List of all Reactions

A four digit code that defines the overall chemical transformation performed by the enzyme.
The domain that is responsible for the function of the enzyme.
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Reactions on SFLD

# Reaction Name Reaction Type EC Number Directionality Substrates Products Schemes Functional
Domains
1 o-succinylbenzoate synthase cognate 4.2.1.113 reversible 1 2 1 1
2 methylaspartate ammonia-lyase cognate 4.3.1.2 reversible 1 2 1 1
3 gluconate dehydratase cognate 4.2.1.39 reversible 1 2 1 1
4 glucarate dehydratase cognate 4.2.1.40 reversible 1 2 1 2
5 L-rhamnonate dehydratase cognate 4.2.1.90 reversible 1 2 1 2
6 galactonate dehydratase cognate 4.2.1.6 reversible 1 2 1 1
7 mandelate racemase cognate 5.1.2.2 reversible 1 1 1 1
8 mannonate dehydratase cognate 4.2.1.8 reversible 1 2 2 3
9 phosphopyruvate hydratase cognate 4.2.1.11 reversible 1 2 1 1
10 3-chloromuconate cycloisomerase (non-dehalogenating) cognate 5.5.1.7 reversible 1 2 1 2
11 muconate cycloisomerase cognate 5.5.1.1 reversible 2 1 2 13
12 L-Ala-D/L-Glu epimerase cognate 5.1.1.20 reversible 1 1 1 1
13 N-acylamino acid racemase cognate 5.1.1.- reversible 1 1 1 1
14 dodecenoyl-CoA isomerase cognate reversible 1 1 4 4
15 crotonobetainyl-CoA hydratase cognate reversible 1 2 1 1
16 delta 3,5,delta 2,4-dienoyl-CoA isomerase cognate reversible 1 1 1 1
17 2-ketocyclohexanecarboxyl-CoA hydrolase cognate reversible 2 1 1 1
24 4-chlorobenzoyl-CoA dehalogenase cognate reversible 2 3 1 1
28 acireductone synthase cognate reversible 2 2 1 1
31 2-deoxyglucose-6-phosphatase cognate reversible 2 2 1 4
32 cis-3-Hydroxy-L-proline dehydratase cognate 4.2.1.- forward 1 2 1 3
35 glycerol-1-phosphatase cognate reversible 2 2 1 8
38 mannosyl-3-phosphoglycerate phosphatase cognate reversible 2 2 1 1
39 lipid-phosphate phosphatase cognate reversible 2 2 1 1
41 (S)-2-haloacid dehalogenase (configuration-inverting) generic 3.8.1.2 reversible 2 2 1 5
42 beta-phosphoglucomutase cognate 5.4.2.6 reversible 1 1 1 1
43 histidinol-phosphatase cognate reversible 2 2 1 1
44 biotin synthase cognate reversible 4 5 1 1
45 methylornithine synthase cognate reversible 1 1 1 1
46 2-iminoacetate synthase cognate reversible 3 5 1 1
47 3-methyl-2-indolic acid synthase cognate reversible 2 4 1 2
48 HydG cognate reversible 3 5 1 2
51 polynucleotide 5'-hydroxyl-kinase generic reversible 2 2 1 1
53 haloacetate dehalogenase generic reversible 2 3 1 1
57 3-deoxy-manno-octulosonate-8-phosphatase cognate reversible 2 2 1 6
64 melamine hydrolase cognate reversible 2 2 1 1
65 ammeline hydrolase cognate reversible 3 2 1 1
66 atrazine chlorohydrolase cognate reversible 2 3 1 1
67 hydroxydechloroatrazine ethylaminohydrolase cognate reversible 3 2 1 1
68 8-oxoguanine deaminase cognate reversible 3 2 1 1
87 xylonate dehydratase cognate 4.2.1.82 unknown 1 2 1 2
202 lipoyl synthase cognate 2.8.1.8 reversible 4 5 1 1
203 23S rRNA (adenine2503-C2)-methyltransferase cognate 2.1.1.192 reversible 3 5 1 1
204 coproporphyrinogen dehydrogenase cognate 1.3.99.22 reversible 2 4 1 6
205 tRNA 4-demethylwyosine synthase (AdoMet-dependent) cognate 4.1.3.44 reversible 3 5 1 1
206 Ser-type sulfatase maturase cognate 1.1.99.- reversible 2 3 1 1
207 Cys-type sulfatase maturase cognate 1.1.99.- reversible 3 4 1 1
208 Tyr-Glu cyclase cognate 5.-.-.- reversible 2 4 1 1
209 lysine 2,3-aminomutase cognate 5.4.3.2 reversible 1 1 2 2
210 glutamate 2,3-aminomutase cognate 5.4.3.9 reversible 1 1 1 1
211 arginine 2,3-aminomutase cognate 5.4.3.- reversible 1 1 1 1
212 spore photoproduct lyase cognate 4.1.99.14 reversible 1 1 2 2
213 CofH cognate 2.5.1.- reversible 3 4 1 1
214 CofG cognate 5.-.-.- reversible 2 3 1 2
215 [ribosomal protein S12] (aspartate89-C3)-methylthiotransferase cognate 2.8.4.4 reversible 3 4 1 1
216 tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase cognate 2.8.4.5 reversible 3 4 1 1
217 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase cognate 2.8.4.3 reversible 4 7 1 1
218 23S rRNA (adenine2503-C8)-methyltransferase cognate 2.1.1.224 reversible 3 5 1 1
219 [formate-C-acetyltransferase]-activating enzyme cognate 1.97.1.4 reversible 3 4 1 1
221 7-carboxy-7-deazaguanine synthase cognate 4.3.99.3 reversible 2 2 2 2
222 [4-hydroxyphenylacetate decarboxylase]-activating enzyme cognate 1.97.1.- reversible 3 4 1 1
223 cyclic pyranopterin phosphate synthase cognate 4.1.99.18 reversible 1 2 1 1
225 cyclic dehypoxanthinyl futalosine synthase cognate 1.21.98.1 reversible 2 4 1 1
231 anaerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase cognate 1.14.13.- reversible 3 3 1 1
232 avilamycin A epimerase cognate 5.1.3.- reversible 2 3 1 1
236 L-lyxonate dehydratase cognate 4.2.1.- unknown 1 2 1 4
238 nosiheptide methyltransferase cognate 2.1.1.- reversible 2 4 1 1
241 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) cognate 1.1.99.38 reversible 2 4 1 1
242 UDP-N-acetyl-tunicamine-uracil synthase cognate 4.-.-.- reversible 2 1 1 1
243 oxsB cognate 5.-.-.- reversible 1 1 1 1
244 dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase cognate 4.3.1.30 reversible 3 6 1 1
261 hop-22(29)-ene C2-methyltransferase cognate reversible 2 4 1 1
262 galactarate dehydratase 2/3 cognate 4.2.1.- forward 1 2 2 4
263 galactarolactone cycloisomerase cognate 5.5.1.- unknown 1 1 1 1
264 bacteriochlorophyll C8 methyltransferase generic reversible 2 4 1 1
265 bacteriochlorophyll C12 methyltransferase generic reversible 2 4 1 1
266 P-methyltransferase cognate 2.1.1.- reversible 2 4 1 1
267 thioether cross-link between Cys and Asp cognate forward 2 1 1 1
268 adenosyl-hopene transferase cognate 2.5.1.- reversible 2 3 1 2
270 gentamicin N-methyltransferase cognate reversible 2 4 1 1
272 TDP-rhammose dehydrogenase cognate reversible 2 4 1 1
273 fortimicin KL1 methyltransferase cognate reversible 2 4 1 1
274 gentamicin C6 methyltransferase cognate reversible 2 4 1 1
275 aminobacteriohopanepentol C3-methyltransferase cognate reversible 2 4 1 1
276 aminobacteriohopanetetrol C3-methyltransferase cognate 2.1.1.- reversible 2 4 1 1
277 3-methyl-2-indolic acid methyltransferase cognate reversible 2 4 1 2
281 [glycerol dehydratase]-activating enzyme cognate reversible 3 4 1 1
282 [benzylsuccinate synthase]-activating enzyme cognate reversible 3 4 1 1
283 [anaerobic ribonucleoside-triphosphate reductase]-activating protein cognate reversible 3 4 1 1
284 valine cyclopropanase cognate reversible 2 3 1 1
285 glutamate racemase cognate reversible 1 1 1 1
294 tryptophan 2-C-methyltransferase cognate reversible 2 4 1 1
295 yatakemycin methyltransferase cognate reversible 2 4 1 1
340 squalene synthase (NADP) cognate 2.5.1.21 reversible 3 3
367 aminodeoxyfutalosine synthase cognate reversible 3 4 1 1
371 2,4-dichloromuconate cycloisomerase cognate 5.5.1.11 unknown 1 2 1 1
372 2-chloromuconate cycloisomerase (dehalogenating) cognate 5.5.1.- unknown 1 2 1 4
373 3-methylmuconate cycloisomerase cognate 5.5.1.- unknown 1 1 1 2
374 3-chloromuconate cycloisomerase (dehalogenating, to protoanemonin) cognate 5.5.1.- forward 1 3 1 1
375 3-chloromuconate cycloisomerase (dehalogenating, to dienelactone) cognate 5.5.1.- forward 1 2 1 1
377 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase cognate 3.1.3.87 reversible 2 2 1 1
378 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase cognate 3.1.3.- reversible 2 2 1 5
379 glucose-1-phosphatase cognate 3.1.3.10 reversible 2 2 1 2
380 FMN phosphatase cognate 3.1.3.2 reversible 2 2 1 2
381 D-glycero-D-manno-heptose-1,7-bisphosphate 7-phosphatase cognate 3.1.3.- reversible 2 2 1 11
383 HMP-PP phosphatase unknown 3.1.3.- unknown 2 2 1 3
384 kanosamine-6-phosphate phosphatase cognate 3.1.3.92 reversible 2 2 1 3
385 mannosylfructose-phosphate phosphatase cognate 3.1.3.79 reversible 2 2 1 1
386 N-acylneuraminate-9-phosphatase cognate 3.1.3.29 reversible 2 2 1 3
387 C-terminal tyrosine decarboxylase cognate reversible 1 2 1 1
388 cytosylglucuronate decarboxylase cognate reversible 2 4 1 1
389 bacteriohopanetetrol cyclitol ether synthase cognate reversible 2 3 1 1
390 trans-but-2-enoyl-[ACP] cycloisomerase cognate reversible 2 3 1 1
391 didecarboxysirohaem deacetylase cognate reversible 2 4 1 1
392 Fe-coproporphyrin III decarboxylase cognate reversible 2 4 1 1
393 neomycin C epimerase cognate reversible 2 3 1 1
394 thioether cross-link between Cys and Thr cognate reversible 3 3 4 4
395 thioether cross-link between Cys and Phe cognate reversible 3 3 1 1
396 carbapenem intermediate methyltransferase, second methyltransferase cognate reversible 2 4 1 1
397 carbapenem intermediate methyltransferase, first methyltransferase cognate reversible 2 4 1 1
398 thioether cross-link between Cys and Glu cognate forward 3 3 1 1
399 thioether cross-link between Cys and Met cognate reversible 3 3 1 1
400 thioether cross-link between Cys and Ser cognate forward 3 3 2 2
401 thioether cross-link between Cys and Ala cognate forward 3 3 1 1
402 thioether cross-link between Cys and Asn cognate forward 3 3 1 1
403 thioether cross-link between Cys and Tyr cognate forward 3 3 1 1
404 Methylation of tallysomycin cognate reversible 2 4 1 1
405 methylation of bleomycin cognate reversible 2 4 1 1
406 methylation of zorbamycin cognate reversible 2 4 1 1
407 paromamine deoxygenase cognate reversible 2 4 1 1
408 clorobiocin pyrrole-2-carboxy methyltransferase cognate reversible 2 4 1 1
409 chondrochloren A methyltransferase cognate reversible 2 4 1 1
410 phosphonoacetaldehyde methylase cognate reversible 2 4 1 1
411 7,8-dihydro-6-hydroxymethylpterin dimethyltransferase cognate reversible 4 5 1 1
412 hopan-22-ol 2-methyltransferase cognate reversible 2 4 1 1
413 tetrahymanol 2-methyltransferase cognate reversible 2 4 1 1
414 hop-21-ene 2-methyltransferase cognate reversible 2 4 1 1
415 hop-17(21)-ene 2-methyltransferase cognate reversible 2 4 1 1
416 bacteriohopanetetrol 2-methyltransferase cognate reversible 2 4 1 1
418 thioacetal methlytransferase cognate reversible 2 4 1 1
419 Ca2+-transporting ATPase cognate reversible 3 4
420 Cu2+-transporting ATPase cognate reversible 3 4
421 H+/K+-exchanging ATPase cognate 3.6.3.10 reversible 4 4
422 Na+/K+-exchanging ATPase cognate 3.6.3.9 reversible 4 5
423 Na+-transporting ATPase cognate 3.6.3.7 reversible 3 4
424 H+-transporting ATPase cognate 3.6.3.6 reversible 3 4
426 ATP phosphohydrolase cognate reversible 2 3
429 Peroxidase generic forward 2 3
430 EP-UMP cyclase cognate 5.-.-.- reversible 2 3 1 2