediyl]Bis(Phosphonic Acid)
(2 more ⇓)
CSA • PDB • PDBSum
4H5C Crystal Structure Of Human Fpps In Ternary Complex With Ys0470 And Inorganic Phosphate Farnesyl Pyrophosphate Synthase 24 2.02 [({4-[4-(Propan-2-Yloxy)Phenyl]Pyridin-2-Yl}Amino) Methanediyl]Bis(Phosphonic Acid)
(2 more ⇓)
CSA • PDB • PDBSum
4GA3 Crystal Structure Of Human Farnesyl Diphosphate Synthase In Complex With Bph-1260 Farnesyl Pyrophosphate Synthase 24 2.39 1-Butyl-3-(2-Hydroxy-2,2-Diphosphonoethyl)-1H-Imidazol-3-Ium
(2 more ⇓)
CSA • PDB • PDBSum
4L2X Crystal Structure Of Human Fpps In Complex With Magnesium, Cl02134, And Inorganic Pyrophosphate Farnesyl Pyrophosphate Synthase 24 2.55 ({[6-(4-Cyclopropylphenyl)Thieno[2,3-D]Pyrimidin-4-Yl]Amino}Methanediyl)Bis(Phosphonic Acid)
(2 more ⇓)
CSA • PDB • PDBSum
4JVJ Crystal Structure Of Human Fpps In Complex With Magnesium, Cl01131, And Sulfate Farnesyl Pyrophosphate Synthase 24 2.8 ({[6-(4-Methylphenyl)Thieno[2,3-D]Pyrimidin-4-Yl]Amino}Methanediyl)Bis(Phosphonic Acid)
(2 more ⇓)
CSA • PDB • PDBSum
4LFV Crystal Structure Of Human Fpps In Complex With Ys0470 And Two Molecules Of Inorganic Phosphate Farnesyl Pyrophosphate Synthase 24 2.0 [({4-[4-(Propan-2-Yloxy)Phenyl]Pyridin-2-Yl}Amino) Methanediyl]Bis(Phosphonic Acid)
(3 more ⇓)
CSA • PDB • PDBSum
4KFA Crystal Structure Of Human Farnesyl Pyrophosphate Synthase (T201A Mutant) Complexed With Mg And Zoledronate Farnesyl Pyrophosphate Synthase 24 1.98 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4KQ5 Crystal Structure Of Human Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed With Mg And Zoledronate Farnesyl Pyrophosphate Synthase 23 2.4 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4KPJ Crystal Structure Of Farnesyl Pyrophosphate Synthase (Y204A) Mutant Complexed With Mg, Pamidronate Farnesyl Pyrophosphate Synthase 23 1.95 Yes Pamidronate
(2 more ⇓)
CSA • PDB • PDBSum
4KPD Crystal Structure Of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed With Mg, Risedronate And Isopentenyl Pyrophosphate Farnesyl Pyrophosphate Synthase 23 1.96 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4KQS Crystal Structure Of Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed With Mg, Risedronate And Isopentenyl Pyrophosphate Farnesyl Pyrophosphate Synthase 23 1.97 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4KQU Crystal Structure Of Farnesyl Synthase Mutant (Y204A) Complexed With Mg, Alendronate And Isopentenyl Pyrophosphate Farnesyl Pyrophosphate Synthase 23 2.07 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4LPG Crystal Structure Of Human Fpps In Complex With Cl01131 Farnesyl Pyrophosphate Synthase 24 2.35 Phosphate Ion • ({[6-(4-Methylphenyl)Thieno[2,3-D]Pyrimidin-4-Yl]Amino}Methanediyl)Bis(Phosphonic Acid) CSA • PDB • PDBSum
4LPH Crystal Structure Of Human Fpps In Complex With Cl03093 Farnesyl Pyrophosphate Synthase 24 2.3 Phosphate Ion • ({[6-(4-Methylphenyl)Thieno[2,3-D]Pyrimidin-4-Yl]Amino}Methyl)Phosphonic Acid CSA • PDB • PDBSum
4P0V Crystal Structure Of Human Farnesyl Diphosphoate Synthase In Complex With Zoledronate And Taxodione Farnesyl Pyrophosphate Synthase 24 2.4 Zoledronic Acid
(2 more ⇓)
CSA • PDB • PDBSum
4P0W Human Farnesyl Diphosphate Synthase In Complex With Arenarone And Zoledronate Farnesyl Pyrophosphate Synthase 24 2.41 2-{[(1S,2R,4As,8Ar)-1,2,4A-Trimethyl-5-Methylidenedecahydronaphthalen-1-Yl]Methyl}Cyclohexa-2,5-Diene-1,4-Dione
(2 more ⇓)
CSA • PDB • PDBSum
4P0X Human Farnesyl Diphosphate Synthase In Complex With Taxodione Farnesyl Pyrophosphate Synthase 24 2.5 (5Beta)-11-Hydroxyabieta-7,9(11),13-Triene-6,12-Dione CSA • PDB • PDBSum
4N9U The Role Of Lysine 200 In The Human Farnesyl Pyrophosphate Synthase Catalytic Mechanism And The Mode Of Inhibition By The Nitrogen-Containing Bisphosphonates Farnesyl Pyrophosphate Synthase 23 2.11 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4NKF The Effects Of Lysine 200 And Phenylalanine 239 Farnesyl Pyrophosphate Synthase (Fpps) Mutations On The Catalytic Activity, Crystal Structure And Inhibition By Nitrogen Containing Bisphosphonates Farnesyl Pyrophosphate Synthase 23 2.0 Yes Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
4NKE The Effects Of Lysine 200 And Phenylalanine 239 Farnesyl Pyrophosphate Synthase (Fpps) Mutations On The Catalytic Activity, Crystal Structure And Inhibition By Nitrogen Containing Bisphosphonates Farnesyl Pyrophosphate Synthase 23 1.46 Yes Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
4NG6 The Effects Of Lysine 200 And Phenylalanine 239 Farnesyl Pyrophosphate Synthase (Fpps) Mutations On The Catalytic Activity, Crystal Structure And Inhibition By Nitrogen Containing Bisphosphonates Farnesyl Pyrophosphate Synthase 23 2.35 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4NUA The Effects Of Lysine 200 And Phenylalanine 239 Farnesyl Pyrophosphate Synthase (Fpps) Mutations On The Catalytic Activity, Crystal Structure And Inhibition By Nitrogen Containing Bisphosphonates Farnesyl Pyrophosphate Synthase 23 1.43 Yes 1-Hydroxy-2-(3-Pyridinyl)Ethylidene Bis-Phosphonic Acid
(3 more ⇓)
CSA • PDB • PDBSum
4OGU The Effects Of Lysine 200 And Phenylalanine 239 Farnesyl Pyrophosphate Synthase (Fpps) Mutations On The Catalytic Activity, Crystal Structure And Inhibition By Nitrogen Containing Bisphosphonates Farnesyl Pyrophosphate Synthase 23 2.1 Yes Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4N1Z Crystal Structure Of Human Farnesyl Diphosphate Synthase In Complex With Bph-1222 Farnesyl Pyrophosphate Synthase 24 2.35 Phosphate Ion
(2 more ⇓)
CSA • PDB • PDBSum
4QXS Crystal Structure Of Human Fpps In Complex With Wc01088 Farnesyl Pyrophosphate Synthase 24 1.9 Phosphate Ion
(2 more ⇓)
CSA • PDB • PDBSum
4Q23 The Role Of Threonine 201 And Tyrosine 204 In The Human Farnesyl Pyrophosphate Synthase Catalytic Mechanism And The Mode Of Inhibition By The Nitrogen-Containing Bisphosphonates Farnesyl Pyrophosphate Synthase 24 1.98 Yes 1-Hydroxy-2-(3-Pyridinyl)Ethylidene Bis-Phosphonic Acid
(2 more ⇓)
CSA • PDB • PDBSum
4PVX Crystal Structure Of Human Fpps In Complex With [({4-[4-(Cyclopropyloxy)Phenyl]Pyridin-2-Yl}Amino)Methanediyl]Bis(Phosphonic Acid) Farnesyl Pyrophosphate Synthase 24 2.18 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4PVY Crystal Structure Of Human Fpps In Complex With [({5-[4-(Propan-2-Yloxy)Phenyl]Pyridin-3-Yl}Amino)Methanediyl]Bis(Phosphonic Acid) Farnesyl Pyrophosphate Synthase 24 2.05 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
4RXA Crystal Structure Of Human Farnesyl Diphosphate Synthase In Complex With Bph-1358 Farnesyl Pyrophosphate Synthase 24 2.2 N,N'-Bis[3-(4,5-Dihydro-1H-Imidazol-2-Yl) Phenyl]Biphenyl-4,4'-Dicarboxamide • Phosphate Ion CSA • PDB • PDBSum
4QPF New Lower Bone Affinity Bisphosphonate Drug Design For Effective Use In Diseases Characterized By Abnormal Bone Resorption Farnesyl Pyrophosphate Synthase 24 1.59 [1-Fluoro-2-(Imidazo[1,2-A]Pyridin-3-Yl)Ethane-1,1-Diyl]Bis(Phosphonic Acid) • Magnesium Ion CSA • PDB • PDBSum
O95749 2Q80 Crystal Structure Of Human Geranylgeranyl Pyrophosphate Synthase Bound To Ggpp Geranylgeranyl Pyrophosphate Synthetase 23 2.7 Magnesium Ion • Geranylgeranyl Diphosphate CSA • PDB • PDBSum
Q9SWH9 4KK2 Crystal Structure Of A Chimeric Fpp/Gfpp Synthase (Target Efi-502313C) From Artemisia Spiciformis (1-72:Gi751454468,73-346:Gi75233326), Apo Structure Monoterpene Synthase Fds-5, Chloroplastic - Farnesyldiphosphate Synthase 1 Chimera 3 2.2 CSA • PDB • PDBSum
Q12051 2Z52 S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Bph-23 Geranylgeranyl Pyrophosphate Synthetase 7 2.13 Magnesium Ion • (1-Hydroxydodecane-1,1-Diyl)Bis(Phosphonic Acid) CSA • PDB • PDBSum
2Z50 S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Bph-28 Geranylgeranyl Pyrophosphate Synthetase 7 2.01 (1-Hydroxyheptane-1,1-Diyl)Bis(Phosphonic Acid) CSA • PDB • PDBSum
2DH4 Geranylgeranyl Pyrophosphate Synthase Ypl069C 7 1.98 Magnesium Ion CSA • PDB • PDBSum
2E8W S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Ipp Geranylgeranyl Pyrophosphate Synthetase 7 2.35 Magnesium Ion • 3-Methylbut-3-Enyl Trihydrogen Diphosphate CSA • PDB • PDBSum
2E8V S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Product Ggpp (P21) Geranylgeranyl Pyrophosphate Synthetase 7 1.8 Geranylgeranyl Diphosphate CSA • PDB • PDBSum
2E8U S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Ipp (P21) Geranylgeranyl Pyrophosphate Synthetase 7 2.08 Magnesium Ion • 3-Methylbut-3-Enyl Trihydrogen Diphosphate CSA • PDB • PDBSum
2E8T S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium, Fspp And Ipp Geranylgeranyl Pyrophosphate Synthetase 7 2.13 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2Z78 S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Bph-806 Geranylgeranyl Pyrophosphate Synthetase 7 2.1 3-(Decyloxy)-5-(3,5-Difluorophenyl)-1-(2,2-Diphosphonoethyl)Pyridinium CSA • PDB • PDBSum
2E8X S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Gpp Geranylgeranyl Pyrophosphate Synthetase 7 2.04 Magnesium Ion • Geranyl Diphosphate CSA • PDB • PDBSum
2Z4V S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Ggpp (Inhibitory Site) Geranylgeranyl Pyrophosphate Synthetase 7 1.86 Magnesium Ion • Geranylgeranyl Diphosphate CSA • PDB • PDBSum
2Z4W S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Bph-749 Geranylgeranyl Pyrophosphate Synthetase 7 2.45 Magnesium Ion • [(6E,11E)-2,6,12,16-Tetramethylheptadeca-2,6,11,15-Tetraene-9,9-Diyl]Bis(Phosphonic Acid) CSA • PDB • PDBSum
2Z4X S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Bph-252 (P21) Geranylgeranyl Pyrophosphate Synthetase 7 1.9 Magnesium Ion • (1-Hydroxynonane-1,1-Diyl)Bis(Phosphonic Acid) CSA • PDB • PDBSum
2Z4Y S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Bph-252 Geranylgeranyl Pyrophosphate Synthetase 7 2.1 Magnesium Ion • (1-Hydroxynonane-1,1-Diyl)Bis(Phosphonic Acid) CSA • PDB • PDBSum
2Z4Z S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Bph-Sc01 Geranylgeranyl Pyrophosphate Synthetase 7 2.09 Magnesium Ion • (6E,11E)-Heptadeca-6,11-Diene-9,9-Diylbis(Phosphonic Acid) CSA • PDB • PDBSum
2E94 S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Bph-364 Geranylgeranyl Pyrophosphate Synthetase 7 2.18 Magnesium Ion • 3-Biphenyl-3-Yl-1-(2-Hydroxy-2,2-Diphosphonoethyl) Pyridinium CSA • PDB • PDBSum
2E95 S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Bph-675 Geranylgeranyl Pyrophosphate Synthetase 7 2.2 Magnesium Ion • 1-Hydroxy-2-[3'-(Naphthalene-2-Sulfonylamino)-Biphenyl-3-Yl]Ethylidene-1,1-Bisphosphonic Acid CSA • PDB • PDBSum
2E90 S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium, Pyrophosphate And Fpp Geranylgeranyl Pyrophosphate Synthetase 7 2.55 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2E91 S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Bph-91 Geranylgeranyl Pyrophosphate Synthetase 7 2.14 Magnesium Ion • Zoledronic Acid CSA • PDB • PDBSum
2E92 S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium And Bph-261 Geranylgeranyl Pyrophosphate Synthetase 7 2.31 Magnesium Ion • (1-Hydroxy-2-Imidazo[1,2-A]Pyridin-3-Ylethane-1,1-Diyl)Bis(Phosphonic Acid) CSA • PDB • PDBSum
2E93 S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Bph-629 Geranylgeranyl Pyrophosphate Synthetase 7 2.12 [2-(3-Dibenzofuran-4-Yl-Phenyl)-1-Hydroxy-1-Phosphono-Ethyl]-Phosphonic Acid CSA • PDB • PDBSum
2ZEV S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Magnesium, Ipp And Bph-715 Geranylgeranyl Pyrophosphate Synthetase 7 2.23 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2ZEU S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Bph-715 Geranylgeranyl Pyrophosphate Synthetase 7 2.0 3-(Decyloxy)-1-(2,2-Diphosphonoethyl)Pyridinium CSA • PDB • PDBSum
2Z7I S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Inhibitor Bph-742 Geranylgeranyl Pyrophosphate Synthetase 7 2.1 Magnesium Ion • (2,2-Diphosphonoethyl)(Dodecyl)Dimethylphosphonium CSA • PDB • PDBSum
2Z7H S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase In Complex With Inhibitor Bph-210 Geranylgeranyl Pyrophosphate Synthetase 7 2.08 Magnesium Ion • {1-Hydroxy-3-[Methyl(4-Phenylbutyl)Amino]Propane-1,1-Diyl}Bis(Phosphonic Acid) CSA • PDB • PDBSum
Q9SBR3 3OAC Mint Deletion Mutant Of Heterotetrameric Geranyl Pyrophosphate Synthase In Complex With Ligands Geranyl Diphosphate Synthase Large Subunit • Geranyl Diphosphate Synthase Small Subunit 5 2.6 Yes 3-Methylbut-3-Enyl Trihydrogen Diphosphate
(2 more ⇓)
CSA • PDB • PDBSum
3OAB Mint Deletion Mutant Of Heterotetrameric Geranyl Pyrophosphate Synthase In Complex With Ligands Geranyl Diphosphate Synthase Large Subunit • Geranyl Diphosphate Synthase Small Subunit 5 2.3 Yes Pyrophosphate
(4 more ⇓)
CSA • PDB • PDBSum
3KRO Mint Heterotetrameric Geranyl Pyrophosphate Synthase In Complex With Magnesium, Ipp, And Dmaspp (Ii) Geranyl Diphosphate Synthase Large Subunit • Geranyl Diphosphate Synthase Small Subunit 8 1.95 3-Methylbut-3-Enyl Trihydrogen Diphosphate
(4 more ⇓)
CSA • PDB • PDBSum
3KRA Mint Heterotetrameric Geranyl Pyrophosphate Synthase In Complex With Magnesium Geranyl Diphosphate Synthase Large Subunit • Geranyl Diphosphate Synthase Small Subunit 8 1.9 Magnesium Ion • 1,2-Ethanediol CSA • PDB • PDBSum
3KRC Mint Heterotetrameric Geranyl Pyrophosphate Synthase In Complex With Ipp Geranyl Diphosphate Synthase Large Subunit • Geranyl Diphosphate Synthase Small Subunit 8 2.3 3-Methylbut-3-Enyl Trihydrogen Diphosphate • 1,2-Ethanediol CSA • PDB • PDBSum
3KRF Mint Heterotetrameric Geranyl Pyrophosphate Synthase In Complex With Magnesium, Ipp, And Dmaspp (I) Geranyl Diphosphate Synthase Large Subunit • Geranyl Diphosphate Synthase Small Subunit 8 2.2 Pyrophosphate
(4 more ⇓)
CSA • PDB • PDBSum
3KRP Mint Heterotetrameric Geranyl Pyrophosphate Synthase In Complex With Magnesium And Gpp Geranyl Diphosphate Synthase Large Subunit • Geranyl Diphosphate Synthase Small Subunit 8 2.42 Pyrophosphate
(3 more ⇓)
CSA • PDB • PDBSum
Q9RME5 4KKM Crystal Structure Of A Fpp/Gfpp Synthase (Target Efi-501952) From Zymomonas Mobilis, Apo Structure Polyprenyl Synthetase 3 1.9 Glycerol
(2 more ⇓)
CSA • PDB • PDBSum
Q9LAK9 3Q2Q Crystal Structure Of Geranylgeranyl Pyrophosphate Synthase From Corynebacterium Glutamicum Complexed With Calcium And Isoprenyl Diphosphate Geranylgeranyl Pyrophosphate Synthase 5 1.9 Dimethylallyl Diphosphate
(2 more ⇓)
CSA • PDB • PDBSum
3LMD Crystal Structure Of Geranylgeranyl Pyrophosphate Synthase From Corynebacterium Glutamicum Atcc 13032 Geranylgeranyl Pyrophosphate Synthase 5 1.9 CSA • PDB • PDBSum
Q9KWR7 3M0G Crystal Structure Of Putative Farnesyl Diphosphate Synthase From Rhodobacter Capsulatus Farnesyl Diphosphate Synthase 4 1.9 Selenomethionine CSA • PDB • PDBSum
Q5HZ00 3APZ Apo Form Of Arabidopsis Medium/Long-Chain Length Prenyl Pyrophosphate Synthase Geranyl Diphosphate Synthase 7 2.6 CSA • PDB • PDBSum
3AQ0 Ligand-Bound Form Of Arabidopsis Medium/Long-Chain Length Prenyl Pyrophosphate Synthase (Surface Polar Residue Mutant) Geranyl Diphosphate Synthase 7 2.65 Yes Magnesium Ion
(4 more ⇓)
CSA • PDB • PDBSum
O58799 1WY0 Crystal Structure Of Geranylgeranyl Pyrophosphate Synthetase From Pyrococcus Horikoshii Ot3 Geranylgeranyl Pyrophosphate Synthetase 1 2.2 Mercury (Ii) Ion • Bromide Ion CSA • PDB • PDBSum
A0A0C7CXR8
(7 more ⇓)
3ZCD Native Structure Of Farnesyl Pyrophosphate Synthase From Pseudomonas Aeruginosa Pa01. Geranyltranstransferase 7 1.55 CSA • PDB • PDBSum
3ZMB Native Structure Of Farnesyl Pyrophosphate Synthase From Pseudomonas Aeruginosa Pa01, With Bound Fragment Spb02696. Geranyltranstransferase 7 1.9 Chloride Ion
(2 more ⇓)
CSA • PDB • PDBSum
3ZMC Native Structure Of Farnesyl Pyrophosphate Synthase From Pseudomonas Aeruginosa Pa01, With Bound Substrate Molecule Geranyl Pyrophosphate. Geranyltranstransferase 7 1.87 Geranyl Diphosphate
(3 more ⇓)
CSA • PDB • PDBSum
3ZL6 Native Structure Of Farnesyl Pyrophosphate Synthase From Pseudomonas Aeruginosa Pao1, With Bound Fragment Km10833. Geranyltranstransferase 7 1.85 2-(1,2-Benzoxazol-3-Yl)Ethanoic Acid
(2 more ⇓)
CSA • PDB • PDBSum
3ZOU Native Structure Of Farnesyl Pyrophosphate Synthase From Pseudomonas Aeruginosa Pa01, With Bound Fragment Spb02696, And Substrate Geranyl Pyrophosphate. Farnesyl Pyrophosphate Synthase 7 1.55 Geranyl Diphosphate
(4 more ⇓)
CSA • PDB • PDBSum
4UMJ Native Structure Of Farnesyl Pyrophosphate Synthase From Pseudomonas Aeruginosa Pa01, With Bound Ibandronic Acid Molecules. Geranyltranstransferase 7 1.85 Ibandronate • Magnesium Ion CSA • PDB • PDBSum
Q9ZMJ4 3TC1 Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Helicobacter Pylori Octaprenyl Pyrophosphate Synthase 95 2.0 Magnesium Ion CSA • PDB • PDBSum
Q9WY08 R4NMX3 2FTZ Crystal Structure Of Geranyltranstransferase (Ec 2.5.1.10) (Tm0161) From Thermotoga Maritima At 1.90 A Resolution Geranyltranstransferase 4 1.9 N-Dimethyl-Lysine
(2 more ⇓)
CSA • PDB • PDBSum
A0A0F6ALU8
(2 more ⇓)
1V4E Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima Octoprenyl-Diphosphate Synthase 19 2.28 Sulfate Ion CSA • PDB • PDBSum
1WKZ Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima K41A Mutant Octoprenyl-Diphosphate Synthase 19 3.4 Yes Sulfate Ion CSA • PDB • PDBSum
1WL0 Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima R44A Mutant Octoprenyl-Diphosphate Synthase 19 3.2 Yes Sulfate Ion CSA • PDB • PDBSum
1WL1 Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima H74A Mutant Octoprenyl-Diphosphate Synthase 19 3.45 Yes CSA • PDB • PDBSum
1WL2 Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima R90A Mutant Octoprenyl-Diphosphate Synthase 19 2.8 Yes Sulfate Ion CSA • PDB • PDBSum
1WL3 Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima R91A Mutant Octoprenyl-Diphosphate Synthase 19 3.5 Yes CSA • PDB • PDBSum
1VG2 Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima A76Y Mutant Octoprenyl-Diphosphate Synthase 19 3.1 Yes CSA • PDB • PDBSum
1VG3 Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima A76Y/S77F Mutant Octoprenyl-Diphosphate Synthase 17 2.7 Yes Sulfate Ion CSA • PDB • PDBSum
1VG4 Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A/L128A Mutant Octoprenyl-Diphosphate Synthase 17 3.3 Yes CSA • PDB • PDBSum
1VG6 Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A/L128A/I123A Mutant Octoprenyl-Diphosphate Synthase 17 3.35 Yes CSA • PDB • PDBSum
1VG7 Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A/L128A/I123A/D62A Mutant Octoprenyl-Diphosphate Synthase 17 3.4 Yes CSA • PDB • PDBSum
1V4H Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F52A Mutant Octoprenyl-Diphosphate Synthase 19 2.8 Yes Sulfate Ion CSA • PDB • PDBSum
1V4I Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima F132A Mutant Octoprenyl-Diphosphate Synthase 19 2.4 Yes Sulfate Ion CSA • PDB • PDBSum
1V4J Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima V73Y Mutant Octoprenyl-Diphosphate Synthase 19 2.85 Yes Sulfate Ion CSA • PDB • PDBSum
1V4K Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima S77F Mutant Octoprenyl-Diphosphate Synthase 19 2.45 Yes Sulfate Ion CSA • PDB • PDBSum
2AZL Crystal Structure For The Mutant F117E Of Thermotoga Maritima Octaprenyl Pyrophosphate Synthase Octoprenyl-Diphosphate Synthase 19 2.8 Yes CSA • PDB • PDBSum
O25583 3LLW Crystal Structure Of Geranyltransferase From Helicobacter Pylori 26695 Geranyltranstransferase (Ispa) 53 2.3 Sulfate Ion CSA • PDB • PDBSum
3Q1O Crystal Structure Of Geranyltransferase From Helicobacter Pylori Complexed With Magnesium And Isoprenyl Diphosphate Geranyltranstransferase (Ispa) 59 2.4 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
A0A0F6BZV3
(6 more ⇓)
1RQJ Active Conformation Of Farnesyl Pyrophosphate Synthase Bound To Isopentyl Pyrophosphate And Risedronate Geranyltranstransferase 44 1.95 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
1RQI Active Conformation Of Farnesyl Pyrophosphate Synthase Bound To Isopentyl Pyrophosphate And Dimethylallyl S-Thiolodiphosphate Geranyltranstransferase 44 2.42 Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
2FOR Crystal Structure Of The Shigella Flexneri Farnesyl Pyrophosphate Synthase Complex With An Isopentenyl Pyrophosphate Geranyltranstransferase 43 2.0 Phosphate Ion • Isopentyl Pyrophosphate CSA • PDB • PDBSum
A0A0F6C9F7
(5 more ⇓)
3WJN Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Escherichia Coli With Farnesyl S-Thiol-Pyrophosphate (Fspp) Octaprenyl Diphosphate Synthase 67 2.6 S-[(2E,6E)-3,7,11-Trimethyldodeca-2,6,10-Trienyl] Trihydrogen Thiodiphosphate CSA • PDB • PDBSum
3WJO Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Escherichia Coli With Isopentenyl Pyrophosphate (Ipp) Octaprenyl Diphosphate Synthase 67 2.45 3-Methylbut-3-Enyl Trihydrogen Diphosphate CSA • PDB • PDBSum
3WJK Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Escherichia Coli Octaprenyl Diphosphate Synthase 67 2.2 CSA • PDB • PDBSum
A0A083ZHC2 Q7CWE5 2H8O The 1.6A Crystal Structure Of The Geranyltransferase From Agrobacterium Tumefaciens Geranyltranstransferase 3 1.6 CSA • PDB • PDBSum
Q97W92
(2 more ⇓)
2AZJ Crystal Structure For The Mutant D81C Of Sulfolobus Solfataricus Hexaprenyl Pyrophosphate Synthase Geranylgeranyl Pyrophosphate Synthetase 6 2.4 Yes CSA • PDB • PDBSum
2AZK Crystal Structure For The Mutant W136E Of Sulfolobus Solfataricus Hexaprenyl Pyrophosphate Synthase Geranylgeranyl Pyrophosphate Synthetase 6 2.7 Yes CSA • PDB • PDBSum
A0A0H3JL30
(2 more ⇓)
1RTR Crystal Structure Of S. Aureus Farnesyl Pyrophosphate Synthase Geranyltranstransferase 23 2.5 CSA • PDB • PDBSum
Q9A6I1 3OYR Crystal Structure Of Polyprenyl Synthase From Caulobacter Crescentus Cb15 Complexed With Calcium And Isoprenyl Diphosphate Trans-Isoprenyl Diphosphate Synthase 4 2.0 Pyrophosphate 2-
(2 more ⇓)
CSA • PDB • PDBSum
Q8XJE0 3UCA Crystal Structure Of Isoprenoid Synthase (Target Efi-501974) From Clostridium Perfringens Geranyltranstransferase 8 2.0 CSA • PDB • PDBSum
Q8WS25 1YHK Trypanosoma Cruzi Farnesyl Diphosphate Synthase Farnesyl Pyrophosphate Synthase 18 2.1 Sulfate Ion CSA • PDB • PDBSum
1YHL Structure Of The Complex Of Trypanosoma Cruzi Farnesyl Diphosphate Synthase With Risedronate, Dmapp And Mg+2 Farnesyl Pyrophosphate Synthase 18 1.95 Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
3IBA Crystal Structure Of The Complex Of Trypanosoma Cruzi Farnesyl Diphosphate Synthase With Zoledronate, Ipp And Mg2+ Farnesyl Pyrophosphate Synthase 18 2.4 Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
3ICZ Trypanosoma Cruzi Farnesyl Diphosphate Synthase Homodimer In Complex With 1-(2,2-Bis-Phosphono-Ethyl)-3-Butyl-Pyridinium And Isopentenyl Pyrophosphate Farnesyl Pyrophosphate Synthase 18 2.15 3-Methylbut-3-Enyl Trihydrogen Diphosphate
(2 more ⇓)
CSA • PDB • PDBSum
3ID0 Trypanosoma Cruzi Farnesyl Diphosphate Synthase Homodimer In Complex With 3-Fluoro-1-(2-Hydroxy-2,2-Bisphosphono-Ethyl) Pyridinium Farnesyl Pyrophosphate Synthase 18 2.81 3-Fluoro-1-(2-Hydroxy-2,2-Diphosphonoethyl)Pyridinium
(2 more ⇓)
CSA • PDB • PDBSum
3ICM Trypanosoma Cruzi Farnesyl Diphosphate Synthase Homodimer In Complex With Isopentenyl Pyrophosphate, Mg2+ And 1-(2-Hydroxy-2,2-Bis-Phosphono-Ethyl)-3-Phenyl-Pyridinium Farnesyl Pyrophosphate Synthase 18 2.2 1-(2-Hydroxy-2,2-Diphosphonoethyl)-3-Phenylpyridinium
(3 more ⇓)
CSA • PDB • PDBSum
3ICN Trypanosoma Cruzi Farnesyl Diphosphate Synthase Homodimer In Complex With Isopentenyl Pyrophosphate And 3-Fluoro-1-(2-Hydroxy-2,2-Bis-Phosphono-Ethyl)-Pyridinium Farnesyl Pyrophosphate Synthase 18 2.4 3-Fluoro-1-(2-Hydroxy-2,2-Diphosphonoethyl)Pyridinium
(3 more ⇓)
CSA • PDB • PDBSum
3ICK Trypanosoma Cruzi Farnesyl Diphosphate Synthase Homodimer In Complex With Minodronate And Isopentenyl Disphosphate Farnesyl Pyrophosphate Synthase 18 2.4 Acetic Acid
(4 more ⇓)
CSA • PDB • PDBSum
1YHM Structure Of The Complex Of Trypanosoma Cruzi Farnesyl Disphosphate Synthase With Alendronate, Isopentenyl Diphosphate And Mg+2 Farnesyl Pyrophosphate Synthase 8 2.5 Selenomethionine
(4 more ⇓)
CSA • PDB • PDBSum
4DWB Crystal Structure Of Trypanosoma Cruzi Farnesyl Diphosphate Synthase In Complex With [2-(N-Pentylamino)Ethane-1,1-Diyl]Bisphosphonic Acid And Mg2+ Farnesyl Pyrophosphate Synthase 18 2.1 3-Methylbut-3-Enyl Trihydrogen Diphosphate
(5 more ⇓)
CSA • PDB • PDBSum
4DWG Crystal Structure Of Trypanosome Cruzi Farnesyl Diphosphate Synthase In Complex With [2-(N-Heptylamino)Ethane-1,1-Diyl]Bisphosphonic Acid And Mg2+ Farnesyl Pyrophosphate Synthase 18 2.01 Magnesium Ion
(5 more ⇓)
CSA • PDB • PDBSum
4DZW Crystal Structure Of Trypanosome Cruzi Farnesyl Diphosphate Synthase In Complex With [2-(Cyclohexylamino)Ethane-1,1-Diyl]Bisphosphonic Acid And Mg2+ Farnesyl Pyrophosphate Synthase 18 3.05 N-Formylmethionine
(4 more ⇓)
CSA • PDB • PDBSum
4E1E Crystal Structure Of Trypanosome Cruzi Farnesyl Diphosphate Synthase In Complex With [2-(N-Hexylamino)Ethane-1,1-Diyl]Bisphosphonic Acid And Mg2+ Farnesyl Pyrophosphate Synthase 18 2.65 Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
4DXJ Crystal Structure Of Trypanosome Cruzi Farnesyl Diphosphate Synthase In Complex With [2-(N-Propylamino)Ethane-1,1-Diyl]Bisphosphonic Acid And Mg2+ Farnesyl Pyrophosphate Synthase 18 2.35 Magnesium Ion
(6 more ⇓)
CSA • PDB • PDBSum
Q9X7V8 3NF2 Crystal Structure Of Polyprenyl Synthetase From Streptomyces Coelicolor A3(2) Putative Polyprenyl Synthetase 6 2.2 Sulfate Ion CSA • PDB • PDBSum
Q8PYS1 3IPI Crystal Structure Of A Geranyltranstransferase From The Methanosarcina Mazei Geranyltranstransferase 2 1.9 Selenomethionine • Malonic Acid CSA • PDB • PDBSum
Q8NNM1 3QQV Crystal Structure Of Geranylgeranyl Pyrophosphate Synthase From Corynebacterium Glutamicum Complexed With Isoprenyl Diphosphate And Magnesium Geranylgeranyl Pyrophosphate Synthase 6 2.0 Selenomethionine
(4 more ⇓)
CSA • PDB • PDBSum
3LK5 Crystal Structure Of Putative Geranylgeranyl Pyrophosphate Synthase From Corynebacterium Glutamicum Geranylgeranyl Pyrophosphate Synthase 6 1.9 Selenomethionine • Glycerol CSA • PDB • PDBSum
A0A0N7IB31 Q8A2P4 3RMG Crystal Structure Of Geranylgeranyl Pyrophosphate Synthase From Bacteroides Thetaiotaomicron Octaprenyl-Diphosphate Synthase 4 2.3 CSA • PDB • PDBSum
A0A1S9L725 Q836W4 3P8L Crystal Structure Of Polyprenyl Synthase From Enterococcus Faecalis V583 Geranyltranstransferase 14 2.0 CSA • PDB • PDBSum
Q72G62 1WMW Crystal Structure Of Geranulgeranyl Diphosphate Synthase From Thermus Thermophilus Geranylgeranyl Diphosphate Synthetase 5 1.55 CSA • PDB • PDBSum
Q6QLV2 3QKC Crystal Structure Of Geranyl Diphosphate Synthase Small Subunit From Antirrhinum Majus Geranyl Diphosphate Synthase Small Subunit 2 2.2 CSA • PDB • PDBSum
G8UTY8 Q5ZT35 3LOM Crystal Structure Of Geranyltransferase From Legionella Pneumophila Geranyltranstransferase 8 2.3 Phosphate Ion CSA • PDB • PDBSum
Q60AN0 3TS7 Crystal Structure Of Farnesyl Diphosphate Synthase (Target Efi-501951) From Methylococcus Capsulatus Geranyltranstransferase 2 1.94 Phosphate Ion CSA • PDB • PDBSum
farnesyl pyrophosphate synthase (no accession IDs) 3NPK The Crystal Structure Of Geranyltranstransferase From Campylobacter Jejuni Geranyltranstransferase 16 1.5 Selenomethionine
(2 more ⇓)
CSA • PDB • PDBSum
Q3KRM3 4LLS Crystal Structure Of A Farnesyl Diphosphate Synthase From Roseobacter Denitrificans Och 114, Target Efi-509393, With Ipp, Gspp, And Calcium Bound In Active Site Geranyltranstransferase 3 1.5 3-Methylbut-3-Enyl Trihydrogen Diphosphate
(2 more ⇓)
CSA • PDB • PDBSum
4LLT Crystal Structure Of A Farnesyl Diphosphate Synthase From Roseobacter Denitrificans Och 114, Target Efi-509393, With Two Ipp And Calcium Bound In Active Site Geranyltranstransferase 3 1.55 3-Methylbut-3-Enyl Trihydrogen Diphosphate • Calcium Ion CSA • PDB • PDBSum
Q5CR09 2Q58 Cryptosporidium Parvum Putative Polyprenyl Pyrophosphate Synthase (Cgd4_2550) In Complex With Zoledronate Farnesyl Pyrophosphate Synthase 3 2.37 Magnesium Ion • Zoledronic Acid CSA • PDB • PDBSum
2O1O Cryptosporidium Parvum Putative Polyprenyl Pyrophosphate Synthase (Cgd4_2550) In Complex With Risedronate. Putative Farnesyl Pyrophosphate Synthase 3 2.42 Magnesium Ion • 1-Hydroxy-2-(3-Pyridinyl)Ethylidene Bis-Phosphonic Acid CSA • PDB • PDBSum
Q4K5A6 3P41 Crystal Structure Of Polyprenyl Synthetase From Pseudomonas Fluorescens Pf-5 Complexed With Magnesium And Isoprenyl Pyrophosphate Geranyltranstransferase 3 1.76 Selenomethionine
(6 more ⇓)
CSA • PDB • PDBSum
3LJI Crystal Structure Of Putative Geranyltranstransferase From Pseudomonas Fluorescens Pf-5 Geranyltranstransferase 3 1.39 Selenomethionine CSA • PDB • PDBSum
3LSN Crystal Structure Of Putative Geranyltranstransferase From Pseudomonas Fluorescens Pf-5 Complexed With Magnesium Geranyltranstransferase 3 1.35 Selenomethionine • Magnesium Ion CSA • PDB • PDBSum
A0A1G4I956 Q57WF1 3EFQ T. Brucei Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Bph-714 Farnesyl Pyrophosphate Synthase 5 2.0 Magnesium Ion • 1-(2,2-Diphosphonoethyl)-3-(Octyloxy)Pyridinium CSA • PDB • PDBSum
2OGD T. Brucei Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Bph-527 Farnesyl Pyrophosphate Synthase 5 2.0 Acetate Ion
(4 more ⇓)
CSA • PDB • PDBSum
3DYH T. Brucei Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Bph-721 Farnesyl Pyrophosphate Synthase 5 1.94 Magnesium Ion • 3-Butoxy-1-(2,2-Diphosphonoethyl)Pyridinium CSA • PDB • PDBSum
3DYF T. Brucei Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Bph-461 And Isopentyl Diphosphate Farnesyl Pyrophosphate Synthase 5 2.65 Magnesium Ion
(5 more ⇓)
CSA • PDB • PDBSum
2EWG T. Brucei Farnesyl Diphosphate Synthase Complexed With Minodronate Farnesyl Pyrophosphate Synthase 5 2.48 Magnesium Ion
(2 more ⇓)
CSA • PDB • PDBSum
2P1C T. Brucei Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Bph-210 Farnesyl Pyrophosphate Synthase 5 2.45 Magnesium Ion
(3 more ⇓)
CSA • PDB • PDBSum
3DYG T. Brucei Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Bph-461 Farnesyl Pyrophosphate Synthase 5 2.1 Magnesium Ion
(4 more ⇓)
CSA • PDB • PDBSum
2I19 T. Brucei Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Farnesyl Pyrophosphate Synthase 5 2.28 Magnesium Ion • [2-(Pyridin-2-Ylamino)Ethane-1,1-Diyl]Bis(Phosphonic Acid) CSA • PDB • PDBSum
3EGT T. Brucei Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Bph-722 Farnesyl Pyrophosphate Synthase 5 2.0 Magnesium Ion • 1-(2,2-Diphosphonoethyl)-3-(Heptyloxy)Pyridinium CSA • PDB • PDBSum
4RYP Crystal Structure Of T. Brucei Farnesyl Diphosphate Synthase Farnesyl Pyrophosphate Synthase 5 2.21 CSA • PDB • PDBSum
4RXC T. Brucei Farnesyl Diphosphate Synthase Complexed With Homorisedronate Bph-6 Farnesyl Pyrophosphate Synthase 5 2.31 [1-Hydroxy-3-(Pyridin-3-Yl)Propane-1,1-Diyl]Bis(Phosphonic Acid) • Magnesium Ion CSA • PDB • PDBSum
4RXD T. Brucei Farnesyl Diphosphate Synthase Complexed With Risedronate Farnesyl Pyrophosphate Synthase 5 2.0 Magnesium Ion • 1-Hydroxy-2-(3-Pyridinyl)Ethylidene Bis-Phosphonic Acid CSA • PDB • PDBSum
4RXE T. Brucei Farnesyl Diphosphate Synthase Complexed With Bisphosphonate Bph-14 Farnesyl Pyrophosphate Synthase 5 2.5 {[(3-Methylpyridin-2-Yl) Amino]Methanediyl}Bis(Phosphonic Acid) • Magnesium Ion CSA • PDB • PDBSum
Percent identity and alignment length from the BLAST match of the Functional Domain sequence to the PDB sequence.
"Yes" indicates that a GI associated with this Functional Domain was mapped to the PDB ID via UniProtKB.
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