efd_id common_name superfamily_id superfamily superfamily_evidence_code subgroup_id subgroup family_id family family_evidence_code taxon_ids species type_of_life patric_cid phylogenetic_reference_proteome uniprot_reference_proteome reaction_scheme_id reaction_scheme_name gi genbank_accession_number refseq_accession_number uniprot swissprot swissprot_name trembl microbes_online the_seed length_domain length_full pdb_ids pdb_homologues ec number conserves all functional residues 430921 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming FSM 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) CFM,ISS 53953, 70601 Pyrococcus horikoshii, Pyrococcus horikoshii OT3 Archaea UP000000752 300508514, 300508513, 299689143, 299689142 O58832 DPH2_PYRHO 2-(3-amino-3-carboxypropyl)histidine synthase 370 378 3LZC, 3LZD no 430935 YY S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming FSM 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) CFM,ISS 53953, 70601 Pyrococcus horikoshii, Pyrococcus horikoshii OT3 Archaea UP000000752 499187648, 74571202, 3257521 WP_010885188.1 O58832 DPH2_PYRHO 2-(3-amino-3-carboxypropyl)histidine synthase fig|70601.1.peg.1076 336 342 3LZC, 3LZD no 441648 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 243232, 2190 Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii Archaea UP000000805 UP000000805 15668660, 499172397, 1591186, 2496001 AAB98474.1 NP_247459.1, WP_010869984.1 Q57907 DPH2_METJA 2-(3-amino-3-carboxypropyl)histidine synthase 9056 fig|243232.1.peg.496 338 340 no 441649 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 670386 Polysphondylium pallidum PN500 Invertebrates 281208578 EFA82754.1 598 602 yes 441650 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 10029 Cricetulus griseus Rodents UP000030759 350538521, 537235177, 414744509, 115490615, 123778051 ERE85116.1, AFX06794.1, ABI97860.1 NP_001233722.1 Q002B5 DPH2_CRIGR 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 489 489 yes 441651 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 9913 Bos taurus Mammals UP000009136 UP000009136 147905412, 146231682, 296488943 ABQ12916.1 NP_001071567.2 Q08DM2 DPH2_BOVIN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 489 489 yes 441652 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 229533, 5518 Gibberella zeae PH-1, Gibberella zeae Fungi UP000009057, UP000022177 758210182, 596547695, 558863670, 699032389, 84028907 EYB27522.1, ESU13753.1 XP_011327260.1 Q4I5M4 DPH2_GIBZE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 8847468 fig|229533.1.peg.7484 534 535 yes 441653 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 284593, 5478 Candida glabrata CBS 138, Candida glabrata Fungi UP000002428, UP000054886 50290945, 74609337, 49527216 XP_447905.1 Q6FPD9, A0A0W0CCE8 DPH2_CANGA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} A0A0W0CCE8_CANGB 6616168 541 551 yes 441654 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 284592 Debaryomyces hansenii CBS767 Fungi UP000000599 294658283, 218512014, 202953015 XP_460615.2 Q6BMF6 DPH2_DEBHA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 6609929 586 588 yes 441655 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 8355 Xenopus laevis Vertebrates 147899151, 50417478, 82182563 AAH77348.1 NP_001086718.1 Q6DE00 DPH2_XENLA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 478 478 yes 441656 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 284590, 28985 Kluyveromyces lactis NRRL Y-1140, Kluyveromyces lactis Fungi UP000000598 50306451, 74606593, 49642333 XP_453199.1 Q6CS90 DPH2_KLULA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 6594637 586 587 yes 441657 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 1175444, 1041930 Methanocella conradii, Methanocella sp. HZ254 Archaea UP000005233 504219265, 379321583 AFD00536.1 WP_014406367.1 H8I9T5 H8I9T5_METCZ 316 316 no 441658 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 283643, 214684 Cryptococcus neoformans var. neoformans B-3501A, Cryptococcus neoformans var. neoformans JEC21 Fungi UP000002149 UP000001435, UP000002149 134118553, 58261718, 57230442, 50254656, 338818008, 338818007 AAW46752.1, EAL17403.1 XP_772050.1, XP_568269.1 P0CN21, P0CN20 DPH2_CRYNB, DPH2_CRYNJ 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 6590709 515 515 yes 441659 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 284591 Yarrowia lipolytica CLIB122 Fungi UP000001300 UP000001300 50545455, 74635887, 49646130 XP_500265.1 Q6CGE7 DPH2_YARLI 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 6598681 480 481 yes 441660 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 9544, 9541 Macaca mulatta, Macaca fascicularis Primates UP000006718 UP000006718, UP000009130 380789837, 355745225, 355557923 AFE66794.1, EHH49850.1, EHH14703.1 489 489 yes 441661 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 293091, 768065, 362976 Haloquadratum walsbyi, Haloquadratum walsbyi C23, Haloquadratum walsbyi DSM 16790 Archaea UP000007954, UP000001975 504369157, 385803961, 403212920, 339729453 WP_014556259.1, YP_005840361.1 G0LJE2, Q18H43 G0LJE2_HALWC, Q18H43_HALWD 344 344 no 441662 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 284811, 1034331 Ashbya gossypii ATCC 10895, Ashbya gossypii FDAG1 Fungi UP000000591 UP000000591, UP000032842 45190703, 374108180, 44983682, 74693564 AEY97087.1, AAS52781.1 NP_984957.1 Q757B6 DPH2_ASHGO 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 6622326 fig|33169.1.peg.2602 565 582 yes 441663 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 9031 Gallus gallus Vertebrates UP000000539 UP000000539 57529649, 82082149, 53130864 NP_001006538.1 Q5ZKI2 DPH2_CHICK 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 476 477 yes 441664 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 51589, 634497, 1417673 Haloarcula hispanica, Haloarcula hispanica ATCC 33960, Haloarcula hispanica N601 Archaea UP000005629, UP000018572 503806107, 344211507, 564121811, 343782862 AHB65633.1, AEM56839.1 WP_014040101.1, YP_004795827.1 V5TKM8, G0HY38 V5TKM8_HALHI, G0HY38_HALHT 347 348 no 441665 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 45351 Nematostella vectensis Invertebrates UP000001593 UP000001593 156368701, 156214791, 187471043 EDO35768.1 XP_001627831.1 A7SKJ3 DPH2_NEMVE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 527 531 yes 441666 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 10090 Mus musculus Rodents UP000000589 UP000000589 33468993, 148698587, 81880405, 12858449, 12847167 EDL30534.1 NP_080620.1 Q9CR25 DPH2_MOUSE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} fig|10090.3.peg.10210 489 489 yes 441667 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 352472, 44689 Dictyostelium discoideum AX4, Dictyostelium discoideum Invertebrates UP000002195 UP000002195 166240480, 165988619, 187471042 EDR41076.1 XP_001732995.1 B0G132 DPH2_DICDI 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 588 588 yes 441668 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 6239 Caenorhabditis elegans Invertebrates UP000001940 UP000001940 392891564, 6226755, 3874105 NP_001254257.1 Q09454 DPH2_CAEEL 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} fig|6239.3.peg.7296 476 476 yes 441669 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 9601 Pongo abelii Primates UP000001595 197097804, 75042465, 55726307 NP_001124904.1 Q5RE82 DPH2_PONAB 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 489 489 yes 441670 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 9913 Bos taurus Mammals UP000009136 UP000009136 115305070, 122132304 AAI23672.1 Q08DM2 DPH2_BOVIN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 489 489 yes 441671 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 9606 Homo sapiens Primates UP000005640 UP000005640 194388564 Q9BQC3 DPH2_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 335 354 no 441672 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 284812, 4896 Schizosaccharomyces pombe 972h-, Schizosaccharomyces pombe Fungi UP000002485 UP000002485 19113176, 3451294, 1723275 NP_596384.1 Q10206 DPH2_SCHPO 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 9061002, 6579926 fig|4896.1.peg.2250 495 503 yes 441673 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 559292, 889517, 4932 Saccharomyces cerevisiae S288c, Saccharomyces cerevisiae CEN.PK113-7D, Saccharomyces cerevisiae Fungi UP000002311 UP000002311, UP000013192 6322657, 392298234, 23332111, 765109, 285813078, 486339, 416911, 395234, 296987 EIW09332.1, AAN27052.1, AAA64990.1 NP_012730.1 P32461 DPH2_YEAST 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 6584073 fig|4932.3.peg.3707, fig|559292.3.peg.3220 528 534 yes 441674 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 9606, 32630 Homo sapiens, synthetic construct Primates, Synthetic UP000005640 UP000005640 21536476, 568531525, 414744515, 119627475, 60655701, 60655699, 30583701, 16877418, 13112015, 12655077, 189054906, 74761201 AHD74017.1, AFX06797.1, EAX07070.1, AAX32414.1, AAX32413.1, AAP36099.1, AAH16956.1, AAH03181.1, AAH01389.1 NP_001375.2 Q9BQC3 DPH2_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} fig|9606.3.peg.1024 489 489 yes 441675 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 1294373, 1294364, 1294347, 1294312, 307796 Saccharomyces cerevisiae YJM1443, Saccharomyces cerevisiae YJM1401, Saccharomyces cerevisiae YJM1326, Saccharomyces cerevisiae YJM456, Saccharomyces cerevisiae YJM789 Fungi UP000032928, UP000033167, UP000033180, UP000032948, UP000007060 767178224, 767175501, 767168544, 767032382, 151941728 AJS52443.1, AJS49731.1, AJS44686.1, AJS33898.1, EDN60089.1 528 534 yes 441676 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 7955 Danio rerio Vertebrates UP000000437 UP000000437 148229745, 141795881, 160010406 AAI34940.1 NP_001082866.1 A4QN59 DPH2_DANRE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 491 498 yes 441677 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 261658 Dictyostelium fasciculatum Invertebrates 470265772, 328875388 EGG23753.1 XP_004361604.1 585 606 yes 441678 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 586 588 yes 441679 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 9606 Homo sapiens Primates UP000005640 UP000005640 88853059, 568531524 AHD74016.1 NP_001034678.1 Q9BQC3 DPH2_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 261 261 no 441680 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 237561, 1094985 Candida albicans SC5314, Candida albicans P37005 Fungi UP000000559 UP000030576, UP000030160 68487004, 68486697, 723213250, 703963710, 46434189, 46434030, 74584779 KHC86851.1, KGQ90016.1, EAK93606.1, EAK93452.1 XP_712627.1, XP_712777.1 Q59SJ9 DPH21_CANAL Diphthamide biosynthesis protein 2-1 529 529 yes 441681 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 227321 Aspergillus nidulans FGSC A4 Fungi UP000000560 UP000000560 67538018, 40743170, 259484635, 74595337 EAA62360.1 XP_662783.1 Q5B2Q1 DPH2_EMENI 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 581 582 yes 441682 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 237561 Candida albicans SC5314 Fungi UP000000559 UP000030576 68485552, 68485457, 46434890, 46434842 EAK94289.1, EAK94242.1 XP_713359.1, XP_713406.1 Q59SJ9 DPH21_CANAL Diphthamide biosynthesis protein 2-1 211 212 no 441683 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 330879, 1437362 Aspergillus fumigatus Af293, Aspergillus fumigatus Z5 Fungi UP000002530, UP000053005 70991509, 846917291, 66848236, 74670996 KMK63038.1, EAL88565.1 XP_750603.1 Q4WN99 DPH2_ASPFU 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 563 565 yes 441684 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 10116 Rattus norvegicus Rodents UP000002494 UP000002494 62543509, 149035519, 62203109, 81882362 EDL90200.1, AAH92656.1 NP_001015007.1 Q568Y2 DPH2_RAT 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} fig|10116.3.peg.23763 489 489 yes 441685 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 367110 Neurospora crassa OR74A Fungi UP000001805 UP000001805 85095130, 28921488, 74615831 EAA30794.1 XP_960030.1 Q7S5C0 DPH2_NEUCR 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 8962728 fig|5141.1.peg.3956 598 602 yes 441686 uncharacterized Radical SAM superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming ISS 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) ISS 237561 Candida albicans SC5314 Fungi UP000000559 UP000030576 68492443, 46431105 EAK90746.1 XP_710022.1 Q59SJ9 DPH21_CANAL Diphthamide biosynthesis protein 2-1 145 145 no 441696 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 362976 Haloquadratum walsbyi DSM 16790 Archaea UP000001975 Q18H43 Q18H43_HALWD 345 346 no 441697 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2224, 349307 Methanosaeta thermophila, Methanosaeta thermophila PT Archaea UP000000674 500016062, 116754924, 116666375 ABK15402.1 WP_011696780.1, YP_844042.1 A0B9M8 A0B9M8_METTP 1935342 fig|349307.9.peg.1599 325 334 no 441698 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 331117 Neosartorya fischeri NRRL 181 Fungi UP000006702 119468040, 119405978 EAW15929.1 XP_001257826.1 563 565 no 441699 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7091 Bombyx mori Invertebrates UP000005204 114052366, 87248483 ABD36294.1 NP_001040240.1 402 416 no 441700 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 341663 Aspergillus terreus NIH2624 Fungi UP000007963 115384002, 114196240 EAU37940.1 XP_001208548.1 426 428 no 441701 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 306901 Chaetomium globosum CBS 148.51 Fungi UP000001056 116204565, 88176294 EAQ83762.1 XP_001228093.1 297 300 no 441702 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7159 Aedes aegypti Invertebrates UP000008820 157109955, 108878871 EAT43096.1 XP_001650896.1 512 514 no 441703 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3702 Arabidopsis thaliana Plants UP000006548 UP000006548 10176920 456 468 no 441704 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9606 Homo sapiens Primates UP000005640 UP000005640 116686106, 119610975, 119610973, 269849559 EAW90569.1, EAW90567.1 NP_001374.3 Q9BZG8 DPH1_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} fig|9606.3.peg.12842 435 443 no 441705 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 341663 Aspergillus terreus NIH2624 Fungi UP000007963 115390789, 114193823 EAU35523.1 XP_001212899.1 452 452 no 441706 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2277, 384616 Pyrobaculum islandicum, Pyrobaculum islandicum DSM 4184 Archaea UP000002595 500086135, 119871907, 119673315 ABL87571.1 WP_011762148.1, YP_929914.1 A1RRI9 A1RRI9_PYRIL 2044607 fig|384616.5.peg.387 303 303 no 441707 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 344612 Aspergillus clavatus NRRL 1 Fungi UP000006701 121715836, 119403684 EAW14101.1 XP_001275527.1 425 431 no 441708 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2303, 273075 Thermoplasma acidophilum, Thermoplasma acidophilum DSM 1728 Archaea UP000001024 10639398 Q9HLH3 Q9HLH3_THEAC fig|273075.1.peg.257 333 349 no 441709 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10090, 32630 Mus musculus, synthetic construct Rodents, Synthetic UP000000589 UP000000589 118026919, 157169770, 148680850, 81862238 AAI52730.1, EDL12797.1 NP_652762.2 Q5NCQ5 DPH1_MOUSE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} fig|10090.3.peg.24711 424 438 no 441710 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 272557, 56636 Aeropyrum pernix K1, Aeropyrum pernix Archaea UP000002518 118431053, 499163958, 116062379 NP_147240.2, WP_010865753.1 Q9YEY7 Q9YEY7_AERPE 3100 fig|272557.1.peg.348 345 354 no 441711 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54248, 415426 Hyperthermus butylicus, Hyperthermus butylicus DSM 5456 Archaea UP000002593 500146781, 123979185 ABM81466.1 WP_011822784.1 A2BNA5 A2BNA5_HYPBU fig|415426.7.peg.1805 333 345 no 441712 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9913 Bos taurus Mammals UP000009136 UP000009136 116004025, 74267744, 122140125 AAI03409.1 NP_001070367.1 Q3SYT1 DPH1_BOVIN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 428 438 no 441713 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 321614 Phaeosphaeria nodorum SN15 Fungi UP000001055 UP000001055 169606774, 111065147 EAT86267.1 XP_001796807.1 572 573 no 441714 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 70448 Ostreococcus tauri Plants UP000009170 308806081 XP_003080352.1 1040 1040 no 441715 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3702 Arabidopsis thaliana Plants UP000006548 UP000006548 15240408, 332010170, 21436215, 20259528, 110742463 AED97553.1, AAM51395.1, AAM13884.1 NP_201009.1 10110811 fig|3702.11.peg.5918 446 453 no 441716 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 344612 Aspergillus clavatus NRRL 1 Fungi UP000006701 121710018, 119400775 EAW11199.1 XP_001272625.1 569 570 no 441717 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 64091, 2242, 478009 Halobacterium sp. NRC-1, Halobacterium salinarum, Halobacterium salinarum R1 Archaea UP000000554 UP000000554, UP000001321 15789998, 499205058, 169235721, 10580422, 167726787 AAG19302.1 NP_279822.1, WP_010902598.1, YP_001688921.1 Q9HR56, B0R4A8 Q9HR56_HALSA, B0R4A8_HALS3 3796468, 68791 fig|64091.1.peg.838 343 344 no 441718 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6689 Litopenaeus vannamei Invertebrates 51895764, 122079954 AAU13908.1 Q3T7C9 DPH1_LITVA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 420 423 no 441719 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9606 Homo sapiens Primates UP000005640 UP000005640 530361989, 119627476, 77369009, 193787124 EAX07071.1, ABA66757.1 XP_005270616.1 413 413 no 441720 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 331117 Neosartorya fischeri NRRL 181 Fungi UP000006702 119481341, 119408853 EAW18802.1 XP_001260699.1 441 445 no 441721 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1175445, 351160 Methanocella arvoryzae, uncultured methanogenic archaeon RC-I Archaea UP000000663 500969996, 110622681 WP_012034635.1 Q0W0Y4 Q0W0Y4_METAR fig|351160.3.peg.317 315 315 no 441722 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 306901 Chaetomium globosum CBS 148.51 Fungi UP000001056 116203783, 88175903 EAQ83371.1 XP_001227702.1 464 464 no 441723 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 70448 Ostreococcus tauri Plants UP000009170 308811825 XP_003083220.1 524 1197 no 441724 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9597, 9598 Pan paniscus, Pan troglodytes Primates UP000002277 UP000065018, UP000002277 397491965, 114665638, 410294784 JAA25992.1 XP_003816906.1, XP_511255.2 fig|9598.2.peg.14230 435 443 no 441725 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7159 Aedes aegypti Invertebrates UP000008820 157130751, 108871787 EAT36012.1 XP_001661994.1 369 372 no 441726 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2269, 368408 Thermofilum pendens, Thermofilum pendens Hrk 5 Archaea UP000000641 500076535, 119719791, 119524911 ABL78283.1 WP_011752548.1, YP_920286.1 A1RYK3 A1RYK3_THEPD 2007902 fig|368408.5.peg.946 328 340 no 441727 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7091 Bombyx mori Invertebrates UP000005204 114051592, 95102620 ABF51248.1 NP_001040357.1 456 458 no 441728 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 115449593, 215765293, 215704455, 113538035, 47848173, 47847884 NP_001048504.1 472 474 no 441729 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 46770, 414004 Cenarchaeum symbiosum, Cenarchaeum symbiosum A Archaea UP000000758 503248586, 118195704 ABK78622.1 WP_013483247.1 A0RZ55 A0RZ55_CENSY 318 331 no 441730 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2234, 1344584, 224325 Archaeoglobus fulgidus, Archaeoglobus fulgidus DSM 8774, Archaeoglobus fulgidus DSM 4304 Archaea UP000054307, UP000028501, UP000002199 499181758, 668356732, 2648743 AIG98803.1, AAB89446.1 WP_010879298.1 A0A075WML9, O28472 A0A075WML9_ARCFL, O28472_ARCFU fig|224325.1.peg.1791, fig|257309.1.peg.291 302 310 no 441731 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 70771, 444157 Thermoproteus neutrophilus, Thermoproteus neutrophilus V24Sta Archaea UP000001694 501319436, 171186179, 170935391 ACB40652.1 WP_012351071.1, YP_001795098.1 B1YAK3 B1YAK3_PYRNV 7322560 fig|444157.3.peg.1761 303 303 no 441732 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 145262, 187420 Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus str. Delta H Archaea UP000005223 499179392, 2622425 AAB85797.1 WP_010876932.1 O27374 O27374_METTH fig|187420.1.peg.1291, fig|196600.1.peg.4890 328 330 no 441733 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 436907 Vanderwaltozyma polyspora DSM 70294 Fungi UP000000267 156843021, 156115226 EDO16722.1 XP_001644580.1 417 421 no 441734 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7227, 32630 Drosophila melanogaster, synthetic construct Invertebrates, Synthetic UP000000803 UP000000803 442631748, 24662841, 21356957, 440215645, 220953130, 220943026, 23093637, 17862158, 7294688 AGB94416.1, ACL89108.1, ACL84056.1, AAN11880.1, AAL39556.1, AAF50025.1 NP_001261722.1, NP_729735.1, NP_648496.1 fig|7227.3.peg.9410 442 454 no 441735 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 420 426 no 441736 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 178306, 13773 Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum Archaea UP000002439 UP000002439 18313748, 499318573, 18161304 AAL64597.1 NP_560415.1, WP_011009065.1 Q8ZU11 Q8ZU11_PYRAE 184098 fig|178306.1.peg.2105 303 303 no 441737 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10116 Rattus norvegicus Rodents UP000002494 UP000002494 157786646, 187469465, 149053385 AAI66808.1, EDM05202.1 NP_001099279.1 424 438 no 441738 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 379508 Lodderomyces elongisporus NRRL YB-4239 Fungi UP000001996 149248132, 146448407 EDK42795.1 XP_001528453.1 437 441 no 441739 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 55529 Guillardia theta Plants 162606106, 13794488 AAK39863.1 XP_001713568.1 fig|55529.1.peg.388 382 414 no 441740 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3055 Chlamydomonas reinhardtii Plants UP000006906 UP000006906 159477343, 158275099 EDP00878.1 XP_001696770.1 371 371 no 441741 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2173, 420247 Methanobrevibacter smithii, Methanobrevibacter smithii ATCC 35061 Archaea UP000001992 500589405, 148552435 ABQ87563.1 WP_011954460.1 A5UMY5 A5UMY5_METS3 fig|420247.6.peg.1331 332 334 no 441742 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7220 Drosophila erecta Invertebrates UP000008711 194869284, 190654206 EDV51449.1 XP_001972423.1 444 454 no 441743 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39152, 426368 Methanococcus maripaludis, Methanococcus maripaludis C7 Archaea UP000002298 500697101, 150034140 ABR66253.1 WP_011977563.1 A6VIH7 A6VIH7_METM7 fig|426368.9.peg.1198 304 309 no 441744 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 332648 Botryotinia fuckeliana B05.10 Fungi 154321960 XP_001560295.1 573 612 no 441745 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 665079 Sclerotinia sclerotiorum 1980 UF-70 Fungi UP000001312 UP000001312 156043305, 154695043 EDN94781.1 XP_001588209.1 A7EZ89 A7EZ89_SCLS1 434 445 no 441746 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 50339, 273116 Thermoplasma volcanium, Thermoplasma volcanium GSS1 Archaea UP000001017 499220057 WP_010917597.1 Q978Q2 Q978Q2_THEVO fig|273116.1.peg.1339 332 336 no 441747 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 412030, 5888 Paramecium tetraurelia strain d4-2, Paramecium tetraurelia Invertebrates UP000000600 145528876, 124417832 XP_001450232.1 399 401 no 441748 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7222 Drosophila grimshawi Invertebrates UP000001070 195037609, 193894449 EDV93315.1 XP_001990253.1 482 482 no 441749 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 29829 Lipomyces starkeyi Fungi 133925939 ABO43721.1 177 177 no 441750 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 125584137 EAZ25068.1 419 423 no 441751 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 126793, 5855 Plasmodium vivax SaI-1, Plasmodium vivax Invertebrates UP000008333 156102244, 148805689 EDL47088.1 XP_001616815.1 476 479 no 441752 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7240 Drosophila simulans Invertebrates UP000000304 195589583, 194196540 EDX10116.1 XP_002084531.1 439 454 no 441753 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 322104 Scheffersomyces stipitis CBS 6054 Fungi UP000002258 150864963, 149386219 ABN65964.2 XP_001383993.2 6626635 559 560 no 441754 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 464988 Hemiselmis andersenii Plants 160331105, 159765707 ABW97935.1 XP_001712260.1 402 417 no 441755 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 515849 Podospora anserina S mat+ Fungi UP000001197 171689250, 681097246, 170944587 XP_001909565.1 B2B0X3 B2B0X3_PODAN 439 449 no 441756 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 46245 Drosophila pseudoobscura pseudoobscura Invertebrates UP000001819 125979729, 54640881 EAL29632.1 XP_001353897.1 452 464 no 441757 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 42879, 419665 Methanococcus aeolicus, Methanococcus aeolicus Nankai-3 Archaea UP000001106 500684334, 150014035 ABR56486.1 WP_011973618.1 A6UVG4 A6UVG4_META3 fig|419665.8.peg.943 329 331 no 441758 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 426418 Pyrenophora tritici-repentis Pt-1C-BFP Fungi UP000001471 189199450, 187983161 EDU48649.1 XP_001936062.1 468 475 no 441759 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5061 Aspergillus niger Fungi UP000068243 134076507 538 538 no 441760 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7222 Drosophila grimshawi Invertebrates UP000001070 195016037, 193897809 EDV96675.1 XP_001984327.1 450 461 no 441761 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 43687, 399549 Metallosphaera sedula, Metallosphaera sedula DSM 5348 Archaea UP000056255, UP000000242 500928754, 676316356, 145702862 AIM27988.1, ABP96004.1 WP_012021791.1 A0A088E7M0, A4YHV2 A0A088E7M0_9CREN, A4YHV2_METS5 fig|399549.6.peg.1827 328 332 no 441762 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 125576808, 77549704, 62733967 EAZ18030.1, ABA92501.1, AAX96076.1 504 506 no 441763 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9606 Homo sapiens Primates UP000005640 UP000005640 194388588 432 453 no 441764 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7217 Drosophila ananassae Invertebrates UP000007801 194748274, 190623855 EDV39379.1 XP_001956573.1 444 456 no 441765 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7260 Drosophila willistoni Invertebrates UP000007798 195451316, 194168946 EDW83847.1 XP_002072861.1 475 476 no 441766 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1294383, 1294367, 1294366, 1294350, 1294306, 1294303, 285006 Saccharomyces cerevisiae YJM1527, Saccharomyces cerevisiae YJM1417, Saccharomyces cerevisiae YJM1415, Saccharomyces cerevisiae YJM1338, Saccharomyces cerevisiae YJM244, Saccharomyces cerevisiae YJM189, Saccharomyces cerevisiae RM11-1a Fungi UP000032944, UP000033177, UP000033186, UP000033164, UP000032972, UP000032975, UP000008335 767181912, 767176402, 767176100, 767171274, 767009755, 767008384, 190409652 AJS55419.1, AJS50629.1, AJS50328.1, AJS45591.1, AJS30955.1, AJS30055.1, EDV12917.1 528 534 no 441767 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 273063, 111955 Sulfolobus tokodaii str. 7, Sulfolobus tokodaii Archaea UP000001015 15922594, 499289057, 15623384 NP_378263.1, WP_010980347.1 Q96YA5 Q96YA5_SULTO 138733, 373661 fig|273063.1.peg.2431 330 332 no 441768 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 46245 Drosophila pseudoobscura pseudoobscura Invertebrates UP000001819 125773949, 54637969 EAL27371.1 XP_001358233.1 481 481 no 441769 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 379508 Lodderomyces elongisporus NRRL YB-4239 Fungi UP000001996 149236862, 146451843 EDK46099.1 XP_001524308.1 516 520 no 441770 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 436017 Ostreococcus lucimarinus CCE9901 Plants UP000001568 145353856, 144581453 ABO99509.1 XP_001421216.1 447 452 no 441771 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5661, 435258 Leishmania donovani, Leishmania infantum JPCM5 Invertebrates 398018887, 146093187, 322500838, 134071068 XP_003862608.1, XP_001466705.1 371 373 no 441772 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 484906, 5865 Babesia bovis T2Bo, Babesia bovis Invertebrates UP000002173 156087114, 154798217 EDO07396.1 XP_001610964.1 441 442 no 441773 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2287, 555311, 273057 Sulfolobus solfataricus, Sulfolobus solfataricus 98/2, Sulfolobus solfataricus P2 Archaea UP000001974 UP000033085, UP000001493, UP000001974 497676399, 800906817, 800904124, 800901425, 261601903, 13813437 AKA78998.1, AKA76306.1, AKA73608.1, ACX91506.1, AAK40633.1 WP_009990583.1 A0A0E3K5R9, D0KRY7, Q980J8 A0A0E3K5R9_SULSF, D0KRY7_SULS9, Q980J8_SULSO fig|273057.1.peg.266 329 333 no 441774 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 412030, 5888 Paramecium tetraurelia strain d4-2, Paramecium tetraurelia Invertebrates UP000000600 145534105, 124420496 XP_001452797.1 394 396 no 441775 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 339724 Ajellomyces capsulatus NAm1 Fungi UP000009297 154281791, 150411887 EDN07275.1 XP_001541708.1 422 425 no 441776 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 425265 Malassezia globosa CBS 7966 Fungi UP000008837 164662100, 159106074 EDP44958.1 XP_001732172.1 351 359 no 441777 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6279 Brugia malayi Invertebrates UP000026912 170576485, 671418070 XP_001893649.1 162 163 no 441778 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 76887, 397948 Caldivirga maquilingensis, Caldivirga maquilingensis IC-167 Archaea UP000001137 501137663, 157920533 ABW01960.1 WP_012186179.1 A8MDV4 A8MDV4_CALMQ fig|397948.3.peg.1106 259 337 no 441779 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 358766, 456442 Candidatus Methanoregula boonei, Candidatus Methanoregula boonei 6A8 Archaea UP000002408 501056274, 154000259 ABS56682.1 WP_012107740.1 A7IAC1 A7IAC1_METB6 fig|456442.10.peg.2158 311 317 no 441780 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 294746 Meyerozyma guilliermondii ATCC 6260 Fungi UP000001997 190348998 EDK41561.2 384 400 no 441781 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1294386, 1294379, 1294370, 1294367, 1294366, 1294359, 1294357, 1294356, 1294354, 1294353, 1294351, 1294350, 1294349, 1294348, 1294346, 1294344, 1294342, 1294341, 1294339, 1294338, 1294336, 1294335, 1293430, 1294332, 1294330, 1294329, 1294328, 1294327, 1294326, 1294325, 1294324, 1294323, 1294322, 1294320, 1294319, 1294318, 1294317, 1294311, 1294310, 947044, 468558, 1294309, 1294308, 1294307, 1294306, 1294304, 1294303, 1296266, 1294331, 1177187, 1182968, 1182966, 764100, 764102, 574961, 545124, 285006, 643680 Saccharomyces cerevisiae YJM1574, Saccharomyces cerevisiae YJM1477, Saccharomyces cerevisiae YJM1433, Saccharomyces cerevisiae YJM1417, Saccharomyces cerevisiae YJM1415, Saccharomyces cerevisiae YJM1387, Saccharomyces cerevisiae YJM1385, Saccharomyces cerevisiae YJM1383, Saccharomyces cerevisiae YJM1356, Saccharomyces cerevisiae YJM1355, Saccharomyces cerevisiae YJM1341, Saccharomyces cerevisiae YJM1338, Saccharomyces cerevisiae YJM1336, Saccharomyces cerevisiae YJM1332, Saccharomyces cerevisiae YJM1311, Saccharomyces cerevisiae YJM1304, Saccharomyces cerevisiae YJM1252, Saccharomyces cerevisiae YJM1250, Saccharomyces cerevisiae YJM1244, Saccharomyces cerevisiae YJM1242, Saccharomyces cerevisiae YJM1202, Saccharomyces cerevisiae YJM1199, Saccharomyces cerevisiae YJM1129, Saccharomyces cerevisiae YJM996, Saccharomyces cerevisiae YJM990, Saccharomyces cerevisiae YJM987, Saccharomyces cerevisiae YJM984, Saccharomyces cerevisiae YJM981, Saccharomyces cerevisiae YJM978, Saccharomyces cerevisiae YJM975, Saccharomyces cerevisiae YJM972, Saccharomyces cerevisiae YJM969, Saccharomyces cerevisiae YJM693, Saccharomyces cerevisiae YJM683, Saccharomyces cerevisiae YJM682, Saccharomyces cerevisiae YJM681, Saccharomyces cerevisiae YJM627, Saccharomyces cerevisiae YJM453, Saccharomyces cerevisiae YJM450, Saccharomyces cerevisiae YJM428, Saccharomyces cerevisiae YJM326, Saccharomyces cerevisiae YJM271, Saccharomyces cerevisiae YJM270, Saccharomyces cerevisiae YJM248, Saccharomyces cerevisiae YJM244, Saccharomyces cerevisiae YJM193, Saccharomyces cerevisiae YJM189, Saccharomyces cerevisiae YJM1078, Saccharomyces cerevisiae YJM993, Saccharomyces cerevisiae P283, Saccharomyces cerevisiae P301, Saccharomyces cerevisiae R008, Saccharomyces cerevisiae VL3, Saccharomyces cerevisiae FostersB, Saccharomyces cerevisiae JAY291, Saccharomyces cerevisiae AWRI1631, Saccharomyces cerevisiae RM11-1a, Saccharomyces cerevisiae EC1118 Fungi UP000032920, UP000032922, UP000033174, UP000033177, UP000033186, UP000033171, UP000033175, UP000033196, UP000033169, UP000033160, UP000033189, UP000033164, UP000033183, UP000033190, UP000033178, UP000032924, UP000032954, UP000032935, UP000032942, UP000032963, UP000032976, UP000032986, UP000032970, UP000032978, UP000032923, UP000032985, UP000032929, UP000032984, UP000032977, UP000032950, UP000032933, UP000032973, UP000032955, UP000032959, UP000032949, UP000032937, UP000032939, UP000032936, UP000032960, UP000032981, UP000032979, UP000032980, UP000032951, UP000032983, UP000032972, UP000032956, UP000032975, UP000032926, UP000025223, UP000019320, UP000025164, UP000025243, UP000007238, UP000000309, UP000008073, UP000008988, UP000008335, UP000000286 766282037, 766175817, 766032755, 765955659, 765939280, 765910976, 765874868, 765851940, 765827025, 765826831, 765826233, 765816274, 765802018, 765783617, 765717199, 765706822, 765706431, 765706048, 765705661, 765705467, 765705086, 765704892, 765704308, 765703925, 765703730, 765703535, 765703344, 765703149, 765702955, 765702760, 765702355, 765689006, 765688582, 765685211, 765685016, 765684815, 765684621, 765669357, 765665245, 765647271, 765615685, 765576335, 765570989, 765568618, 765546319, 765542906, 765531010, 761460060, 628175523, 584476125, 584370526, 584365300, 323354567, 323304536, 256273734, 207344375, 190406314, 259147153 AJR53452.1, AJR52185.1, AJR50478.1, AJR49909.1, AJR49716.1, AJR48433.1, AJR48049.1, AJR47883.1, AJR47499.1, AJR47306.1, AJR46926.1, AJR46733.1, AJR46540.1, AJR46347.1, AJR45967.1, AJR45594.1, AJR45205.1, AJR44824.1, AJR44439.1, AJR44246.1, AJR43867.1, AJR43674.1, AJR43093.1, AJR42712.1, AJR42518.1, AJR42324.1, AJR42134.1, AJR41940.1, AJR41747.1, AJR41553.1, AJR41360.1, AJR41166.1, AJR40994.1, AJR40621.1, AJR40427.1, AJR40239.1, AJR40046.1, AJR38924.1, AJR38539.1, AJR38347.1, AJR38154.1, AJR37781.1, AJR37586.1, AJR37391.1, AJR37199.1, AJR36860.1, AJR36665.1, AJP39372.1, AHY75904.1, EWH17876.1, EWG90471.1, EWG85302.1, EGA86403.1, EGA58301.1, EEU08660.1, EDZ71541.1, EDV09581.1 423 425 no 441782 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3218 Physcomitrella patens Plants UP000006727 UP000006727 168023214, 162684573 EDQ70974.1 XP_001764133.1 441 463 no 441783 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7234 Drosophila persimilis Invertebrates UP000008744 195174167, 194115528 EDW37571.1 XP_002027852.1 453 465 no 441784 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 294746 Meyerozyma guilliermondii ATCC 6260 Fungi UP000001997 190345395 EDK37271.2 556 557 no 441785 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3218 Physcomitrella patens Plants UP000006727 UP000006727 168012697, 162689737 EDQ76107.1 XP_001759038.1 397 417 no 441786 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 451804 Aspergillus fumigatus A1163 Fungi UP000001699 159124159 EDP49277.1 563 565 no 441787 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 45351 Nematostella vectensis Invertebrates UP000001593 UP000001593 156367349, 156214288, 187471041 EDO35280.1 XP_001627380.1 A7SLX5 DPH1_NEMVE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 460 465 no 441788 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7230 Drosophila mojavensis Invertebrates UP000009192 195108831, 193915590 EDW14457.1 XP_001998996.1 475 475 no 441789 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7234 Drosophila persimilis Invertebrates UP000008744 195143881, 194101868 EDW23911.1 XP_002012925.1 177 177 no 441790 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7234 Drosophila persimilis Invertebrates UP000008744 195143883, 194101869 EDW23912.1 XP_002012926.1 231 238 no 441791 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 330879, 1476192, 451804 Aspergillus fumigatus Af293, Aspergillus fumigatus var. RP-2014, Aspergillus fumigatus A1163 Fungi UP000002530, UP000028372, UP000001699 71001790, 666427732, 159129636, 66853214, 74675355 KEY75391.1, EDP54750.1, EAL93538.1 XP_755576.1 Q4X0S7 DPH1_ASPFU 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 441 445 no 441792 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 370354 Entamoeba dispar SAW760 Invertebrates UP000008076 167382234, 165901713 EDR27754.1 XP_001736021.1 337 344 no 441793 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 420245 Leishmania braziliensis MHOM/BR/75/M2904 Invertebrates 154344186, 134065371 XP_001568037.1 764 764 no 441794 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2187, 406327 Methanococcus vannielii, Methanococcus vannielii SB Archaea UP000001107 501013124, 150012636 ABR55088.1 WP_012066003.1 A6URG6 A6URG6_METVS fig|406327.7.peg.1221 303 309 no 441795 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6239 Caenorhabditis elegans Invertebrates UP000001940 UP000001940 17552166, 8247965, 3874296 NP_497750.1 P49958 DPH1_CAEEL 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} fig|6239.3.peg.9197 395 396 no 441796 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 339724 Ajellomyces capsulatus NAm1 Fungi UP000009297 154273320, 150416024 EDN11368.1 XP_001537512.1 596 596 no 441797 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 36329, 5843, 1237627, 478859, 57266, 5835, 57270, 1036726, 1036725, 1036724, 1036723 Plasmodium falciparum 3D7, Plasmodium falciparum NF54, Plasmodium falciparum UGT5.1, Plasmodium falciparum Santa Lucia, Plasmodium falciparum 7G8, Plasmodium falciparum CAMP/Malaysia, Plasmodium falciparum Palo Alto/Uganda, Plasmodium falciparum NF135/5.C10, Plasmodium falciparum Tanzania (2000708), Plasmodium falciparum FCH/4, Plasmodium falciparum Vietnam Oak-Knoll (FVO) Invertebrates UP000001450 UP000001450, UP000030673, UP000030697, UP000030666, UP000030688, UP000030694, UP000019103, UP000019114, UP000030708, UP000030656, UP000030690 124808425, 583223072, 583212392, 579327691, 579115988, 574998410, 574992658, 574978503, 574971909, 574968262, 574747847, 23497201 EWC86094.1, EWC74134.1, EUT78631.1, EUR64696.1, ETW58919.1, ETW53774.1, ETW40292.1, ETW34162.1, ETW31319.1, ETW16222.1, AAN36748.1 XP_001348309.1 fig|36329.1.peg.2011 482 487 no 441798 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3702 Arabidopsis thaliana Plants UP000006548 UP000006548 15231723, 332646426, 53749154, 19715609, 6996299 AEE79947.1, AAU90062.1, AAL91627.1 NP_191522.1 10098362 491 491 no 441799 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7245 Drosophila yakuba Invertebrates UP000002282 195501488, 194183918 EDW97529.1 XP_002097817.1 469 469 no 441800 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 338192, 436308 Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1 Archaea UP000000792 501172127, 161529071, 160340372 ABX13459.1 WP_012215946.1, YP_001582897.1 A9A5Y1 A9A5Y1_NITMS 3726387 fig|436308.3.peg.1559 323 331 no 441801 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 284812, 4896 Schizosaccharomyces pombe 972h-, Schizosaccharomyces pombe Fungi UP000002485 UP000002485 19113201, 74582212, 2995340 NP_596409.1 O59713 DPH1_SCHPO 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 6579954, 9061645 fig|4896.1.peg.2275 433 436 no 441802 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 160233, 453591 Ignicoccus hospitalis, Ignicoccus hospitalis KIN4/I Archaea UP000000262 501072119, 156937788, 156566772 ABU82177.1 WP_012123141.1, YP_001435584.1 A8AB75 A8AB75_IGNH4 3778980 fig|453591.8.peg.1005 305 310 no 441803 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3055 Chlamydomonas reinhardtii Plants UP000006906 UP000006906 159472254, 158276929 EDP02699.1 XP_001694266.1 271 272 no 441804 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 436907 Vanderwaltozyma polyspora DSM 70294 Fungi UP000000267 156842354, 156115190 EDO16687.1 XP_001644545.1 571 579 no 441805 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 332648 Botryotinia fuckeliana B05.10 Fungi 154316524 XP_001557583.1 296 303 no 441806 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7244 Drosophila virilis Invertebrates UP000008792 195379690, 194155768 EDW70952.1 XP_002048610.1 438 455 no 441807 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8355 Xenopus laevis Vertebrates 160014077 Q6GPQ5 DPH1_XENLA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 432 439 no 441808 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9606 Homo sapiens Primates UP000005640 UP000005640 189054206 356 363 no 441809 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6279 Brugia malayi Invertebrates UP000026912 170581288 XP_001895619.1 310 311 no 441810 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 665079 Sclerotinia sclerotiorum 1980 UF-70 Fungi UP000001312 UP000001312 156060983, 154700038 EDN99776.1 XP_001596414.1 A7EBE8 A7EBE8_SCLS1 565 565 no 441811 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 515849 Podospora anserina S mat+ Fungi UP000001197 171679078, 681100002, 170937610 XP_001904487.1 B2AFP8 B2AFP8_PODAN 1125 1127 no 441812 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121277, 340102 Pyrobaculum arsenaticum, Pyrobaculum arsenaticum DSM 13514 Archaea UP000001567 500231234, 145591573, 145283341 ABP50923.1 WP_011900830.1, YP_001153575.1 A4WKK6 A4WKK6_PYRAR 3495509 fig|340102.3.peg.1306 143 303 no 441813 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10228 Trichoplax adhaerens Invertebrates UP000009022 UP000009022 195997109, 190589199 EDV29221.1 XP_002108423.1 476 478 no 441814 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 294746 Meyerozyma guilliermondii ATCC 6260 Fungi UP000001997 146419472 XP_001485698.1 556 557 no 441815 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 455580 uncultured marine crenarchaeote HF4000_ANIW141N1 Archaea 167043348 ABZ08052.1 B3T643 B3T643_9ARCH 324 331 no 441816 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 294746 Meyerozyma guilliermondii ATCC 6260 Fungi UP000001997 146413336 XP_001482639.1 380 400 no 441817 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9796 Equus caballus Mammals UP000002281 UP000002281 149693722 XP_001497750.1 489 489 no 441818 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7240 Drosophila simulans Invertebrates UP000000304 195570808, 194199323 EDX12899.1 XP_002103396.1 469 469 no 441819 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7220 Drosophila erecta Invertebrates UP000008711 194900872, 190651682 EDV48937.1 XP_001979979.1 468 468 no 441820 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 420245 Leishmania braziliensis MHOM/BR/75/M2904 Invertebrates 154342140, 134064347 XP_001567018.1 371 373 no 441821 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7176 Culex quinquefasciatus Invertebrates UP000002320 170055462, 167875416 EDS38799.1 XP_001863593.1 470 470 no 441822 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 283643, 214684 Cryptococcus neoformans var. neoformans B-3501A, Cryptococcus neoformans var. neoformans JEC21 Fungi UP000002149 UP000001435, UP000002149 134107435, 58259287, 57223193, 50260296, 338818006, 338818005 AAW41237.1, EAL22955.1 XP_777602.1, XP_567056.1 P0CN19, P0CN18 DPH1_CRYNB, DPH1_CRYNJ 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 6589380 520 529 no 441823 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 426418 Pyrenophora tritici-repentis Pt-1C-BFP Fungi UP000001471 189190958, 187973424 EDU40923.1 XP_001931818.1 575 577 no 441824 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6279 Brugia malayi Invertebrates UP000026912 170575664 XP_001893331.1 444 445 no 441825 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 322104 Scheffersomyces stipitis CBS 6054 Fungi UP000002258 126135694, 126091569 ABN66342.1 XP_001384371.1 6626714 414 421 no 441826 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39152, 402880 Methanococcus maripaludis, Methanococcus maripaludis C5 Archaea UP000000253 500196028, 132664139 ABO35785.1 WP_011869235.1 A4G001 A4G001_METM5 fig|402880.8.peg.1468 304 309 no 441827 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39152, 444158 Methanococcus maripaludis, Methanococcus maripaludis C6 Archaea UP000000791 501148455, 159886644 ABX01581.1 WP_012193473.1 A9A8A8 A9A8A8_METM6 fig|444158.3.peg.754 304 309 no 441828 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7176 Culex quinquefasciatus Invertebrates UP000002320 170043701, 167867040 EDS30423.1 XP_001849514.1 456 456 no 441829 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 431895 Monosiga brevicollis MX1 Invertebrates 167522104, 163776348 EDQ89968.1 XP_001745390.1 425 428 no 441830 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39946 Oryza sativa Indica Group Plants UP000007015 125534010 EAY80558.1 405 407 no 441831 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 425265 Malassezia globosa CBS 7966 Fungi UP000008837 164660644, 159105345 EDP44231.1 XP_001731445.1 586 588 no 441832 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2261, 186497 Pyrococcus furiosus, Pyrococcus furiosus DSM 3638 Archaea UP000001013 499321708, 18893130 AAL81187.1 WP_011012200.1 Q8U1Z1 Q8U1Z1_PYRFU fig|186497.1.peg.1100 336 344 no 441833 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 284813 Encephalitozoon cuniculi GB-M1 Fungi UP000000819 19074383, 19069025 NP_585889.1 6623891 fig|6035.1.peg.792 277 319 no 441834 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 486041 Laccaria bicolor S238N-H82 Fungi UP000001194 170111312, 164638218 EDR02497.1 XP_001886860.1 496 496 no 441835 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 126793, 5855 Plasmodium vivax SaI-1, Plasmodium vivax Invertebrates UP000008333 156101972, 148805553 EDL46952.1 XP_001616679.1 689 690 no 441836 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 184922 Giardia lamblia ATCC 50803 Invertebrates UP000001548 UP000001548 159113789, 157435223 EDO79446.1 XP_001707120.1 364 393 no 441837 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 29292, 272844 Pyrococcus abyssi, Pyrococcus abyssi GE5 Archaea UP000009139 499169969, 5458551 WP_010868245.1 Q9UZL8 Q9UZL8_PYRAB fig|272844.1.peg.1182 333 339 no 441838 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7217 Drosophila ananassae Invertebrates UP000007801 194743288, 190627169 EDV42693.1 XP_001954132.1 471 472 no 441839 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 273116 Thermoplasma volcanium GSS1 Archaea UP000001017 14325602 Q978Q2 Q978Q2_THEVO fig|273116.1.peg.1339 338 345 no 441840 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 321614 Phaeosphaeria nodorum SN15 Fungi UP000001055 UP000001055 169609176, 160701797 EAT85141.2 XP_001798007.1 396 736 no 441841 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9606 Homo sapiens Primates UP000005640 UP000005640 193786856 192 199 no 441842 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5851 Plasmodium knowlesi strain H Invertebrates UP000031513 221060166, 193810802 XP_002260728.1 704 706 no 441843 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 332952, 510516, 1197718, 1160506 Aspergillus flavus NRRL3357, Aspergillus oryzae RIB40, Aspergillus oryzae 100-8, Aspergillus oryzae 3.042 Fungi UP000001875, UP000006564, UP000026920, UP000002812 238496629, 169774771, 635507553, 391868781, 220694430, 83769716 KDE79563.1, EIT77990.1, EED50774.1 XP_002379550.1, XP_001821853.1 431 436 no 441844 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 436017 Ostreococcus lucimarinus CCE9901 Plants UP000001568 145348549, 144578939 ABO97002.1 XP_001418709.1 516 517 no 441845 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 242507 Magnaporthe oryzae 70-15 Fungi UP000009058 389634877, 351647424 EHA55284.1 XP_003715091.1 601 601 no 441846 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 484906, 5865 Babesia bovis T2Bo, Babesia bovis Invertebrates UP000002173 156088641, 154798981 EDO08159.1 XP_001611727.1 439 447 no 441847 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 455554 uncultured marine microorganism HF4000_APKG8D23 Environmental samples 167044929 ABZ09595.1 367 369 no 441848 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7238 Drosophila sechellia Invertebrates UP000001292 195328889, 194120087 EDW42130.1 XP_002031144.1 469 469 no 441849 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2280, 399550 Staphylothermus marinus, Staphylothermus marinus F1 Archaea UP000000254 500164312, 126465536, 126014359 ABN69737.1 WP_011838928.1, YP_001040645.1 A3DM77 A3DM77_STAMF 2090987 fig|399550.6.peg.644 347 347 no 441850 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1294384, 1294383, 1294376, 1294374, 1294373, 1294371, 1294369, 1294368, 1294364, 1294358, 1294352, 1294347, 1294345, 1294343, 1294388, 1294337, 1294334, 1294333, 1294321, 1294316, 1294315, 1294314, 1294313, 1294312, 502869, 947042, 1294305, 764101, 307796 Saccharomyces cerevisiae YJM1549, Saccharomyces cerevisiae YJM1527, Saccharomyces cerevisiae YJM1450, Saccharomyces cerevisiae YJM1444, Saccharomyces cerevisiae YJM1443, Saccharomyces cerevisiae YJM1434, Saccharomyces cerevisiae YJM1419, Saccharomyces cerevisiae YJM1418, Saccharomyces cerevisiae YJM1401, Saccharomyces cerevisiae YJM1386, Saccharomyces cerevisiae YJM1342, Saccharomyces cerevisiae YJM1326, Saccharomyces cerevisiae YJM1307, Saccharomyces cerevisiae YJM1273, Saccharomyces cerevisiae YJM1615, Saccharomyces cerevisiae YJM1208, Saccharomyces cerevisiae YJM1190, Saccharomyces cerevisiae YJM1133, Saccharomyces cerevisiae YJM689, Saccharomyces cerevisiae YJM555, Saccharomyces cerevisiae YJM554, Saccharomyces cerevisiae YJM541, Saccharomyces cerevisiae YJM470, Saccharomyces cerevisiae YJM456, Saccharomyces cerevisiae YJM451, Saccharomyces cerevisiae YJM320, Saccharomyces cerevisiae YJM195, Saccharomyces cerevisiae FostersO, Saccharomyces cerevisiae YJM789 Fungi UP000032953, UP000032944, UP000033161, UP000032932, UP000032928, UP000033176, UP000033181, UP000032967, UP000033167, UP000033194, UP000033185, UP000033180, UP000033192, UP000032971, UP000032940, UP000032938, UP000032968, UP000032931, UP000032974, UP000032957, UP000032958, UP000032934, UP000032921, UP000032948, UP000032961, UP000032952, UP000032947, UP000007237, UP000007060 766281655, 766281458, 766121686, 766121312, 766120565, 766060419, 766003499, 765977384, 765938901, 765893364, 765826641, 765747864, 765707011, 765706624, 765706243, 765705272, 765704698, 765704503, 765688314, 765684428, 765683583, 765680398, 765680208, 765669895, 765669162, 765597423, 765543098, 323308665, 151943064 AJR53072.1, AJR52876.1, AJR51615.1, AJR51243.1, AJR51052.1, AJR50671.1, AJR50285.1, AJR50098.1, AJR49339.1, AJR48240.1, AJR47117.1, AJR46158.1, AJR45782.1, AJR45397.1, AJR45018.1, AJR44052.1, AJR43481.1, AJR43287.1, AJR40811.1, AJR39854.1, AJR39674.1, AJR39495.1, AJR39306.1, AJR39117.1, AJR38730.1, AJR37974.1, AJR37051.1, EGA61906.1, EDN61399.1 423 425 no 441851 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 36329, 5843 Plasmodium falciparum 3D7, Plasmodium falciparum NF54 Invertebrates UP000001450 UP000001450, UP000030673 124808943, 583222599, 23497342 EWC85650.1, AAN36887.1 XP_001348448.1 fig|36329.1.peg.2150 744 744 no 441852 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 425011, 380704, 5061 Aspergillus niger CBS 513.88, Aspergillus niger ATCC 1015, Aspergillus niger Fungi UP000006706, UP000009038, UP000068243 145232302, 350634517, 134056515 EHA22879.1 XP_001399601.1 428 434 no 441853 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 412030, 5888 Paramecium tetraurelia strain d4-2, Paramecium tetraurelia Invertebrates UP000000600 145513026, 124409777 XP_001442424.1 394 396 no 441854 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 83984, 410358 Methanocorpusculum labreanum, Methanocorpusculum labreanum Z Archaea UP000000365 500157925, 124362586 ABN06394.1 WP_011832595.1 A2SPY8 A2SPY8_METLZ fig|410358.8.peg.219 316 316 no 441855 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7238 Drosophila sechellia Invertebrates UP000001292 195326888, 194119099 EDW41142.1 XP_002030156.1 439 454 no 441856 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5851 Plasmodium knowlesi strain H Invertebrates UP000031513 221060428, 193810933 XP_002260859.1 487 490 no 441857 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 284813 Encephalitozoon cuniculi GB-M1 Fungi UP000000819 19074520 NP_586026.1 Q8SUZ5 DPH1_ENCCU 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 6624031 fig|6035.1.peg.929 388 414 no 441858 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 431895 Monosiga brevicollis MX1 Invertebrates 167527368, 163773434 EDQ87073.1 XP_001748016.1 1029 1075 no 441859 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 368407 Methanoculleus marisnigri JR1 Archaea UP000002146 125862583 ABN57772.1 A3CWM2 A3CWM2_METMJ fig|368407.6.peg.1837 313 315 no 441860 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7230 Drosophila mojavensis Invertebrates UP000009192 195128813, 193920464 EDW19331.1 XP_002008855.1 446 458 no 441861 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7244 Drosophila virilis Invertebrates UP000008792 195395270, 194142968 EDW59371.1 XP_002056259.1 477 478 no 441862 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7245 Drosophila yakuba Invertebrates UP000002282 195493548, 194180566 EDW94177.1 XP_002094465.1 443 454 no 441863 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7227, 32630 Drosophila melanogaster, synthetic construct Invertebrates, Synthetic UP000000803 UP000000803 21357831, 220953170, 220942960, 17862104, 7299937 ACL89128.1, ACL84023.1, AAL39529.1, AAF55111.1 NP_650402.1 fig|7227.3.peg.12828 469 469 no 441864 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7260 Drosophila willistoni Invertebrates UP000007798 195440558, 194164193 EDW79094.1 XP_002068108.1 452 464 no 441865 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 181486, 410359 Pyrobaculum calidifontis, Pyrobaculum calidifontis JCM 11548 Archaea UP000001431 500175372, 126459727, 126249448 ABO08539.1 WP_011849797.1, YP_001056005.1 A3MV72 A3MV72_PYRCJ 2105268 fig|410359.7.peg.1165 302 302 no 441866 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10228 Trichoplax adhaerens Invertebrates UP000009022 UP000009022 196011726, 190581502 EDV21578.1 XP_002115726.1 370 371 no 441867 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 486041 Laccaria bicolor S238N-H82 Fungi UP000001194 170088130, 164650488 EDR14729.1 XP_001875288.1 424 425 no 441868 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 347515 Leishmania major strain Friedlin Invertebrates 157875199, 68129075 XP_001686002.1 663 666 no 441869 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 477693, 490899 Desulfurococcus kamchatkensis, Desulfurococcus kamchatkensis 1221n Archaea UP000006903 501638998, 218766339 ACL11738.1 WP_012609079.1 B8D6K7 B8D6K7_DESK1 fig|490899.4.peg.1447 333 341 no 441870 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4577 Zea mays Plants UP000007305 226508206, 219885573, 414873856 ACL53161.1 NP_001146073.1 512 514 no 441871 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 246969 Thermococcus sp. AM4 Archaea UP000009277 503889254, 214033923 EEB74749.1 WP_014123248.1 B7R142 B7R142_9EURY 332 344 no 441872 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 432359 Toxoplasma gondii VEG Invertebrates UP000002226 557736095, 820698554 ESS32100.1 567 571 no 441873 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 561896 Postia placenta Mad-698-R Fungi UP000001743 242222484, 220723734 EED77850.1 XP_002476960.1 412 412 no 441874 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 43080, 425944, 439386, 429572 Sulfolobus islandicus, Sulfolobus islandicus L.D.8.5, Sulfolobus islandicus Y.G.57.14, Sulfolobus islandicus L.S.2.15 Archaea UP000001404, UP000002308, UP000001747 502120232, 284446217, 228010418, 227457255 ADB87719.1, ACP46180.1, ACP35942.1 WP_012713994.1 C3MRC9, D2PDE9, C3N7I6 C3MRC9_SULIL, D2PDE9_SULID, C3N7I6_SULIY 329 333 no 441875 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3988 Ricinus communis Plants UP000008311 255576225, 223531546 EEF33376.1 XP_002529006.1 427 434 no 441876 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 294747 Candida tropicalis MYA-3404 Fungi UP000002037 255724578, 240135109 EER34663.1 XP_002547218.1 421 427 no 441877 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121224 Pediculus humanus corporis Invertebrates UP000009046 242004628, 212506147 EEB10444.1 XP_002423182.1 405 410 no 441878 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578460, 40302 Nosema ceranae BRL01, Nosema ceranae Fungi UP000009082, UP000034350 300705882, 817546833, 239604261 KKO75477.1, EEQ81607.1 XP_002995278.1 A0A0F9YSE6 A0A0F9YSE6_9MICR 340 350 no 441879 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 502779 Paracoccidioides brasiliensis Pb01 Fungi UP000002059 295662791 XP_002791949.1 450 465 no 441880 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7739 Branchiostoma floridae Invertebrates UP000001554 UP000001554 260820572, 229290943 EEN61618.1 XP_002605608.1 437 443 no 441881 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 508771 Toxoplasma gondii ME49 Invertebrates UP000001529 237831923, 527312921 EPT29550.1 XP_002365259.1 556 559 no 441882 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 423536 Perkinsus marinus ATCC 50983 Invertebrates UP000007800 294938457, 239893549 EER13907.1 XP_002782112.1 219 291 no 441883 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 237561, 1095000, 1094994, 1094993, 1094986, 1165368, 1094996, 1094997, 1094991, 1094982, 1094987, 1094984, 1094981, 1094989, 1094990, 1094988, 1094985, 294748 Candida albicans SC5314, Candida albicans P78042, Candida albicans P75010, Candida albicans P37039, Candida albicans P60002, Candida albicans Ca6, Candida albicans P57055, Candida albicans P75063, Candida albicans P34048, Candida albicans L26, Candida albicans 19F, Candida albicans P87, Candida albicans 12C, Candida albicans P78048, Candida albicans P57072, Candida albicans GC75, Candida albicans P37005, Candida albicans WO-1 Fungi UP000000559 UP000030576, UP000030499, UP000030551, UP000030453, UP000030594, UP000030442, UP000030186, UP000030191, UP000030193, UP000030190, UP000030192, UP000030189, UP000030187, UP000030161, UP000030165, UP000030162, UP000030160, UP000001429 723214364, 723207974, 723206725, 723191893, 723184749, 723179793, 723172768, 712887483, 712884960, 712880892, 712866436, 712865323, 712862705, 712683741, 703984589, 703983348, 703971078, 703967292, 238882351 KHC87956.1, KHC81625.1, KHC80382.1, KHC65690.1, KHC58600.1, KHC53669.1, KHC46723.1, KGU35175.1, KGU32678.1, KGU28657.1, KGU15378.1, KGU14268.1, KGU11694.1, KGT70771.1, KGR13574.1, KGR12339.1, KGR00192.1, KGQ96448.1, EEQ45989.1 418 426 no 441884 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 403677 Phytophthora infestans T30-4 Plants UP000006643 UP000006643 301103438, 262101560 EEY59612.1 XP_002900805.1 447 459 no 441885 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 296543 Thalassiosira pseudonana CCMP1335 Plants 224005977, 220972468 EED90800.1 XP_002291949.1 749 751 no 441886 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 544712 Ajellomyces capsulatus H143 Fungi UP000002624 240279098 EER42603.1 596 596 no 441887 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 554155 Arthroderma otae CBS 113480 Fungi UP000002035 296812643, 238841915 EEQ31577.1 XP_002846659.1 434 440 no 441888 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 441960, 1077442 Penicillium marneffei ATCC 18224, Penicillium marneffei PM1 Fungi UP000001294, UP000029285 212537285, 679994355, 210068540 KFX46885.1, EEA22631.1 XP_002148798.1 422 426 no 441889 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 342948, 523850 Thermococcus onnurineus, Thermococcus onnurineus NA1 Archaea UP000002727 501568460, 212010043 ACJ17425.1 WP_012572896.1 B6YW59 B6YW59_THEON fig|523850.3.peg.1947 337 344 no 441890 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1294384, 1294386, 1294379, 1294374, 1294370, 1294359, 1294354, 1294351, 1294349, 1294342, 1294339, 1294338, 1293430, 1294332, 1294330, 1294329, 1294328, 1294327, 1294326, 1294325, 1294324, 1294323, 1294318, 1294316, 1294311, 1294309, 1294307, 1294304, 1294331, 1182967, 1182968, 545124 Saccharomyces cerevisiae YJM1549, Saccharomyces cerevisiae YJM1574, Saccharomyces cerevisiae YJM1477, Saccharomyces cerevisiae YJM1444, Saccharomyces cerevisiae YJM1433, Saccharomyces cerevisiae YJM1387, Saccharomyces cerevisiae YJM1356, Saccharomyces cerevisiae YJM1341, Saccharomyces cerevisiae YJM1336, Saccharomyces cerevisiae YJM1252, Saccharomyces cerevisiae YJM1244, Saccharomyces cerevisiae YJM1242, Saccharomyces cerevisiae YJM1129, Saccharomyces cerevisiae YJM996, Saccharomyces cerevisiae YJM990, Saccharomyces cerevisiae YJM987, Saccharomyces cerevisiae YJM984, Saccharomyces cerevisiae YJM981, Saccharomyces cerevisiae YJM978, Saccharomyces cerevisiae YJM975, Saccharomyces cerevisiae YJM972, Saccharomyces cerevisiae YJM969, Saccharomyces cerevisiae YJM681, Saccharomyces cerevisiae YJM555, Saccharomyces cerevisiae YJM453, Saccharomyces cerevisiae YJM271, Saccharomyces cerevisiae YJM248, Saccharomyces cerevisiae YJM193, Saccharomyces cerevisiae YJM993, Saccharomyces cerevisiae R103, Saccharomyces cerevisiae P301, Saccharomyces cerevisiae AWRI1631 Fungi UP000032953, UP000032920, UP000032922, UP000032932, UP000033174, UP000033171, UP000033169, UP000033189, UP000033183, UP000032954, UP000032942, UP000032963, UP000032970, UP000032978, UP000032923, UP000032985, UP000032929, UP000032984, UP000032977, UP000032950, UP000032933, UP000032973, UP000032937, UP000032957, UP000032936, UP000032980, UP000032983, UP000032956, UP000025223, UP000027126, UP000025164, UP000008988 767184978, 767181515, 767180008, 767178519, 767177315, 767174067, 767172557, 767171576, 767170970, 767166684, 767165808, 767165507, 767156723, 767156116, 767155812, 767155510, 767155208, 767154905, 767154603, 767100206, 767050258, 767049972, 767040406, 767039744, 767027188, 767010673, 767010054, 767009156, 628182204, 584374942, 584370040, 207343680 AJS55682.1, AJS56285.1, AJS54221.1, AJS52737.1, AJS51539.1, AJS48302.1, AJS46797.1, AJS45892.1, AJS45288.1, AJS43183.1, AJS42310.1, AJS42010.1, AJS40198.1, AJS39593.1, AJS39290.1, AJS38989.1, AJS38688.1, AJS38386.1, AJS38085.1, AJS37783.1, AJS37480.1, AJS37195.1, AJS35701.1, AJS35102.1, AJS33596.1, AJS31853.1, AJS31253.1, AJS30358.1, AHY76064.1, EWG94833.1, EWG89991.1, EDZ71072.1 528 534 no 441891 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 441375 Cryptosporidium muris RN66 Invertebrates UP000001460 209880129, 209557110 EEA07155.1 XP_002141504.1 527 529 no 441892 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578460 Nosema ceranae BRL01 Fungi UP000009082 300707900, 239605415 EEQ82471.1 XP_002996142.1 281 346 no 441893 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 190192, 2320 Methanopyrus kandleri AV19, Methanopyrus kandleri Archaea UP000001826 20094953, 499329393, 19888198 AAM02730.1 NP_614800.1, WP_011019885.1 Q8TV76 Q8TV76_METKA 233151 fig|190192.1.peg.1513 336 343 no 441894 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 521002, 483214 Methanobrevibacter smithii DSM 2374, Methanobrevibacter smithii DSM 2375 Archaea 288860576, 222435225 EFC92874.1, EEE42390.1 D2ZNM7, B9AG00 D2ZNM7_METSM, B9AG00_METSM fig|420247.6.peg.1331 335 338 no 441895 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 402676 Schizosaccharomyces japonicus yFS275 Fungi UP000001744 213408871, 212003253 EEB08913.1 XP_002175206.1 500 500 no 441896 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1329 1329 no 441897 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 502780 Paracoccidioides brasiliensis Pb18 Fungi UP000001628 734684592, 226286699 EEH42212.1 XP_010762525.1 436 446 no 441898 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 447093 Ajellomyces capsulatus G186AR Fungi UP000001631 225563260 EEH11539.1 421 425 no 441899 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6945 Ixodes scapularis Invertebrates UP000001555 UP000001555 240977021, 215491200 EEC00841.1 XP_002402574.1 483 488 no 441900 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 441960, 1077442 Penicillium marneffei ATCC 18224, Penicillium marneffei PM1 Fungi UP000001294, UP000029285 212540542, 679999953, 210067725 KFX52086.1, EEA21817.1 XP_002150426.1 557 557 no 441901 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6183 Schistosoma mansoni Invertebrates UP000008854 UP000008854 353232896 533 538 no 441902 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 306902 Clavispora lusitaniae ATCC 42720 Fungi UP000007703 260949611, 238846674 EEQ36138.1 XP_002619102.1 606 627 no 441903 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 294747 Candida tropicalis MYA-3404 Fungi UP000002037 255720783, 240135815 EER35368.1 XP_002545326.1 524 524 no 441904 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 284592 Debaryomyces hansenii CBS767 Fungi UP000000599 294657468, 218512013, 199432714 XP_459775.2 Q6BPU5 DPH1_DEBHA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 6611498 416 420 no 441905 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 679716 Trypanosoma brucei gambiense DAL972 Invertebrates UP000002316 788022705, 261334177 XP_011779435.1 655 657 no 441906 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 146826, 519442 Halorhabdus utahensis, Halorhabdus utahensis DSM 12940 Archaea UP000002071 506270747, 257053860, 256692623 ACV12960.1 WP_015790522.1, YP_003131693.1 C7NR47 C7NR47_HALUD 7511001 348 349 no 441907 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 43080, 930943, 426118, 930945, 427318, 427317 Sulfolobus islandicus, Sulfolobus islandicus HVE10/4, Sulfolobus islandicus M.16.4, Sulfolobus islandicus REY15A, Sulfolobus islandicus M.16.27, Sulfolobus islandicus M.14.25 Archaea UP000006395, UP000001479, UP000002664, UP000002307, UP000001350 502109257, 385773778, 238620300, 323477893, 323475161, 238381370, 228020389, 227459866 ADX83131.1, ADX85767.1, ACR42458.1, ACP55796.1, ACP38552.1 WP_012711782.1, YP_005646345.1, YP_002915126.1 C3MXL8, C3MZG4, F0NRI0, F0NII0, C4KIP4 C3MXL8_SULIM, C3MZG4_SULIA, F0NRI0_SULIH, F0NII0_SULIR, C4KIP4_SULIK 7253922 329 333 no 441908 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 352914, 73239 Plasmodium yoelii yoelii str. 17XNL, Plasmodium yoelii yoelii Invertebrates UP000008553 83032696, 23486119 EAA20717.1 XP_729152.1 374 448 no 441909 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 306902 Clavispora lusitaniae ATCC 42720 Fungi UP000007703 260948656, 238848497 EEQ37961.1 XP_002618625.1 497 500 no 441910 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3694 Populus trichocarpa Plants UP000006729 UP000006729 566175949, 550336108 ERP59202.1 XP_006381405.1 496 496 no 441911 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 336963 Uncinocarpus reesii 1704 Fungi UP000002058 258577163, 237903029 EEP77430.1 XP_002542763.1 947 949 no 441912 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 526221 Verticillium albo-atrum VaMs.102 Fungi UP000008698 302412635, 261356726 EEY19154.1 XP_003004150.1 442 450 no 441913 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 187878, 593117 Thermococcus gammatolerans, Thermococcus gammatolerans EJ3 Archaea UP000001488 506338427, 239910137 ACS33028.1 WP_015858146.1 C5A466 C5A466_THEGJ 330 341 no 441914 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2214, 188937 Methanosarcina acetivorans, Methanosarcina acetivorans C2A Archaea UP000002487 UP000002487 499330271, 19914522 AAM04158.1 WP_011020763.1 Q8TSS7 Q8TSS7_METAC fig|188937.1.peg.704 330 335 no 441915 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 222929 Coccidioides posadasii C735 delta SOWgp Fungi UP000009084 303315033, 240107194 EER25379.1 XP_003067524.1 430 439 no 441916 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 644223, 981350 Pichia pastoris GS115, Komagataella pastoris CBS 7435 Fungi UP000000314, UP000006853 254572734, 328354698, 238033275 XP_002493476.1 417 424 no 441917 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4577 Zea mays Plants UP000007305 226497730, 756808568, 413939462, 402641175, 259374504, 195643774 AJN00566.1, AFW74013.1, AFQ83371.1, ACW65096.1, ACG41355.1 NP_001151030.1 479 482 no 441918 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6183 Schistosoma mansoni Invertebrates UP000008854 UP000008854 353233091 403 413 no 441919 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 554373 Moniliophthora perniciosa FA553 Fungi UP000000741 215456549 EEB92559.1 227 247 no 441920 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 336963 Uncinocarpus reesii 1704 Fungi UP000002058 258565399, 237907145 EEP81546.1 XP_002583444.1 298 303 no 441921 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559297 Ajellomyces dermatitidis ER-3 Fungi UP000002039 239610571 EEQ87558.1 437 445 no 441922 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 564608 Micromonas pusilla CCMP1545 Plants UP000001876 303287322, 226455586 EEH52889.1 XP_003062950.1 447 451 no 441923 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 425595 Candidatus Micrarchaeum acidiphilum ARMAN-2 Archaea 255513293 EET89559.1 C7DHY5 C7DHY5_MICA2 307 312 no 441924 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8364 Xenopus (Silurana) tropicalis Vertebrates UP000008143 UP000008143 213982931, 197245570 AAI68479.1 NP_001135627.1 388 391 no 441925 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559297 Ajellomyces dermatitidis ER-3 Fungi UP000002039 239608535 EEQ85522.1 598 598 no 441926 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 83171, 573064 Methanocaldococcus fervens, Methanocaldococcus fervens AG86 Archaea UP000001495 506271449, 256793818 ACV24487.1 WP_015791224.1 C7P7F5 C7P7F5_METFA 318 323 no 441927 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 573826 Candida dubliniensis CD36 Fungi UP000002605 241954012, 223643068 XP_002419727.1 538 538 no 441928 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 554373 Moniliophthora perniciosa FA553 Fungi UP000000741 215441888 EEB88186.1 68 69 no 441929 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559295 Lachancea thermotolerans CBS 6340 Fungi UP000002036 255714196, 238934760 XP_002553380.1 568 569 no 441930 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6183 Schistosoma mansoni Invertebrates UP000008854 UP000008854 353233092 286 293 no 441931 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 500485 Penicillium chrysogenum Wisconsin 54-1255 Fungi UP000000724 255946351, 211588678 XP_002563943.1 431 435 no 441932 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 573826 Candida dubliniensis CD36 Fungi UP000002605 241951570, 223641846 XP_002418507.1 419 426 no 441933 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 481877 Enterocytozoon bieneusi H348 Fungi UP000001742 269859583, 220067067 EED44535.1 XP_002649516.1 361 364 no 441934 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 573826 Candida dubliniensis CD36 Fungi UP000002605 241954050, 223643087 XP_002419746.1 538 614 no 441935 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 64 64 no 441936 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 482561 Paracoccidioides brasiliensis Pb03 Fungi UP000002740 225684740 EEH23024.1 436 446 no 441937 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 294748 Candida albicans WO-1 Fungi UP000001429 238881750 EEQ45388.1 529 529 no 441938 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7739 Branchiostoma floridae Invertebrates UP000001554 UP000001554 260815625, 229287884 EEN58585.1 XP_002602573.1 471 478 no 441939 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4558 Sorghum bicolor Plants UP000000768 UP000018409 242066966, 241934603 EES07748.1 XP_002454772.1 476 487 no 441940 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 403677 Phytophthora infestans T30-4 Plants UP000006643 UP000006643 301119261, 262105870 EEY63922.1 XP_002907358.1 497 497 no 441941 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 296587 Micromonas sp. RCC299 Plants UP000002009 255089423, 226521906 ACO67891.1 XP_002506633.1 426 428 no 441942 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 423536 Perkinsus marinus ATCC 50983 Invertebrates UP000007800 294938924, 239893780 EER14047.1 XP_002782252.1 434 443 no 441943 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559295 Lachancea thermotolerans CBS 6340 Fungi UP000002036 255718379, 238936854 XP_002555470.1 422 423 no 441944 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 296543 Thalassiosira pseudonana CCMP1335 Plants 224000289, 220975025 EED93354.1 XP_002289817.1 439 441 no 441945 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 403677 Phytophthora infestans T30-4 Plants UP000006643 UP000006643 301088620, 262109476 EEY67528.1 XP_002894754.1 500 501 no 441946 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 507601 Toxoplasma gondii GT1 Invertebrates UP000005641 523576023 EPR62723.1 555 559 no 441947 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 564608 Micromonas pusilla CCMP1545 Plants UP000001876 303277019, 226460460 EEH57754.1 XP_003057803.1 613 613 no 441948 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 475088, 521011 Methanosphaerula palustris, Methanosphaerula palustris E1-9c Archaea UP000002457 501693739, 219546930 ACL17380.1 WP_012618699.1 B8GDM9 B8GDM9_METPE fig|521011.3.peg.2203 311 315 no 441949 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559307, 4956 Zygosaccharomyces rouxii CBS 732, Zygosaccharomyces rouxii Fungi UP000008536 254581126, 238939440 XP_002496548.1 426 427 no 441950 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3988 Ricinus communis Plants UP000008311 255579442, 223529863 EEF31794.1 XP_002530564.1 499 499 no 441951 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 679716 Trypanosoma brucei gambiense DAL972 Invertebrates UP000002316 788000608, 261327156 XP_011772422.1 356 357 no 441952 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 43080, 419942 Sulfolobus islandicus, Sulfolobus islandicus Y.N.15.51 Archaea UP000006818 502133998, 228012347 ACP48108.1 WP_012717302.1 C3NFZ0 C3NFZ0_SULIN 329 333 no 441953 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 502779 Paracoccidioides brasiliensis Pb01 Fungi UP000002059 295662120, 226279740 EEH35306.1 XP_002791614.1 593 593 no 441954 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 447093 Ajellomyces capsulatus G186AR Fungi UP000001631 225555776 EEH04067.1 596 596 no 441955 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 482561 Paracoccidioides brasiliensis Pb03 Fungi UP000002740 225682244 EEH20528.1 595 595 no 441956 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121224 Pediculus humanus corporis Invertebrates UP000009046 242023749, 212517716 EEB19555.1 XP_002432293.1 462 466 no 441957 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 379547, 439481 Aciduliprofundum boonei, Aciduliprofundum boonei T469 Archaea UP000001400 495357244, 197624136 EDY36697.1 WP_008081965.1 B5IA68 B5IA68_ACIB4 328 345 no 441958 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559298 Ajellomyces dermatitidis SLH14081 Fungi UP000002038 261192011, 239589729 EEQ72372.1 XP_002622413.1 598 598 no 441959 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 332952, 1392242, 510516 Aspergillus flavus NRRL3357, Aspergillus flavus AF70, Aspergillus oryzae RIB40 Fungi UP000001875, UP000032444, UP000006564 238489933, 768701867, 220698592, 83770906 KJJ28985.1, EED54932.1 XP_002376204.1 572 573 no 441960 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 29760 Vitis vinifera Plants UP000009183 UP000009183 731439149, 731439147, 225466198 XP_010646702.1, XP_010646701.1, XP_002265458.1 457 461 no 441961 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6945 Ixodes scapularis Invertebrates UP000001555 UP000001555 241999242, 215496023 EEC05664.1 XP_002434264.1 357 500 no 441962 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 660122 Nectria haematococca mpVI 77-13-4 Fungi UP000005206 302890048, 256724827 EEU38196.1 XP_003043909.1 547 547 no 441963 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 441375 Cryptosporidium muris RN66 Invertebrates UP000001460 209878364, 209556229 EEA06274.1 XP_002140623.1 473 496 no 441964 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 644223, 981350 Pichia pastoris GS115, Komagataella pastoris CBS 7435 Fungi UP000000314, UP000006853 254568802, 328351979, 238031308 XP_002491511.1 551 551 no 441965 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 500485 Penicillium chrysogenum Wisconsin 54-1255 Fungi UP000000724 255943227, 211587115 XP_002562382.1 568 569 no 441966 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 379547, 439481 Aciduliprofundum boonei, Aciduliprofundum boonei T469 Archaea UP000001400 495361182, 197622116 EDY34691.1 WP_008085901.1 B5IG77 B5IG77_ACIB4 328 345 no 441967 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559298 Ajellomyces dermatitidis SLH14081 Fungi UP000002038 261195324, 239587938 EEQ70581.1 XP_002624066.1 437 445 no 441968 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 508771 Toxoplasma gondii ME49 Invertebrates UP000001529 237842805 XP_002370700.1 1329 1329 no 441969 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 222929, 443226 Coccidioides posadasii C735 delta SOWgp, Coccidioides posadasii str. Silveira Fungi UP000009084, UP000002497 303310283, 320033947, 240104814 EFW15893.1, EER23009.1 XP_003065154.1 600 600 no 441970 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 423536 Perkinsus marinus ATCC 50983 Invertebrates UP000007800 294936658, 239892849 EER13633.1 XP_002781838.1 226 264 no 441971 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 441959 Talaromyces stipitatus ATCC 10500 Fungi UP000001745 242809718, 218716055 EED15477.1 XP_002485430.1 B8MLE4 B8MLE4_TALSN 415 418 no 441972 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 574961 Saccharomyces cerevisiae JAY291 Fungi UP000008073 256274295 EEU09202.1 528 534 no 441973 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 554155 Arthroderma otae CBS 113480 Fungi UP000002035 296817767, 238839673 EEQ29335.1 XP_002849220.1 583 583 no 441974 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 294748 Candida albicans WO-1 Fungi UP000001429 238881770 EEQ45408.1 529 529 no 441975 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 561896 Postia placenta Mad-698-R Fungi UP000001743 242214273, 220727932 EED81837.1 XP_002472960.1 311 752 no 441976 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 643680 Saccharomyces cerevisiae EC1118 Fungi UP000000286 259147651 528 534 no 441977 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8030 Salmo salar Vertebrates 213512070, 197631919 ACH70683.1 NP_001133094.1 495 499 no 441978 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559307, 4956 Zygosaccharomyces rouxii CBS 732, Zygosaccharomyces rouxii Fungi UP000008536 254579080, 238938416 XP_002495526.1 545 553 no 441979 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 544712 Ajellomyces capsulatus H143 Fungi UP000002624 240275851 EER39364.1 422 425 no 441980 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 604354 Thermococcus sibiricus MM 739 Archaea UP000009079 242264461 ACS89143.1 C6A0J8 C6A0J8_THESM 340 350 no 441981 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 57705, 485914 Halomicrobium mukohataei, Halomicrobium mukohataei DSM 12286 Archaea UP000001746 506243667, 257388534, 257170841 ACV48600.1 WP_015763442.1, YP_003178307.1 C7NYR1 C7NYR1_HALMD 7452029 fig|485914.4.peg.1359 347 348 no 441982 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 352914, 73239 Plasmodium yoelii yoelii str. 17XNL, Plasmodium yoelii yoelii Invertebrates UP000008553 82705758, 23482787 EAA18665.1 XP_727100.1 509 510 no 441983 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 598745 Giardia intestinalis ATCC 50581 Invertebrates UP000002488 253742500 EES99330.1 369 384 no 441984 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 192952 Methanosarcina mazei Go1 Archaea UP000000595 20906405 AAM31573.1 Q8PVT3 Q8PVT3_METMA fig|192952.1.peg.1877 330 340 no 441985 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2247, 416348 Halorubrum lacusprofundi, Halorubrum lacusprofundi ATCC 49239 Archaea UP000000740 506389845, 222479245, 222452147 ACM56412.1 WP_015909564.1, YP_002565482.1 B9LUT5 B9LUT5_HALLT 7234255 346 347 no 441986 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39946 Oryza sativa Indica Group Plants UP000007015 218191806 EEC74233.1 220 220 no 441987 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 296587 Micromonas sp. RCC299 Plants UP000002009 255072919, 226515396 ACO61392.1 XP_002500134.1 358 393 no 441988 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 660122 Nectria haematococca mpVI 77-13-4 Fungi UP000005206 302923648, 256734661 EEU48007.1 XP_003053720.1 454 461 no 441989 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 441959 Talaromyces stipitatus ATCC 10500 Fungi UP000001745 242801519, 218717129 EED16550.1 XP_002483784.1 B8MEC3 B8MEC3_TALSN 584 1405 no 441990 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 556484 Phaeodactylum tricornutum CCAP 1055/1 Plants UP000000759 219119426, 217407947 EEC47882.1 XP_002180474.1 433 434 no 441991 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 502780 Paracoccidioides brasiliensis Pb18 Fungi UP000001628 734674174, 226289617 EEH45101.1 XP_010757377.1 595 595 no 441992 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 526221 Verticillium albo-atrum VaMs.102 Fungi UP000008698 302409364, 261358549 EEY20977.1 XP_003002516.1 173 173 no 441993 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4558 Sorghum bicolor Plants UP000000768 UP000018409 242032299, 449635219, 241917398 AGF11834.1, EER90542.1 XP_002463544.1 512 514 no 441994 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 402676 Schizosaccharomyces japonicus yFS275 Fungi UP000001744 213403105, 212000372 EEB06032.1 XP_002172325.1 434 437 no 441995 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3694 Populus trichocarpa Plants UP000006729 UP000006729 224144867, 222862319 EEE99825.1 XP_002325444.1 426 428 no 441996 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 554373 Moniliophthora perniciosa FA553 Fungi UP000000741 215463396 EEB95338.1 83 83 no 441997 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 579137 Methanocaldococcus vulcanius M7 Archaea UP000002063 261369321 ACX72070.1 C9RER8 C9RER8_METVM 330 333 no 441998 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 943167, 1130820, 943119, 432359 Toxoplasma gondii FOU, Toxoplasma gondii GAB2-2007-GAL-DOM2, Toxoplasma gondii p89, Toxoplasma gondii VEG Invertebrates UP000028838, UP000028837, UP000028828, UP000002226 672280561, 672276237, 672264578, 557732728, 820702367 KFG50964.1, KFG47726.1, KFG38382.1, ESS28914.1 1283 1283 no 441999 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 297611610, 255679981 NP_001067661.2 502 658 no 442000 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 423536 Perkinsus marinus ATCC 50983 Invertebrates UP000007800 294882631, 239873523 EER02492.1 XP_002769774.1 434 443 no 442001 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7719 Ciona intestinalis Invertebrates UP000008144 UP000008144 699242297, 198432248 XP_009858554.1, XP_002120734.1 fig|7719.3.peg.5891 510 510 no 442002 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 104421 Camponotus floridanus Invertebrates UP000000311 307187520 EFN72571.1 442 451 no 442003 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578458 Schizophyllum commune H4-8 Fungi UP000007431 302694287, 300110519 EFJ01920.1 XP_003036822.1 483 485 no 442004 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2180, 523846 Methanothermus fervidus, Methanothermus fervidus DSM 2088 Archaea UP000002315 503179425, 311224952 ADP77808.1 WP_013414086.1 E3GW43 E3GW43_METFV 336 337 no 442005 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 663331 Arthroderma benhamiae CBS 112371 Fungi UP000008866 302500882, 291175992 EFE31794.1 XP_003012434.1 637 648 no 442006 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 764097 Saccharomyces cerevisiae AWRI796 Fungi UP000000306 323333139 EGA74539.1 404 411 no 442007 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6669 Daphnia pulex Invertebrates UP000000305 UP000000305 321455636 EFX66764.1 452 467 no 442008 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 663202 Trichophyton verrucosum HKI 0517 Fungi UP000008383 302655228, 291183126 EFE38762.1 XP_003019407.1 472 486 no 442009 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 662760 Candidatus Parvarchaeum acidiphilum ARMAN-4 Archaea 269986649 EEZ92930.1 D2EFC5 D2EFC5_PARA4 230 230 no 442010 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 876142 Encephalitozoon intestinalis ATCC 50506 Fungi UP000002313 303389724, 303302238 ADM11734.1 XP_003073094.1 280 320 no 442011 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 240176 Coprinopsis cinerea okayama7#130 Fungi UP000001861 299747303, 298407457 EAU84561.2 XP_001836944.2 508 510 no 442012 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6253 Ascaris suum Invertebrates UP000017900 324540251 ADY49581.1 109 110 no 442013 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 347515 Leishmania major strain Friedlin Invertebrates 389594023, 321438758 XP_003722260.1 371 373 no 442014 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 861557 Pyrenophora teres f. teres 0-1 Fungi UP000001067 330925926, 311324201 EFQ90655.1 XP_003301255.1 461 475 no 442015 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 145263, 79929 Methanothermobacter marburgensis, Methanothermobacter marburgensis str. Marburg Archaea UP000000345 503061508, 302588899 ADL59274.1 WP_013296484.1 D9PYH6 D9PYH6_METTM 326 329 no 442016 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 744533, 5762 Naegleria gruberi strain NEG-M, Naegleria gruberi Invertebrates UP000006671 290980916, 284086759 EFC40433.1 XP_002673177.1 560 565 no 442017 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 656061, 39416 Tuber melanosporum Mel28, Tuber melanosporum Fungi UP000006911 296420528, 295636027 XP_002839821.1 576 576 no 442018 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 628 630 no 442019 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 744533, 5762 Naegleria gruberi strain NEG-M, Naegleria gruberi Invertebrates UP000006671 290999875, 284096132 EFC49761.1 XP_002682505.1 450 452 no 442020 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 84156, 572546 Archaeoglobus profundus, Archaeoglobus profundus DSM 5631 Archaea UP000001901 502705452, 284012398 ADB58351.1 WP_012940687.1 D2RE07 D2RE07_ARCPA 317 319 no 442021 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 861557 Pyrenophora teres f. teres 0-1 Fungi UP000001067 330938048, 311317175 EFQ86209.1 XP_003305669.1 569 573 no 442022 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 240176 Coprinopsis cinerea okayama7#130 Fungi UP000001861 299748963, 298408217 EAU81544.2 XP_001840272.2 470 538 no 442023 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 81972 Arabidopsis lyrata subsp. lyrata Plants UP000008694 297820792, 297324117 EFH54538.1 XP_002878279.1 493 493 no 442024 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54261, 589924 Ferroglobus placidus, Ferroglobus placidus DSM 10642 Archaea UP000002613 502731594, 288894702 ADC66239.1 WP_012966578.1 D3S0H6 D3S0H6_FERPA 307 316 no 442025 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 34765 Oikopleura dioica Invertebrates UP000001307 313214568 441 441 no 442026 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 595528 Capsaspora owczarzaki ATCC 30864 Invertebrates UP000008743 470322301, 765550674 KJE91295.1 XP_004349201.1 490 515 no 442027 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578458 Schizophyllum commune H4-8 Fungi UP000007431 302683246, 300104996 EFI96401.1 XP_003031304.1 483 483 no 442028 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6253 Ascaris suum Invertebrates UP000017900 324516975 ADY46693.1 235 235 no 442029 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13686 Solenopsis invicta Invertebrates UP000006539 322798704 EFZ20302.1 463 507 no 442030 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 871575 Pichia angusta DL-1 Fungi UP000008673 562972814 ESW98548.1 409 414 no 442031 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 662760 Candidatus Parvarchaeum acidiphilum ARMAN-4 Archaea 269986418 EEZ92705.1 D2EG13 D2EG13_PARA4 100 106 no 442032 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54254, 633148 Thermosphaera aggregans, Thermosphaera aggregans DSM 11486 Archaea UP000002376 502893934, 296241782, 296094366 ADG90317.1 WP_013128910.1, YP_003649269.1 D5TZL7 D5TZL7_THEAM 318 321 no 442033 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2322, 644295 Methanohalobium evestigatum, Methanohalobium evestigatum Z-7303 Archaea UP000000391 502959807, 298675264, 298288252 ADI74218.1 WP_013194783.1, YP_003727014.1 D7E9E6 D7E9E6_METEZ 331 333 no 442034 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 88036 Selaginella moellendorffii Plants UP000001514 302805827, 300147646 EFJ14309.1 XP_002984664.1 422 422 no 442035 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13769, 547559 Natrialba magadii, Natrialba magadii ATCC 43099 Archaea UP000001879 490326344, 289583234, 445574587, 289532787 ELY29086.1, ADD07138.1 WP_004215815.1, YP_003481700.1 D3SU49 D3SU49_NATMM 10325298 353 353 no 442036 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 88036 Selaginella moellendorffii Plants UP000001514 302794865, 300152964 EFJ19604.1 XP_002979196.1 364 371 no 442037 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 510516 Aspergillus oryzae RIB40 Fungi UP000006564 317137666 XP_001727878.2 561 561 no 442038 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 12968 Blastocystis hominis Plants UP000008312 855308889, 300122049 XP_012896671.1 388 389 no 442039 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 764098 Saccharomyces cerevisiae Lalvin QA23 Fungi UP000007236 323348104 EGA82358.1 380 380 no 442040 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3068 Volvox carteri f. nagariensis Plants UP000001058 302842803, 300261655 EFJ45866.1 XP_002952944.1 278 471 no 442041 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 985052, 985053 Vulcanisaeta moutnovskia, Vulcanisaeta moutnovskia 768-28 Archaea UP000007485 503369010, 323707021 ADY00508.1 WP_013603671.1 F0QTG6 F0QTG6_VULM7 326 343 no 442042 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 535722 Arthroderma gypseum CBS 118893 Fungi UP000002669 315050638, 311340008 EFQ99210.1 XP_003174693.1 435 440 no 442043 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 62320, 543526 Haloterrigena turkmenica, Haloterrigena turkmenica DSM 5511 Archaea UP000001903 502707788, 284165082, 284014737 ADB60688.1 WP_012942979.1, YP_003403361.1 D2RSA7 D2RSA7_HALTV 10311796 349 349 no 442044 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 655844, 568076 Metarhizium anisopliae ARSEF 23, Metarhizium robertsii Fungi UP000002498, UP000030151 629725554, 594722260, 322706066 EXV05147.1, EFY97648.1 XP_007823062.1 530 530 no 442045 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 764099 Saccharomyces cerevisiae Vin13 Fungi UP000000307 323336854 EGA78116.1 289 315 no 442046 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 985895 Leptosphaeria maculans JN3 Fungi UP000002668 396464049, 312213188 XP_003836635.1 485 778 no 442047 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 34765 Oikopleura dioica Invertebrates UP000001307 313231004 441 441 no 442048 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 456320 Methanococcus voltae A3 Archaea UP000007722 297378975 ADI37130.1 D7DQK3 D7DQK3_METV3 321 325 no 442049 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5693 Trypanosoma cruzi Invertebrates UP000008313 407850075 EKG04607.1 358 361 no 442050 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 871575 Pichia angusta DL-1 Fungi UP000008673 562973953 ESW99681.1 545 546 no 442051 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2251, 309800, 1227458, 1230452, 1243180 Haloferax volcanii DS2, Haloferax alexandrinus JCM 10717, Haloferax lucentense DSM 14919, Haloferax sp. BAB2207 Archaea UP000011532 490141174, 292655781, 445742249, 445722815, 445581283, 432195651, 291372202 ELZ93744.1, ELZ74466.1, ELY35644.1, ELK52164.1, ADE04429.1 WP_004041521.1, YP_003535678.1 M0GQF2, L5NMS0, M0IE65, D4GZ60 M0GQF2_HALL2, L5NMS0_9EURY, M0IE65_9EURY, D4GZ60_HALVD 10160090 343 344 no 442052 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6334 Trichinella spiralis Invertebrates UP000054776 339265515, 316957350 EFV47079.1 XP_003366117.1 70 71 no 442053 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 334771, 583356 Ignisphaera aggregans, Ignisphaera aggregans DSM 17230 Archaea UP000001304 503068543, 305663454, 304378023 ADM27862.1 WP_013303512.1, YP_003859742.1 E0SNR6 E0SNR6_IGNAA 328 329 no 442054 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5661 Leishmania donovani Invertebrates 398021831, 322502312 XP_003864078.1 762 767 no 442055 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 461 857 no 442056 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 34765 Oikopleura dioica Invertebrates UP000001307 313239217 153 153 no 442057 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 34765 Oikopleura dioica Invertebrates UP000001307 313215156 262 262 no 442058 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 84599, 591019 Staphylothermus hellenicus, Staphylothermus hellenicus DSM 12710 Archaea UP000002573 502907526, 297526179, 297255095 ADI31304.1 WP_013142502.1, YP_003668203.1 D7DAV7 D7DAV7_STAHD 346 347 no 442059 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 164451, 572478 Vulcanisaeta distributa, Vulcanisaeta distributa DSM 14429 Archaea UP000006681 503102169, 307595963, 307551164 ADN51229.1 WP_013336954.1, YP_003902280.1 E1QV38 E1QV38_VULDI 317 344 no 442060 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 535722 Arthroderma gypseum CBS 118893 Fungi UP000002669 315052222, 311340800 EFR00003.1 XP_003175485.1 605 605 no 442061 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 595528 Capsaspora owczarzaki ATCC 30864 Invertebrates UP000008743 470362253, 765548238 KJE88859.1 XP_004365305.1 596 603 no 442062 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 663331 Arthroderma benhamiae CBS 112371 Fungi UP000008866 302509252, 291180156 EFE35941.1 XP_003016586.1 430 441 no 442063 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3068 Volvox carteri f. nagariensis Plants UP000001058 302845638, 300260287 EFJ44507.1 XP_002954357.1 420 420 no 442064 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 12968 Blastocystis hominis Plants UP000008312 855313828, 300176598 XP_012898311.1 375 385 no 442065 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 367189, 797209 Haladaptatus paucihalophilus, Haladaptatus paucihalophilus DX253 Archaea 495255678, 320550107 EFW91762.1 WP_007980433.1 E7QUV5 E7QUV5_9EURY 344 345 no 442066 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 264402 Capsella grandiflora Plants 295831271, 295831269, 295831267, 295831263 ADG39304.1, ADG39303.1, ADG39302.1, ADG39300.1 164 165 no 442067 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 104421 Camponotus floridanus Invertebrates UP000000311 307167457 EFN61030.1 487 598 no 442068 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 985895 Leptosphaeria maculans JN3 Fungi UP000002668 396492468, 312220386 XP_003843806.1 570 571 no 442069 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 81972 Arabidopsis lyrata subsp. lyrata Plants UP000008694 297793763, 297310601 EFH41025.1 XP_002864766.1 447 453 no 442070 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 610380 Harpegnathos saltator Invertebrates UP000008237 749734017, 307213541 EFN88950.1 XP_011149080.1 445 452 no 442071 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 37546 Glossina morsitans morsitans Invertebrates 289740007 ADD18751.1 459 474 no 442072 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7209 Loa loa Invertebrates UP000007040 312076527 XP_003140901.1 475 478 no 442073 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 645133 Glomerella graminicola M1.001 Fungi UP000008782 827069052, 310796531 EFQ31992.1 XP_008096012.1 510 510 no 442074 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 88036 Selaginella moellendorffii Plants UP000001514 302793973, 300153560 EFJ20198.1 XP_002978751.1 422 422 no 442075 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 764098 Saccharomyces cerevisiae Lalvin QA23 Fungi UP000007236 323347702 EGA81966.1 528 534 no 442076 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 610380 Harpegnathos saltator Invertebrates UP000008237 749735895, 307212535 EFN88258.1 XP_011154130.1 408 410 no 442077 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 31234 Caenorhabditis remanei Invertebrates UP000008281 308501447, 308265209 EFP09162.1 XP_003112908.1 404 405 no 442078 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 764100 Saccharomyces cerevisiae VL3 Fungi UP000007238 323354223 EGA86067.1 489 512 no 442079 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 379547, 439481 Aciduliprofundum boonei, Aciduliprofundum boonei T469 Archaea UP000001400 502762162, 289533948 ADD08295.1 WP_012997146.1 D3TCL0 D3TCL0_ACIB4 324 325 no 442080 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 391623 Thermococcus barophilus MP Archaea UP000007478 315184519 ADT84704.1 F0LJR2 F0LJR2_THEBM 345 358 no 442081 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 644281 Methanocaldococcus sp. FS406-22 Archaea UP000002189 502746340, 288939670 ADC70425.1 WP_012981324.1 D3S6G1 D3S6G1_METSF 319 323 no 442082 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 656061, 39416 Tuber melanosporum Mel28, Tuber melanosporum Fungi UP000006911 296417541, 295634347 XP_002838414.1 437 448 no 442083 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 876142 Encephalitozoon intestinalis ATCC 50506 Fungi UP000002313 303389969, 303302361 ADM11856.1 XP_003073216.1 345 347 no 442084 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54120, 679926 Methanoplanus petrolearius, Methanoplanus petrolearius DSM 11571 Archaea UP000006565 503093468, 307155733 ADN35113.1 WP_013328292.1 E1RFW1 E1RFW1_METP4 327 331 no 442085 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 764101 Saccharomyces cerevisiae FostersO Fungi UP000007237 323308310 EGA61556.1 360 366 no 442086 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 413810, 795797 Halalkalicoccus jeotgali, Halalkalicoccus jeotgali B3 Archaea UP000011645 495692585, 300711332, 445581070, 299125015 ELY35433.1, ADJ15354.1 WP_008417164.1, YP_003737146.1 D8J3P7 D8J3P7_HALJB 343 344 no 442087 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7070 Tribolium castaneum Invertebrates UP000007266 642926571, 91085281, 270009112 EFA05560.1 XP_008194925.1, XP_967520.1 431 431 no 442088 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 929439 Leishmania mexicana MHOM/GT/2001/U1103 Invertebrates UP000007259 401428028, 322494745 XP_003878497.1 664 667 no 442089 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 929439 Leishmania mexicana MHOM/GT/2001/U1103 Invertebrates UP000007259 401415770, 322488604 XP_003872380.1 372 373 no 442090 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 764102 Saccharomyces cerevisiae FostersB Fungi UP000000309 323304223 EGA57998.1 528 551 no 442091 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 29760 Vitis vinifera Plants UP000009183 UP000009183 359478316, 296084273 XP_002273627.2 506 506 no 442092 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13686 Solenopsis invicta Invertebrates UP000006539 322780465 EFZ09953.1 339 340 no 442093 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 547558 Methanohalophilus mahii DSM 5219 Archaea UP000001059 292667387 ADE37236.1 D5E7U8 D5E7U8_METMS 326 327 no 442094 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 469 472 no 442095 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 311458 uncultured crenarchaeote 10-H-08 Archaea UP000008120 315427645 E6NA86 E6NA86_9ARCH 336 359 no 442096 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6238 Caenorhabditis briggsae Invertebrates UP000008549 UP000008549 268574016, 187032034 XP_002641985.1 393 396 no 442097 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 663202 Trichophyton verrucosum HKI 0517 Fungi UP000008383 302664003, 291187643 EFE43020.1 XP_003023638.1 603 603 no 442098 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 655827 Metarhizium acridum CQMa 102 Fungi UP000002499 629693403, 322696521 EFY88312.1 XP_007811993.1 461 463 no 442099 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2880 Ectocarpus siliculosus Plants UP000002630 298711266 864 897 no 442100 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 655863 Grosmannia clavigera kw1407 Fungi UP000007796 320586067 EFW98746.1 506 528 no 442101 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 88036 Selaginella moellendorffii Plants UP000001514 302821308, 300139860 EFJ06593.1 XP_002992317.1 364 371 no 442102 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7070 Tribolium castaneum Invertebrates UP000007266 642916924, 270003030 EEZ99477.1 XP_971551.3 fig|405535.8.peg.5662, fig|334406.4.peg.5544, fig|526975.3.peg.980, fig|405534.9.peg.91 404 408 no 442103 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 367775, 1296102 Cryptococcus bacillisporus WM276, Cryptococcus gattii E566 Fungi UP000007805, UP000054394 321250137, 761748919, 317458169 KIY37338.1, ADV19915.1 XP_003191702.1 513 521 no 442104 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 60847, 469382 Halogeometricum borinquense, Halogeometricum borinquense DSM 11551 Archaea UP000006663 492945794, 313126335, 445575229, 312292700 ELY29708.1, ADQ67160.1 WP_006054394.1, YP_004036605.1 E4NL08 E4NL08_HALBP 329 329 no 442105 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 666510 Acidilobus saccharovorans 345-15 Archaea UP000000346 302329403 ADL19598.1 D9Q2R0 D9Q2R0_ACIS3 341 347 no 442106 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 570267, 304371 Methanocella paludicola, Methanocella paludicola SANAE Archaea UP000001882 502664177, 282164074, 282156388 WP_012900155.1, YP_003356459.1 D1YYF4 D1YYF4_METPS 10155808 318 323 no 442107 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 435258 Leishmania infantum JPCM5 Invertebrates 339899033, 321398631 XP_003392760.1 766 771 no 442108 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 31234 Caenorhabditis remanei Invertebrates UP000008281 308510376, 308242285 EFO86237.1 XP_003117371.1 217 217 no 442109 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 67760, 573063 Methanocaldococcus infernus, Methanocaldococcus infernus ME Archaea UP000002061 502865035, 295434094 ADG13265.1 WP_013100011.1 D5VRR2 D5VRR2_METIM 308 310 no 442110 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 670386 Polysphondylium pallidum PN500 Invertebrates 281210226 EFA84394.1 437 439 no 442111 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 98023 Neslia paniculata Plants 295831273 ADG39305.1 163 165 no 442112 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 115547 uncultured archaeon Archaea 268325240 D1J9P8 D1J9P8_9ARCH 340 366 no 442113 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6253 Ascaris suum Invertebrates UP000017900 541045872, 324514682 ERG84689.1, ADY45949.1 387 390 no 442114 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 367775, 1296108, 1296102, 1296103 Cryptococcus bacillisporus WM276, Cryptococcus gattii NT-10, Cryptococcus gattii E566, Cryptococcus gattii EJB2 Fungi UP000007805, UP000053389, UP000054394, UP000054272 321265353, 765282592, 761744260, 757373141, 317463872 KJE05122.1, KIY32814.1, KIR78749.1, ADV25606.1 XP_003197393.1 514 514 no 442115 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 31234 Caenorhabditis remanei Invertebrates UP000008281 308510084, 308242139 EFO86091.1 XP_003117225.1 168 168 no 442116 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 264402 Capsella grandiflora Plants 295831265 ADG39301.1 164 165 no 442117 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 44056 Aureococcus anophagefferens Plants UP000002729 676380499, 323455373 EGB11241.1 XP_009033528.1 367 369 no 442118 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9646 Ailuropoda melanoleuca Mammals UP000008912 281342353 EFB17937.1 403 415 no 442119 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 454284, 443226 Coccidioides posadasii RMSCC 3488, Coccidioides posadasii str. Silveira Fungi UP000054567, UP000002497 855536037, 320035730 KMM70686.1, EFW17671.1 430 439 no 442120 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6669 Daphnia pulex Invertebrates UP000000305 UP000000305 321463107 EFX74125.1 413 415 no 442121 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2273, 765177 Desulfurococcus mucosus DSM 2162 Archaea UP000001068 503326917, 319752598 ADV64356.1 WP_013561578.1 E8RAE6 E8RAE6_DESM0 332 333 no 442122 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 645133 Glomerella graminicola M1.001 Fungi UP000008782 827068345, 310796183 EFQ31644.1 XP_008095664.1 442 449 no 442123 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9986 Oryctolagus cuniculus Mammals UP000001811 291399065 XP_002715202.1 489 489 no 442124 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 554065 Chlorella variabilis Plants UP000008141 552813687, 307103648 EFN51906.1 XP_005844008.1 616 616 no 442125 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 655863 Grosmannia clavigera kw1407 Fungi UP000007796 320590249 EFX02692.1 1137 1137 no 442126 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 554065 Chlorella variabilis Plants UP000008141 552828961, 307107246 EFN55489.1 XP_005847591.1 423 439 no 442127 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 83816, 634498 Methanobrevibacter ruminantium, Methanobrevibacter ruminantium M1 Archaea UP000008680 502719990, 288542134 ADC46018.1 WP_012954974.1 D3DYU8 D3DYU8_METRM 331 335 no 442128 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 115547 uncultured archaeon Archaea 268325705 D1JB13 D1JB13_9ARCH 340 366 no 442129 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 655827 Metarhizium acridum CQMa 102 Fungi UP000002499 629686805, 322699714 EFY91473.1 XP_007808698.1 528 528 no 442130 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 658858 Giardia lamblia P15 Invertebrates UP000008974 308162499 EFO64888.1 360 384 no 442131 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 994838, 662762 Candidatus Parvarchaeum acidophilus ARMAN-5_'5-way FS', Candidatus Parvarchaeum acidophilus ARMAN-5 Archaea 326422569, 290558917 EGD71964.1, EFD92305.1 F2UU13, D6GWV1 F2UU13_PARA5, D6GWV1_PARA5 99 107 no 442132 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9646 Ailuropoda melanoleuca Mammals UP000008912 281354694 EFB30278.1 488 488 no 442133 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9913 Bos taurus Mammals UP000009136 UP000009136 296476866 428 438 no 442134 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 311458 uncultured crenarchaeote 10-H-08 Archaea UP000008120 557693851, 526884527, 343484621, 315425782, 315425740 YP_008796905.1, WP_020863500.1 E6N526 E6N526_9ARCH 336 359 no 442135 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 353152, 5807 Cryptosporidium parvum Iowa II, Cryptosporidium parvum Invertebrates UP000006726 66475530, 46229026, 323509225, 32398804 EAK89875.1 XP_627581.1 488 497 no 442136 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7209 Loa loa Invertebrates UP000007040 312078670 XP_003141839.1 335 341 no 442137 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6334 Trichinella spiralis Invertebrates UP000054776 339244347, 316973022 EFV56656.1 XP_003378099.1 503 734 no 442138 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6334 Trichinella spiralis Invertebrates UP000054776 339237109, 316977120 EFV60275.1 XP_003380109.1 454 479 no 442139 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6238 Caenorhabditis briggsae Invertebrates UP000008549 UP000008549 268532198, 187036929 XP_002631227.1 479 479 no 442140 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2880 Ectocarpus siliculosus Plants UP000002630 298710519 249 250 no 442141 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2880 Ectocarpus siliculosus Plants UP000002630 298710520 36 54 no 442142 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 662762 Candidatus Parvarchaeum acidophilus ARMAN-5 Archaea 290559484 EFD92815.1 D6GVH7 D6GVH7_PARA5 227 230 no 442143 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 764097 Saccharomyces cerevisiae AWRI796 Fungi UP000000306 323332693 EGA74098.1 489 512 no 442144 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559305, 5551, 1215335, 1215334, 1215339, 1215331, 1215329, 1215330, 1215328, 1215337 Trichophyton rubrum CBS 118892, Trichophyton rubrum, Trichophyton rubrum D6, Trichophyton raubitschekii CBS 202.88, Trichophyton rubrum MR1448, Trichophyton soudanense CBS 452.61, Trichophyton kanei CBS 289.86, Trichophyton fischeri CBS 288.86, Trichophyton fischeri CBS 100081, Trichophyton rubrum MR850 Fungi UP000008864, UP000024976, UP000023645, UP000023756, UP000023623, UP000023661, UP000023758, UP000023688, UP000024696 327299074, 861302408, 633059945, 607989914, 607953746, 607941706, 607929753, 607917653, 607905553, 607878872, 326463124 KMQ46564.1, KDB34619.1, EZG17783.1, EZF85465.1, EZF74840.1, EZF64182.1, EZF53519.1, EZF42870.1, EZF23885.1, EGD88577.1 XP_003234230.1 603 603 no 442145 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559882, 647933 Trichophyton equinum CBS 127.97, Trichophyton tonsurans CBS 112818 Fungi UP000009169, UP000009172 326478852, 326469621 EGE02862.1, EGD93630.1 429 440 no 442146 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 771870 Sordaria macrospora k-hell Fungi UP000001881 336261641, 380094720 XP_003345608.1 442 452 no 442147 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39152, 1053692 Methanococcus maripaludis, Methanococcus maripaludis X1 Archaea UP000008889 503764566, 339903638 AEK19080.1 WP_013998642.1 G0H1S3 G0H1S3_METMI 304 309 no 442148 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 69525, 797303 Natrinema pellirubrum, Natrinema pellirubrum DSM 15624 Archaea UP000010843 493183566, 433591556, 445623562, 433306336 ELY76967.1, AGB32148.1 WP_006180863.1, YP_007281052.1 L0JMS6 L0JMS6_NATP1 349 349 no 442149 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578455 Thielavia terrestris NRRL 8126 Fungi UP000008181 367054878, 347005083 AEO71481.1 XP_003657817.1 435 440 no 442150 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10141 Cavia porcellus Rodents UP000005447 348552224 XP_003461928.1 489 489 no 442151 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1104152 Glarea lozoyensis ATCC 74030 Fungi UP000005446 361126433 EHK98434.1 147 195 no 442152 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1001064 Rhodotorula glutinis ATCC 204091 Fungi UP000006141 342321700 EGU13632.1 564 564 no 442153 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 684364 Batrachochytrium dendrobatidis JAM81 Fungi UP000007241 UP000007241 575474430, 328772273 EGF82311.1 XP_006676509.1 479 488 no 442154 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 452589 Trichoderma atroviride IMI 206040 Fungi UP000005426 358396975 EHK46350.1 439 453 no 442155 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 889962 Candidatus Nanosalinarum sp. J07AB56 Archaea 339757105 EGQ40688.1 G0QBD7 G0QBD7_NANSJ 273 330 no 442156 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 103372 Acromyrmex echinatior Invertebrates UP000007755 332019254 EGI59763.1 450 460 no 442157 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 590646 Candida tenuis ATCC 10573 Fungi UP000000707 575514857, 344232506 EGV64385.1 XP_006686699.1 297 298 no 442158 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 590646 Candida tenuis ATCC 10573 Fungi UP000000707 575514859, 344232507 EGV64386.1 XP_006686700.1 414 416 no 442159 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 990316 Methanosaeta concilii GP6 Archaea UP000007807 328929858 AEB69660.1 F4BVP7 F4BVP7_METCG 313 313 no 442160 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 868131 Methanobacterium sp. SWAN-1 Archaea UP000009231 503592713, 333826628 AEG19290.1 WP_013826789.1 F6D511 F6D511_METPW 330 330 no 442161 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1088740, 1001994 Candidatus Nitrosoarchaeum koreensis, Candidatus Nitrosoarchaeum koreensis MY1 Archaea 494816009, 339520707 EGP94430.1 WP_007551417.1 F9CYN6 F9CYN6_9ARCH 324 331 no 442162 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10029 Cricetulus griseus Rodents UP000030759 344258120 EGW14224.1 454 658 no 442163 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 413071 Trichoderma virens Gv29-8 Fungi UP000007115 358379082 EHK16763.1 G9N9Z5 G9N9Z5_HYPVG 448 458 no 442164 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 931890 Eremothecium cymbalariae DBVPG#7215 Fungi UP000006790 363754944, 356891723 AET40870.1 XP_003647687.1 571 571 no 442165 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 81985 Capsella rubella Plants UP000029121 345293909, 345293905, 345293903, 345293901, 345293897 AEN83446.1, AEN83444.1, AEN83443.1, AEN83442.1, AEN83440.1 165 166 no 442166 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 81985 Capsella rubella Plants UP000029121 345293911, 345293907, 345293899 AEN83447.1, AEN83445.1, AEN83441.1 165 166 no 442167 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9785 Loxodonta africana Mammals UP000007646 344287316 XP_003415399.1 489 489 no 442168 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3880 Medicago truncatula Plants UP000002051 357436535, 355477591 AES58794.1 XP_003588543.1 543 612 no 442169 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 756982 Arthrobotrys oligospora ATCC 24927 Fungi UP000008784 748491815, 345568856 EGX51726.1 XP_011119533.1 546 546 no 442170 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 573729 Myceliophthora thermophila ATCC 42464 Fungi UP000007322 367035358, 347014234 AEO61716.1 XP_003666961.1 435 444 no 442171 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 135651 Caenorhabditis brenneri Invertebrates UP000008068 341897308 EGT53243.1 395 396 no 442172 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 721032 Saccharomyces cerevisiae Kyokai no. 7 Fungi UP000001608 349578854 423 425 no 442173 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10029 Cricetulus griseus Rodents UP000030759 537235176, 344252006 ERE85115.1, EGW08110.1 515 515 no 442174 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 889962 Candidatus Nanosalinarum sp. J07AB56 Archaea 339756989 EGQ40572.1 G0QB12 G0QB12_NANSJ 315 326 no 442175 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5932 Ichthyophthirius multifiliis Invertebrates 471231216, 340506732 EGR32812.1 XP_004036798.1 229 259 no 442176 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1042877 Thermococcus sp. 4557 Archaea UP000000874 503778684, 340809838 AEK72995.1 WP_014012678.1 G0HJ66 G0HJ66_THES4 335 342 no 442177 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 544711 Ajellomyces capsulatus H88 Fungi UP000008142 325089391 EGC42701.1 596 596 no 442178 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 563177, 933801 Acidianus hospitalis, Acidianus hospitalis W1 Archaea UP000008458 503541948, 332694641 AEE94108.1 WP_013776024.1 F4B3S1 F4B3S1_ACIHW 327 331 no 442179 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 601 637 no 442180 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1294388, 1294337, 1294322, 1294321, 1294320, 468558, 721032 Saccharomyces cerevisiae YJM1615, Saccharomyces cerevisiae YJM1208, Saccharomyces cerevisiae YJM693, Saccharomyces cerevisiae YJM689, Saccharomyces cerevisiae YJM683, Saccharomyces cerevisiae YJM326, Saccharomyces cerevisiae Kyokai no. 7 Fungi UP000032940, UP000032938, UP000032955, UP000032974, UP000032959, UP000032979, UP000001608 767182194, 767164668, 767049673, 767046414, 767041015, 767012510, 349579382 AJS56882.1, AJS41708.1, AJS36897.1, AJS36601.1, AJS36302.1, AJS32451.1 528 534 no 442181 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10181 Heterocephalus glaber Rodents UP000006813 351704188 EHB07107.1 434 455 no 442182 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 983644 Cordyceps militaris CM01 Fungi UP000001610 573984945, 346321429 EGX91028.1 XP_006670393.1 457 461 no 442183 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 263906 Methanolinea tarda Archaea 494524408 WP_007313861.1 309 313 no 442184 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 572307 Neospora caninum Nc-Liverpool Invertebrates UP000007494 401412532, 820694690, 325120133 XP_003885713.1 1349 1349 no 442185 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13249 Rhodnius prolixus Invertebrates UP000015103 342905990 AEL79278.1 101 103 no 442186 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 498257 Verticillium dahliae VdLs.17 Fungi UP000001611 697081298, 346972296 EGY15748.1 XP_009654112.1 442 450 no 442187 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4950 Torulaspora delbrueckii Fungi 367011979, 359748149 XP_003680490.1 424 425 no 442188 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 112509 Hordeum vulgare subsp. vulgare Plants UP000011116 326516878 505 507 no 442189 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1008460, 529709 Pyrococcus yayanosii, Pyrococcus sp. CH1 Archaea UP000008386 503671105, 334899856 AEH24124.1 WP_013905181.1 F8AHC7 F8AHC7_PYRYC 339 346 no 442190 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 431241, 1344414 Trichoderma reesei QM6a, Trichoderma reesei RUT C-30 Fungi UP000008984, UP000024376 589107345, 572284152, 340518035 ETS07126.1, EGR48277.1 XP_006965695.1 539 539 no 442191 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1089449, 1089457, 1089448, 1089458, 1089452, 660027, 1229664, 660025 Fusarium oxysporum f. sp. vasinfectum 25433, Fusarium oxysporum f. sp. conglutinans race 2 54008, Fusarium oxysporum f. sp. radicis-lycopersici 26381, Fusarium oxysporum f. sp. raphani 54004, Fusarium oxysporum f. sp. melonis 26406, Fusarium oxysporum Fo47, Fusarium oxysporum f. sp. cubense race 1, Fusarium oxysporum Fo5176 Fungi UP000030701, UP000030676, UP000030657, UP000030663, UP000030703, UP000030766, UP000016928, UP000002489 591500928, 591457254, 591408649, 590068584, 590047183, 587705142, 477508151, 342889621 EXM30321.1, EXL89453.1, EXL43786.1, EXK96108.1, EXK49041.1, EWZ51747.1, ENH61445.1, EGU88658.1 445 453 no 442192 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 747676 Melampsora laricis-populina 98AG31 Fungi UP000001072 599376080, 328859800 EGG08908.1 XP_007407882.1 474 476 no 442193 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 890382 Albugo laibachii Nc14 Plants 325189275 518 518 no 442194 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578457, 936435 Serpula lacrymans var. lacrymans S7.9, Serpula lacrymans var. lacrymans S7.3 Fungi UP000008064, UP000008063 597922196, 336386205, 336373371 EGO27351.1, EGO01709.1 XP_007315442.1 536 540 no 442195 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1071381 Tetrapisispora phaffii CBS 4417 Fungi UP000005666 366999124, 357522594 XP_003684298.1 564 570 no 442196 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 756883 halophilic archaeon DL31 Archaea UP000010096 503816294, 345004027, 344319653 AEN04507.1 WP_014050288.1, YP_004806880.1 G2MFV8 G2MFV8_9ARCH 347 347 no 442197 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54252, 694429 Pyrolobus fumarii, Pyrolobus fumarii 1A Archaea UP000001037 503791729, 343459610 AEM38046.1 WP_014025723.1 G0EET2 G0EET2_PYRF1 328 335 no 442198 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1072681 Nanohaloarchaea archaeon G17 Archaea 358034175 EHK02628.1 H0A9B0 H0A9B0_HALSG 86 106 no 442199 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5786 Dictyostelium purpureum Invertebrates UP000001064 UP000001064 330806445, 325078663 EGC32302.1 XP_003291180.1 518 519 no 442200 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 889948 Candidatus Nanosalina sp. J07AB43 Archaea 339758769 EGQ44022.1 G0QEV9 G0QEV9_NANS0 319 340 no 442201 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2189, 880724 Methanotorris igneus, Methanotorris igneus Kol 5 Archaea UP000009227 503564838, 333751232 AEF96311.1 WP_013798914.1 F6BCV0 F6BCV0_METIK 317 319 no 442202 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 44930, 797304 Natronobacterium gregoryi, Natronobacterium gregoryi SP2 Archaea UP000011613 491746676, 429190077, 445613496, 429134295 ELY67195.1, AFZ71306.1 WP_005579809.1, YP_007175755.1 L0ABR3 L0ABR3_NATGS 349 349 no 442203 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 184117, 999630 Thermoproteus uzoniensis, Thermoproteus uzoniensis 768-20 Archaea UP000008138 503444271, 327310011, 326946490 AEA11596.1 WP_013678932.1, YP_004336908.1 F2L147 F2L147_THEU7 59 308 no 442204 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 751944 Halobacterium sp. DL1 Archaea UP000004595 573485283 AHG03689.1 W0JYI1 W0JYI1_9EURY 345 345 no 442205 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13037 Danaus plexippus Invertebrates UP000007151 357628105 EHJ77548.1 456 458 no 442206 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2898 Cryptomonas paramecium Plants 330039160, 327206729 AEA38906.1 XP_003239804.1 370 445 no 442207 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 67593 Phytophthora sojae Plants 695397065, 348686546 EGZ26361.1 XP_009521649.1 464 475 no 442208 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1095631 Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7 Fungi UP000009009 365760211 EHN01950.1 425 428 no 442209 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1006005, 1006006 Metallosphaera cuprina, Metallosphaera cuprina Ar-4 Archaea UP000007812 503502364, 329566422 AEB94527.1 WP_013737025.1 F4G028 F4G028_METCR 330 332 no 442210 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3880 Medicago truncatula Plants UP000002051 357481175 XP_003610873.1 488 575 no 442211 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4950 Torulaspora delbrueckii Fungi 367017424, 359750874 XP_003683210.1 537 545 no 442212 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 768672 Desulfurococcus fermentans DSM 16532 Archaea UP000006175 390190893 AFL65949.1 I3XPS5 I3XPS5_9CREN 332 336 no 442213 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6239 Caenorhabditis elegans Invertebrates UP000001940 UP000001940 392891566, 332078306 NP_001254258.1 Q09454 DPH2_CAEEL 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 169 169 no 442214 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 79923 Clonorchis sinensis Invertebrates UP000008909 358333307 520 526 no 442215 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10181 Heterocephalus glaber Rodents UP000006813 513021354, 351696343 EHA99261.1 XP_004871953.1 489 489 no 442216 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 510951, 510952 Neurospora tetrasperma FGSC 2508, Neurospora tetrasperma FGSC 2509 Fungi UP000008065, UP000008513 698992404, 350288199, 336467176 EGZ69435.1, EGO55340.1 XP_009853183.1 598 602 no 442217 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 67593 Phytophthora sojae Plants 695383593, 348690667 EGZ30481.1 XP_009517756.1 503 504 no 442218 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 510951, 510952 Neurospora tetrasperma FGSC 2508, Neurospora tetrasperma FGSC 2509 Fungi UP000008065, UP000008513 698989822, 350289645, 336468115 EGZ70870.1, EGO56278.1 XP_009851892.1 447 458 no 442219 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 103372 Acromyrmex echinatior Invertebrates UP000007755 746862318, 746862316, 332020435 EGI60855.1 XP_011062068.1, XP_011062067.1 408 410 no 442220 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 759272 Chaetomium thermophilum var. thermophilum DSM 1495 Fungi UP000008066 576034394, 341038836 EGS23828.1 XP_006691070.1 438 444 no 442221 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 431241 Trichoderma reesei QM6a Fungi UP000008984 589102875, 340520695 EGR50931.1 XP_006963460.1 455 462 no 442222 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1001064 Rhodotorula glutinis ATCC 204091 Fungi UP000006141 342321400 EGU13334.1 591 594 no 442223 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 999809 Sporisorium reilianum SRZ2 Fungi UP000008867 343429888 608 613 no 442224 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 653446 Ajellomyces dermatitidis ATCC 18188 Fungi UP000007802 327348995 EGE77852.1 437 445 no 442225 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2271, 768679 Thermoproteus tenax, Thermoproteus tenax Kra 1 Archaea UP000002654 503893194, 352682487, 350275286 WP_014127188.1, YP_004893011.1 G4RK38 G4RK38_THETK 282 309 no 442226 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 886738 Nitrosopumilaceae archaeon SFB1 Archaea UP000004348 329136870 EGG41163.1 F3KNI8 F3KNI8_9ARCH 309 317 no 442227 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1071381 Tetrapisispora phaffii CBS 4417 Fungi UP000005666 367000361, 357523213 XP_003684916.1 417 422 no 442228 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578457, 936435 Serpula lacrymans var. lacrymans S7.9, Serpula lacrymans var. lacrymans S7.3 Fungi UP000008064, UP000008063 597932182, 336382044, 336369261 EGO23195.1, EGN97603.1 XP_007320435.1 519 519 no 442229 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1089457, 1089458, 660025 Fusarium oxysporum f. sp. conglutinans race 2 54008, Fusarium oxysporum f. sp. raphani 54004, Fusarium oxysporum Fo5176 Fungi UP000030676, UP000030663, UP000002489 591446731, 590072129, 342888210 EXL79194.1, EXK99653.1, EGU87575.1 536 536 no 442230 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1064592 Naumovozyma castellii CBS 4309 Fungi UP000001640 366990639, 342300951 XP_003675087.1 423 427 no 442231 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 342949 Pyrococcus sp. NA2 Archaea UP000008293 503514821, 331034905 AEC52717.1 WP_013749267.1 F4HL36 F4HL36_PYRSN 336 344 no 442232 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 653446 Ajellomyces dermatitidis ATCC 18188 Fungi UP000007802 327353562 EGE82419.1 598 598 no 442233 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 573729 Myceliophthora thermophila ATCC 42464 Fungi UP000007322 367031656, 347012382 AEO59866.1 XP_003665111.1 569 569 no 442234 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1104152 Glarea lozoyensis ATCC 74030 Fungi UP000005446 361128736 EHL00664.1 563 563 no 442235 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559304 Millerozyma farinosa CBS 7064 Fungi UP000005222 448099608, 359380614 XP_004199192.1 580 581 no 442236 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559304 Millerozyma farinosa CBS 7064 Fungi UP000005222 448116136, 359383850 XP_004202982.1 416 419 no 442237 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559304 Millerozyma farinosa CBS 7064 Fungi UP000005222 448113482, 359465351 XP_004202362.1 416 419 no 442238 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 261658 Dictyostelium fasciculatum Invertebrates 470242215, 328867976 EGG16357.1 XP_004354741.1 452 452 no 442239 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559882 Trichophyton equinum CBS 127.97 Fungi UP000009169 326482232 EGE06242.1 604 604 no 442240 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 946362 Salpingoeca sp. ATCC 50818 Invertebrates UP000007799 514686755, 326431546 EGD77116.1 XP_004990955.1 507 515 no 442241 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1055687 Trypanosoma vivax Y486 Invertebrates UP000009027 340058428 648 649 no 442242 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 890382 Albugo laibachii Nc14 Plants 325188927 625 629 no 442243 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 999810 Botryotinia fuckeliana isolate T4 Fungi UP000008177 347835202 442 455 no 442244 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 999809 Sporisorium reilianum SRZ2 Fungi UP000008867 343428937 652 653 no 442245 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5786 Dictyostelium purpureum Invertebrates UP000001064 UP000001064 330797020, 325083466 EGC36918.1 XP_003286561.1 457 458 no 442246 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559305, 5551 Trichophyton rubrum CBS 118892, Trichophyton rubrum Fungi UP000008864 327303476, 861304943 KMQ49012.1 XP_003236430.1 428 440 no 442247 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 79923 Clonorchis sinensis Invertebrates UP000008909 358340942 420 430 no 442248 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 756982 Arthrobotrys oligospora ATCC 24927 Fungi UP000008784 748511064, 345565012 EGX47968.1 XP_011123414.1 446 452 no 442249 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 112509 Hordeum vulgare subsp. vulgare Plants UP000011116 326506638 470 473 no 442250 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 590646 Candida tenuis ATCC 10573 Fungi UP000000707 575517009, 344229720 EGV61605.1 XP_006687775.1 561 563 no 442251 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 747676 Melampsora laricis-populina 98AG31 Fungi UP000001072 599366407, 328861531 EGG10634.1 XP_007406103.1 529 534 no 442252 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 759272 Chaetomium thermophilum var. thermophilum DSM 1495 Fungi UP000008066 576036804, 340966749 EGS22256.1 XP_006692275.1 546 546 no 442253 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 544711 Ajellomyces capsulatus H88 Fungi UP000008142 325093216 EGC46526.1 422 425 no 442254 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 572307 Neospora caninum Nc-Liverpool Invertebrates UP000007494 401406832, 820691069, 325117281 XP_003882865.1 551 553 no 442255 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39669, 679901 Methanosalsum zhilinae, Methanosalsum zhilinae DSM 4017 Archaea UP000006622 503665037, 335931136 AEH61677.1 WP_013899113.1 F7XMD6 F7XMD6_METZD 326 328 no 442256 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 180454 Anopheles gambiae str. PEST Invertebrates 347964779, 333466475 EAA04953.5 XP_309119.5 479 479 no 442257 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1071378 Naumovozyma dairenensis CBS 421 Fungi UP000000689 365983612, 343767406 XP_003668639.1 426 432 no 442258 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 946362 Salpingoeca sp. ATCC 50818 Invertebrates UP000007799 514690602, 326429048 EGD74618.1 XP_004992875.1 296 305 no 442259 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1095631 Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7 Fungi UP000009009 365759787 EHN01558.1 526 532 no 442260 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 647113 Methanothermococcus okinawensis IH1 Archaea UP000009296 334856755 AEH07231.1 F8AJN7 F8AJN7_METOI 329 336 no 442261 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 336722 Mycosphaerella graminicola IPO323 Fungi UP000008062 398398848, 339472763 EGP87857.1 XP_003852881.1 558 560 no 442262 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 647933 Trichophyton tonsurans CBS 112818 Fungi UP000009172 326475134 EGD99143.1 604 604 no 442263 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 61853 Nomascus leucogenys Primates UP000001073 332259200 XP_003278675.1 489 489 no 442264 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13037 Danaus plexippus Invertebrates UP000007151 357628295 EHJ77684.1 408 419 no 442265 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1033177 Aspergillus kawachii IFO 4308 Fungi UP000006812 358368919 571 571 no 442266 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1071382 Kazachstania africana CBS 2517 Fungi UP000005220 410082613, 372465474 XP_003958885.1 419 422 no 442267 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 931890 Eremothecium cymbalariae DBVPG#7215 Fungi UP000006790 363750802, 356889252 AET38801.1 XP_003645618.1 423 427 no 442268 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1068625 Trypanosoma congolense IL3000 Invertebrates UP000000702 342185363 160 162 no 442269 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1095631 Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7 Fungi UP000009009 365764500 EHN06022.1 489 495 no 442270 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 619300 Spathaspora passalidarum NRRL Y-27907 Fungi UP000000709 598071797, 344300373 EGW30694.1 XP_007376727.1 563 563 no 442271 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 684364 Batrachochytrium dendrobatidis JAM81 Fungi UP000007241 UP000007241 575478154, 328770967 EGF81008.1 XP_006678371.1 532 535 no 442272 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 301375, 1110509 Methanosaeta harundinacea, Methanosaeta harundinacea 6Ac Archaea UP000053961, UP000005877 504399202, 357209499 AET64119.1 WP_014586304.1 G7WKT6 G7WKT6_METH6 329 335 no 442273 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1071382 Kazachstania africana CBS 2517 Fungi UP000005220 410082792, 372465564 XP_003958974.1 533 539 no 442274 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 983644 Cordyceps militaris CM01 Fungi UP000001610 573986753, 346322334 EGX91933.1 XP_006671297.1 531 531 no 442275 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 693661 Archaeoglobus veneficus SNP6 Archaea UP000008136 327316897 AEA47513.1 F2KPA9 F2KPA9_ARCVS 330 335 no 442276 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 430914, 1033806 Halorhabdus tiamatea, Halorhabdus tiamatea SARL4B Archaea UP000015381 495800851, 543101342 ERJ07046.1 WP_008525430.1 U2E551 U2E551_9EURY 348 349 no 442277 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1055687 Trypanosoma vivax Y486 Invertebrates UP000009027 340052900 357 358 no 442278 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 452589 Trichoderma atroviride IMI 206040 Fungi UP000005426 358390697 EHK40102.1 534 534 no 442279 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 380704 Aspergillus niger ATCC 1015 Fungi UP000009038 350635946 EHA24307.1 547 547 no 442280 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1033177 Aspergillus kawachii IFO 4308 Fungi UP000006812 358365623 428 433 no 442281 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9103 Meleagris gallopavo Vertebrates UP000001645 326925241 XP_003208827.1 476 477 no 442282 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5480 Candida parapsilosis Fungi 354546618 420 422 no 442283 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1071378 Naumovozyma dairenensis CBS 421 Fungi UP000000689 365986378, 343768790 XP_003670021.1 572 592 no 442284 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 242507 Magnaporthe oryzae 70-15 Fungi UP000009058 389638212, 351642558 EHA50420.1 XP_003716739.1 449 457 no 442285 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9544 Macaca mulatta Primates UP000006718 UP000006718 355568068 EHH24349.1 435 452 no 442286 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 135651 Caenorhabditis brenneri Invertebrates UP000008068 341888968 EGT44903.1 461 461 no 442287 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1064592 Naumovozyma castellii CBS 4309 Fungi UP000001640 366986909, 342299084 XP_003673221.1 559 596 no 442288 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 498257 Verticillium dahliae VdLs.17 Fungi UP000001611 697089633, 346972110 EGY15562.1 XP_009657725.1 566 566 no 442289 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 413071 Trichoderma virens Gv29-8 Fungi UP000007115 358381645 EHK19320.1 G9N2L0 G9N2L0_HYPVG 532 532 no 442290 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1072681 Nanohaloarchaea archaeon G17 Archaea 358032851 EHK01482.1 H0ACI0 H0ACI0_HALSG 321 333 no 442291 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578455 Thielavia terrestris NRRL 8126 Fungi UP000008181 367048151, 347001718 AEO68119.1 XP_003654455.1 546 546 no 442292 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559304 Millerozyma farinosa CBS 7064 Fungi UP000005222 448103480, 359381467 XP_004200045.1 584 585 no 442293 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1095631 Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7 Fungi UP000009009 365765091 EHN06605.1 423 425 no 442294 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 387343, 797210 Halopiger xanaduensis, Halopiger xanaduensis SH-6 Archaea UP000006794 503646745, 336254703, 335338692 AEH37931.1 WP_013880821.1, YP_004597810.1 F8D839 F8D839_HALXS 349 349 no 442295 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1104324 Pyrobaculum sp. 1860 Archaea UP000005867 504054790, 374327010, 356642279 AET32958.1 WP_014288784.1, YP_005085210.1 G7VFF2 G7VFF2_9CREN 302 302 no 442296 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 877455 Methanobacterium sp. 17A1 Archaea UP000007490 503409140, 325329388 ADZ08450.1 WP_013643801.1 F0T7W3 F0T7W3_METLA 336 337 no 442297 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 771870 Sordaria macrospora k-hell Fungi UP000001881 336269296, 380089196 XP_003349409.1 599 603 no 442298 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 619300 Spathaspora passalidarum NRRL Y-27907 Fungi UP000000709 598068111, 344303095 EGW33369.1 XP_007374884.1 417 423 no 442299 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 336722 Mycosphaerella graminicola IPO323 Fungi UP000008062 398410477, 339476473 EGP91564.1 XP_003856588.1 451 469 no 442300 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5480 Candida parapsilosis Fungi 354547707 538 541 no 442301 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1111107, 671065 Metallosphaera yellowstonensis, Metallosphaera sp. MK1 Archaea 496366791, 373523967 EHP68887.1 WP_009075781.1 H2C9R1 H2C9R1_9CREN 329 331 no 442302 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 274 276 no 442303 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 937775 Methanoplanus limicola DSM 2279 Archaea UP000005741 373906988 EHQ35092.1 H1YYJ4 H1YYJ4_9EURY 325 493 no 442304 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 227321 Aspergillus nidulans FGSC A4 Fungi UP000000560 UP000000560 67540226, 40739477, 259479503 EAA58667.1 XP_663887.1 Q5AZJ7 DPH1_EMENI 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 8690704 185 193 no 442305 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39152, 267377 Methanococcus maripaludis, Methanococcus maripaludis S2 Archaea UP000000590 499483492, 45047311 WP_011170132.1 Q6M0T1 Q6M0T1_METMP fig|267377.1.peg.188 304 309 no 442306 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2208, 1434109, 269797 Methanosarcina barkeri, Methanosarcina barkeri str. Wiesmoor, Methanosarcina barkeri str. Fusaro Archaea UP000033038, UP000008156 499625891, 805401830, 72396306 AKB52350.1, AAZ70579.1 WP_011306625.1 A0A0E3QPD2, Q46C13 A0A0E3QPD2_METBA, Q46C13_METBF fig|269797.3.peg.2034 330 335 no 442307 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 858893 Exophiala dermatitidis NIH/UT8656 Fungi UP000007304 684175335, 378734615 EHY61074.1 XP_009161535.1 436 445 no 442308 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9544 Macaca mulatta Primates UP000006718 UP000006718 380794917 AFE69334.1 424 439 no 442309 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 31271 Plasmodium chabaudi chabaudi Invertebrates 70922790, 56507309 XP_734505.1 195 200 no 442310 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6182 Schistosoma japonicum Invertebrates 76157788 AAX28604.2 390 395 no 442311 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2265, 523849 Thermococcus litoralis, Thermococcus litoralis DSM 5473 Archaea UP000015502 490169007, 374742571 EHR78962.1 WP_004067650.1 H3ZM18 H3ZM18_THELN 339 345 no 442312 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 416 420 no 442313 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 352472, 44689 Dictyostelium discoideum AX4, Dictyostelium discoideum Invertebrates UP000002195 UP000002195 66809913, 60467284, 74854314 EAL65317.1 XP_638680.1 Q54PW5 DPH1_DICDI 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 472 472 no 442314 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 284811, 1034331 Ashbya gossypii ATCC 10895, Ashbya gossypii FDAG1 Fungi UP000000591 UP000000591, UP000032842 45187644, 374107080, 44982405, 74694564 AEY95988.1, AAS51691.1 NP_983867.1 Q75AZ9 DPH1_ASHGO 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 6619473 fig|33169.1.peg.1512 424 426 no 442315 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 185431 Trypanosoma brucei TREU927 Invertebrates UP000008524 UP000008524 71754863, 70833732 EAN79234.1 XP_828346.1 655 657 no 442316 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 82076, 263820 Picrophilus torridus, Picrophilus torridus DSM 9790 Archaea UP000000438 499490591, 48430150 AAT43015.1 WP_011177231.1 Q6L1Y7 Q6L1Y7_PICTO fig|263820.1.peg.430 317 322 no 442317 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 339860 Methanosphaera stadtmanae DSM 3091 Archaea UP000001931 84373634 ABC57904.1 Q2NE49 Q2NE49_METST fig|339860.6.peg.1470 336 337 no 442318 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 227321 Aspergillus nidulans FGSC A4 Fungi UP000000560 UP000000560 84028905 Q5AZJ7 DPH1_EMENI 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 8690704 427 431 no 442319 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 213185, 647171 Methanotorris formicicus, Methanotorris formicicus Mc-S-70 Archaea 494103923, 373559398 EHP85697.1 WP_007044710.1 H1KZQ6 H1KZQ6_9EURY 317 319 no 442320 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1136231 Candida orthopsilosis Co 90-125 Fungi UP000005018 448512459, 380351082 XP_003866744.1 420 424 no 442321 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 99883 Tetraodon nigroviridis Vertebrates UP000007303 47227763 434 439 no 442322 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 367110, 5141 Neurospora crassa OR74A, Neurospora crassa Fungi UP000001805 UP000001805, UP000053122 758990685, 758990683, 553138430, 553138429, 74617621, 38524208 ESA43686.1, ESA43685.1 XP_011393623.1, XP_011393622.1 Q7SC98 DPH1_NEUCR 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 8964910 fig|5141.1.peg.7481 448 459 no 442323 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7955 Danio rerio Vertebrates UP000000437 UP000000437 62955695, 62202406, 82178163 AAH92989.1 NP_001017861.1 Q567W6 DPH1_DANRE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 332 381 no 442324 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 353152 Cryptosporidium parvum Iowa II Invertebrates UP000006726 66359418, 46228104 EAK89003.1 XP_626887.1 549 551 no 442325 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8355 Xenopus laevis Vertebrates 49119420 AAH73057.1 Q6GPQ5 DPH1_XENLA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 442 449 no 442326 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 858893 Exophiala dermatitidis NIH/UT8656 Fungi UP000007304 684157096, 378725506 EHY51965.1 XP_009152426.1 561 562 no 442327 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2285, 1028567, 1028566, 330779 Sulfolobus acidocaldarius, Sulfolobus acidocaldarius Ron12/I, Sulfolobus acidocaldarius N8, Sulfolobus acidocaldarius DSM 639 Archaea UP000065473, UP000011280, UP000011281, UP000001018 499596361, 449036997, 449034721, 68566665 AGE72422.1, AGE70147.1, AAY79594.1 WP_011277095.1 A0A0U3GU07, M1IUZ3, Q4JC85, M1IMH3 A0A0U3GU07_9CREN, M1IUZ3_9CREN, Q4JC85_SULAC, M1IMH3_9CREN fig|330779.3.peg.440 332 334 no 442328 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9031 Gallus gallus Vertebrates UP000000539 UP000000539 82080908, 53136670 Q5ZHX9 DPH1_CHICK 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 406 409 no 442329 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9615 Canis lupus familiaris Mammals UP000002254 UP000002254 73978015 XP_532611.2 fig|9615.3.peg.6037 487 487 no 442330 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 284591 Yarrowia lipolytica CLIB122 Fungi UP000001300 UP000001300 50556652, 74632362, 49651604 XP_505734.1 Q6C0S8 DPH1_YARLI 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 6604648 436 439 no 442331 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 228908, 160232 Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans Archaea UP000000578 41615020, 499466580, 40068744 AAR39079.1 NP_963518.1, WP_011153220.1 Q74NE7 Q74NE7_NANEQ 544234 fig|228908.1.peg.224 288 296 no 442332 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 99883 Tetraodon nigroviridis Vertebrates UP000007303 47206297 60 154 no 442333 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 294381, 885318, 885319 Entamoeba histolytica HM-1:IMSS, Entamoeba histolytica HM-1:IMSS-A, Entamoeba histolytica HM-1:IMSS-B Invertebrates UP000013105, UP000030781 67475140, 480524136, 459658905, 56470225 ENY63200.1, EMH74656.1, EAL47902.1 XP_653288.1 337 344 no 442334 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 337893 uncultured euryarchaeote Alv-FOS4 Archaea 71483081 AAZ32514.1 Q3SA68 Q3SA68_9EURY 324 326 no 442335 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 559292, 1294355, 889517, 4932 Saccharomyces cerevisiae S288c, Saccharomyces cerevisiae YJM1381, Saccharomyces cerevisiae CEN.PK113-7D, Saccharomyces cerevisiae Fungi UP000002311 UP000002311, UP000033179, UP000013192 6322088, 765834003, 392298816, 23332110, 285812551, 731852, 558703 AJR47691.1, EIW09912.1, AAN27051.1 NP_012163.1 P40487 DPH1_YEAST 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 9048023, 6583503 fig|559292.3.peg.2695, fig|4932.3.peg.1689 423 425 no 442336 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 353151 Cryptosporidium hominis TU502 Invertebrates 67619235 XP_667633.1 480 497 no 442337 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2237, 272569, 662475 Haloarcula marismortui ATCC 43049, Haloarcula californiae ATCC 33799 Archaea UP000001169 494348153, 55377297, 445763094, 55230022 EMA14298.1, AAV45441.1 WP_007189913.1, YP_135147.1 M0K0J8, Q5V4W1 M0K0J8_9EURY, Q5V4W1_HALMA 747017 fig|272569.1.peg.405, fig|662475.4.peg.3838 347 348 no 442338 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 353153, 5693 Trypanosoma cruzi strain CL Brener, Trypanosoma cruzi Invertebrates UP000002296, UP000008313 71667955, 70886285 EAN99071.1 XP_820922.1 619 621 no 442339 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2257, 348780 Natronomonas pharaonis, Natronomonas pharaonis DSM 2160 Archaea UP000002698 499642556, 76802217, 76558082 WP_011323290.1, YP_327225.1 1115997 fig|348780.3.peg.1562 351 351 no 442340 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 62734209 AAX96318.1 376 378 no 442341 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1136231, 273371 Candida orthopsilosis Co 90-125, Candida orthopsilosis Fungi UP000005018 448530024, 380354321 XP_003869967.1 537 574 no 442342 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 237631 Ustilago maydis 521 Fungi UP000000561 UP000000561 758978727, 757946590, 74702098 KIS69059.1 XP_011389413.1 Q4PA25 DPH1_USTMA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 609 609 no 442343 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 237561 Candida albicans SC5314 Fungi UP000000559 UP000030576 68490548, 68490517, 46432175, 46432159 EAK91672.1, EAK91657.1 XP_710900.1, XP_710915.1 Q59MG1 DPH1_CANAL 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 206 214 no 442344 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 237561 Candida albicans SC5314 Fungi UP000000559 UP000030576 68490550, 68490519, 46432176, 46432160 EAK91673.1, EAK91658.1 XP_710901.1, XP_710916.1 Q59MG1 DPH1_CANAL 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 199 207 no 442345 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 353151 Cryptosporidium hominis TU502 Invertebrates 67623797 XP_668181.1 549 551 no 442346 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5823, 5821 Plasmodium berghei str. ANKA, Plasmodium berghei Invertebrates UP000007720, UP000069549 68074791, 56500030 XP_679312.1 622 622 no 442347 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 31271 Plasmodium chabaudi chabaudi Invertebrates 70922026, 56506805 XP_734245.1 196 198 no 442348 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 333668, 5875 Theileria parva strain Muguga, Theileria parva Invertebrates UP000001949 71033131, 68353164 EAN33924.1 XP_766207.1 395 670 no 442349 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 560 574 no 442350 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 333668, 5875 Theileria parva strain Muguga, Theileria parva Invertebrates UP000001949 71030576, 68351886 EAN32647.1 XP_764930.1 424 428 no 442351 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 284590, 28985 Kluyveromyces lactis NRRL Y-1140, Kluyveromyces lactis Fungi UP000000598 50310481, 74605394, 49644396 XP_455260.1 Q6CLC9 DPH1_KLULA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 6596755 418 422 no 442352 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 944018 Nematocida sp. 1 ERTm2 Fungi UP000005622 378755925 EHY65950.1 419 430 no 442353 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 284593, 5478 Candida glabrata CBS 138, Candida glabrata Fungi UP000002428, UP000054886 50288109, 74610149, 49525791 XP_446483.1 Q6FTG1 DPH1_CANGA 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 6615154 422 428 no 442354 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 185431, 5691 Trypanosoma brucei TREU927, Trypanosoma brucei Invertebrates UP000008524 UP000008524 72387203, 70800558, 62358887 AAZ10467.1, AAX79339.1 XP_844026.1 356 357 no 442355 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 237561 Candida albicans SC5314 Fungi UP000000559 UP000030576 84028904 Q59MG1 DPH1_CANAL 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 418 426 no 442356 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 229533, 5518 Gibberella zeae PH-1, Gibberella zeae Fungi UP000009057, UP000022177 758187895, 558855760, 699041617, 84028906 ESU05843.1 XP_011316328.1 Q4IQ72 DPH1_GIBZE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 8841033 fig|229533.1.peg.636 454 462 no 442357 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5823, 5821 Plasmodium berghei str. ANKA, Plasmodium berghei Invertebrates UP000007720, UP000069549 68071287, 56497718 XP_677557.1 305 310 no 442358 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 418459 Puccinia graminis f. sp. tritici CRL 75-36-700-3 Fungi UP000008783 UP000008783 403172608, 375169919 EFP87331.2 XP_003331750.2 545 547 no 442359 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 323259 Methanospirillum hungatei JF-1 Archaea UP000001941 88189313 ABD42310.1 Q2FSD1 Q2FSD1_METHJ fig|323259.5.peg.2741 294 295 no 442360 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 31271 Plasmodium chabaudi chabaudi Invertebrates 70940547, 56518551 XP_740675.1 543 543 no 442361 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 311400, 69014 Thermococcus kodakarensis, Thermococcus kodakarensis KOD1 Archaea UP000000536 UP000000536 499570095, 57160187 WP_011250878.1 Q5JET7 Q5JET7_THEKO fig|69014.3.peg.1778 335 341 no 442362 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 353153, 5693 Trypanosoma cruzi strain CL Brener, Trypanosoma cruzi Invertebrates UP000002296, UP000008313 71396749, 70862845 EAN80969.1 XP_802415.1 266 268 no 442363 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9541 Macaca fascicularis Primates UP000009130 548961887, 67971996 NP_001272089.1 113 121 no 442364 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1170320, 859350 Candidatus Nitrosopumilus salaria, marine archaeal group 1 strain BD31 Archaea 495575507, 386806179 EIJ65657.1 WP_008300086.1 I3D1R4 I3D1R4_9ARCH 324 331 no 442365 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 418459 Puccinia graminis f. sp. tritici CRL 75-36-700-3 Fungi UP000008783 UP000008783 403169387, 375167937 EFP84418.2 XP_003328837.2 586 587 no 442366 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 31271 Plasmodium chabaudi chabaudi Invertebrates 70947267, 56522680 XP_743266.1 470 475 no 442367 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 99883 Tetraodon nigroviridis Vertebrates UP000007303 47225188 520 520 no 442368 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6182 Schistosoma japonicum Invertebrates 76154322 AAX25812.2 223 229 no 442369 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 259564 Methanococcoides burtonii DSM 6242 Archaea UP000001979 91712419 ABE52346.1 Q12W30 Q12W30_METBU fig|259564.8.peg.1366 330 331 no 442370 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6182 Schistosoma japonicum Invertebrates 56753621 AAW25013.1 172 189 no 442371 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 99007, 698757 Pyrobaculum oguniense, Pyrobaculum oguniense CH Archaea UP000009062 504112425, 379003816, 375159269 AFA38881.1 WP_014346411.1, YP_005259488.1 H6Q9P7 H6Q9P7_PYROT 142 303 no 442372 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 944018 Nematocida sp. 1 ERTm2 Fungi UP000005622 378754536 EHY64567.1 367 373 no 442373 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6182 Schistosoma japonicum Invertebrates 76156393 AAX27600.2 305 323 no 442374 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 353154, 5874 Theileria annulata strain Ankara, Theileria annulata Invertebrates UP000001950 84995266, 65302516 XP_952355.1 423 428 no 442380 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 120017 Ustilago hordei Fungi 388857861 656 657 no 442381 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 498 578 no 442382 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 721885 Stereum hirsutum FP-91666 SS1 Fungi UP000053927 618806462, 389743633 EIM84817.1 XP_007305986.1 510 510 no 442383 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10029 Cricetulus griseus Rodents UP000030759 354490345 XP_003507319.1 418 438 no 442384 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 229731, 358396 Halobiforma lacisalsi, Halobiforma lacisalsi AJ5 Archaea 494238978, 445780391 EMA31279.1 WP_007142613.1 M0LFR3 M0LFR3_9EURY 353 353 no 442385 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 274854 uncultured marine group II euryarchaeote Archaea 374724135 EHR76215.1 367 369 no 442386 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 34638 Metaseiulus occidentalis Invertebrates 391334445 XP_003741614.1 481 489 no 442387 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 395 404 no 442388 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 246410 Coccidioides immitis RS Fungi UP000001261 119178293, 767018915 EAS29250.3 XP_001240833.1 600 600 no 442389 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8128 Oreochromis niloticus Vertebrates UP000005207 348538424 XP_003456691.1 493 494 no 442390 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4932, 559292 Saccharomyces cerevisiae, Saccharomyces cerevisiae S288c Fungi UP000002311 UP000002311 473145 P32461 DPH2_YEAST 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} 6584073 fig|4932.3.peg.3707, fig|559292.3.peg.3220 271 277 no 442391 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 717982 Auricularia delicata TFB-10046 SS5 Fungi UP000006514 598040499, 393234783 EJD42343.1 XP_007349622.1 474 474 no 442392 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 15368 Brachypodium distachyon Plants UP000008810 UP000008810 357156927 XP_003577623.1 505 507 no 442393 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 97393, 333146 Ferroplasma acidarmanus, Ferroplasma acidarmanus fer1 Archaea UP000014660 497572575, 514837634 AGO60711.1 WP_009886759.1 S0AP85 S0AP85_FERAC fig|97393.1.peg.1601 324 334 no 442394 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 502 503 no 442395 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 132113 Bombus impatiens Invertebrates 815904659, 815904656, 350406247 XP_012238236.1, XP_012238235.1, XP_003487706.1 445 452 no 442396 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9305 Sarcophilus harrisii Mammals UP000007648 395530344 XP_003767256.1 459 532 no 442397 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 671144 Wallemia sebi CBS 633.66 Fungi UP000005242 588253456, 388583783 EIM24084.1 XP_006955910.1 546 557 no 442398 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3847 Glycine max Plants UP000008827 UP000008827 356555374 XP_003546007.1 485 485 no 442399 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10090 Mus musculus Rodents UP000000589 UP000000589 28279920 AAH44663.1 Q5NCQ5 DPH1_MOUSE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} fig|10090.3.peg.24711 419 436 no 442400 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 456 456 no 442401 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1185654 Pyrococcus furiosus COM1 Archaea UP000006216 393189161 AFN03859.1 I6TWT2 I6TWT2_9EURY 335 343 no 442402 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1111077 Claviceps purpurea 20.1 Fungi UP000016801 399169147 552 552 no 442403 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7209 Loa loa Invertebrates UP000007040 393908160 EFO23169.2 471 474 no 442404 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 28892 Methanofollis liminatans DSM 4140 Archaea UP000005095 395441799 EJG06556.1 J0RYC9 J0RYC9_9EURY 313 320 no 442405 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 481 481 no 442406 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1071380 Tetrapisispora blattae CBS 6284 Fungi UP000002866 444323701, 387515538 XP_004182491.1 529 529 no 442407 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 502 604 no 442408 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9606 Homo sapiens Primates UP000005640 UP000005640 3170458 AAC18086.1 Q9BQC3 DPH2_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} fig|9606.3.peg.1024 489 489 no 442409 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1183377 Pyrococcus sp. ST04 Archaea UP000006467 504547024, 388249748 AFK22601.1 WP_014734126.1 I3REE1 I3REE1_9EURY 335 344 no 442410 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7029 Acyrthosiphon pisum Invertebrates UP000007819 193599140 XP_001949323.1 410 412 no 442411 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578456 Tremella mesenterica DSM 1558 Fungi UP000054539 589272302, 392579237 EIW72364.1 XP_007001881.1 497 498 no 442412 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7719 Ciona intestinalis Invertebrates UP000008144 UP000008144 198422674 XP_002130985.1 417 420 no 442413 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1124627 Dekkera bruxellensis AWRI1499 Fungi UP000004997 385305769 EIF49718.1 389 394 no 442414 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7668 Strongylocentrotus purpuratus Invertebrates UP000007110 UP000007110 780142055, 115712687 XP_011680796.1, XP_786110.2 552 552 no 442415 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9615 Canis lupus familiaris Mammals UP000002254 UP000002254 345780917 XP_003432052.1 261 261 no 442416 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6182 Schistosoma japonicum Invertebrates 226466508 510 514 no 442417 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 246409 Rhizopus oryzae RA 99-880 Fungi UP000009138 384483532 EIE75712.1 538 538 no 442418 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 655819 Beauveria bassiana ARSEF 2860 Fungi UP000002762 667643091, 400602830 EJP70428.1 XP_008593377.1 528 528 no 442419 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1197718, 1160506 Aspergillus oryzae 100-8, Aspergillus oryzae 3.042 Fungi UP000026920, UP000002812 635504963, 391871193 KDE77042.1, EIT80358.1 572 573 no 442420 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 398 405 no 442421 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10090 Mus musculus Rodents UP000000589 UP000000589 21411048 AAH31124.1 Q9CR25 DPH2_MOUSE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 {ECO:0000305} fig|10090.3.peg.10210 489 489 no 442422 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 484 563 no 442423 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 425011 Aspergillus niger CBS 513.88 Fungi UP000006706 317029628 XP_001392012.2 557 557 no 442424 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1201294 Methanoculleus bourgensis MS2 Archaea UP000009007 396938211 I7KBK5 I7KBK5_METBM 313 317 no 442425 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 493 496 no 442426 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 163003 Thermococcus sp. CL1 Archaea UP000006064 504601474, 390519208 AFL94940.1 WP_014788576.1 I3ZTA6 I3ZTA6_9EURY 336 344 no 442427 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9483 Callithrix jacchus Primates UP000008225 390480648 XP_003735971.1 489 489 no 442428 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 478 479 no 442429 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10224 Saccoglossus kowalevskii Invertebrates 291237135 XP_002738492.1 462 467 no 442430 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 523841 Haloferax mediterranei ATCC 33500 Archaea UP000011603 389847171, 631803530, 388244477 AHZ21226.1, AFK19423.1 YP_006349410.1 I3R5B3 I3R5B3_HALMT 343 344 no 442431 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 272844 Pyrococcus abyssi GE5 Archaea UP000009139 380741909 G8ZJT4 G8ZJT4_PYRAB 335 356 no 442432 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10090 Mus musculus Rodents UP000000589 UP000000589 148698585 EDL30532.1 414 414 no 442433 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 66420 Papilio xuthus Invertebrates UP000053268 389612319 447 454 no 442434 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7425 Nasonia vitripennis Invertebrates UP000002358 156537656 XP_001607847.1 479 482 no 442435 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 246410 Coccidioides immitis RS Fungi UP000001261 119190329, 767020505 EAS34188.3 XP_001245771.1 430 439 no 442436 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 456 461 no 442437 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 490 491 no 442438 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 683846, 1163730 Fervidicoccus fontis, Fervidicoccus fontis Kam940 Archaea UP000007391 504371137, 385806144, 383796007 AFH43090.1 WP_014558239.1, YP_005842542.1 I0A283 I0A283_FERFK 341 342 no 442439 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 399 404 no 442440 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13489 Dicentrarchus labrax Vertebrates 317419745 492 492 no 442441 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 693851, 1210908 Haloferax sp. B-1, Halogranum salarium B-1 Archaea 496767056, 399240181 EJN61106.1 WP_009365491.1 J3JHM4 J3JHM4_9EURY 347 348 no 442442 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 421 423 no 442443 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 30611 Otolemur garnettii Primates UP000005225 395857758 XP_003801251.1 487 487 no 442444 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7029 Acyrthosiphon pisum Invertebrates UP000007819 193596645 XP_001944182.1 413 417 no 442445 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 451 539 no 442446 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 400682 Amphimedon queenslandica Invertebrates UP000007879 340372463 XP_003384763.1 476 479 no 442447 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9597, 9598 Pan paniscus, Pan troglodytes Primates UP000002277 UP000065018, UP000002277 397483375, 410331743 JAA34818.1 XP_003812878.1 489 489 no 442448 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 741705 Coniophora puteana RWD-64-598 SS2 Fungi UP000053558 628847462, 392588656 EIW77988.1 XP_007772270.1 515 517 no 442449 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8364 Xenopus (Silurana) tropicalis Vertebrates UP000008143 UP000008143 301603947 XP_002931628.1 478 478 no 442450 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 492 570 no 442451 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1071380 Tetrapisispora blattae CBS 6284 Fungi UP000002866 444322087, 387514744 XP_004181699.1 423 424 no 442452 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 732165 Dichomitus squalens LYAD-421 SS1 Fungi UP000053319 597988515, 395329685 EJF62071.1 XP_007365326.1 507 507 no 442453 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 61853 Nomascus leucogenys Primates UP000001073 332259202 XP_003278676.1 261 261 no 442454 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9646 Ailuropoda melanoleuca Mammals UP000008912 301780362 XP_002925597.1 489 489 no 442455 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 80884 Colletotrichum higginsianum Fungi 380481934 520 520 no 442456 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7370 Musca domestica Invertebrates 399945106 AFP62987.1 433 442 no 442457 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 764103 Mixia osmundae IAM 14324 Fungi UP000027399 658167793, 358056859 KEI42502.1 G7E328 G7E328_MIXOS 495 495 no 442458 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 59729 Taeniopygia guttata Vertebrates UP000007754 224057760 XP_002189199.1 477 478 no 442459 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1184251 Thermogladius cellulolyticus 1633 Archaea UP000005270 388525678 AFK50876.1 I3TDN8 I3TDN8_THEC1 333 336 no 442460 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 88723, 406552, 1230459 Natrinema sp. J7, Natrinema gari JCM 14663 Archaea UP000006507 495733790, 397774765, 445622906, 397683858 ELY76347.1, AFO58235.1 WP_008458369.1, YP_006542311.1 L9YS90, I7BYX6 L9YS90_9EURY, I7BYX6_NATSJ 349 349 no 442461 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 246409 Rhizopus oryzae RA 99-880 Fungi UP000009138 384500988 EIE91479.1 431 432 no 442462 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 574566 Coccomyxa sp. C-169 Plants UP000007264 545355907, 384245686 EIE19179.1 XP_005643723.1 389 397 no 442463 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7463 Apis florea Invertebrates 380018103 XP_003692975.1 456 473 no 442464 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 394 409 no 442465 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 717944 Trametes versicolor FP-101664 SS1 Fungi UP000054317 636626313, 392559547 EIW52731.1 XP_008044291.1 511 516 no 442466 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 34638 Metaseiulus occidentalis Invertebrates 391339966 XP_003744317.1 405 406 no 442467 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 32630 synthetic construct Synthetic 60652597, 60652595, 30584261 AAX28993.1, AAX28992.1, AAP36379.1 489 490 no 442468 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7209 Loa loa Invertebrates UP000007040 393912225 EFO22230.2 386 392 no 442469 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 694068 Fomitiporia mediterranea MF3/22 Fungi UP000053630 595785544, 393212874 EJC98372.1 XP_007271315.1 510 512 no 442470 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 574566 Coccomyxa sp. C-169 Plants UP000007264 545366940, 384250316 EIE23796.1 XP_005648340.1 526 528 no 442471 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7425 Nasonia vitripennis Invertebrates UP000002358 644991907, 644991905, 644991903 XP_008202717.1, XP_008202716.1, XP_008202715.1 437 437 no 442472 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1109443 Piriformospora indica DSM 11827 Fungi UP000007148 353234391 505 511 no 442473 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13616 Monodelphis domestica Mammals UP000002280 UP000002280 334321572 XP_001376280.2 495 495 no 442474 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 386 483 no 442475 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 741275 Punctularia strigosozonata HHB-11173 SS5 Fungi UP000054196 599122204, 390595068 EIN04475.1 XP_007388270.1 505 505 no 445789 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9555 Papio anubis Primates UP000028761 402854280 XP_003891803.1 489 489 yes 445790 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 226230 Saccharomyces kudriavzevii IFO 1802 Fungi UP000002753 401839396 EJT42646.1 526 532 yes 445791 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 39432 Saimiri boliviensis boliviensis Primates 403291879 XP_003936989.1 489 489 yes 445792 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1071383 Kazachstania naganishii CBS 8797 Fungi UP000006310 403216136 543 550 yes 445793 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 261 261 no 445794 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1186058 Trichosporon asahii var. asahii CBS 2479 Fungi UP000002748 401884660 EJT48810.1 541 557 yes 445795 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 644352 Gaeumannomyces graminis var. tritici R3-111a-1 Fungi UP000006039 685394500, 402085206 EJT80104.1 XP_009216113.1 J3NFR4 J3NFR4_GAGT3 582 582 yes 445796 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 745407 Dacryopinax sp. DJM-731 SS1 Fungi UP000030653 402224088 EJU04151.1 509 509 yes 445797 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 599839 Fibroporia radiculosa Fungi UP000006352 807746753, 403412188 XP_012178171.1 443 452 no 445798 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6293 Wuchereria bancrofti Invertebrates UP000004810 402589597 EJW83529.1 461 461 yes 445799 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1160507 Saccharomyces arboricola H-6 Fungi UP000006968 748452059, 401624959 EJS42993.1 XP_011104212.1 528 534 yes 452255 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 401 406 yes 452256 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 338191, 1229908 Candidatus Nitrosopumilus koreensis AR1 Archaea UP000006101 504776835, 407463183, 407046805 AFS81558.1 WP_014963937.1, YP_006774500.1 K0B5U1 K0B5U1_9ARCH 323 331 no 452257 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 54076 Thermococcus zilligii Archaea 498163940 WP_010478096.1 338 352 no 452258 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1028729 Fusarium pseudograminearum CS3096 Fungi UP000007978 685867615, 408391070 EKJ70454.1 XP_009260840.1 534 535 yes 452259 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1126212 Macrophomina phaseolina MS6 Fungi UP000007129 407918240 EKG11512.1 587 589 yes 452260 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29159 Crassostrea gigas Invertebrates UP000005408 762123194, 762123192, 762123190, 405971376 EKC36215.1 XP_011444569.1, XP_011444568.1, XP_011444567.1 494 497 yes 452261 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 31033 Takifugu rubripes Vertebrates UP000005226 UP000005226 410926627 XP_003976779.1 491 491 yes 452262 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 489 489 yes 452263 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2162, 1204725 Methanobacterium formicicum, Methanobacterium formicicum DSM 3637 Archaea UP000062768, UP000007360 490128963, 407816242 EKF86804.1 WP_004029372.1 K2REK3 K2REK3_METFO 328 329 no 452264 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29159 Crassostrea gigas Invertebrates UP000005408 405951039 EKC18986.1 375 380 yes 452265 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 597362 Agaricus bisporus var. burnettii JB137-S8 Fungi UP000008493 597990839, 409076804 EKM77173.1 XP_007332170.1 K5X213 K5X213_AGABU 516 516 yes 452266 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 497727, 1237085 Candidatus Nitrososphaera gargensis, Candidatus Nitrososphaera gargensis Ga9.2 Archaea UP000008037 504831151, 408403382, 408363978 AFU57708.1 WP_015018253.1, YP_006861365.1 K0IFW9 K0IFW9_NITGG 329 334 no 452267 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1041607 Wickerhamomyces ciferrii Fungi 754410542, 406604873 XP_011274453.1 585 1581 yes 452268 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 420950, 1094980 Methanolobus psychrophilus, Methanolobus psychrophilus R15 Archaea UP000000459 504866918, 409170439 AFV24314.1 WP_015054020.1 K4MG95 K4MG95_9EURY 330 332 no 452269 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 85056 Trypanosoma cruzi marinkellei Invertebrates UP000007350 407410644 EKF33006.1 357 361 yes 452270 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 332168, 1132509 Halococcus hamelinensis, Halococcus hamelinensis 100A6 Archaea 494967490, 445787346 EMA38090.1 WP_007693516.1 M0M140 M0M140_9EURY 343 344 no 452271 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1072389 Marssonina brunnea f. sp. 'multigermtubi' MB_m1 Fungi UP000006753 597580365, 406863834 EKD16881.1 XP_007293239.1 429 440 yes 452272 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 41875 Bathycoccus prasinos Plants 612398739, 412986703 XP_007514889.1 596 598 yes 452273 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1072389 Marssonina brunnea f. sp. 'multigermtubi' MB_m1 Fungi UP000006753 597588167, 406859618 EKD12682.1 XP_007297140.1 667 696 yes 452274 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 235443 Cryptococcus neoformans var. grubii H99 Fungi UP000010091 799345673, 405123685 AFR98449.1 XP_012053213.1 514 514 yes 452275 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9598 Pan troglodytes Primates UP000002277 UP000002277 694885487, 410296694, 410255688, 410210792 JAA26947.1, JAA15811.1, JAA02615.1 XP_009454092.1 489 489 yes 452276 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1220162 Trichosporon asahii var. asahii CBS 8904 Fungi UP000006757 406694250 EKC97581.1 577 582 yes 452277 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1220534 Methanobacterium sp. Maddingley MBC34 Archaea 495791620, 410597319 EKQ51946.1 WP_008516199.1 K6TWK7 K6TWK7_9EURY 328 329 no 452278 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 650164 Phanerochaete carnosa HHB-10118-sp Fungi UP000008370 599397247, 409041646 EKM51131.1 XP_007400287.1 496 497 yes 454962 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9938, 9940 Ovis aries musimon, Ovis aries Mammals UP000002356 803254535, 426215364 XP_011987221.1, XP_004001942.1 489 489 yes 454963 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1170229, 1170230 Penicillium digitatum PHI26, Penicillium digitatum Pd1 Fungi UP000009882, UP000009886 425771090, 425769428 EKV09544.1, EKV07921.1 568 569 yes 454964 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9430 Desmodus rotundus Mammals 417410537 JAA51740.1 397 418 yes 454965 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 905079 Guillardia theta CCMP2712 Plants UP000011087 551635391, 428164527 EKX33549.1 XP_005820529.1 430 509 no 454966 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1170229, 1170230 Penicillium digitatum PHI26, Penicillium digitatum Pd1 Fungi UP000009882, UP000009886 425766794, 425765363 EKV05391.1, EKV04061.1 432 435 yes 454967 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 419 651 yes 454968 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 72859 Rhipicephalus pulchellus Invertebrates 427796073 JAA63488.1 421 435 yes 454969 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 905079 Guillardia theta CCMP2712 Plants UP000011087 551642377, 428168056 EKX37006.1 XP_005823986.1 398 402 yes 454970 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9595 Gorilla gorilla gorilla Primates UP000001519 426329338 XP_004025698.1 489 489 yes 454971 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 936046 Agaricus bisporus var. bisporus H97 Fungi UP000010818 568443726, 426192251 EKV42188.1 XP_006457044.1 516 516 yes 454972 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9595 Gorilla gorilla gorilla Primates UP000001519 426329340 XP_004025699.1 261 261 no 454973 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 200415, 1056495 Caldisphaera lagunensis, Caldisphaera lagunensis DSM 15908 Archaea UP000010469 505045679, 429133872 AFZ70884.1 WP_015232781.1 L0ABT2 L0ABT2_CALLD 326 345 no 457183 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29288, 694430 Natronococcus occultus, Natronococcus occultus SP4 Archaea UP000010878 505133844, 435847040, 433673308 AGB37500.1 WP_015320946.1, YP_007309290.1 L0JYW9 L0JYW9_9EURY 348 349 no 457184 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 387341, 797302 Halovivax ruber, Halovivax ruber XH-70 Archaea UP000010846 505113513, 433638338, 433290142 AGB15965.1 WP_015300615.1, YP_007284098.1 L0I8P3 L0I8P3_HALRX 353 354 no 457185 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1143193, 1143189 Magnaporthe oryzae P131, Magnaporthe oryzae Y34 Fungi UP000011085, UP000011086 440481848, 440475587 ELQ62385.1, ELQ44256.1 673 938 yes 457186 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1257118 Acanthamoeba castellanii str. Neff Invertebrates UP000011083 470530459, 440804625 ELR25502.1 XP_004368257.1 533 552 yes 457187 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9402 Pteropus alecto Mammals UP000010552 586552894, 431910034 ELK13121.1 XP_006911462.1 485 485 yes 457188 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 673860 Aciduliprofundum sp. MAR08-339 Archaea UP000010814 505095967, 432135176 AGB04445.1 WP_015283069.1 L0HK73 L0HK73_ACIS0 320 323 no 457189 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 225400 Myotis davidii Mammals UP000010556 584085916, 432104532 ELK31150.1 XP_006762689.1 489 489 yes 457190 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 34613 Ixodes ricinus Invertebrates 442752405 JAA68362.1 483 488 yes 457191 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 882104, 593750 Methanoregula formicicum, Methanoregula formicicum SMSP Archaea UP000010824 505097509, 432136720 AGB01647.1 WP_015284611.1 L0HA72 L0HA72_METFS 310 315 no 457192 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 658429 Geomyces destructans 20631-21 Fungi UP000011064 831348277, 440632669 ELR02588.1 XP_012743984.1 431 441 yes 457193 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 43346, 72004 Bison bison bison, Bos grunniens mutus Mammals 742213474, 555990339, 440896229 ELR48216.1 XP_010860898.1, XP_005906964.1 489 489 yes 457194 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8090 Oryzias latipes Vertebrates UP000001038 432927333 XP_004080974.1 492 492 yes 457195 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 867904 Methanomethylovorans hollandica DSM 15978 Archaea UP000010866 433662971 AGB50397.1 L0KY79 L0KY79_METHD 329 330 no 457196 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 658429 Geomyces destructans 20631-21 Fungi UP000011064 831352659, 440636089 ELR06008.1 XP_012746173.1 559 559 yes 480937 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 388259, 1230460 Natronorubrum sulfidifaciens, Natronorubrum sulfidifaciens JCM 14089 Archaea 495439728, 445588132 ELY42378.1 WP_008164423.1 L9W225 L9W225_9EURY 349 349 no 480938 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 478441, 1230456 Halorubrum kocurii, Halorubrum kocurii JCM 14978 Archaea 496124919, 445809832 EMA59868.1 WP_008849426.1 M0NQH1 M0NQH1_9EURY 361 379 no 480939 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 283909 Capitella teleta Invertebrates 443689232 ELT91679.1 407 458 yes 480940 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 222984, 1227494 Natrinema altunense, Natrinema altunense JCM 12890 Archaea 494168864, 445635363 ELY88533.1 WP_007108593.1 L9ZTP2 L9ZTP2_9EURY 349 349 no 480941 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2251, 1227459, 1227461 Haloferax gibbonsii ATCC 33959, Haloferax prahovense DSM 18310 Archaea 491118280, 445726101, 445718775 ELZ77718.1, ELZ70459.1 WP_004976731.1 M0H1P9, M0GHZ6 M0H1P9_9EURY, M0GHZ6_9EURY 343 344 no 480942 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 35742, 662476 Haloarcula sinaiiensis, Haloarcula sinaiiensis ATCC 33800 Archaea 491100584, 445762617 EMA13838.1 WP_004962184.1 M0JZA9 M0JZA9_9EURY 347 348 no 480943 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 368454, 1230455 Halorubrum arcis, Halorubrum arcis JCM 13916 Archaea 495269248, 445822084 EMA71858.1 WP_007994003.1 M0PPA8 M0PPA8_9EURY 345 347 no 480944 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 64713, 1227466 Halorubrum coriense, Halorubrum coriense DSM 10284 Archaea 493053894, 445695369 ELZ47476.1 WP_006113257.1 M0EI72 M0EI72_9EURY 345 347 no 480945 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 983506 Rhizoctonia solani AG1 IA Fungi UP000011668 443923490 ELU42722.1 473 497 yes 480946 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 44470, 1227497 Natronococcus amylolyticus, Natronococcus amylolyticus DSM 10524 Archaea 491708000, 445604459 ELY58407.1 WP_005555268.1 L9X9W1 L9X9W1_9EURY 348 349 no 480947 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2250, 931277 Halococcus morrhuae, Halococcus morrhuae DSM 1307 Archaea 490157043, 445789403 EMA40090.1 WP_004055715.1 M0M6U4 M0M6U4_HALMO 349 349 no 480948 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 88724, 1227496 Natrinema versiforme, Natrinema versiforme JCM 10478 Archaea 493475085, 445615669 ELY69310.1 WP_006430080.1 L9Y5G4 L9Y5G4_9EURY 349 349 no 480949 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 411361, 1227487 Halosarcina pallida, Halosarcina pallida JCM 14848 Archaea 495658977, 445682077 ELZ34501.1 WP_008383556.1 M0DGA6 M0DGA6_9EURY 343 344 no 480950 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29283, 1227468, 1227467 Halorubrum distributum, Halorubrum distributum JCM 10118, Halorubrum distributum JCM 9100 Archaea UP000011614 490735866, 445700820, 445695522 ELZ52811.1, ELZ47624.1 WP_004598195.1 M0EMJ0, M0EYC4 M0EMJ0_9EURY, M0EYC4_9EURY 345 347 no 480951 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 368623, 1230454 Halorubrum aidingense, Halorubrum aidingense JCM 13560 Archaea 495274085, 445818905 EMA68754.1 WP_007998840.1 M0PGN8 M0PGN8_9EURY 344 346 no 480952 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 129789, 1227491 Natrialba aegyptia, Natrialba aegyptia DSM 13077 Archaea 493714140, 445657605 ELZ10430.1 WP_006663717.1 M0BHU3 M0BHU3_9EURY 349 349 no 480953 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 332953, 1227490 Halovivax asiaticus, Halovivax asiaticus JCM 14624 Archaea 494970938, 445660752 ELZ13547.1 WP_007696964.1 M0BTX6 M0BTX6_9EURY 353 354 no 480954 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 914234 Gelatoporia subvermispora B Fungi UP000016930 449544766 EMD35738.1 507 507 yes 480955 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 504937, 1227488 Haloterrigena salina, Haloterrigena salina JCM 13891 Archaea 496170811, 445664011 ELZ16734.1 WP_008895318.1 M0C472 M0C472_9EURY 349 349 no 480956 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2248, 1227484 Halorubrum saccharovorum, Halorubrum saccharovorum DSM 1137 Archaea UP000053331 490151459, 445684281 ELZ36663.1 WP_004050142.1 M0DPA2 M0DPA2_9EURY 360 373 no 480957 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 68911, 1227492 Natrialba chahannaoensis, Natrialba chahannaoensis JCM 10990 Archaea 493159997, 445646107 ELY99099.1 WP_006167664.1 M0AKP1 M0AKP1_9EURY 353 353 no 480958 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 123783, 1227493 Natrialba hulunbeirensis, Natrialba hulunbeirensis JCM 10989 Archaea 493705259, 445633388 ELY86576.1 WP_006654963.1 L9ZKM1 L9ZKM1_9EURY 353 353 no 480959 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28442, 662477 Haloarcula vallismortis, Haloarcula vallismortis ATCC 29715 Archaea 490650194, 445759931 EMA11201.1 WP_004515188.1 M0JQC8 M0JQC8_HALVA 347 348 no 480960 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 64602, 29540 Natrialba asiatica, halophilic archaeon 172P1 Archaea 493047979, 445648321 ELZ01280.1 WP_006109127.1 M0ARV0 M0ARV0_NATA1 349 349 no 480961 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 255616, 662480 Haloferax sulfurifontis, Haloferax sulfurifontis ATCC BAA-897 Archaea 494484933, 445743915 ELZ95395.1 WP_007274406.1 M0IF45 M0IF45_9EURY 343 344 no 480962 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2251, 1227462, 1227463, 1227464, 1476858 Haloferax sp. ATCC BAA-644, Haloferax sp. ATCC BAA-645, Haloferax sp. ATCC BAA-646, Haloferax sp. Arc-Hr Archaea UP000011507, UP000011677 495849874, 445717282, 445713755, 445708916, 811260007 ELZ69000.1, ELZ65530.1, ELZ60751.1 WP_008574453.1 A0A0D6JPN8, M0G017, M0FL32, M0G9Z4 A0A0D6JPN8_9EURY, M0G017_9EURY, M0FL32_9EURY, M0G9Z4_9EURY 343 344 no 480963 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 36738, 1227456 Halococcus salifodinae, Halococcus salifodinae DSM 8989 Archaea 491183514, 445803353 EMA53650.1 WP_005041876.1 M0NAH0 M0NAH0_9EURY 348 349 no 480964 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 121872, 1227489 Haloterrigena thermotolerans, Haloterrigena thermotolerans DSM 11522 Archaea 493698911, 445662875 ELZ15638.1 WP_006648721.1 M0BZ02 M0BZ02_9EURY 349 349 no 480965 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 396317, 1227452 Haloarcula amylolytica, Haloarcula amylolytica JCM 13557 Archaea 495585098, 445772121 EMA23177.1 WP_008309677.1 M0KP78 M0KP78_9EURY 347 348 no 480966 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 56688, 1227483, 1227486 Halorubrum litoreum JCM 13561, Halorubrum terrestre JCM 10247 Archaea 494587678, 445812743, 445675254 EMA62731.1, ELZ27788.1 WP_007346274.1 M0CYR4, M0NY20 M0CYR4_9EURY, M0NY20_9EURY 345 347 no 480967 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 403191, 1230453 Haloferax elongans, Haloferax elongans ATCC BAA-1513 Archaea 495599846, 445733453 ELZ85022.1 WP_008324425.1 M0HMX8 M0HMX8_9EURY 343 344 no 480968 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 335952, 1227457 Halococcus thailandensis, Halococcus thailandensis JCM 13552 Archaea 495015841, 445800767 EMA51115.1 WP_007741852.1 M0N346 M0N346_9EURY 349 349 no 480969 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 69527, 1227495 Natrinema pallidum, Natrinema pallidum DSM 3751 Archaea 493191303, 445628971 ELY82268.1 WP_006184088.1 L9ZAT2 L9ZAT2_9EURY 349 349 no 480970 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 56688, 1227485 Halorubrum tebenquichense DSM 14210 Archaea 493678467, 445686948 ELZ39247.1 WP_006628691.1 M0DWY9 M0DWY9_9EURY 345 347 no 480971 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 413812, 1227498 Natronococcus jeotgali, Natronococcus jeotgali DSM 18795 Archaea 495701107, 445599844 ELY53867.1 WP_008425686.1 L9WWS2 L9WWS2_9EURY 348 349 no 480972 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 130048, 1227454 Halobiforma nitratireducens, Halobiforma nitratireducens JCM 10879 Archaea 493724765, 445779989 EMA30902.1 WP_006674139.1 M0LBG3 M0LBG3_9EURY 353 353 no 480973 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3659 Cucumis sativus Plants UP000029981 449468836, 700197866 KGN53024.1 XP_004152127.1 500 500 yes 480974 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 717646 Baudoinia compniacensis UAMH 10762 Fungi UP000011761 627799199, 449303725 EMC99732.1 XP_007672947.1 576 576 yes 480975 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 302484, 1227460 Haloferax larsenii, Haloferax larsenii JCM 13917 Archaea 494805030, 445729856 ELZ81450.1 WP_007540438.1 M0HAF1 M0HAF1_9EURY 343 344 no 480976 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 368624, 1227482 Halorubrum lipolyticum, Halorubrum lipolyticum DSM 21995 Archaea 495279438, 445812955 EMA62941.1 WP_008004192.1 M0NYN8 M0NYN8_9EURY 345 347 no 480977 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 403181, 662479 Haloferax mucosum, Haloferax mucosum ATCC BAA-1512 Archaea 495592627, 445747331 ELZ98787.1 WP_008317206.1 M0IRX1 M0IRX1_9EURY 329 329 no 480978 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 416585, 1227465 Halorubrum californiense, Halorubrum californiensis DSM 19288 Archaea 495721170, 445687783 ELZ40058.1 WP_008445749.1 M0DZ47 M0DZ47_9EURY 345 347 no 480979 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1151754 Pseudozyma antarctica T-34 Fungi UP000011976 443894210 670 670 yes 480980 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 35745, 662478 Haloferax denitrificans, Haloferax denitrificans ATCC 35960 Archaea 491112160, 445749786 EMA01228.1 WP_004970621.1 M0IYR9 M0IYR9_9EURY 343 344 no 480981 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 253107, 1227499 Natronolimnobius innermongolicus, Natronolimnobius innermongolicus JCM 12255 Archaea 494467893, 445608388 ELY62239.1 WP_007257393.1 L9XKD0 L9XKD0_9EURY 349 349 no 480982 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29282, 1227453 Haloarcula japonica, Haloarcula japonica DSM 6131 Archaea 490730708, 445778588 EMA29530.1 WP_004593082.1 M0LC59 M0LC59_HALJP 347 348 no 480983 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 63128, 1114856 Natronorubrum tibetense, Natronorubrum tibetense GA33 Archaea 493011988, 445584006 ELY38330.1 WP_006091424.1 L9VM91 L9VM91_9EURY 348 348 no 480984 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1227480, 1227481 Halorubrum hochstenium, Halorubrum hochstenium ATCC 700873 Archaea 495861354, 445701780 ELZ53753.1 WP_008585933.1 M0F320 M0F320_9EURY 345 347 no 480985 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 370323, 1230457 Haloterrigena limicola, Haloterrigena limicola JCM 13563 Archaea 495289618, 445664909 ELZ17595.1 WP_008014372.1 M0C325 M0C325_9EURY 348 349 no 480986 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 62319, 1227455 Halococcus saccharolyticus, Halococcus saccharolyticus DSM 5350 Archaea 492982322, 445794470 EMA45023.1 WP_006077896.1 M0MI72 M0MI72_9EURY 349 349 no 480987 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2252, 523841 Haloferax mediterranei, Haloferax mediterranei ATCC 33500 Archaea UP000011603 490158016, 445752968 EMA04387.1 WP_004056684.1 M0J5H3 M0J5H3_HALMT 329 329 no 480988 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 43776, 1230451 Haloarcula argentinensis, Haloarcula argentinensis DSM 12282 Archaea 491678751, 445773790 EMA24823.1 WP_005534893.1 M0KV76 M0KV76_HALAR 347 348 no 480989 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 160846, 1230458 Natrialba taiwanensis, Natrialba taiwanensis DSM 12281 Archaea 493881184, 445632276 ELY85488.1 WP_006827453.1 L9ZK03 L9ZK03_9EURY 349 349 no 480990 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 171164, 797114 Halosimplex carlsbadense, Halosimplex carlsbadense 2-9-1 Archaea 493939970, 445671825 ELZ24408.1 WP_006884169.1 M0CP37 M0CP37_9EURY 356 357 no 480991 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 283909 Capitella teleta Invertebrates 443685364 ELT88998.1 471 471 yes 480992 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 61858, 1227500 Natronorubrum bangense, Natronorubrum bangense JCM 10635 Archaea 492959475, 445589922 ELY44145.1 WP_006067560.1 L9W3W0 L9W3W0_9EURY 349 349 no 480993 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 246437 Tupaia chinensis Mammals UP000011518 562850126, 444721406 ELW62143.1 XP_006153825.1 490 490 yes 480994 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8932 Columba livia Vertebrates UP000053872 449266431 EMC77484.1 391 392 yes 608657 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 130081 Galdieria sulphuraria Plants UP000030680 545711339, 452824453 EME31456.1 XP_005707976.1 416 416 yes 608658 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4081 Solanum lycopersicum Plants UP000004994 UP000004994 460407878 XP_004249376.1 497 498 yes 608659 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1230383 Malassezia sympodialis ATCC 42132 Fungi UP000016925 465795169 609 3021 yes 608660 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 416273, 268739 Natronomonas moolapensis, Natronomonas moolapensis 8.8.11 Archaea UP000011867 505222512, 452207436, 452083536 WP_015409614.1, YP_007487558.1 M1XRK6 M1XRK6_NATM8 351 351 no 608661 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2209, 1236903 Methanosarcina mazei, Methanosarcina mazei Tuc01 Archaea UP000034872, UP000011718 505225049, 452210445, 814850759, 814786258, 814754110, 814748148, 452100347 KKH27400.1, KKG66221.1, KKG35593.1, KKG29952.1, AGF97287.1 WP_015412151.1, YP_007490559.1 A0A0F8G8Y4, M1P9W1 A0A0F8G8Y4_METMZ, M1P9W1_METMZ 330 333 no 608662 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3760 Prunus persica Plants UP000006882 595864772, 462407698 EMJ13032.1 XP_007211833.1 504 504 yes 608663 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9733 Orcinus orca Mammals 465988964 XP_004266367.1 489 489 yes 608664 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 665024, 701091 Cochliobolus heterostrophus ATCC 48331, Cochliobolus heterostrophus C5 Fungi UP000012338, UP000016936 477590024, 452000993 ENI07099.1, EMD93453.1 580 582 yes 608665 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 675120 Dothistroma septosporum NZE10 Fungi UP000016933 452846500 EME48432.1 575 575 yes 608666 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 692275 Mycosphaerella populorum SO2202 Fungi UP000016931 453088229 EMF16269.1 614 615 yes 608667 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 665912 Cochliobolus sativus ND90Pr Fungi UP000016934 628057993, 451854830 EMD68122.1 XP_007695450.1 M2THE2 M2THE2_COCSN 579 580 yes 608668 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8469 Chelonia mydas Vertebrates UP000031443 465975602 EMP34177.1 356 405 yes 608669 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 383855 Mycosphaerella fijiensis CIRAD86 Fungi UP000016932 631373878, 452988411 EME88166.1 XP_007921319.1 578 578 yes 723557 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9739 Tursiops truncatus Mammals 470606468 XP_004314208.1 503 503 yes 723558 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1291540, 1236689 Candidatus Methanomethylophilus alvus, Candidatus Methanomethylophilus alvus Mx1201 Archaea UP000012672 505317163, 477554476 AGI85116.1 WP_015504265.1 M9S9S4 M9S9S4_9EURY 325 326 no 723559 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1054217 Thermoplasmatales archaeon BRNA1 Archaea UP000012076 505304864, 472831712 AGI47449.1 WP_015491966.1 M4YK01 M4YK01_9EURY 325 326 no 723560 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1241935 Sulfolobus islandicus LAL14/1 Archaea UP000013006 478754571 AGJ63143.1 M9UAN2 M9UAN2_SULIS 300 304 no 723561 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1069680 Pneumocystis murina B123 Fungi UP000011958 667791903, 470316819 EMR08557.1 XP_007875089.1 410 425 yes 723562 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 667126, 1069083 Methanocaldococcus sp. KIN24-T80, Methanocaldococcus villosus KIN24-T80 Archaea UP000053695 490727529, 478432296 ENN96613.1 WP_004589942.1 N6V300 N6V300_9EURY 306 311 no 723563 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 77166 Dendroctonus ponderosae Invertebrates UP000030742 478251099 ENN71575.1 444 445 yes 723564 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1108050 Rhizoctonia solani AG-1 IB Fungi UP000012065 471905829 197 200 no 723565 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 73337 Ceratotherium simum simum Mammals 478535846 XP_004442047.1 489 489 yes 723566 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1229664 Fusarium oxysporum f. sp. cubense race 1 Fungi UP000016928 477511389 ENH63957.1 536 536 yes 723567 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4572 Triticum urartu Plants UP000015106 474374707 EMS64106.1 514 616 yes 723568 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1290391 Botryotinia fuckeliana BcDW1 Fungi UP000012045 472243774 EMR88413.1 564 564 yes 723569 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1213857 Colletotrichum orbiculare MAFF 240422 Fungi UP000014480 477533508 ENH85096.1 507 507 yes 723570 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1242690 Thermoplasmatales archaeon SCGC AB-539-C06 Archaea UP000053361 490692198, 478765519 ENO12436.1 WP_004556275.1 N6WLN9 N6WLN9_9EURY 336 338 no 723571 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1287681 Eutypa lata UCREL1 Fungi UP000012174 629674837, 471559636 EMR61966.1 XP_007798916.1 633 637 yes 723572 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1069680 Pneumocystis murina B123 Fungi UP000011958 667790338, 470317658 EMR09358.1 XP_007874308.1 461 462 yes 723573 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1069680 Pneumocystis murina B123 Fungi UP000011958 667790336, 470317659 EMR09359.1 XP_007874307.1 370 384 no 723574 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1242866 Thermoplasmatales archaeon SCGC AB-540-F20 Archaea 495880650, 471936194 EMR74487.1 WP_008605229.1 M7TCY6 M7TCY6_9EURY 336 339 no 723575 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 127582 Trichechus manatus latirostris Mammals 471362654 XP_004371886.1 489 489 yes 723576 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1130832, 5286 Rhodosporidium toruloides NP11, Rhodosporidium toruloides Fungi UP000016926 472581729, 647398307 EMS19452.1 568 568 yes 723577 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9708 Odobenus rosmarus divergens Mammals 472362214 XP_004400694.1 489 489 yes 723578 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 101020 Fragaria vesca subsp. vesca Plants 470148583 XP_004309836.1 487 487 yes 723579 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9708 Odobenus rosmarus divergens Mammals 472362216 XP_004400695.1 261 261 no 723580 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1089451, 1229665 Fusarium oxysporum f. sp. cubense tropical race 4 54006, Fusarium oxysporum f. sp. cubense race 4 Fungi UP000030685, UP000016929 591476505, 475675882 EXM07657.1, EMT72945.1 536 536 yes 1394338 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1299270 Wallemia ichthyophaga EXF-994 Fungi UP000014064 685951597, 505755197 EOQ99421.1 XP_009269647.1 588 589 yes 1394339 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7213 Ceratitis capitata Invertebrates 498995784, 577732557 JAB97916.1 XP_004533195.1 479 481 yes 1394340 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 467 469 yes 1394341 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9978 Ochotona princeps Mammals 504160850 XP_004591538.1 489 489 yes 1394342 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9978 Ochotona princeps Mammals 504160853 XP_004591539.1 261 261 no 1394343 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8839 Anas platyrhynchos Vertebrates UP000016666 483525207 EOB08895.1 374 374 no 1394344 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 280463 Emiliania huxleyi CCMP1516 Plants 551573305, 485623899 EOD20030.1 XP_005772459.1 591 639 no 1394345 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1168221 Coniosporium apollinis CBS 352.97 Fungi UP000016924 667840863, 494833259 EON69282.1 XP_007784599.1 572 572 yes 1394346 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 106582 Maylandia zebra Vertebrates 499037882, 499037880 XP_004569587.1, XP_004569586.1 494 494 yes 1394347 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 81985 Capsella rubella Plants UP000029121 565466224, 482559699 EOA23890.1 XP_006290992.1 488 488 yes 1394348 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 671987 Setosphaeria turcica Et28A Fungi UP000016935 636579137, 482815203 EOA91878.1 XP_008020907.1 596 596 yes 1394349 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9361 Dasypus novemcinctus Mammals 488514796 XP_004449411.1 489 489 yes 1394350 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 261 261 no 1394351 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7213 Ceratitis capitata Invertebrates 498945442, 577729343, 577729341 JAB96309.1, JAB96308.1 XP_004522211.1 454 465 yes 1394352 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1287680 Neofusicoccum parvum UCRNP2 Fungi UP000013521 615407114, 485925798 EOD50288.1 XP_007582232.1 393 695 no 1394353 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3827 Cicer arietinum Plants 502124464 XP_004498540.1 501 501 yes 1394354 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1305764 Pseudozyma hubeiensis SY62 Fungi UP000014071 808366088, 501305829 XP_012188531.1 664 665 yes 1394355 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1097556 Taphrina deformans PYCC 5710 Fungi UP000013776 501750254 499 499 yes 1394356 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 42254 Sorex araneus Mammals 505841656 XP_004614340.1 490 490 yes 1394357 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1316941, 387631 Archaeoglobus sulfaticallidus, Archaeoglobus sp. PM70-1 Archaea UP000013307 505403038, 484591898 AGK60541.1 WP_015590140.1 N0BJB2 N0BJB2_9EURY 321 325 no 1513314 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 999810 Botryotinia fuckeliana isolate T4 Fungi UP000008177 507414530 564 564 yes 1513315 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 85056 Trypanosoma cruzi marinkellei Invertebrates UP000007350 407404559 EKF29960.1 623 625 no 1513316 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1220926 Mucor circinelloides f. circinelloides 1006PhL Fungi UP000014254 511008784 EPB90043.1 432 434 yes 1513317 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10181 Heterocephalus glaber Rodents UP000006813 512990854, 861469353 XP_004857210.1, XP_012932344.1 435 459 yes 1513318 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 948595 Vavraia culicis 'floridensis' Fungi UP000011081 667633899, 429965333 ELA47330.1 XP_008074232.1 473 481 no 1513319 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 983506 Rhizoctonia solani AG1 IA Fungi UP000011668 443912879 ELU35988.1 200 210 no 1513320 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8090 Oryzias latipes Vertebrates UP000001038 432889886 XP_004075380.1 414 429 yes 1513321 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 32630 synthetic construct Synthetic 61372456 AAX43846.1 356 364 yes 1513322 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 246437 Tupaia chinensis Mammals UP000011518 444516399 ELV11148.1 455 626 yes 1513323 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 37682 Aegilops tauschii Plants 475508009 EMT05019.1 90 90 no 1513324 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1229909 Candidatus Nitrosopumilus sp. AR2 Archaea UP000006100 407047198 AFS81950.1 K0BAG3 K0BAG3_9ARCH 324 337 no 1513325 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7209 Loa loa Invertebrates UP000007040 393908161 EJD74933.1 353 355 no 1513326 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9595 Gorilla gorilla gorilla Primates UP000001519 426383440 XP_004058289.1 429 438 yes 1513327 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 13146 Melopsittacus undulatus Vertebrates 527265878 XP_005151130.1 398 472 yes 1513328 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 671987 Setosphaeria turcica Et28A Fungi UP000016935 636579733, 482814039 EOA90717.1 XP_008021205.1 183 191 no 1513329 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 320 330 no 1513330 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 339 354 no 1513331 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1290391 Botryotinia fuckeliana BcDW1 Fungi UP000012045 472242307 EMR87006.1 434 445 yes 1513332 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1120755 Plasmodium cynomolgi strain B Invertebrates UP000006319 457875610, 389585688 XP_004224365.1 683 683 no 1513333 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4555 Setaria italica Plants UP000004995 514719907 XP_004954353.1 466 473 yes 1513334 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5872, 1537102 Babesia equi, Babesia equi strain WA Invertebrates UP000031512 510900389, 429327496 AFZ79256.1 XP_004828922.1 440 443 yes 1513335 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4555 Setaria italica Plants UP000004995 514719911 XP_004954354.1 464 472 yes 1513336 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 692275 Mycosphaerella populorum SO2202 Fungi UP000016931 453089464 EMF17504.1 442 464 yes 1513337 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2173 Methanobrevibacter smithii Archaea 518095037 WP_019265245.1 332 334 no 1513338 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10036 Mesocricetus auratus Rodents 524968144 XP_005083958.1 489 489 yes 1513339 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 261 261 no 1513340 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 489138 Halarchaeum acidiphilum Archaea 519065812 WP_020221687.1 343 344 no 1513341 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 226 227 no 1513342 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 280699 Cyanidioschyzon merolae strain 10D Plants UP000007014 544218831, 449020121 XP_005539559.1 444 446 yes 1513343 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1268274 Blumeria graminis f. sp. tritici 96224 Fungi UP000053110 521781471 EPQ67742.1 438 441 yes 1513344 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1097556 Taphrina deformans PYCC 5710 Fungi UP000013776 501756133 514 622 yes 1513345 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1131266 Marine Group I thaumarchaeote SCGC AB-629-I23 Archaea 519092264 WP_020248139.1 324 331 no 1513346 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 59894 Ficedula albicollis Vertebrates UP000016665 525005047 XP_005050212.1 477 478 yes 1513347 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1294122 nanoarchaeote Nst1 Archaea UP000053279 490715387, 485654701 EOD42493.1 WP_004578036.1 R1E4F4 R1E4F4_9ARCH 88 89 no 1513348 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578456 Tremella mesenterica DSM 1558 Fungi UP000054539 589276288, 392576725 EIW69855.1 XP_007003874.1 518 532 no 1513349 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 305 399 no 1513350 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 371 373 yes 1513351 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 192259 Genlisea aurea Plants UP000015453 527206662 EPS72161.1 429 440 yes 1513352 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 566037 Eremothecium sp. FD-2008 Fungi UP000016920 513032456 AGO12448.1 566 583 yes 1513353 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 717944 Trametes versicolor FP-101664 SS1 Fungi UP000054317 636609287, 392568876 EIW62050.1 XP_008035778.1 551 552 no 1513354 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9601 Pongo abelii Primates UP000001595 297699595 XP_002826867.1 428 438 yes 1513355 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 743788 Fomitopsis pinicola FP-58527 SS1 Fungi UP000015241 527302924 EPT03704.1 529 535 no 1513356 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 187 448 no 1513357 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 302 354 no 1513358 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9544 Macaca mulatta Primates UP000006718 UP000006718 297271571 XP_002808156.1 436 452 yes 1513359 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 92 127 no 1513360 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1104572 516974873 WP_018193164.1 343 349 no 1513361 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 29760 Vitis vinifera Plants UP000009183 UP000009183 296085796 307 312 no 1513362 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 51337 Jaculus jaculus Rodents 507568422 XP_004667842.1 432 464 yes 1513363 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1262450 Ophiostoma piceae UAMH 11346 Fungi UP000016923 512188714 EPE04484.1 568 568 yes 1513364 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 597362 Agaricus bisporus var. burnettii JB137-S8 Fungi UP000008493 597977609, 409080129 EKM80490.1 XP_007328950.1 K5XYP0 K5XYP0_AGABU 505 507 no 1513365 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8932 Columba livia Vertebrates UP000053872 449265986 EMC77113.1 296 302 yes 1513366 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1080712 Methanomassiliicoccus luminyensis Archaea 518007107 WP_019177315.1 335 339 no 1513367 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9555 Papio anubis Primates UP000028761 685595016 XP_009187597.1 406 433 yes 1513368 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 983506 Rhizoctonia solani AG1 IA Fungi UP000011668 443926878 ELU45431.1 183 192 no 1513369 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6500 Aplysia californica Invertebrates 524903485 XP_005107942.1 438 442 yes 1513370 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6035 Encephalitozoon cuniculi Fungi 449329537 AGE95808.1 387 414 yes 1513371 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 224719 Methanobrevibacter sp. AbM4 Archaea UP000014066 511308659, 509085265 AGN17511.1 WP_016359208.1 R9SND2 R9SND2_9EURY 334 336 no 1513372 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1109443 Piriformospora indica DSM 11827 Fungi UP000007148 353241517 562 578 no 1513373 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 72004 Bos grunniens mutus Mammals 555952245, 440912315 ELR61899.1 XP_005888312.1 429 438 yes 1513374 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1028729 Fusarium pseudograminearum CS3096 Fungi UP000007978 685861521, 408394173 EKJ73407.1 XP_009257793.1 455 462 yes 1513375 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 72359 Trachipleistophora hominis Fungi UP000011185 440494529 ELQ76902.1 417 426 no 1513376 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1133968 Babesia microti strain RI Invertebrates UP000002899 829088055, 399219147 XP_012650442.1 414 427 yes 1513377 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3659 Cucumis sativus Plants UP000029981 778724226, 700188437 KGN43670.1 XP_011658762.1 459 462 yes 1513378 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1294122 nanoarchaeote Nst1 Archaea UP000053279 490715602, 485654613 EOD42406.1 WP_004578250.1 R1G2V8 R1G2V8_9ARCH 205 225 no 1513379 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 127582 Trichechus manatus latirostris Mammals 471372244 XP_004376210.1 429 438 yes 1513380 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1151754 Pseudozyma antarctica T-34 Fungi UP000011976 443898617 635 648 no 1513381 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 280463 Emiliania huxleyi CCMP1516 Plants 551604204, 485636571 EOD31158.1 XP_005783587.1 446 671 yes 1513382 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1076696 Entamoeba nuttalli P19 Invertebrates UP000006769 672799864, 407044581 EKE42693.1 XP_008854970.1 337 344 no 1513383 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 432 640 yes 1513384 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 42254 Sorex araneus Mammals 505788918 XP_004605318.1 429 439 yes 1513385 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9606 Homo sapiens Primates UP000005640 UP000005640 13160959 AAK13428.1 Q9BZG8 DPH1_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 431 443 yes 1513386 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 192259 Genlisea aurea Plants UP000015453 527206920 EPS72344.1 280 280 no 1513387 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 469 498 yes 1513388 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1120755 Plasmodium cynomolgi strain B Invertebrates UP000006319 457876010, 389585825 XP_004224502.1 452 456 no 1513389 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10160 Octodon degus Rodents 507660848 XP_004635394.1 422 438 yes 1513390 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 671144 Wallemia sebi CBS 633.66 Fungi UP000005242 588259253, 388580788 EIM21100.1 XP_006958780.1 488 495 yes 1513391 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6500 Aplysia californica Invertebrates 524898877 XP_005105882.1 502 503 yes 1513392 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1178016 Encephalitozoon romaleae SJ-2008 Fungi UP000010094 685880816, 396081729 AFN83344.1 XP_009264841.1 346 347 yes 1513393 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 869250 Theileria orientalis strain Shintoku Invertebrates UP000003786 697888506, 403221062 XP_009689496.1 492 764 yes 1513394 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9796, 9798 Equus caballus, Equus przewalskii Mammals UP000002281 UP000002281 338711111, 664734647 XP_001504395.3, XP_008524545.1 426 439 yes 1513395 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 338191 515506760 WP_016940014.1 323 331 no 1513396 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 665912 Cochliobolus sativus ND90Pr Fungi UP000016934 628070701, 451850825 EMD64126.1 XP_007700004.1 M2T4F7 M2T4F7_COCSN 463 475 yes 1513397 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 208 217 no 1513398 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9402 Pteropus alecto Mammals UP000010552 431891031 ELK01910.1 427 456 yes 1513399 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 130081 Galdieria sulphuraria Plants UP000030680 545709751, 452823656 EME30665.1 XP_005707185.1 459 460 yes 1513400 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1262903 Methanoculleus sp. CAG:1088 Archaea UP000018376 524837482 R7Q2Z7 R7Q2Z7_9EURY 325 326 no 1513401 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9669 Mustela putorius furo Mammals UP000000715 511844987 XP_004746906.1 422 436 yes 1513402 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 717646 Baudoinia compniacensis UAMH 10762 Fungi UP000011761 627808729, 449299073 EMC95087.1 XP_007677712.1 454 466 yes 1513403 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 721885 Stereum hirsutum FP-91666 SS1 Fungi UP000053927 597911583, 389747330 EIM88509.1 XP_007303090.1 529 530 no 1513404 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6087 Hydra vulgaris Invertebrates 449684115 XP_002161454.2 411 417 yes 1513405 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4572 Triticum urartu Plants UP000015106 474165925 EMS57392.1 212 214 no 1513406 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 32630 synthetic construct Synthetic 54696616, 61366153 AAV38680.1, AAX42821.1 356 364 yes 1513407 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9606, 32630 Homo sapiens, synthetic construct Primates, Synthetic UP000005640 UP000005640 54696618, 119610971, 61356316, 123981910, 123996743, 649148749 AAV38681.1, EAW90565.1, AAX41232.1, ABM82784.1, ABM85973.1, AIC61958.1 Q9BZG8 DPH1_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 356 363 yes 1513408 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 109478 Myotis brandtii Mammals UP000052978 554544177, 521026223 EPQ08011.1 XP_005866682.1 489 489 yes 1513409 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1287681 Eutypa lata UCREL1 Fungi UP000012174 629643976, 471573168 EMR71390.1 XP_007789518.1 423 428 yes 1513410 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 424 436 yes 1513411 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 154 172 no 1513412 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1194088 Halorubrum sp. T3 Archaea 515912415 WP_017342998.1 345 347 no 1513413 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 370355 Entamoeba invadens IP1 Invertebrates UP000014680 471188193, 440291230 ELP84499.1 XP_004183845.1 334 344 no 1513414 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1220926 Mucor circinelloides f. circinelloides 1006PhL Fungi UP000014254 511001317 EPB82801.1 554 562 yes 1513415 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1071383 Kazachstania naganishii CBS 8797 Fungi UP000006310 403217130 420 424 yes 1513416 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1279085 Fusarium fujikuroi IMI 58289 Fungi UP000016800 517313262 536 536 yes 1513417 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3641 Theobroma cacao Plants UP000026915 590683430, 508705533 EOX97429.1 XP_007041598.1 451 458 yes 1513418 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 106582 Maylandia zebra Vertebrates 499014401 XP_004558221.1 415 428 yes 1513419 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4555 Setaria italica Plants UP000004995 514798362 XP_004974122.1 510 512 yes 1513420 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 42068 Pneumocystis jirovecii Fungi 430811947 303 317 yes 1513421 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 764103 Mixia osmundae IAM 14324 Fungi UP000027399 658164703, 358056771 KEI39416.1 G7E3M4 G7E3M4_MIXOS 608 1543 no 1513422 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1263088 Methanobrevibacter smithii CAG:186 Archaea UP000018189 524835654 R7PV21 R7PV21_9EURY 327 329 no 1513423 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1130832, 5286 Rhodosporidium toruloides NP11, Rhodosporidium toruloides Fungi UP000016926 472587080, 647394734 EMS24579.1 590 594 no 1513424 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9371 Echinops telfairi Mammals 507663844, 850296229 XP_004706934.1, XP_012861301.1 342 363 yes 1513425 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5693 Trypanosoma cruzi Invertebrates UP000008313 407847772 EKG03377.1 618 620 no 1513426 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 665024, 701091 Cochliobolus heterostrophus ATCC 48331, Cochliobolus heterostrophus C5 Fungi UP000012338, UP000016936 477588227, 451996509 ENI05306.1, EMD88976.1 461 475 yes 1513427 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 475 489 yes 1513428 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10141 Cavia porcellus Rodents UP000005447 514460513 XP_003469582.2 424 438 yes 1513429 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 437163 Halomicrobium katesii Archaea 517069667 WP_018258485.1 347 348 no 1513430 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10090 Mus musculus Rodents UP000000589 UP000000589 148680849 EDL12796.1 278 293 no 1513431 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 383855 Mycosphaerella fijiensis CIRAD86 Fungi UP000016932 631370724, 452989802 EME89557.1 XP_007919742.1 458 468 yes 1513432 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 44056 Aureococcus anophagefferens Plants UP000002729 676381581, 323455863 EGB11731.1 XP_009034069.1 145 413 no 1513433 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 225400 Myotis davidii Mammals UP000010556 432096125 ELK26993.1 422 434 no 1513434 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 644352 Gaeumannomyces graminis var. tritici R3-111a-1 Fungi UP000006039 685417014, 402076542 EJT71965.1 XP_009227362.1 J3PCJ5 J3PCJ5_GAGT3 448 457 yes 1513435 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1245528 Candida maltosa Xu316 Fungi UP000011777 459373465 EMG50651.1 423 427 yes 1513436 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1295009 Methanomassiliicoccus sp. Mx1-Issoire Archaea UP000014070 509092634 AGN26652.1 R9T6T2 R9T6T2_9EURY 300 300 no 1513437 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1093141 Nannochloropsis gaditana CCMP526 Plants UP000009377 553187490, 387219721, 422294435 AFJ69569.1, EKU21735.1 XP_005854621.1 205 210 no 1513438 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1093141 Nannochloropsis gaditana CCMP526 Plants UP000009377 553187505, 422294440 EKU21740.1 XP_005854626.1 220 223 no 1513439 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 655819 Beauveria bassiana ARSEF 2860 Fungi UP000002762 667654019, 400597929 EJP65653.1 XP_008598841.1 458 463 yes 1513440 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1007084, 859192 Candidatus Nitrosoarchaeum limnia, marine archaeal group 1 strain BG20 Archaea 497875884, 509754682 EPA06479.1 WP_010190040.1 S2EW69 S2EW69_9ARCH 151 158 no 1513441 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 536 656 yes 1513442 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1007084, 859192 Candidatus Nitrosoarchaeum limnia, marine archaeal group 1 strain BG20 Archaea 497875892, 509754680 EPA06477.1 WP_010190048.1 S2EPW8 S2EPW8_9ARCH 151 158 no 1513443 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1041607 Wickerhamomyces ciferrii Fungi 754410797, 406604958 XP_011274535.1 417 423 yes 1513444 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1245528 Candida maltosa Xu316 Fungi UP000011777 459368949 EMG47509.1 126 126 no 1513445 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1124627 Dekkera bruxellensis AWRI1499 Fungi UP000004997 385303495 EIF47564.1 302 305 yes 1513446 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8839 Anas platyrhynchos Vertebrates UP000016666 514704329 XP_005009295.1 371 372 no 1513447 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1277687 Pseudozyma flocculosa PF-1 Fungi UP000053664 630964704, 521585621 EPQ29298.1 XP_007878760.1 679 679 yes 1513448 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5127, 1279085 Gibberella fujikuroi, Fusarium fujikuroi IMI 58289 Fungi UP000036542, UP000016800 829102408, 829128044, 829142154, 517311448 KLO79307.1, KLP02942.1, KLP13988.1 451 456 yes 1513449 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 143302 Condylura cristata Mammals 507935710 XP_004678962.1 487 487 yes 1513450 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1262450 Ophiostoma piceae UAMH 11346 Fungi UP000016923 512193510 EPE09267.1 534 545 yes 1513451 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 41875 Bathycoccus prasinos Plants 612398039, 412986353 XP_007514539.1 454 457 yes 1513452 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 73337 Ceratotherium simum simum Mammals 478518260 XP_004433359.1 430 438 yes 1513453 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 764 764 yes 1513454 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 441 442 yes 1513455 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1299270 Wallemia ichthyophaga EXF-994 Fungi UP000014064 685940986, 505760782 EOR04847.1 XP_009265868.1 524 526 yes 1513456 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 261 261 no 1513457 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 670483 Gloeophyllum trabeum ATCC 11539 Fungi UP000030669 630358519, 521722900 EPQ53261.1 XP_007868534.1 516 516 no 1513458 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1116229 Glarea lozoyensis ATCC 20868 Fungi UP000016922 636764545, 512199705 EPE28538.1 XP_008084446.1 434 445 yes 1513459 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 335 336 no 1513460 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9606 Homo sapiens Primates UP000005640 UP000005640 1438781, 1490415 AAB36297.1, AAD10198.1 Q9BZG8 DPH1_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} fig|233412.1.peg.359 356 363 yes 1513461 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 189 211 no 1513462 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1333698, 1355161 Zygosaccharomyces bailii CLIB 213, Zygosaccharomyces bailii ISA1307 Fungi UP000019375, UP000032161 523424839, 578047534 424 424 yes 1513463 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9606 Homo sapiens Primates UP000005640 UP000005640 1438796, 5955882, 6004791 AAB36421.1, AAE07538.1, AAE23218.1 435 443 yes 1513464 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 741275 Punctularia strigosozonata HHB-11173 SS5 Fungi UP000054196 599103075, 390600888 EIN10282.1 XP_007381794.1 567 572 no 1513465 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1186058, 1220162 Trichosporon asahii var. asahii CBS 2479, Trichosporon asahii var. asahii CBS 8904 Fungi UP000002748, UP000006757 401882195, 406701379 EJT46464.1, EKD04526.1 511 519 no 1513466 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 675120 Dothistroma septosporum NZE10 Fungi UP000016933 452846680 EME48612.1 452 464 yes 1513467 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 936046 Agaricus bisporus var. bisporus H97 Fungi UP000010818 568452318, 426198105 EKV48031.1 XP_006459896.1 506 508 no 1513468 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1213857 Colletotrichum orbiculare MAFF 240422 Fungi UP000014480 477527132 ENH78973.1 442 447 yes 1513469 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 226230 Saccharomyces kudriavzevii IFO 1802 Fungi UP000002753 401839199 EJT42515.1 425 428 yes 1513470 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1257118 Acanthamoeba castellanii str. Neff Invertebrates UP000011083 470426729, 440794762 ELR15917.1 XP_004337930.1 411 411 no 1513471 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1333523 Salinarchaeum sp. Harcht-Bsk1 Archaea UP000014072 521282773, 507916549 AGN02147.1 WP_020447041.1 R4W670 R4W670_9EURY 359 359 no 1513472 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 885315, 885311 Entamoeba histolytica HM-3:IMSS, Entamoeba histolytica KU27 Invertebrates UP000030780, UP000011755 472463230, 449703021 EMS16254.1, EMD43541.1 337 344 no 1513473 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8469 Chelonia mydas Vertebrates UP000031443 465988727 EMP37823.1 402 677 yes 1513474 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 303 319 no 1513475 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3760 Prunus persica Plants UP000006882 596130352, 462419084 EMJ23347.1 XP_007222148.1 443 446 yes 1513476 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9739 Tursiops truncatus Mammals 470631568 XP_004321992.1 424 438 yes 1513477 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8128 Oreochromis niloticus Vertebrates UP000005207 348505236 XP_003440167.1 415 428 yes 1513478 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 881290, 935791 Nematocida parisii ERTm1, Nematocida parisii ERTm3 Fungi UP000002871, UP000002872 906370878, 387597023, 387593366 EIJ94643.1, EIJ88390.1 XP_013057999.1 355 362 yes 1513479 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1358809 Spraguea lophii 42_110 Fungi UP000014978 523781278 EPR80131.1 338 344 yes 1513480 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 993615 Vittaforma corneae ATCC 50505 Fungi UP000011082 667640191, 429962404 ELA41948.1 XP_007604412.1 353 358 yes 1513481 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 235443 Cryptococcus neoformans var. grubii H99 Fungi UP000010091 799315854, 405118117 AFR92892.1 XP_012046945.1 521 529 no 1513482 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 933388 Penicillium decumbens 114-2 Fungi UP000019376 525584242 EPS30492.1 569 570 yes 1513483 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9371 Echinops telfairi Mammals 507632818 XP_004699548.1 489 489 yes 1513484 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 41875 Bathycoccus prasinos Plants 612392589, 412988600 XP_007511815.1 257 292 no 1513485 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 15368 Brachypodium distachyon Plants UP000008810 UP000008810 357137598 XP_003570387.1 466 469 yes 1513486 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 508771 Toxoplasma gondii ME49 Invertebrates UP000001529 527307969 EPT24608.1 1283 1283 no 1513487 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 101020 Fragaria vesca subsp. vesca Plants 470101190, 764504876 XP_004287061.1, XP_011460533.1 441 443 yes 1513488 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 907965 Encephalitozoon hellem ATCC 50504 Fungi UP000010086 401827021, 392998609 AFM98622.1 XP_003887603.1 345 347 yes 1513489 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1355160, 284813 Encephalitozoon cuniculi EcunIII-L, Encephalitozoon cuniculi GB-M1 Fungi UP000037166, UP000000819 887495069, 510120825, 392512759 KMV65822.1 Q8SUZ5 DPH1_ENCCU 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 345 347 yes 1513490 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2769 Chondrus crispus Plants 546303974, 507108573 XP_005712185.1 410 426 yes 1513491 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 409 425 yes 1513492 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 670483 Gloeophyllum trabeum ATCC 11539 Fungi UP000030669 630345147, 521729299 EPQ59384.1 XP_007861874.1 456 459 no 1513493 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2186 Methanothermococcus thermolithotrophicus Archaea 516898068 WP_018154365.1 309 312 no 1513494 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1294121 516994327 WP_018204069.1 197 205 no 1513495 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1229665, 1089451 Fusarium oxysporum f. sp. cubense race 4, Fusarium oxysporum f. sp. cubense tropical race 4 54006 Fungi UP000016929, UP000030685 475663651, 591481055 EMT61446.1, EXM12115.1 445 453 yes 1513496 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1126212 Macrophomina phaseolina MS6 Fungi UP000007129 407917863 EKG11165.1 483 499 no 1513497 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 37682 Aegilops tauschii Plants 475508008 EMT05018.1 357 363 no 1513498 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1333698, 1355161 Zygosaccharomyces bailii CLIB 213, Zygosaccharomyces bailii ISA1307 Fungi UP000019375, UP000032161 523425065, 578047358 528 537 yes 1513499 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 464 893 yes 1513500 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6293 Wuchereria bancrofti Invertebrates UP000004810 402580785 EJW74734.1 212 212 no 1513501 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1286976 Togninia minima UCRPA7 Fungi UP000014074 631241894, 500256066 EON99384.1 XP_007915869.1 318 354 no 1513502 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 344 359 yes 1513503 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1133968 Babesia microti strain RI Invertebrates UP000002899 829085755, 908661106 XP_012649292.1 431 431 yes 1513504 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1305764 Pseudozyma hubeiensis SY62 Fungi UP000014071 808372293, 501308759 XP_012191240.1 607 608 no 1513505 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1104572 519109976 WP_020265851.1 343 347 no 1513506 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 743788 Fomitopsis pinicola FP-58527 SS1 Fungi UP000015241 527293803 EPS94679.1 498 498 yes 1513507 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 566037 Eremothecium sp. FD-2008 Fungi UP000016920 513031548 AGO11557.1 425 427 yes 1513508 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 443 472 no 1513509 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1268274 Blumeria graminis f. sp. tritici 96224 Fungi UP000053110 521774494 EPQ65671.1 369 369 no 1513510 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 127 141 no 1513511 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 81985 Capsella rubella Plants UP000029121 565432891, 482549155 EOA13349.1 XP_006280451.1 445 453 yes 1513512 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 42068 Pneumocystis jirovecii Fungi 430812595 222 222 no 1513513 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 42068 Pneumocystis jirovecii Fungi 430812596 232 232 no 1513514 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 86 86 no 1513515 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9606 Homo sapiens Primates UP000005640 UP000005640 211826117 AAH03099.2 Q9BZG8 DPH1_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 416 436 yes 1513516 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 80884, 759273 Colletotrichum higginsianum, Colletotrichum higginsianum IMI 349063 Fungi UP000007174 380485064 H1VH99 H1VH99_COLHI 443 449 yes 1513517 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 869250 Theileria orientalis strain Shintoku Invertebrates UP000003786 697890305, 403221961 XP_009690394.1 426 435 yes 1513518 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 741705 Coniophora puteana RWD-64-598 SS2 Fungi UP000053558 628851115, 392586829 EIW76164.1 XP_007773430.1 538 541 no 1513519 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 10090 Mus musculus Rodents UP000000589 UP000000589 148698586 EDL30533.1 244 261 no 1513520 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 866790 Methanothermobacter thermautotrophicus CaT2 Archaea UP000031654 851312707, 427189726 WP_048175850.1 T2GK75 T2GK75_9EURY 328 330 no 1513521 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3641 Theobroma cacao Plants UP000026915 590664975, 508773857 EOY21113.1 XP_007036612.1 501 833 yes 1513522 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 452 471 yes 1513523 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 732165 Dichomitus squalens LYAD-421 SS1 Fungi UP000053319 597991049, 395328763 EJF61153.1 XP_007365982.1 561 564 no 1513524 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 31033 Takifugu rubripes Vertebrates UP000005226 UP000005226 410910182, 768932334, 768932336 XP_003968569.1, XP_011606822.1, XP_011606823.1 415 426 yes 1513525 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 717982 Auricularia delicata TFB-10046 SS5 Fungi UP000006514 598014765, 393246187 EJD53696.1 XP_007338035.1 491 497 no 1513526 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 39432 Saimiri boliviensis boliviensis Primates 725580455 XP_010341973.1 356 363 yes 1513527 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 345 352 no 1513528 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 59894 Ficedula albicollis Vertebrates UP000016665 525018645 XP_005056862.1 434 502 yes 1513529 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1111077 Claviceps purpurea 20.1 Fungi UP000016801 399169046 446 459 yes 1513530 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 109478 Myotis brandtii Mammals UP000052978 521020953 EPQ02741.1 407 425 yes 1513531 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 392 458 yes 1513532 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1116229 Glarea lozoyensis ATCC 20868 Fungi UP000016922 636768063, 512198180 EPE27015.1 XP_008086205.1 569 569 yes 1513533 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1213859 Colletotrichum gloeosporioides Nara gc5 Fungi UP000011096 596654266, 429862461 ELA37109.1 XP_007273806.1 419 428 yes 1513534 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1230383 Malassezia sympodialis ATCC 42132 Fungi UP000016925 465794625 507 523 yes 1513535 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 407 413 yes 1513536 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1277687 Pseudozyma flocculosa PF-1 Fungi UP000053664 630971610, 521582157 EPQ26028.1 XP_007882213.1 619 628 no 1513537 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578461 Nosema bombycis CQ1 Fungi UP000016927 484857426 EOB15168.1 367 373 no 1513538 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 37682 Aegilops tauschii Plants 475528789 EMT07681.1 385 390 yes 1513539 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9606 Homo sapiens Primates UP000005640 UP000005640 119610972 EAW90566.1 425 432 no 1513540 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9733 Orcinus orca Mammals 465993323 XP_004267102.1 422 438 yes 1513541 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10090 Mus musculus Rodents UP000000589 UP000000589 20268670 AAM14629.1 Q5NCQ5 DPH1_MOUSE 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} fig|10090.3.peg.24711 424 438 yes 1513542 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1003232 Edhazardia aedis USNM 41457 Fungi UP000003163 402468496 EJW03648.1 426 431 yes 1513543 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5872, 1537102 Babesia equi, Babesia equi strain WA Invertebrates UP000031512 510910108, 428672827 EKX73740.1 XP_004833192.1 449 449 yes 1513544 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1168221 Coniosporium apollinis CBS 352.97 Fungi UP000016924 667838273, 494831557 EON67988.1 XP_007783305.1 445 461 yes 1513545 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3847, 3848 Glycine max, Glycine soja Plants UP000008827 UP000008827, UP000053555 356529829, 734348172 KHN11750.1 XP_003533490.1 460 467 yes 1513546 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1093141 Nannochloropsis gaditana CCMP526 Plants UP000009377 553182991, 422295240 EKU22539.1 XP_005853821.1 240 244 no 1513547 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 933388 Penicillium decumbens 114-2 Fungi UP000019376 525582042 EPS28292.1 428 431 yes 1513548 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1172189 Oxytricha trifallax Invertebrates UP000006077 403367655 EJY83650.1 428 614 yes 1513549 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 51337 Jaculus jaculus Rodents 507578096 XP_004672570.1 489 489 yes 1513550 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 350 363 yes 1513551 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10160 Octodon degus Rodents 507713271 XP_004647681.1 490 490 yes 1513552 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 433 484 yes 1513553 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4577 Zea mays Plants UP000007305 670404269, 413939463 AFW74014.1 XP_008643787.1 480 483 yes 1513554 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 599839 Fibroporia radiculosa Fungi UP000006352 807747867, 403412745 XP_012178728.1 525 529 no 1513555 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1284197 Dactylellina haptotyla CBS 200.50 Fungi UP000015100 748492990, 526202636 EPS42969.1 XP_011109079.1 536 536 yes 1513556 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1143193, 1143189 Magnaporthe oryzae P131, Magnaporthe oryzae Y34 Fungi UP000011085, UP000011086 440479333, 440465168 ELQ60105.1, ELQ34508.1 452 463 yes 1513557 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 280699 Cyanidioschyzon merolae strain 10D Plants UP000007014 544213830, 449017624 XP_005537062.1 317 383 no 1513558 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 400 435 yes 1513559 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9361 Dasypus novemcinctus Mammals 488597284 XP_004483807.1 415 428 yes 1513560 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 317 329 yes 1513561 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 516 516 yes 1513562 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9669 Mustela putorius furo Mammals UP000000715 511831870 XP_004740602.1 489 489 yes 1513563 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 440 440 yes 1513564 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 261 261 no 1513565 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1245528 Candida maltosa Xu316 Fungi UP000011777 459370347 EMG48469.1 126 126 no 1513566 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294123 Sulfolobales archaeon Acd1 Archaea 519042931 WP_020198806.1 331 332 no 1513567 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4081 Solanum lycopersicum Plants UP000004994 UP000004994 460392311, 723709409, 723709412 XP_004241760.1, XP_010322707.1, XP_010322708.1 474 483 yes 1513568 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 578461 Nosema bombycis CQ1 Fungi UP000016927 484851622 EOB11153.1 363 369 no 1513569 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 881290, 935791 Nematocida parisii ERTm1, Nematocida parisii ERTm3 Fungi UP000002871, UP000002872 906373749, 387595638, 387594165 EIJ93261.1, EIJ89189.1 XP_013059431.1 420 428 no 1513570 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 120017 Ustilago hordei Fungi 388853692 592 594 no 1513571 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3827 Cicer arietinum Plants 502159294 XP_004511457.1 461 465 yes 1513572 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 745407 Dacryopinax sp. DJM-731 SS1 Fungi UP000030653 402225087 EJU05148.1 518 519 no 1513573 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 456 459 yes 1513574 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 694068 Fomitiporia mediterranea MF3/22 Fungi UP000053630 595780332, 393215941 EJD01432.1 XP_007268709.1 513 517 no 1513575 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 77166 Dendroctonus ponderosae Invertebrates UP000030742 478250952, 546682679 ENN71436.1, ERL92591.1 402 404 yes 1513576 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 507601 Toxoplasma gondii GT1 Invertebrates UP000005641 523577295 EPR63940.1 1283 1283 no 1513577 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9606 Homo sapiens Primates UP000005640 UP000005640 64654638 AAH96088.1 Q9BZG8 DPH1_HUMAN 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305} 295 303 no 1513578 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1284197 Dactylellina haptotyla CBS 200.50 Fungi UP000015100 748482487, 526204885 EPS45059.1 XP_011106976.1 437 445 yes 1513579 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 348 699 yes 1513580 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1195612 Chroomonas mesostigmatica CCMP1168 Plants 399949790 AFP65447.1 410 423 yes 1513581 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 261 261 no 1513582 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 159749 Thalassiosira oceanica Plants UP000007974 397576181 EJK50109.1 496 581 no 1513583 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 436 442 yes 1643177 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7955 Danio rerio Vertebrates UP000000437 UP000000437 528501761 XP_005157638.1 427 439 yes 1643178 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7955 Danio rerio Vertebrates UP000000437 UP000000437 528501763 XP_005157639.1 426 438 yes 1643179 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 59799 Crithidia deanei Invertebrates UP000015341 528257028 EPY36963.1 298 300 yes 1643180 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 28005 Blastocrithidia culicis Invertebrates UP000015354 528232458 EPY26954.1 316 319 no 1643181 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 59799 Crithidia deanei Invertebrates UP000015341 528230667 EPY26316.1 376 381 yes 1643182 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 456 549 yes 1643183 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 445 538 yes 1643184 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 59799 Crithidia deanei Invertebrates UP000015341 528242457 EPY31185.1 613 668 no 1643185 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 431 453 yes 1643186 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 911162 Ophiocordyceps sinensis CO18 Fungi UP000019374 531856928 EQK97892.1 172 182 no 1643187 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 419612 Camelus ferus Mammals UP000030684 530667184 EQB77485.1 445 650 yes 1643188 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 911162 Ophiocordyceps sinensis CO18 Fungi UP000019374 531856930 EQK97894.1 303 353 no 1643189 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 261388 Ferroplasma sp. Type II Archaea UP000018013 546142466, 530563620 EQB74516.1 WP_021786042.1 T0NGL5 T0NGL5_9EURY 323 334 no 1643190 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1365176 Thermofilum sp. 1910b Archaea UP000015543 530454703 AGT35506.1 S5ZLJ7 S5ZLJ7_9CREN 331 340 no 1643191 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1037528 Nosema apis BRL 01 Fungi UP000053780 530541868 EQB61046.1 406 417 yes 1643192 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 653667 Schizosaccharomyces cryophilus NRRL Y-48691 Fungi UP000015464 528316087 EPY50665.1 499 508 yes 1643193 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 483514 Schizosaccharomyces octosporus yFS286 Fungi UP000016088 528062775 EPX72338.1 498 507 yes 1643194 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28005 Blastocrithidia culicis Invertebrates UP000015354 528244286 EPY32051.1 343 344 yes 1643195 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 447095 Ajellomyces dermatitidis ATCC 26199 Fungi UP000053869 531984439 EQL35026.1 598 598 yes 1643196 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 59799 Crithidia deanei Invertebrates UP000015341 528261346 EPY38504.1 352 354 yes 1643197 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1033806 Halorhabdus tiamatea SARL4B Archaea UP000015381 528527523 S6CVX0 S6CVX0_9EURY 362 365 no 1643198 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1237896 Colletotrichum gloeosporioides Cg-14 Fungi UP000015530 530468946 EQB50199.1 510 510 yes 1643199 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 667135 Thermoplasmatales archaeon A-plasma Archaea UP000018337 546153330, 530559318 EQB70509.1 WP_021795602.1 T0M182 T0M182_9EURY 326 333 no 1643200 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 447095 Ajellomyces dermatitidis ATCC 26199 Fungi UP000053869 531987556 EQL38143.1 437 445 yes 1643201 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 483514 Schizosaccharomyces octosporus yFS286 Fungi UP000016088 528062057 EPX71621.1 434 435 yes 1643202 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 546991 Blumeria graminis f. sp. hordei DH14 Fungi UP000015441 528302186 688 689 yes 1643203 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 988480 Rozella allomycis CSF55 Fungi UP000030755 528896107 EPZ36058.1 390 392 yes 1643204 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 261391 Thermoplasmatales archaeon Gpl Archaea UP000018202 546147359, 530557555 EQB68845.1 WP_021789729.1 T0N5A9 T0N5A9_9EURY 325 333 no 1643205 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 667137 Thermoplasmatales archaeon E-plasma Archaea UP000018052 546150550, 530555198 EQB66585.1 WP_021792891.1 T0MYV2 T0MYV2_9EURY 327 335 no 1643206 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 59799 Crithidia deanei Invertebrates UP000015341 528259057, 528242557 EPY37749.1, EPY31225.1 377 381 yes 1643207 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 79684 Microtus ochrogaster Rodents 532011652 XP_005349616.1 415 436 yes 1643208 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 546991 Blumeria graminis f. sp. hordei DH14 Fungi UP000015441 528301475 442 444 yes 1643209 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1156394 Saprolegnia diclina VS20 Plants UP000030762 669141124, 530742183 EQC40425.1 XP_008606124.1 425 426 yes 1643210 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 28005 Blastocrithidia culicis Invertebrates UP000015354 528240297 EPY30251.1 306 308 no 1643211 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 261 261 no 1643212 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 988480 Rozella allomycis CSF55 Fungi UP000030755 528893872 EPZ34132.1 226 311 no 1643213 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 667138 Thermoplasmatales archaeon I-plasma Archaea UP000017931 546148661, 530553971 EQB65369.1 WP_021791013.1 T0LL93 T0LL93_9EURY 328 332 no 1643214 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8954 Falco peregrinus Vertebrates 529441719 XP_005240591.1 417 579 yes 1643215 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8478 Chrysemys picta bellii Vertebrates 530617305 XP_005298388.1 333 333 no 1643216 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 28005 Blastocrithidia culicis Invertebrates UP000015354 528216282 EPY19853.1 147 148 no 1643217 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8478 Chrysemys picta bellii Vertebrates 530640866 XP_005307190.1 405 405 yes 1643218 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 653667 Schizosaccharomyces cryophilus NRRL Y-48691 Fungi UP000015464 528315875 EPY50454.1 433 433 yes 1643219 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 419612 Camelus ferus Mammals UP000030684 530668008 EQB78309.1 493 541 no 1643220 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1156394 Saprolegnia diclina VS20 Plants UP000030762 669152350, 530736623 EQC34865.1 XP_008611737.1 494 499 yes 1643221 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1071085 haloarchaeon 3A1_DGR Archaea 544639167 WP_021073729.1 343 347 no 1643222 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1237896 Colletotrichum gloeosporioides Cg-14 Fungi UP000015530 530466643 EQB48416.1 446 453 yes 1643223 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 43179 Spermophilus tridecemlineatus Rodents UP000005215 532064244 XP_005317989.1 489 489 yes 1643224 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 43179 Spermophilus tridecemlineatus Rodents UP000005215 532084469 XP_005327965.1 419 436 yes 1643225 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 43179 Spermophilus tridecemlineatus Rodents UP000005215 532064246 XP_005317990.1 261 261 no 1643226 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8954 Falco peregrinus Vertebrates 529437431 XP_005238478.1 409 410 yes 1643227 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 988480 Rozella allomycis CSF55 Fungi UP000030755 528896248 EPZ36160.1 213 214 no 1643228 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 79684 Microtus ochrogaster Rodents 532054777 XP_005370107.1 489 489 yes 1643229 uncharacterized Radical SAM 3-amino-3-carboxypropyl radical forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 79684 Microtus ochrogaster Rodents 532054779 XP_005370108.1 261 261 no 1698294 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 345164 Falco cherrug Vertebrates 541972993 XP_005439966.1 437 504 yes 1698295 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 34839 Chinchilla lanigera Rodents 533196118 XP_005410750.1 261 261 no 1698296 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1085028 halophilic archaeon J07HX64 Archaea 544603801, 541200923 ERH08988.1 WP_021042256.1 U1QPF6 U1QPF6_9EURY 409 810 no 1698297 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10029 Cricetulus griseus Rodents UP000030759 537141403 ERE67973.1 374 600 yes 1698298 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1238426 Haloquadratum sp. J07HQX50 Archaea 544620572, 541189635 ERG98023.1 WP_021058908.1 U1NLW5 U1NLW5_9EURY 343 344 no 1698299 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 869896, 1070774, 1238427 Halonotius sp. J07HN4, Halonotius sp. J07HN6 Archaea 544600864, 541197289, 541193665 ERH05452.1, ERH02013.1 WP_021039342.1 U1Q6B2, U1QJ39 U1Q6B2_9EURY, U1QJ39_9EURY 346 347 no 1698300 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 48883 Geospiza fortis Vertebrates 543273122 XP_005425534.1 346 349 yes 1698301 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8932 Columba livia Vertebrates UP000053872 543719972 XP_005501198.1 396 425 yes 1698302 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1238428 Halorubrum sp. J07HR59 Archaea UP000054356 541195768 ERH04025.1 U1NKC1 U1NKC1_9EURY 224 224 no 1698303 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1263415 Endocarpon pusillum Z07020 Fungi UP000019373 629636568, 539440294 ERF75772.1 XP_007786930.1 436 445 yes 1698304 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10029 Cricetulus griseus Rodents UP000030759 537141404 ERE67974.1 392 435 yes 1698305 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6253 Ascaris suum Invertebrates UP000017900 541039516 ERG79271.1 476 477 yes 1698306 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1085029 halophilic archaeon J07HB67 Archaea 541203328 ERH11308.1 U1QVE6 U1QVE6_9EURY 351 351 no 1698307 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 44394 Zonotrichia albicollis Vertebrates 542146740 XP_005482382.1 439 476 yes 1698308 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 181119 Pseudopodoces humilis Vertebrates 543365300 XP_005526011.1 410 552 yes 1698309 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 181119 Pseudopodoces humilis Vertebrates 543352768 XP_005521136.1 477 478 yes 1698310 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 44394 Zonotrichia albicollis Vertebrates 542171330 XP_005493740.1 342 400 yes 1698311 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1070774 Halonotius sp. J07HN4 Archaea 544601163, 541197588 ERH05751.1 WP_021039641.1 U1P630 U1P630_9EURY 351 352 no 1698312 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 48883 Geospiza fortis Vertebrates 543266372 XP_005423217.1 430 431 yes 1698313 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 345164 Falco cherrug Vertebrates 541964869 XP_005437466.1 404 405 yes 1698314 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 489138, 1261545 Halarchaeum acidiphilum, Halarchaeum acidiphilum MH1-52-1 Archaea 545903305, 543416262 WP_021780346.1 U2YW12 U2YW12_9EURY 353 405 no 1698315 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9541 Macaca fascicularis Primates UP000009130 544496203 XP_005582524.1 421 438 yes 1698316 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 34839 Chinchilla lanigera Rodents 533178830 XP_005402655.1 422 438 yes 1698317 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 34839 Chinchilla lanigera Rodents 533196114 XP_005410748.1 489 489 yes 1698318 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 34839 Chinchilla lanigera Rodents 533196116 XP_005410749.1 425 434 yes 1698319 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1325472 halophilic archaeon J07HX5 Archaea UP000053694 541180241 ERG88838.1 U1MXV3 U1MXV3_9EURY 348 350 no 1698320 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1263415 Endocarpon pusillum Z07020 Fungi UP000019373 629652871, 539435241 ERF71644.1 XP_007802853.1 562 563 yes 1698321 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8932 Columba livia Vertebrates UP000053872 543721971 XP_005502175.1 373 374 yes 1698322 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 293091, 1238425 Haloquadratum walsbyi, Haloquadratum walsbyi J07HQW2 Archaea 544615924, 541186359 ERG94783.1 WP_021054274.1 U1NDH4 U1NDH4_9EURY 343 344 no 1698323 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9541 Macaca fascicularis Primates UP000009130 544406526 XP_005543691.1 261 261 no 1698324 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10029 Cricetulus griseus Rodents UP000030759 537141402 ERE67972.1 362 614 yes 1698325 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9541 Macaca fascicularis Primates UP000009130 544406524 XP_005543690.1 489 489 yes 1698326 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 293091, 1238424 Haloquadratum walsbyi, Haloquadratum walsbyi J07HQW1 Archaea 544613631, 541183962 ERG92472.1 WP_021051982.1 U1PFS5 U1PFS5_9EURY 344 344 no 1747949 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13333 Amborella trichopoda Plants UP000017836 548862996 ERN20352.1 312 318 no 1747950 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9823 Sus scrofa Mammals UP000008227 UP000008227 545859606 XP_003131871.3 425 439 yes 1747951 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1397361, 1391915 Sporothrix schenckii 1099-18, Sporothrix schenckii ATCC 58251 Fungi UP000033710, UP000018087 780593435, 550811543 KJR84094.1, ERT03455.1 A0A0F2M4S9 A0A0F2M4S9_SPOSC 519 524 yes 1747952 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1076935 Pyronema omphalodes CBS100304 Fungi UP000018144 549046561 421 422 yes 1747953 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 303518 Pundamilia nyererei Vertebrates 548404643 XP_005739424.1 415 428 yes 1747954 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9925 Capra hircus Mammals 548460973 XP_005678619.1 488 488 yes 1747955 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 13333 Amborella trichopoda Plants UP000017836 586644112, 548831534 ERM94342.1 XP_006827105.1 454 464 yes 1747956 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 747089 Glomus intraradices DAOM 181602 Fungi UP000018888 552918451 ESA03370.1 417 438 yes 1747957 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 77166 Dendroctonus ponderosae Invertebrates UP000030742 546683207 ERL93047.1 400 404 yes 1747958 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1391915 Sporothrix schenckii ATCC 58251 Fungi UP000018087 550806473 ERS98388.1 562 562 yes 1747959 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8083 Xiphophorus maculatus Vertebrates UP000002852 551520082 XP_005811533.1 490 490 yes 1747960 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8083 Xiphophorus maculatus Vertebrates UP000002852 551505235 XP_005804152.1 420 432 yes 1747961 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9615 Canis lupus familiaris Mammals UP000002254 UP000002254 545512164 XP_005624999.1 147 180 no 1747962 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9796 Equus caballus Mammals UP000002281 UP000002281 545207886 XP_005607178.1 261 261 no 1747963 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9615 Canis lupus familiaris Mammals UP000002254 UP000002254 545512162 XP_005624998.1 143 187 no 1747964 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9823 Sus scrofa Mammals UP000008227 UP000008227 545836644 XP_003482155.2 87 91 no 1747965 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1432141, 747089 Rhizophagus irregularis DAOM 197198w, Glomus intraradices DAOM 181602 Fungi UP000022910, UP000018888 595481076, 552929002 EXX69248.1, ESA12876.1 424 425 yes 1747966 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 303518 Pundamilia nyererei Vertebrates 548438379 XP_005744928.1 500 500 yes 1747967 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9925 Capra hircus Mammals 548507474 XP_005693377.1 420 433 yes 1747968 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1076935 Pyronema omphalodes CBS100304 Fungi UP000018144 549053166 597 609 yes 1747969 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 229980, 1198449 Aeropyrum camini, Aeropyrum camini SY1 = JCM 12091 Archaea UP000016887 549634864, 549454971, 547221556 WP_022541073.1, YP_008603730.1 U3TBJ8 U3TBJ8_9CREN 345 354 no 1758655 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6210 Echinococcus granulosus Invertebrates UP000019149 674561779 414 425 yes 1758656 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8153 Haplochromis burtoni Vertebrates 554843396 XP_005932074.1 415 428 yes 1758657 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 225164 Lottia gigantea Invertebrates UP000030746 676484335, 556097416 ESO86068.1 XP_009063313.1 483 483 yes 1758658 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 225164 Lottia gigantea Invertebrates UP000030746 676448597, 556109292 ESO97944.1 XP_009051784.1 428 436 yes 1758659 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7897 Latimeria chalumnae Vertebrates UP000008672 557018125, 557018123 XP_006009450.1, XP_006009449.1 497 508 yes 1758660 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 85681 Citrus clementina Plants UP000030687 567879851, 557534606 ESR45724.1 XP_006432484.1 435 438 yes 1758661 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6210 Echinococcus granulosus Invertebrates UP000019149 674564365 452 456 yes 1758662 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 85433 Hymenolepis microstoma Invertebrates UP000017242 674590518 416 425 yes 1758663 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 72664 Eutrema salsugineum Plants UP000030689 567183396, 557103772 ESQ44126.1 XP_006402673.1 441 442 yes 1758664 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1431545, 1324957 Candidatus Halobonum tyrrellensis, Halobacteriaceae archaeon G22 Archaea 557372649, 556697952 ESP89154.1 WP_023393709.1 V4HMJ9 V4HMJ9_9EURY 344 345 no 1758665 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7897 Latimeria chalumnae Vertebrates UP000008672 557018121 XP_006009448.1 497 512 yes 1758666 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5801 Eimeria acervulina Invertebrates UP000018050 557121703 638 638 no 1758667 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7897 Latimeria chalumnae Vertebrates UP000008672 557013933 XP_006007491.1 239 245 no 1758668 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 109478 Myotis brandtii Mammals UP000052978 554527147 XP_005858400.1 418 442 yes 1758669 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 59538 Pantholops hodgsonii Mammals 556760989 XP_005975808.1 354 363 yes 1758670 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 109478 Myotis brandtii Mammals UP000052978 554544179 XP_005866683.1 261 261 no 1758671 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1412873 uncultured archaeon A07HN63 Archaea UP000030667 557615924 ESS09469.1 V4XM42 V4XM42_9ARCH 242 281 no 1758672 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1410576 uncultured Acidilobus sp. JCHS Archaea UP000018188 557078578 ESQ24411.1 V4LZT2 V4LZT2_9CREN 326 343 no 1758673 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 72664 Eutrema salsugineum Plants UP000030689 567163631, 557098121 ESQ38557.1 XP_006397104.1 485 485 yes 1758674 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 51315 Eimeria necatrix Invertebrates UP000030754 557160500 455 460 no 1758675 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 85433 Hymenolepis microstoma Invertebrates UP000017242 674592463 460 462 yes 1758676 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6412 Helobdella robusta Invertebrates UP000015101 675891100, 555687616 ESN90848.1 XP_009031052.1 489 490 yes 1758677 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8153 Haplochromis burtoni Vertebrates 554872259, 554872257 XP_005946073.1, XP_005946072.1 494 494 yes 1758678 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1381753 Moniliophthora roreri MCA 2997 Fungi UP000017559 630174479, 554916418 ESK97467.1 XP_007843219.1 517 521 no 1758679 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1410573 uncultured Acidilobus sp. MG Archaea UP000017902 557077008 ESQ22886.1 V4LV12 V4LV12_9CREN 326 343 no 1758680 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7897 Latimeria chalumnae Vertebrates UP000008672 557021130 XP_006010867.1 225 231 no 1758681 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 59538 Pantholops hodgsonii Mammals 556740861 XP_005965970.1 489 489 yes 1758682 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1410574 uncultured Acidilobus sp. CIS Archaea UP000017934 557075905 ESQ21822.1 V4JWX9 V4JWX9_9CREN 333 343 no 1758683 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1410575 uncultured Acidilobus sp. OSP8 Archaea UP000018061 557079623 ESQ25434.1 V4K371 V4K371_9CREN 326 343 no 1758684 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6412 Helobdella robusta Invertebrates UP000015101 675873238, 555696600 ESN99832.1 XP_009022179.1 435 441 yes 1758685 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6412 Helobdella robusta Invertebrates UP000015101 675872936, 555696603 ESN99835.1 XP_009022028.1 371 378 yes 1758686 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1412871 uncultured archaeon A07HR67 Archaea UP000030660 557609692 ESS03288.1 V4XMQ7 V4XMQ7_9ARCH 344 346 no 1758687 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 38654 Alligator sinensis Vertebrates 557319547 XP_006032937.1 382 412 yes 1758688 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 38654 Alligator sinensis Vertebrates 557260521 XP_006015904.1 200 204 no 1758689 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1412874 uncultured archaeon A07HR60 Archaea UP000030679 557617259 ESS10788.1 V4Y7E2 V4Y7E2_9ARCH 343 347 no 1758690 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 59538 Pantholops hodgsonii Mammals 556740863 XP_005965971.1 261 261 no 1758691 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1412872 uncultured archaeon A07HB70 Archaea UP000030648 557612663 ESS06242.1 V4Y5E2 V4Y5E2_9ARCH 358 397 no 1758692 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2711, 85681 Citrus sinensis, Citrus clementina Plants UP000027120, UP000030687 568850137, 568850135, 567900742, 567900740, 557545121, 557545120 ESR56099.1, ESR56098.1 XP_006478783.1, XP_006478782.1, XP_006442859.1, XP_006442858.1 424 427 yes 1758693 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1381753 Moniliophthora roreri MCA 2997 Fungi UP000017559 630193571, 554909820 ESK91334.1 XP_007849364.1 504 505 yes 1758694 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 72664 Eutrema salsugineum Plants UP000030689 567138230, 557091081 ESQ31728.1 XP_006394442.1 449 464 yes 1758695 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming superfamily sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 51314 Eimeria brunetti Invertebrates UP000030750 557211135 706 707 no 1856747 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1043628 Drechslerella stenobrocha 248 Fungi UP000024837 582958095 EWC46306.1 546 546 yes 1856748 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1237626 Plasmodium inui San Antonio 1 Invertebrates UP000030640 672196532, 577143046 EUD66427.1 XP_008816875.1 709 710 no 1856749 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 122 126 no 1856750 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 409 410 no 1856751 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7460 Apis mellifera Invertebrates UP000005203 571540652 XP_006568418.1 315 318 no 1856752 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 724 724 yes 1856753 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 134006 Phytomonas sp. isolate EM1 Environmental samples UP000027080 588319918 769 771 no 1856754 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1220924 Phialophora europaea CBS 101466 Fungi UP000030752 671161597, 568115823 ETN38443.1 XP_008719032.1 547 547 yes 1856755 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1379702 Methanobacterium sp. MB1 Archaea UP000017867 566005921, 557947398 WP_023993031.1 U6EDF0 U6EDF0_9EURY 328 329 no 1856756 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 334819 Gibberella moniliformis 7600 Fungi UP000009096 584127199 EWG36618.1 448 454 yes 1856757 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1080344 Fusarium oxysporum f. sp. pisi HDV247 Fungi UP000030751 587754282 EXA51998.1 444 453 yes 1856758 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 909455 Fusarium oxysporum FOSC 3-a Fungi UP000030753 587670610 EWY92951.1 445 453 yes 1856759 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3885 Phaseolus vulgaris Plants UP000000226 593787988, 561030448 ESW29027.1 XP_007157033.1 460 461 yes 1856760 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5741 Giardia intestinalis Invertebrates UP000018320 559179173 ESU41220.1 369 384 no 1856761 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9713 Leptonychotes weddellii Mammals 585196484 XP_006749351.1 261 261 no 1856762 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9713 Leptonychotes weddellii Mammals 585196482 XP_006749350.1 489 489 yes 1856763 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7918 Lepisosteus oculatus Vertebrates UP000018468 573894085 XP_006634793.1 500 500 yes 1856764 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 185453 Chrysochloris asiatica Mammals 586465351 XP_006863297.1 418 438 yes 1856765 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 353800, 797299 Halostagnicola larsenii, Halostagnicola larsenii XH-48 Archaea UP000019024 909709419, 573481005 AHF99415.1 WP_049952617.1 W0JL02 W0JL02_9EURY 348 349 no 1856766 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7460 Apis mellifera Invertebrates UP000005203 571540272 XP_006568369.1 499 574 yes 1856767 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7370 Musca domestica Invertebrates 557782150 XP_005190690.1 461 473 yes 1856768 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 441 456 yes 1856769 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3847 Glycine max Plants UP000008827 UP000008827 571491927 XP_006592079.1 460 462 yes 1856770 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1036727 Plasmodium falciparum MaliPS096_E11 Invertebrates UP000030699 574985495 ETW46833.1 686 686 yes 1856771 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9713 Leptonychotes weddellii Mammals 585179570 XP_006741461.1 420 435 yes 1856772 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 756 756 yes 1856773 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 112090 Aphanomyces astaci Plants UP000019040 698780697, 574121116 ETV86593.1 XP_009823392.1 420 422 yes 1856774 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 59463 Myotis lucifugus Mammals UP000001074 558118189 XP_006087260.1 473 473 yes 1856775 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6210 Echinococcus granulosus Invertebrates UP000019149 576693184 EUB56805.1 420 483 yes 1856776 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1382522 Kuraishia capsulata CBS 1993 Fungi UP000019384 584395035 583 589 yes 1856777 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1043628 Drechslerella stenobrocha 248 Fungi UP000024837 582959339 EWC47540.1 420 420 yes 1856778 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 312017 Tetrahymena thermophila SB210 Invertebrates UP000009168 UP000009168 829192112, 586728561 EDK31402.2 XP_001471008.2 431 437 yes 1856779 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8665 Ophiophagus hannah Vertebrates UP000018936 565307529 ETE61757.1 406 572 no 1856780 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1391700 Pseudozyma aphidis DSM70725 Fungi UP000019462 573028791 ETS62018.1 587 590 no 1856781 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1086054 Rhizoctonia solani AG-3 Rhs1AP Fungi UP000030108 576993668 EUC66334.1 487 493 no 1856782 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 114 155 no 1856783 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8496 Alligator mississippiensis Vertebrates UP000050525 564232590 XP_006260672.1 374 412 yes 1856784 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 134006 Phytomonas sp. isolate EM1 Environmental samples UP000027080 588320947 366 368 yes 1856785 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 930089 Cochliobolus carbonum 26-R-13 Fungi UP000053841 628236224, 576914097 EUC28476.1 XP_007717221.1 461 475 yes 1856786 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1279043 Cladophialophora carrionii CBS 160.54 Fungi UP000030678 671182852, 565930197 ETI19528.1 XP_008731887.1 436 447 yes 1856787 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2221, 1090322 Methanolobus tindarius, Methanolobus tindarius DSM 2278 Archaea 564599698, 563512288 ETA67662.1 WP_023844798.1 W9DVH6 W9DVH6_METTI 330 331 no 1856788 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1407055 Thaumarchaeota archaeon N4 Archaea 851356577, 563489773 WP_048194483.1 V6ARC3 V6ARC3_9ARCH 322 331 no 1856789 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1317066 Phytophthora parasitica P1976 Plants UP000028582 570315327 ETO63275.1 518 518 yes 1856790 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10224 Saccoglossus kowalevskii Invertebrates 585681171 XP_006819822.1 494 497 yes 1856791 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 30538 Lama pacos Mammals 560984595 XP_006214510.1 415 438 yes 1856792 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9402 Pteropus alecto Mammals UP000010552 586540614 XP_006925137.1 433 440 yes 1856793 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 246437 Tupaia chinensis Mammals UP000011518 562879900 XP_006167619.1 425 438 yes 1856794 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 30538 Lama pacos Mammals 560955902 XP_006200437.1 489 489 yes 1856795 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3885 Phaseolus vulgaris Plants UP000000226 593791264, 561032086 ESW30665.1 XP_007158671.1 191 193 no 1856796 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 533 541 yes 1856797 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13735 Pelodiscus sinensis Vertebrates UP000007267 558183012 XP_006127704.1 286 286 no 1856798 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 744 744 yes 1856799 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 660027, 1080343 Fusarium oxysporum Fo47, Fusarium oxysporum f. sp. lycopersici MN25 Fungi UP000030766, UP000030749 587699078, 587726162 EWZ45683.1, EWZ97499.1 536 536 yes 1856800 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 930091 Cochliobolus victoriae FI3 Fungi UP000054337 578490628 EUN28042.1 577 579 yes 1856801 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1365484 Penicillium roqueforti FM164 Fungi UP000030686 584409453 568 569 yes 1856802 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4113 Solanum tuberosum Plants UP000011115 565400922 XP_006365966.1 476 481 yes 1856803 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1323249 Plasmodium yoelii 17X Invertebrates UP000018538 564278300 ETB59719.1 668 669 yes 1856804 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1317064 Phytophthora parasitica P10297 Plants UP000018948 570971163 ETP34282.1 423 428 no 1856805 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1432307 Sclerotinia borealis F-4157 Fungi UP000019487 563291606 ESZ92105.1 435 446 yes 1856806 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1229662 Pestalotiopsis fici W106-1 Fungi UP000030651 630038617, 573055050 ETS74985.1 XP_007840241.1 597 597 yes 1856807 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3885 Phaseolus vulgaris Plants UP000000226 593700619, 561024012 ESW22742.1 XP_007150748.1 500 501 yes 1856808 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 930090 Cochliobolus miyabeanus ATCC 44560 Fungi UP000054032 627916469, 576928141 EUC41795.1 XP_007691684.1 578 580 yes 1856809 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 930090 Cochliobolus miyabeanus ATCC 44560 Fungi UP000054032 627825907, 576934771 EUC48282.1 XP_007685210.1 462 475 yes 1856810 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 51031 Necator americanus Invertebrates UP000053676 915260967, 568288917 ETN77226.1 XP_013299453.1 197 217 no 1856811 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7462 Apis dorsata Invertebrates 572318808 XP_006624968.1 493 574 yes 1856812 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1323249 Plasmodium yoelii 17X Invertebrates UP000018538 564278111 ETB59530.1 470 475 yes 1856813 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1416333 Trypanosoma cruzi Dm28c Invertebrates UP000017861 557866390 ESS69589.1 618 620 no 1883230 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1326980 Sulfolobales archaeon AZ1 Archaea UP000054284 851366446, 780150711, 583848101 KJR78912.1, EWG07795.1 WP_048199470.1 W7KK96 W7KK96_9CREN 326 331 no 1883231 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 72520 Nannochloropsis gaditana Plants UP000019335 585112601 EWM29993.1 415 420 yes 1883232 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1080344 Fusarium oxysporum f. sp. pisi HDV247 Fungi UP000030751 587753242 EXA50958.1 536 536 yes 1883233 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7918 Lepisosteus oculatus Vertebrates UP000018468 573906889 XP_006641164.1 448 517 no 1883234 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5741 Giardia intestinalis Invertebrates UP000018320 559176376 ESU38925.1 369 393 no 1883235 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6210 Echinococcus granulosus Invertebrates UP000019149 576692171 EUB55831.1 441 449 yes 1883236 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 134013 Phytomonas sp. isolate Hart1 Environmental samples UP000053358 594149256 367 369 yes 1883237 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5518 Gibberella zeae Fungi UP000022177 596544082 EYB24295.1 454 462 yes 1883238 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 53326 Ancylostoma ceylanicum Invertebrates UP000054495 597858992 EYC08417.1 176 207 no 1883239 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1237627 Plasmodium falciparum UGT5.1 Invertebrates UP000030697 583212166 EWC73933.1 720 720 yes 1883240 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182543 Cladophialophora psammophila CBS 110553 Fungi UP000019471 628331549, 589987868 EXJ70726.1 XP_007744505.1 438 447 yes 1883241 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1445577 Colletotrichum fioriniae PJ7 Fungi UP000020467 615468705, 588894003 EXF76060.1 XP_007600319.1 514 514 yes 1883242 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 334819 Gibberella moniliformis 7600 Fungi UP000009096 584145381 EWG54652.1 536 536 yes 1883243 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 134013 Phytomonas sp. isolate Hart1 Environmental samples UP000053358 594144186 774 779 no 1883244 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6289 Haemonchus contortus Invertebrates UP000025227 560132189 394 395 yes 1883245 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 582419 Thermococcus sp. ES1 Archaea UP000019027 757127754, 573025566 AHF81100.1 WP_042682087.1 W0I9G0 W0I9G0_9EURY 339 346 no 1883246 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 310752 Balaenoptera acutorostrata scammoni Mammals 594658434 XP_007177531.1 422 438 yes 1883247 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 310752 Balaenoptera acutorostrata scammoni Mammals 594658436 XP_007177532.1 368 387 yes 1883248 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8496 Alligator mississippiensis Vertebrates UP000050525 564255292 XP_006266621.1 339 339 no 1883249 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 310752 Balaenoptera acutorostrata scammoni Mammals 594658438 XP_007177533.1 348 363 yes 1883250 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8469 Chelonia mydas Vertebrates UP000031443 591373803 XP_007061596.1 365 366 yes 1883251 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 478859 Plasmodium falciparum Santa Lucia Invertebrates UP000030666 579327851 EUT78791.1 726 726 yes 1883252 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 930089 Cochliobolus carbonum 26-R-13 Fungi UP000053841 628218916, 576916961 EUC31200.1 XP_007714501.1 577 579 yes 1883253 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1365484 Penicillium roqueforti FM164 Fungi UP000030686 584406862 430 435 yes 1883254 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 59463 Myotis lucifugus Mammals UP000001074 558171802 XP_006099233.1 405 438 yes 1883255 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 157072 Aphanomyces invadans Plants UP000024375 673024674, 574477864 ETW04860.1 XP_008866298.1 417 418 yes 1883256 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 185453 Chrysochloris asiatica Mammals 586455839 XP_006839740.1 489 489 yes 1883257 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1089448 Fusarium oxysporum f. sp. radicis-lycopersici 26381 Fungi UP000030657 591427898 EXL63035.1 536 536 yes 1883258 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4113 Solanum tuberosum Plants UP000011115 565344184 XP_006339197.1 497 498 yes 1883259 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 7994 Astyanax mexicanus Vertebrates UP000018467 597764281 XP_007246064.1 361 368 no 1883260 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6289 Haemonchus contortus Invertebrates UP000025227 560125119, 560118367 208 231 no 1883261 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1036727 Plasmodium falciparum MaliPS096_E11 Invertebrates UP000030699 574985665 ETW47001.1 482 487 yes 1883262 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1382522 Kuraishia capsulata CBS 1993 Fungi UP000019384 584394571 422 427 yes 1883263 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 312017 Tetrahymena thermophila SB210 Invertebrates UP000009168 UP000009168 829186383, 586731700 EAS02058.2 XP_001022303.2 460 461 yes 1883264 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1388766 Aspergillus rubrum CBS 135680 Fungi UP000019804 599158662 EYE97723.1 431 435 yes 1883265 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1220924 Phialophora europaea CBS 101466 Fungi UP000030752 671379872, 568115035 ETN37656.1 XP_008719825.1 435 445 yes 1883266 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 225400 Myotis davidii Mammals UP000010556 584046812 XP_006768197.1 422 451 yes 1883267 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182541 Capronia coronata CBS 617.96 Fungi UP000019484 628274854, 590003222 EXJ78438.1 XP_007727886.1 435 445 yes 1883268 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6289 Haemonchus contortus Invertebrates UP000025227 560125122, 560118370 172 175 no 1883269 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6289 Haemonchus contortus Invertebrates UP000025227 560118371 160 340 no 1883270 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4533 Oryza brachyantha Plants UP000006038 573923171 XP_006649166.1 475 478 yes 1883271 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 51031 Necator americanus Invertebrates UP000053676 568288920 ETN77229.1 213 313 no 1883272 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 32507 Neolamprologus brichardi Vertebrates 584023535 XP_006806404.1 494 494 yes 1883273 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294382, 1294346, 1294310, 947042, 1296266, 1177187, 1182966 Saccharomyces cerevisiae YJM1526, Saccharomyces cerevisiae YJM1311, Saccharomyces cerevisiae YJM450, Saccharomyces cerevisiae YJM320, Saccharomyces cerevisiae YJM1078, Saccharomyces cerevisiae P283, Saccharomyces cerevisiae R008 Fungi UP000032927, UP000033178, UP000032960, UP000032952, UP000032926, UP000019320, UP000025243 767180909, 767168244, 767023150, 767012184, 761508667, 584475725, 584364674 AJS55117.1, AJS44387.1, AJS33053.1, AJS32150.1, AJP39859.1, EWH17479.1, EWG84679.1 528 534 yes 1883274 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 348837 Spironucleus salmonicida Invertebrates UP000018208 558600628 EST47479.1 331 339 no 1883275 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182544 Cladophialophora yegresii CBS 114405 Fungi UP000019473 628315318, 589970714 EXJ54072.1 XP_007761587.1 437 447 yes 1883276 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 89462 Bubalus bubalis Mammals 594031585 XP_006040606.1 127 128 no 1883277 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10090 Mus musculus Rodents UP000000589 UP000000589 568929603 XP_006503394.1 413 413 yes 1883278 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2711 Citrus sinensis Plants UP000027120 568880814 XP_006493302.1 432 436 yes 1883279 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9685 Felis catus Mammals UP000011712 UP000011712 586995350 XP_006934738.1 362 407 no 1883280 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1089452, 426428 Fusarium oxysporum f. sp. melonis 26406, Fusarium oxysporum f. sp. lycopersici 4286 Fungi UP000030703, UP000009097 590041242 EXK43100.1 A0A0D2YGP2 A0A0D2YGP2_FUSO4 536 536 yes 1883281 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3847 Glycine max Plants UP000008827 UP000008827 571514549 XP_006597121.1 490 490 yes 1883282 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1356009 Byssochlamys spectabilis No. 5 Fungi UP000018001 557727377 569 570 yes 1883283 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 72520 Nannochloropsis gaditana Plants UP000019335 585110970 EWM28552.1 543 544 yes 1883284 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1445577 Colletotrichum fioriniae PJ7 Fungi UP000020467 615463086, 588896344 EXF77836.1 XP_007598557.1 442 449 yes 1883285 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8665 Ophiophagus hannah Vertebrates UP000018936 565316816 ETE68404.1 476 477 yes 1883286 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 53326 Ancylostoma ceylanicum Invertebrates UP000054495 597835084 EYB84753.1 390 398 yes 1883287 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 53326 Ancylostoma ceylanicum Invertebrates UP000054495 597835083, 510861087 EYB84752.1, EPB76517.1 389 395 yes 1883288 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 157072 Aphanomyces invadans Plants UP000024375 673027412, 574476440 ETW03438.1 XP_008867667.1 477 829 yes 1883289 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182542 Capronia epimyces CBS 606.96 Fungi UP000019478 628305555, 590007312 EXJ82520.1 XP_007734643.1 428 445 yes 1883290 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1317063 Phytophthora parasitica CJ01A1 Plants UP000018958 570939118 ETP04375.1 518 518 yes 1883291 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1355161 Zygosaccharomyces bailii ISA1307 Fungi UP000032161 578053276 424 424 yes 1883292 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 89462 Bubalus bubalis Mammals 594037302 XP_006043289.1 261 261 no 1883293 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 89462 Bubalus bubalis Mammals 594037300 XP_006043288.1 489 489 yes 1883294 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9685 Felis catus Mammals UP000011712 UP000011712 586995348 XP_003990054.2 494 539 yes 1883295 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 761204, 1317063, 1317066, 4792, 1317065 Phytophthora parasitica INRA-310, Phytophthora parasitica CJ01A1, Phytophthora parasitica P1976, Phytophthora parasitica, Phytophthora parasitica P1569 Plants UP000018817, UP000018958, UP000028582, UP000053236, UP000018721 675174261, 570940925, 570317115, 568103667, 568038939, 568009019, 567979533, 567950862, 566013431 ETP06182.1, ETO65063.1, ETN18324.1, ETM36453.1, ETL83233.1, ETL30012.1, ETK76569.1, ETI36342.1 XP_008896015.1 404 406 yes 1883296 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 761204, 1317066, 4792, 1317065 Phytophthora parasitica INRA-310, Phytophthora parasitica P1976, Phytophthora parasitica, Phytophthora parasitica P1569 Plants UP000018817, UP000028582, UP000053236, UP000018721 675174259, 570317114, 568103666, 568038938, 566013430 ETO65062.1, ETN18323.1, ETM36452.1, ETI36341.1 XP_008896014.1 435 440 yes 1883297 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 230844 Peromyscus maniculatus bairdii Rodents 589929252 XP_006977441.1 423 440 yes 1883298 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9755 Physeter catodon Mammals 593770405 XP_007123585.1 423 438 yes 1883299 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9755 Physeter catodon Mammals 593770403 XP_007123584.1 422 444 yes 1883300 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182544 Cladophialophora yegresii CBS 114405 Fungi UP000019473 628281555, 589982129 EXJ65370.1 XP_007753937.1 578 578 yes 1883301 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1432141 Rhizophagus irregularis DAOM 197198w Fungi UP000022910 595481077 EXX69249.1 328 329 yes 1883302 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 51031 Necator americanus Invertebrates UP000053676 568299308 ETN85192.1 226 228 no 1883303 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 470 470 yes 1883304 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7370 Musca domestica Invertebrates 557759836 XP_005179642.1 490 490 yes 1883305 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8469 Chelonia mydas Vertebrates UP000031443 591365978 XP_007057850.1 456 611 yes 1883306 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1344414 Trichoderma reesei RUT C-30 Fungi UP000024376 572282678 ETS05692.1 457 846 yes 1883307 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1003335 Kluyveromyces marxianus DMKU3-1042 Fungi UP000065495 574144668 422 426 yes 1883308 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1317064 Phytophthora parasitica P10297 Plants UP000018948 570969365 ETP32484.1 518 518 yes 1883309 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182541 Capronia coronata CBS 617.96 Fungi UP000019484 628220669, 590020895 EXJ96092.1 XP_007720321.1 571 571 yes 1883310 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1279043 Cladophialophora carrionii CBS 160.54 Fungi UP000030678 671167716, 565937834 ETI27011.1 XP_008724324.1 570 570 yes 1883311 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1365824 Pseudozyma hubeiensis GHG001 Fungi UP000019377 557995804 EST05344.1 599 604 no 1883312 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182967 Saccharomyces cerevisiae R103 Fungi UP000027126 584375558 EWG95439.1 423 425 yes 1883313 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 909455 Fusarium oxysporum FOSC 3-a Fungi UP000030753 587677331 EWY99659.1 536 536 yes 1883314 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1080343 Fusarium oxysporum f. sp. lycopersici MN25 Fungi UP000030749 587715876 EWZ87213.1 445 453 yes 1883315 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 32507 Neolamprologus brichardi Vertebrates 584013657 XP_006801619.1 415 428 yes 1883316 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 74533 Panthera tigris altaica Mammals 591300862 XP_007077380.1 493 537 yes 1883317 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 112090 Aphanomyces astaci Plants UP000019040 698784373, 574119733 ETV85212.1 XP_009825230.1 505 531 yes 1883318 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182543 Cladophialophora psammophila CBS 110553 Fungi UP000019471 628332835, 589988254 EXJ71112.1 XP_007744891.1 576 576 yes 1883319 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 74533 Panthera tigris altaica Mammals 591298244 XP_007076184.1 421 440 yes 1883320 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 57266 Plasmodium falciparum 7G8 Invertebrates UP000030688 579114862 EUR63581.1 723 723 yes 1883321 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 138298 Plasmodium vinckei petteri Invertebrates UP000030659 577150815 EUD73869.1 674 675 yes 1883322 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1036724 Plasmodium falciparum FCH/4 Invertebrates UP000030656 574965545 ETW28768.1 728 1491 yes 1883323 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4792 Phytophthora parasitica Plants UP000053236 567977767 ETL28264.1 518 518 yes 1883324 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4533 Oryza brachyantha Plants UP000006038 573962412 XP_006663353.1 446 448 no 1883325 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 747525 Heterobasidion annosum TC 32-1 Fungi UP000030671 695541233, 575068235 ETW83847.1 XP_009543227.1 461 463 no 1883326 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 310752 Balaenoptera acutorostrata scammoni Mammals 594619861 XP_007164658.1 489 489 yes 1883327 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1388766 Aspergillus rubrum CBS 135680 Fungi UP000019804 599160693 EYE99643.1 572 572 yes 1883328 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28737 Elephantulus edwardii Mammals 585661603 XP_006886620.1 489 489 yes 1883329 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2285, 1435377 Sulfolobus acidocaldarius, Sulfolobus acidocaldarius SUSAZ Archaea UP000065473, UP000060777 568208565, 566046799 AHC50684.1 WP_024082929.1 V9S6Q1 V9S6Q1_9CREN 331 334 no 1883330 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1089449 Fusarium oxysporum f. sp. vasinfectum 25433 Fungi UP000030701 591506390 EXM35653.1 536 536 yes 1883331 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1229662 Pestalotiopsis fici W106-1 Fungi UP000030651 630025890, 573059196 ETS78994.1 XP_007835619.1 429 442 yes 1883332 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 655844, 568076 Metarhizium anisopliae ARSEF 23, Metarhizium robertsii Fungi UP000002498, UP000030151 761842321, 734843180, 594722566 KHO11777.1, EXV05452.1 XP_011410741.1 452 454 yes 1883333 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7994 Astyanax mexicanus Vertebrates UP000018467 597736252, 597736250 XP_007230387.1, XP_007230386.1 497 499 yes 1883334 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 53326 Ancylostoma ceylanicum Invertebrates UP000054495 597859002 EYC08427.1 283 288 no 1883335 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 53326 Ancylostoma ceylanicum Invertebrates UP000054495 597859001 EYC08426.1 268 271 no 1883336 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1432307 Sclerotinia borealis F-4157 Fungi UP000019487 563294528 ESZ94825.1 565 565 yes 1883337 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28737 Elephantulus edwardii Mammals 585678314 XP_006891160.1 413 438 yes 1883338 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1356009 Byssochlamys spectabilis No. 5 Fungi UP000018001 557726851 442 446 yes 1883339 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4792, 1317065 Phytophthora parasitica, Phytophthora parasitica P1569 Plants UP000053236, UP000018721 568037119, 566011560 ETM34713.1, ETI34471.1 518 518 yes 1883340 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 930091 Cochliobolus victoriae FI3 Fungi UP000054337 578483817 EUN21366.1 461 475 yes 1883341 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1036725 Plasmodium falciparum Tanzania (2000708) Invertebrates UP000030708 574971833 ETW34089.1 524 527 no 1883342 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 981085 Morus notabilis Plants UP000030645 703133684, 703120733, 587965725, 587904214 EXC50896.1, EXB92415.1 XP_010105452.1, XP_010102165.1 459 464 yes 1883343 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13735 Pelodiscus sinensis Vertebrates UP000007267 558200280 XP_006131348.1 276 380 no 1883344 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 46433 Reticulomyxa filosa Invertebrates UP000023152 569418322 ETO27629.1 590 606 yes 1883345 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1365824 Pseudozyma hubeiensis GHG001 Fungi UP000019377 557997573 EST07045.1 561 562 yes 1883346 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4792 Phytophthora parasitica Plants UP000053236 568007246 ETL81487.1 517 874 yes 1883347 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2711 Citrus sinensis Plants UP000027120 568850132 XP_006478781.1 495 495 yes 1883348 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4792 Phytophthora parasitica Plants UP000053236 567949104 ETK74838.1 510 1005 yes 1883349 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 53326 Ancylostoma ceylanicum Invertebrates UP000054495 597858994 EYC08419.1 213 223 no 1883350 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 53326 Ancylostoma ceylanicum Invertebrates UP000054495 597858993 EYC08418.1 214 235 no 1883351 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182542 Capronia epimyces CBS 606.96 Fungi UP000019478 628322547, 590004082 EXJ79297.1 XP_007737085.1 564 565 yes 1883352 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1317063, 4792 Phytophthora parasitica CJ01A1, Phytophthora parasitica Plants UP000018958, UP000053236 570940924, 568009018, 567979532 ETP06181.1, ETL83232.1, ETL30011.1 435 440 yes 1883353 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 230844 Peromyscus maniculatus bairdii Rodents 589969428 XP_006997197.1 489 489 yes 1883354 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1003335 Kluyveromyces marxianus DMKU3-1042 Fungi UP000065495 574140461 590 591 yes 1883355 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 761204 Phytophthora parasitica INRA-310 Plants UP000018817 675176033, 568102656 ETN17327.1 XP_008896901.1 522 525 yes 1883356 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 89462 Bubalus bubalis Mammals 594114278 XP_006079867.1 415 438 no 1883357 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9755 Physeter catodon Mammals 593732998 XP_007111975.1 489 489 yes 1883358 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 747525 Heterobasidion annosum TC 32-1 Fungi UP000030671 695573328, 575061052 ETW76672.1 XP_009551553.1 525 525 yes 1883359 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 138298 Plasmodium vinckei petteri Invertebrates UP000030659 577150678 EUD73732.1 471 476 yes 1883360 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9837, 419612 Camelus bactrianus, Camelus ferus Mammals UP000030684 743696419, 560904321 XP_010947182.1, XP_006178523.1 489 489 yes 1883361 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1036726 Plasmodium falciparum NF135/5.C10 Invertebrates UP000019114 574978146 ETW39991.1 710 710 yes 1883362 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1086054 Rhizoctonia solani AG-3 Rhs1AP Fungi UP000030108 576991358 EUC64060.1 491 500 yes 1883363 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4792 Phytophthora parasitica Plants UP000053236 567950861 ETK76568.1 436 440 yes 1883364 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 195522 Thermococcus nautilus Archaea UP000019434 757138257, 589910569 AHL23618.1 WP_042692505.1 W8NWE0 W8NWE0_9EURY 330 344 no 1883365 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7462 Apis dorsata Invertebrates 572300629 XP_006616401.1 455 464 yes 1883366 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 419612 Camelus ferus Mammals UP000030684 560917759 XP_006185119.1 348 388 yes 1883367 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 981085 Morus notabilis Plants UP000030645 703090553, 587865672 EXB55202.1 XP_010094112.1 494 497 yes 1883368 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1237626 Plasmodium inui San Antonio 1 Invertebrates UP000030640 672199177, 577142585 EUD65989.1 XP_008817527.1 485 489 yes 1887402 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1215338, 1215336 Trichophyton interdigitale MR816, Trichophyton rubrum H6 Fungi UP000024533, UP000053242 633049455, 607897766 KDB25630.1, EZF36082.1 604 604 yes 1887403 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 176946 Python molurus bivittatus Vertebrates 602676487 XP_007443708.1 342 344 yes 1887404 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4155 Mimulus guttatus Plants UP000030748 848891036, 604319269 EYU30525.1 XP_012845640.1 480 483 yes 1887405 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 13616 Monodelphis domestica Mammals UP000002280 UP000002280 612001718 XP_007485825.1 401 443 yes 1887406 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9365 Erinaceus europaeus Mammals 617655191 XP_007535357.1 261 261 no 1887407 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 118797 Lipotes vexillifer Mammals 602684019 XP_007454264.1 423 438 yes 1887408 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9365 Erinaceus europaeus Mammals 617655188 XP_007535356.1 488 488 yes 1887409 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 176946 Python molurus bivittatus Vertebrates 602626137 XP_007420030.1 477 477 yes 1887410 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1215332 Trichophyton megninii CBS 735.88 Fungi UP000024377 607978087 EZG07184.1 602 603 yes 1887411 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1215341 Trichophyton rubrum MR1459 Fungi UP000023676 607965970 EZF96245.1 545 545 yes 1887412 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1160895 Acidianus sp. ALE_1 Archaea 851185853, 612170330 EZQ06951.1 WP_048099475.1 A0A031LPM7 A0A031LPM7_9CREN 330 332 no 1887413 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1215338, 1215336 Trichophyton interdigitale MR816, Trichophyton rubrum H6 Fungi UP000024533, UP000053242 633047421, 607892165 KDB23915.1, EZF31634.1 429 440 yes 1887414 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 443821 Cerapachys biroi Invertebrates UP000053097 759043789, 607364960 EZA59162.1 XP_011330790.1 407 410 yes 1887415 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 559305, 1215335, 1215334, 1215341, 1215339, 1215329, 1215330, 1215328, 1215337 Trichophyton rubrum CBS 118892, Trichophyton rubrum D6, Trichophyton raubitschekii CBS 202.88, Trichophyton rubrum MR1459, Trichophyton rubrum MR1448, Trichophyton kanei CBS 289.86, Trichophyton fischeri CBS 288.86, Trichophyton fischeri CBS 100081, Trichophyton rubrum MR850 Fungi UP000008864, UP000024976, UP000023645, UP000023676, UP000023756, UP000023661, UP000023758, UP000023688, UP000024696 674806763, 633057207, 607987200, 607963145, 607950815, 607927045, 607914893, 607902911, 607871082 EGD87225.2, KDB32183.1, EZG15264.1, EZF93648.1, EZF82789.1, EZF61678.1, EZF50963.1, EZF40455.1, EZF16319.1 383 391 yes 1887416 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4155 Mimulus guttatus Plants UP000030748 848911542, 604303962 EYU23312.1 XP_012854190.1 454 459 yes 1887417 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 69319 Microplitis demolitor Invertebrates 665789933, 607304642 EZA45735.1 XP_008560628.1 472 477 yes 1887418 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1215331 Trichophyton soudanense CBS 452.61 Fungi UP000023623 607938740 EZF72067.1 383 391 yes 1887419 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 48698 Poecilia formosa Vertebrates UP000028760 617407693 XP_007554412.1 404 420 yes 1887420 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9365 Erinaceus europaeus Mammals 617589977 XP_007520522.1 423 469 yes 1887421 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1215332 Trichophyton megninii CBS 735.88 Fungi UP000024377 607975498 EZG04728.1 383 391 yes 1887422 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 443821 Cerapachys biroi Invertebrates UP000053097 607357543 EZA51997.1 440 442 yes 1887423 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 48698 Poecilia formosa Vertebrates UP000028760 617407687 XP_007554411.1 418 432 yes 1887424 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 118797 Lipotes vexillifer Mammals 602716245 XP_007468321.1 489 489 yes 1887425 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 88036 Selaginella moellendorffii Plants UP000001514 302825870, 300137514 EFJ04427.1 XP_002994508.1 50 134 no 1887426 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 48698 Poecilia formosa Vertebrates UP000028760 617425140 XP_007559892.1 490 490 yes 1887427 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 48698 Poecilia formosa Vertebrates UP000028760 617425144 XP_007559893.1 467 467 yes 1887428 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 110365 Gregarina niphandrodes Invertebrates UP000019763 749162691, 608647872 EZG43853.1 XP_011132974.1 432 436 no 1887429 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 88036 Selaginella moellendorffii Plants UP000001514 302797068, 300151911 EFJ18555.1 XP_002980295.1 47 164 no 1919472 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 683840 Microbotryum violaceum p1A1 Lamole Fungi UP000017200 634352468 KDE07589.1 U5H404 U5H404_USTV1 560 560 yes 1919473 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1287689 Rhizoctonia solani AG-8 WAC10335 Fungi UP000027042 639572311 KDN49710.1 fig|3702.11.peg.13687 522 528 yes 1919474 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29078 Eptesicus fuscus Mammals 641719694, 641719692 XP_008149459.1, XP_008149458.1 fig|216594.1.peg.4558, fig|216594.6.peg.4776 489 489 yes 1919475 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5854 Plasmodium reichenowi Invertebrates UP000027581 832040358, 641578708 XP_012765342.1 fig|1001740.3.peg.5067, fig|1158135.4.peg.4734, fig|1149134.5.peg.2771, fig|1001724.3.peg.4738, fig|36809.5.peg.1020, fig|1162284.3.peg.4151, fig|1001722.3.peg.1266, fig|1001726.3.peg.814, fig|1001718.3.peg.809, fig|1001725.3.peg.1062, fig|1001738.3.peg.1132, fig|1001739.3.peg.956, fig|1001737.3.peg.1130, fig|1001716.3.peg.531, fig|1001723.3.peg.219, fig|1001727.3.peg.399, fig|1001736.3.peg.1481, fig|1001717.3.peg.986, fig|1001720.3.peg.995, fig|1001721.3.peg.942, fig|1001715.3.peg.1074, fig|1001741.3.peg.1126, fig|1001719.3.peg.568 733 733 yes 1919476 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2711 Citrus sinensis Plants UP000027120 641823113 KDO42555.1 fig|992132.3.peg.3685, fig|1084226.3.peg.2433, fig|1084228.3.peg.4201, fig|992172.3.peg.3458, fig|637382.3.peg.3834, fig|1084229.3.peg.2316, fig|992156.3.peg.3188, fig|992146.3.peg.3600, fig|349747.3.peg.3484, fig|404217.5.peg.3302, fig|547047.3.peg.3932, fig|1324608.3.peg.2717, fig|1324587.3.peg.2618, fig|1286087.3.peg.2358, fig|992158.3.peg.3414, fig|992142.3.peg.3514, fig|1084231.3.peg.3520, fig|992152.3.peg.3699, fig|992171.3.peg.3572, fig|992163.3.peg.3657, fig|992136.3.peg.3467, fig|992128.3.peg.3579, fig|187410.11.peg.968, fig|992159.3.peg.3243, fig|992147.3.peg.3608, fig|992144.3.peg.3481, fig|375450.5.peg.4129, fig|404216.5.peg.343, fig|404214.5.peg.1817, fig|992166.3.peg.3221, fig|1286086.3.peg.673, fig|547046.3.peg.1171, fig|1084232.3.peg.983, fig|547048.4.peg.3673, fig|502801.6.peg.938, fig|1084230.3.peg.2470, fig|992154.3.peg.3354, fig|992137.3.peg.3633, fig|992129.3.peg.3613, fig|1194970.3.peg.4403, fig|1084233.3.peg.3562, fig|992180.3.peg.3681, fig|404218.5.peg.520, fig|992185.3.peg.3376, fig|229193.14.peg.445, fig|1159617.4.peg.3543, fig|992181.3.peg.3389, fig|404215.6.peg.3070, fig|992141.3.peg.3674, fig|992149.3.peg.3652, fig|1325475.3.peg.3883, fig|992133.3.peg.3706, fig|637386.3.peg.4020, fig|992160.3.peg.3417, fig|992155.3.peg.3563, fig|992131.3.peg.3418, fig|992127.3.peg.3681, fig|992184.3.peg.3478, fig|1286089.3.peg.2479, fig|377628.10.peg.1043, fig|992148.3.peg.3713, fig|992140.3.peg.3488, fig|687916.3.peg.3066, fig|1291550.3.peg.2864, fig|545431.3.peg.4267, fig|1084227.3.peg.3766, fig|992134.3.peg.3702, fig|273123.1.peg.963, fig|992170.3.peg.3583, fig|992177.3.peg.3640, fig|1286084.3.peg.2158, fig|360102.10.peg.3523, fig|1286088.3.peg.1711, fig|649715.3.peg.3925, fig|992175.3.peg.3510, fig|992150.3.peg.3338, fig|992182.3.peg.3371, fig|992143.3.peg.3348, fig|214092.1.peg.3272, fig|992174.3.peg.3436, fig|992165.3.peg.3691, fig|360099.5.peg.2507, fig|992135.3.peg.3399, fig|992176.3.peg.3401, fig|1035377.4.peg.1916, fig|386656.9.peg.3866, fig|992183.3.peg.3620, fig|502800.3.peg.3313, fig|992162.3.peg.3509, fig|637385.3.peg.3842, fig|992179.3.peg.3398, fig|992178.3.peg.3628, fig|992168.3.peg.3329, fig|992138.3.peg.3776, fig|1084234.3.peg.3367, fig|992130.3.peg.3687, fig|992139.3.peg.3675, fig|992161.3.peg.3652, fig|992173.3.peg.3631, fig|992151.3.peg.3421, fig|992169.3.peg.3267, fig|412420.6.peg.4906, fig|992157.3.peg.3449, fig|992167.3.peg.3289, fig|373665.6.peg.1335, fig|992164.3.peg.3593, fig|992153.3.peg.3592, fig|992145.3.peg.3698 312 313 no 1919477 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1495314 Methanoculleus sp. MH98A Archaea 851218739, 635278334 KDE55749.1 WP_048113061.1 A0A063ZCH9 A0A063ZCH9_9EURY 314 317 no 1919478 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 60711 Chlorocebus sabaeus Primates UP000029965 635108736 XP_007977235.1 261 261 no 1919479 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 60711 Chlorocebus sabaeus Primates UP000029965 635108734 XP_007977234.1 489 489 yes 1919480 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2711 Citrus sinensis Plants UP000027120 641833381 KDO52395.1 216 233 no 1919481 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 695850 Saprolegnia parasitica CBS 223.65 Plants UP000030745 813141435, 641536458 KDO30347.1 XP_012198957.1 425 426 yes 1919482 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1495067 Halostagnicola sp. A56 Archaea 635282870 KDE59296.1 A0A063ZR01 A0A063ZR01_9EURY 348 349 no 1919483 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 60711 Chlorocebus sabaeus Primates UP000029965 635086807 XP_008008001.1 414 438 yes 1919484 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 60711 Chlorocebus sabaeus Primates UP000029965 635086809 XP_008008002.1 350 363 yes 1919485 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1159556 Villosiclava virens Fungi UP000027002 632918130, 781086929 KDB17569.1 A0A063CAN2 A0A063CAN2_9HYPO 460 463 yes 1919486 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1392998 Candidatus Methanoperedens nitroreducens Archaea 851158507, 630830530 KCZ72241.1 WP_048090324.1 A0A062UZ78 A0A062UZ78_9EURY 323 323 no 1919487 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8022 Oncorhynchus mykiss Vertebrates 642128534 fig|1265671.3.peg.3768, fig|1275975.3.peg.1525, fig|439851.5.peg.4588, fig|796730.3.peg.3355, fig|1235459.3.peg.1271, fig|913081.3.peg.4922, fig|913071.3.peg.4461, fig|882874.3.peg.4524, fig|997328.3.peg.3671, fig|1169660.3.peg.819, fig|882863.4.peg.2459, fig|882869.3.peg.2857, fig|871588.3.peg.1406, fig|1029985.3.peg.1853, fig|984226.3.peg.1046, fig|913241.3.peg.4554, fig|1192688.3.peg.1279, fig|454167.5.peg.76, fig|763921.3.peg.1598, fig|886722.3.peg.1161, fig|749951.3.peg.2598, fig|1182758.3.peg.2322, fig|702979.3.peg.3494, fig|882864.4.peg.119, fig|1265639.3.peg.3741, fig|1265681.3.peg.3040, fig|1029979.3.peg.2032, fig|858318.3.peg.3703, fig|1160717.4.peg.373, fig|1182168.3.peg.412, fig|882868.3.peg.102, fig|745017.4.peg.3109, fig|984229.3.peg.3729, fig|1265643.3.peg.3235, fig|1265665.3.peg.4509, fig|871590.3.peg.4104, fig|465516.5.peg.3510, fig|984233.3.peg.3555, fig|1265640.3.peg.4235, fig|1265636.3.peg.3957, fig|554290.7.peg.4298, fig|1072571.3.peg.4214, fig|984242.3.peg.3732, fig|1265664.3.peg.3919, fig|886718.3.peg.3106, fig|1265662.3.peg.4391, fig|1275976.3.peg.2092, fig|796736.3.peg.3533, fig|926034.3.peg.1830, fig|1090945.3.peg.3162, fig|1328332.3.peg.374, fig|925127.3.peg.1812, fig|891411.3.peg.3352, fig|1176487.3.peg.1938, fig|913077.3.peg.4587, fig|1265618.3.peg.3970, fig|272994.5.peg.4364, fig|1169661.3.peg.364, fig|1265646.3.peg.3050, fig|465517.10.peg.638, fig|696867.3.peg.4671, fig|1265660.3.peg.3978, fig|871591.3.peg.144, fig|1265637.3.peg.3882, fig|550538.3.peg.4372, fig|1328331.3.peg.1479, fig|926035.3.peg.1331, fig|926037.3.peg.3108, fig|1079475.3.peg.2547, fig|904139.4.peg.3137, fig|1265648.3.peg.4613, fig|1265651.3.peg.3811, fig|745018.3.peg.4509, fig|1182170.3.peg.2878, fig|984222.3.peg.2335, fig|1328329.3.peg.1113, fig|882877.3.peg.3725, fig|1265627.3.peg.4029, fig|796732.3.peg.1916, fig|886725.3.peg.2653, fig|1265624.3.peg.4653, fig|1182760.3.peg.2716, fig|887068.3.peg.1296, fig|476213.4.peg.4392, fig|1265652.3.peg.2795, fig|984216.3.peg.1199, fig|885380.3.peg.3595, fig|1265666.3.peg.3988, fig|1265673.3.peg.3804, fig|1156917.3.peg.4577, fig|749952.3.peg.1941, fig|1328334.3.peg.290, fig|1147753.3.peg.3833, fig|1265631.3.peg.3843, fig|1328328.3.peg.1061, fig|886720.3.peg.2940, fig|1265630.3.peg.4231, fig|749950.3.peg.4403, fig|1072570.3.peg.4304, fig|887069.3.peg.1182, fig|984231.3.peg.4400, fig|1265612.3.peg.3020, fig|1265623.3.peg.3320, fig|984224.3.peg.2654, fig|938147.3.peg.1213, fig|887067.3.peg.1679, fig|496064.4.peg.4132, fig|926036.3.peg.925, fig|882879.3.peg.3126, fig|1265629.3.peg.4009, fig|913075.3.peg.4662, fig|1124941.3.peg.4778, fig|1128959.3.peg.519, fig|909947.3.peg.4412, fig|454166.6.peg.4380, fig|696869.3.peg.4605, fig|1265669.3.peg.4236, fig|1265647.3.peg.3520, fig|1265668.3.peg.3800, fig|1072569.3.peg.4300, fig|882865.3.peg.1229, fig|1265625.3.peg.3878, fig|984221.3.peg.547, fig|984227.3.peg.2614, fig|925129.3.peg.3045, fig|1265677.3.peg.4174, fig|882876.3.peg.3704, fig|882860.3.peg.1843, fig|930768.3.peg.415, fig|882875.3.peg.1769, fig|887063.3.peg.1056, fig|1265613.3.peg.4103, fig|886721.3.peg.2197, fig|685040.3.peg.11, fig|984240.3.peg.4362, fig|871586.3.peg.1291, fig|1263410.4.peg.148, fig|1182759.3.peg.498, fig|1265672.3.peg.2631, fig|1265619.3.peg.2893, fig|454169.6.peg.4529, fig|925126.3.peg.4413, fig|749947.3.peg.1558, fig|454165.5.peg.2174, fig|887070.3.peg.1052, fig|885385.3.peg.1063, fig|886723.3.peg.3653, fig|1265628.3.peg.3332, fig|859199.4.peg.3736, fig|913073.3.peg.4506, fig|885384.3.peg.1005, fig|984223.3.peg.2178, fig|871589.3.peg.433, fig|1265678.3.peg.3284, fig|910417.3.peg.3150, fig|1132507.4.peg.4472, fig|858306.3.peg.3660, fig|984225.3.peg.4671, fig|910415.3.peg.1169, fig|1147754.3.peg.2519, fig|858308.3.peg.2781, fig|763919.3.peg.1805, fig|745020.4.peg.4527, fig|941188.3.peg.4199, fig|858311.3.peg.2339, fig|858310.3.peg.841, fig|909945.3.peg.4530, fig|887065.3.peg.1371, fig|891413.3.peg.3175, fig|997329.3.peg.1520, fig|687915.3.peg.408, fig|1265620.3.peg.3936, fig|858314.3.peg.2947, fig|1176488.3.peg.3461, fig|1265633.3.peg.4008, fig|1116476.3.peg.630, fig|1265674.3.peg.1852, fig|766761.3.peg.1613, fig|439843.6.peg.4458, fig|1072572.3.peg.4273, fig|1265653.3.peg.3105, fig|910414.3.peg.2150, fig|796733.3.peg.2763, fig|930769.3.peg.330, fig|910419.3.peg.1418, fig|984234.3.peg.4527, fig|749949.3.peg.4557, fig|984228.3.peg.3149, fig|766762.3.peg.4354, fig|1265657.3.peg.3799, fig|871593.3.peg.3641, fig|913242.3.peg.5174, fig|882878.3.peg.1539, fig|858313.3.peg.2206, fig|1265655.3.peg.3801, fig|886715.3.peg.1007, fig|702978.3.peg.4433, fig|1265661.3.peg.3163, fig|885381.3.peg.3743, fig|1128963.3.peg.2768, fig|1265644.3.peg.3887, fig|1265621.3.peg.4145, fig|1192853.3.peg.2773, fig|886724.3.peg.1560, fig|984219.3.peg.2516, fig|882873.3.peg.696, fig|209261.1.peg.3890, fig|925131.3.peg.1140, fig|913078.3.peg.4398, fig|1116477.3.peg.1055, fig|1124937.3.peg.3898, fig|789332.3.peg.3976, fig|858317.4.peg.1616, fig|1265638.3.peg.4255, fig|596155.6.peg.4387, fig|1081093.3.peg.4356, fig|749953.3.peg.2627, fig|1265663.3.peg.3970, fig|796735.3.peg.130, fig|1265635.3.peg.2315, fig|1179780.3.peg.1280, fig|1265611.3.peg.4029, fig|885386.3.peg.3754, fig|702976.3.peg.3576, fig|984215.3.peg.1577, fig|984241.3.peg.3546, fig|696870.3.peg.213, fig|1265667.3.peg.4000, fig|696868.4.peg.2412, fig|871592.3.peg.3940, fig|763920.3.peg.1019, fig|1262654.4.peg.285, fig|984230.3.peg.2973, fig|925133.3.peg.467, fig|1212554.4.peg.1964, fig|1265645.3.peg.3492, fig|1265675.3.peg.3995, fig|749948.3.peg.3774, fig|885383.3.peg.3263, fig|763922.3.peg.1114, fig|887064.3.peg.3666, fig|1029986.3.peg.4747, fig|886717.3.peg.3814, fig|796731.3.peg.1871, fig|925130.3.peg.2351, fig|1265676.3.peg.3610, fig|696866.4.peg.2634, fig|925128.3.peg.649, fig|913083.3.peg.4762, fig|910416.3.peg.1258, fig|910413.3.peg.1269, fig|1265670.3.peg.3842, fig|891414.3.peg.1291, fig|984220.3.peg.4123, fig|1265617.3.peg.2711, fig|984217.3.peg.580, fig|858305.3.peg.4297, fig|910418.3.peg.1066, fig|1182164.3.peg.3074, fig|984214.3.peg.1560, fig|913072.3.peg.4501, fig|871587.3.peg.3390, fig|1212561.4.peg.3153, fig|1265615.3.peg.3532, fig|885387.3.peg.3768, fig|1265632.3.peg.3938, fig|1265634.3.peg.1598, fig|882867.3.peg.3064, fig|887066.3.peg.834, fig|550537.3.peg.4296, fig|1265622.3.peg.4117, fig|1267753.3.peg.2631, fig|1212559.4.peg.610, fig|1265680.3.peg.3864, fig|745021.4.peg.1229, fig|497974.4.peg.3536, fig|858315.3.peg.3187, fig|984218.3.peg.1728, fig|1265650.3.peg.3827, fig|745022.3.peg.1035, fig|745019.4.peg.3548, fig|925132.3.peg.3469, fig|1265642.3.peg.3966, fig|984232.3.peg.3517, fig|321314.4.peg.4064, fig|1079476.3.peg.3736, fig|886727.3.peg.3592, fig|913084.3.peg.4605, fig|1265626.3.peg.3837, fig|984212.3.peg.4368, fig|687860.3.peg.2447, fig|882862.3.peg.2050, fig|1262652.4.peg.475, fig|885382.3.peg.3165, fig|1182167.3.peg.3595, fig|882872.3.peg.1011, fig|1182757.3.peg.2349, fig|859198.4.peg.3772, fig|1265659.3.peg.4145, fig|1328333.3.peg.1237, fig|1265641.3.peg.3699, fig|913080.3.peg.4497, fig|1328326.3.peg.179, fig|220341.1.peg.3958, fig|1265616.3.peg.3728, fig|454164.6.peg.3257, fig|886719.3.peg.3712, fig|1212557.4.peg.635, fig|1265614.3.peg.3946, fig|1182761.3.peg.2868, fig|984213.3.peg.656, fig|696864.3.peg.4411, fig|886726.3.peg.668, fig|1072568.3.peg.4269, fig|891412.3.peg.1627, fig|796737.3.peg.3371, fig|886728.3.peg.3885, fig|886716.3.peg.904, fig|858307.3.peg.77, fig|1265679.3.peg.3761, fig|913086.3.peg.4710, fig|295319.15.peg.4333, fig|745015.3.peg.1588, fig|423368.6.peg.4605, fig|696865.3.peg.1996, fig|882866.3.peg.4318 496 499 yes 1919488 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1037660 Tilletiaria anomala UBC 951 Fungi UP000027361 639565873 KDN43420.1 541 541 yes 1919489 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 65357 Albugo candida Plants UP000053237 635365335 724 724 yes 1919490 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1291522 Helicosporidium sp. ATCC 50920 Plants UP000026042 633906479 KDD73235.1 341 342 no 1919491 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1287689 Rhizoctonia solani AG-8 WAC10335 Fungi UP000027042 639560371 KDN38165.1 fig|3702.11.peg.51 493 503 no 1919492 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1287689 Rhizoctonia solani AG-8 WAC10335 Fungi UP000027042 639560372 KDN38166.1 fig|3702.11.peg.52 193 207 no 1919493 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9478 Tarsius syrichta Primates 640810068 XP_008061609.1 fig|381754.5.peg.964 436 442 yes 1919494 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1291522 Helicosporidium sp. ATCC 50920 Plants UP000026042 633908735 KDD74264.1 236 236 no 1919495 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9478 Tarsius syrichta Primates 640800693 XP_008056604.1 fig|484021.4.peg.4321, fig|640131.3.peg.483, fig|1284831.3.peg.349, fig|1094167.3.peg.709, fig|1284821.3.peg.955, fig|1284810.3.peg.2511, fig|1128954.3.peg.1214, fig|1284788.3.peg.1152, fig|1304920.3.peg.2072, fig|1284816.3.peg.4540, fig|1304923.3.peg.1901, fig|1128951.3.peg.927, fig|1128953.3.peg.2315, fig|272620.3.peg.3659, fig|1279040.3.peg.651, fig|1284790.3.peg.4633, fig|1263871.3.peg.4100, fig|1037908.3.peg.1181, fig|1168062.3.peg.2617, fig|1316939.3.peg.1514, fig|1094170.3.peg.901, fig|1193292.6.peg.498, fig|1284830.3.peg.2656, fig|1284828.3.peg.5021, fig|1087443.3.peg.2950, fig|1168063.3.peg.1561, fig|1168064.3.peg.949, fig|1284801.3.peg.1174, fig|1087440.3.peg.590, fig|1203545.3.peg.4232, fig|1284829.3.peg.2598, fig|1177153.3.peg.4561, fig|1267512.3.peg.1390, fig|1203544.3.peg.537, fig|1284812.3.peg.2028, fig|1226115.3.peg.723, fig|1304922.3.peg.597, fig|1236101.6.peg.5335, fig|1087441.3.peg.857, fig|1094168.3.peg.851, fig|1267897.3.peg.2013, fig|1284796.3.peg.4605, fig|665944.3.peg.4545, fig|1294269.3.peg.2305, fig|1284817.3.peg.2346, fig|469608.3.peg.2877, fig|1185419.3.peg.2335, fig|1087444.3.peg.224, fig|1284834.3.peg.2772, fig|1226680.3.peg.4346, fig|1284822.3.peg.1631, fig|1236102.6.peg.1545, fig|667127.3.peg.3001, fig|1276652.3.peg.981, fig|1094169.3.peg.913, fig|1284824.3.peg.758, fig|1125630.4.peg.4643, fig|1128952.3.peg.425, fig|1162297.3.peg.3199, fig|1284814.3.peg.3624, fig|1185420.3.peg.319, fig|1284820.3.peg.4872, fig|1182695.3.peg.4448, fig|1284787.3.peg.4883, fig|1128946.3.peg.270, fig|1128948.3.peg.2374, fig|1037890.3.peg.1601, fig|1185418.3.peg.1874, fig|1284827.3.peg.582, fig|1203547.3.peg.3885, fig|1212766.3.peg.1079, fig|1284811.3.peg.4829, fig|1284815.3.peg.1821, fig|1094171.3.peg.2707, fig|1284823.3.peg.295, fig|1087445.3.peg.564, fig|1049565.4.peg.4246, fig|749535.4.peg.436, fig|1304924.3.peg.3978, fig|1128950.3.peg.411, fig|1284832.3.peg.991, fig|1284813.3.peg.2886, fig|507522.6.peg.720, fig|1284826.3.peg.2990, fig|1316938.3.peg.814, fig|1284825.3.peg.2289, fig|1284819.3.peg.1448, fig|1074486.3.peg.2700 261 261 no 1919496 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9478 Tarsius syrichta Primates 640800691 XP_008056603.1 fig|1284834.3.peg.2770, fig|1185420.3.peg.317, fig|1087444.3.peg.222, fig|1094169.3.peg.911, fig|484021.4.peg.4319, fig|1094171.3.peg.2705, fig|1284830.3.peg.2658, fig|1284815.3.peg.1823, fig|1128946.3.peg.268, fig|1284831.3.peg.347, fig|1128954.3.peg.1212, fig|1284823.3.peg.293, fig|1226680.3.peg.4344, fig|1284822.3.peg.1629, fig|1284816.3.peg.4538, fig|1284821.3.peg.953, fig|1049565.4.peg.4244, fig|1284824.3.peg.756, fig|1284788.3.peg.1150, fig|1168063.3.peg.1563, fig|1284801.3.peg.1172, fig|1087445.3.peg.562, fig|1128953.3.peg.2317, fig|1074486.3.peg.2698, fig|749535.4.peg.438, fig|1284828.3.peg.5019, fig|1203545.3.peg.4230, fig|1128951.3.peg.925, fig|1128950.3.peg.413, fig|1284826.3.peg.2988, fig|1162297.3.peg.3197, fig|1284814.3.peg.3622, fig|1284813.3.peg.2888, fig|1128952.3.peg.427, fig|1263871.3.peg.4098, fig|1294269.3.peg.2303, fig|272620.3.peg.3657, fig|1284832.3.peg.993, fig|1284790.3.peg.4631, fig|1125630.4.peg.4641, fig|1212766.3.peg.1081, fig|1304922.3.peg.595, fig|1304924.3.peg.3976, fig|1316939.3.peg.1516, fig|1226115.3.peg.725, fig|1284829.3.peg.2596, fig|1168062.3.peg.2619, fig|1284811.3.peg.4827, fig|1284820.3.peg.4870, fig|1168064.3.peg.947, fig|1236101.6.peg.5333, fig|1177153.3.peg.4559, fig|1276652.3.peg.979, fig|1087443.3.peg.2948, fig|1037908.3.peg.1183, fig|1304920.3.peg.2070, fig|1267897.3.peg.2015, fig|1094168.3.peg.849, fig|1267512.3.peg.1392, fig|1236102.6.peg.1543, fig|1284787.3.peg.4881, fig|1203544.3.peg.539, fig|1279040.3.peg.649, fig|1193292.6.peg.500, fig|1316938.3.peg.812, fig|1284796.3.peg.4603, fig|1087440.3.peg.588, fig|1037890.3.peg.1603, fig|1128948.3.peg.2376, fig|665944.3.peg.4547, fig|1284810.3.peg.2509, fig|1203547.3.peg.3883, fig|1185418.3.peg.1872, fig|1304923.3.peg.1899, fig|1094167.3.peg.711, fig|1284825.3.peg.2287, fig|1284819.3.peg.1446, fig|1284812.3.peg.2030, fig|1284817.3.peg.2344, fig|1162296.3.peg.4178, fig|1185419.3.peg.2333, fig|1094170.3.peg.899, fig|1284827.3.peg.584, fig|667127.3.peg.2999, fig|1087441.3.peg.855 487 487 yes 1919497 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1288291 Anncaliia algerae PRA339 Fungi UP000030655 630921255 KCZ81810.1 358 363 yes 1919498 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 691883 Fonticula alba Invertebrates UP000030693 694531279, 627949134 KCV70998.1 XP_009494121.1 712 716 no 1919499 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2711 Citrus sinensis Plants UP000027120 641833377 KDO52391.1 fig|502801.6.peg.2545, fig|1084228.3.peg.4208, fig|637382.3.peg.1958, fig|992131.3.peg.2467, fig|637385.3.peg.1927, fig|992151.3.peg.2467, fig|360102.10.peg.2198, fig|992175.3.peg.2556, fig|992130.3.peg.2737, fig|992162.3.peg.2561, fig|992178.3.peg.2676, fig|992179.3.peg.2448, fig|992158.3.peg.2473, fig|992154.3.peg.2414, fig|1286088.3.peg.1970, fig|992137.3.peg.2694, fig|992128.3.peg.2625, fig|992159.3.peg.2341, fig|992164.3.peg.2651, fig|992134.3.peg.2746, fig|992166.3.peg.2328, fig|1286084.3.peg.1440, fig|273123.1.peg.2370, fig|992132.3.peg.2729, fig|992153.3.peg.2651, fig|547048.4.peg.2009, fig|992136.3.peg.2521, fig|992160.3.peg.2475, fig|1286085.3.peg.3912, fig|992156.3.peg.2283, fig|992155.3.peg.2632, fig|1084226.3.peg.1847, fig|992176.3.peg.2446, fig|992185.3.peg.2452, fig|547046.3.peg.98, fig|992180.3.peg.2740, fig|992139.3.peg.2723, fig|1286087.3.peg.702, fig|992140.3.peg.2573, fig|992169.3.peg.2335, fig|992148.3.peg.2762, fig|404214.5.peg.2562, fig|214092.1.peg.2409, fig|992163.3.peg.2716, fig|992172.3.peg.2517, fig|992152.3.peg.2757, fig|545431.3.peg.2849, fig|992138.3.peg.2797, fig|1084229.3.peg.3645, fig|547047.3.peg.2864, fig|1325475.3.peg.2543, fig|1084230.3.peg.2479, fig|404216.5.peg.2189, fig|687916.3.peg.4338, fig|992129.3.peg.2666, fig|373665.6.peg.3357, fig|992127.3.peg.2727, fig|992142.3.peg.2554, fig|1324587.3.peg.2207, fig|992149.3.peg.2705, fig|1035377.4.peg.2898, fig|992182.3.peg.2430, fig|992157.3.peg.2488, fig|1159617.4.peg.2550, fig|377628.10.peg.2200, fig|1084234.3.peg.430, fig|1286086.3.peg.1840, fig|992161.3.peg.2700, fig|992173.3.peg.2694, fig|1286089.3.peg.701, fig|404217.5.peg.3959, fig|992177.3.peg.2691, fig|992147.3.peg.2662, fig|992141.3.peg.2724, fig|1084233.3.peg.4257, fig|649715.3.peg.176, fig|349747.3.peg.752, fig|1291550.3.peg.1993, fig|992171.3.peg.2634, fig|992174.3.peg.2489, fig|992183.3.peg.2674, fig|349746.3.peg.2056, fig|1084227.3.peg.1536, fig|992165.3.peg.2740, fig|187410.1.peg.1943, fig|1194970.3.peg.3040, fig|229193.1.peg.2072, fig|992181.3.peg.2442, fig|637386.3.peg.2204, fig|1084232.3.peg.3292, fig|992135.3.peg.2454, fig|992184.3.peg.2545, fig|992133.3.peg.2734, fig|360099.5.peg.3034, fig|386656.4.peg.926, fig|404215.6.peg.700, fig|992144.3.peg.2521, fig|992170.3.peg.2614, fig|992150.3.peg.2398, fig|404218.5.peg.2927, fig|992146.3.peg.2639, fig|375450.5.peg.2419, fig|412420.6.peg.1268, fig|992145.3.peg.2742, fig|502800.3.peg.1868, fig|992168.3.peg.2384, fig|1324608.3.peg.3009, fig|992167.3.peg.2339, fig|992143.3.peg.2411, fig|1084231.3.peg.2421 407 409 yes 1919500 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2711 Citrus sinensis Plants UP000027120 641833380, 641833379, 641833378 KDO52394.1, KDO52393.1, KDO52392.1 fig|992144.3.peg.2524, fig|502801.6.peg.2546, fig|502801.6.peg.2547, fig|637382.3.peg.1956, fig|637382.3.peg.1957, fig|637382.3.peg.1955, fig|502801.6.peg.2548, fig|377628.10.peg.2202, fig|992134.3.peg.2748, fig|992143.3.peg.2412, fig|377628.10.peg.2203, fig|992151.3.peg.2469, fig|992151.3.peg.2468, fig|360102.10.peg.2199, fig|992140.3.peg.2575, fig|992140.3.peg.2574, fig|992131.3.peg.2469, fig|992140.3.peg.2576, fig|992175.3.peg.2557, fig|992138.3.peg.2800, fig|992174.3.peg.2490, fig|1324608.3.peg.3011, fig|992156.3.peg.2284, fig|1324608.3.peg.3012, fig|1084226.3.peg.1850, fig|1084228.3.peg.4209, fig|992141.3.peg.2727, fig|992141.3.peg.2726, fig|992175.3.peg.2559, fig|992175.3.peg.2558, fig|992167.3.peg.2341, fig|1286086.3.peg.1841, fig|992167.3.peg.2342, fig|992154.3.peg.2417, fig|992154.3.peg.2416, fig|992154.3.peg.2415, fig|1286087.3.peg.699, fig|1286089.3.peg.702, fig|992166.3.peg.2331, fig|992166.3.peg.2330, fig|992137.3.peg.2696, fig|992137.3.peg.2697, fig|992137.3.peg.2695, fig|992128.3.peg.2627, fig|1084226.3.peg.1849, fig|992164.3.peg.2654, fig|992134.3.peg.2749, fig|992164.3.peg.2653, fig|992159.3.peg.2342, fig|992159.3.peg.2343, fig|992173.3.peg.2696, fig|547046.3.peg.99, fig|1084228.3.peg.4211, fig|1084228.3.peg.4210, fig|992128.3.peg.2628, fig|992131.3.peg.2470, fig|1286084.3.peg.1442, fig|1286084.3.peg.1441, fig|229193.1.peg.2074, fig|992156.3.peg.2285, fig|992153.3.peg.2654, fig|229193.1.peg.2073, fig|273123.1.peg.2371, fig|404214.5.peg.2563, fig|992152.3.peg.2758, fig|992151.3.peg.2470, fig|992153.3.peg.2653, fig|992136.3.peg.2523, fig|992130.3.peg.2740, fig|992156.3.peg.2286, fig|404216.5.peg.2190, fig|1286085.3.peg.3910, fig|1286085.3.peg.3911, fig|992162.3.peg.2564, fig|992136.3.peg.2524, fig|992161.3.peg.2701, fig|992155.3.peg.2633, fig|992155.3.peg.2634, fig|992155.3.peg.2635, fig|992160.3.peg.2478, fig|214092.1.peg.2412, fig|992176.3.peg.2447, fig|992142.3.peg.2555, fig|992172.3.peg.2518, fig|992131.3.peg.2468, fig|992172.3.peg.2519, fig|545431.3.peg.2851, fig|992176.3.peg.2449, fig|992179.3.peg.2450, fig|992179.3.peg.2451, fig|187410.1.peg.1942, fig|992159.3.peg.2344, fig|214092.1.peg.2411, fig|992139.3.peg.2726, fig|404217.5.peg.3958, fig|992180.3.peg.2742, fig|992180.3.peg.2743, fig|214092.1.peg.2410, fig|992169.3.peg.2338, fig|1286087.3.peg.700, fig|992132.3.peg.2732, fig|992132.3.peg.2730, fig|992132.3.peg.2731, fig|992149.3.peg.2708, fig|992169.3.peg.2337, fig|404214.5.peg.2564, fig|404214.5.peg.2565, fig|992148.3.peg.2763, fig|992148.3.peg.2764, fig|992148.3.peg.2765, fig|360102.10.peg.2201, fig|360102.10.peg.2200, fig|547048.4.peg.2012, fig|992147.3.peg.2664, fig|1286085.3.peg.3909, fig|547048.4.peg.2011, fig|1324587.3.peg.2210, fig|637386.3.peg.2201, fig|1084233.3.peg.4254, fig|992163.3.peg.2717, fig|1194970.3.peg.3041, fig|637385.3.peg.1928, fig|992138.3.peg.2798, fig|992138.3.peg.2799, fig|404216.5.peg.2192, fig|404216.5.peg.2191, fig|992152.3.peg.2759, fig|547047.3.peg.2865, fig|992163.3.peg.2718, fig|992163.3.peg.2719, fig|1084229.3.peg.3646, fig|1084229.3.peg.3647, fig|1084230.3.peg.2476, fig|1084230.3.peg.2477, fig|1291550.3.peg.1996, fig|547047.3.peg.2867, fig|547047.3.peg.2866, fig|1325475.3.peg.2541, fig|1325475.3.peg.2540, fig|1084229.3.peg.3648, fig|349747.3.peg.753, fig|1324608.3.peg.3010, fig|992127.3.peg.2729, fig|992127.3.peg.2728, fig|992129.3.peg.2667, fig|992129.3.peg.2668, fig|992129.3.peg.2669, fig|637385.3.peg.1930, fig|687916.3.peg.4337, fig|687916.3.peg.4336, fig|687916.3.peg.4335, fig|992142.3.peg.2556, fig|992179.3.peg.2449, fig|1324587.3.peg.2209, fig|1324587.3.peg.2208, fig|992143.3.peg.2414, fig|1325475.3.peg.2542, fig|992176.3.peg.2448, fig|992139.3.peg.2724, fig|992169.3.peg.2336, fig|992185.3.peg.2454, fig|545431.3.peg.2850, fig|992149.3.peg.2707, fig|992172.3.peg.2520, fig|992182.3.peg.2432, fig|992182.3.peg.2433, fig|992182.3.peg.2431, fig|992157.3.peg.2489, fig|992174.3.peg.2491, fig|1035377.4.peg.2896, fig|1035377.4.peg.2895, fig|992174.3.peg.2492, fig|1084234.3.peg.431, fig|377628.10.peg.2201, fig|1084234.3.peg.433, fig|1084234.3.peg.432, fig|375450.5.peg.2417, fig|992185.3.peg.2453, fig|992160.3.peg.2476, fig|992161.3.peg.2703, fig|992161.3.peg.2702, fig|1286086.3.peg.1843, fig|1286086.3.peg.1842, fig|273123.1.peg.2372, fig|273123.1.peg.2373, fig|547046.3.peg.100, fig|547046.3.peg.101, fig|373665.6.peg.3354, fig|1286089.3.peg.703, fig|992135.3.peg.2455, fig|1286089.3.peg.704, fig|992158.3.peg.2474, fig|992144.3.peg.2523, fig|404217.5.peg.3957, fig|404217.5.peg.3956, fig|992147.3.peg.2663, fig|1084233.3.peg.4255, fig|992147.3.peg.2665, fig|992130.3.peg.2738, fig|992158.3.peg.2475, fig|1291550.3.peg.1995, fig|1291550.3.peg.1994, fig|349747.3.peg.755, fig|349747.3.peg.754, fig|992136.3.peg.2522, fig|992171.3.peg.2636, fig|992171.3.peg.2637, fig|992171.3.peg.2635, fig|992160.3.peg.2477, fig|1159617.4.peg.2552, fig|992157.3.peg.2490, fig|992158.3.peg.2476, fig|992142.3.peg.2557, fig|992139.3.peg.2725, fig|992183.3.peg.2677, fig|992183.3.peg.2676, fig|992183.3.peg.2675, fig|992157.3.peg.2491, fig|649715.3.peg.179, fig|992130.3.peg.2739, fig|1286087.3.peg.701, fig|649715.3.peg.178, fig|349746.3.peg.2054, fig|349746.3.peg.2055, fig|992185.3.peg.2455, fig|373665.6.peg.3355, fig|992141.3.peg.2725, fig|992144.3.peg.2522, fig|1084232.3.peg.3289, fig|1159617.4.peg.2553, fig|1084227.3.peg.1533, fig|1084227.3.peg.1534, fig|1084227.3.peg.1535, fig|992165.3.peg.2743, fig|992165.3.peg.2742, fig|992165.3.peg.2741, fig|992180.3.peg.2741, fig|992178.3.peg.2677, fig|1194970.3.peg.3043, fig|1194970.3.peg.3042, fig|187410.1.peg.1941, fig|187410.1.peg.1940, fig|992127.3.peg.2730, fig|373665.6.peg.3356, fig|992178.3.peg.2679, fig|992178.3.peg.2678, fig|637386.3.peg.2203, fig|637386.3.peg.2202, fig|992181.3.peg.2444, fig|992181.3.peg.2445, fig|992173.3.peg.2697, fig|992181.3.peg.2443, fig|375450.5.peg.2418, fig|992167.3.peg.2340, fig|229193.1.peg.2075, fig|992152.3.peg.2760, fig|992135.3.peg.2456, fig|992135.3.peg.2457, fig|1084232.3.peg.3291, fig|1084232.3.peg.3290, fig|649715.3.peg.177, fig|992184.3.peg.2546, fig|992184.3.peg.2547, fig|992184.3.peg.2548, fig|992133.3.peg.2737, fig|992133.3.peg.2736, fig|992177.3.peg.2694, fig|992168.3.peg.2385, fig|992133.3.peg.2735, fig|992128.3.peg.2626, fig|360099.5.peg.3031, fig|992177.3.peg.2692, fig|360099.5.peg.3033, fig|360099.5.peg.3032, fig|992146.3.peg.2641, fig|992146.3.peg.2640, fig|992177.3.peg.2693, fig|386656.4.peg.925, fig|386656.4.peg.924, fig|386656.4.peg.923, fig|404215.6.peg.703, fig|404215.6.peg.702, fig|992170.3.peg.2617, fig|992170.3.peg.2616, fig|992170.3.peg.2615, fig|992173.3.peg.2695, fig|992150.3.peg.2399, fig|404215.6.peg.701, fig|992149.3.peg.2706, fig|404218.5.peg.2924, fig|404218.5.peg.2925, fig|404218.5.peg.2926, fig|992146.3.peg.2642, fig|992153.3.peg.2652, fig|992134.3.peg.2747, fig|1286088.3.peg.1969, fig|637385.3.peg.1929, fig|992162.3.peg.2562, fig|547048.4.peg.2010, fig|992166.3.peg.2329, fig|1084233.3.peg.4256, fig|1084231.3.peg.2422, fig|412420.6.peg.1267, fig|412420.6.peg.1266, fig|412420.6.peg.1265, fig|375450.5.peg.2416, fig|992145.3.peg.2745, fig|992145.3.peg.2744, fig|1084226.3.peg.1848, fig|992164.3.peg.2652, fig|1286084.3.peg.1443, fig|1286088.3.peg.1967, fig|992145.3.peg.2743, fig|992162.3.peg.2563, fig|1035377.4.peg.2897, fig|1084230.3.peg.2478, fig|502800.3.peg.1866, fig|502800.3.peg.1867, fig|502800.3.peg.1865, fig|1159617.4.peg.2551, fig|1286088.3.peg.1968, fig|992168.3.peg.2386, fig|992150.3.peg.2400, fig|992150.3.peg.2401, fig|1084231.3.peg.2424, fig|992168.3.peg.2387, fig|992143.3.peg.2413, fig|1084231.3.peg.2423 339 341 yes 1919501 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7868 Callorhinchus milii Vertebrates 632963702 XP_007898034.1 415 417 yes 1919502 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28377 Anolis carolinensis Vertebrates UP000001646 UP000001646 637375364 XP_003230257.2 fig|224911.1.peg.7771 402 402 yes 1919503 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9258 Ornithorhynchus anatinus Mammals UP000002279 UP000002279 620983210 XP_007657900.1 102 118 no 1919504 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1173701 Colletotrichum sublineola Fungi UP000027238 640928759 KDN72159.1 443 449 yes 1919505 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1291522 Helicosporidium sp. ATCC 50920 Plants UP000026042 633907136 KDD73510.1 156 167 no 1919506 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 71139 Eucalyptus grandis Plants UP000030711 702389774, 702389770, 702389767, 702389764, 629097291 KCW63056.1 XP_010065526.1, XP_010065525.1, XP_010065524.1, XP_010065523.1 446 458 yes 1919507 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1240240 Anncaliia algerae PRA109 Fungi UP000054343 630912425 KCZ76981.1 206 208 no 1919508 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1230840 Orycteropus afer afer Mammals 634882348 XP_007951259.1 489 489 yes 1919509 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10029 Cricetulus griseus Rodents UP000030759 625260059 XP_007621453.1 413 438 yes 1919510 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 65357 Albugo candida Plants UP000053237 635370387 502 958 yes 1919511 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7029 Acyrthosiphon pisum Invertebrates UP000007819 641677292 XP_008187718.1 fig|860575.3.peg.1587, fig|43989.4.peg.2832 411 413 yes 1919512 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 71139 Eucalyptus grandis Plants UP000030711 702236377, 629123196 KCW87621.1 XP_010054686.1 503 505 yes 1919513 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28377 Anolis carolinensis Vertebrates UP000001646 UP000001646 637294439 XP_008107708.1 fig|190486.1.peg.1169 481 481 yes 1919514 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1230840 Orycteropus afer afer Mammals 634839066 XP_007935765.1 354 392 yes 1919515 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 695850 Saprolegnia parasitica CBS 223.65 Plants UP000030745 813135671, 641537002 KDO30873.1 XP_012198568.1 fig|449447.3.peg.2753 495 500 yes 1919516 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1037660 Tilletiaria anomala UBC 951 Fungi UP000027361 639575248 KDN52597.1 fig|3702.11.peg.7451 592 593 no 1919517 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 683840 Microbotryum violaceum p1A1 Lamole Fungi UP000017200 634347689 KDE03185.1 U5HGV6 U5HGV6_USTV1 570 576 yes 1919518 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7868 Callorhinchus milii Vertebrates 632975720 XP_007904383.1 364 372 yes 1919519 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29078 Eptesicus fuscus Mammals 641713662 XP_008146111.1 fig|334390.3.peg.306 404 438 yes 1919520 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9258 Ornithorhynchus anatinus Mammals UP000002279 UP000002279 620966832 XP_007656565.1 282 569 no 1919521 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1159556 Villosiclava virens Fungi UP000027002 632914539, 781081599 KDB14181.1 A0A063BVX2 A0A063BVX2_9HYPO 551 551 yes 1919522 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7868 Callorhinchus milii Vertebrates 632963700, 632963698, 632963696, 632963694, 398667692 AFO95322.1 XP_007898033.1, XP_007898032.1, XP_007898031.1, XP_007898030.1 501 501 yes 1919523 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1240240 Anncaliia algerae PRA109 Fungi UP000054343 630905972 KCZ75191.1 151 154 no 1919524 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 7868 Callorhinchus milii Vertebrates 632975718 XP_007904382.1 455 465 yes 1919525 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5854 Plasmodium reichenowi Invertebrates UP000027581 832039870, 641578568 XP_012765202.1 484 489 yes 1919526 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28377 Anolis carolinensis Vertebrates UP000001646 UP000001646 637294443 XP_008107709.1 fig|1137651.4.peg.1326, fig|1156940.3.peg.4094, fig|190486.1.peg.1173, fig|1304892.4.peg.1299, fig|1150615.3.peg.1258, fig|1118965.3.peg.3726 411 411 yes 1919527 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 10029 Cricetulus griseus Rodents UP000030759 625260061, 625210244 XP_007621454.1, XP_007646030.1 344 363 yes 1919528 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1173701 Colletotrichum sublineola Fungi UP000027238 640914838 KDN59799.1 fig|1169393.3.peg.2122, fig|749528.3.peg.893, fig|1182736.3.peg.2198, fig|1169387.3.peg.2116, fig|1182692.3.peg.2631, fig|1169360.3.peg.2164, fig|1181747.3.peg.2970, fig|749550.3.peg.4149, fig|1206108.3.peg.3701, fig|1308981.3.peg.2444, fig|1169335.3.peg.2808, fig|749541.3.peg.4830, fig|1169364.3.peg.2083, fig|1182667.3.peg.2681, fig|1182666.3.peg.2667, fig|655817.3.peg.2371, fig|1162297.3.peg.4435, fig|714962.3.peg.2211, fig|1181760.3.peg.3319, fig|1182665.3.peg.2748, fig|199310.1.peg.2391, fig|749546.3.peg.631, fig|1182691.3.peg.2345, fig|1284812.3.peg.1234, fig|316435.3.peg.1334, fig|1258567.3.peg.3570, fig|1181751.3.peg.2060, fig|1181769.3.peg.2683, fig|1182662.3.peg.2840, fig|1182693.3.peg.1962, fig|1181766.3.peg.1869, fig|1181761.3.peg.2230, fig|656390.3.peg.2549, fig|1169356.3.peg.2788, fig|1182696.3.peg.2296, fig|1169381.3.peg.2243, fig|1169395.3.peg.2073, fig|1169390.3.peg.2100, fig|1182712.3.peg.4283, fig|1169400.3.peg.2234, fig|869685.3.peg.3061, fig|1181729.3.peg.1051, fig|1182672.3.peg.2012, fig|1169403.3.peg.2041, fig|1258580.3.peg.3857, fig|753642.3.peg.2310, fig|525281.3.peg.491, fig|749536.3.peg.2937, fig|1182660.3.peg.2674, fig|1181741.3.peg.2282, fig|1169398.3.peg.1907, fig|1181772.3.peg.2182, fig|1169341.3.peg.1812, fig|1181755.3.peg.4826, fig|1163386.3.peg.1928, fig|469598.5.peg.3230, fig|1182670.3.peg.2830, fig|1169385.3.peg.2053, fig|1182664.3.peg.3569, fig|1203544.3.peg.1835, fig|749530.3.peg.2247, fig|869729.3.peg.1512, fig|290338.6.peg.750, fig|1181770.3.peg.2164, fig|1181735.3.peg.2339, fig|1182674.3.peg.2912, fig|1181734.3.peg.2446, fig|1182721.3.peg.2586, fig|1181752.3.peg.2310, fig|1182679.3.peg.2180, fig|1181775.3.peg.674, fig|1169404.3.peg.2181, fig|1181737.3.peg.2683, fig|1181728.3.peg.2094, fig|935296.3.peg.597, fig|1169374.3.peg.2005, fig|1169399.3.peg.2147, fig|1181753.3.peg.2821, fig|1169370.3.peg.1952, fig|340197.3.peg.6, fig|885276.3.peg.2173, fig|1169366.3.peg.1863, fig|362663.8.peg.1991, fig|885275.3.peg.2171, fig|1322345.3.peg.2556, fig|1169386.3.peg.2096, fig|1181764.3.peg.2890, fig|1169334.3.peg.1895, fig|1181776.3.peg.2326, fig|656398.3.peg.737, fig|1182709.3.peg.2982, fig|1308983.3.peg.542, fig|1169371.3.peg.2075, fig|1169328.3.peg.2196, fig|364106.7.peg.2239, fig|1181733.3.peg.2543, fig|1169384.3.peg.2162, fig|1169372.3.peg.2038 530 530 yes 1919529 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 691883 Fonticula alba Invertebrates UP000030693 694532888, 627949600 KCV71464.1 XP_009494587.1 440 445 yes 2196738 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1080712 Methanomassiliicoccus luminyensis Archaea 648287714 WP_026068863.1 339 348 no 2196739 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 930990 Botryobasidium botryosum FD-172 SS1 Fungi UP000027195 646299552 KDQ20706.1 504 509 no 2196740 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 933084 Jaapia argillacea MUCL 33604 Fungi UP000027265 646389145 KDQ53934.1 529 529 yes 2196741 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5866 Babesia bigemina Invertebrates UP000033188 833490219, 656186502 XP_012769086.1 469 475 yes 2196742 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 180498 Jatropha curcas Plants UP000027138 802608155, 643728266 KDP36406.1 XP_012074066.1 451 455 yes 2196743 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 102107 Prunus mume Plants 645234417 XP_008223801.1 504 504 yes 2196744 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5866 Babesia bigemina Invertebrates UP000033188 833482657, 656183673 XP_012766700.1 429 429 no 2196745 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182545 Exophiala aquamarina CBS 119918 Fungi UP000027920 656912700 KEF58282.1 437 449 yes 2196746 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 144197 Stegastes partitus Vertebrates 657576378 XP_008291969.1 292 302 no 2196747 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1137138 Pleurotus ostreatus PC15 Fungi UP000027073 646306286 KDQ27431.1 488 490 yes 2196748 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9986 Oryctolagus cuniculus Mammals UP000001811 655869334 XP_008269143.1 422 438 yes 2196749 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1182545 Exophiala aquamarina CBS 119918 Fungi UP000027920 656917171 KEF62749.1 565 565 yes 2196750 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 244447 Cynoglossus semilaevis Vertebrates 657744799, 657744797, 657744795 XP_008307602.1, XP_008307601.1, XP_008307600.1 424 430 yes 2196751 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 930990 Botryobasidium botryosum FD-172 SS1 Fungi UP000027195 646285262 KDQ07197.1 514 521 yes 2196752 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 685588 Galerina marginata CBS 339.88 Fungi UP000027222 648169742 KDR83372.1 529 531 no 2196753 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1137138 Pleurotus ostreatus PC15 Fungi UP000027073 646307960 KDQ29104.1 454 456 yes 2196754 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 429131 Trypanosoma rangeli SC58 Invertebrates UP000031737 554936609 ESL08337.1 360 366 yes 2196755 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 32630 synthetic construct Synthetic 649118392 AIC54296.1 489 489 yes 2196756 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3880 Medicago truncatula Plants UP000002051 657383749 AES93831.2 460 463 yes 2196757 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 345 347 no 2196758 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 71804 Trypanosoma grayi Invertebrates 686630417, 657144638 KEG14130.1 XP_009307654.1 611 613 no 2196759 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 71804 Trypanosoma grayi Invertebrates 686631023, 657144259 KEG13809.1 XP_009307957.1 359 361 yes 2196760 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 933084 Jaapia argillacea MUCL 33604 Fungi UP000027265 646400581 KDQ64660.1 520 523 no 2196761 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 926571 Nitrososphaera viennensis EN76 Archaea UP000027093 647811836 AIC15537.1 A0A060HQU2 A0A060HQU2_9ARCH 325 333 no 2196762 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3750 Malus x domestica Plants 658055993, 658055991 XP_008363748.1, XP_008363747.1 504 504 yes 2196763 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 54757 Plasmodium vinckei vinckei Invertebrates UP000030681 669197727, 657009999 KEG03053.1 XP_008623874.1 689 690 yes 2196764 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 685588 Galerina marginata CBS 339.88 Fungi UP000027222 648159093 KDR72825.1 540 540 yes 2196765 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 136037 Zootermopsis nevadensis Invertebrates UP000027135 646707951 KDR14464.1 404 410 yes 2196766 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 144197 Stegastes partitus Vertebrates 657589709 XP_008299257.1 494 495 no 2196767 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 244447 Cynoglossus semilaevis Vertebrates 657741672 XP_008305935.1 493 493 yes 2196768 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1130302 crenarchaeote SCGC AAA261-L14 Archaea 656263215 WP_029209169.1 143 154 no 2196769 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 136037 Zootermopsis nevadensis Invertebrates UP000027135 646710552 KDR16032.1 478 480 yes 2196770 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 429131 Trypanosoma rangeli SC58 Invertebrates UP000031737 554930879 ESL05665.1 613 615 no 2196771 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 102107 Prunus mume Plants 645223873 XP_008218840.1 443 446 yes 2196772 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3750 Malus x domestica Plants 657960961, 657960959 XP_008372063.1, XP_008372062.1 451 455 yes 2196773 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 180498 Jatropha curcas Plants UP000027138 802554777, 643738273 KDP44261.1 XP_012065078.1 506 508 yes 2196774 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 54757 Plasmodium vinckei vinckei Invertebrates UP000030681 669197999, 657010135 KEG03189.1 XP_008624010.1 471 476 yes 2266848 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9244 Calypte anna Vertebrates UP000054308 663265938 XP_008493349.1 427 435 yes 2266849 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1459636 Candidatus Nitrososphaera evergladensis SR1 Archaea UP000028194 665994985 AIF84745.1 A0A075MU96 A0A075MU96_9ARCH 325 333 no 2266850 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456386 uncultured marine thaumarchaeote SAT1000_15_H02 Archaea 663533510 AIF23429.1 A0A075I668 A0A075I668_9ARCH 325 331 no 2266851 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 99158 Hammondia hammondi Invertebrates UP000027470 675122144, 661338124 KEP66251.1 XP_008882959.1 563 569 no 2266852 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 49390 Coffea canephora Plants 661869828 99 99 no 2266853 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1043002 Aureobasidium pullulans var. pullulans EXF-150 Fungi UP000030706 662529690 KEQ87065.1 539 542 yes 2266854 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1457766 uncultured marine group II/III euryarchaeote AD1000_41_D11 Archaea 663503119 AIE93944.1 A0A075FRQ7 A0A075FRQ7_9EURY 95 96 no 2266855 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1455946 uncultured marine thaumarchaeote AD1000_88_E07 Archaea 663506190 AIE96930.1 A0A075FYV3 A0A075FYV3_9ARCH 323 331 no 2266856 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1423351 Rhizoctonia solani 123E Fungi UP000027456 660971913 KEP55522.1 487 493 no 2266857 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456153 uncultured marine thaumarchaeote KM3_44_H07 Archaea 663519922 AIF10270.1 A0A075H518 A0A075H518_9ARCH 324 331 no 2266858 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1280524, 1280523 Stachybotrys chartarum IBT 40293, Stachybotrys chartarum IBT 7711 Fungi UP000028200, UP000028045 667525562, 666410700 KFA54156.1, KEY75218.1 536 536 yes 2266859 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8081 Poecilia reticulata Vertebrates 658907664, 658907662 XP_008436556.1, XP_008436555.1 490 490 yes 2266860 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1263082 Lichtheimia corymbifera JMRC:FSU:9682 Fungi UP000027586 661182890 499 500 yes 2266861 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456536, 1457838, 1457757 uncultured marine group II/III euryarchaeote KM3_88_E02, uncultured marine group II/III euryarchaeote KM3_05_F04, uncultured marine group II/III euryarchaeote AD1000_34_D01 Archaea 663530136, 663507614, 663502537 AIF20130.1, AIE98315.1, AIE93378.1 A0A075FQ79, A0A075HX33, A0A075G2M1 A0A075FQ79_9EURY, A0A075HX33_9EURY, A0A075G2M1_9EURY 368 370 no 2266862 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 482537 Galeopterus variegatus Primates 667264389 XP_008568616.1 489 489 yes 2266863 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1457766 uncultured marine group II/III euryarchaeote AD1000_41_D11 Archaea 663503120 AIE93945.1 A0A075FQL1 A0A075FQL1_9EURY 247 251 no 2266864 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 482537 Galeopterus variegatus Primates 667264392 XP_008568617.1 488 488 yes 2266865 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1502292 Marine Group I thaumarchaeote SCGC AAA799-E16 Archaea UP000028027 851154413, 662557608 KER06202.1 WP_048088556.1 A0A081S5J9 A0A081S5J9_9ARCH 323 331 no 2266866 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1457771 uncultured marine group II/III euryarchaeote AD1000_43_D04 Archaea 663503287 AIE94107.1 A0A075FWV8 A0A075FWV8_9EURY 367 369 no 2266867 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 36022 Pichia fabianii Fungi 663447683 602 604 yes 2266868 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456169 uncultured marine thaumarchaeote KM3_47_G11 Archaea 663520676 AIF11003.1 A0A075HB66 A0A075HB66_9ARCH 324 331 no 2266869 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1283841 Stachybotrys chlorohalonata IBT 40285 Fungi UP000028524 667718791 KFA61183.1 449 456 yes 2266870 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9244 Calypte anna Vertebrates UP000054308 663252114 XP_008489148.1 484 586 yes 2266871 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 69319 Microplitis demolitor Invertebrates 665784300 XP_008557441.1 539 645 yes 2266872 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 482537 Galeopterus variegatus Primates 667250780 XP_008563883.1 427 438 yes 2266873 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6198 Opisthorchis viverrini Invertebrates UP000054324 684411946, 663043274 KER19697.1 XP_009176558.1 536 546 yes 2266874 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3656 Cucumis melo Plants 659108142 XP_008454039.1 403 444 no 2266875 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3656 Cucumis melo Plants 659108140 XP_008454038.1 500 500 yes 2266876 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1043005 Aureobasidium pullulans var. subglaciale EXF-2481 Fungi UP000030641 662535863 KEQ93178.1 445 450 yes 2266877 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1043003 Aureobasidium pullulans var. melanogenum CBS 110374 Fungi UP000030672 662502992 KEQ60615.1 445 450 yes 2266878 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 49390 Coffea canephora Plants 661884644 466 472 yes 2266879 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1280523 Stachybotrys chartarum IBT 7711 Fungi UP000028045 666401221 KEY66984.1 450 457 yes 2266880 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1283842 Stachybotrys chartarum IBT 40288 Fungi UP000028540 667735309 KFA74666.1 450 457 yes 2266881 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 563466 Scedosporium apiospermum Fungi UP000028545 666870823 KEZ46837.1 451 459 yes 2266882 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 49390 Coffea canephora Plants 661885510 338 354 no 2266883 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1456425 uncultured marine group II/III euryarchaeote KM3_205_F07 Archaea 663517210 AIF07636.1 A0A075GUQ3 A0A075GUQ3_9EURY 366 368 no 2266884 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1283841 Stachybotrys chlorohalonata IBT 40285 Fungi UP000028524 667720715 KFA63006.1 534 534 yes 2266885 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9798 Equus przewalskii Mammals 664714441 XP_008514200.1 489 489 yes 2266886 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1457899 uncultured marine group II/III euryarchaeote KM3_156_A06 Archaea 663511692 AIF02281.1 A0A075GDX8 A0A075GDX8_9EURY 366 368 no 2266887 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121845 Diaphorina citri Invertebrates 662221742 XP_008485079.1 251 252 no 2266888 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1456580 uncultured marine group II/III euryarchaeote SAT1000_40_C12 Archaea 663534933 AIF24810.1 A0A075IAJ9 A0A075IAJ9_9EURY 85 86 no 2266889 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 99158 Hammondia hammondi Invertebrates UP000027470 675135064, 661317091 KEP60073.1 XP_008889419.1 1295 1295 no 2266890 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1043003 Aureobasidium pullulans var. melanogenum CBS 110374 Fungi UP000030672 662502607 KEQ60232.1 541 542 yes 2266891 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1455928 uncultured marine thaumarchaeote AD1000_63_F07 Archaea 663504516 AIE95302.1 A0A075G089 A0A075G089_9ARCH 151 159 no 2266892 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8081 Poecilia reticulata Vertebrates 658880462 XP_008423167.1 419 432 yes 2266893 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1456430, 1457848 uncultured marine group II/III euryarchaeote KM3_27_E07, uncultured marine group II/III euryarchaeote KM3_105_H04 Archaea 663517846, 663508464 AIF08255.1, AIE99142.1 A0A075GZ95, A0A075GBW8 A0A075GZ95_9EURY, A0A075GBW8_9EURY 367 369 no 2266894 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 971279, 1343739 Palaeococcus sp. DY20341, Palaeococcus pacificus DY20341 Archaea UP000027981 851302394, 664802001 AIF70234.1 WP_048165705.1 A0A075LV78 A0A075LV78_9EURY 339 344 no 2266895 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1043005 Aureobasidium pullulans var. subglaciale EXF-2481 Fungi UP000030641 662541056 KEQ98356.1 537 537 yes 2266896 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 49390 Coffea canephora Plants 661891741 92 101 no 2266897 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 49390 Coffea canephora Plants 661891742 99 99 no 2266898 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1476192 Aspergillus fumigatus var. RP-2014 Fungi UP000028372 666432746 KEY80318.1 563 565 yes 2266899 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456307 uncultured marine thaumarchaeote KM3_83_D12 Archaea 663528490 AIF18527.1 A0A075HVM7 A0A075HVM7_9ARCH 326 331 no 2266900 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1283842 Stachybotrys chartarum IBT 40288 Fungi UP000028540 667733743 KFA73177.1 536 536 yes 2266901 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 69319 Microplitis demolitor Invertebrates 665798148 XP_008546937.1 351 352 no 2266902 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456128 uncultured marine thaumarchaeote KM3_34_B07 Archaea 663518631 AIF09016.1 A0A075GYN5 A0A075GYN5_9ARCH 323 331 no 2266903 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456485 uncultured marine group II/III euryarchaeote KM3_67_G08 Archaea 663524491 AIF14717.1 A0A075HJY0 A0A075HJY0_9EURY 331 334 no 2266904 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1455906 uncultured marine thaumarchaeote AD1000_31_F12 Archaea 663502246 AIE93094.1 A0A075FP12 A0A075FP12_9ARCH 164 169 no 2266905 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1456334 uncultured marine thaumarchaeote KM3_88_D06 Archaea 663530051 AIF20048.1 A0A075I225 A0A075I225_9ARCH 138 142 no 2266906 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 49390 Coffea canephora Plants 661872726 495 495 yes 2266907 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1457762 uncultured marine group II/III euryarchaeote AD1000_39_C04 Archaea 663502746 AIE93580.1 A0A075FPJ7 A0A075FPJ7_9EURY 280 281 no 2266908 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121845 Diaphorina citri Invertebrates 662184583 XP_008472616.1 240 259 no 2266909 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121845 Diaphorina citri Invertebrates 662184585 XP_008472628.1 96 106 no 2266910 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121845 Diaphorina citri Invertebrates 662184587 XP_008472637.1 371 374 no 2266911 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456117 uncultured marine thaumarchaeote KM3_31_D02 Archaea 663518088 AIF08489.1 A0A075GXE0 A0A075GXE0_9ARCH 326 331 no 2266912 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1280524 Stachybotrys chartarum IBT 40293 Fungi UP000028200 667518008 KFA47430.1 450 457 yes 2266913 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1043004 Aureobasidium pullulans var. namibiae CBS 147.97 Fungi UP000027730 662512196 KEQ69772.1 A0A074WIX1 A0A074WIX1_9PEZI 445 450 yes 2266914 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1043002 Aureobasidium pullulans var. pullulans EXF-150 Fungi UP000030706 662526200 KEQ83582.1 445 451 yes 2266915 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456396 uncultured marine thaumarchaeote SAT1000_23_E11 Archaea 663534160 AIF24061.1 A0A075I5W1 A0A075I5W1_9ARCH 324 331 no 2266916 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 36022 Pichia fabianii Fungi 663443854 425 430 yes 2266917 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1423351 Rhizoctonia solani 123E Fungi UP000027456 660970845 KEP54560.1 485 494 yes 2266918 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3656 Cucumis melo Plants 659110493 XP_008455253.1 471 489 yes 2266919 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1263082 Lichtheimia corymbifera JMRC:FSU:9682 Fungi UP000027586 661182404 427 432 yes 2266920 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456292 uncultured marine thaumarchaeote KM3_78_E10 Archaea 663527536 AIF17681.1 A0A075HMN9 A0A075HMN9_9ARCH 324 331 no 2266921 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 49390 Coffea canephora Plants 661873835 286 321 no 2266922 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1043004 Aureobasidium pullulans var. namibiae CBS 147.97 Fungi UP000027730 662516851 KEQ74414.1 A0A074WS46 A0A074WS46_9PEZI 541 542 yes 2266923 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1456351 uncultured marine thaumarchaeote KM3_98_B07 Archaea 663531117 AIF21085.1 A0A075HZY5 A0A075HZY5_9ARCH 325 331 no 2276468 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 943118 Toxoplasma gondii MAS Invertebrates UP000028821 672577418 KFH15321.1 569 571 no 2276469 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 933077 Toxoplasma gondii VAND Invertebrates UP000028840 672571497 KFH10617.1 555 559 no 2276470 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1138374 Nematocida sp. 1 ERTm6 Fungi UP000054524 672236660 KFG26380.1 417 430 no 2276471 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1301915 Methanocaldococcus sp. JH146 Archaea UP000028781 851373882, 672366904 AIJ06241.1 WP_048202335.1 A0A076LDD9 A0A076LDD9_9EURY 322 323 no 2276472 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 36087 Trichuris trichiura Invertebrates UP000030665 669225072 306 322 yes 2276473 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 857340 Acremonium chrysogenum ATCC 11550 Fungi UP000029964 672796189 KFH46738.1 468 474 yes 2276474 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1276135, 5530 Metarhizium anisopliae ARSEF 549, Metarhizium anisopliae Fungi UP000031186, UP000029112 743635854, 672380653 KID67234.1, KFG82850.1 452 454 yes 2276475 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1069443 Mortierella verticillata NRRL 6337 Fungi 672818571 KFH63472.1 460 463 yes 2276476 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 943118 Toxoplasma gondii MAS Invertebrates UP000028821 672577942 KFH15715.1 1283 1283 no 2276477 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 74873 Anopheles sinensis Invertebrates UP000030765 668451533 KFB40606.1 271 273 no 2276478 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 74873 Anopheles sinensis Invertebrates UP000030765 668451534 KFB40607.1 185 188 no 2276479 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 943119 Toxoplasma gondii p89 Invertebrates UP000028828 672266228 KFG39698.1 555 559 no 2276480 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1229, 314279 Nitrosococcus oceani, Nitrosococcus oceani C-27 Bacteria UP000028833, UP000028839 738617727, 672875526 KFI17841.1 WP_036527560.1 103 105 no 2276481 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 68888 Trichuris suis Invertebrates UP000030764 730369677, 669326934, 669308248 KHJ41452.1, KFD67141.1, KFD51751.1 409 411 yes 2276482 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 36087 Trichuris trichiura Invertebrates UP000030665 669221505 408 414 yes 2276483 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 42345 Phoenix dactylifera Plants 672131775 XP_008789453.1 469 488 yes 2276484 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 42345 Phoenix dactylifera Plants 672131778 XP_008789454.1 473 481 yes 2276485 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1398559 Melanopsichium pennsylvanicum 4 Fungi 673526701 692 693 yes 2276486 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 68888 Trichuris suis Invertebrates UP000030764 669314256 KFD57709.1 429 434 no 2276487 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 42345 Phoenix dactylifera Plants 672162750 XP_008801200.1 502 502 yes 2276488 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29073 Ursus maritimus Mammals 671005805 XP_008693759.1 430 448 yes 2276489 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 943167, 1130820 Toxoplasma gondii FOU, Toxoplasma gondii GAB2-2007-GAL-DOM2 Invertebrates UP000028838, UP000028837 672283208, 672278268 KFG52786.1, KFG49327.1 567 571 no 2276490 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 74873 Anopheles sinensis Invertebrates UP000030765 668448191 KFB37885.1 472 472 yes 2276491 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1069443 Mortierella verticillata NRRL 6337 Fungi 672822999 KFH67893.1 595 603 yes 2276492 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6279 Brugia malayi Invertebrates UP000026912 671418144 471 475 yes 2276493 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 572092 Absidia idahoensis var. thermophila Fungi 671684983 426 431 yes 2276494 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 857340 Acremonium chrysogenum ATCC 11550 Fungi UP000029964 672796802 KFH47345.1 533 533 yes 2276495 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1138374 Nematocida sp. 1 ERTm6 Fungi UP000054524 672237634 KFG27352.1 367 373 yes 2276496 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1398559 Melanopsichium pennsylvanicum 4 Fungi 673527574 589 605 no 2276497 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 85066 Corvus brachyrhynchos Vertebrates UP000052976 669292013 XP_008639094.1 412 438 yes 2276498 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1276135, 5530 Metarhizium anisopliae ARSEF 549, Metarhizium anisopliae Fungi UP000031186, UP000029112 743632541, 672383235 KID63941.1, KFG85351.1 530 530 yes 2276499 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 68888 Trichuris suis Invertebrates UP000030764 669332040 KFD72207.1 429 434 yes 2276500 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 935652 Toxoplasma gondii RUB Invertebrates UP000028834 672302344 KFG65373.1 567 571 no 2276501 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6279 Brugia malayi Invertebrates UP000026912 671410320 389 391 yes 2276502 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 42345 Phoenix dactylifera Plants 672131780 XP_008789455.1 469 474 yes 2276503 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29073 Ursus maritimus Mammals 671013420 XP_008697539.1 489 489 yes 2276504 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29073 Ursus maritimus Mammals 671013422 XP_008697540.1 413 413 yes 2276505 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 572092 Absidia idahoensis var. thermophila Fungi 671684682 499 500 yes 2276506 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 85066 Corvus brachyrhynchos Vertebrates UP000052976 669291181 XP_008638634.1 366 503 yes 2276507 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 933077, 935652 Toxoplasma gondii VAND, Toxoplasma gondii RUB Invertebrates UP000028840, UP000028834 672564624, 672301704 KFH05094.1, KFG64895.1 1283 1283 no 2290645 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 97097 Phaethon lepturus Vertebrates UP000053638 677486314 KFQ75719.1 371 371 no 2290646 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9483 Callithrix jacchus Primates UP000008225 675657710 XP_008994607.1 429 438 no 2290647 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 50452 Arabis alpina Plants UP000029120 674242409 KFK35174.1 495 495 yes 2290648 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420901 Pseudogymnoascus pannorum VKM F-3775 Fungi UP000029338 682307382 KFY16746.1 434 443 yes 2290649 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 43455 Cathartes aura Vertebrates UP000053745 677249777 KFP59290.1 375 375 yes 2290650 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9135 Serinus canaria Vertebrates 683925685 XP_009093173.1 409 521 yes 2290651 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9233 Aptenodytes forsteri Vertebrates UP000053286 675317674 KFM12936.1 405 405 yes 2290652 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1391699 Geomyces pannorum var. pannorum F-3808 Fungi UP000029329 682282495 KFY03317.1 559 559 yes 2290653 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420913 Pseudogymnoascus pannorum VKM F-4518 (FW-2643) Fungi UP000029284 682436469 KFZ01077.1 559 559 yes 2290654 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 188379 Egretta garzetta Vertebrates UP000053119 676827797 KFP21185.1 235 345 no 2290655 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420915 Pseudogymnoascus pannorum VKM F-4520 (FW-2644) Fungi UP000029308 682455040 KFZ13309.1 431 442 yes 2290656 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121530 Tauraco erythrolophus Vertebrates UP000053661 678149810 KFV18961.1 366 366 no 2290657 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420906 Pseudogymnoascus pannorum VKM F-4281 (FW-2241) Fungi UP000029327 682321143 KFY24327.1 431 441 yes 2290658 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9135 Serinus canaria Vertebrates 683908182 XP_009086898.1 477 478 yes 2290659 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 885580 Fukomys damarensis Rodents UP000028990 731194703, 676285950 KFO37767.1 XP_010632950.1 489 489 yes 2290660 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 57068 Acanthisitta chloris Vertebrates UP000053537 677301255 KFP83683.1 354 354 no 2290661 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3708 Brassica napus Plants UP000028999 674933087 447 450 yes 2290662 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420902 Pseudogymnoascus pannorum VKM F-4246 Fungi UP000029299 682293336 KFY08603.1 435 445 yes 2290663 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 57068 Acanthisitta chloris Vertebrates UP000053537 677289186 KFP71614.1 218 219 no 2290664 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5949 Stylonychia lemnae Invertebrates UP000039865 678330254 463 541 yes 2290665 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8897 Chaetura pelagica Vertebrates UP000031515 678121804 KFU96354.1 349 349 no 2290666 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3708 Brassica napus Plants UP000028999 674961483 491 491 yes 2290667 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54380 Cariama cristata Vertebrates UP000054116 677273289 KFP64607.1 373 373 no 2290668 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3708 Brassica napus Plants UP000028999 674946475 447 451 yes 2290669 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 188379 Egretta garzetta Vertebrates UP000053119 697831852, 676820406 KFP15215.1 XP_009636289.1 334 334 no 2290670 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6185 Schistosoma haematobium Invertebrates UP000054474 844858328, 685962097 KGB37578.1 XP_012797340.1 459 503 yes 2290671 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1437433 Pseudogymnoascus pannorum VKM F-3557 Fungi UP000029320 682269024 KFX93671.1 A0A094A6L7 A0A094A6L7_9PEZI 559 559 yes 2290672 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5823 Plasmodium berghei str. ANKA Invertebrates UP000007720 675226872 657 658 yes 2290673 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1026970 Nannospalax galili Rodents 674072825 XP_008843617.1 489 489 yes 2290674 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54374 Mesitornis unicolor Vertebrates UP000053369 677445350 KFQ39726.1 201 202 no 2290675 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 34506 Strongyloides ratti Invertebrates UP000035682 685829553 383 387 yes 2290676 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2162 Methanobacterium formicicum Archaea UP000062768 851111073, 693277063, 683510208 AIS33070.1 WP_048072739.1 A0A090JVP3 A0A090JVP3_METFO 328 329 no 2290677 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8897 Chaetura pelagica Vertebrates UP000031515 678111019 KFU87721.1 230 231 no 2290678 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5949 Stylonychia lemnae Invertebrates UP000039865 678333592 413 418 yes 2290679 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420906 Pseudogymnoascus pannorum VKM F-4281 (FW-2241) Fungi UP000029327 682333717 KFY31590.1 560 560 yes 2290680 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 85066 Corvus brachyrhynchos Vertebrates UP000052976 676423091 KFO64556.1 404 404 yes 2290681 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1296104, 1334442, 1296101, 1296107, 1296110, 1296117, 1296106, 294750 Cryptococcus gattii 99/473, Cryptococcus gattii 2001/935-1, Cryptococcus gattii CBS 10090, Cryptococcus gattii CA1014, Cryptococcus gattii Ram5, Cryptococcus gattii MMRL2647, Cryptococcus gattii LA55, Cryptococcus bacillisporus R265 Fungi UP000054096, UP000053019, UP000054439, UP000053939, UP000053392, UP000053522, UP000053189, UP000029445 761935291, 757395016, 757389844, 757366854, 757336496, 757329742, 757324673, 686623360 KIY56090.1, KIS00314.1, KIR95164.1, KIR72654.1, KIR42520.1, KIR35790.1, KIR30744.1, KGB75330.1 513 520 no 2290682 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9233 Aptenodytes forsteri Vertebrates UP000053286 686600625 XP_009276564.1 379 493 yes 2290683 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9555 Papio anubis Primates UP000028761 685514605 XP_009205180.1 400 400 no 2290684 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5679 Leishmania panamensis Invertebrates UP000063063 731701998, 685205893 AIO00126.1 XP_010700783.1 371 373 yes 2290685 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 328815 Manacus vitellinus Vertebrates UP000053258 675429642 XP_008928804.1 365 376 yes 2290686 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54383 Eurypyga helias Vertebrates UP000054232 678977998 KFV90997.1 359 359 no 2290687 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1503183 Marine Group I thaumarchaeote RSA3 Archaea 851141783, 675343253 KFM16335.1 WP_048083601.1 A0A087RS81 A0A087RS81_9ARCH 190 190 no 2290688 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420911 Pseudogymnoascus pannorum VKM F-4517 (FW-2822) Fungi UP000029270 682415223 KFY86420.1 430 439 yes 2290689 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1026970 Nannospalax galili Rodents 674042313, 674042311 XP_008827017.1, XP_008827016.1 407 438 yes 2290690 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3711 Brassica rapa Plants 685323164, 685323161, 685323159 XP_009151325.1, XP_009151324.1, XP_009151323.1 446 450 yes 2290691 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3708 Brassica napus Plants UP000028999 674861993 216 220 no 2290692 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420913 Pseudogymnoascus pannorum VKM F-4518 (FW-2643) Fungi UP000029284 682417062 KFY87712.1 429 442 yes 2290693 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9597 Pan paniscus Primates UP000065018 675720283 XP_008963571.1 413 413 yes 2290694 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 240206 Pterocles gutturalis Vertebrates UP000053149 678140065 KFV09237.1 376 376 no 2290695 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 84753 Pseudozyma antarctica Fungi UP000053758 674215897 386 410 no 2290696 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 55661 Cuculus canorus Vertebrates UP000053760 676585853 KFO74694.1 448 448 yes 2290697 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5861 Plasmodium yoelii Invertebrates 675238010, 675232770 470 475 yes 2290698 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 407821 Stegodyphus mimosarum Invertebrates UP000054359 675380717 KFM73619.1 305 309 no 2290699 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 31271 Plasmodium chabaudi chabaudi Invertebrates 675221163 471 476 yes 2290700 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9244 Calypte anna Vertebrates UP000054308 676769436 KFO98578.1 481 481 yes 2290701 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9233 Aptenodytes forsteri Vertebrates UP000053286 686617533 XP_009285719.1 405 406 yes 2290702 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 84753 Pseudozyma antarctica Fungi UP000053758 674216687 666 666 yes 2290703 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5823 Plasmodium berghei str. ANKA Invertebrates UP000007720 675227009 471 476 yes 2290704 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 187382 Chlamydotis undulata macqueenii Vertebrates UP000053330 677151505 KFP41908.1 391 391 yes 2290705 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1437433 Pseudogymnoascus pannorum VKM F-3557 Fungi UP000029320 682272031 KFX95671.1 A0A094ACC5 A0A094ACC5_9PEZI 160 161 no 2290706 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9218 Phoenicopterus ruber ruber Vertebrates UP000053700 677500109 KFQ88910.1 356 356 no 2290707 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 118200 Picoides pubescens Vertebrates UP000053875 678202525 KFV69507.1 262 354 no 2290708 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420911, 1420909 Pseudogymnoascus pannorum VKM F-4517 (FW-2822), Pseudogymnoascus pannorum VKM F-4515 (FW-2607) Fungi UP000029270, UP000029302 682425017, 682385014 KFY92823.1, KFY67135.1 559 559 yes 2290709 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1296107, 294750 Cryptococcus gattii CA1014, Cryptococcus bacillisporus R265 Fungi UP000053939, UP000029445 757365186, 686628083 KIR70992.1, KGB79085.1 514 514 yes 2290710 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 328815 Manacus vitellinus Vertebrates UP000053258 675418582 XP_008922666.1 349 350 no 2290711 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1502294 Marine Group I thaumarchaeote SCGC AAA799-O18 Archaea 675341356 KFM14591.1 A0A087RM87 A0A087RM87_9ARCH 239 267 no 2290712 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 328815 Manacus vitellinus Vertebrates UP000053258 679190987 KFW81370.1 319 319 no 2290713 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54374 Mesitornis unicolor Vertebrates UP000053369 677444596 KFQ39378.1 220 315 no 2290714 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420907 Pseudogymnoascus pannorum VKM F-4513 (FW-928) Fungi UP000029288 682340529 KFY35587.1 435 445 yes 2290715 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420901 Pseudogymnoascus pannorum VKM F-3775 Fungi UP000029338 682307916 KFY17035.1 559 559 yes 2290716 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 407821 Stegodyphus mimosarum Invertebrates UP000054359 675388725 KFM81622.1 415 420 yes 2290717 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420907 Pseudogymnoascus pannorum VKM F-4513 (FW-928) Fungi UP000029288 682336890 KFY33303.1 559 559 yes 2290718 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 57068 Acanthisitta chloris Vertebrates UP000053537 677996188 XP_009076399.1 350 350 no 2290719 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420912 Pseudogymnoascus pannorum VKM F-103 Fungi UP000029295 682401904 KFY78464.1 432 441 yes 2290720 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 34506 Strongyloides ratti Invertebrates UP000035682 685828035 470 476 yes 2290721 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3708 Brassica napus Plants UP000028999 674855201 205 217 no 2290722 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 905826, 1503183, 1502291 Marine Group I thaumarchaeote RSA3, Marine Group I thaumarchaeote SCGC AAA799-D11 Archaea UP000029386 851141820, 675343229, 675341694 KFM16317.1, KFM14908.1 WP_048083615.1 A0A087RS63, A0A087RN54 A0A087RS63_9ARCH, A0A087RN54_9ARCH 322 331 no 2290723 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 57421 Merops nubicus Vertebrates UP000052967 675607089 XP_008947420.1 241 241 yes 2290724 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3711 Brassica rapa Plants 685364947 XP_009116630.1 487 487 yes 2290725 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420914 Pseudogymnoascus pannorum VKM F-4519 (FW-2642) Fungi UP000029315 682444808 KFZ06056.1 432 441 yes 2290726 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420912 Pseudogymnoascus pannorum VKM F-103 Fungi UP000029295 682405755 KFY81136.1 559 559 yes 2290727 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6211 Echinococcus multilocularis Invertebrates UP000017246 674266502 456 458 yes 2290728 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5679 Leishmania panamensis Invertebrates UP000063063 731706766, 685207315 AIO01544.1 XP_010702344.1 664 664 yes 2290729 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 30419 Opisthocomus hoazin Vertebrates UP000053605 677542271 KFR03679.1 350 350 no 2290730 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 85066 Corvus brachyrhynchos Vertebrates UP000052976 676422454 KFO64184.1 346 346 no 2290731 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420915 Pseudogymnoascus pannorum VKM F-4520 (FW-2644) Fungi UP000029308 682448870 KFZ08876.1 559 559 yes 2290732 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 118200 Picoides pubescens Vertebrates UP000053875 678201508 KFV68490.1 391 391 yes 2290733 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420902 Pseudogymnoascus pannorum VKM F-4246 Fungi UP000029299 682304270 KFY14951.1 559 559 yes 2290734 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5861 Plasmodium yoelii Invertebrates 675237873, 675232632 676 677 yes 2290735 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 31271 Plasmodium chabaudi chabaudi Invertebrates 675221026 664 665 yes 2290736 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 407821 Stegodyphus mimosarum Invertebrates UP000054359 675382697 KFM75594.1 484 486 yes 2290737 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 57068 Acanthisitta chloris Vertebrates UP000053537 677588779 XP_009071748.1 255 256 yes 2290738 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420910, 1420908 Pseudogymnoascus pannorum VKM F-4516 (FW-969), Pseudogymnoascus pannorum VKM F-4514 (FW-929) Fungi UP000029268, UP000029260 682386034, 682363844 KFY67978.1, KFY50863.1 431 440 yes 2290739 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3075 Auxenochlorella protothecoides Plants UP000028924 760442797, 675353131 KFM25571.1 XP_011398467.1 417 593 no 2290740 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6211 Echinococcus multilocularis Invertebrates UP000017246 674267649 413 425 yes 2290741 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 188344 Leptosomus discolor Vertebrates UP000053001 677368074 KFP95768.1 378 378 no 2290742 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 328815 Manacus vitellinus Vertebrates UP000053258 679197046 KFW86436.1 232 233 no 2290743 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6185 Schistosoma haematobium Invertebrates UP000054474 844839859, 685957109 KGB33259.1 XP_012793014.1 432 451 yes 2290744 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420910, 1420908 Pseudogymnoascus pannorum VKM F-4516 (FW-969), Pseudogymnoascus pannorum VKM F-4514 (FW-929) Fungi UP000029268, UP000029260 682374120, 682353951 KFY58889.1, KFY44482.1 559 559 yes 2290745 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1502290 Marine Group I thaumarchaeote SCGC AAA799-D07 Archaea 851143268, 675347741 KFM20651.1 WP_048084018.1 A0A087S4J7 A0A087S4J7_9ARCH 326 331 no 2290746 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420909 Pseudogymnoascus pannorum VKM F-4515 (FW-2607) Fungi UP000029302 682366314 KFY52707.1 425 437 yes 2290747 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 128390 Nipponia nippon Vertebrates UP000053283 677538592 KFR00306.1 391 391 yes 2290748 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 885580 Fukomys damarensis Rodents UP000028990 731255600, 731255598, 676270288 KFO25512.1 XP_010640444.1, XP_010640443.1 439 461 yes 2290749 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9597 Pan paniscus Primates UP000065018 675740039 XP_008968211.1 419 427 no 2290750 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9598, 9597 Pan troglodytes, Pan paniscus Primates UP000002277 UP000002277, UP000065018 694965405, 675740034 XP_009429836.1, XP_008968210.1 423 453 yes 2290751 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1420914 Pseudogymnoascus pannorum VKM F-4519 (FW-2642) Fungi UP000029315 682453168 KFZ12033.1 559 559 yes 2290752 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1391699 Geomyces pannorum var. pannorum F-3808 Fungi UP000029329 682280424 KFY01743.1 431 440 yes 2290753 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3075 Auxenochlorella protothecoides Plants UP000028924 760444871, 675354126 KFM26566.1 XP_011399504.1 420 432 yes 2306391 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9598 Pan troglodytes Primates UP000002277 UP000002277 694965408 XP_009429837.1 425 432 no 2306392 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9598 Pan troglodytes Primates UP000002277 UP000002277 694965403 XP_009429835.1 458 537 yes 2306393 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4096 Nicotiana sylvestris Plants 698440171 XP_009759721.1 468 480 yes 2306394 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 128390 Nipponia nippon Vertebrates UP000053283 694850690 XP_009466606.1 399 425 yes 2306395 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4428 Ceratophyllum demersum Plants 700255060 AIU49150.1 208 208 no 2306396 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13419 Chimonanthus praecox Plants 700255062 AIU49151.1 340 342 no 2306397 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 101712 Pandanus utilis Plants 700255064 AIU49152.1 340 342 no 2306398 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4686 Asparagus officinalis Plants 700255066 AIU49153.1 340 342 no 2306399 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 158573 Aristolochia tagala Plants 700255068 AIU49154.1 339 341 no 2306400 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4909 Pichia kudriavzevii Fungi UP000029867 695112720 KGK39261.1 608 768 yes 2306401 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 128390 Nipponia nippon Vertebrates UP000053283 694845034 XP_009463469.1 409 415 yes 2306402 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 50402 Charadrius vociferus Vertebrates UP000053858 697456162 KGL93023.1 392 392 yes 2306403 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 218851 Aquilegia coerulea Plants 700255018 AIU49129.1 340 342 no 2306404 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 14027 Trachycarpus fortunei Plants 700255121 AIU49180.1 341 342 no 2306405 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4426 Cabomba caroliniana Plants 700255123 AIU49181.1 235 236 no 2306406 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 176057 Nestor notabilis Vertebrates UP000053840 701303049 XP_010012116.1 316 316 no 2306407 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 5643 Pycnoporus cinnabarinus Fungi UP000029665 691793515 556 593 no 2306408 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4098 Nicotiana tomentosiformis Plants 697115094 XP_009611471.1 470 480 yes 2306409 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1505907 Thermococcus sp. A501 Archaea UP000029980 700302821 AIU69640.1 A0A097QT35 A0A097QT35_9EURY 333 341 no 2306410 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 304 309 no 2306411 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1485682 Microsporidia sp. JFP-2104 Fungi UP000029725 692170414 KGG52735.1 403 407 yes 2306412 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4911 Kluyveromyces marxianus Fungi UP000056224 693900717 590 591 yes 2306413 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5643 Pycnoporus cinnabarinus Fungi UP000029665 691790502 516 520 yes 2306414 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 92927 Sarcandra glabra Plants 700255038 AIU49139.1 341 343 no 2306415 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 15368 Brachypodium distachyon Plants UP000008810 UP000008810 700255032 AIU49136.1 339 343 no 2306416 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 199225 Pinellia ternata Plants 700255030 AIU49135.1 341 342 no 2306417 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4465 Acorus calamus Plants 700255036 AIU49138.1 339 341 no 2306418 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3641 Theobroma cacao Plants UP000026915 700255034 AIU49137.1 341 342 no 2306419 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54380 Cariama cristata Vertebrates UP000054116 698441929 XP_009699163.1 241 242 no 2306420 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13429 Cinnamomum camphora Plants 700255109 AIU49174.1 340 342 no 2306421 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1560471 Ceratophyllum platyacanthum subsp. oryzetorum Plants 700255107 AIU49173.1 104 104 no 2306422 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4236 Lactuca sativa Plants 700255105 AIU49172.1 339 341 no 2306423 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 98039 Thellungiella parvula Plants 700255102 AIU49171.1 340 342 no 2306424 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 57918 Fragaria vesca Plants 700255100 AIU49170.1 341 342 no 2306425 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 30455 Fulmarus glacialis Vertebrates UP000053806 697040009 XP_009582560.1 151 152 no 2306426 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121530 Tauraco erythrolophus Vertebrates UP000053661 701367365 XP_009986075.1 365 366 no 2306427 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 27334 Penicillium expansum Fungi UP000030143 700459603 KGO48997.1 429 435 yes 2306428 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 304 309 no 2306429 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4641 Musa acuminata Plants 700255028 AIU49134.1 316 317 no 2306430 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 82312 Lilium brownii Plants 700255024 AIU49132.1 231 233 no 2306431 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 85856 Magnolia denudata Plants 700255026 AIU49133.1 341 342 no 2306432 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 59689 Arabidopsis lyrata Plants 700255020 AIU49130.1 339 342 no 2306433 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3702 Arabidopsis thaliana Plants UP000006548 UP000006548 700255022 AIU49131.1 339 342 no 2306434 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 40296 Penicillium italicum Fungi UP000030104 700493416 KGO77309.1 575 575 yes 2306435 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8897 Chaetura pelagica Vertebrates UP000031515 701434256 XP_010005014.1 356 382 no 2306436 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 140101 Platanus x acerifolia Plants 700255111 AIU49175.1 202 203 no 2306437 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3311 Ginkgo biloba Plants 700255113 AIU49176.1 339 342 no 2306438 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 16752 Houttuynia cordata Plants 700255115 AIU49177.1 340 342 no 2306439 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4577 Zea mays Plants UP000007305 700255117 AIU49178.1 340 343 no 2306440 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 15000 Alisma plantago-aquatica Plants 700255119 AIU49179.1 341 342 no 2306441 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2226 Methanococcoides methylutens Archaea 695944260 KGK98218.1 A0A099T244 A0A099T244_METMT 330 332 no 2306442 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 40296 Penicillium italicum Fungi UP000030104 700488716 KGO73918.1 431 435 yes 2306443 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 214687 Musa acuminata subsp. malaccensis Plants UP000012960 695027711 XP_009401205.1 484 486 yes 2306444 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54380 Cariama cristata Vertebrates UP000054116 698433244 XP_009697639.1 372 373 no 2306445 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4096 Nicotiana sylvestris Plants 698486590 XP_009790014.1 497 497 yes 2306446 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4096 Nicotiana sylvestris Plants 698486592 XP_009790015.1 392 395 yes 2306447 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 70448 Ostreococcus tauri Plants UP000009170 693496793 423 425 yes 2306448 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4911 Kluyveromyces marxianus Fungi UP000056224 693905132 422 426 yes 2306449 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 225117 Pyrus x bretschneideri Plants 694384646, 694384557 XP_009368210.1, XP_009368169.1 504 504 yes 2306450 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121530 Tauraco erythrolophus Vertebrates UP000053661 701365599 XP_009985808.1 249 250 no 2306451 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1318460 Fusarium sp. FIESC_5 CS3069 Fungi 695124061 537 537 yes 2306452 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 118200 Picoides pubescens Vertebrates UP000053875 699669332 XP_009900324.1 395 412 yes 2306453 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 55661 Cuculus canorus Vertebrates UP000053760 696975445 XP_009557245.1 454 456 yes 2306454 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 30455 Fulmarus glacialis Vertebrates UP000053806 697018133 XP_009570449.1 172 172 no 2306455 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 225117 Pyrus x bretschneideri Plants 694372808, 694372805 XP_009363671.1, XP_009363670.1 447 451 yes 2306456 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 214687 Musa acuminata subsp. malaccensis Plants UP000012960 694998182 XP_009403226.1 507 508 yes 2306457 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4909 Pichia kudriavzevii Fungi UP000029867 695111877 KGK38428.1 415 418 yes 2306458 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9209 Phalacrocorax carbo Vertebrates UP000053238 695158099 XP_009507106.1 333 334 yes 2306459 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4098 Nicotiana tomentosiformis Plants 697106401 XP_009607041.1 497 497 yes 2306460 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 57397 Apaloderma vittatum Vertebrates UP000054244 699577762 XP_009876947.1 253 254 no 2306461 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8897 Chaetura pelagica Vertebrates UP000031515 701382134 XP_009993432.1 316 395 yes 2306462 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4558 Sorghum bicolor Plants UP000000768 UP000018409 700255098 AIU49169.1 339 343 no 2306463 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4555 Setaria italica Plants UP000004995 700255094 AIU49167.1 339 343 no 2306464 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4081 Solanum lycopersicum Plants UP000004994 UP000004994 700255096 AIU49168.1 341 342 no 2306465 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 569628 Dioscorea oppositifolia Plants 700255090 AIU49165.1 248 250 no 2306466 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 55960 Yucca filamentosa Plants 700255092 AIU49166.1 340 342 no 2306467 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 441894 Struthio camelus australis Vertebrates UP000053584 697500222 XP_009679261.1 316 317 no 2306468 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3988 Ricinus communis Plants UP000008311 700255088 AIU49164.1 341 342 no 2306469 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3885 Phaseolus vulgaris Plants UP000000226 700255086 AIU49163.1 340 342 no 2306470 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 38727 Panicum virgatum Plants 700255084 AIU49162.1 339 343 no 2306471 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3760 Prunus persica Plants UP000006882 700255082 AIU49161.1 341 342 no 2306472 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3694 Populus trichocarpa Plants UP000006729 UP000006729 700255080 AIU49160.1 337 339 no 2306473 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 27334 Penicillium expansum Fungi UP000030143 700451205 KGO41251.1 569 569 yes 2306474 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 30419 Opisthocomus hoazin Vertebrates UP000053605 700377459 XP_009943240.1 353 353 no 2306475 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 50402 Charadrius vociferus Vertebrates UP000053858 699664072 XP_009883166.1 396 426 yes 2306476 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 50402 Charadrius vociferus Vertebrates UP000053858 699665733 XP_009883528.1 400 477 no 2306477 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 225117 Pyrus x bretschneideri Plants 694418972, 694418969 XP_009337459.1, XP_009337458.1 446 450 yes 2306478 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 13007 Chloranthus japonicus Plants 700255058 AIU49149.1 341 343 no 2306479 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3847 Glycine max Plants UP000008827 UP000008827 700255050 AIU49145.1 340 342 no 2306480 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 114516 Illicium henryi Plants 700255052 AIU49146.1 340 342 no 2306481 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 153572 Buxus sinica Plants 700255054 AIU49147.1 341 342 no 2306482 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 203638 Iris japonica Plants 700255056 AIU49148.1 341 342 no 2306483 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 188344 Leptosomus discolor Vertebrates UP000053001 700407692 XP_009949342.1 376 377 no 2306484 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 118200 Picoides pubescens Vertebrates UP000053875 699675701 XP_009901686.1 384 546 yes 2306485 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 71139 Eucalyptus grandis Plants UP000030711 700255048 AIU49144.1 342 343 no 2306486 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 29730 Gossypium raimondii Plants UP000032304 700255042 AIU49141.1 340 342 no 2306487 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 85681 Citrus clementina Plants UP000030687 700255040 AIU49140.1 341 343 no 2306488 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 2711 Citrus sinensis Plants UP000027120 700255046 AIU49143.1 242 242 no 2306489 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 81985 Capsella rubella Plants UP000029121 700255044 AIU49142.1 340 342 no 2306490 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 188379 Egretta garzetta Vertebrates UP000053119 697845935 XP_009643336.1 412 487 yes 2306491 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 55661 Cuculus canorus Vertebrates UP000053760 696979141 XP_009558558.1 418 425 yes 2306492 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 27334 Penicillium expansum Fungi UP000030143 700461342, 700454308 KGO50523.1, KGO44154.1 569 569 yes 2306493 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 70448 Ostreococcus tauri Plants UP000009170 693499198 503 504 yes 2306494 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4113 Solanum tuberosum Plants UP000011115 700255078 AIU49159.1 341 342 no 2306495 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4155 Mimulus guttatus Plants UP000030748 700255076 AIU49158.1 340 341 no 2306496 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3983 Manihot esculenta Plants 700255074 AIU49157.1 280 285 no 2306497 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 4628 Canna indica Plants 700255072 AIU49156.1 341 342 no 2306498 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3880 Medicago truncatula Plants UP000002051 700255070 AIU49155.1 339 342 no 2306499 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 176057 Nestor notabilis Vertebrates UP000053840 701296992 XP_010008754.1 318 320 yes 2306500 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 27334 Penicillium expansum Fungi UP000030143 700475872, 700469252 KGO63721.1, KGO57695.1 429 435 yes 2306501 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1485682 Microsporidia sp. JFP-2104 Fungi UP000029725 692169668 KGG52137.1 418 794 yes 2344528 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094983 Candida albicans P94015 Fungi UP000030163 703959981 KGQ86321.1 417 417 yes 2344529 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5141 Neurospora crassa Fungi UP000053122 725977321 KHE80719.1 447 458 yes 2344530 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1095000 Candida albicans P78042 Fungi UP000030499 723203698 KHC77385.1 363 400 no 2344531 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094992 Candida albicans P37037 Fungi UP000030164 703987177 KGR16153.1 529 529 yes 2344532 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094988 Candida albicans GC75 Fungi UP000030162 703967874 KGQ97018.1 529 529 yes 2344533 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 502779 Paracoccidioides brasiliensis Pb01 Fungi UP000002059 701690829 EEH35167.2 444 454 yes 2344534 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1094989 Candida albicans P78048 Fungi UP000030161 703980811 KGR09825.1 319 319 no 2344535 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094995, 1094999, 1094998, 1094983 Candida albicans P75016, Candida albicans P76067, Candida albicans P76055, Candida albicans P94015 Fungi UP000030384, UP000030349, UP000030346, UP000030163 723198751, 723165625, 723164171, 703962812 KHC72481.1, KHC39636.1, KHC38195.1, KGQ89125.1 418 426 yes 2344536 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1094998 Candida albicans P76055 Fungi UP000030346 723160893 KHC34936.1 54 54 no 2344537 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1094998 Candida albicans P76055 Fungi UP000030346 723160892 KHC34935.1 319 319 no 2344538 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 237561, 1094993 Candida albicans SC5314, Candida albicans P37039 Fungi UP000000559 UP000030576, UP000030453 723204319, 723179166 KHC78000.1, KHC53043.1 529 529 yes 2344539 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094993 Candida albicans P37039 Fungi UP000030453 723179185 KHC53062.1 529 529 yes 2344540 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 39432 Saimiri boliviensis boliviensis Primates 725589649 XP_010345758.1 333 397 no 2344541 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 39432 Saimiri boliviensis boliviensis Primates 725589647 XP_010345757.1 413 413 yes 2344542 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094994 Candida albicans P75010 Fungi UP000030551 723189152 KHC62971.1 414 414 yes 2344543 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094984 Candida albicans P87 Fungi UP000030189 712858500 KGU07546.1 529 529 yes 2344544 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1094986, 1094989 Candida albicans P60002, Candida albicans P78048 Fungi UP000030594, UP000030161 723176711, 703980830 KHC50628.1, KGR09844.1 249 250 no 2344545 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1094997 Candida albicans P75063 Fungi UP000030191 712881538 KGU29300.1 144 144 no 2344546 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094999 Candida albicans P76067 Fungi UP000030349 723161691 KHC35729.1 529 529 yes 2344547 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1094999 Candida albicans P76067 Fungi UP000030349 723161672 KHC35710.1 319 319 no 2344548 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094981 Candida albicans 12C Fungi UP000030187 712681217 KGT68314.1 529 529 yes 2344549 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094985 Candida albicans P37005 Fungi UP000030160 703963729 KGQ90035.1 529 529 yes 2344550 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 58291 Rhizopus microsporus Fungi UP000054919 727133007 545 546 yes 2344551 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1165368 Candida albicans Ca6 Fungi UP000030442 723167528 KHC41531.1 383 383 yes 2344552 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 61622 Rhinopithecus roxellana Primates 724867054 XP_010370202.1 261 261 no 2344553 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 61622 Rhinopithecus roxellana Primates 724867051 XP_010370201.1 489 489 yes 2344554 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 932674 Corvus cornix cornix Vertebrates 727026861 XP_010400925.1 342 525 yes 2344555 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54374 Mesitornis unicolor Vertebrates UP000053369 704580303 XP_010188244.1 217 315 no 2344556 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 932674 Corvus cornix cornix Vertebrates 727057078 XP_010407240.1 441 451 yes 2344557 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 237561 Candida albicans SC5314 Fungi UP000000559 UP000030576 723213269, 723204338 KHC86870.1, KHC78019.1 529 529 yes 2344558 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 100784 Balearica pavonina gibbericeps Vertebrates UP000053309 723551996 XP_010298594.1 314 315 no 2344559 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1165368 Candida albicans Ca6 Fungi UP000030442 723167547 KHC41550.1 383 383 yes 2344560 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 187382 Chlamydotis undulata macqueenii Vertebrates UP000053330 705680989 XP_010118659.1 390 391 yes 2344561 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1094991 Candida albicans P34048 Fungi UP000030193 712878101 KGU25920.1 319 319 no 2344562 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094986 Candida albicans P60002 Fungi UP000030594 723177226 KHC51137.1 529 529 yes 2344563 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1095000 Candida albicans P78042 Fungi UP000030499 723203679 KHC77366.1 443 443 yes 2344564 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54374 Mesitornis unicolor Vertebrates UP000053369 704582540 XP_010188908.1 200 201 no 2344565 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1094998, 1094996 Candida albicans P76055, Candida albicans P57055 Fungi UP000030346, UP000030186 723160912, 712882121, 712882102 KHC34955.1, KGU29865.1, KGU29846.1 54 54 no 2344566 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 58291 Rhizopus microsporus Fungi UP000054919 727151408 545 546 yes 2344567 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 97097 Phaethon lepturus Vertebrates UP000053638 723138655 XP_010286128.1 370 371 no 2344568 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4432 Nelumbo nucifera Plants 719963227 XP_010249074.1 513 516 yes 2344569 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54383 Eurypyga helias Vertebrates UP000054232 704242354 XP_010145223.1 154 155 no 2344570 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1094991 Candida albicans P34048 Fungi UP000030193 712878120 KGU25939.1 319 356 no 2344571 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 97097 Phaethon lepturus Vertebrates UP000053638 723152312 XP_010293687.1 207 208 no 2344572 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 61622 Rhinopithecus roxellana Primates 724943241 XP_010386806.1 350 363 yes 2344573 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094994, 1094982, 1094987, 1094988, 237561 Candida albicans P75010, Candida albicans L26, Candida albicans 19F, Candida albicans GC75, Candida albicans SC5314 Fungi UP000000559 UP000030551, UP000030190, UP000030192, UP000030162, UP000030576 723189171, 712861580, 712860035, 703967893 KHC62990.1, KGU10590.1, KGU09060.1, KGQ97037.1 Q59SJ9 DPH21_CANAL Diphthamide biosynthesis protein 2-1 529 529 yes 2344574 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4432 Nelumbo nucifera Plants 720034110 XP_010266635.1 449 464 yes 2344575 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094990 Candida albicans P57072 Fungi UP000030165 703978979 KGR08015.1 529 529 yes 2344576 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094982, 1094987, 1094984, 237561 Candida albicans L26, Candida albicans 19F, Candida albicans P87, Candida albicans SC5314 Fungi UP000000559 UP000030190, UP000030192, UP000030189, UP000030576 712861561, 712860016, 712858481 KGU10571.1, KGU09041.1, KGU07527.1 A0A1D8PL26 DPH22_CANAL Diphthamide biosynthesis protein 2-2 529 529 yes 2344577 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 58291 Rhizopus microsporus Fungi UP000054919 727153469 427 429 yes 2344578 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1245745 Beauveria bassiana D1-5 Fungi UP000030106 701778222 KGQ11815.1 528 528 yes 2344579 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 61622 Rhinopithecus roxellana Primates 724943239 XP_010386805.1 419 438 yes 2344580 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 15368 Brachypodium distachyon Plants UP000008810 UP000008810 721667464 XP_010235961.1 469 470 yes 2344581 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094981 Candida albicans 12C Fungi UP000030187 712681198 KGT68295.1 529 529 yes 2344582 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094990 Candida albicans P57072 Fungi UP000030165 703978960 KGR07996.1 529 529 yes 2344583 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 58291 Rhizopus microsporus Fungi UP000054919 727139238 172 179 no 2344584 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 54383 Eurypyga helias Vertebrates UP000054232 704239542 XP_010160010.1 358 359 no 2344585 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094992 Candida albicans P37037 Fungi UP000030164 703991974 KGR20934.1 418 426 yes 2344586 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5141 Neurospora crassa Fungi UP000053122 725979263 KHE82518.1 598 602 yes 2344587 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1094997 Candida albicans P75063 Fungi UP000030191 712881557 KGU29319.1 144 181 no 2344588 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1245745 Beauveria bassiana D1-5 Fungi UP000030106 701774243 KGQ08533.1 458 463 yes 2344589 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 94827 Tinamus guttatus Vertebrates UP000053641 719763637 XP_010216737.1 415 538 no 2344590 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094992 Candida albicans P37037 Fungi UP000030164 703987158 KGR16134.1 529 529 yes 2344591 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 240206 Pterocles gutturalis Vertebrates UP000053149 704486824 XP_010074550.1 374 375 no 2344592 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1094995 Candida albicans P75016 Fungi UP000030384 723195341 KHC69106.1 529 566 yes 2373174 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1442369 Rhinocladiella mackenziei CBS 650.93 Fungi UP000053617 915056238, 759327777 KIX04106.1 XP_013271242.1 431 439 yes 2373175 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 104421 Camponotus floridanus Invertebrates UP000000311 752866254 XP_011269613.1 452 473 yes 2373176 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 90675 Camelina sativa Plants 727454363, 727454365, 727454367, 727454369, 727454371, 727454373, 727454375 XP_010509044.1, XP_010509045.1, XP_010509047.1, XP_010509048.1, XP_010509049.1, XP_010509050.1, XP_010509051.1 492 493 yes 2373177 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 870435 Pisolithus tinctorius Marx 270 Fungi UP000054217 752340084 KIN99190.1 487 490 yes 2373178 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9838 Camelus dromedarius Mammals 744571170 XP_010980608.1 489 489 yes 2373179 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9838 Camelus dromedarius Mammals 744571173 XP_010980609.1 261 261 no 2373180 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 35722 Parasitella parasitica Fungi UP000054107 758367695 459 661 yes 2373181 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 132908 Pteropus vampyrus Mammals 759141514 XP_011365839.1 485 485 yes 2373182 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29730 Gossypium raimondii Plants UP000032304 823176376, 763769983 KJB37198.1 XP_012486426.1 516 524 yes 2373183 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 990650 Sphaerobolus stellatus SS14 Fungi UP000054279 749880832 KIJ50390.1 540 540 yes 2373184 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1603295 fungal sp. No.11243 Fungi UP000054361 752280708 436 444 yes 2373185 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 348802 Exophiala xenobiotica Fungi UP000054342 915188040, 759282128 KIW58631.1 XP_013319215.1 438 444 yes 2373186 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1579376 archaeon GW2011_AR18 Archaea 735019354 KHO53232.1 A0A0B3B1Q8 A0A0B3B1Q8_9ARCH 327 329 no 2373187 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 212818 Exophiala mesophila Fungi UP000054302 759220654 KIV97991.1 438 448 yes 2373188 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8208 Notothenia coriiceps Vertebrates 736174653 XP_010766870.1 491 491 yes 2373189 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 64838 Fopius arisanus Invertebrates 755927023, 755927026, 755714416 JAG77990.1 XP_011302840.1, XP_011302848.1 454 464 yes 2373190 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9685 Felis catus Mammals UP000011712 UP000011712 755789070 XP_003996479.2 426 440 yes 2373191 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9646 Ailuropoda melanoleuca Mammals UP000008912 752424246 XP_011231051.1 413 413 yes 2373192 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 58291 Rhizopus microsporus Fungi UP000054919 729712489 425 428 yes 2373193 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1081103 Metarhizium album ARSEF 1941 Fungi UP000030816 734658783 KHN95846.1 454 457 yes 2373194 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 994086 Hydnomerulius pinastri MD-312 Fungi UP000053820 749899606 KIJ67158.1 516 516 yes 2373195 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 332 333 no 2373196 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294314, 1294315 Saccharomyces cerevisiae YJM541, Saccharomyces cerevisiae YJM554 Fungi UP000032934, UP000032958 767033131, 767033773 AJS34501.1, AJS34801.1 528 534 yes 2373197 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1442369 Rhinocladiella mackenziei CBS 650.93 Fungi UP000053617 915076117, 759330639 KIX06966.1 XP_013274102.1 568 569 yes 2373198 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29159 Crassostrea gigas Invertebrates UP000005408 762132011 XP_011449187.1 456 459 yes 2373199 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 565033 Geoglobus sp. SBH6 Archaea UP000030624 851158747, 728874959 AIY89270.1 WP_048090463.1 A0A0A7GB65 A0A0A7GB65_9EURY 317 320 no 2373200 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1016849 Exophiala sp. SST-2011 Fungi UP000053599 759200126 KIV77547.1 560 560 yes 2373201 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 215358 Larimichthys crocea Vertebrates UP000054355 734597346, 734597348 XP_010741719.1, XP_010741727.1 493 494 yes 2373202 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1398154 Sporothrix brasiliensis 5110 Fungi UP000031575 748537282 KIH87591.1 559 559 yes 2373203 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 326594 Ceratosolen solmsi marchali Invertebrates 766929282 XP_011496725.1 469 478 yes 2373204 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 443821 Cerapachys biroi Invertebrates UP000053097 759066150 XP_011342519.1 461 474 yes 2373205 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 90675 Camelina sativa Plants 727485435 XP_010418633.1 381 412 yes 2373206 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 90675 Camelina sativa Plants 727601711 XP_010473829.1 325 372 yes 2373207 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1398154 Sporothrix brasiliensis 5110 Fungi UP000031575 748535997 KIH86307.1 515 520 yes 2373208 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 930991 Paxillus rubicundulus Ve08.2h10 Fungi UP000054538 751058502 KIK93395.1 133 214 no 2373209 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9646 Ailuropoda melanoleuca Mammals UP000008912 752398527 XP_002918097.2 433 449 yes 2373210 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28588 Bactrocera cucurbitae Invertebrates 751440881 XP_011192088.1 476 479 yes 2373211 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 64838 Fopius arisanus Invertebrates 755929994, 755929997, 755653493 JAG71833.1 XP_011312587.1, XP_011312596.1 407 410 yes 2373212 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 944288 Plicaturopsis crispa FD-325 SS-3 Fungi UP000053263 749771470 KII95800.1 527 528 no 2373213 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 51022 Ancylostoma duodenale Invertebrates UP000054047 748353148 KIH49260.1 135 137 no 2373214 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 930991 Paxillus rubicundulus Ve08.2h10 Fungi UP000054538 751039679 KIK76859.1 522 524 no 2373215 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9103 Meleagris gallopavo Vertebrates UP000001645 733915618 XP_010720021.1 413 419 yes 2373216 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 765440 Piloderma croceum F 1598 Fungi UP000054166 751739574 KIM87854.1 503 503 yes 2373217 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294356 Saccharomyces cerevisiae YJM1383 Fungi UP000033196 767173162 AJS47400.1 528 534 yes 2373218 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8090 Oryzias latipes Vertebrates UP000001038 765138325 XP_011480712.1 414 428 yes 2373219 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8090 Oryzias latipes Vertebrates UP000001038 765138327 XP_011480713.1 383 398 yes 2373220 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8090 Oryzias latipes Vertebrates UP000001038 765138322 XP_011480711.1 424 439 yes 2373221 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9785 Loxodonta africana Mammals UP000007646 731497911 XP_010593592.1 413 413 yes 2373222 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9785 Loxodonta africana Mammals UP000007646 731497913 XP_010593593.1 335 397 no 2373223 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 664439 Paxillus involutus ATCC 200175 Fungi UP000053647 749822831 KIJ04981.1 511 511 yes 2373224 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1472165 Talaromyces cellulolyticus Fungi UP000053095 748556773 423 426 yes 2373225 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1128425 Fistulina hepatica ATCC 64428 Fungi UP000054144 761923270 KIY44642.1 479 479 yes 2373226 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1579367 archaeon GW2011_AR5 Archaea 735014335 KHO48388.1 A0A0B3A7M8 A0A0B3A7M8_9ARCH 296 296 no 2373227 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1354746 Ordospora colligata OC4 Fungi UP000031056 734519039 KHN69360.1 344 346 yes 2373228 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 253628 Ochroconis gallopava Fungi UP000053259 759222337 KIV99357.1 561 561 yes 2373229 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 51953 Elaeis guineensis Plants 743853659 XP_010940709.1 470 474 yes 2373230 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1582439 Candidatus Nitrosopumilus sp. D3C Archaea UP000032027 756792293 AJM91706.1 A0A0C5BTU3 A0A0C5BTU3_9ARCH 324 331 no 2373231 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579374 archaeon GW2011_AR16 Archaea UP000053740 735017352 KHO51336.1 A0A0B3ASE4 A0A0B3ASE4_9ARCH 219 223 no 2373232 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1276136 Metarhizium guizhouense ARSEF 977 Fungi UP000031192 743661276 KID88494.1 452 454 yes 2373233 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 913025 Thermococcus sp. PK Archaea 757147848 WP_042702048.1 337 345 no 2373234 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294333, 1294376, 1294378, 1294380 Saccharomyces cerevisiae YJM1133, Saccharomyces cerevisiae YJM1450, Saccharomyces cerevisiae YJM1463, Saccharomyces cerevisiae YJM1478 Fungi UP000032931, UP000033161, UP000032964, UP000032965 767157026, 767179108, 767179709, 767180312 AJS40500.1, AJS53324.1, AJS53923.1, AJS54522.1 528 534 yes 2373235 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 660064, 1635285, 1635287 Methermicoccus shengliensis, Euryarchaeota archaeon 55_53, Methanosarcinales archeaon 56_1174 Archaea UP000056382, UP000065727 757132607 WP_042686869.1 A0A101DWF4, A0A101F3T0 A0A101DWF4_9EURY, A0A101F3T0_9EURY 340 343 no 2373236 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1334442 Cryptococcus gattii 2001/935-1 Fungi UP000053019 757392033 KIR97338.1 514 514 yes 2373237 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 697581 Thermofilum sp. 1505 Archaea 742685023 AJB41303.1 327 334 no 2373238 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 27457 Bactrocera dorsalis Invertebrates 751789284 XP_011204142.1 477 478 yes 2373239 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 994086 Hydnomerulius pinastri MD-312 Fungi UP000053820 749894768 KIJ62516.1 510 510 yes 2373240 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1579378 archaeon GW2011_AR20 Archaea UP000031765 751479768 AJF62320.1 A0A0B5HK22 A0A0B5HK22_9ARCH 325 328 no 2373241 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 913774 Oidiodendron maius Zn Fungi UP000054321 751754433 KIN02610.1 436 447 yes 2373242 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 51022 Ancylostoma duodenale Invertebrates UP000054047 748356678 KIH49924.1 136 137 no 2373243 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294375 Saccharomyces cerevisiae YJM1447 Fungi UP000032943 766121498 AJR51428.1 423 425 yes 2373244 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 930992 Suillus luteus UH-Slu-Lm8-n1 Fungi UP000054485 750998413 KIK40651.1 505 505 yes 2373245 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294362 Saccharomyces cerevisiae YJM1399 Fungi UP000033193 765938571 AJR49011.1 423 425 yes 2373246 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 215243 Exophiala oligosperma Fungi UP000053342 759262942 KIW39468.1 436 445 yes 2373247 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 51022 Ancylostoma duodenale Invertebrates UP000054047 748348942 KIH48669.1 135 137 no 2373248 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 946122 Amanita muscaria Koide BX008 Fungi UP000054549 751172530 KIL58577.1 501 502 yes 2373249 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294368 Saccharomyces cerevisiae YJM1418 Fungi UP000032967 767176706 AJS50932.1 528 534 yes 2373250 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 990650 Sphaerobolus stellatus SS14 Fungi UP000054279 749867041 KIJ37344.1 201 201 no 2373251 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294358 Saccharomyces cerevisiae YJM1386 Fungi UP000033194 767173766 AJS48002.1 528 534 yes 2373252 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 51022 Ancylostoma duodenale Invertebrates UP000054047 748345657 KIH48304.1 153 153 no 2373253 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 215243 Exophiala oligosperma Fungi UP000053342 759265490 KIW42012.1 573 573 yes 2373254 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294380 Saccharomyces cerevisiae YJM1478 Fungi UP000032965 766205684 AJR52376.1 423 425 yes 2373255 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 51022 Ancylostoma duodenale Invertebrates UP000054047 748346741 KIH48420.1 159 159 no 2373256 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 6265 Toxocara canis Invertebrates UP000031036 734544028 KHN72902.1 399 447 yes 2373257 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1442368 Fonsecaea pedrosoi CBS 271.37 Fungi UP000053029 915107318, 759306646 KIW83050.1 XP_013286858.1 576 576 yes 2373258 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 90675 Camelina sativa Plants 727426023, 727426025, 727426027 XP_010458072.1, XP_010458080.1, XP_010458087.1 446 458 yes 2373259 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 58291 Rhizopus microsporus Fungi UP000054919 729705623 118 119 no 2373260 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1036808 Scleroderma citrinum Foug A Fungi UP000053989 751714102 KIM63122.1 525 527 yes 2373261 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1410606 ammonia-oxidizing marine archaeon V2 Archaea UP000030944 851204714, 742121492 AJA92498.1 WP_048106133.1 A0A0A7V0U3 A0A0A7V0U3_9ARCH 332 334 no 2373262 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1579370 archaeon GW2011_AR10 Archaea UP000031777 751385698 AJF60778.1 A0A0B5HUF5 A0A0B5HUF5_9ARCH 329 332 no 2373263 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1442370 Cladophialophora bantiana CBS 173.52 Fungi UP000053789 759311662 KIW88024.1 441 448 yes 2373264 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1427455 Kluyveromyces dobzhanskii CBS 2104 Fungi UP000031516 748548285 592 593 yes 2373265 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1276141 Metarhizium brunneum ARSEF 3297 Fungi UP000031181 743646527 KID77645.1 530 530 yes 2373266 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579373 archaeon GW2011_AR15 Archaea UP000031776 751386050 AJF61129.1 A0A0B5HZ91 A0A0B5HZ91_9ARCH 87 95 no 2373267 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1442370 Cladophialophora bantiana CBS 173.52 Fungi UP000053789 759318308 KIW94655.1 576 576 yes 2373268 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 930992 Suillus luteus UH-Slu-Lm8-n1 Fungi UP000054485 750997134 KIK39420.1 522 524 no 2373269 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 745531 Phlebiopsis gigantea 11061_1 CR5-6 Fungi UP000053257 754370937 KIP03700.1 461 461 yes 2373270 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294340, 1294372 Saccharomyces cerevisiae YJM1248, Saccharomyces cerevisiae YJM1439 Fungi UP000032945, UP000033182 765705855, 766087756 AJR44632.1, AJR50863.1 423 425 yes 2373271 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 348802 Exophiala xenobiotica Fungi UP000054342 915156082, 759274635 KIW51143.1 XP_013311727.1 559 559 yes 2373272 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579373 archaeon GW2011_AR15 Archaea UP000031776 751385832 AJF60911.1 A0A0B5HKV1 A0A0B5HKV1_9ARCH 212 218 no 2373273 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1296112 Cryptococcus gattii Ru294 Fungi UP000053919 757347026 KIR52893.1 514 514 yes 2373274 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1130284 DHVE3 group archaeon JGI 0000106-F11 Archaea 756977771 WP_042665882.1 284 287 no 2373275 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6265 Toxocara canis Invertebrates UP000031036 734546422 KHN74911.1 332 338 no 2373276 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1296109 Cryptococcus gattii CA1280 Fungi UP000053819 757339872 KIR45818.1 A0A0D0UBZ8 A0A0D0UBZ8_CRYGA 516 516 yes 2373277 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 944289 Gymnopus luxurians FD-317 M1 Fungi UP000053593 751022449 KIK64153.1 525 525 no 2373278 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4182 Sesamum indicum Plants 747099914, 747099916 XP_011098024.1, XP_011098025.1 482 482 yes 2373279 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1442368 Fonsecaea pedrosoi CBS 271.37 Fungi UP000053029 915066529, 759300715 KIW77123.1 XP_013280931.1 438 446 yes 2373280 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 885580 Fukomys damarensis Rodents UP000028990 731194705 XP_010632955.1 453 471 yes 2373281 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 4182 Sesamum indicum Plants 747070943, 747070945 XP_011082319.1, XP_011082320.1 450 452 yes 2373282 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 3848 Glycine soja Plants UP000053555 734387676 KHN25439.1 379 381 no 2373283 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3555 Beta vulgaris subsp. vulgaris Plants UP000035740 731359777, 731359779, 870848654 KMT00943.1 XP_010691460.1, XP_010691461.1 509 509 yes 2373284 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1016849 Exophiala sp. SST-2011 Fungi UP000053599 759205975 KIV83394.1 432 444 yes 2373285 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579365 archaeon GW2011_AR3 Archaea 735012356 KHO46428.1 A0A0B3A2H1 A0A0B3A2H1_9ARCH 83 84 no 2373286 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 686832 Hebeloma cylindrosporum h7 Fungi UP000053424 751694343 KIM44325.1 539 539 yes 2373287 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 945553 Hypholoma sublateritium FD-334 SS-4 Fungi UP000054270 763727097 KJA24516.1 510 515 no 2373288 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1531966 Torrubiella hemipterigena Fungi UP000039046 729190900 455 458 yes 2373289 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28588 Bactrocera cucurbitae Invertebrates 751440222 XP_011188517.1 454 465 yes 2373290 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5601 Capronia semiimmersa Fungi UP000054266 759286700 KIW63195.1 436 447 yes 2373291 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 27457 Bactrocera dorsalis Invertebrates 751783927, 751783929, 751783931, 751783933, 751783935, 751783937, 751783939, 751783941 XP_011201232.1, XP_011201233.1, XP_011201234.1, XP_011201235.1, XP_011201236.1, XP_011201237.1, XP_011201238.1, XP_011201239.1 449 464 yes 2373292 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294361, 1294387 Saccharomyces cerevisiae YJM1389, Saccharomyces cerevisiae YJM1592 Fungi UP000033195, UP000032962 767174669, 767183362 AJS48902.1, AJS56581.1 528 534 yes 2373293 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 58291 Rhizopus microsporus Fungi UP000054919 729707793 390 390 no 2373294 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 58291 Rhizopus microsporus Fungi UP000054919 729707792 118 119 no 2373295 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579364 archaeon GW2011_AR1 Archaea 735010899 KHO45004.1 A0A0B3A8L6 A0A0B3A8L6_9ARCH 197 212 no 2373296 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579375 archaeon GW2011_AR17 Archaea 735017896 KHO51845.1 A0A0B3ANH2 A0A0B3ANH2_9ARCH 82 82 no 2373297 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1462419 Candidatus Iainarchaeum andersonii Archaea 754493957 WP_041910852.1 329 336 no 2373298 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1531966 Torrubiella hemipterigena Fungi UP000039046 729187398 520 520 yes 2373299 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1427455 Kluyveromyces dobzhanskii CBS 2104 Fungi UP000031516 748545865 301 303 yes 2373300 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 40199 Gibberella avenacea Fungi 751348024 KIL85746.1 535 535 yes 2373301 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 933852 Sebacina vermifera MAFF 305830 Fungi UP000054097 751680971 KIM31128.1 497 498 yes 2373302 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1296104, 1296101, 1296106, 1296110 Cryptococcus gattii 99/473, Cryptococcus gattii CBS 10090, Cryptococcus gattii LA55, Cryptococcus gattii Ram5 Fungi UP000054096, UP000054439, UP000053189, UP000053392 761937030, 757385272, 757319231, 757332773 KIY57820.1, KIR90603.1, KIR25344.1, KIR38808.1 514 514 yes 2373303 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 75702 Populus euphratica Plants 743931670, 743931672 XP_011010116.1, XP_011010117.1 458 460 yes 2373304 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 121 163 no 2373305 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 664439 Paxillus involutus ATCC 200175 Fungi UP000053647 749844795 KIJ19653.1 98 98 no 2373306 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1577791 Methanomassiliicoccales archaeon Mpt1 Archaea UP000030787 851215493, 731480897 AIZ56076.1 WP_048111406.1 A0A0A7LEZ5 A0A0A7LEZ5_9EURY 329 329 no 2373307 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1095629 Laccaria amethystina LaAM-08-1 Fungi UP000054477 750942624 KIK00574.1 510 510 yes 2373308 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 13686 Solenopsis invicta Invertebrates UP000006539 751237007, 751237009, 751237011 XP_011172366.1, XP_011172367.1, XP_011172368.1 407 410 yes 2373309 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9837 Camelus bactrianus Mammals 743725078, 743725080 XP_010956490.1, XP_010956491.1 346 363 yes 2373310 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294352, 1294369 Saccharomyces cerevisiae YJM1342, Saccharomyces cerevisiae YJM1419 Fungi UP000033185, UP000033181 767171881, 767177010 AJS46196.1, AJS51235.1 528 534 yes 2373311 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1128425 Fistulina hepatica ATCC 64428 Fungi UP000054144 761924497 KIY45847.1 498 502 no 2373312 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579372 archaeon GW2011_AR13 Archaea 735016464 KHO50471.1 A0A0B3APT7 A0A0B3APT7_9ARCH 96 98 no 2373313 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 61180 Oesophagostomum dentatum Invertebrates UP000053660 732861841 KHJ86547.1 283 327 no 2373314 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 61180 Oesophagostomum dentatum Invertebrates UP000053660 732803374 KHJ81748.1 101 103 no 2373315 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 765257 Pisolithus microcarpus 441 Fungi UP000054018 750960280 KIK17230.1 504 507 yes 2373316 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 215358 Larimichthys crocea Vertebrates UP000054355 734614794, 808873956 KKF23166.1 XP_010734969.1 417 426 yes 2373317 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294365, 1294385 Saccharomyces cerevisiae YJM1402, Saccharomyces cerevisiae YJM1573 Fungi UP000033191, UP000032966 765939086, 766281847 AJR49523.1, AJR53263.1 423 425 yes 2373318 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 52586 Erysiphe necator Fungi UP000030854 730186945 KHJ36269.1 446 451 yes 2373319 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 2205 Methanomicrobium mobile Archaea 757151132 WP_042705324.1 349 352 no 2373320 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29729 Gossypium arboreum Plants UP000032142 728807896 KHF97888.1 484 567 yes 2373321 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29172 Dictyocaulus viviparus Invertebrates UP000053766 768193180 KJH49179.1 460 462 yes 2373322 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294375 Saccharomyces cerevisiae YJM1447 Fungi UP000032943 767178821 AJS53038.1 528 534 yes 2373323 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1314674 Cylindrobasidium torrendii FP15055 ss-10 Fungi UP000054007 761949396 KIY69086.1 483 483 yes 2373324 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 90675 Camelina sativa Plants 727592493 XP_010469297.1 489 489 yes 2373325 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294319 Saccharomyces cerevisiae YJM682 Fungi UP000032949 767040712 AJS36000.1 528 534 yes 2373326 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 221 222 no 2373327 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579366 archaeon GW2011_AR4 Archaea 735012803 KHO46868.1 A0A0B3A3L9 A0A0B3A3L9_9ARCH 206 229 no 2373328 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1108050 Rhizoctonia solani AG-1 IB Fungi UP000012065 751838624 526 532 yes 2373329 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 29760 Vitis vinifera Plants UP000009183 UP000009183 731391231 XP_010650687.1 413 416 no 2373330 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294355 Saccharomyces cerevisiae YJM1381 Fungi UP000033179 767172856 AJS47095.1 528 534 yes 2373331 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 420 434 yes 2373332 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 90675 Camelina sativa Plants 727460850 XP_010512228.1 489 489 yes 2373333 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 68888 Trichuris suis Invertebrates UP000030764 730378553 KHJ49395.1 429 434 no 2373334 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1472165 Talaromyces cellulolyticus Fungi UP000053095 748556041 551 551 yes 2373335 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1095629 Laccaria amethystina LaAM-08-1 Fungi UP000054477 750950688 KIK08558.1 425 426 yes 2373336 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1051891 Tulasnella calospora MUT 4182 Fungi UP000054248 752367517 KIO25328.1 111 122 no 2373337 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 145388 Monoraphidium neglectum Plants UP000054498 761968717 KIY99878.1 520 520 no 2373338 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 913322 candidate division pMC2A384 archaeon SCGC AAA252-I15 Archaea 754482269 WP_041899538.1 221 221 no 2373339 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 990650 Sphaerobolus stellatus SS14 Fungi UP000054279 749887173 KIJ56491.1 177 177 no 2373340 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 994086 Hydnomerulius pinastri MD-312 Fungi UP000053820 749902869 KIJ70334.1 533 535 no 2373341 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 664439 Paxillus involutus ATCC 200175 Fungi UP000053647 749845158 KIJ19975.1 523 524 no 2373342 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294377 Saccharomyces cerevisiae YJM1460 Fungi UP000033170 767179408 AJS53623.1 528 534 yes 2373343 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 52644 Haliaeetus leucocephalus Vertebrates 729767252 XP_010580801.1 475 476 yes 2373344 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 103372 Acromyrmex echinatior Invertebrates UP000007755 746865292 XP_011063677.1 462 472 yes 2373345 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 5601 Capronia semiimmersa Fungi UP000054266 759295583 KIW71997.1 579 579 yes 2373346 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 75702 Populus euphratica Plants 743810467 XP_011018752.1 496 496 yes 2373347 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 933852 Sebacina vermifera MAFF 305830 Fungi UP000054097 751671721 KIM21963.1 628 634 no 2373348 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1051891 Tulasnella calospora MUT 4182 Fungi UP000054248 752373317 KIO31050.1 527 532 no 2373349 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1276143 Metarhizium majus ARSEF 297 Fungi UP000031176 743671418 KID98354.1 529 529 yes 2373350 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1410327 Acytostelium subglobosum LB1 Invertebrates 831766791, 735852533 XP_012751901.1 570 578 yes 2373351 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8010 Esox lucius Vertebrates 742165062 XP_010884128.1 496 501 yes 2373352 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29730 Gossypium raimondii Plants UP000032304 823161331, 823161333, 763765493 KJB32747.1 XP_012480536.1, XP_012480537.1 458 464 yes 2373353 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3848 Glycine soja Plants UP000053555 734427401 KHN44176.1 378 441 yes 2373354 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 90675 Camelina sativa Plants 727540837 XP_010444039.1 444 451 yes 2373355 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 58291 Rhizopus microsporus Fungi UP000054919 729711952 427 429 yes 2373356 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 91626 Mucor ambiguus Fungi UP000053815 758354727 475 704 yes 2373357 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1379386 Thaumarchaeota archaeon JGI OTU-3 Archaea 756974698 WP_042662982.1 328 333 no 2373358 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1296111 Cryptococcus gattii CA1873 Fungi UP000053800 757353320 KIR59153.1 516 516 yes 2373359 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1348249 Methanobrevibacter boviskoreani Archaea 750400233 WP_040682139.1 334 336 no 2373360 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 35722 Parasitella parasitica Fungi UP000054107 758357776 556 556 yes 2373361 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3848 Glycine soja Plants UP000053555 734379283 KHN22447.1 485 485 yes 2373362 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1603295 fungal sp. No.11243 Fungi UP000054361 752280662 557 557 yes 2373363 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1245769 Lachancea lanzarotensis Fungi UP000054304 761760395 417 419 yes 2373364 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 6265 Toxocara canis Invertebrates UP000031036 734523163 KHN71325.1 127 127 no 2373365 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 91928 Exophiala spinifera Fungi UP000053328 759237150 KIW14095.1 434 444 yes 2373366 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1296103, 1296108 Cryptococcus gattii EJB2, Cryptococcus gattii NT-10 Fungi UP000054272, UP000053389 757373816, 765280077 KIR79392.1, KJE02624.1 513 521 no 2373367 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 91928 Exophiala spinifera Fungi UP000053328 759243861 KIW20801.1 573 573 yes 2373368 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294335, 1294336, 1294344 Saccharomyces cerevisiae YJM1199, Saccharomyces cerevisiae YJM1202, Saccharomyces cerevisiae YJM1304 Fungi UP000032986, UP000032976, UP000032924 767157632, 767157935, 767167288 AJS41104.1, AJS41406.1, AJS43785.1 528 534 yes 2373369 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294363, 1294381 Saccharomyces cerevisiae YJM1400, Saccharomyces cerevisiae YJM1479 Fungi UP000033168, UP000032982 767175200, 767180608 AJS49431.1, AJS54817.1 528 534 yes 2373370 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294340, 1294372, 1294305, 1294317 Saccharomyces cerevisiae YJM1248, Saccharomyces cerevisiae YJM1439, Saccharomyces cerevisiae YJM195, Saccharomyces cerevisiae YJM627 Fungi UP000032945, UP000033182, UP000032947, UP000032939 767166112, 767177921, 767009456, 767040045 AJS42613.1, AJS52143.1, AJS30657.1, AJS35402.1 528 534 yes 2373371 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 40199 Gibberella avenacea Fungi 751346143 KIL83865.1 472 478 yes 2373372 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 71518 Methanocorpusculum bavaricum Archaea 757142390 WP_042696623.1 316 316 no 2373373 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1081103 Metarhizium album ARSEF 1941 Fungi UP000030816 734658401 KHN95468.1 521 521 yes 2373374 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 870435 Pisolithus tinctorius Marx 270 Fungi UP000054217 752353990 KIO13037.1 524 528 no 2373375 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 91626 Mucor ambiguus Fungi UP000053815 758347175 456 463 yes 2373376 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 52586 Erysiphe necator Fungi UP000030854 730177102 KHJ32051.1 675 694 yes 2373377 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1296109, 1296111 Cryptococcus gattii CA1280, Cryptococcus gattii CA1873 Fungi UP000053819, UP000053800 757339306, 757363182 KIR45256.1, KIR68998.1 A0A0D0VCI9 A0A0D0VCI9_CRYGA 516 522 no 2373378 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294378 Saccharomyces cerevisiae YJM1463 Fungi UP000032964 766143757 AJR51993.1 423 425 yes 2373379 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294308 Saccharomyces cerevisiae YJM270 Fungi UP000032951 767010355 AJS31553.1 528 534 yes 2373380 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294353 Saccharomyces cerevisiae YJM1355 Fungi UP000033160 767172254 AJS46495.1 528 534 yes 2373381 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 237631 Ustilago maydis 521 Fungi UP000000561 UP000000561 758976632, 757947743 KIS70209.1 XP_011388369.1 670 671 yes 2373382 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294345 Saccharomyces cerevisiae YJM1307 Fungi UP000033192 767167944 AJS44088.1 528 534 yes 2373383 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1296105 Cryptococcus gattii IND107 Fungi UP000054399 757379469 KIR84825.1 514 514 yes 2373384 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1276143 Metarhizium majus ARSEF 297 Fungi UP000031176 743677047 KIE03960.1 458 857 yes 2373385 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579377 archaeon GW2011_AR19 Archaea 735021624 KHO55433.1 A0A0B3ASG1 A0A0B3ASG1_9ARCH 244 253 no 2373386 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294363, 1294381 Saccharomyces cerevisiae YJM1400, Saccharomyces cerevisiae YJM1479 Fungi UP000033168, UP000032982 765938708, 766238360 AJR49147.1, AJR52565.1 423 425 yes 2373387 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 400682 Amphimedon queenslandica Invertebrates UP000007879 761904270 XP_003384247.2 333 334 yes 2373388 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28532 Cleome hassleriana Plants 729454743, 729454746 XP_010524170.1, XP_010524171.1 504 505 yes 2373389 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294357 Saccharomyces cerevisiae YJM1385 Fungi UP000033175 767173464 AJS47701.1 528 534 yes 2373390 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294348 Saccharomyces cerevisiae YJM1332 Fungi UP000033190 767170666 AJS44985.1 528 534 yes 2373391 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1292971, 1294334, 1294341, 1294313 Saccharomyces cerevisiae YJM1083, Saccharomyces cerevisiae YJM1190, Saccharomyces cerevisiae YJM1250, Saccharomyces cerevisiae YJM470 Fungi UP000032925, UP000032968, UP000032935, UP000032921 767156419, 767157329, 767166383, 767032828 AJS39895.1, AJS40802.1, AJS42883.1, AJS34199.1 528 534 yes 2373392 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1410327 Acytostelium subglobosum LB1 Invertebrates 831756980, 735849717 XP_012748888.1 463 468 yes 2373393 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 138 142 no 2373394 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9606 Homo sapiens Primates UP000005640 UP000005640 767902798, 767902800 XP_011539168.1, XP_011539169.1 295 296 no 2373395 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1245769 Lachancea lanzarotensis Fungi UP000054304 761760697 569 572 yes 2373396 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 28532 Cleome hassleriana Plants 729291609 XP_010519544.1 444 455 yes 2373397 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 765257 Pisolithus microcarpus 441 Fungi UP000054018 750973974 KIK30775.1 524 526 no 2373398 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1296112 Cryptococcus gattii Ru294 Fungi UP000053919 757345615 KIR51490.1 513 521 no 2373399 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579372 archaeon GW2011_AR13 Archaea 735017478 KHO51458.1 A0A0B3AGB7 A0A0B3AGB7_9ARCH 197 210 no 2373400 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 8208 Notothenia coriiceps Vertebrates 736253152 XP_010788786.1 245 248 no 2373401 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 930991 Paxillus rubicundulus Ve08.2h10 Fungi UP000054538 751041144 KIK77868.1 511 511 yes 2373402 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 8090 Oryzias latipes Vertebrates UP000001038 765153859 XP_011487068.1 463 463 yes 2373403 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1592728, 1622207 Haloarcula sp. CBA1115, Haloarcula sp. k1 Archaea UP000031628 910232688, 749701957 AJF26751.1 WP_050037863.1 A0A0B5GQA9, A0A162FUD3 A0A0B5GQA9_9EURY, A0A162FUD3_9EURY 347 348 no 2373404 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 90675 Camelina sativa Plants 727437642 XP_010500149.1 489 489 yes 2373405 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294360 Saccharomyces cerevisiae YJM1388 Fungi UP000033165 767174372 AJS48606.1 528 534 yes 2373406 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1442371 Fonsecaea multimorphosa CBS 102226 Fungi UP000053411 761336410 KIX97462.1 440 446 yes 2373407 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 326594 Ceratosolen solmsi marchali Invertebrates 766917956 XP_011495599.1 435 435 yes 2373408 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 253628 Ochroconis gallopava Fungi UP000053259 759224188, 759224189 KIW01187.1, KIW01188.1 A0A0D1YJZ4 A0A0D1YJZ4_9PEZI 325 332 yes 2373409 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1108050 Rhizoctonia solani AG-1 IB Fungi UP000012065 751837245 486 491 no 2373410 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 51953 Elaeis guineensis Plants 743815069 XP_010930233.1 503 503 yes 2373411 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579368 archaeon GW2011_AR6 Archaea 735015936 KHO49955.1 A0A0B3AI70 A0A0B3AI70_9ARCH 208 220 no 2373412 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1036808 Scleroderma citrinum Foug A Fungi UP000053989 751718909 KIM67903.1 433 436 yes 2373413 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 944288 Plicaturopsis crispa FD-325 SS-3 Fungi UP000053263 749759847 KII84822.1 496 497 yes 2373414 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 212818 Exophiala mesophila Fungi UP000054302 759216845 KIV94183.1 544 544 yes 2373415 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294360, 1294361, 1294377, 1294387 Saccharomyces cerevisiae YJM1388, Saccharomyces cerevisiae YJM1389, Saccharomyces cerevisiae YJM1460, Saccharomyces cerevisiae YJM1592 Fungi UP000033165, UP000033195, UP000033170, UP000032962 765923544, 765938378, 766121878, 766282232 AJR48627.1, AJR48819.1, AJR51806.1, AJR53646.1 423 425 yes 2373416 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 132908 Pteropus vampyrus Mammals 759119125 XP_011358165.1 412 432 yes 2373417 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 132908 Pteropus vampyrus Mammals 759119122 XP_011358164.1 430 440 yes 2373418 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294362 Saccharomyces cerevisiae YJM1399 Fungi UP000033193 767174971 AJS49203.1 528 534 yes 2373419 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1314674 Cylindrobasidium torrendii FP15055 ss-10 Fungi UP000054007 761945659 KIY65449.1 506 509 no 2373420 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 9837 Camelus bactrianus Mammals 743696421 XP_010947192.1 261 261 no 2373421 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1296105 Cryptococcus gattii IND107 Fungi UP000054399 757378471 KIR83832.1 514 522 no 2373422 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 52644 Haliaeetus leucocephalus Vertebrates 729750700 XP_010571932.1 397 406 yes 2373423 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1296117 Cryptococcus gattii MMRL2647 Fungi UP000053522 757325398 KIR31460.1 514 514 yes 2373424 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 43346 Bison bison bison Mammals 742208286 XP_010859626.1 429 438 yes 2373425 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1579371 archaeon GW2011_AR11 Archaea 735017485 KHO51464.1 A0A0B3ARW4 A0A0B3ARW4_9ARCH 208 237 no 2373426 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 190977 Methanobrevibacter wolinii Archaea 757153102 WP_042707214.1 335 336 no 2373427 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 946122 Amanita muscaria Koide BX008 Fungi UP000054549 751182397 KIL68339.1 495 500 no 2373428 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 569365 Cladophialophora sp. HB-2008 Fungi UP000054466 759249166 KIW25833.1 439 446 yes 2373429 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 669202 Thelohanellus kitauei Invertebrates UP000031668 749721476 KII68718.1 270 385 no 2373430 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 944289 Gymnopus luxurians FD-317 M1 Fungi UP000053593 751023805 KIK65505.1 555 559 no 2373431 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 104421 Camponotus floridanus Invertebrates UP000000311 752897170 XP_011266878.1 404 409 yes 2373432 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 913774 Oidiodendron maius Zn Fungi UP000054321 751749228 KIM97412.1 556 556 yes 2373433 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 3555 Beta vulgaris subsp. vulgaris Plants UP000035740 731328706, 870862119 KMT13354.1 XP_010675198.1 459 464 yes 2373434 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 947044 Saccharomyces cerevisiae YJM428 Fungi UP000032981 767019433 AJS32752.1 528 534 yes 2373435 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 870435 Pisolithus tinctorius Marx 270 Fungi UP000054217 752346511 KIO05577.1 445 463 yes 2373436 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9785 Loxodonta africana Mammals UP000007646 731501212 XP_010594790.1 420 438 yes 2373437 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1294343, 1294365, 1294371, 1294385 Saccharomyces cerevisiae YJM1273, Saccharomyces cerevisiae YJM1402, Saccharomyces cerevisiae YJM1434, Saccharomyces cerevisiae YJM1573 Fungi UP000032971, UP000033191, UP000033176, UP000032966 767166985, 767175798, 767177618, 767181213 AJS43483.1, AJS50027.1, AJS51841.1, AJS55984.1 528 534 yes 2373438 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 945553 Hypholoma sublateritium FD-334 SS-4 Fungi UP000054270 763718533 KJA16045.1 559 561 yes 2373439 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 145388 Monoraphidium neglectum Plants UP000054498 761965648 KIY97597.1 356 357 no 2373440 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1291519, 1291518, 1276141 Metarhizium anisopliae BRIP 53284, Metarhizium anisopliae BRIP 53293, Metarhizium brunneum ARSEF 3297 Fungi UP000054525, UP000054544, UP000031181 770406194, 770395609, 743646661 KJK91079.1, KJK81583.1, KID77727.1 452 454 yes 2373441 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1292971 Saccharomyces cerevisiae YJM1083 Fungi UP000032925 765704117 AJR42903.1 423 425 yes 2373442 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1276136 Metarhizium guizhouense ARSEF 977 Fungi UP000031192 743658228 KID85544.1 529 529 yes 2373443 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1442371 Fonsecaea multimorphosa CBS 102226 Fungi UP000053411 761336685 KIX97725.1 580 580 yes 2373444 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 29172 Dictyocaulus viviparus Invertebrates UP000053766 768197458 KJH53102.1 391 392 yes 2373445 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 745531 Phlebiopsis gigantea 11061_1 CR5-6 Fungi UP000053257 754374351 KIP07015.1 533 535 no 2373446 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 765440 Piloderma croceum F 1598 Fungi UP000054166 751742358 KIM90632.1 531 535 no 2373447 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 686832 Hebeloma cylindrosporum h7 Fungi UP000053424 751695855 KIM45834.1 481 497 no 2373448 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 569365 Cladophialophora sp. HB-2008 Fungi UP000054466 759249571 KIW26238.1 578 578 yes 2373449 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 104421 Camponotus floridanus Invertebrates UP000000311 752897168 XP_011266877.1 408 413 yes 2373450 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 1353246 Thaumarchaeota archaeon MY2 Archaea 757130308 WP_042684582.1 319 331 no 2373451 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 13686 Solenopsis invicta Invertebrates UP000006539 751207266 XP_011156190.1 463 472 yes 2373452 Diphthamide biosynthesis family (Dph2) 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 1121 Diphthamide biosynthesis 408 Diphthamide biosynthesis family (Dph2) IEA 9838 Camelus dromedarius Mammals 744561002 XP_010977196.1 346 363 yes 2373453 uncharacterized Radical SAM 3-amino-3-carboxypropyl Radical Forming extended sequence 32 Radical SAM 3-amino-3-carboxypropyl Radical Forming IEA 29729 Gossypium arboreum Plants UP000032142 728837908 KHG17351.1 369 400 no