Reaction: 2-iminoacetate synthase List of reactions

Reaction name: 2-iminoacetate synthase Reaction type: cognate
EC number: Kegg ID:R10246 Rhea ID:26364
Directionality: reversible Curation status: valid Classification: public
Description:Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable S-adenosyl-L-methionine molecule. The first stage of catalysis is reduction of the S-adenosyl-L-methionine to produce methionine and a 5-deoxyadenosin-5-yl radical that is crucial for the conversion of the substrate. Part of the pathway for thiamine biosynthesis.
Curator notes:
ID Type Compound ID Name Stoichiometry Curator notes
chebi 59789 S-adenosyl-L-methionine zwitterion 1
chebi 58315 L-tyrosine zwitterion 1
chebi 57783 NADPH(4-) 1
ID Type Compound ID Name Stoichiometry Curator notes
chebi 77846 dehydroglycine zwitterion 1
chebi 17847 p-cresol 1
chebi 17319 5'-deoxyadenosine 1
chebi 57844 L-methionine zwitterion 1
chebi 58349 NADP(3-) 1

Reaction

2-iminoacetate synthase

+ + + + + +
S-adenosyl-L-methionine zwitterion
59789
L-tyrosine zwitterion
58315
NADPH(4-)
57783
dehydroglycine zwitterion
77846
p-cresol
17847
5'-deoxyadenosine
17319
L-methionine zwitterion
57844
NADP(3-)
58349

EC: | IntEnz: | Kegg: | BioCyc: | BRENDA: |