efd_id common_name superfamily_id superfamily superfamily_evidence_code subgroup_id subgroup family_id family family_evidence_code taxon_ids species type_of_life patric_cid phylogenetic_reference_proteome uniprot_reference_proteome reaction_scheme_id reaction_scheme_name gi genbank_accession_number refseq_accession_number uniprot swissprot swissprot_name trembl microbes_online the_seed length_domain length_full pdb_ids pdb_homologues ec number conserves all functional residues 395637 Phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) CFM 155892, 190650 Caulobacter vibrioides, Caulobacter crescentus CB15 Bacteria UP000053705, UP000001816 210061057, 210061056 Q9A6Q5 THIC_CAUCR Phosphomethylpyrimidine synthase 5849372, 98846 611 612 3EPN, 3EPO, 4S2A, 3EPM yes 396475 Phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 190650, 155892, 565050 Caulobacter crescentus CB15, Caulobacter vibrioides, Caulobacter crescentus NA1000 Bacteria UP000001816, UP000053705, UP000001364 16126272, 499222355, 221235046, 220964218, 13423504, 254784156, 210061061, 210061060, 210061059, 210061058, 24638281 ACL95574.1, AAK24004.1 NP_420836.1, WP_010919895.1, YP_002517482.1 B8GX84, Q9A6Q5 THIC_CAUCN, THIC_CAUCR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089}, Phosphomethylpyrimidine synthase 5849372, 98846 fig|190650.1.peg.2016, fig|565050.3.peg.2067 612 612 3EPM, 3EPN, 3EPO, 4S2A yes 430924 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 511145, 543, 562, 1358422, 1411691, 83333, 941323, 758831, 1010817, 1245474, 1333537, 1412834, 679895, 1435461, 1444153, 1444123, 1444210, 1444257, 1444282, 1444256, 1444115, 1444226, 1444255, 1444128, 1444254, 1444196, 1444142, 1444209, 1444043, 1444166, 1444108, 1444185, 1444238, 1444127, 1444045, 1444267, 1444184, 1444155, 1444237, 1444126, 1444208, 1444072, 1444182, 1444154, 1444124, 1444122, 1444180, 1444152, 1444069, 1444200, 1444096, 1444040, 1444121, 1444178, 1444095, 1446744, 1446765, 1446599, 1446583, 1446756, 1444280, 1444224, 1444222, 1444225, 1444167, 1444139, 1444093, 1438696, 1438691, 1438687, 1444244, 1444176, 1444064, 1444273, 1457300, 1446742, 1446766, 1446741, 1446584, 1446503, 1446608, 1446740, 1446737, 1446703, 1446760, 1446506, 1446504, 1446706, 1446700, 1446603, 1446605, 1446505, 1446743, 1444077, 1444049, 1444104, 1444190, 1444272, 1405294, 1331061, 758830, 758832, 1331064, 1280986, 1328448, 1281243, 1269003, 1268997, 1268985, 1268979, 1385755, 1335916, 1281193, 1281273, 1281254, 1281253, 1281247, 1281242, 1281239, 1281214, 1281208, 1281206, 1281204, 1281189, 1281179, 1281172, 1281147, 1281136, 1281127, 1281122, 1281097, 1281083, 1281058, 1281052, 1281051, 1281028, 1281019, 1280984, 1280969, 1331062, 1182729, 1182716, 1182715, 1182702, 1182703, 1182678, 1182668, 1181768, 1181767, 1181744, 1169352, 1169333, 1169320, 1116094, 1116095, 1116093, 1116181, 1116180, 1116162, 1116160, 1116161, 1116106, 1116107, 1116097, 1116092, 1116090, 1116102, 1116099, 1116184, 1116178, 1116191, 1116188, 1116187, 1116170, 1116169, 1116168, 1116167, 1116166, 1116165, 1116164, 1116176, 1116175, 1116174, 1116173, 1116172, 1116078, 1116077, 1116076, 1116074, 1116079, 1125646, 1125651, 1125650, 1125649, 1125648, 1125636, 1116101, 1116156, 1116157, 1116155, 1116045, 1116114, 1116027, 1116005, 1116104, 1116109, 1116004, 1116129, 1116177, 1116089, 1116121, 1116003, 1116037, 1116120, 1115998, 1116122, 1115997, 1115999, 1116140, 1116000, 1116133, 1116073, 1116153, 1116163, 1116001, 1116105, 1116011, 1116012, 1116014, 1116017, 1116018, 1116019, 1116020, 1116021, 1116026, 1116028, 1116029, 1116031, 1116034, 1116035, 1116134, 1090929, 1090930, 1227813, 1227814, 1274814, 1169397, 1169396, 1169388, 1169379, 1181743, 1182728, 1182700, 1169359, 1182738, 1182733, 1182730, 1182706, 1182688, 1182684, 1182658, 1005464, 1005462, 1005442, 1005567, 1005564, 1005562, 754081, 766166, 670896, 752788, 1165941, 1165940, 869694, 869691, 869690, 869688, 869687, 869680, 869679, 869677, 869675, 869671, 869670, 457401, 656413, 1167694, 1144303, 1090926, 566546, 595495, 868210, 868209, 868208, 868207, 868206, 868204, 868203, 868202, 868200, 868199, 868197, 868198, 868195, 868196, 868194, 868193, 868191, 868192, 868190, 868188, 868189, 868187, 868186, 868184, 868169, 868168, 868167, 868165, 868164, 868163, 868162, 868160, 868161, 656405, 670903, 754090, 754088, 754078, 754087, 754084, 1068608, 1050617, 696406, 556266, 656408, 656414, 656372, 749539, 550687, 670890, 670894, 945434, 670892, 679202, 670888, 749540, 679205, 679206, 749538, 749533, 749544, 749548, 536056, 595496, 457400, 344601, 340185, 316385, 331112, 1400023, 1411645, 1432548, 1403831, 1246623, 475609, 1110693, 585395, 409438, 585034, 316407 Escherichia coli str. K-12 substr. MG1655, Escherichia coli, Escherichia coli PCN061, Escherichia coli GM4792, Escherichia coli K-12, Escherichia coli VR50, Escherichia coli ECC-1470, Escherichia coli C691-71 (14b), Escherichia coli ER2796, Escherichia coli NCTC 50110, Escherichia coli FAP1, Escherichia coli BW25113, Escherichia coli KLY, Escherichia coli 2-222-05_S3_C2, Escherichia coli 2-222-05_S3_C1, Escherichia coli 2-474-04_S4_C1, Escherichia coli 6-537-08_S4_C2, Escherichia coli 6-319-05_S4_C3, Escherichia coli 6-319-05_S4_C2, Escherichia coli 6-319-05_S1_C3, Escherichia coli 6-175-07_S4_C1, Escherichia coli 6-175-07_S4_C2, Escherichia coli 5-172-05_S3_C1, Escherichia coli 4-203-08_S4_C2, Escherichia coli 4-203-08_S3_C3, Escherichia coli 3-475-03_S3_C1, Escherichia coli 2-460-02_S4_C1, Escherichia coli 2-427-07_S1_C1, Escherichia coli 3-073-06_S3_C2, Escherichia coli 3-020-07_S1_C3, Escherichia coli 2-474-04_S3_C3, Escherichia coli 2-474-04_S4_C2, Escherichia coli 2-474-04_S3_C1, Escherichia coli 2-474-04_S1_C1, Escherichia coli 2-460-02_S4_C3, Escherichia coli 2-460-02_S3_C3, Escherichia coli 2-460-02_S3_C2, Escherichia coli 2-460-02_S4_C2, Escherichia coli 2-460-02_S3_C1, Escherichia coli 2-427-07_S4_C1, Escherichia coli 2-427-07_S1_C2, Escherichia coli 2-316-03_S3_C3, Escherichia coli 2-316-03_S3_C2, Escherichia coli 2-316-03_S3_C1, Escherichia coli 2-210-07_S3_C1, Escherichia coli 2-210-07_S3_C3, Escherichia coli 2-210-07_S3_C2, Escherichia coli 2-210-07_S1_C2, Escherichia coli 2-005-03_S4_C1, Escherichia coli 2-177-06_S1_C3, Escherichia coli 2-177-06_S1_C1, Escherichia coli 2-177-06_S3_C1, Escherichia coli 2-156-04_S3_C3, Escherichia coli 2-156-04_S1_C3, Escherichia coli O45:H2 str. 2010C-4211, Escherichia coli O91:H21 str. 2009C-3740, Escherichia coli O146:H21 str. 2010C-3325, Escherichia coli O145:H25 str. 07-3858, Escherichia coli O78:H12 str. 00-3279, Escherichia coli 4-203-08_S4_C3, Escherichia coli 3-373-03_S4_C1, Escherichia coli 3-105-05_S4_C1, Escherichia coli 3-475-03_S4_C1, Escherichia coli 3-105-05_S3_C2, Escherichia coli 3-105-05_S3_C1, Escherichia coli 2-011-08_S1_C3, Escherichia coli UCI 66, Escherichia coli UCI 53, Escherichia coli MGH 57, Escherichia coli 1-176-05_S4_C2, Escherichia coli 2-011-08_S3_C3, Escherichia coli 2-005-03_S1_C2, Escherichia coli 1-176-05_S4_C3, Escherichia coli 1728, Escherichia coli O45:H2 str. 2009C-4780, Escherichia coli O91:H21 str. 2009C-4646, Escherichia coli O45:H2 str. 2009C-3686, Escherichia coli O145:H28 str. 2009C-3292, Escherichia coli O103:H2 str. 2009C-3279, Escherichia coli O157:H16 str. 98-3133, Escherichia coli O45:H2 str. 01-3147, Escherichia coli O28ac:NM str. 02-3404, Escherichia coli O174:H21 str. 03-3269, Escherichia coli O79:H7 str. 06-3501, Escherichia coli O103:H25 str. 2010C-4529, Escherichia coli O103:H2 str. 2010C-4433, Escherichia coli O177:NM str. 2010C-4558, Escherichia coli O165:H25 str. 2010C-4874, Escherichia coli O153:H2 str. 2010C-5034, Escherichia coli O156:H25 str. 2011C-3602, Escherichia coli O103:H2 str. 2011C-3750, Escherichia coli O45:H2 str. 2010C-3876, Escherichia coli 1-110-08_S1_C2, Escherichia coli 1-110-08_S1_C1, Escherichia coli 1-110-08_S1_C3, Escherichia coli 1-110-08_S3_C3, Escherichia coli 1-110-08_S4_C3, Escherichia coli ATCC BAA-2215, Escherichia coli E1777, Escherichia coli ECA-727, Escherichia coli ECC-Z, Escherichia coli CE516, Escherichia coli HVH 36 (4-5675286), Escherichia coli BIDMC 37, Escherichia coli UMEA 3336-1, Escherichia coli 908658, Escherichia coli 908555, Escherichia coli 907710, Escherichia coli 907357, Escherichia coli C321.deltaA, Escherichia coli LY180, Escherichia coli UMEA 3150-1, Escherichia coli UMEA 3889-1, Escherichia coli UMEA 3609-1, Escherichia coli UMEA 3592-1, Escherichia coli UMEA 3355-1, Escherichia coli UMEA 3329-1, Escherichia coli UMEA 3317-1, Escherichia coli UMEA 3201-1, Escherichia coli UMEA 3180-1, Escherichia coli UMEA 3176-1, Escherichia coli UMEA 3174-1, Escherichia coli UMEA 3139-1, Escherichia coli UMEA 3065-1, Escherichia coli KOEGE 131 (358a), Escherichia coli HVH 221 (4-3136817), Escherichia coli HVH 209 (4-3062651), Escherichia coli HVH 200 (4-4449924), Escherichia coli HVH 195 (3-7155360), Escherichia coli HVH 164 (4-5953081), Escherichia coli HVH 150 (4-3258106), Escherichia coli HVH 121 (4-6877826), Escherichia coli HVH 115 (4-4465989), Escherichia coli HVH 115 (4-4465997), Escherichia coli HVH 91 (4-4638751), Escherichia coli HVH 82 (4-2209276), Escherichia coli HVH 33 (4-2174936), Escherichia coli HVH 18 (4-8589585), Escherichia coli E2265, Escherichia coli KTE155, Escherichia coli KTE132, Escherichia coli KTE130, Escherichia coli KTE103, Escherichia coli KTE107, Escherichia coli KTE71, Escherichia coli KTE61, Escherichia coli KTE222, Escherichia coli KTE221, Escherichia coli KTE198, Escherichia coli KTE34, Escherichia coli KTE14, Escherichia coli KTE35, Escherichia coli p0305293.6, Escherichia coli p0305293.7, Escherichia coli p0305293.5, Escherichia coli P0304816.5, Escherichia coli P0304816.4, Escherichia coli P0302308.14, Escherichia coli P0302308.12, Escherichia coli P0302308.13, Escherichia coli 178850, Escherichia coli 178200, Escherichia coli p0305293.9, Escherichia coli p0305293.4, Escherichia coli p0305293.2, Escherichia coli p0305293.15, Escherichia coli p0305293.11, Escherichia coli P0304816.8, Escherichia coli P0304816.2, Escherichia coli P0304816.15, Escherichia coli P0304816.12, Escherichia coli P0304816.11, Escherichia coli P0304777.9, Escherichia coli P0304777.8, Escherichia coli P0304777.7, Escherichia coli P0304777.5, Escherichia coli P0304777.4, Escherichia coli P0304777.3, Escherichia coli P0304777.2, Escherichia coli P0304777.15, Escherichia coli P0304777.14, Escherichia coli P0304777.13, Escherichia coli P0304777.12, Escherichia coli P0304777.11, Escherichia coli P0302293.9, Escherichia coli P0302293.8, Escherichia coli P0302293.6, Escherichia coli P0302293.3, Escherichia coli P0302293.10, Escherichia coli p0305293.14, Escherichia coli P0304799.3, Escherichia coli P0299483.3, Escherichia coli P0299483.2, Escherichia coli P0299483.1, Escherichia coli 2854350, Escherichia coli p0305293.13, Escherichia coli P0302308.4, Escherichia coli P0302308.5, Escherichia coli P0302308.3, Escherichia coli P0299438.10, Escherichia coli BCE011_MS-01, Escherichia coli 2866350, Escherichia coli 2730350, Escherichia coli 180200, Escherichia coli 179550, Escherichia coli 2729250, Escherichia coli 201600.1, Escherichia coli P0304816.1, Escherichia coli p0305293.1, Escherichia coli 2722950, Escherichia coli 174900, Escherichia coli BCE001_MS16, Escherichia coli 2720900, Escherichia coli Envira 10/1, Escherichia coli 2726800, Escherichia coli Envira 8/11, Escherichia coli Jurua 18/11, Escherichia coli MP020940.1, Escherichia coli Jurua 20/10, Escherichia coli MP021552.8, Escherichia coli P0302293.2, Escherichia coli P0302308.1, Escherichia coli P0304777.1, Escherichia coli ThroopD, Escherichia coli 180600, Escherichia coli 2749250, Escherichia coli 2756500, Escherichia coli 2770900, Escherichia coli 2788150, Escherichia coli 2850400, Escherichia coli 2850750, Escherichia coli 2853500, Escherichia coli 2860050, Escherichia coli 2865200, Escherichia coli 2866450, Escherichia coli 2866550, Escherichia coli 2867750, Escherichia coli 2872800, Escherichia coli 2875000, Escherichia coli MP021552.11, Escherichia coli O127:H27 str. C43/90, Escherichia coli ONT:H33 str. C48/93, Escherichia coli S17, Escherichia coli O08, Escherichia coli APEC O78, Escherichia coli KTE166, Escherichia coli KTE163, Escherichia coli KTE138, Escherichia coli KTE120, Escherichia coli KTE197, Escherichia coli KTE154, Escherichia coli KTE101, Escherichia coli KTE42, Escherichia coli KTE171, Escherichia coli KTE161, Escherichia coli KTE156, Escherichia coli KTE111, Escherichia coli KTE81, Escherichia coli KTE77, Escherichia coli KTE51, Escherichia coli 8.0569, Escherichia coli 8.0566, Escherichia coli 0.1288, Escherichia coli N1, Escherichia coli TW00353, Escherichia coli TW15901, Escherichia coli STEC_O31, Escherichia coli EPEC C342-62, Escherichia coli EPECa12, Escherichia coli 75, Escherichia coli O103:H2 str. CVM9450, Escherichia coli O103:H25 str. CVM9340, Escherichia coli B41, Escherichia coli 3.2303, Escherichia coli 2.4168, Escherichia coli 2.3916, Escherichia coli 4.0967, Escherichia coli 93.0624, Escherichia coli 3.2608, Escherichia coli 96.0497, Escherichia coli 1.2264, Escherichia coli 5.0588, Escherichia coli 97.0246, Escherichia sp. 4_1_40B, Escherichia coli H730, Escherichia coli O32:H37 str. P4, Escherichia coli J53, Escherichia coli W26, Escherichia coli W, Escherichia coli KO11, Escherichia coli DEC15E, Escherichia coli DEC15D, Escherichia coli DEC15C, Escherichia coli DEC15B, Escherichia coli DEC15A, Escherichia coli DEC14D, Escherichia coli DEC14C, Escherichia coli DEC14B, Escherichia coli DEC13E, Escherichia coli DEC13D, Escherichia coli DEC13B, Escherichia coli DEC13C, Escherichia coli DEC12E, Escherichia coli DEC13A, Escherichia coli DEC12D, Escherichia coli DEC12C, Escherichia coli DEC12A, Escherichia coli DEC12B, Escherichia coli DEC11E, Escherichia coli DEC11C, Escherichia coli DEC11D, Escherichia coli DEC11B, Escherichia coli DEC11A, Escherichia coli DEC10E, Escherichia coli DEC7E, Escherichia coli DEC7D, Escherichia coli DEC7C, Escherichia coli DEC7A, Escherichia coli DEC6E, Escherichia coli DEC6D, Escherichia coli DEC6C, Escherichia coli DEC6A, Escherichia coli DEC6B, Escherichia coli H494, Escherichia coli TX1999, Escherichia coli STEC_S1191, Escherichia coli STEC_H.1.8, Escherichia coli G58-1, Escherichia coli STEC_EH250, Escherichia coli STEC_B2F1, Escherichia coli XH140A, Escherichia coli UMNF18, Escherichia coli UMNK88, Shigella sp. D9, Escherichia coli H591, Escherichia coli H736, Escherichia coli E1167, Escherichia coli MS 117-3, Escherichia coli E482, Escherichia coli LT-68, Escherichia coli E128010, Escherichia coli EC4100B, Escherichia coli 3431, Escherichia coli MS 85-1, Escherichia coli 1827-70, Escherichia coli MS 146-1, Escherichia coli MS 124-1, Escherichia coli MS 119-7, Escherichia coli MS 116-1, Escherichia coli MS 84-1, Escherichia coli MS 175-1, Escherichia coli MS 196-1, Escherichia coli DH1, Escherichia coli BW2952, Escherichia sp. 1_1_43, Escherichia coli B171, Escherichia coli E22, Escherichia coli str. K-12 substr. DH10B, Escherichia coli HS, Escherichia coli D6-117.29, Escherichia coli IS9, Escherichia coli IS25, Escherichia coli str. K-12 substr. MC4100, Escherichia coli O10:K5(L):H4 str. ATCC 23506, Escherichia coli c7122, Escherichia coli str. K-12 substr. MDS42, Escherichia coli O103:H2 str. 12009, Escherichia coli SE11, Escherichia coli IAI1, Escherichia coli str. K-12 substr. W3110 Bacteria, Synthetic UP000000625 UP000069664, UP000036210, UP000035650, UP000033060, UP000033030, UP000017914, UP000031595, UP000030631, UP000029835, UP000029822, UP000029103, UP000027991, UP000027859, UP000027993, UP000027634, UP000027759, UP000027657, UP000027915, UP000027727, UP000027738, UP000027794, UP000027675, UP000027646, UP000027704, UP000027853, UP000027999, UP000028000, UP000027901, UP000028142, UP000027847, UP000028107, UP000027659, UP000027802, UP000027620, UP000028036, UP000027693, UP000028050, UP000028062, UP000028018, UP000028125, UP000028015, UP000027895, UP000027916, UP000027697, UP000027910, UP000027924, UP000027750, UP000027706, UP000027626, UP000027636, UP000027792, UP000027685, UP000027690, UP000027648, UP000027787, UP000027631, UP000027826, UP000027687, UP000028117, UP000027845, UP000028003, UP000028082, UP000028146, UP000028076, UP000028149, UP000027559, UP000027521, UP000027506, UP000027236, UP000027237, UP000024004, UP000023945, UP000024134, UP000023989, UP000024113, UP000023949, UP000023850, UP000024070, UP000023867, UP000024251, UP000023960, UP000024249, UP000024128, UP000024058, UP000024318, UP000024250, UP000024314, UP000024078, UP000023866, UP000024030, UP000024333, UP000020422, UP000023413, UP000020642, UP000020048, UP000019894, UP000018748, UP000014780, UP000018399, UP000018151, UP000018311, UP000017766, UP000017592, UP000017450, UP000017408, UP000017530, UP000017271, UP000017362, UP000017680, UP000016700, UP000016305, UP000016156, UP000016081, UP000016059, UP000015980, UP000016359, UP000016386, UP000016056, UP000016304, UP000016144, UP000016055, UP000016067, UP000016313, UP000016013, UP000016406, UP000016248, UP000016112, UP000016085, UP000016431, UP000016364, UP000015989, UP000016376, UP000016039, UP000017054, UP000016037, UP000016147, UP000016155, UP000014781, UP000014164, UP000014181, UP000014189, UP000014182, UP000014185, UP000014119, UP000014111, UP000014153, UP000014215, UP000014087, UP000014088, UP000014167, UP000014201, UP000012200, UP000012244, UP000012294, UP000012301, UP000012417, UP000012349, UP000012296, UP000012324, UP000012352, UP000012225, UP000012382, UP000012403, UP000012361, UP000012247, UP000012378, UP000012427, UP000012434, UP000012269, UP000012436, UP000012372, UP000012424, UP000012242, UP000012336, UP000012266, UP000012325, UP000012289, UP000014017, UP000012203, UP000012437, UP000012271, UP000012394, UP000012258, UP000012207, UP000012366, UP000012374, UP000012282, UP000012239, UP000012439, UP000012219, UP000012212, UP000012408, UP000012380, UP000012332, UP000012404, UP000012390, UP000012406, UP000012348, UP000012230, UP000012229, UP000012231, UP000012328, UP000012346, UP000012272, UP000012205, UP000012222, UP000012290, UP000012304, UP000012431, UP000012233, UP000012270, UP000012331, UP000012263, UP000012276, UP000012426, UP000012373, UP000012337, UP000012315, UP000012395, UP000012288, UP000012393, UP000012441, UP000012364, UP000012339, UP000012280, UP000012192, UP000012232, UP000012277, UP000012284, UP000012425, UP000012430, UP000012193, UP000012191, UP000012375, UP000012334, UP000012386, UP000012354, UP000012217, UP000012391, UP000012084, UP000012080, UP000011564, UP000011672, UP000011819, UP000010653, UP000010632, UP000010571, UP000010676, UP000010545, UP000010617, UP000010580, UP000010702, UP000010544, UP000010662, UP000010576, UP000010622, UP000010505, UP000010564, UP000010624, UP000007990, UP000007979, UP000007373, UP000007354, UP000006784, UP000006669, UP000009039, UP000004746, UP000004021, UP000004939, UP000004235, UP000003492, UP000004354, UP000005163, UP000003703, UP000003889, UP000003866, UP000005401, UP000003324, UP000003305, UP000005354, UP000004751, UP000004454, UP000006453, UP000003077, UP000003721, UP000004552, UP000003709, UP000032706, UP000010089, UP000003066, UP000005154, UP000003187, UP000003761, UP000003890, UP000003036, UP000005489, UP000005523, UP000003814, UP000003096, UP000003825, UP000003846, UP000004450, UP000003827, UP000005848, UP000004861, UP000003169, UP000004570, UP000003777, UP000003393, UP000005067, UP000004854, UP000005556, UP000003048, UP000004036, UP000006198, UP000002950, UP000003004, UP000003441, UP000004307, UP000005304, UP000004062, UP000005851, UP000003886, UP000006422, UP000003708, UP000004405, UP000004601, UP000005060, UP000003772, UP000010292, UP000003859, UP000008464, UP000004711, UP000004681, UP000002795, UP000003322, UP000005960, UP000003523, UP000005450, UP000004288, UP000006430, UP000004715, UP000005056, UP000004017, UP000003368, UP000003390, UP000005983, UP000003293, UP000005176, UP000003456, UP000005957, UP000004998, UP000001478, UP000016537, UP000005698, UP000003472, UP000001689, UP000001123, UP000027582, UP000024860, UP000019185, UP000017782, UP000011177, UP000009327, UP000005626, UP000000959, UP000008199, UP000007098 16131824, 447199670, 857138677, 838808710, 838794848, 838718969, 838715900, 834767093, 827620351, 827618326, 823075129, 823060485, 823044923, 823018145, 822982969, 822981722, 822972711, 822965093, 822962464, 822956258, 822917540, 822912901, 822893812, 822893341, 822071936, 821331548, 817593693, 817589554, 817585413, 817581273, 817577132, 817029392, 817025564, 817015598, 808732971, 808728610, 808720287, 808715866, 808711503, 808707144, 808702774, 808698393, 801070665, 788917238, 788906653, 788884435, 788881007, 765188175, 755815408, 755717561, 752308367, 752191820, 748272116, 748117996, 748114031, 748113126, 748105412, 748101299, 748072500, 748069155, 748059264, 748046784, 748028305, 748018372, 747266275, 742953323, 738568225, 732686429, 731472916, 730585188, 730030529, 730029774, 730022453, 729997102, 729982285, 729978493, 729967083, 729962438, 729942577, 729926652, 729921227, 729915632, 729906225, 729905086, 729882430, 729880311, 729874920, 729865563, 729857685, 729855994, 729848298, 729834423, 729833418, 729831250, 729818756, 729805889, 729796561, 729788900, 729787975, 729782779, 729775050, 724485319, 724474282, 699400699, 699398164, 699387870, 697408977, 695936557, 693350178, 685224249, 682121358, 678170641, 678162191, 678158429, 664686297, 660673043, 660656001, 660306619, 660295804, 660292768, 660270795, 660164628, 660132208, 660128093, 660109130, 660105627, 660051694, 660007572, 659995787, 659978137, 658703908, 652293217, 652267065, 652222669, 652211846, 652198395, 652175097, 652166262, 652161903, 652157249, 652154114, 652151763, 652137973, 652126579, 652108866, 652086008, 652082365, 652080840, 652038863, 651844716, 651821372, 651814787, 651795736, 651759052, 651737339, 651733576, 651724282, 651718207, 651677016, 651663569, 651657960, 651655261, 651349966, 650149673, 650133517, 650068379, 650060187, 650021566, 650009085, 649969605, 643346361, 636553736, 635911603, 635889434, 635876068, 632195115, 632189950, 611127614, 611010934, 608091041, 607787656, 607778414, 607735518, 607723039, 607713203, 607376148, 606997233, 606996430, 606966340, 606922085, 606881743, 606880479, 606867809, 606806333, 606801409, 606739400, 606735867, 606432439, 598731186, 598728554, 598715088, 598704543, 598687023, 597608853, 597601997, 564847987, 559784798, 558732275, 558727888, 558712198, 557934828, 556117638, 554986957, 554696542, 553690083, 553656410, 553604613, 553356048, 549815291, 544204355, 536013531, 535882188, 535802189, 535793552, 535776511, 535760588, 535748517, 535655699, 535628366, 535614092, 535610361, 535549049, 535500785, 535469150, 535360389, 535319529, 535274805, 535246216, 535134155, 535104130, 534983436, 534959296, 534949394, 534865382, 534842588, 534681757, 534602423, 514334454, 508486313, 508485781, 508470448, 508451838, 508447051, 508399947, 508374377, 508369405, 508361005, 508342483, 508313235, 508281962, 508267058, 477491322, 477487377, 477479565, 477473023, 477465923, 477453002, 477450646, 477448543, 477421027, 477413976, 477408714, 477392292, 477384534, 477380643, 477369102, 477294072, 477274040, 477271026, 477254791, 477243242, 477234320, 477231099, 477222708, 477218651, 477215815, 477207950, 477200779, 477197225, 477190421, 477185333, 477183934, 477176329, 477170502, 477160828, 477155841, 477141371, 477138924, 477126670, 477121734, 477099226, 477095221, 477084481, 477054631, 477050243, 477034968, 477034940, 477022604, 476893904, 476818272, 476803088, 476773172, 476758653, 476755040, 476743642, 476709854, 476687532, 476675974, 476668932, 476654082, 476368472, 476368441, 476360566, 476354124, 476346923, 476341704, 476331204, 476328655, 476316760, 476293380, 476286579, 476277413, 476274366, 476256535, 476246207, 476236805, 476227350, 476219202, 476193275, 476181017, 476176347, 476166970, 476164756, 476145657, 476144582, 476131744, 476119567, 476111041, 476031653, 472423501, 472409591, 449313676, 449313104, 443419984, 431652754, 431641393, 431605923, 431560949, 431476628, 431416530, 431358815, 431289143, 431248573, 431233876, 431226830, 431205184, 431175719, 431159433, 431088937, 408563803, 408562593, 408340231, 408224313, 408197190, 408189328, 397782836, 391308993, 391300805, 388405878, 388335655, 388334356, 386252425, 386237861, 386234176, 386225346, 386220194, 386181744, 386176921, 386165709, 386161766, 386152660, 386143956, 386119833, 385707982, 385153811, 384377096, 383476959, 383407635, 383390510, 378254888, 378250481, 378242173, 378239400, 378232512, 378226212, 378223475, 378213470, 378207941, 378197316, 378195096, 378194844, 378181796, 378181757, 378178617, 378164484, 378163987, 378160705, 378153920, 378145411, 378143641, 378137779, 378124045, 378122876, 378033842, 378023061, 378020724, 378009641, 378005597, 378003331, 377991133, 377988670, 377988001, 371591550, 345389532, 345384444, 345370788, 345368351, 345357368, 345332761, 342361167, 339417716, 332345984, 332105280, 331072272, 331036030, 324115426, 324017353, 323938889, 323380617, 323174494, 323161284, 320200166, 315617358, 315253067, 315063319, 310331387, 306905538, 301075999, 300842356, 300522874, 300453003, 300400715, 300318274, 299880884, 260451178, 238863632, 226838486, 194411990, 192925945, 169891290, 157069143, 1790427, 396333, 802137256, 687679063, 687674092, 678292748, 633887252, 571217856, 571177030, 557274160, 441609883, 412971964, 412965368, 359334108, 315138551, 259517484, 257761941, 238065980, 229558532, 226695849, 218363318, 209914732, 166987539, 85676075, 417994 AKO55144.1, KLX90971.1, KLX77271.1, KLX02308.1, KLW99266.1, AKM37565.1, AKK16085.1, AKK14309.1, KLH95609.1, KLH81323.1, KLH66213.1, KLH40618.1, KLH06438.1, KLH05214.1, KLG96490.1, KLG89065.1, KLG86555.1, KLG80653.1, KLG43067.1, KLG38942.1, KLG28828.1, KLG28704.1, KLD44092.1, AKH24651.1, AKF74272.1, AKF70134.1, AKF65994.1, AKF61855.1, AKF57716.1, KKO37536.1, KKO33881.1, KKO24286.1, AKD89806.1, AKD85446.1, AKD81083.1, AKD76663.1, AKD72301.1, AKD67943.1, AKD63574.1, AKD59194.1, AKA93162.1, KJW66745.1, KJW56698.1, KJW35836.1, KJW32529.1, KJD86294.1, KIQ44540.1, KIQ39400.1, AJG10986.1, KIN83593.1, AJE58550.1, KIH23428.1, KIH19662.1, KIH18914.1, KIH11943.1, KIH08104.1, KIG80215.1, KIG76988.1, KIG69150.1, KIG57420.1, KIG39936.1, KIG30535.1, KIG27588.1, AJB53992.1, KHQ71629.1, AIZ93234.1, AIZ53798.1, AIZ30474.1, KHJ18313.1, KHJ17591.1, KHJ10729.1, KHI86143.1, KHI71902.1, KHI68184.1, KHI57097.1, KHI52567.1, KHI33334.1, KHI18045.1, KHI12806.1, KHI07470.1, KHH98296.1, KHH97197.1, KHH75198.1, KHH73174.1, KHH67902.1, KHH58760.1, KHH51081.1, KHH49468.1, KHH42005.1, KHH28419.1, KHH27436.1, KHH25361.1, KHH13133.1, KHH00856.1, KHG91836.1, KHG84552.1, KHG83637.1, KHG78561.1, KHG71098.1, KHD44947.1, KHD34234.1, KGM79127.1, KGM76809.1, KGM67243.1, KGL70051.1, AIT32788.1, KGI46817.1, KGA86299.1, AIN34284.1, KFV38728.1, KFV30555.1, KFV26881.1, AIF39248.1, KEP12528.1, KEO95674.1, KEN95017.1, KEN85300.1, KEN82381.1, KEN61146.1, KEM57607.1, KEM26392.1, KEM22360.1, KEM03948.1, KEM00501.1, KEL47859.1, KEL06339.1, KEK94888.1, KEK77748.1, KEJ46194.1, KDZ96346.1, KDZ71936.1, KDZ30056.1, KDZ19799.1, KDZ07118.1, KDY85007.1, KDY76946.1, KDY72883.1, KDY68730.1, KDY65715.1, KDY63420.1, KDY50820.1, KDY40005.1, KDY23307.1, KDY01597.1, KDX98189.1, KDX96714.1, KDX56886.1, KDX18520.1, KDW96283.1, KDW90118.1, KDW71717.1, KDW36911.1, KDW16061.1, KDW12431.1, KDW03609.1, KDV97699.1, KDV59230.1, KDV45840.1, KDV40287.1, KDV37591.1, KDV17650.1, KDU69041.1, KDU53252.1, KDT90481.1, KDT82470.1, KDT45347.1, KDT33435.1, KDS95464.1, KDP18460.1, KDM85018.1, KDG92024.1, KDG70036.1, KDG56836.1, KDA87638.1, KDA83101.1, EZK27007.1, EZJ15836.1, EZG30252.1, EZE67899.1, EZE58881.1, EZE17563.1, EZE05568.1, EZD96012.1, EZA68764.1, EZA26172.1, EZA25391.1, EYZ96984.1, EYZ55067.1, EYZ16757.1, EYZ15548.1, EYZ03409.1, EYY45448.1, EYY40750.1, EYX82183.1, EYX78836.1, EYU90915.1, EYE34389.1, EYE31971.1, EYE19455.1, EYE09948.1, EYD94039.1, EYB54896.1, EYB48187.1, ETD58906.1, ESV01990.1, EST81938.1, EST78260.1, EST63498.1, ESS98258.1, ESP06267.1, ESL31557.1, ESK02090.1, ESE06278.1, ESD74530.1, ESD25145.1, ESA83032.1, AGX35909.1, AGW11047.1, ERB12763.1, ERA13598.1, EQZ34997.1, EQZ26568.1, EQZ09812.1, EQY94209.1, EQY82473.1, EQX91724.1, EQX64945.1, EQX50915.1, EQX47277.1, EQW87108.1, EQW40080.1, EQW09233.1, EQV02674.1, EQU62325.1, EQU17998.1, EQT89827.1, EQS79451.1, EQS50163.1, EQR31742.1, EQR07973.1, EQQ98263.1, EQQ15900.1, EQP93542.1, EQO37686.1, EQN60248.1, EPH47106.1, EOW55536.1, EOW55012.1, EOW39958.1, EOW21638.1, EOW16951.1, EOV70663.1, EOV45617.1, EOV40724.1, EOV32396.1, EOV14169.1, EOU85426.1, EOU54987.1, EOU40299.1, ENH52568.1, ENH48858.1, ENH41651.1, ENH35332.1, ENH28437.1, ENH16201.1, ENH13969.1, ENH12102.1, ENG86113.1, ENG79750.1, ENG74871.1, ENG59409.1, ENG52032.1, ENG48356.1, ENG37417.1, ENF65139.1, ENF46127.1, ENF43236.1, ENF27768.1, ENF16830.1, ENF08435.1, ENF05454.1, ENE97579.1, ENE93740.1, ENE90997.1, ENE83669.1, ENE76721.1, ENE73250.1, ENE66585.1, ENE61635.1, ENE60290.1, ENE53068.1, ENE47422.1, ENE38092.1, ENE33448.1, ENE19682.1, ENE17497.1, ENE05934.1, ENE01243.1, END79778.1, END75909.1, END65572.1, END37419.1, END33320.1, END19327.1, END19301.1, END07550.1, ENB84896.1, ENB18355.1, ENB04251.1, ENA75591.1, ENA62282.1, ENA58928.1, ENA47952.1, ENA14889.1, EMZ92888.1, EMZ81615.1, EMZ74723.1, EMZ60275.1, EMX85615.1, EMX85585.1, EMX77818.1, EMX71426.1, EMX64277.1, EMX59108.1, EMX48679.1, EMX46155.1, EMX34405.1, EMX11390.1, EMX04662.1, EMW95577.1, EMW92576.1, EMW75257.1, EMW65302.1, EMW56183.1, EMW46898.1, EMW39138.1, EMW13831.1, EMW01962.1, EMV97370.1, EMV88200.1, EMV86031.1, EMV67515.1, EMV66468.1, EMV53926.1, EMV42256.1, EMV33910.1, EMU57325.1, EMS05966.1, EMR92447.1, EMD03875.1, EMD03330.1, AGC84888.1, ELJ19884.1, ELJ09134.1, ELI75308.1, ELI34453.1, ELH56417.1, ELG99008.1, ELG45461.1, ELF79885.1, ELF42766.1, ELF29458.1, ELF23985.1, ELF03688.1, ELE75718.1, ELE59986.1, ELD94765.1, EKK39931.1, EKK38752.1, EKJ54737.1, EKI48030.1, EKI22456.1, EKI15067.1, EJK93702.1, EIQ66678.1, EIQ58709.1, EIL66294.1, EIL02212.1, EIL00952.1, EIJ02117.1, EII74802.1, EII66156.1, EII47676.1, EII36658.1, EIH64505.1, EIH54400.1, EIH32229.1, EIH23569.1, EIH03949.1, EIG90424.1, EIG68475.1, EIG45002.1, EIF15837.1, EIE34993.1, EID68887.1, AFH13878.1, AFH15468.1, EHY14749.1, EHY10386.1, EHY02136.1, EHX99390.1, EHX92611.1, EHX86401.1, EHX83697.1, EHX73783.1, EHX68327.1, EHX57798.1, EHX55601.1, EHX55353.1, EHX42458.1, EHX42421.1, EHX39380.1, EHX25428.1, EHX24937.1, EHX21696.1, EHX14998.1, EHX06576.1, EHX04831.1, EHW99047.1, EHW85459.1, EHW84302.1, EHV96413.1, EHV85740.1, EHV83463.1, EHV72596.1, EHV68598.1, EHV66375.1, EHV54285.1, EHV51847.1, EHV51183.1, EHN80506.1, EGX19337.1, EGX14308.1, EGX02763.1, EGX00349.1, EGW89566.1, EGW65216.1, EGU25313.1, AEJ59388.1, AEE59318.1, EGJ08626.1, EGI43606.1, EGI08267.1, EGC09371.1, EGB86572.1, EGB35109.1, ADX52885.1, EFZ60119.1, EFZ47194.1, EFW74755.1, EFU97964.1, EFU33035.1, ADT77646.1, EFP98652.1, EFN36071.1, EFK90805.1, EFK70116.1, EFK43943.1, EFK16623.1, EFJ84253.1, EFJ68058.1, EFI89095.1, ACX41600.1, ACR65630.1, EEH70516.1, EDX28303.1, EDV80592.1, ACB04997.1, ABV08398.1, AAC76968.1, AAC43092.1 NP_418422.1, WP_001276926.1 B7M7Q3, C5A0T5, B1XBZ7, A8A794, P30136, B6I5K5 THIC_ECO8A, THIC_ECOBW, THIC_ECODH, THIC_ECOHS, THIC_ECOLI, THIC_ECOSE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5581472, 3476182, 2463176, 18026, 7705075, 5499092, 5867766, 7677593, 2472283, 1242332 fig|1116163.3.peg.4442, fig|1227813.3.peg.3801, fig|1116099.3.peg.4576, fig|83333.1.peg.3907, fig|1116160.3.peg.4367, fig|1116001.3.peg.4940, fig|868191.3.peg.4664, fig|670892.3.peg.2262, fig|1116170.3.peg.4195, fig|868195.3.peg.4603, fig|913090.3.peg.4681, fig|913087.3.peg.1499, fig|1116029.3.peg.4630, fig|1116078.3.peg.4314, fig|1090926.6.peg.628, fig|868207.3.peg.4653, fig|1116133.3.peg.4573, fig|1116089.3.peg.4047, fig|1116184.3.peg.4275, fig|868208.3.peg.4541, fig|1116180.3.peg.4621, fig|869670.3.peg.87, fig|679206.4.peg.4376, fig|1116104.3.peg.4467, fig|1116162.3.peg.4404, fig|556266.3.peg.4543, fig|752788.3.peg.2338, fig|1116155.3.peg.4690, fig|1116034.3.peg.4584, fig|1116169.3.peg.4080, fig|1181768.3.peg.1469, fig|1182729.3.peg.4469, fig|1169359.3.peg.302, fig|316385.5.peg.4125, fig|1182703.3.peg.4797, fig|754084.3.peg.4239, fig|670888.3.peg.4760, fig|1182716.3.peg.21, fig|1116028.3.peg.4603, fig|868188.3.peg.4808, fig|868200.3.peg.4438, fig|1116178.3.peg.4644, fig|868210.3.peg.4828, fig|749538.3.peg.952, fig|868198.3.peg.4811, fig|1116031.3.peg.4540, fig|679202.3.peg.4706, fig|340185.3.peg.4780, fig|1169663.3.peg.876, fig|1116019.3.peg.4611, fig|766166.3.peg.4911, fig|1050617.5.peg.4836, fig|585034.4.peg.4094, fig|1182684.3.peg.4584, fig|1116092.3.peg.4618, fig|1182668.3.peg.4505, fig|1110693.3.peg.3420, fig|1068608.3.peg.3778, fig|1182700.3.peg.2943, fig|1116097.3.peg.4099, fig|868206.3.peg.4823, fig|1116094.3.peg.4074, fig|457401.3.peg.4737, fig|550687.3.peg.4701, fig|1116014.3.peg.4311, fig|1125649.3.peg.4699, fig|656372.3.peg.4744, fig|868196.3.peg.4336, fig|1116153.3.peg.4946, fig|1078033.4.peg.1566, fig|879462.4.peg.4026, fig|868168.3.peg.4770, fig|868187.3.peg.4632, fig|1116045.3.peg.4384, fig|1116157.3.peg.4706, fig|595495.4.peg.4766, fig|1169352.3.peg.4934, fig|869687.4.peg.3660, fig|1116079.3.peg.4540, fig|1116102.3.peg.4371, fig|1116168.3.peg.4260, fig|1181743.3.peg.224, fig|1169379.3.peg.4479, fig|331112.3.peg.3943, fig|868162.3.peg.4786, fig|595496.3.peg.3992, fig|1167694.3.peg.4585, fig|869688.4.peg.2378, fig|1116026.3.peg.4370, fig|679205.4.peg.723, fig|1116093.3.peg.4650, fig|1116017.3.peg.4327, fig|1116129.3.peg.4961, fig|1116134.3.peg.4597, fig|1169396.3.peg.4415, fig|754088.3.peg.4807, fig|1181767.3.peg.4641, fig|1182702.3.peg.224, fig|316385.7.peg.4211, fig|1137135.3.peg.728, fig|749533.3.peg.5010, fig|1169388.3.peg.4088, fig|868190.3.peg.4488, fig|754090.3.peg.4767, fig|1116121.3.peg.4518, fig|868160.3.peg.4657, fig|511145.12.peg.4108, fig|1116077.3.peg.4640, fig|868203.3.peg.4711, fig|1182728.3.peg.2093, fig|1116120.3.peg.4679, fig|1116172.3.peg.4673, fig|1116161.3.peg.4549, fig|869691.3.peg.4927, fig|1116187.3.peg.4666, fig|1116076.3.peg.4383, fig|1116021.3.peg.4410, fig|1116095.3.peg.4648, fig|1182715.3.peg.5076, fig|869679.3.peg.1310, fig|696406.3.peg.4724, fig|1182678.3.peg.5019, fig|1005442.3.peg.4330, fig|1116005.3.peg.4023, fig|1005564.3.peg.4537, fig|566546.3.peg.4747, fig|869680.3.peg.2701, fig|1078030.10.peg.1896, fig|1101440.4.peg.4377, fig|1005567.3.peg.4149, fig|1182706.3.peg.232, fig|1116114.3.peg.4117, fig|868169.3.peg.4442, fig|670894.3.peg.2444, fig|1125650.3.peg.3787, fig|1246623.3.peg.46, fig|670903.3.peg.4603, fig|754081.3.peg.4441, fig|1116140.3.peg.4677, fig|1116000.3.peg.4451, fig|656408.3.peg.4481, fig|1116107.3.peg.3780, fig|868184.3.peg.4629, fig|585395.4.peg.4970, fig|868165.3.peg.4788, fig|475609.3.peg.4191, fig|868163.3.peg.4680, fig|344601.3.peg.4299, fig|868193.3.peg.5251, fig|1116188.3.peg.4329, fig|1125646.3.peg.4679, fig|1116090.3.peg.4636, fig|1227814.3.peg.4001, fig|1125648.3.peg.3830, fig|1144303.3.peg.4303, fig|1090930.3.peg.4119, fig|1116156.3.peg.4617, fig|1116105.3.peg.4586, fig|1116167.3.peg.4573, fig|1116003.3.peg.4464, fig|1116166.3.peg.4281, fig|1090929.3.peg.3451, fig|1115999.3.peg.4478, fig|670890.3.peg.922, fig|1169863.3.peg.4793, fig|1115997.3.peg.5163, fig|749540.3.peg.2258, fig|1116165.3.peg.4624, fig|868192.3.peg.5187, fig|1115998.3.peg.293, fig|868202.3.peg.4783, fig|1116176.3.peg.4618, fig|1116173.3.peg.4261, fig|1116109.3.peg.4525, fig|868186.3.peg.4612, fig|656405.3.peg.4957, fig|1116073.3.peg.4480, fig|1169333.3.peg.4605, fig|670896.3.peg.4599, fig|868204.3.peg.4634, fig|1116018.3.peg.4408, fig|1165941.3.peg.4282, fig|1116074.3.peg.4277, fig|1005562.3.peg.4428, fig|1116037.3.peg.3577, fig|868161.3.peg.4927, fig|1116122.3.peg.4873, fig|1182658.3.peg.5135, fig|754087.3.peg.4669, fig|868167.3.peg.4577, fig|749548.3.peg.1711, fig|869677.3.peg.3418, fig|1116177.3.peg.4994, fig|1116174.3.peg.4257, fig|656414.3.peg.4533, fig|754078.3.peg.4369, fig|749539.3.peg.3530, fig|1005464.3.peg.4172, fig|536056.3.peg.4252, fig|1116027.3.peg.4549, fig|1005462.3.peg.4201, fig|1116020.3.peg.4631, fig|1116004.3.peg.4391, fig|316407.3.peg.3160, fig|1169397.3.peg.4264, fig|1116101.3.peg.4005, fig|243090.1.peg.745, fig|1125651.3.peg.4838, fig|1116191.3.peg.4272, fig|457400.3.peg.2094, fig|868194.3.peg.4903, fig|868199.3.peg.4414, fig|868197.3.peg.4093, fig|1274814.3.peg.147, fig|1125636.3.peg.4531, fig|868164.3.peg.4557, fig|562.1188.peg.4252, fig|869694.3.peg.328, fig|869671.3.peg.3514, fig|1182730.3.peg.287, fig|868189.3.peg.4868, fig|1116106.3.peg.3918, fig|1116164.3.peg.4598, fig|1182738.3.peg.21, fig|749544.3.peg.686, fig|869675.3.peg.5103, fig|1182688.3.peg.222, fig|656413.3.peg.3092, fig|1169320.3.peg.4950, fig|1116175.3.peg.4600, fig|1116035.3.peg.4572, fig|869690.3.peg.1242, fig|1165940.3.peg.4453, fig|945434.3.peg.3036, fig|409438.11.peg.4461, fig|1116011.3.peg.4336, fig|1181744.3.peg.5140, fig|868209.3.peg.4478, fig|1116012.3.peg.4723, fig|1182733.3.peg.1578, fig|1116181.3.peg.4718 626 631 yes 437599 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 349521 Hahella chejuensis KCTC 2396 Bacteria UP000000238 83631089, 109895168 ABC27056.1 Q2SQL8 THIC_HAHCH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1092228 fig|349521.5.peg.129 634 638 yes 437600 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 84159, 342108 Magnetospirillum magneticum, Magnetospirillum magneticum AMB-1 Bacteria UP000007058 760060219, 109895169 WP_043743084.1 Q2WAV0 THIC_MAGSA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1101142 fig|342108.5.peg.221 602 613 yes 437601 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2203, 323259 Methanospirillum hungatei, Methanospirillum hungatei JF-1 Archaea UP000001941 499767966, 88188438, 109895170 ABD41435.1 WP_011448700.1 Q2FQY7 THIC_METHJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1258393 fig|323259.5.peg.1810 426 426 yes 437602 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2257, 348780 Natronomonas pharaonis, Natronomonas pharaonis DSM 2160 Archaea UP000002698 499642089, 76801748, 109895171, 76557613 WP_011322823.1, YP_326756.1 Q3IRP7 THIC_NATPD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1115515 fig|348780.3.peg.888 454 477 yes 437603 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1231, 323848 Nitrosospira multiformis, Nitrosospira multiformis ATCC 25196 Bacteria UP000002718 499700849, 82411468, 109895172 ABB75577.1 WP_011381583.1 Q2Y6P4 THIC_NITMU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1126010 fig|323848.3.peg.2485 626 635 yes 437604 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1229, 314279, 473788, 323261 Nitrosococcus oceani, Nitrosococcus oceani C-27, Nitrosococcus oceani AFC27, Nitrosococcus oceani ATCC 19707 Bacteria UP000028833, UP000028839, UP000002787, UP000006838 488901217, 672880462, 672876340, 207088294, 76884594, 109895173 KFI21481.1, KFI18303.1, EDZ65566.1, ABA59275.1 WP_002812306.1 Q3J7C1 THIC_NITOC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1123419 fig|473788.3.peg.2541, fig|323261.3.peg.1338 621 624 yes 437605 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 913, 323098 Nitrobacter winogradskyi, Nitrobacter winogradskyi Nb-255 Bacteria UP000002531 499634942, 74421522, 109895174 ABA05721.1 WP_011315676.1 Q3SPS0 THIC_NITWN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1119818 fig|323098.3.peg.2367 636 646 yes 437606 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 48935, 279238 Novosphingobium aromaticivorans, Novosphingobium aromaticivorans DSM 12444 Bacteria UP000009134 499764740, 87135522, 109895175 ABD26264.1 WP_011445474.1 Q2G7A9 THIC_NOVAD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1262778 fig|279238.18.peg.1863 619 626 yes 437607 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1100, 319225 Pelodictyon luteolum, Chlorobium luteolum DSM 273 Bacteria UP000002709 499677460, 78167224, 109895176 ABB24322.1 WP_011358194.1 Q3B2V9 THIC_CHLL7 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1128034 fig|319225.3.peg.1447 564 565 yes 437608 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1219, 59920 Prochlorococcus marinus, Prochlorococcus marinus str. NATL2A Bacteria UP000002535 499614798, 72002876, 109895177 AAZ58678.1 WP_011295532.1 Q46IK0 THIC_PROMT Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1202473 fig|59920.3.peg.777 464 466 yes 437609 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 29438, 264730 Pseudomonas savastanoi, Pseudomonas syringae pv. phaseolicola 1448A Bacteria UP000037867, UP000000551 499480903, 71556183, 109895178 AAZ35394.1 WP_011167543.1 Q48P32 THIC_PSE14 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 877402 fig|264730.3.peg.587 627 629 yes 437610 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 136843, 220664 Pseudomonas fluorescens Pf-5 Bacteria UP000008540 499371333, 68348341, 109895179 AAY95947.1 WP_011058911.1 Q4KJA1 THIC_PSEF5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 871175 fig|220664.3.peg.2022 628 629 yes 437611 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1649845, 214092, 632, 1234661, 385969, 649716, 748672, 748678, 360102, 1035377, 633, 502801, 386656, 273123, 385964, 1455696, 755896, 1330535, 1330536, 1330537, 1159617, 992156, 992140, 547048, 637386, 687916, 637385, 637382, 545431, 547046, 547047, 377628, 404216, 404218, 404217, 404215, 360099, 404214, 373665, 349747, 412420, 229193, 187410, 1341643, 1218101 Yersinia pestis CO92, Yersinia pestis, Yersinia pestis subsp. pestis bv. Orientalis, Yersinia pestis subsp. ulegeica, Yersinia pestis Pestoides G, Yersinia pseudotuberculosis str. PA3606, Yersinia pestis str. Pestoides B, Yersinia pestis Antiqua, Yersinia pestis A1122, Yersinia pseudotuberculosis, Yersinia pseudotuberculosis PB1/+, Yersinia pestis Pestoides F, Yersinia pseudotuberculosis IP 32953, Yersinia pestis subsp. pestis, Yersinia pestis EV NIIEG, Yersinia pestis 9, Yersinia pestis 113, Yersinia pestis S3, Yersinia pestis 24H, Yersinia pestis INS, Yersinia pestis PY-54, Yersinia pestis PY-14, Yersinia pestis biovar Medievalis str. Harbin 35, Yersinia pestis Z176003, Yersinia pestis KIM D27, Yersinia pestis D182038, Yersinia pestis D106004, Yersinia pestis Pestoides A, Yersinia pestis biovar Orientalis str. PEXU2, Yersinia pestis biovar Orientalis str. India 195, Yersinia pestis Nepal516, Yersinia pestis biovar Mediaevalis str. K1973002, Yersinia pestis biovar Antiqua str. UG05-0454, Yersinia pestis biovar Orientalis str. MG05-1020, Yersinia pestis biovar Antiqua str. B42003004, Yersinia pestis biovar Antiqua str. E1979001, Yersinia pestis biovar Orientalis str. F1991016, Yersinia pestis biovar Orientalis str. IP275, Yersinia pseudotuberculosis IP 31758, Yersinia pestis CA88-4125, Yersinia pestis biovar Microtus str. 91001, Yersinia pestis KIM 10, Yersinia sp. 12-219N1, Yersinia pseudotuberculosis NBRC 105692 Bacteria UP000000815 UP000057789, UP000031825, UP000034830, UP000037981, UP000031851, UP000031865, UP000031868, UP000031888, UP000002491, UP000047176, UP000031905, UP000031859, UP000031850, UP000028646, UP000053153, UP000018873, UP000017109, UP000018875, UP000018864, UP000009339, UP000004341, UP000003873, UP000008088, UP000000932, UP000006249, UP000002567, UP000000285, UP000003607, UP000004091, UP000004452, UP000000282, UP000005612, UP000005075, UP000005614, UP000006441, UP000003095, UP000005815, UP000004430, UP000002412, UP000003742, UP000047420, UP000018737 488139474, 218930744, 816661973, 816659167, 805411798, 767760391, 755458669, 755452528, 755446805, 755444212, 755439209, 755431740, 755422748, 755419652, 755406928, 755398905, 755387951, 755386162, 755372176, 755370527, 755364777, 755361402, 755355296, 755341415, 755294558, 685177741, 685064434, 682102687, 668663016, 594136162, 550634384, 550629872, 550628720, 550628470, 411173687, 391569943, 391486904, 342853535, 320013661, 294355867, 270337427, 262367402, 262363474, 229704174, 229695787, 229686968, 229682388, 186696673, 167054184, 167048186, 166957151, 166204407, 165989044, 165919653, 165913860, 152960857, 149289335, 145212679, 108781515, 108774041, 45437722, 21957189, 813882102, 813842061, 812257516, 806890622, 802892498, 802353490, 566683615, 115349355, 81640661, 51587927, 24638275 KKM54083.1, KKM51385.1, AKB86554.1, KJG85105.1, AJK23381.1, AJK15702.1, AJK10789.1, AJJ44328.1, AJJ39329.1, AJJ88311.1, AJJ79326.1, AJJ32660.1, AJJ76045.1, AJJ16111.1, AJJ69521.1, AJJ67733.1, AJJ05548.1, AJJ03901.1, AJI98151.1, AJJ55286.1, AJJ49186.1, AJK06927.1, AJI91742.1, KGA65366.1, KGA55514.1, AIN14564.1, KFB59456.1, EXU71055.1, ERP84634.1, ERP80671.1, ERP79568.1, ERP79328.1, EKS43729.1, EIS17472.1, EIR42893.1, AEL72088.1, ADV97232.1, ADE66208.1, EFA48204.1, ACY63959.1, ACY60195.1, EEO91185.1, EEO85834.1, EEO79044.1, EEO78478.1, ACC87302.1, EDR64009.1, EDR59594.1, EDR55172.1, EDR48887.1, EDR41345.1, EDR36986.1, EDR32478.1, ABS48318.1, EDM39414.1, ABP42086.1, ABG15573.1, ABG16560.1, AAS63272.1, AAM84080.1 WP_002210682.1, YP_002348619.1 Q8ZAQ2, Q66FP5 THIC_YERPE, THIC_YERPS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 10389835, 271051, 4590029, 147024, 4284627, 3520715, 2028057, 5724507, 1981469, 4303262, 4298593, 4293794, 618916, 5720234, 681072, 6965426, 4429075, 4289525, 3579064 fig|187410.1.peg.481, fig|547046.3.peg.1694, fig|545431.3.peg.1417, fig|547047.3.peg.4454, fig|1084227.3.peg.387, fig|687916.3.peg.2588, fig|637382.3.peg.4369, fig|404214.5.peg.4751, fig|377628.10.peg.390, fig|273123.10.peg.458, fig|502801.6.peg.323, fig|1286087.3.peg.2820, fig|349747.3.peg.2862, fig|229193.1.peg.2991, fig|1084234.3.peg.2468, fig|1286084.3.peg.823, fig|1084229.3.peg.2798, fig|1084231.3.peg.77, fig|1286089.3.peg.2859, fig|1159617.4.peg.4040, fig|1035377.4.peg.1431, fig|1286088.3.peg.2392, fig|1324608.3.peg.1754, fig|649715.3.peg.1875, fig|404215.6.peg.4616, fig|1194970.3.peg.4020, fig|1084226.3.peg.3045, fig|637385.3.peg.4376, fig|404216.5.peg.4349, fig|547048.4.peg.503, fig|1084228.3.peg.1411, fig|992140.3.peg.3961, fig|373665.6.peg.3011, fig|404217.5.peg.4967, fig|1084233.3.peg.2893, fig|1286086.3.peg.3659, fig|1084232.3.peg.803, fig|360099.5.peg.4701, fig|992156.3.peg.3643, fig|360102.10.peg.4385, fig|412420.6.peg.4385, fig|386656.4.peg.3664, fig|214092.1.peg.3705, fig|1291550.3.peg.678, fig|404218.5.peg.4820, fig|1325475.3.peg.2420, fig|1324587.3.peg.1248, fig|637386.3.peg.4538, fig|1084230.3.peg.3203 651 681 yes 437612 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 312306, 384676 Pseudomonas entomophila, Pseudomonas entomophila L48 Bacteria UP000000658 499855243, 122401604, 95112889 WP_011535977.1 Q1I419 THIC_PSEE4 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2050863 fig|384676.6.peg.4295 625 626 yes 437613 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 288, 342610 Pseudoalteromonas atlantica, Pseudoalteromonas atlantica T6c Bacteria UP000001981 499894011, 109700529 ABG40449.1 WP_011574745.1 fig|342610.3.peg.3592 620 628 yes 437614 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1854, 981426, 106370 Frankia sp. Thr, Frankia sp. CcI3 Bacteria UP000022636, UP000001937 499754114, 602263785, 86565961, 109895167 EYT93012.1, ABD09770.1 WP_011434848.1 Q2JG22 THIC_FRACC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1245903 fig|106370.11.peg.375 617 652 yes 437615 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 95486, 331272, 331271 Burkholderia cenocepacia, Burkholderia cenocepacia HI2424, Burkholderia cenocepacia AU 1054 Bacteria UP000065887, UP000000776, UP000002400 499864287, 721515944, 116647334, 105892487, 166228017, 123072264 KGY59381.1, ABK07975.1, ABF75652.1 WP_011545021.1 Q1BXK3, A0K648 THIC_BURCA, THIC_BURCH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1884412, 1891374 fig|331272.3.peg.4529, fig|331271.3.peg.3048 642 643 yes 437616 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 34, 246197 Myxococcus xanthus, Myxococcus xanthus DK 1622 Bacteria UP000002402 499873504, 108461475, 123247627 ABF86660.1 WP_011554238.1 Q1D4L3 THIC_MYXXD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1755643 fig|246197.24.peg.4178, fig|246197.19.peg.3788 621 624 yes 437617 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28232, 691164, 269799 Geobacter metallireducens, Geobacter metallireducens RCH3, Geobacter metallireducens GS-15 Bacteria UP000003286, UP000007073 490648845, 373559215, 78192947, 109895139 EHP85521.1, ABB30714.1 WP_004513840.1 Q39YG0 THIC1_GEOMG Phosphomethylpyrimidine synthase 1 {ECO:0000255|HAMAP-Rule:MF_00089} 1088947 fig|691164.3.peg.2496, fig|269799.3.peg.499 432 435 yes 437618 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2208, 1434109, 269797 Methanosarcina barkeri, Methanosarcina barkeri str. Wiesmoor, Methanosarcina barkeri str. Fusaro Archaea UP000033038, UP000008156 499624894, 805399139, 72395304, 109895140 AKB49659.1, AAZ69577.1 WP_011305628.1 Q46EW5, A0A0E3QIH1 THIC1_METBF Phosphomethylpyrimidine synthase 1 {ECO:0000255|HAMAP-Rule:MF_00089} A0A0E3QIH1_METBA 1106114 fig|269797.3.peg.780 428 428 yes 437619 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2317, 339860 Methanosphaera stadtmanae, Methanosphaera stadtmanae DSM 3091 Archaea UP000001931 499725110, 84372375, 109895141 ABC56645.1 WP_011405844.1 Q2NHI8 THIC1_METST Phosphomethylpyrimidine synthase 1 {ECO:0000255|HAMAP-Rule:MF_00089} 1109544 fig|339860.6.peg.225 429 429 yes 437620 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1525, 264732 Moorella thermoacetica, Moorella thermoacetica ATCC 39073 Bacteria UP000067720, UP000007053 499712180, 83590248, 83573162, 109895142 ABC19714.1 WP_011392914.1, YP_430257.1 Q2RIM5 THIC1_MOOTA Phosphomethylpyrimidine synthase 1 {ECO:0000255|HAMAP-Rule:MF_00089} 1112364 fig|264732.11.peg.1506 431 432 yes 437621 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 19, 338963 Pelobacter carbinolicus, Pelobacter carbinolicus DSM 2380 Bacteria UP000002534 499659281, 77544035, 109895143 ABA87597.1 WP_011340015.1 Q3A7P7 THIC1_PELCD Phosphomethylpyrimidine synthase 1 {ECO:0000255|HAMAP-Rule:MF_00089} 1909077 fig|338963.3.peg.1480 593 596 yes 437622 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28232, 691164, 269799 Geobacter metallireducens, Geobacter metallireducens RCH3, Geobacter metallireducens GS-15 Bacteria UP000003286, UP000007073 490647851, 373560878, 78195361, 109895144 EHP87127.1, ABB33128.1 WP_004512846.1 Q39RJ6 THIC2_GEOMG Phosphomethylpyrimidine synthase 2 {ECO:0000255|HAMAP-Rule:MF_00089} 1091428 fig|691164.3.peg.1503, fig|269799.3.peg.3142 436 436 yes 437623 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2208, 1434109, 269797 Methanosarcina barkeri, Methanosarcina barkeri str. Wiesmoor, Methanosarcina barkeri str. Fusaro Archaea UP000033038, UP000008156 499626372, 805401346, 72396787, 109895145 AKB51866.1, AAZ71060.1 WP_011307106.1 Q46AN2, A0A0E3LLU2 THIC2_METBF Phosphomethylpyrimidine synthase 2 {ECO:0000255|HAMAP-Rule:MF_00089} A0A0E3LLU2_METBA 1107683 fig|269797.3.peg.1607 428 428 yes 437624 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2317, 339860 Methanosphaera stadtmanae, Methanosphaera stadtmanae DSM 3091 Archaea UP000001931 499725132, 84372397, 109895146 ABC56667.1 WP_011405866.1 Q2NHG6 THIC2_METST Phosphomethylpyrimidine synthase 2 {ECO:0000255|HAMAP-Rule:MF_00089} 1109567 fig|339860.6.peg.247 421 434 yes 437625 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 117207, 317655 Sphingopyxis alaskensis, Sphingopyxis alaskensis RB2256 Bacteria UP000006578 499861920, 98977928, 123078163 ABF54079.1 WP_011542654.1 Q1GQJ3 THIC_SPHAL Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1837152 fig|317655.9.peg.2292, fig|317655.17.peg.2460 622 630 yes 437626 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 19, 338963 Pelobacter carbinolicus, Pelobacter carbinolicus DSM 2380 Bacteria UP000002534 499661256, 77545913, 109895148 ABA89475.1 WP_011341990.1 Q3A2D2 THIC2_PELCD Phosphomethylpyrimidine synthase 2 {ECO:0000255|HAMAP-Rule:MF_00089} 1911116 fig|338963.3.peg.543 430 430 yes 437627 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1525, 264732 Moorella thermoacetica, Moorella thermoacetica ATCC 39073 Bacteria UP000067720, UP000007053 499712491, 83590559, 83573473, 109895149 ABC20025.1 WP_011393225.1, YP_430568.1 Q2RHR4 THIC3_MOOTA Phosphomethylpyrimidine synthase 3 {ECO:0000255|HAMAP-Rule:MF_00089} 1112688 fig|264732.11.peg.1866 432 432 yes 437628 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 161493, 290397 Anaeromyxobacter dehalogenans, Anaeromyxobacter dehalogenans 2CP-C Bacteria UP000001935 499739965, 85774579, 109895150 ABC81416.1 WP_011420699.1 Q2IID8 THIC_ANADE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1298402 fig|290397.13.peg.1638 456 463 yes 437629 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 770, 234826 Anaplasma marginale, Anaplasma marginale str. St. Maries Bacteria UP000006557 497953259, 109895151 WP_010267415.1 Q5PB42 THIC_ANAMM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 820736, 5499761, 10348413 fig|1000937.3.peg.646, fig|517437.3.peg.380, fig|234826.10.peg.1015, fig|320483.3.peg.382, fig|234826.3.peg.444 552 553 yes 437630 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 948, 1173064, 1184253, 212042 Anaplasma phagocytophilum, Anaplasma phagocytophilum JM, Anaplasma phagocytophilum HZ2, Anaplasma phagocytophilum HZ Bacteria UP000033356, UP000015043, UP000015041, UP000001943 499769977, 526277708, 526276460, 88598979, 109895152 AGR80105.1, AGR78858.1, ABD44449.1 WP_011450711.1 Q2GKB1 THIC_ANAPZ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1301739 fig|212042.5.peg.589 557 557 yes 437631 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1172, 240292 Anabaena variabilis, Anabaena variabilis ATCC 29413 Bacteria UP000002533 499636507, 75700307, 109895153 ABA19983.1 WP_011317241.1 Q3MGA3 THIC_ANAVT Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1047981 fig|240292.3.peg.958 455 457 yes 437632 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 521, 360910 Bordetella avium, Bordetella avium 197N Bacteria UP000001977 501384388, 115421351, 109895154 WP_012415954.1 Q2L083 THIC_BORA1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5517341 fig|360910.3.peg.263 636 637 yes 437633 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 32008, 272560, 28450, 1249469, 1249470, 331978, 1249658, 441156, 1249472, 1249473, 360118, 884204, 1435985, 1439858, 1439859, 1435993, 1435366, 1435368, 1434207, 1437005, 1435983, 1435998, 1435986, 1435996, 1435992, 1435991, 1435982, 1435999, 1436999, 1435995, 1435997, 1435370, 1434195, 1434203, 1434192, 1434927, 1434199, 1435369, 1434209, 1434211, 1435367, 1434205, 1434194, 1434198, 1435990, 1435048, 1434926, 1435374, 1435363, 1435050, 1434932, 1434928, 1435362, 1434925, 1435364, 1435373, 1434931, 1439853, 1435372, 1249477, 1487955, 1487954, 1306419, 1306418, 1306417, 1306420, 1306421, 557724, 1408264, 1249659, 1249471, 1249474, 1249468, 1249476, 1241583, 1343079, 1335307, 1247713, 1229785, 1086034, 1086036, 1086033, 1086032, 1085027, 320371, 357347, 536230, 595498, 331109, 320374, 425067, 357348, 320373, 320372 Burkholderia pseudomallei K96243, Burkholderia pseudomallei, Burkholderia pseudomallei MSHR1328, Burkholderia pseudomallei MSHR11079, Burkholderia pseudomallei Pasteur 52237, Burkholderia pseudomallei PB08298010, Burkholderia pseudomallei 7894, Burkholderia pseudomallei MSHR2543, Burkholderia pseudomallei MSHR491, Burkholderia pseudomallei 406e, Burkholderia pseudomallei 1026b, Burkholderia pseudomallei MSHR435, Burkholderia pseudomallei TSV44, Burkholderia pseudomallei TSV32, Burkholderia pseudomallei MSHR2138, Burkholderia sp. MSHR4018, Burkholderia sp. MSHR4009, Burkholderia sp. ABCPW 1, Burkholderia pseudomallei MSHR640, Burkholderia pseudomallei MSHR332, Burkholderia pseudomallei MSHR456, Burkholderia pseudomallei MSHR449, Burkholderia pseudomallei MSHR2990, Burkholderia pseudomallei MSHR1357, Burkholderia pseudomallei MSHR1029, Burkholderia pseudomallei MSHR303, Burkholderia pseudomallei MSHR684, Burkholderia pseudomallei MSHR733, Burkholderia pseudomallei MSHR2451, Burkholderia pseudomallei MSHR3016, Burkholderia pseudomallei MSHR4000, Burkholderia pseudomallei MSHR4303, Burkholderia pseudomallei MSHR3960, Burkholderia pseudomallei MSHR3951, Burkholderia pseudomallei MSHR3964, Burkholderia pseudomallei MSHR4375, Burkholderia pseudomallei MSHR4003, Burkholderia pseudomallei ABCPW 91, Burkholderia pseudomallei BDU 2, Burkholderia pseudomallei MSHR4012, Burkholderia pseudomallei MSHR4462, Burkholderia pseudomallei MSHR4300, Burkholderia pseudomallei MSHR4372, Burkholderia pseudomallei MSHR543, Burkholderia pseudomallei MSHR7498, Burkholderia pseudomallei MSHR5596, Burkholderia pseudomallei MSHR7500, Burkholderia pseudomallei MSHR4868, Burkholderia pseudomallei MSHR5613, Burkholderia pseudomallei MSHR5609, Burkholderia pseudomallei ABCPW 107, Burkholderia pseudomallei MSHR5492, Burkholderia pseudomallei MSHR5569, Burkholderia pseudomallei MSHR4378, Burkholderia pseudomallei MSHR7504, Burkholderia pseudomallei MSHR5608, Burkholderia sp. TSV202, Burkholderia pseudomallei MSHR3965, Burkholderia pseudomallei NAU35A-3, Burkholderia sp. BGK, Burkholderia sp. BGJ, Burkholderia pseudomallei HBPUB10303a, Burkholderia pseudomallei HBPUB10134a, Burkholderia pseudomallei MSHR5858, Burkholderia pseudomallei MSHR5848, Burkholderia pseudomallei MSHR5855, Burkholderia pseudomallei 576, Burkholderia pseudomallei MSHR6137, Burkholderia pseudomallei MSHR520, Burkholderia pseudomallei MSHR146, Burkholderia pseudomallei MSHR511, Burkholderia pseudomallei NCTC 13178, Burkholderia pseudomallei NAU20B-16, Burkholderia pseudomallei NCTC 13179, Burkholderia pseudomallei MSHR338, Burkholderia pseudomallei MSHR305, Burkholderia pseudomallei MSHR1043, Burkholderia pseudomallei BPC006, Burkholderia pseudomallei 354a, Burkholderia pseudomallei 354e, Burkholderia pseudomallei 1258b, Burkholderia pseudomallei 1258a, Burkholderia pseudomallei 1026a, Burkholderia pseudomallei 1710a, Burkholderia pseudomallei 1106b, Burkholderia pseudomallei MSHR346, Burkholderia pseudomallei Pakistan 9, Burkholderia pseudomallei 1655, Burkholderia pseudomallei S13, Burkholderia pseudomallei 305, Burkholderia pseudomallei 1106a, Burkholderia pseudomallei 668, Burkholderia pseudomallei 1710b Bacteria UP000032605, UP000029571, UP000033062, UP000029523, UP000032644, UP000032635, UP000032603, UP000032609, UP000032642, UP000032627, UP000030280, UP000030438, UP000030486, UP000030538, UP000030410, UP000030515, UP000030490, UP000030379, UP000030431, UP000030472, UP000030415, UP000030506, UP000030464, UP000030352, UP000030540, UP000030521, UP000030583, UP000030449, UP000030386, UP000030391, UP000030556, UP000030502, UP000030482, UP000030555, UP000030420, UP000030548, UP000030567, UP000030434, UP000030382, UP000030517, UP000030393, UP000030407, UP000030575, UP000030455, UP000030443, UP000030511, UP000030507, UP000030474, UP000030411, UP000030470, UP000030495, UP000030476, UP000030530, UP000030072, UP000029671, UP000029504, UP000029486, UP000029506, UP000029511, UP000027835, UP000029401, UP000019427, UP000027613, UP000027610, UP000027615, UP000027617, UP000027619, UP000027605, UP000019100, UP000015448, UP000011901, UP000010098, UP000004960, UP000004942, UP000004227, UP000005041, UP000006204, UP000001812, UP000007034, UP000002031, UP000005700, UP000002784, UP000002781, UP000004448, UP000006738, UP000002153, UP000002700 490656875, 53718925, 815842185, 806490944, 805605526, 780611740, 773040159, 772979654, 772968298, 772959551, 772953434, 772945415, 772942198, 772934200, 772899058, 772888574, 769543144, 760221661, 760216517, 760194123, 715120117, 715015343, 715010591, 714913103, 714858470, 714855447, 714843111, 714830091, 714823271, 714822195, 714821896, 714688171, 714655924, 714652963, 714650467, 714645076, 714605063, 714600365, 714590747, 714586898, 714582011, 714568693, 714557236, 714542956, 714539447, 714533376, 714532136, 714518808, 714504927, 714485376, 714476931, 714458633, 713020339, 705765634, 705757620, 705735859, 705729122, 705641756, 705592258, 705590840, 705578518, 705572667, 705563394, 705553916, 705475671, 705465117, 701274936, 701256379, 695185378, 694168975, 686977386, 686964156, 686953403, 686947300, 686941798, 686933912, 686927713, 686913961, 686897625, 686889469, 686880216, 686869513, 686861106, 686858331, 685799914, 685790600, 685777135, 685771163, 685767701, 685758453, 685742595, 685732448, 685728154, 685723124, 685718565, 685708606, 685701683, 685700116, 660627502, 589809251, 589302527, 575436407, 574601449, 568796545, 568789333, 556043801, 529457847, 526269825, 469644032, 403073745, 385659440, 385375974, 385371070, 385360084, 385358007, 385347051, 254218785, 242139996, 237503839, 225929310, 217393668, 184210816, 169653969, 157935978, 157806920, 134244860, 126226026, 126218664, 76578340, 814498737, 814489457, 814482218, 814476331, 814471470, 814465064, 814458461, 814453918, 814448463, 814441364, 814435334, 814429287, 814423935, 814417837, 814415205, 814406240, 814400186, 814394816, 814391104, 814382244, 814379298, 814370445, 814364635, 814358995, 814353025, 814347956, 814341708, 803169125, 803115178, 803051377, 803027041, 802999268, 802992487, 802987715, 802880930, 802870384, 802857291, 802829546, 802823291, 802817561, 802790821, 802781679, 802776825, 802763116, 802745288, 802735858, 802726628, 802718954, 802713366, 802052201, 801962724, 801880947, 801843233, 801819863, 801794164, 801781039, 801759190, 801748056, 801733661, 801728380, 801724854, 801716382, 801714418, 801704833, 801699096, 801693010, 801687771, 801681056, 801674746, 801667624, 801662231, 801656669, 801654601, 801648681, 801639478, 801634390, 801628787, 801622457, 801619057, 801610960, 801605255, 801354418, 801351524, 801259166, 800869325, 800858758, 800848925, 800837452, 800818091, 800809940, 800800661, 800784598, 664636968, 166228022, 166228021, 109895155, 81607985, 52209339 KKI77326.1, KKC12868.1, KKB69358.1, KJR94773.1, AJX62385.1, AJX39035.1, AJX95827.1, AJX27022.1, AJX88794.1, AJX82017.1, AJX79548.1, AJX23709.1, AJW92885.1, AJX07451.1, AJW52713.1, KIX67798.1, KIX62860.1, KIX40907.1, KGX79416.1, KGX56768.1, KGX52143.1, KGX41915.1, KGX25199.1, KGX22254.1, KGX09932.1, KGX04438.1, KGW97946.1, KGW96901.1, KGW96611.1, KGW77523.1, KGW61585.1, KGW58646.1, KGW56162.1, KGW50774.1, KGW35207.1, KGW30548.1, KGW21014.1, KGW17236.1, KGW12383.1, KGV99124.1, KGV87697.1, KGV73493.1, KGV69986.1, KGV63978.1, KGV62740.1, KGV49441.1, KGV35600.1, KGV23745.1, KGV15407.1, KGU97152.1, KGU76379.1, KGS98621.1, KGS94652.1, KGS80784.1, KGS74240.1, KGS67237.1, KGS54550.1, KGS53218.1, KGS41322.1, KGS35647.1, KGS26805.1, KGS17649.1, KGS05499.1, KGR95267.1, AIV79162.1, AIV85028.1, AIS87801.1, AIS46812.1, KGD54291.1, KGD41602.1, KGD31257.1, KGD25277.1, KGD19835.1, KGD12078.1, KGD05989.1, KGC92355.1, KGC76242.1, KGC68181.1, KGC59008.1, KGC48632.1, KGC40306.1, KGC37655.1, AIP81067.1, AIP71756.1, AIP58295.1, AIP52326.1, AIP48865.1, AIP39620.1, AIP23892.1, AIP13748.1, AIO15398.1, AIP10175.1, AIP05618.1, AIO95661.1, AIO88740.1, AIO87228.1, KEO69790.1, EXJ02274.1, AHK66658.1, AHG68711.1, AHG33817.1, AHE26989.1, AHE31832.1, AGZ28137.1, EQA89587.1, AGR72226.1, EMP76751.1, AFR15325.1, AFI66863.1, EIF80699.1, EIF76278.1, EIF66025.1, EIF64037.1, EIF53721.1, EET08169.1, EES26398.1, ACQ96157.1, EEH25331.1, EEC33689.1, EDU07859.1, EDS86662.1, EDO91648.1, EDO84090.1, EBA44957.1, ABN89566.1, ABN82170.1, ABA47815.1 WP_004521865.1, YP_107911.1 A3NTK3, Q3JU20, A3N7W7, Q63VF5 THIC_BURP0, THIC_BURP1, THIC_BURP6, THIC_BURPS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2365568, 4313987, 4509065, 4557582, 2661903, 1847504, 4541330, 6368404, 741206, 4533015, 4492379, 1965020, 4524763, 1065645, 2380242, 4549427, 7547002, 2385915, 4500797 fig|1247713.3.peg.1708, fig|272560.3.peg.3639, fig|1262664.3.peg.2513, fig|1086036.3.peg.1903, fig|557724.3.peg.5015, fig|357348.6.peg.1350, fig|425067.3.peg.6531, fig|1290415.3.peg.2030, fig|1290418.3.peg.2421, fig|1229785.3.peg.1442, fig|1289589.3.peg.1546, fig|320371.3.peg.3096, fig|331978.3.peg.2314, fig|1086034.3.peg.2277, fig|331109.3.peg.4324, fig|1290417.3.peg.5625, fig|360118.4.peg.2595, fig|320373.3.peg.3777, fig|1085027.3.peg.6208, fig|1290414.3.peg.2398, fig|595498.3.peg.5253, fig|357347.4.peg.1584, fig|1086032.3.peg.2068, fig|1290419.3.peg.2610, fig|536230.4.peg.1313, fig|320372.3.peg.4259, fig|1086033.3.peg.2178, fig|320374.3.peg.2062, fig|884204.3.peg.2482, fig|1290416.3.peg.916 642 643 yes 437634 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 482957 Burkholderia lata Bacteria UP000036521 499670763, 77966547, 109895156 ABB07927.1 WP_011351497.1 Q39HY9 THIC_BURL3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1058706 fig|269483.3.peg.5433 642 643 yes 437635 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 57975, 1249660, 1249666, 1249665, 1250339, 271848, 1249667, 1249662, 1241582, 1249663 Burkholderia thailandensis, Burkholderia thailandensis 2002721643, Burkholderia thailandensis Phuket 4W-1, Burkholderia thailandensis E254, Burkholderia thailandensis MSMB59, Burkholderia thailandensis E264, Burkholderia thailandensis USAMRU Malaysia #20, Burkholderia thailandensis E444, Burkholderia thailandensis 2002721723, Burkholderia thailandensis H0587 Bacteria UP000055962, UP000032610, UP000032082, UP000029820, UP000029668, UP000001930, UP000027140, UP000019268, UP000019266, UP000019264 497591985, 772989177, 757941024, 695924530, 695179550, 685781759, 685745850, 655536735, 584105731, 584102545, 584091974, 83653358, 109895157 AJX97541.1, KIS56755.1, AIT21733.1, AIS95333.1, AIP62918.1, AIP27022.1, AIC85911.1, AHI77349.1, AHI74181.1, AHI63554.1, ABC37421.1 WP_009906169.1 Q2SUP3 THIC_BURTA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 4481250, 4452962, 1079093 fig|271848.6.peg.5722, fig|441164.3.peg.5500, fig|441165.3.peg.5420 647 648 yes 437636 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 129958, 246194 Carboxydothermus hydrogenoformans, Carboxydothermus hydrogenoformans Z-2901 Bacteria UP000002706 499662943, 77995831, 109895158 ABB14730.1 WP_011343677.1 Q3AE33 THIC_CARHZ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1080996 fig|246194.3.peg.780 429 429 yes 437637 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 337090, 340177 Chlorobium chlorochromatii, Chlorobium chlorochromatii CaD3 Bacteria UP000002708 499680694, 78170559, 109895159 ABB27655.1 WP_011361428.1 Q3ATM0 THIC_CHLCH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1084306 fig|340177.11.peg.399 531 531 yes 437638 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28229, 167879 Colwellia psychrerythraea, Colwellia psychrerythraea 34H Bacteria UP000029843, UP000000547 499352173, 71147836, 109895160 AAZ28309.1 WP_011041124.1 Q48A96 THIC_COLP3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 838057 fig|167879.3.peg.309 646 658 yes 437639 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 38289, 306537 Corynebacterium jeikeium, Corynebacterium jeikeium K411 Bacteria UP000000545 499592717, 109895161, 68263529 WP_011273451.1 Q4JVZ0 THIC_CORJK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 843759 fig|306537.10.peg.866 620 641 yes 437640 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 259537, 159087 Dechloromonas aromatica, Dechloromonas aromatica RCB Bacteria UP000000550 499608910, 71849153, 109895162 AAZ48649.1 WP_011289644.1 Q478T2 THIC_DECAR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 581421 fig|159087.4.peg.3009 638 638 yes 437641 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 61435, 243164 Dehalococcoides ethenogenes, Dehalococcoides ethenogenes 195 Bacteria UP000054393, UP000008289 499238968, 57224877, 109895163 AAW39934.1 WP_010936508.1 Q3Z8E2 THIC_DEHM1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 845834 fig|243164.10.peg.739 430 431 yes 437642 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 61435, 633145, 255470 Dehalococcoides ethenogenes, Dehalococcoides sp. GT, Dehalococcoides sp. CBDB1 Bacteria UP000054393, UP000002635, UP000000433 499628525, 288946331, 109895164, 73660301 ADC74028.1 WP_011309259.1 Q3ZXE1 THIC_DEHMC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1086613, 10378366 fig|633145.4.peg.636, fig|255470.3.peg.25 430 431 yes 437643 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 269484 Ehrlichia canis str. Jake Bacteria UP000000435 72394048, 109895165 AAZ68325.1 Q3YSI0 THIC_EHRCJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1087773 fig|269484.4.peg.358 559 565 yes 437644 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 945, 1249650, 1249656, 1249655, 1249654, 1249653, 1249652, 1249651, 205920 Ehrlichia chaffeensis, Ehrlichia chaffeensis str. West Paces, Ehrlichia chaffeensis str. Wakulla, Ehrlichia chaffeensis str. Saint Vincent, Ehrlichia chaffeensis str. Osceola, Ehrlichia chaffeensis str. Liberty, Ehrlichia chaffeensis str. Jax, Ehrlichia chaffeensis str. Heartland, Ehrlichia chaffeensis str. Arkansas Bacteria UP000023670, UP000023608, UP000023642, UP000023632, UP000023620, UP000023611, UP000023753, UP000008320 499772084, 612500400, 612500035, 612498562, 612498222, 612496565, 612495577, 612494012, 88599998, 109895166 AHX10237.1, AHX09873.1, AHX08401.1, AHX08062.1, AHX06406.1, AHX05419.1, AHX03856.1, ABD45467.1 WP_011452818.1 Q2GG37 THIC_EHRCR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1230197 fig|205920.11.peg.696 554 554 yes 437645 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1525, 264732 Moorella thermoacetica, Moorella thermoacetica ATCC 39073 Bacteria UP000067720, UP000007053 499712490, 83590558, 83573472, 109895147 ABC20024.1 WP_011393224.1, YP_430567.1 Q2RHR5 THIC2_MOOTA Phosphomethylpyrimidine synthase 2 {ECO:0000255|HAMAP-Rule:MF_00089} 1112687 fig|264732.11.peg.1865 420 426 yes 437646 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 377431 Chlorobium ferrooxidans DSM 13031 Bacteria UP000004162 110340608 EAT59088.1 fig|377431.3.peg.1061 544 544 yes 437647 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 266835 Mesorhizobium loti MAFF303099 Bacteria UP000000552 29337121, 14025579 Q98AZ3 THIC_RHILO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 87191 fig|266835.1.peg.4496 606 619 yes 437648 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 313625 Synechococcus sp. BL107 Bacteria UP000004390 116065292 EAU71050.1 446 452 yes 437649 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 197, 1365659, 1437113, 1436885, 1338035, 889234, 889232, 889231, 889215, 889223, 889222, 889253, 889221, 889252, 889219, 889243, 889217, 889240, 889213, 354242 Campylobacter jejuni, Campylobacter jejuni Cj2, Campylobacter jejuni subsp. jejuni 81-176-UMCW9, Campylobacter jejuni subsp. jejuni 81-176-UMCW7, Campylobacter jejuni 32488, Campylobacter jejuni subsp. jejuni 1893, Campylobacter jejuni subsp. jejuni 1798, Campylobacter jejuni subsp. jejuni 1577, Campylobacter jejuni subsp. jejuni 140-16, Campylobacter jejuni subsp. jejuni 1997-7, Campylobacter jejuni subsp. jejuni 1997-4, Campylobacter jejuni subsp. jejuni 2008-988, Campylobacter jejuni subsp. jejuni 1997-1, Campylobacter jejuni subsp. jejuni 2008-872, Campylobacter jejuni subsp. jejuni 86605, Campylobacter jejuni subsp. jejuni LMG 23264, Campylobacter jejuni subsp. jejuni 60004, Campylobacter jejuni subsp. jejuni LMG 23218, Campylobacter jejuni subsp. jejuni 129-258, Campylobacter jejuni subsp. jejuni 81-176 Bacteria UP000065538, UP000025176, UP000018844, UP000018831, UP000014942, UP000003788, UP000004190, UP000003570, UP000003003, UP000003154, UP000006240, UP000003238, UP000003683, UP000005327, UP000005721, UP000005196, UP000003051, UP000003420, UP000004447, UP000000646 488957722, 631613324, 568401225, 567319230, 523831305, 380670582, 380663235, 380662385, 380658648, 380643533, 380642623, 380636105, 380633898, 380632796, 380616925, 380611117, 380607518, 380601732, 380596949, 87250436, 166228027 KDA29285.1, ETN90680.1, ETJ84324.1, AGQ95173.1, EIB85830.1, EIB78889.1, EIB78128.1, EIB74653.1, EIB60756.1, EIB59883.1, EIB53842.1, EIB51817.1, EIB50846.1, EIB36112.1, EIB30675.1, EIB27375.1, EIB22039.1, EIB17622.1, EAQ73394.1 WP_002868797.1 A1VYG9 THIC_CAMJJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5989082, 1956339, 4072510 fig|889231.3.peg.1682, fig|889232.3.peg.945, fig|889217.3.peg.765, fig|889253.3.peg.1090, fig|889215.3.peg.1015, fig|889243.3.peg.534, fig|889219.3.peg.1012, fig|889240.3.peg.21, fig|889213.3.peg.192, fig|889252.3.peg.170, fig|889221.3.peg.908, fig|889222.3.peg.717, fig|885274.3.peg.853, fig|889223.3.peg.705, fig|885273.3.peg.818, fig|354242.16.peg.493, fig|889234.3.peg.21 430 430 yes 437650 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 334543, 259536 Psychrobacter arcticus, Psychrobacter arcticus 273-4 Bacteria UP000000546 499598665, 71037652, 109895182 AAZ17960.1 WP_011279399.1 Q4FVJ8 THIC_PSYA2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 887655 fig|259536.19.peg.102 666 691 yes 437651 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 330922, 335284 Psychrobacter cryohalolentis, Psychrobacter cryohalolentis K5 Bacteria UP000002425 499831734, 92392602, 109895183 ABE73877.1 WP_011512468.1 Q1QEM6 THIC_PSYCK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1899759 fig|335284.3.peg.669 604 628 yes 437652 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 248026, 264198 Cupriavidus pinatubonensis, Ralstonia eutropha JMP134 Bacteria UP000002697 499615661, 72117324, 109895184 AAZ59587.1 WP_011296395.1 Q476U6 THIC_CUPPJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 890656 fig|264198.3.peg.717 624 626 yes 437653 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 29449, 347834 Rhizobium etli, Rhizobium etli CFN 42 Bacteria UP000001936 499746812, 86284063, 109895185 ABC93124.1 WP_011427546.1 Q2K206 THIC_RHIEC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1268730 fig|347834.17.peg.4915 601 610 yes 437654 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 192843, 338969 Albidiferax ferrireducens, Rhodoferax ferrireducens T118 Bacteria UP000008332 499783271, 89345234, 109895186 ABD69437.1 WP_011464005.1 Q21XR6 THIC_RHOFT Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1272057 fig|338969.11.peg.2029 621 624 yes 437655 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1076, 316058 Rhodopseudomonas palustris, Rhodopseudomonas palustris HaA2 Bacteria UP000032515, UP000008809 499760116, 86572105, 109895187 ABD06662.1 WP_011440850.1 Q2IYP8 THIC_RHOP2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1281626 fig|316058.11.peg.2050 635 646 yes 437656 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1076, 316056 Rhodopseudomonas palustris, Rhodopseudomonas palustris BisB18 Bacteria UP000032515, UP000001948 499791881, 90105679, 109895188 ABD87716.1 WP_011472615.1 Q216H0 THIC_RHOPB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1276822 fig|316056.14.peg.2137 698 709 yes 437657 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 243277, 666, 686, 1343738, 1095638, 1095658, 1095642, 1095655, 1095650, 1095639, 1095643, 1095656, 1095648, 1095647, 1095646, 1095641, 1095640, 1095654, 1095653, 1095652, 1095651, 1095644, 1095660, 1095645, 1095661, 1224154, 991936, 991988, 991931, 1000953, 991985, 991983, 991982, 991981, 991980, 1236549, 992008, 992007, 1000952, 991958, 992006, 991987, 991968, 991951, 991924, 1000951, 991996, 991994, 991993, 991992, 991962, 991960, 991995, 991990, 992003, 991963, 991976, 991974, 991932, 991940, 991928, 991927, 991929, 991925, 991926, 991923, 1134456, 914149, 991966, 991942, 991957, 991938, 991956, 991955, 991954, 991933, 991952, 991953, 991950, 991959, 991989, 991961, 991965, 991984, 991935, 991930, 412967, 675808, 675807, 661513, 345072, 593588, 593587, 417400, 593589, 345073, 579112, 417399, 345076, 412614, 1420885 Vibrio cholerae O1 biovar El Tor str. N16961, Vibrio cholerae, Vibrio cholerae O1 biovar El Tor, Vibrio cholerae 2012EL-1759, Vibrio cholerae O1 str. PCS-022, Vibrio cholerae O1 str. NHCC-010F, Vibrio cholerae O1 str. Nep-21106, Vibrio cholerae O1 str. NHCC-004A, Vibrio cholerae O1 str. EM-1727, Vibrio cholerae O1 str. PCS-023, Vibrio cholerae O1 str. Nep-21113, Vibrio cholerae O1 str. NHCC-006C, Vibrio cholerae O1 str. EM-1626, Vibrio cholerae O1 str. EM-1546, Vibrio cholerae O1 str. EM-1536, Vibrio cholerae O1 str. EDC-022, Vibrio cholerae O1 str. EDC-020, Vibrio cholerae O1 str. EC-0051, Vibrio cholerae O1 str. EC-0027, Vibrio cholerae O1 str. EC-0012, Vibrio cholerae O1 str. EC-0009, Vibrio cholerae O1 str. AG-8040, Vibrio cholerae O1 str. 95412, Vibrio cholerae O1 str. AG-7404, Vibrio cholerae O1 str. 116059, Vibrio cholerae O1 str. Inaba G4222, Vibrio cholerae HC-81A1, Vibrio cholerae HC-80A1, Vibrio cholerae HC-7A1, Vibrio cholerae HC-72A2, Vibrio cholerae HC-71A1, Vibrio cholerae HC-68A1, Vibrio cholerae HC-67A1, Vibrio cholerae HC-65A1, Vibrio cholerae HC-64A1, Vibrio cholerae 4260B, Vibrio cholerae HC-69A1, Vibrio cholerae HC-62B1, Vibrio cholerae HC-17A2, Vibrio cholerae HC-37A1, Vibrio cholerae HC-62A1, Vibrio cholerae HC-77A1, Vibrio cholerae HC-50A2, Vibrio cholerae HC-17A1, Vibrio cholerae CP1033(6), Vibrio cholerae HC-81A2, Vibrio cholerae CP1050, Vibrio cholerae CP1044(17), Vibrio cholerae CP1040, Vibrio cholerae CP1037(10), Vibrio cholerae HC-41A1, Vibrio cholerae HC-39A1, Vibrio cholerae CP1047, Vibrio cholerae CP1030(3), Vibrio cholerae HC-47A1, Vibrio cholerae HC-42A1, Vibrio cholerae HC-57A2, Vibrio cholerae HC-56A2, Vibrio cholerae HC-20A2, Vibrio cholerae HC-46A1, Vibrio cholerae CP1046(19), Vibrio cholerae CP1042(15), Vibrio cholerae CP1048(21), Vibrio cholerae CP1038(11), Vibrio cholerae CP1041(14), Vibrio cholerae CP1032(5), Vibrio cholerae IEC224, Vibrio cholerae O1 str. 2010EL-1786, Vibrio cholerae HC-48B2, Vibrio cholerae HC-61A1, Vibrio cholerae HC-33A2, Vibrio cholerae HC-43A1, Vibrio cholerae HC-32A1, Vibrio cholerae HC-28A1, Vibrio cholerae HC-22A1, Vibrio cholerae HC-23A1, Vibrio cholerae HC-19A1, Vibrio cholerae HC-21A1, Vibrio cholerae HC-06A1, Vibrio cholerae HC-38A1, Vibrio cholerae HFU-02, Vibrio cholerae HC-40A1, Vibrio cholerae HC-48A1, Vibrio cholerae HC-70A1, Vibrio cholerae HC-49A2, Vibrio cholerae HCUF01, Vibrio cholerae MAK 757, Vibrio cholerae INDRE 91/1, Vibrio cholerae RC27, Vibrio cholerae CIRS101, Vibrio cholerae MO10, Vibrio cholerae MJ-1236, Vibrio cholerae BX 330286, Vibrio cholerae B33, Vibrio cholerae RC9, Vibrio cholerae O395, Vibrio cholerae M66-2, Vibrio cholerae NCTC 8457, Vibrio cholerae V52, Vibrio cholerae 2740-80, Vibrio cholerae MS6 Bacteria UP000000584 UP000000584, UP000028983, UP000029298, UP000028106, UP000023029, UP000012130, UP000012151, UP000012107, UP000012100, UP000012157, UP000012111, UP000012142, UP000012103, UP000012091, UP000012136, UP000012087, UP000012113, UP000012132, UP000012141, UP000012143, UP000012161, UP000012116, UP000012124, UP000012114, UP000012109, UP000011647, UP000010430, UP000010435, UP000010413, UP000010431, UP000010446, UP000010450, UP000010416, UP000010463, UP000010464, UP000010957, UP000008364, UP000008362, UP000008485, UP000008368, UP000007980, UP000007986, UP000007836, UP000007835, UP000007972, UP000007559, UP000007367, UP000006777, UP000007371, UP000006783, UP000007560, UP000007130, UP000002689, UP000008943, UP000001076, UP000008753, UP000002688, UP000001609, UP000006104, UP000008951, UP000008760, UP000002687, UP000008752, UP000001082, UP000002078, UP000002470, UP000010113, UP000006802, UP000004984, UP000004858, UP000005180, UP000005846, UP000003534, UP000004214, UP000004717, UP000004965, UP000003797, UP000004583, UP000004275, UP000003870, UP000005161, UP000003200, UP000005570, UP000004542, UP000003702, UP000003537, UP000004697, UP000004257, UP000004865, UP000004298, UP000004687, UP000001618, UP000004771, UP000002816, UP000002952, UP000001630, UP000001217, UP000003998, UP000005193, UP000003017, UP000031626 15640093, 445993254, 861212898, 818226490, 818216973, 818216324, 818216081, 788592676, 785752825, 769094682, 769089779, 769086905, 725528976, 725525703, 695933555, 669393727, 669373638, 669361236, 657851589, 657845443, 657321278, 585140857, 469760023, 469754041, 469747626, 469745575, 469732683, 469731825, 469730421, 469729083, 469720897, 469715704, 469715613, 469709222, 469703629, 469700949, 469700848, 469693063, 469692873, 469686421, 469683499, 469671961, 448265882, 443467833, 443462987, 443460112, 443451808, 443448772, 443444909, 443441098, 443437264, 443433425, 439972436, 408882327, 408876298, 408850456, 408850125, 408661154, 408660331, 408645180, 408628506, 408612512, 408058319, 408047764, 408045991, 408038808, 408037857, 408018427, 408011291, 395980145, 395979709, 395977181, 395967852, 395965371, 395965145, 395948067, 395939145, 395936293, 395935904, 395929156, 395926407, 395925266, 395924124, 378793475, 356647869, 356456801, 356455603, 356451227, 356448571, 356445516, 356438822, 356435938, 356434561, 356427750, 356423601, 356422876, 341649201, 341641932, 341628670, 341628325, 341626790, 340046071, 340045745, 297540196, 262030892, 262024336, 255738460, 254847152, 229369275, 229354618, 229354090, 229346150, 227011937, 227008185, 146317309, 126520341, 126511232, 121629928, 121548087, 9654456, 657187483, 254784171, 172047506, 24638287 AKO76284.1, KKP19175.1, KKP09761.1, KKP09120.1, KKP08879.1, KJW15314.1, AJZ98613.1, KJJ56975.1, KJJ53856.1, KJJ51085.1, KHE20997.1, KHE17822.1, AIT30755.1, KFE18612.1, KFE01224.1, KFD90233.1, KEH81218.1, KEH77893.1, KEH06632.1, EWM34229.1, EMQ72061.1, EMQ66252.1, EMQ60155.1, EMQ58163.1, EMQ46908.1, EMQ46118.1, EMQ44793.1, EMQ43498.1, EMQ35663.1, EMQ30659.1, EMQ30569.1, EMQ24352.1, EMQ18984.1, EMQ16423.1, EMQ16329.1, EMQ08729.1, EMQ08553.1, EMQ02268.1, EMP99471.1, EMP88429.1, EMB03115.1, ELT42487.1, ELT34002.1, ELT27501.1, ELT12050.1, ELT05385.1, ELS98165.1, ELS90765.1, ELS83360.1, ELS75931.1, ELP48722.1, EKM21160.1, EKM15426.1, EKL90411.1, EKL90101.1, EKL32146.1, EKL31349.1, EKL16844.1, EKL01242.1, EKK85847.1, EKG93128.1, EKG83323.1, EKG81719.1, EKG75133.1, EKG74228.1, EKG55878.1, EKG49112.1, EJH89442.1, EJH89044.1, EJH86602.1, EJH77888.1, EJH75544.1, EJH75327.1, EJH58721.1, EJH49828.1, EJH47018.1, EJH46638.1, EJH39907.1, EJH37190.1, EJH36066.1, EJH34933.1, AFC56946.1, AET27924.1, EHI09382.1, EHI08244.1, EHI03922.1, EHI01334.1, EHH98319.1, EHH91824.1, EHH89073.1, EHH87738.1, EHH80990.1, EHH77042.1, EHH76339.1, EGS73195.1, EGS66443.1, EGS53888.1, EGS53583.1, EGS52146.1, EGR07005.1, EGR06684.1, EFH76257.1, EEY49522.1, EEY43026.1, EET93850.1, EET25566.1, ACQ59698.1, EEO19540.1, EEO19023.1, EEO11122.1, ACP08147.1, ACP04397.1, ABQ21848.1, EAZ77564.1, EAZ73826.1, EAX62340.1, EAX58162.1, AAF93239.1 NP_229720.1, WP_000071109.1 A5F4D2, Q9KVS8, C3LPQ3 THIC_VIBC3, THIC_VIBCH, THIC_VIBCM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7652736, 4125761, 52676, 3062117, 2508007, 4161515, 2495884, 6958432, 7695640, 4157468 fig|593589.3.peg.1050, fig|1095647.3.peg.95, fig|991924.3.peg.483, fig|992003.3.peg.946, fig|991965.6.peg.952, fig|992007.3.peg.811, fig|345076.11.peg.1753, fig|991987.3.peg.983, fig|991988.4.peg.1038, fig|991960.3.peg.926, fig|1095648.3.peg.81, fig|925769.13.peg.89, fig|991957.4.peg.91, fig|991984.6.peg.893, fig|991954.4.peg.1038, fig|991951.3.peg.146, fig|991982.4.peg.80, fig|243277.1.peg.61, fig|991992.3.peg.541, fig|1000952.3.peg.619, fig|1225783.3.peg.1415, fig|991950.4.peg.771, fig|991963.3.peg.79, fig|1095644.3.peg.57, fig|991994.3.peg.1075, fig|1095655.3.peg.464, fig|1095654.3.peg.1192, fig|417400.10.peg.5388, fig|991926.3.peg.380, fig|1095651.3.peg.790, fig|1147127.3.peg.2523, fig|991930.6.peg.90, fig|675808.3.peg.620, fig|991995.3.peg.79, fig|991958.3.peg.967, fig|991996.3.peg.1063, fig|1095652.3.peg.80, fig|991931.4.peg.113, fig|992008.3.peg.79, fig|991940.3.peg.3739, fig|991962.3.peg.81, fig|991961.6.peg.893, fig|675807.3.peg.459, fig|991956.4.peg.79, fig|661513.3.peg.282, fig|991985.4.peg.73, fig|579112.3.peg.59, fig|991981.4.peg.82, fig|914149.18.peg.88, fig|1095645.3.peg.959, fig|991955.4.peg.769, fig|1095650.3.peg.1012, fig|991932.3.peg.94, fig|1095661.3.peg.943, fig|991927.3.peg.82, fig|1095653.3.peg.797, fig|593588.5.peg.1547, fig|991929.3.peg.3591, fig|1095640.3.peg.95, fig|991923.3.peg.200, fig|991928.3.peg.285, fig|991925.3.peg.82, fig|412967.3.peg.1881, fig|1095656.3.peg.80, fig|1095642.3.peg.748, fig|1000951.3.peg.1051, fig|593587.4.peg.3449, fig|1095658.3.peg.80, fig|1095646.3.peg.1088, fig|1095643.3.peg.80, fig|991952.4.peg.80, fig|991974.3.peg.799, fig|1095639.3.peg.3041, fig|345073.12.peg.3467, fig|991989.6.peg.78, fig|1258564.3.peg.1852, fig|991990.3.peg.79, fig|991959.6.peg.87, fig|1134456.3.peg.59, fig|991942.6.peg.2, fig|991933.6.peg.2, fig|417399.11.peg.1364, fig|925768.13.peg.99, fig|991953.4.peg.1096, fig|991936.4.peg.82, fig|991993.3.peg.1056, fig|412614.3.peg.1724, fig|991938.6.peg.186, fig|991983.4.peg.90, fig|1236549.3.peg.3398, fig|991935.7.peg.93, fig|991976.3.peg.1064, fig|991980.4.peg.81, fig|1095660.3.peg.81, fig|991966.4.peg.909, fig|992006.3.peg.78, fig|1000953.4.peg.789, fig|991968.3.peg.798, fig|1225782.3.peg.1159, fig|345072.13.peg.3404, fig|1095641.3.peg.100 639 645 yes 437658 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86304, 203122 Saccharophagus degradans, Saccharophagus degradans 2-40 Bacteria UP000001947 499786123, 89949618, 109895190 ABD79633.1 WP_011466857.1 Q21NU6 THIC_SACD2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3820727 fig|203122.12.peg.369 635 638 yes 437659 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 543, 621, 562, 623, 766155, 766140, 754091, 766139, 945360, 300268 Shigella boydii, Escherichia coli, Shigella flexneri, Shigella flexneri 1485-80, Shigella boydii 4444-74, Shigella flexneri CCH060, Shigella boydii 3594-74, Shigella flexneri CDC 796-83, Shigella boydii Sb227 Bacteria UP000035613, UP000036210, UP000029282, UP000006046, UP000004199, UP000005406, UP000003376, UP000003302, UP000007067 447199683, 827432422, 763501709, 738562457, 404335977, 391271739, 391246732, 332092321, 320185966, 81247747, 109895191 AKI68981.1, KIZ70514.1, KHQ65940.1, EJZ62442.1, EIQ30606.1, EIQ05991.1, EGI97396.1, EFW60714.1, ABB68455.1 WP_001276939.1 Q31U03 THIC_SHIBS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1153377 fig|945360.3.peg.1838, fig|754091.3.peg.4093, fig|300268.10.peg.4752, fig|766140.3.peg.4723, fig|766139.3.peg.2995, fig|766155.3.peg.4057, fig|623.7.peg.2501 626 631 yes 437660 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 196, 1240980, 360106 Campylobacter fetus, Campylobacter fetus subsp. fetus 04/554, Campylobacter fetus subsp. fetus 82-40 Bacteria UP000031165, UP000029484, UP000000760 500051888, 706088575, 691215063, 118414514, 166228024 KGT36275.1, AIR78356.1, ABK82934.1 WP_011731805.1 A0RN29 THIC_CAMFF Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1982441 fig|360106.5.peg.397 449 450 yes 437661 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 624, 766164, 300269 Shigella sonnei, Shigella sonnei 4822-66, Shigella sonnei Ss046 Bacteria UP000054188, UP000006033, UP000002529 447199675, 721551895, 391291409, 73857965, 109895193 KGY95233.1, EIQ49811.1, AAZ90672.1 WP_001276931.1 Q3YUZ0 THIC_SHISS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1162884 fig|766164.3.peg.4330, fig|300269.11.peg.4784 626 631 yes 437662 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 316277, 56780 Syntrophus aciditrophicus, Syntrophus aciditrophicus SB Bacteria UP000001933 499736441, 85722203, 109895194 ABC77146.1 WP_011417175.1 Q2LSU0 THIC_SYNAS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1737554 fig|56780.10.peg.1252 426 427 yes 437663 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 321327 Synechococcus sp. JA-3-3Ab Bacteria UP000008818 499748202, 86553286, 109895195 ABC98244.1 WP_011428936.1 Q2JY68 THIC_SYNJA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1304280 fig|321327.20.peg.11 452 455 yes 437664 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 36873, 266265 Burkholderia xenovorans, Burkholderia xenovorans LB400 Bacteria UP000029421 499808343, 685750773, 91688305, 123168284 AIP31943.1, ABE31505.1 WP_011489077.1 Q13WN4 THIC_PARXL Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3361508 fig|36873.1.peg.5696, fig|266265.5.peg.3116 642 643 yes 437665 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1129, 1350461, 1140 Synechococcus sp. UTEX 2973, Synechococcus elongatus PCC 7942 Bacteria UP000031358, UP000002717 499697127, 745803090, 81168786, 109895197 AJD58357.1, ABB57126.1 WP_011377861.1 Q31P93 THIC_SYNE7 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1174648 fig|1140.3.peg.656 452 456 yes 437666 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 316279 Synechococcus sp. CC9902 Bacteria UP000002712 499678272, 78168045, 109895198 ABB25142.1 WP_011359006.1 Q3B0I6 THIC_SYNS9 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1171227 fig|316279.3.peg.310 464 466 yes 437667 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 110662 Synechococcus sp. CC9605 Bacteria UP000002711 78196134, 109895199 ABB33899.1 Q3AND3 THIC_SYNSC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1168431 fig|110662.3.peg.613 476 484 yes 437668 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 317025 Thiomicrospira crunogena XCL-2 Bacteria UP000002713 78362779, 109895200 ABB40744.1 Q31JC9 THIC_THICR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1176342 fig|317025.3.peg.100 621 630 yes 437669 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 36861, 292415 Thiobacillus denitrificans, Thiobacillus denitrificans ATCC 25259 Bacteria UP000064243, UP000008291 499632472, 74058207, 109895201 AAZ98647.1 WP_011313206.1 Q3SFG3 THIC_THIDA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3418081 fig|292415.3.peg.2767 648 652 yes 437670 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 39766, 326298 Sulfurimonas denitrificans, Sulfurimonas denitrificans DSM 1251 Bacteria UP000002714 499692381, 78498223, 109895202 ABB44763.1 WP_011373115.1 Q30QG8 THIC_SULDN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1179984 fig|326298.3.peg.889 457 460 yes 437671 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 338, 456327, 316273 Xanthomonas euvesicatoria, Xanthomonas campestris pv. vesicatoria str. 85-10 Bacteria UP000035505, UP000007069 499667780, 821848155, 821842364, 821833246, 821820956, 821819069, 821806392, 821801624, 821796317, 821791113, 821788739, 821779354, 821730561, 733449494, 733440753, 109895203, 78037561 KLB99990.1, KLB94257.1, KLB85446.1, KLB73573.1, KLB71732.1, KLB59456.1, KLB54777.1, KLB49901.1, KLB45169.1, KLB42876.1, KLB33805.1, KLA87431.1, KHL66752.1, KHL58476.1 WP_011348514.1 Q3BPK7 THIC_XANC5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1184475 fig|316273.10.peg.3850 624 625 yes 437672 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 292414 Ruegeria sp. TM1040 Bacteria UP000000636 499858644, 99038174, 122397732 ABF64786.1 WP_011539378.1 Q1GEY0 THIC_RUEST Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3414346 fig|292414.1.peg.425, fig|292414.10.peg.2979 600 608 yes 437673 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 344736, 314265 Pelagibaca bermudensis, Pelagibaca bermudensis HTCC2601 Bacteria UP000006230 495075164, 114540519 EAU43597.1 WP_007799989.1 fig|314265.3.peg.3051 591 594 yes 437674 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 62928 Azoarcus sp. BH72 Bacteria UP000002588 500088561, 166228010, 119669544 WP_011764574.1 A1K3Q2 THIC_AZOSB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1740465 fig|62928.7.peg.854 638 638 yes 437675 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2224, 349307 Methanosaeta thermophila, Methanosaeta thermophila PT Archaea UP000000674 500015630, 116754477, 116665928 ABK14955.1 WP_011696348.1, YP_843595.1 A0B8D1 A0B8D1_METTP 1934895 fig|349307.9.peg.1152 420 427 yes 437676 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 80864, 680496, 232721 Diaphorobacter sp. J5-51, Acidovorax sp. JS42 Bacteria UP000036032, UP000000645 500130750, 829485801, 120608032, 166228008 KLR57768.1, ABM43772.1 WP_011806755.1 A1WBZ7 THIC_ACISJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2218101 fig|232721.5.peg.3663 609 614 yes 437677 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 326424 Frankia alni ACN14a Bacteria UP000000657 111147806 fig|326424.13.peg.718 594 656 yes 437678 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 59610, 349161 Desulfotomaculum reducens, Desulfotomaculum reducens MI-1 Bacteria UP000001556 500208985, 134053423, 172044346 ABO51394.1 WP_011879187.1 A4J8J1 THIC_DESRM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3512418 fig|349161.4.peg.2842 432 432 yes 437679 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 74426, 411903 Collinsella aerofaciens, Collinsella aerofaciens ATCC 25986 Bacteria UP000002979 493276368, 133776755 EBA40575.1 WP_006234165.1 fig|411903.6.peg.220 443 444 yes 437680 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1219, 167542 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9515 Bacteria UP000001589 500145088, 123201398, 166228055 ABM73006.1 WP_011821091.1 A2BYZ5 THIC_PROM5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1213781 fig|167542.6.peg.1843 452 456 yes 437681 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1206, 203124 Trichodesmium erythraeum, Trichodesmium erythraeum IMS101 Bacteria UP000008878 499931305, 110167135, 123352244 ABG51675.1 WP_011612039.1 Q111Z9 THIC_TRIEI Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2185435 fig|203124.1.peg.1264 485 486 yes 437682 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 266779 Chelativorans sp. BNC1 Bacteria UP000001820 499901152, 110285886 ABG63945.1 WP_011581886.1 fig|266779.1.peg.1530 604 608 yes 437683 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 266, 318586 Paracoccus denitrificans, Paracoccus denitrificans PD1222 Bacteria UP000000361 500073205, 119376264, 166228051 ABL71028.1 WP_011749218.1 A1B684 THIC_PARDP Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1840980 fig|318586.4.peg.2776 591 599 yes 437684 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 290399 Arthrobacter sp. FB24 Bacteria UP000000754 500011611, 116611142 ABK03866.1 WP_011692329.1 fig|290399.4.peg.2861 594 626 yes 437685 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 228, 326442 Pseudoalteromonas haloplanktis, Pseudoalteromonas haloplanktis TAC125 Bacteria UP000006843 499646455, 109895180, 76874355 WP_011327189.1 Q3IFN9 THIC_PSEHT Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1129182 fig|326442.4.peg.462 645 650 yes 437686 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 156578 Alteromonadales bacterium TW-7 Bacteria UP000004833 493845006, 119447386 EAW28654.1 WP_006792066.1 fig|156578.3.peg.903 645 650 yes 437687 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 294, 205922 Pseudomonas fluorescens, Pseudomonas fluorescens Pf0-1 Bacteria UP000060991, UP000002704 499651423, 747115826, 77380723, 109895181 KIF62400.1, ABA72236.1 WP_011332157.1 Q3KJ20 THIC_PSEPF Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 10485899 fig|205922.3.peg.2156 628 629 yes 437688 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 70799, 313624 Nodularia spumigena, Nodularia spumigena CCY9414 Bacteria UP000003307 493211917, 585121949, 119464216 AHJ28891.1, EAW45135.1 WP_006196684.1 fig|313624.3.peg.2393 455 457 yes 437689 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1718, 340322 Corynebacterium glutamicum, Corynebacterium glutamicum R Bacteria UP000031556, UP000006698 500227060, 166228029, 140845365 WP_011897153.1 A4QDR7 THIC_CORGB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3498026 fig|340322.5.peg.1419 586 587 yes 437690 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 912, 323097 Nitrobacter hamburgensis, Nitrobacter hamburgensis X14 Bacteria UP000001953 499830594, 91801289, 122417238 ABE63664.1 WP_011511328.1 Q1QJD3 THIC_NITHX Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1874168 fig|323097.3.peg.2642 633 643 yes 437691 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 388739 Roseobacter sp. SK209-2-6 Bacteria UP000005964 495483421, 126718877 EBA15589.1 WP_008208107.1 fig|388739.3.peg.3165 601 607 yes 437692 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 174, 355277 Leptospira borgpetersenii, Leptospira borgpetersenii serovar Hardjo-bovis JB197 Bacteria UP000000656 499990808, 116123848, 122282075 ABJ75119.1 WP_011671526.1 Q04VF1 THIC_LEPBJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1961099 fig|355277.4.peg.502 511 511 yes 437693 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 156889 Magnetococcus sp. MC-1 Bacteria UP000002586 117610764 ABK46219.1 465 473 yes 437694 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 204773 Herminiimonas arsenicoxydans Bacteria UP000006697 500196700, 166228033, 133737518 WP_011869907.1 A4G224 THIC_HERAR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3824752 fig|204773.3.peg.321 636 637 yes 437695 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 60481 Shewanella sp. MR-7 Bacteria UP000001960 499945515, 113889034 ABI43085.1 WP_011626249.1 fig|60481.10.peg.1979 674 720 yes 437696 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 1444202, 1444228, 1446761, 1281234, 1281249, 1269009, 1281155, 1281255, 1281252, 1281245, 1281221, 1281184, 1281182, 1281174, 1281167, 1281163, 1281156, 1281121, 1281112, 1281111, 1281104, 1281091, 1281048, 1281036, 1281011, 1281003, 1280979, 1181732, 1169385, 1169328, 1181752, 749530, 749550, 340197, 362663 Escherichia coli, Escherichia coli 2-052-05_S4_C1, Escherichia coli 2-005-03_S4_C2, Escherichia coli O81:NM str. 02-3012, Escherichia coli UMEA 3290-1, Escherichia coli UMEA 3426-1, Escherichia coli A35218R, Escherichia coli KOEGE 10 (25a), Escherichia coli UMEA 3617-1, Escherichia coli UMEA 3585-1, Escherichia coli UMEA 3341-1, Escherichia coli UMEA 3217-1, Escherichia coli UMEA 3113-1, Escherichia coli UMEA 3097-1, Escherichia coli UMEA 3022-1, Escherichia coli KOEGE 70 (185a), Escherichia coli KOEGE 58 (171a), Escherichia coli KOEGE 30 (63a), Escherichia coli HVH 194 (4-2356805), Escherichia coli HVH 185 (4-2876639), Escherichia coli HVH 184 (4-3343286), Escherichia coli HVH 175 (4-3405184), Escherichia coli HVH 158 (4-3224287), Escherichia coli HVH 112 (4-5987253), Escherichia coli HVH 100 (4-2850729), Escherichia coli HVH 70 (4-2963531), Escherichia coli HVH 56 (4-2153033), Escherichia coli HVH 28 (4-0907367), Escherichia coli KTE186, Escherichia coli KTE131, Escherichia coli KTE8, Escherichia coli KTE206, Escherichia coli MS 60-1, Escherichia coli MS 200-1, Escherichia coli F11, Escherichia coli 536 Bacteria UP000036210, UP000027676, UP000024248, UP000023813, UP000017631, UP000017622, UP000017468, UP000016379, UP000016104, UP000015983, UP000016250, UP000016106, UP000016145, UP000016321, UP000016432, UP000016312, UP000016154, UP000016127, UP000015997, UP000016094, UP000016390, UP000016347, UP000016136, UP000016049, UP000016101, UP000016096, UP000016420, UP000016331, UP000014114, UP000010519, UP000010520, UP000010608, UP000003458, UP000004237, UP000005334, UP000009182 485653534, 649999814, 641938293, 611044064, 606983123, 554708153, 554705661, 553724225, 536002211, 535801731, 535796759, 535774307, 535689812, 535523695, 535512825, 535474592, 535437572, 535422083, 535387574, 535255855, 535202032, 535196389, 535175274, 535111544, 534934444, 534895010, 534789431, 534751237, 534646352, 508560234, 431592459, 431250978, 430995113, 324015267, 300306539, 190905435, 110345921, 123147440 KDT24701.1, KDO88197.1, EZJ47876.1, EZA12810.1, ESK13591.1, ESK11122.1, ESE39015.1, ERB01651.1, EQZ34547.1, EQZ29701.1, EQZ07659.1, EQY25096.1, EQW62129.1, EQW51461.1, EQW14512.1, EQV78046.1, EQV62886.1, EQV29350.1, EQT99339.1, EQT46177.1, EQT40628.1, EQT19809.1, EQS57786.1, EQQ83500.1, EQQ44900.1, EQP41880.1, EQP04145.1, EQO02728.1, EOX27476.1, ELI63036.1, ELF45035.1, ELD11421.1, EGB84486.1, EFJ61059.1, EDV65066.1, ABG72158.1 WP_001298657.1 Q0TA71 THIC_ECOL5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1993032, 2458407 fig|1169385.3.peg.4220, fig|1290419.3.peg.2967, fig|360118.4.peg.4797, fig|320373.3.peg.5116, fig|357347.4.peg.5507, fig|362663.8.peg.4237, fig|749550.3.peg.2696, fig|1289589.3.peg.3616, fig|320374.3.peg.528, fig|340197.3.peg.4417, fig|357348.6.peg.4699, fig|1181752.3.peg.4454, fig|1181732.3.peg.2116, fig|1229785.3.peg.5016, fig|749530.3.peg.565, fig|557724.3.peg.817, fig|1169328.3.peg.4432, fig|1247713.3.peg.4421, fig|331109.3.peg.1248 626 631 yes 437697 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 196162 Nocardioides sp. JS614 Bacteria UP000000640 500080821, 119538283 ABL82900.1 WP_011756834.1 fig|196162.12.peg.3685 555 561 yes 437698 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 321332 Synechococcus sp. JA-2-3B'a(2-13) Bacteria UP000001938 499751211, 86556319, 109895196 ABD01276.1 WP_011431945.1 Q2JPK6 THIC_SYNJB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1221600 fig|321332.10.peg.282 452 455 yes 437699 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1502, 451754, 195103, 195102 Clostridium perfringens, Clostridium perfringens B str. ATCC 3626, Clostridium perfringens ATCC 13124, Clostridium perfringens str. 13 Bacteria UP000059070, UP000004342, UP000001823, UP000000818 489552356, 170711937, 110673608, 123148924, 24638272, 18144338 EDT24119.1, ABG82595.1 WP_003456962.1 Q0TTB7, Q8XMK9 THIC_CLOP1, THIC_CLOPE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2166951, 4747043, 4735405, 4733190, 185277 fig|451754.5.peg.1328, fig|195103.10.peg.645, fig|195102.1.peg.742 436 436 yes 437700 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 152480, 339670, 396596 Burkholderia ambifaria, Burkholderia ambifaria AMMD, Burkholderia ambifaria IOP40-10 Bacteria UP000032631, UP000005463 493806415, 773027948, 170132996, 115281147, 122323584 AJY21854.1, EDT01411.1, ABI86664.1 WP_006754218.1 Q0BGQ9 THIC_BURCM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7155946, 6044596, 6066206, 1917151 fig|396596.3.peg.5163, fig|339670.3.peg.1819 642 643 yes 437701 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 289380 Clostridium perfringens SM101 Bacteria UP000001824 110684118, 123341945 ABG87488.1 Q0SV55 THIC_CLOPS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 4743571, 1801415 fig|289380.14.peg.644 436 436 yes 437702 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 217511, 314231 Fulvimarina pelagi, Fulvimarina pelagi HTCC2506 Bacteria UP000004310 494126451, 114539131 EAU42251.1 WP_007066226.1 fig|314231.3.peg.2319 599 607 yes 437703 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 110539, 350058 Mycobacterium vanbaalenii, Mycobacterium vanbaalenii PYR-1 Bacteria UP000009159 500101993, 119954558 ABM11563.1 WP_011778000.1 fig|350058.5.peg.712 505 516 yes 437704 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1085, 269796, 1036743 Rhodospirillum rubrum, Rhodospirillum rubrum ATCC 11170, Rhodospirillum rubrum F11 Bacteria UP000001929, UP000001277 499709027, 83593343, 346718515, 83576257, 109895189 AEO48530.1, ABC22808.1 WP_011389761.1, YP_427095.1 Q2RST7 THIC_RHORT Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1144494 fig|269796.9.peg.2092, fig|1036743.4.peg.2058, fig|1085.1.peg.2583 602 621 yes 437705 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1515, 1138384, 1094188, 637887, 492476, 572545, 203119, 1349417 Clostridium thermocellum, Clostridium thermocellum AD2, Clostridium thermocellum YS, Clostridium thermocellum DSM 1313, Clostridium thermocellum JW20, Clostridium thermocellum DSM 2360, Clostridium thermocellum ATCC 27405, Clostridium thermocellum BC1 Bacteria UP000004462, UP000003578, UP000008083, UP000005300, UP000004132, UP000002145, UP000017240 489612063, 380780777, 380771706, 316940654, 281408714, 255992043, 125713345, 551235128 EIC10440.1, EIC05571.1, ADU74688.1, EFB38972.1, EEU02139.1, ABN51837.1 WP_003516504.1 fig|637887.3.peg.1762, fig|572545.3.peg.901, fig|1138384.3.peg.1956, fig|203119.1.peg.2458, fig|1094188.3.peg.882, fig|492476.4.peg.1413 432 432 yes 437706 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 287, 1418240, 1418238, 1418244, 1447531, 1441931, 1402535, 1402536, 1402538, 1408193, 1402494, 1402562, 1402497, 1402500, 1402527, 1402545, 1402557, 652611, 1163396, 1163394, 208963 Pseudomonas aeruginosa, Pseudomonas aeruginosa BWH054, Pseudomonas aeruginosa BWH052, Pseudomonas aeruginosa BWH058, Pseudomonas aeruginosa 3576, Pseudomonas aeruginosa VRFPA09, Pseudomonas aeruginosa BWHPSA043, Pseudomonas aeruginosa BWHPSA044, Pseudomonas aeruginosa BWHPSA046, Pseudomonas aeruginosa VRFPA05, Pseudomonas aeruginosa S54485, Pseudomonas aeruginosa BL21, Pseudomonas aeruginosa 19660, Pseudomonas aeruginosa X13273, Pseudomonas aeruginosa BWHPSA027, Pseudomonas aeruginosa BL04, Pseudomonas aeruginosa BL16, Pseudomonas aeruginosa PA14, Pseudomonas aeruginosa CI27, Pseudomonas aeruginosa ATCC 700888, Pseudomonas aeruginosa UCBPP-PA14 Bacteria UP000065817, UP000024178, UP000023938, UP000024116, UP000024168, UP000022811, UP000023013, UP000020803, UP000021765, UP000017835, UP000017574, UP000017306, UP000017566, UP000017481, UP000017354, UP000017518, UP000017589, UP000014183, UP000005834, UP000006083, UP000000653 489227235, 725659323, 611921281, 611920491, 611884727, 611845139, 582071676, 574048438, 574037019, 574022335, 557559887, 552700302, 552597112, 552475154, 552460952, 552323284, 552316562, 552268034, 508129926, 404529872, 404522381, 115588342, 761595985, 122256865 KHE36702.1, EZO97329.1, EZO96540.1, EZO60930.1, EZO21597.1, EVT88090.1, ETV25068.1, ETV13703.1, ETU99078.1, ESR69741.1, ERZ13772.1, ERY13736.1, ERX32525.1, ERX18620.1, ERV80641.1, ERV76177.1, ERV28240.1, EOT06822.1, EKA39892.1, EKA32890.1, ABJ14357.1 WP_003135615.1 Q02F45 THIC_PSEAB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2199857 fig|1163394.3.peg.5573, fig|208963.12.peg.5391, fig|1163396.3.peg.5630, fig|652611.13.peg.5740 627 627 yes 437707 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 119484, 335543 Syntrophobacter fumaroxidans, Syntrophobacter fumaroxidans MPOB Bacteria UP000001784 500018903, 116699266 ABK18454.1 WP_011699621.1 fig|335543.6.peg.2859 429 429 yes 437708 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 369723 Salinispora tropica CNB-440 Bacteria UP000000235 145305731 ABP56313.1 fig|1169198.3.peg.1411, fig|369723.3.peg.3828 530 530 yes 437709 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 208964, 1367494, 1367493, 1352354, 1352355, 286, 1123015, 287, 1410038, 1410037, 1581118, 1534978, 1400868, 1441462, 1441459, 1009714, 1339263, 1339266, 1418235, 1418236, 1418237, 1418239, 1418241, 1418242, 1418243, 1418245, 1447528, 1418247, 1418246, 1418248, 1447533, 1447532, 1447534, 1447536, 1447535, 1447537, 1447538, 1447539, 1447540, 1447543, 1447544, 1437873, 1081927, 1408275, 1408274, 1408273, 1408271, 1408277, 1408276, 1443105, 1448140, 1402530, 1402532, 1402537, 1402581, 1402540, 1402582, 1427342, 1408272, 1431713, 1434267, 1415629, 1411701, 1411700, 983919, 1402569, 1402487, 1402490, 1402495, 1402508, 1402509, 1402510, 1402515, 1402516, 1402542, 1402543, 1402544, 1402554, 1402561, 1402564, 1402563, 1402566, 1402570, 1163395, 1402486, 1402492, 1402489, 1402493, 1402498, 1402496, 1402501, 1402504, 1402505, 1402506, 1402511, 1402512, 1402513, 1402514, 1402518, 1402520, 1402523, 1402521, 1402522, 1402524, 1402525, 1402526, 1402528, 1402548, 1402550, 1402549, 1402551, 1402556, 1402555, 1402560, 1402558, 1402567, 1402568, 1402572, 1402573, 1402574, 1402575, 1402576, 983918, 1333855, 1340851, 1331059, 1295076, 1125697, 1285581, 1163393, 1163392, 1191475, 1163397, 1093787, 1134459, 1131758, 1131757, 665948, 798130, 350703, 350704, 1341644, 1341645, 1306165, 1286151, 1089456, 557722 Pseudomonas aeruginosa PAO1, Pseudomonas aeruginosa PAO1-VE13, Pseudomonas aeruginosa PAO1-VE2, Pseudomonas aeruginosa PAO581, Pseudomonas aeruginosa c7447m, Pseudomonas aeruginosa DSM 50071, Pseudomonas aeruginosa, Pseudomonas aeruginosa MRSN 321, Pseudomonas aeruginosa MRSN 317, Pseudomonas sp. HMSC05H02, Pseudomonas sp. YS-1p, Pseudomonas aeruginosa VRFPA04, Pseudomonas aeruginosa C2159M, Pseudomonas aeruginosa C2773C, Pseudomonas aeruginosa PAK, Pseudomonas aeruginosa 148, Pseudomonas aeruginosa M10, Pseudomonas aeruginosa BWH049, Pseudomonas aeruginosa BWH050, Pseudomonas aeruginosa BWH051, Pseudomonas aeruginosa BWH053, Pseudomonas aeruginosa BWH055, Pseudomonas aeruginosa BWH056, Pseudomonas aeruginosa BWH057, Pseudomonas aeruginosa BWH059, Pseudomonas aeruginosa 3573, Pseudomonas aeruginosa PS75, Pseudomonas aeruginosa BWH060, Pseudomonas aeruginosa PAO1-GFP, Pseudomonas aeruginosa 3578, Pseudomonas aeruginosa 3577, Pseudomonas aeruginosa 3579, Pseudomonas aeruginosa 3581, Pseudomonas aeruginosa 3580, Pseudomonas aeruginosa BWH029, Pseudomonas aeruginosa BWH030, Pseudomonas aeruginosa BWH031, Pseudomonas aeruginosa BWH032, Pseudomonas aeruginosa BWH035, Pseudomonas aeruginosa BWH036, Pseudomonas aeruginosa PA99, Pseudomonas aeruginosa PA103, Pseudomonas aeruginosa LESlike4, Pseudomonas aeruginosa LESlike1, Pseudomonas aeruginosa LESB65, Pseudomonas aeruginosa LES400, Pseudomonas aeruginosa LESlike7, Pseudomonas aeruginosa LESlike5, Pseudomonas aeruginosa SG17M, Pseudomonas aeruginosa YL84, Pseudomonas aeruginosa BWHPSA038, Pseudomonas aeruginosa BWHPSA040, Pseudomonas aeruginosa BWHPSA045, Pseudomonas aeruginosa PS42, Pseudomonas aeruginosa BWHPSA048, Pseudomonas aeruginosa PS50, Pseudomonas aeruginosa SCV20265, Pseudomonas aeruginosa LES431, Pseudomonas aeruginosa VRFPA07, Pseudomonas aeruginosa VRFPA08, Pseudomonas aeruginosa MTB-1, Pseudomonas aeruginosa DHS29, Pseudomonas aeruginosa DHS01, Pseudomonas aeruginosa 152504, Pseudomonas aeruginosa M8A.3, Pseudomonas aeruginosa MSH10, Pseudomonas aeruginosa CF27, Pseudomonas aeruginosa JJ692, Pseudomonas aeruginosa BWHPSA008, Pseudomonas aeruginosa BWHPSA009, Pseudomonas aeruginosa BWHPSA010, Pseudomonas aeruginosa BWHPSA015, Pseudomonas aeruginosa BWHPSA016, Pseudomonas aeruginosa BL01, Pseudomonas aeruginosa BL02, Pseudomonas aeruginosa BL03, Pseudomonas aeruginosa BL13, Pseudomonas aeruginosa BL20, Pseudomonas aeruginosa BL23, Pseudomonas aeruginosa BL22, Pseudomonas aeruginosa BL25, Pseudomonas aeruginosa M8A.4, Pseudomonas aeruginosa E2, Pseudomonas aeruginosa MSH3, Pseudomonas aeruginosa X24509, Pseudomonas aeruginosa CF18, Pseudomonas aeruginosa UDL, Pseudomonas aeruginosa 6077, Pseudomonas aeruginosa U2504, Pseudomonas aeruginosa BWHPSA001, Pseudomonas aeruginosa BWHPSA004, Pseudomonas aeruginosa BWHPSA005, Pseudomonas aeruginosa BWHPSA006, Pseudomonas aeruginosa BWHPSA011, Pseudomonas aeruginosa BWHPSA012, Pseudomonas aeruginosa BWHPSA013, Pseudomonas aeruginosa BWHPSA014, Pseudomonas aeruginosa BWHPSA018, Pseudomonas aeruginosa BWHPSA020, Pseudomonas aeruginosa BWHPSA023, Pseudomonas aeruginosa BWHPSA021, Pseudomonas aeruginosa BWHPSA022, Pseudomonas aeruginosa BWHPSA024, Pseudomonas aeruginosa BWHPSA025, Pseudomonas aeruginosa BWHPSA026, Pseudomonas aeruginosa BWHPSA028, Pseudomonas aeruginosa BL07, Pseudomonas aeruginosa BL09, Pseudomonas aeruginosa BL08, Pseudomonas aeruginosa BL10, Pseudomonas aeruginosa BL15, Pseudomonas aeruginosa BL14, Pseudomonas aeruginosa BL19, Pseudomonas aeruginosa BL17, Pseudomonas aeruginosa M8A.1, Pseudomonas aeruginosa M8A.2, Pseudomonas aeruginosa C20, Pseudomonas aeruginosa C23, Pseudomonas aeruginosa C40, Pseudomonas aeruginosa C41, Pseudomonas aeruginosa C48, Pseudomonas aeruginosa 138244, Pseudomonas aeruginosa WC55, Pseudomonas aeruginosa RP73, Pseudomonas aeruginosa MSH-10, Pseudomonas aeruginosa PA45, Pseudomonas aeruginosa str. Stone 130, Pseudomonas aeruginosa PA21_ST175, Pseudomonas aeruginosa ATCC 25324, Pseudomonas aeruginosa ATCC 14886, Pseudomonas aeruginosa PAO579, Pseudomonas aeruginosa CIG1, Pseudomonas aeruginosa DK2, Pseudomonas aeruginosa PADK2_CF510, Pseudomonas aeruginosa MPAO1/P2, Pseudomonas aeruginosa MPAO1/P1, Pseudomonas sp. 2_1_26, Pseudomonas aeruginosa 39016, Pseudomonas aeruginosa 2192, Pseudomonas aeruginosa C3719, Pseudomonas aeruginosa WS136, Pseudomonas aeruginosa WS394, Pseudomonas aeruginosa MH27, Pseudomonas aeruginosa 18A, Pseudomonas aeruginosa NCGM2.S1, Pseudomonas aeruginosa LESB58 Bacteria UP000002438 UP000002438, UP000017300, UP000017401, UP000016715, UP000016745, UP000036155, UP000065817, UP000034640, UP000034776, UP000032519, UP000029528, UP000016847, UP000027783, UP000027903, UP000014100, UP000024540, UP000024924, UP000023841, UP000023958, UP000024322, UP000024327, UP000024258, UP000024325, UP000024214, UP000023933, UP000023920, UP000023870, UP000024220, UP000024265, UP000024073, UP000023936, UP000024175, UP000023895, UP000024260, UP000023821, UP000024218, UP000024052, UP000024129, UP000024311, UP000023953, UP000021536, UP000021873, UP000019432, UP000019449, UP000019429, UP000019424, UP000019445, UP000019446, UP000022973, UP000019228, UP000022941, UP000021392, UP000024127, UP000023178, UP000022396, UP000022359, UP000018695, UP000018765, UP000018764, UP000018761, UP000018564, UP000019110, UP000017824, UP000017841, UP000017356, UP000017505, UP000017343, UP000017544, UP000017620, UP000017377, UP000017349, UP000017539, UP000017439, UP000017389, UP000017511, UP000017463, UP000017293, UP000017531, UP000017528, UP000017619, UP000017546, UP000017390, UP000017424, UP000017322, UP000017483, UP000017350, UP000017591, UP000017494, UP000017497, UP000017611, UP000017570, UP000017260, UP000017265, UP000017625, UP000017412, UP000017316, UP000017338, UP000017577, UP000017596, UP000017542, UP000017555, UP000017532, UP000017289, UP000017353, UP000017477, UP000017361, UP000017600, UP000017633, UP000017597, UP000017601, UP000017549, UP000017588, UP000017425, UP000017369, UP000017587, UP000017462, UP000017311, UP000017585, UP000017493, UP000017623, UP000017380, UP000014972, UP000016131, UP000014631, UP000014344, UP000012196, UP000017043, UP000011736, UP000005832, UP000005833, UP000006076, UP000006404, UP000002890, UP000004337, UP000004569, UP000005565, UP000005606, UP000004883, UP000005734, UP000005742, UP000031517, UP000030260, UP000018200, UP000011706, UP000009278, UP000001527 15600166, 651879575, 651873712, 651862644, 651856094, 489186279, 861675875, 856785575, 823575830, 817629916, 816101038, 816093902, 768690747, 763859596, 745840424, 725810124, 725805661, 687285873, 660533112, 658112552, 656997498, 653198671, 653189976, 647087114, 619447601, 618790161, 618779717, 611946018, 611942377, 611933093, 611916831, 611904151, 611903769, 611893849, 611889522, 611880501, 611868458, 611867700, 611858631, 611837047, 611832406, 611828620, 611819101, 611817047, 611804943, 611801446, 611798133, 611786420, 611781283, 611774584, 602739597, 602739458, 589343412, 589337454, 589331530, 589325564, 589319567, 589313688, 584585110, 576904140, 574072782, 574057557, 574029812, 574010325, 574006334, 573995383, 567368795, 566566476, 564841822, 564840186, 563414243, 563274791, 557587011, 557215446, 553899987, 553891213, 552732811, 552720580, 552710100, 552694427, 552678927, 552677686, 552673619, 552664073, 552657650, 552647662, 552646405, 552645888, 552607417, 552605910, 552594002, 552593418, 552574557, 552566270, 552516392, 552504989, 552497660, 552491897, 552486653, 552476087, 552475657, 552444574, 552432338, 552421026, 552418753, 552412982, 552402394, 552400342, 552384754, 552384093, 552383539, 552356353, 552355419, 552352930, 552341614, 552339149, 552332035, 552324537, 552305804, 552298426, 552294154, 552278570, 552269167, 552267274, 552247622, 552247194, 552238800, 552231457, 552215021, 552211818, 552201196, 552198069, 552193348, 543882479, 543876172, 537448911, 533229372, 514250068, 508132366, 508130749, 477557327, 476644135, 453046483, 404540968, 404528329, 404518928, 404345456, 403245085, 392322154, 384401858, 375049344, 375043291, 354830088, 310882407, 126197517, 126170244, 9951256, 831197181, 777188251, 747643509, 727033252, 698156938, 685842943, 670356977, 560111407, 451759707, 348032076, 226695853, 218774296, 24638284 AKO89159.1, KMN03850.1, KLI81782.1, AKG02144.1, KKJ48417.1, KKJ41331.1, KJJ20181.1, KJC19086.1, AJD60668.1, KHE64305.1, KHE59903.1, KGD91128.1, AID82432.1, KEI27267.1, KEF94123.1, KEA19752.1, KEA11119.1, KDR46685.1, KAJ89924.1, KAJ26467.1, KAJ16501.1, EZP21968.1, EZP18339.1, EZP09081.1, EZO92890.1, EZO80279.1, EZO79898.1, EZO70020.1, EZO65721.1, EZO56732.1, EZO44725.1, EZO43969.1, EZO34946.1, EZO13640.1, EZO09065.1, EZO05321.1, EZN95975.1, EZN93933.1, EZN81966.1, EZN78546.1, EZN75249.1, EZN63639.1, EZN58597.1, EZN51950.1, EYU00409.1, EYU00278.1, AHL15949.1, AHL09992.1, AHL04069.1, AHK98103.1, AHK92107.1, AHK86229.1, EWH24456.1, AHH48630.1, ETV49305.1, ETV34165.1, ETV06533.1, ETU87126.1, ETU83161.1, ETU72264.1, AHC79740.1, AHC67997.1, ETD53272.1, ETD51724.1, AHB58665.1, ESZ79620.1, ESR94722.1, ESQ63317.1, AGY73519.1, AGY67907.1, ERZ46022.1, ERZ33984.1, ERZ23540.1, ERZ07929.1, ERY92517.1, ERY91286.1, ERY87228.1, ERY77765.1, ERY72100.1, ERY62144.1, ERY60892.1, ERY60376.1, ERY23988.1, ERY22489.1, ERY10639.1, ERY10057.1, ERX91300.1, ERX83117.1, ERX73282.1, ERX61977.1, ERX54751.1, ERX49025.1, ERX43881.1, ERX33454.1, ERX33025.1, ERX02850.1, ERW90342.1, ERW79167.1, ERW76945.1, ERW71292.1, ERW60831.1, ERW58795.1, ERW43334.1, ERW42676.1, ERW42140.1, ERW15248.1, ERW14319.1, ERW11857.1, ERW00400.1, ERV98228.1, ERV91273.1, ERV83996.1, ERV65519.1, ERV58254.1, ERV53998.1, ERV38644.1, ERV30896.1, ERV27481.1, ERV08125.1, ERV07698.1, ERU98866.1, ERU91599.1, ERU75501.1, ERU72306.1, ERU61899.1, ERU58845.1, ERU54198.1, AGV60480.1, AGV65331.1, ERF06421.1, EQM84057.1, AGO42449.1, EOT09254.1, EOT07639.1, ENH90828.1, EMZ50530.1, EME94199.1, EKA50348.1, EKA38431.1, EKA29722.1, EJZ71808.1, EJY58916.1, AFM67534.1, EIE48211.1, EHS41844.1, EHS35920.1, EHF14147.1, EFQ41001.1, EAZ61580.1, EAZ55755.1, AAG08358.1 NP_253660.1, YP_008709169.1, YP_008696888.1, YP_008560748.1, YP_008555247.1, WP_003095696.1 B7V362, Q9HUJ2 THIC_PSEA8, THIC_PSEAE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2940704, 2547426, 5822339, 2541349, 61420 fig|1163395.3.peg.5176, fig|1134459.3.peg.437, fig|1009714.6.peg.5515, fig|350704.7.peg.5805, fig|1286151.3.peg.6, fig|1089456.3.peg.549, fig|1131757.3.peg.3333, fig|1285581.3.peg.1892, fig|557722.3.peg.5485, fig|798130.4.peg.3894, fig|1163397.3.peg.5426, fig|983919.3.peg.3148, fig|1163392.3.peg.5508, fig|350703.3.peg.3384, fig|388272.4.peg.5383, fig|1000561.3.peg.115, fig|1163393.3.peg.5887, fig|1191475.3.peg.5032, fig|1169413.3.peg.3004, fig|1131758.3.peg.2877, fig|1093787.3.peg.5333, fig|1214916.3.peg.5161, fig|665948.3.peg.2182, fig|1198629.3.peg.182, fig|509633.3.peg.5124, fig|1295076.3.peg.4747, fig|6666666.7915.peg.4770, fig|1331059.3.peg.5211, fig|983918.3.peg.3028, fig|208964.1.peg.4970 627 627 yes 437710 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 43663, 290340 Arthrobacter aurescens, Arthrobacter aurescens TC1 Bacteria UP000000637 500101036, 119951649 ABM10559.1 WP_011777043.1 fig|290340.10.peg.4545 573 578 yes 437711 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1219, 167547, 74546 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9311, Prochlorococcus marinus str. MIT 9312 Bacteria UP000030422, UP000002715 499696512, 691678279, 78713588, 123553675 KGG02248.1, ABB50765.1 WP_011377246.1 Q318D0 THIC_PROM9 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1046886 fig|74546.3.peg.1083 453 456 yes 437712 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 666, 345075 Vibrio cholerae, Vibrio cholerae V51 Bacteria UP000028983, UP000011694 487813967, 669366245, 125621902 KFD94690.1, EAZ50227.1 WP_001887433.1 fig|1233524.3.peg.769, fig|1235442.3.peg.652, fig|1235444.3.peg.1274, fig|1235473.3.peg.217, fig|1235454.3.peg.626, fig|345075.15.peg.1347, fig|1294275.3.peg.1103, fig|1235456.3.peg.1428, fig|1235443.3.peg.362 639 645 yes 437713 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 622, 300267, 1401259, 1401327, 754093 Shigella dysenteriae, Shigella dysenteriae Sd197, Shigella dysenteriae WRSd5, Shigella dysenteriae WRSd3, Shigella dysenteriae 1617 Bacteria UP000002716, UP000018276, UP000017944, UP000031647 447199678, 82778830, 559663387, 559657698, 558575612, 308928321, 81242978, 109895192 ESU84728.1, ESU79927.1, AHA67750.1, EFP73783.1, ABB63688.1 WP_001276934.1, YP_405179.1 Q32AG7 THIC_SHIDS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1157560 fig|216598.1.peg.3293, fig|300267.13.peg.4424, fig|754093.3.peg.434 626 631 yes 437714 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1219, 59922 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9303 Bacteria UP000002274 500148878, 123962196, 166228054 ABM76952.1 WP_011824881.1 A2C642 THIC_PROM3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1218302 fig|59922.7.peg.203 456 459 yes 437715 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 296591 Polaromonas sp. JS666 Bacteria UP000001983 499800280, 91695175, 123356311 ABE42004.1 WP_011481014.1 Q12HI8 THIC_POLSJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 708298, 1819765 fig|296591.1.peg.4942 637 638 yes 437716 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 415426 Hyperthermus butylicus DSM 5456 Archaea UP000002593 123977880 ABM80161.1 A2BJK0 A2BJK0_HYPBU fig|415426.7.peg.315 431 431 yes 437717 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1804, 350054 Mycobacterium gilvum, Mycobacterium gilvum PYR-GCK Bacteria UP000000232 500221553, 145213835 ABP43239.1 WP_011891660.1 fig|278137.3.peg.308, fig|350054.11.peg.769 527 528 yes 437718 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 111527, 243160, 13373, 28450, 1439861, 1437001, 1434210, 1434208, 1434204, 1434202, 1434930, 1435365, 320389, 436115, 320390, 412021, 370895, 334803, 334802, 412022, 320388 Burkholderia mallei ATCC 23344, Burkholderia mallei, Burkholderia pseudomallei, Burkholderia pseudomallei TSV5, Burkholderia pseudomallei MSHR1000, Burkholderia pseudomallei TSV 25, Burkholderia pseudomallei ABCPW 30, Burkholderia pseudomallei TSV 31, Burkholderia pseudomallei TSV 43, Burkholderia pseudomallei MSHR7334, Burkholderia pseudomallei TSV 48, Burkholderia mallei NCTC 10247, Burkholderia mallei PRL-20, Burkholderia mallei GB8 horse 4, Burkholderia mallei ATCC 10399, Burkholderia mallei 2002721280, Burkholderia mallei JHU, Burkholderia mallei FMH, Burkholderia mallei NCTC 10229, Burkholderia mallei SAVP1 Bacteria UP000006693, UP000032647, UP000029571, UP000030586, UP000030483, UP000030402, UP000030590, UP000030409, UP000030423, UP000030388, UP000030086, UP000002284, UP000003556, UP000003995, UP000006012, UP000002773, UP000003975, UP000002802, UP000002283, UP000006708 490298524, 53724060, 816664388, 773056450, 773042199, 773008467, 772995864, 772984137, 772909826, 761377057, 760211982, 760201145, 715010020, 714614257, 714579420, 714558678, 714504414, 714466980, 705731639, 701286126, 693272256, 686914630, 686877902, 686836648, 685796795, 685694570, 685676067, 685672389, 685665057, 243061880, 238524760, 160699761, 148028038, 147752538, 147747558, 126243322, 124291778, 121227943, 52427483, 166228020, 166228019, 166228018, 81603891 KKM56378.1, AJY35702.1, AJX63767.1, AJX52403.1, AJX47773.1, AJX42720.1, AJX02454.1, KIY08511.1, KIX58412.1, KIX47850.1, KGX51596.1, KGW44077.1, KGW09797.1, KGV89136.1, KGV35088.1, KGV05463.1, KGS76682.1, AIV48203.1, AIS28234.1, KGC93021.1, KGC56773.1, KGC16109.1, AIP77949.1, AIO81684.1, AIO63188.1, AIO59512.1, AIO52183.1, EES44066.1, EEP88191.1, EDP89731.1, EDK86059.1, EDK59604.1, EDK54634.1, ABO06415.1, ABN01047.1, ABM50461.1, AAU48076.1 WP_004193963.1, YP_104578.1 A3MIG6, A2S3Z6, Q62FE9, A1V2S9 THIC_BURM7, THIC_BURM9, THIC_BURMA, THIC_BURMS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 737828, 1861605, 4348550, 4483783, 2347791, 2112863, 2755604, 1854613, 2418170, 2415067, 2345279 fig|412022.9.peg.2844, fig|370895.4.peg.3318, fig|243160.12.peg.3167, fig|412021.3.peg.4816, fig|320389.6.peg.2767, fig|320390.3.peg.618, fig|436115.3.peg.3703, fig|334803.3.peg.2181, fig|334802.3.peg.4011, fig|320386.3.peg.600, fig|320387.3.peg.2961, fig|320388.3.peg.1757 642 643 yes 437719 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 351160 uncultured methanogenic archaeon RC-I Archaea UP000000663 110620324 Q0W7P1 Q0W7P1_METAR fig|351160.3.peg.2580 417 424 yes 437720 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1827, 745408, 101510 Rhodococcus sp. JVH1, Rhodococcus jostii RHA1 Bacteria UP000009024, UP000008710 497111137, 396932853, 110818705 EJJ00014.1, ABG93989.1 WP_009474848.1 fig|186196.5.peg.4452, fig|101510.15.peg.2203, fig|745408.3.peg.2599 541 548 yes 437721 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 94122 Shewanella sp. ANA-3 Bacteria UP000002589 500036216, 117612713 ABK48167.1 WP_011716934.1 fig|94122.5.peg.2011 674 720 yes 437722 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2198, 368407 Methanoculleus marisnigri, Methanoculleus marisnigri JR1 Archaea UP000054598, UP000002146 500169973, 125862298, 166228042 ABN57487.1 WP_011844398.1 A3CVT7 THIC_METMJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2005951 fig|368407.6.peg.1552 419 424 yes 437723 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 351052, 187272 Alkalilimnicola ehrlichii, Alkalilimnicola ehrlichii MLHE-1 Bacteria UP000001962 499948326, 114226866 ABI56665.1 WP_011629060.1 fig|187272.10.peg.1313 626 630 yes 437724 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 85, 1280951, 228405 Hyphomonas hirschiana VP5, Hyphomonas neptunium ATCC 15444 Bacteria UP000025061, UP000001959 499967588, 630945697, 114739970 KCZ91989.1, ABI78095.1 WP_011648306.1 fig|228405.5.peg.3197 623 630 yes 437725 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1219, 167546 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9301 Bacteria UP000001430 500190408, 126544185, 166228052 ABO18427.1 WP_011863712.1 A3PFA2 THIC_PROM0 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1197703 fig|167546.3.peg.1819 453 456 yes 437726 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 43663, 290340 Arthrobacter aurescens, Arthrobacter aurescens TC1 Bacteria UP000000637 500099117, 119947620 ABM06531.1 WP_011775124.1 fig|290340.10.peg.2489 596 678 yes 437727 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 386487, 413404 Candidatus Ruthia magnifica, Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica) Bacteria UP000002587 500057880, 118567367, 226695854 ABL02172.1 WP_011737797.1 A1AW65 THIC_RUTMC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2120972 fig|413404.11.peg.458 621 622 yes 437728 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 644, 380703 Aeromonas hydrophila, Aeromonas hydrophila subsp. hydrophila ATCC 7966 Bacteria UP000032249, UP000000756 500023695, 117621153, 117562560 ABK39508.1 WP_011704413.1, YP_854968.1 2032226 fig|380703.5.peg.414 645 663 yes 437729 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 119060, 1229514, 381666 Ralstonia sp. GA3-3, Ralstonia eutropha H16 Bacteria UP000013900, UP000008210 498512887, 490336628, 123134517, 113525042 EON17534.1 WP_010813323.1 Q0KF34 THIC_CUPNH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2036591 fig|381666.6.peg.595, fig|1229514.3.peg.4485 624 626 yes 437730 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 129337, 495036, 420246 Geobacillus sp. G11MC16, Geobacillus thermodenitrificans NG80-2 Bacteria UP000003241, UP000001578 496156738, 196210199, 134265533, 166228032 EDY04965.1, ABO65728.1 WP_008881245.1 A4IK74 THIC_GEOTN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6240146, 3693831 fig|495036.3.peg.2878, fig|420246.5.peg.332 563 563 yes 437731 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 32008, 60552, 1449978, 416344, 269482 Burkholderia vietnamiensis, Burkholderia vietnamiensis LMG 10929, Burkholderia sp. KJ006, Burkholderia vietnamiensis G4 Bacteria UP000063064, UP000032641, UP000010108, UP000002287 500213921, 815013980, 773006046, 387576759, 134138400, 166228023 KKI39111.1, AJY07659.1, AFJ85475.1, ABO54143.1 WP_011884090.1 A4JCZ0 THIC_BURVG Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6817728 fig|269482.11.peg.5369, fig|416344.3.peg.1127 642 643 yes 437732 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 290317 Chlorobium phaeobacteroides DSM 266 Bacteria UP000008701 119354996 ABL65867.1 fig|290317.7.peg.1948 565 566 yes 437733 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 985, 269798 Cytophaga hutchinsonii, Cytophaga hutchinsonii ATCC 33406 Bacteria UP000001822 499902914, 110279346 ABG57532.1 WP_011583648.1 fig|269798.12.peg.229 630 630 yes 437734 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 470, 400667 Acinetobacter baumannii, Acinetobacter baumannii ATCC 17978 Bacteria UP000028632, UP000006737 500183795, 126640344 WP_011858118.1, YP_001083328.1 3627594 fig|992404.3.peg.3274, fig|1168590.3.peg.3325, fig|903896.3.peg.1493, fig|557600.3.peg.3160, fig|1221287.3.peg.1517, fig|1094474.3.peg.2883, fig|1094488.3.peg.664, fig|903917.3.peg.3835, fig|1221254.3.peg.3717, fig|903933.3.peg.3317, fig|886886.3.peg.2810, fig|981329.3.peg.1989, fig|1222033.3.peg.1220, fig|903895.3.peg.3590, fig|1217628.3.peg.3227, fig|1221256.3.peg.1087, fig|1221268.3.peg.3081, fig|525243.3.peg.879, fig|1217644.3.peg.3329, fig|1217636.3.peg.277, fig|1217673.3.peg.166, fig|903937.3.peg.837, fig|1221248.3.peg.236, fig|1221288.3.peg.3507, fig|1221271.3.peg.2874, fig|945556.3.peg.419, fig|1222031.3.peg.2179, fig|903914.3.peg.2311, fig|903920.3.peg.3367, fig|1221250.3.peg.81, fig|903925.3.peg.51, fig|1168588.3.peg.3611, fig|1094484.3.peg.838, fig|1216295.3.peg.292, fig|1116236.3.peg.1451, fig|903898.3.peg.580, fig|1221276.3.peg.211, fig|710094.4.peg.1881, fig|525242.3.peg.631, fig|1293574.3.peg.3060, fig|1198108.3.peg.2353, fig|1094479.3.peg.1163, fig|1224747.3.peg.3082, fig|1094480.3.peg.1718, fig|903901.3.peg.3745, fig|903894.3.peg.3009, fig|903904.3.peg.3094, fig|1217646.3.peg.3355, fig|1221246.3.peg.2209, fig|1221277.3.peg.1668, fig|1210907.3.peg.2670, fig|1221266.3.peg.3470, fig|1221275.3.peg.1567, fig|1217630.3.peg.3465, fig|1221259.3.peg.486, fig|696749.3.peg.304, fig|1094477.3.peg.1723, fig|1217641.3.peg.794, fig|557601.3.peg.1361, fig|1217627.3.peg.3405, fig|1279013.3.peg.450, fig|1217640.3.peg.3399, fig|1221292.3.peg.4, fig|992403.3.peg.3051, fig|1221272.3.peg.2528, fig|1217985.3.peg.444, fig|903923.3.peg.2171, fig|400667.4.peg.265, fig|575584.3.peg.1939, fig|1217631.3.peg.3455, fig|903907.3.peg.326, fig|1116234.3.peg.985, fig|903912.3.peg.23, fig|405416.6.peg.373, fig|1221262.3.peg.346, fig|1221249.3.peg.498, fig|1221253.3.peg.23, fig|480119.5.peg.338, fig|1217642.3.peg.2669, fig|1278070.3.peg.520, fig|1221273.3.peg.1110, fig|903911.3.peg.1856, fig|592014.3.peg.1845, fig|1094475.3.peg.133, fig|509173.8.peg.3374, fig|1100841.3.peg.528, fig|1217645.3.peg.273, fig|903926.3.peg.101, fig|886889.3.peg.430, fig|1217635.3.peg.3443, fig|1217632.3.peg.3326, fig|903934.3.peg.34, fig|1221265.3.peg.2338, fig|981224.3.peg.23, fig|903903.3.peg.1192, fig|903924.3.peg.661, fig|903909.3.peg.2080, fig|903889.3.peg.2969, fig|945555.3.peg.3316, fig|889738.3.peg.3693, fig|903899.3.peg.3185, fig|1223564.3.peg.398, fig|1094481.3.peg.1061, fig|903892.3.peg.3047, fig|1094487.3.peg.888, fig|1217638.3.peg.286, fig|1221286.3.peg.3565, fig|981328.3.peg.350, fig|1116233.3.peg.1325, fig|1221290.3.peg.2383, fig|1221245.3.peg.3512, fig|497978.4.peg.304, fig|886888.3.peg.2978, fig|903931.3.peg.1889, fig|1217647.3.peg.2843, fig|1094486.3.peg.1107, fig|1217643.3.peg.3356, fig|1094470.3.peg.2681, fig|903927.3.peg.26, fig|903906.3.peg.1533, fig|1224141.3.peg.326, fig|903935.3.peg.3702, fig|1224166.3.peg.516, fig|1221264.3.peg.3640, fig|1221251.3.peg.618, fig|1222032.3.peg.1613, fig|903908.3.peg.2661, fig|903932.3.peg.542, fig|1094471.3.peg.58, fig|1217637.3.peg.3302, fig|1221267.3.peg.2100, fig|1221270.3.peg.1485, fig|1094483.3.peg.1819, fig|903905.3.peg.79, fig|1094478.3.peg.1319, fig|980514.3.peg.314, fig|903919.3.peg.2436 580 580 yes 437735 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 29292, 272844 Pyrococcus abyssi, Pyrococcus abyssi GE5 Archaea UP000009139 499169500, 380741412, 24638291, 5458085 WP_010867776.1 Q9V0X8 THIC_PYRAB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5245 fig|272844.1.peg.683 429 429 yes 437736 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 630, 393305 Yersinia enterocolitica, Yersinia enterocolitica subsp. enterocolitica 8081 Bacteria UP000029427, UP000000642 500139386, 123440683, 122087644 WP_011815389.1, YP_001004675.1 2075695 fig|630.2.peg.287, fig|393305.7.peg.386 617 628 yes 437737 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2224, 349307 Methanosaeta thermophila, Methanosaeta thermophila PT Archaea UP000000674 500014791, 116753632, 116665083 ABK14110.1 WP_011695509.1, YP_842750.1 A0B5Y6 A0B5Y6_METTP 1934050 fig|349307.9.peg.307 426 426 yes 437738 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 405948 Saccharopolyspora erythraea NRRL 2338 Bacteria UP000006728 133909745 fig|405948.11.peg.520 544 547 yes 437739 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 192073, 318161 Shewanella denitrificans, Shewanella denitrificans OS217 Bacteria UP000001982 499815477, 91715128, 123060967 ABE55054.1 WP_011496211.1 Q12NC2 THIC_SHEDO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6910174 fig|318161.14.peg.1736 660 686 yes 437740 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1542, 1443118, 1443119, 1443120, 1443121, 386415 Clostridium novyi, Clostridium novyi A str. GD211209, Clostridium novyi A str. BKT29909, Clostridium novyi A str. NCTC 538, Clostridium novyi A str. 4540, Clostridium novyi NT Bacteria UP000027939, UP000027624, UP000027961, UP000027790, UP000008220 500041873, 658082363, 658077936, 658074816, 658074274, 118135233, 166987537 KEH95305.1, KEH91062.1, KEH88029.1, KEH87498.1, ABK62277.1 WP_011722591.1 A0Q1U9 THIC_CLONN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2055846 fig|386415.6.peg.1633 437 437 yes 437741 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 332163, 234267 Candidatus Solibacter usitatus, Candidatus Solibacter usitatus Ellin6076 Bacteria UP000000671 500002450, 116223684, 122255258 ABJ82393.1 WP_011683168.1 Q028Z8 THIC_SOLUE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2220054 fig|234267.13.peg.1468 455 461 yes 437742 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 364317, 391735 Verminephrobacter eiseniae, Verminephrobacter eiseniae EF01-2 Bacteria UP000000374 500133285, 121553134 ABM57283.1 WP_011809290.1 fig|391735.5.peg.1436 620 631 yes 437743 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 80869, 397945 Acidovorax citrulli, Acidovorax citrulli AAC00-1 Bacteria UP000002596 500117982, 120587987, 166228007 ABM31427.1 WP_011793987.1 A1TKD9 THIC_ACIAC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2086320 fig|397945.5.peg.720, fig|397945.6.peg.848 614 617 yes 437744 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 364410, 391165 Granulibacter bethesdensis, Granulibacter bethesdensis CGDNIH1 Bacteria UP000001963 499950082, 114314946 ABI61006.1 WP_011630816.1 fig|391165.8.peg.110 603 610 yes 437745 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 64471 Synechococcus sp. CC9311 Bacteria UP000001961 499937381, 113882419, 123031932 ABI47377.1 WP_011618115.1 Q0IDV6 THIC_SYNS3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1362903 fig|64471.10.peg.136 462 465 yes 437746 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1076, 316055 Rhodopseudomonas palustris, Rhodopseudomonas palustris BisA53 Bacteria UP000032515, UP000000654 499982778, 115518029, 122296573 ABJ06013.1 WP_011663496.1 Q07PX1 THIC_RHOP5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1827566 fig|316055.14.peg.2052 630 641 yes 437747 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1772, 246196 Mycobacterium smegmatis, Mycobacterium smegmatis str. MC2 155 Bacteria UP000029911, UP000029906 500046504, 118467543, 118168830 ABK69726.1 WP_011727222.1, YP_885230.1 1745407 fig|246196.1.peg.818 523 524 yes 437748 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1809, 362242 Mycobacterium ulcerans, Mycobacterium ulcerans Agy99 Bacteria UP000000765 500061429, 118618879, 118570989, 166228048 ABL05740.1 WP_011741346.1, YP_907211.1 A0PTS1 THIC_MYCUA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1987390 fig|362242.7.peg.4195 544 546 yes 437749 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 87882, 292, 350701, 1385930 Burkholderia cepacia, Burkholderia dolosa AUO158, Burkholderia dolosa PC543 Bacteria UP000063625, UP000053482, UP000032883 493817122, 808742852, 773017231, 571039603, 124895360 AKE04094.1, AJY12320.1, ETP65894.1, EAY69240.1 WP_006764698.1 fig|350701.3.peg.2194 642 643 yes 437750 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 863, 335541 Syntrophomonas wolfei, Syntrophomonas wolfei subsp. wolfei str. Goettingen Bacteria UP000001968 499959341, 114337122, 122318719 ABI67970.1 WP_011640075.1 Q0AZ84 THIC_SYNWW Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1902744 fig|335541.4.peg.611 424 424 yes 437751 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 351348 Marinobacter aquaeolei VT8 Bacteria UP000000998 120323585 ABM17900.1 fig|351348.5.peg.1136 624 654 yes 437752 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 349124 Halorhodospira halophila SL1 Bacteria UP000000647 121589463 ABM62043.1 fig|349124.5.peg.1248 521 536 yes 437753 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 338966 Pelobacter propionicus DSM 2379 Bacteria UP000006732 118502178 ABK98660.1 fig|338966.9.peg.1192, fig|338966.5.peg.1121 591 592 yes 437754 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 44001, 351627 Caldicellulosiruptor saccharolyticus, Caldicellulosiruptor saccharolyticus DSM 8903 Bacteria UP000000256 500264984, 145408898 ABP65902.1 WP_011915868.1 fig|351627.4.peg.237 420 421 yes 437755 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 313612 Lyngbya sp. PCC 8106 Bacteria UP000000737 497470190, 119456014 EAW37148.1 WP_009784388.1 fig|313612.3.peg.2328 459 460 yes 437756 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 174, 1303729, 355276 Leptospira borgpetersenii, Leptospira borgpetersenii serovar Hardjo-bovis str. Sponselee, Leptospira borgpetersenii serovar Hardjo-bovis L550 Bacteria UP000011873, UP000000655 499990246, 463319140, 116121979, 122282984 EMJ85096.1, ABJ80022.1 WP_011670964.1 Q04Y23 THIC_LEPBL Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1960177 fig|1291206.3.peg.2219, fig|1218567.3.peg.93, fig|355276.3.peg.3458 511 511 yes 437757 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 46770, 414004 Cenarchaeum symbiosum, Cenarchaeum symbiosum A Archaea UP000000758 503246826, 118193941 ABK76859.1 WP_013481487.1 A0RU42 A0RU42_CENSY 450 451 yes 437758 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 314344, 314345 Mariprofundus ferrooxydans, Mariprofundus ferrooxydans PV-1 Bacteria UP000037016, UP000005297 497537482, 114552599 EAU55059.1 WP_009851680.1 622 622 yes 437759 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 39152, 402880 Methanococcus maripaludis, Methanococcus maripaludis C5 Archaea UP000000253 500196029, 132664140, 166228040 ABO35786.1 WP_011869236.1 A4G002 THIC_METM5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3638065 fig|402880.8.peg.1469 426 426 yes 437760 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 431944 Magnetospirillum gryphiswaldense MSR-1 Bacteria 144900911 fig|431944.4.peg.127 600 605 yes 437761 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 645, 1076135, 382245 Aeromonas salmonicida, Aeromonas salmonicida subsp. salmonicida 01-B526, Aeromonas salmonicida subsp. salmonicida A449 Bacteria UP000052231, UP000006428, UP000000225 491458507, 356687349, 142853537 EHI51931.1, ABO91858.1 WP_005316285.1 fig|382245.13.peg.3869, fig|1076135.3.peg.2562 644 668 yes 437762 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 198214, 623, 1435046, 1282358, 1282357, 766151, 766158, 1086030, 754092, 766149, 766152, 766159, 766157, 198215, 591020, 373384 Shigella flexneri 2a str. 301, Shigella flexneri, Shigella flexneri G1663, Shigella flexneri Shi06HN006, Shigella flexneri 2003036, Shigella flexneri K-404, Shigella flexneri 2850-71, Shigella flexneri 5a str. M90T, Shigella flexneri J1713, Shigella flexneri K-304, Shigella flexneri K-671, Shigella flexneri 2930-71, Shigella flexneri 2747-71, Shigella flexneri 2a str. 2457T, Shigella flexneri 2002017, Shigella flexneri 5 str. 8401 Bacteria UP000029282, UP000035418, UP000028935, UP000028957, UP000005996, UP000004845, UP000005108, UP000004887, UP000003848, UP000002982, UP000003662, UP000005852, UP000032709, UP000001884, UP000000659 24115278, 447199664, 828443982, 721536399, 675100896, 675094466, 391276082, 391245407, 383469268, 335573710, 333014352, 332765564, 332762839, 332749190, 313648644, 281603379, 110617392, 30042984, 24054572, 713638568, 123047721, 47606156 AKK56464.1, KGY79755.1, AIL43368.1, AIL38434.1, EIQ34861.1, EIQ04676.1, EID64289.1, EGM60052.1, EGK33705.1, EGJ95778.1, EGJ93098.1, EGJ79612.1, EFS13084.1, ADA76363.1, ABF06059.1, AAP18706.1, AAN45495.1 NP_709788.1, WP_001276920.1 Q0SY06, Q83PB8 THIC_SHIF8, THIC_SHIFL Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 365834, 289102, 2022647 fig|198215.1.peg.3153, fig|373384.10.peg.4568, fig|1086030.3.peg.4389, fig|766151.3.peg.22, fig|766158.3.peg.4008, fig|198214.1.peg.3828, fig|766159.3.peg.4986, fig|766157.3.peg.5117, fig|591020.3.peg.4752, fig|754092.3.peg.3753, fig|766149.3.peg.4108, fig|766152.3.peg.15 626 631 yes 437763 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 666, 1095649, 412966 Vibrio cholerae, Vibrio cholerae O1 str. EM-1676A, Vibrio cholerae 1587 Bacteria UP000028983, UP000012156, UP000004523 445993258, 469744760, 124115237 EMQ57373.1, EAY34057.1 WP_000071113.1 fig|1095649.3.peg.837, fig|412966.10.peg.1981 639 645 yes 437764 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 29543, 338966 Pelobacter propionicus, Pelobacter propionicus DSM 2379 Bacteria UP000006732 500056537, 118503718 ABL00201.1 WP_011736454.1 fig|338966.5.peg.2569 432 432 yes 437765 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 39960, 314225 Erythrobacter litoralis, Erythrobacter litoralis HTCC2594 Bacteria UP000027866, UP000008808 499734146, 84787870, 122543911 ABC64052.1 WP_011414880.1 Q2N8D9 THIC_ERYLH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1232545 fig|314225.3.peg.1078 622 629 yes 437766 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 56812, 318167 Shewanella frigidimarina, Shewanella frigidimarina NCIMB 400 Bacteria UP000055702, UP000000684 499956923, 114334665 ABI72047.1 WP_011637657.1 fig|318167.10.peg.2130 651 666 yes 437767 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 347, 1458476, 360094, 291331, 342109 Xanthomonas oryzae, Xanthomonas oryzae pv. oryzae PXO86, Xanthomonas oryzae pv. oryzae PXO99A, Xanthomonas oryzae pv. oryzae KACC10331, Xanthomonas oryzae pv. oryzae MAFF 311018 Bacteria UP000037499, UP000032321, UP000001740, UP000006735, UP000001957 499726959, 765203308, 188522940, 238689533, 109895205, 109895204, 84366464 AJQ84606.1, ACD60885.1 WP_011407693.1 Q2P755, B2SNG3, Q5H4C0 THIC_XANOM, THIC_XANOP, THIC_XANOR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3990706, 1923491, 5516284, 953037 fig|360094.3.peg.4383, fig|291331.3.peg.947, fig|342109.7.peg.967, fig|360094.4.peg.4464 624 625 yes 437768 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1175445, 351160 Methanocella arvoryzae, uncultured methanogenic archaeon RC-I Archaea UP000000663 500970158, 110622514 WP_012034796.1 Q0W1F1 Q0W1F1_METAR fig|351160.3.peg.485 419 424 yes 437769 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 105560, 420662 Methylibium petroleiphilum, Methylibium petroleiphilum PM1 Bacteria UP000000366 500153206, 124259578, 166228043 ABM94572.1 WP_011829209.1 A2SG83 THIC_METPP Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2130335 fig|420662.8.peg.1519 623 628 yes 437770 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 60478, 326297 Shewanella amazonensis, Shewanella amazonensis SB2B Bacteria UP000009175 500083960, 119767495, 166228060 ABM00066.1 WP_011759973.1 A1S6Q9 THIC_SHEAM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6937718 fig|326297.7.peg.1750 652 664 yes 437771 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 351745 Shewanella sp. W3-18-1 Bacteria UP000002597 500113380, 120558987 ABM24914.1 WP_011789385.1 fig|351745.7.peg.1950 655 706 yes 437772 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1218, 146891 Prochlorococcus marinus str. AS9601 Bacteria UP000002590 500143220, 123199463, 166228056 ABM71104.1 WP_011819223.1 A2BTJ3 THIC_PROMS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1211136 fig|146891.7.peg.1841 453 456 yes 437773 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1076, 316057 Rhodopseudomonas palustris, Rhodopseudomonas palustris BisB5 Bacteria UP000032515, UP000001818 499823089, 91684354, 123762574 ABE40656.1 WP_011503823.1 Q133T3 THIC_RHOPS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1833808 fig|316057.3.peg.2865 630 641 yes 437774 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 221359 Synechococcus sp. RS9916 Bacteria UP000004972 116069720 EAU75472.1 480 484 yes 437775 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1496, 272563, 1232197, 1151427, 1151432, 1151431, 1151419, 1151324, 1151415, 1151417, 1151276, 1151277, 1151284, 1151413, 1151412, 1151282, 1151279, 1151283, 1151278, 1232196, 1232195, 1232192, 1232194, 1232193, 1151440, 1151439, 1151438, 1151437, 1151436, 1151435, 1151434, 1151433, 1151430, 1151429, 1151426, 1151424, 1151425, 1151423, 1151422, 1151421, 1151418, 1151416, 1151420, 1151414, 1151408, 1151409, 1151407, 1151405, 1151406, 1151404, 1151403, 1151400, 1151401, 1151402, 1151399, 1151398, 1151396, 1151395, 1151394, 1151391, 1151392, 1151393, 1151390, 1151388, 1151386, 1151387, 1151384, 1151385, 1151383, 1151380, 1151379, 1151378, 1151377, 1151376, 1151375, 1151374, 1151367, 1151373, 1151368, 1151372, 1151366, 1151364, 1151362, 1151363, 1151361, 1151359, 1151355, 1151360, 1151357, 1151353, 1151354, 1151349, 1151352, 1151351, 1151350, 1151348, 1151346, 1151347, 1151345, 1151344, 1151341, 1151343, 1151342, 1151338, 1151340, 1151339, 1151336, 1151337, 1151335, 1151333, 1151332, 1151329, 1151331, 1151330, 1151328, 1151327, 1151326, 1151325, 1151322, 1151323, 1151321, 1151320, 1151319, 1151318, 1151316, 1151317, 1151313, 1151314, 1151312, 1151309, 1151306, 1151304, 1151305, 645462, 1151303, 1151301, 1151300, 1151297, 1151299, 1151298, 1151296, 1151295, 1151294, 1151293, 1151291, 1151285, 1151290, 1151289, 1151288, 1151287, 1151286, 1151275, 1151281, 1151274, 1151273, 1151272, 1151271, 1151270, 1151268, 1151269, 1151267, 1151266, 1151265, 1151262, 1151263, 1151261, 1151260, 1151258, 1151257, 1151256, 1151253, 1151252, 1151255, 1151254 Clostridium difficile, Clostridium difficile 630, Clostridium difficile F665, Clostridium difficile P53, Clostridium difficile P68, Clostridium difficile P64, Clostridium difficile P37, Clostridium difficile DA00130, Clostridium difficile P33, Clostridium difficile P41, Clostridium difficile CD86, Clostridium difficile CD88, Clostridium difficile CD127, Clostridium difficile P31, Clostridium difficile P30, Clostridium difficile CD111, Clostridium difficile CD92, Clostridium difficile CD113, Clostridium difficile CD90, Clostridium difficile F601, Clostridium difficile F548, Clostridium difficile F200, Clostridium difficile F525, Clostridium difficile F480, Clostridium difficile P77, Clostridium difficile P75, Clostridium difficile P74, Clostridium difficile P73, Clostridium difficile P71, Clostridium difficile P72, Clostridium difficile P70, Clostridium difficile P69, Clostridium difficile P78, Clostridium difficile P61, Clostridium difficile P51, Clostridium difficile P49, Clostridium difficile P50, Clostridium difficile P48, Clostridium difficile P46, Clostridium difficile P45, Clostridium difficile P36, Clostridium difficile P38, Clostridium difficile P42, Clostridium difficile P32, Clostridium difficile P24, Clostridium difficile P25, Clostridium difficile P23, Clostridium difficile P20, Clostridium difficile P21, Clostridium difficile P19, Clostridium difficile P15, Clostridium difficile P9, Clostridium difficile P11, Clostridium difficile P13, Clostridium difficile P8, Clostridium difficile P7, Clostridium difficile P5, Clostridium difficile P3, Clostridium difficile P2, Clostridium difficile Y384, Clostridium difficile Y401, Clostridium difficile P1, Clostridium difficile Y381, Clostridium difficile Y343, Clostridium difficile Y307, Clostridium difficile Y312, Clostridium difficile Y266, Clostridium difficile Y270, Clostridium difficile Y247, Clostridium difficile Y202, Clostridium difficile Y184, Clostridium difficile Y171, Clostridium difficile Y165, Clostridium difficile Y155, Clostridium difficile Y41, Clostridium difficile Y21, Clostridium difficile F253, Clostridium difficile Y10, Clostridium difficile F314, Clostridium difficile F501, Clostridium difficile F249, Clostridium difficile F152, Clostridium difficile DA00310, Clostridium difficile DA00313, Clostridium difficile DA00307, Clostridium difficile DA00305, Clostridium difficile DA00256, Clostridium difficile DA00306, Clostridium difficile DA00273, Clostridium difficile DA00245, Clostridium difficile DA00246, Clostridium difficile DA00216, Clostridium difficile DA00244, Clostridium difficile DA00238, Clostridium difficile DA00232, Clostridium difficile DA00215, Clostridium difficile DA00211, Clostridium difficile DA00212, Clostridium difficile DA00210, Clostridium difficile DA00203, Clostridium difficile DA00195, Clostridium difficile DA00197, Clostridium difficile DA00196, Clostridium difficile DA00189, Clostridium difficile DA00193, Clostridium difficile DA00191, Clostridium difficile DA00174, Clostridium difficile DA00183, Clostridium difficile DA00167, Clostridium difficile DA00160, Clostridium difficile DA00154, Clostridium difficile DA00142, Clostridium difficile DA00149, Clostridium difficile DA00145, Clostridium difficile DA00141, Clostridium difficile DA00134, Clostridium difficile DA00132, Clostridium difficile DA00131, Clostridium difficile DA00128, Clostridium difficile DA00129, Clostridium difficile DA00126, Clostridium difficile DA00114, Clostridium difficile DA00065, Clostridium difficile DA00062, Clostridium difficile 6057, Clostridium difficile DA00044, Clostridium difficile 6041, Clostridium difficile 6042, Clostridium difficile 842, Clostridium difficile 824, Clostridium difficile 342, Clostridium difficile CD211, Clostridium difficile CD212, Clostridium difficile CD196, Clostridium difficile CD206, Clostridium difficile CD201, Clostridium difficile CD200, Clostridium difficile CD175, Clostridium difficile CD181, Clostridium difficile CD178, Clostridium difficile CD170, Clostridium difficile CD169, Clostridium difficile CD166, Clostridium difficile CD165, Clostridium difficile CD159, Clostridium difficile CD129, Clostridium difficile CD149, Clostridium difficile CD144, Clostridium difficile CD133, Clostridium difficile CD132, Clostridium difficile CD131, Clostridium difficile CD70, Clostridium difficile CD109, Clostridium difficile CD69, Clostridium difficile CD68, Clostridium difficile CD51, Clostridium difficile CD49, Clostridium difficile CD47, Clostridium difficile CD45, Clostridium difficile CD46, Clostridium difficile CD44, Clostridium difficile CD43, Clostridium difficile CD42, Clostridium difficile CD39, Clostridium difficile CD40, Clostridium difficile CD38, Clostridium difficile CD34, Clostridium difficile CD21, Clostridium difficile CD18, Clostridium difficile CD17, Clostridium difficile CD8, Clostridium difficile CD3, Clostridium difficile CD13, Clostridium difficile CD9 Bacteria UP000058232, UP000032222, UP000016850, UP000016867, UP000016845, UP000016861, UP000016859, UP000016866, UP000016864, UP000016857, UP000015783, UP000015749, UP000015851, UP000015829, UP000015898, UP000015826, UP000015876, UP000015687, UP000015808, UP000015883, UP000015670, UP000015651, UP000015868, UP000015797, UP000015698, UP000015867, UP000015844, UP000015809, UP000015784, UP000015661, UP000015870, UP000015647, UP000015718, UP000015840, UP000015878, UP000015832, UP000015701, UP000015752, UP000015672, UP000015774, UP000015656, UP000015674, UP000015668, UP000015820, UP000015655, UP000015706, UP000015719, UP000015696, UP000015769, UP000015709, UP000015667, UP000015642, UP000015666, UP000015705, UP000015886, UP000015708, UP000015821, UP000015743, UP000015689, UP000015710, UP000015716, UP000015739, UP000015901, UP000015881, UP000015691, UP000015733, UP000015758, UP000015731, UP000015880, UP000015872, UP000015693, UP000015882, UP000015715, UP000015780, UP000015649, UP000015859, UP000015817, UP000015764, UP000015751, UP000015712, UP000015846, UP000015685, UP000015799, UP000015823, UP000015884, UP000015755, UP000015853, UP000015787, UP000015897, UP000015865, UP000015790, UP000015807, UP000015781, UP000015842, UP000015713, UP000015678, UP000015746, UP000015762, UP000015697, UP000015874, UP000015848, UP000015871, UP000015824, UP000015850, UP000015648, UP000015763, UP000015650, UP000015646, UP000015679, UP000015773, UP000015725, UP000015864, UP000015690, UP000015776, UP000015852, UP000015707, UP000015726, UP000015819, UP000015818, UP000015745, UP000015732, UP000015703, UP000015887, UP000015815, UP000015869, UP000015830, UP000015778, UP000015890, UP000015735, UP000015742, UP000015721, UP000015789, UP000015761, UP000015885, UP000015879, UP000015728, UP000015723, UP000015714, UP000015785, UP000015730, UP000015892, UP000015757, UP000015877, UP000015644, UP000015680, UP000015640, UP000015858, UP000015766, UP000015686, UP000015727, UP000015756, UP000015653, UP000015770, UP000015738, UP000015847, UP000015660, UP000015659, UP000015717, UP000015683, UP000015673, UP000015699, UP000015658, UP000015903, UP000015772, UP000015810, UP000015839, UP000015702, UP000015782, UP000015788, UP000015863, UP000015767, UP000015841, UP000015662, UP000015900 497575449, 126699308, 767026630, 612404078, 548679597, 548678993, 548673575, 548668857, 548666194, 548662351, 548657643, 548657155, 531880396, 531879066, 531818102, 531813991, 531813600, 531803889, 531803867, 531800418, 531794080, 531790334, 531783880, 531782581, 531777761, 531774888, 531763626, 531758627, 531756257, 531752371, 531747408, 531743224, 531741742, 531736326, 531730496, 531724820, 531720456, 531714929, 531714310, 531707463, 531703951, 531702909, 531695604, 531691948, 531691224, 531683165, 531671638, 531669331, 531663875, 531659671, 531658774, 531652949, 531646000, 531645114, 531643119, 531639960, 531632505, 531629954, 531618092, 531612723, 531607924, 531604481, 531601787, 531600847, 531592982, 531586079, 531581963, 531577616, 531577107, 531570189, 531564886, 531558560, 531555271, 531546031, 531544202, 531540651, 531534147, 531528075, 531524621, 531520991, 531515829, 531514427, 531509385, 531503481, 531499534, 531497883, 531496136, 531490076, 531484076, 531483987, 531477175, 531464567, 531459302, 531456155, 531451316, 531450988, 531446899, 531439600, 531434158, 531432904, 531429585, 531422047, 531418587, 531418242, 531413229, 531406165, 531405066, 531401539, 531393741, 531392477, 531389217, 531378707, 531374845, 531372576, 531368498, 531365346, 531360118, 531353501, 531351340, 531349973, 531343279, 531342231, 531335924, 531332762, 531326824, 531326326, 531317253, 531317004, 531309106, 531305732, 531300240, 531296023, 531285869, 531283705, 531279440, 531273671, 531272788, 531272652, 531264229, 531260172, 531256243, 531253986, 531246544, 531240543, 531237345, 531232080, 531227543, 531222019, 531218324, 531214184, 531209957, 531205991, 531202306, 531194893, 531194313, 531183118, 531177874, 531175644, 531173338, 531167804, 531161879, 531160048, 531159034, 531150723, 531149501, 531144882, 531136708, 531131986, 531128685, 531120735, 531115101, 531114060, 531106189, 531104914, 531104891, 531098851, 733569230, 123174240, 115250745 KJF64584.1, EZR30087.1, ERM48810.1, ERM48213.1, ERM42871.1, ERM38237.1, ERM35617.1, ERM31843.1, ERM27237.1, ERM26754.1, EQL09495.1, EQL08205.1, EQK92366.1, EQK88626.1, EQK88237.1, EQK79254.1, EQK79237.1, EQK75975.1, EQK69933.1, EQK66311.1, EQK59942.1, EQK58661.1, EQK53891.1, EQK51037.1, EQK39907.1, EQK34994.1, EQK32655.1, EQK28809.1, EQK23928.1, EQK19795.1, EQK18330.1, EQK12979.1, EQK07243.1, EQK01646.1, EQJ97350.1, EQJ91887.1, EQJ91270.1, EQJ84528.1, EQJ81070.1, EQJ80034.1, EQJ72842.1, EQJ69233.1, EQJ68515.1, EQJ60589.1, EQJ49229.1, EQJ46941.1, EQJ41557.1, EQJ37404.1, EQJ36522.1, EQJ30809.1, EQJ24068.1, EQJ23200.1, EQJ21250.1, EQJ18196.1, EQJ11064.1, EQJ08670.1, EQI97499.1, EQI92420.1, EQI87861.1, EQI84636.1, EQI82119.1, EQI81243.1, EQI73797.1, EQI67088.1, EQI63065.1, EQI58994.1, EQI58511.1, EQI51923.1, EQI46837.1, EQI40780.1, EQI37726.1, EQI29192.1, EQI27551.1, EQI24283.1, EQI18068.1, EQI12347.1, EQI09121.1, EQI05716.1, EQI00757.1, EQH99378.1, EQH94675.1, EQH89026.1, EQH85229.1, EQH83686.1, EQH82054.1, EQH76745.1, EQH71369.1, EQH71288.1, EQH65202.1, EQH53124.1, EQH48207.1, EQH45186.1, EQH40635.1, EQH40326.1, EQH36463.1, EQH29569.1, EQH24362.1, EQH23151.1, EQH19937.1, EQH12710.1, EQH09290.1, EQH08947.1, EQH04009.1, EQG97204.1, EQG96155.1, EQG92732.1, EQG85410.1, EQG84215.1, EQG81095.1, EQG70889.1, EQG67125.1, EQG64938.1, EQG60988.1, EQG57921.1, EQG52856.1, EQG46416.1, EQG44291.1, EQG42952.1, EQG36422.1, EQG35403.1, EQG29244.1, EQG26152.1, EQG20821.1, EQG20343.1, EQG11739.1, EQG11513.1, EQG04063.1, EQG00868.1, EQF95614.1, EQF91573.1, EQF82074.1, EQF80014.1, EQF75937.1, EQF70370.1, EQF69515.1, EQF69384.1, EQF61612.1, EQF58199.1, EQF54591.1, EQF52416.1, EQF45788.1, EQF40261.1, EQF37576.1, EQF32490.1, EQF28200.1, EQF22912.1, EQF19434.1, EQF15427.1, EQF11343.1, EQF07595.1, EQF04076.1, EQE97254.1, EQE96702.1, EQE85906.1, EQE80814.1, EQE78637.1, EQE76406.1, EQE71099.1, EQE65391.1, EQE63607.1, EQE62621.1, EQE54642.1, EQE53467.1, EQE49018.1, EQE41081.1, EQE36503.1, EQE33294.1, EQE25579.1, EQE20135.1, EQE19120.1, EQE11644.1, EQE10425.1, EQE10403.1, EQE04511.1 WP_009889633.1, YP_001088205.1 Q186R0 THIC_PEPD6 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7750022, 3938635, 4931887, 7753527, 4923958, 4927063, 4917821, 3374143 fig|479834.4.peg.1171, fig|499176.4.peg.1292, fig|997828.4.peg.3746, fig|1121308.3.peg.2154, fig|691160.5.peg.2264, fig|1496.1.peg.1670, fig|645463.3.peg.1705, fig|479832.7.peg.1316, fig|645462.3.peg.1703, fig|272563.8.peg.1780, fig|367459.5.peg.819, fig|479833.4.peg.1315, fig|1125976.4.peg.3482, fig|455631.3.peg.3557, fig|699037.5.peg.1845, fig|699033.6.peg.1737, fig|479831.4.peg.953, fig|699036.5.peg.1775, fig|699034.5.peg.1734, fig|997827.4.peg.3100, fig|499175.4.peg.1345, fig|691161.5.peg.1456, fig|1002369.4.peg.2802 433 433 yes 437776 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 561, 562, 439184, 1329907, 866789, 1438673, 1400158, 1400159, 1281141, 1281081, 1281107, 1280965, 1269004, 1281236, 1281137, 1281274, 1281272, 1281265, 1281259, 1281256, 1281215, 1281216, 1281200, 1281190, 1281176, 1281157, 1281148, 1281144, 1281138, 1281130, 1281128, 1281126, 1281123, 1281119, 1281118, 1281108, 1281100, 1281070, 1281062, 1281061, 1281055, 1281040, 1281038, 1281018, 1281014, 1281012, 1281005, 1280997, 1280992, 1280985, 1280983, 1280981, 1280970, 1280960, 1280956, 1280958, 1181782, 1169346, 1169316, 1169317, 1169404, 1169403, 1169401, 1181773, 1181775, 1182712, 1182709, 1182672, 1182666, 1169341, 1182669, 1182665, 1182662, 1169326, 1169325, 752789, 656398, 656390, 656388, 749536, 869729, 714962, 469598, 405955, 1382700, 585035 Escherichia coli, Escherichia coli RS218, Escherichia coli APEC IMT5155, Escherichia coli DSM 30083, Escherichia coli BIDMC 65, Escherichia coli BIDMC 49a, Escherichia coli BIDMC 49b, Escherichia coli HVH 214 (4-3062198), Escherichia coli HVH 148 (4-3192490), Escherichia coli HVH 178 (4-3189163), Escherichia coli HVH 12 (4-7653042), Escherichia coli 908675, Escherichia coli UMEA 3298-1, Escherichia coli HVH 210 (4-3042480), Escherichia coli UMEA 3893-1, Escherichia coli UMEA 3834-1, Escherichia coli UMEA 3702-1, Escherichia coli UMEA 3662-1, Escherichia coli UMEA 3632-1, Escherichia coli UMEA 3203-1, Escherichia coli UMEA 3206-1, Escherichia coli UMEA 3162-1, Escherichia coli UMEA 3140-1, Escherichia coli UMEA 3041-1, Escherichia coli KOEGE 32 (66a), Escherichia coli HVH 222 (4-2977443), Escherichia coli HVH 217 (4-1022806), Escherichia coli HVH 211 (4-3041891), Escherichia coli HVH 203 (4-3126218), Escherichia coli HVH 201 (4-4459431), Escherichia coli HVH 199 (4-5670322), Escherichia coli HVH 196 (4-4530470), Escherichia coli HVH 192 (4-3054470), Escherichia coli HVH 191 (3-9341900), Escherichia coli HVH 180 (4-3051617), Escherichia coli HVH 170 (4-3026949), Escherichia coli HVH 137 (4-2124971), Escherichia coli HVH 127 (4-7303629), Escherichia coli HVH 126 (4-6034225), Escherichia coli HVH 118 (4-7345399), Escherichia coli HVH 104 (4-6977960), Escherichia coli HVH 102 (4-6906788), Escherichia coli HVH 80 (4-2428830), Escherichia coli HVH 76 (4-2538717), Escherichia coli HVH 73 (4-2393174), Escherichia coli HVH 59 (4-1119338), Escherichia coli HVH 48 (4-2658593), Escherichia coli HVH 42 (4-2100061), Escherichia coli HVH 35 (4-2962667), Escherichia coli HVH 32 (4-3773988), Escherichia coli HVH 30 (4-2661829), Escherichia coli HVH 19 (4-7154984), Escherichia coli HVH 5 (4-7148410), Escherichia coli HVH 1 (4-6876161), Escherichia coli HVH 3 (4-7276001), Escherichia coli KTE240, Escherichia coli KTE27, Escherichia coli KTE3, Escherichia coli KTE7, Escherichia coli KTE180, Escherichia coli KTE179, Escherichia coli KTE176, Escherichia coli KTE227, Escherichia coli KTE229, Escherichia coli KTE123, Escherichia coli KTE118, Escherichia coli KTE65, Escherichia coli KTE59, Escherichia coli KTE22, Escherichia coli KTE62, Escherichia coli KTE58, Escherichia coli KTE55, Escherichia coli KTE5, Escherichia coli KTE4, Escherichia coli HM605, Escherichia coli H397, Escherichia coli H263, Escherichia coli H252, Escherichia coli MS 110-3, Escherichia coli UM146, Escherichia coli IHE3034, Escherichia sp. 3_2_53FAA, Escherichia coli APEC O1, Escherichia coli PMV-1, Escherichia coli S88 Bacteria UP000036210, UP000031571, UP000031137, UP000028628, UP000027514, UP000022594, UP000021697, UP000018671, UP000017770, UP000017750, UP000017754, UP000017484, UP000016263, UP000015998, UP000016158, UP000016114, UP000016083, UP000016152, UP000016429, UP000016031, UP000016329, UP000016035, UP000016324, UP000016299, UP000016091, UP000016000, UP000016092, UP000016351, UP000016017, UP000016042, UP000016146, UP000016397, UP000016025, UP000016277, UP000016006, UP000016371, UP000016129, UP000016151, UP000016352, UP000016328, UP000015991, UP000016465, UP000016401, UP000016257, UP000016009, UP000016119, UP000016290, UP000016061, UP000016245, UP000016157, UP000016340, UP000016289, UP000016128, UP000016365, UP000016063, UP000014094, UP000014195, UP000014080, UP000014166, UP000010633, UP000010718, UP000010693, UP000010642, UP000010591, UP000010588, UP000010717, UP000010522, UP000010611, UP000010499, UP000010514, UP000010687, UP000010597, UP000010629, UP000010594, UP000004147, UP000006259, UP000004345, UP000004498, UP000004767, UP000006682, UP000002364, UP000005767, UP000008216, UP000016705, UP000000747 485698311, 838814655, 767820374, 756771917, 746684353, 746673982, 742675062, 668705048, 635816189, 575657992, 575654714, 565515773, 556147961, 556140228, 556125018, 553703339, 536031093, 535984983, 535884357, 535884220, 535841588, 535817563, 535814158, 535659936, 535657533, 535582515, 535560806, 535488101, 535395723, 535362999, 535345975, 535322192, 535287038, 535275925, 535263246, 535253794, 535235186, 535229766, 535179097, 535154231, 535036938, 535002181, 534996561, 534964695, 534896390, 534885600, 534831735, 534806367, 534794332, 534754496, 534724923, 534700912, 534671033, 534662924, 534655301, 534606100, 534564994, 534544562, 534542671, 508537356, 508308842, 508254248, 508253612, 431682894, 431682544, 431669080, 431521003, 431520381, 431376927, 431372269, 431334629, 431323635, 431298976, 431127160, 431116581, 431103725, 430882767, 430872454, 388421464, 371601646, 323953794, 323948835, 315288339, 307628389, 294490271, 226903074, 115515380, 777222622, 544343599, 226695847, 218367829, 166228031 KLX96864.1, KJH00961.1, AJM76188.1, KIE75523.1, KIE65315.1, AJB37249.1, KFB90995.1, KDF97425.1, ETY56546.1, ETY53306.1, ETF27628.1, ESP36199.1, ESP28551.1, ESP13540.1, ESE18956.1, ERB29987.1, ERA84729.1, ERA15720.1, ERA15586.1, EQZ73747.1, EQZ50078.1, EQZ46728.1, EQX95832.1, EQX93502.1, EQX19919.1, EQW98567.1, EQW27483.1, EQV37325.1, EQV05243.1, EQU88455.1, EQU64975.1, EQU30114.1, EQU19112.1, EQU06602.1, EQT97313.1, EQT78997.1, EQT73382.1, EQT23568.1, EQS99012.1, EQR84053.1, EQR50163.1, EQR44670.1, EQR13240.1, EQQ46220.1, EQQ35647.1, EQP82848.1, EQP58297.1, EQP46666.1, EQP07351.1, EQO78245.1, EQO56507.1, EQO27095.1, EQO19111.1, EQO11594.1, EQN63157.1, EQN24394.1, EQN04185.1, EQN02305.1, EOX05726.1, EOU81164.1, EOU27639.1, EOU27005.1, ELJ48540.1, ELJ48307.1, ELJ35515.1, ELH98254.1, ELH97707.1, ELG62066.1, ELG57932.1, ELG21787.1, ELG11112.1, ELF88598.1, ELE29470.1, ELE20019.1, ELE08362.1, ELC05840.1, ELB96059.1, EIL81079.1, EHN90377.1, EGB49601.1, EGB44732.1, EFU47738.1, ADN72693.1, ADE89027.1, EEH89333.1, ABJ03455.1 WP_001331778.1 B7MIY0, A1AIG5 THIC_ECO45, THIC_ECOK1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2097761, 5872610, 1237580 fig|1169325.3.peg.4563, fig|405955.13.peg.4463, fig|749536.3.peg.1533, fig|1181775.3.peg.3034, fig|1182672.3.peg.4309, fig|1181773.3.peg.566, fig|1182662.3.peg.5137, fig|656388.3.peg.4996, fig|1169326.3.peg.4430, fig|1169341.3.peg.4113, fig|1169404.3.peg.4372, fig|1169403.3.peg.4336, fig|656390.3.peg.5068, fig|1182712.3.peg.1650, fig|469598.5.peg.4847, fig|1182666.3.peg.5035, fig|869729.3.peg.3569, fig|1169346.3.peg.1404, fig|585035.6.peg.4362, fig|1181782.3.peg.4373, fig|714962.3.peg.4500, fig|752789.3.peg.1933, fig|1169401.3.peg.4300, fig|656398.3.peg.5083, fig|1182669.3.peg.5051, fig|1169316.3.peg.4976, fig|1169317.3.peg.5262, fig|1182665.3.peg.5030, fig|1182709.3.peg.396, fig|364106.7.peg.3745 626 631 yes 437777 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 216465, 365044 Polaromonas naphthalenivorans, Polaromonas naphthalenivorans CJ2 Bacteria UP000000644 500123450, 120591906, 229558534 ABM35345.1 WP_011799455.1 A1VI67 THIC_POLNA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1998506 fig|365044.20.peg.823 637 638 yes 437778 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28049, 351607 Acidothermus cellulolyticus, Acidothermus cellulolyticus 11B Bacteria UP000008221 500038174, 117647726 ABK51828.1 WP_011718892.1 fig|351607.5.peg.52 579 585 yes 437779 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 391612 Cyanothece sp. CCY0110 Bacteria UP000003781 495548982, 126623335 EAZ94040.1 WP_008273561.1 fig|391612.3.peg.431 459 459 yes 437780 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 60480 Shewanella sp. MR-4 Bacteria UP000008079 499941918, 113884903 ABI38955.1 WP_011622652.1 fig|60480.16.peg.1791 674 720 yes 437781 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 487, 1386084, 1095685, 1145149, 1145148, 1145147, 1145146, 1145180, 1145179, 1145173, 1145175, 1145174, 1145172, 1145171, 1145170, 1145169, 1145166, 1145165, 1145164, 1145163, 1145156, 1145155, 1145154, 1145152, 1145153, 1145151, 1145150, 1145145, 1095683, 1095684, 1095686, 1095687, 1095688, 935586, 272831 Neisseria meningitidis, Neisseria meningitidis LNP27256, Neisseria meningitidis M7124, Neisseria meningitidis NM36, Neisseria meningitidis NM35, Neisseria meningitidis NM32, Neisseria meningitidis NM23, Neisseria meningitidis 2008223, Neisseria meningitidis 2005172, Neisseria meningitidis 2001068, Neisseria meningitidis 2002004, Neisseria meningitidis 2005040, Neisseria meningitidis 2005079, Neisseria meningitidis 2000175, Neisseria meningitidis 2004264, Neisseria meningitidis 2001213, Neisseria meningitidis 2000081, Neisseria meningitidis 2001073, Neisseria meningitidis 2001072, Neisseria meningitidis NM3147, Neisseria meningitidis NM1495, Neisseria meningitidis NM1482, Neisseria meningitidis NM313, Neisseria meningitidis NM94, Neisseria meningitidis NM95, Neisseria meningitidis NM82, Neisseria meningitidis NM43, Neisseria meningitidis NM133, Neisseria meningitidis NM126, Neisseria meningitidis NM174, Neisseria meningitidis M7089, Neisseria meningitidis NM762, Neisseria meningitidis NM586, Neisseria meningitidis ES14902, Neisseria meningitidis FAM18 Bacteria UP000050419, UP000031267, UP000010748, UP000013354, UP000013376, UP000013313, UP000013366, UP000013320, UP000013364, UP000014584, UP000013347, UP000013360, UP000013318, UP000013346, UP000013383, UP000013317, UP000013348, UP000013325, UP000013379, UP000013341, UP000013375, UP000013634, UP000013389, UP000013338, UP000013329, UP000013373, UP000013332, UP000013370, UP000010740, UP000010763, UP000010768, UP000010767, UP000010758, UP000005973, UP000002286 488153483, 743393013, 730580104, 730578813, 730576210, 730572091, 730570542, 723270829, 694192245, 485434824, 485434062, 485429829, 485428828, 485391954, 485390167, 485387611, 485385643, 485385454, 485381839, 485379259, 485378745, 485372997, 485366287, 485364685, 485363617, 485360117, 485343668, 485341514, 485340928, 485336844, 485336711, 485335623, 485330931, 485327280, 432238136, 432232719, 432232332, 432231543, 432227102, 432225543, 325137313, 166228049, 120867405 KID52552.1, AIZ26085.1, AIZ25260.1, AIZ23159.1, AIZ19493.1, AIZ18344.1, KHC98020.1, KGI97529.1, EOC90141.1, EOC89456.1, EOC85630.1, EOC84737.1, EOC50487.1, EOC48843.1, EOC46439.1, EOC44593.1, EOC44416.1, EOC41047.1, EOC38632.1, EOC38145.1, EOC32765.1, EOC26515.1, EOC25039.1, EOC24068.1, EOC20900.1, EOC05678.1, EOC03686.1, EOC03138.1, EOB99300.1, EOB99173.1, EOB98175.1, EOB93796.1, EOB90394.1, ELK93712.1, ELK88355.1, ELK87977.1, ELK87202.1, ELK82814.1, ELK81284.1, EGC59901.1 WP_002224691.1 A1KWC0 THIC_NEIMF Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1793003 fig|1145148.3.peg.2595, fig|1095688.3.peg.2733, fig|1145145.3.peg.2664, fig|1145173.3.peg.661, fig|487.2.peg.1404, fig|1095683.3.peg.2653, fig|1145147.3.peg.2442, fig|768484.3.peg.675, fig|1145179.3.peg.2624, fig|1145154.3.peg.2599, fig|1095687.3.peg.2609, fig|272831.7.peg.2527, fig|768485.3.peg.1606, fig|1145172.3.peg.1567, fig|1145171.3.peg.2638, fig|1145150.3.peg.2504, fig|1145165.3.peg.2599, fig|1145163.3.peg.2642, fig|1145169.3.peg.2543, fig|1145146.3.peg.2627, fig|1145149.3.peg.2537, fig|935587.3.peg.2617, fig|935586.3.peg.2613, fig|1145151.3.peg.2226, fig|1095686.3.peg.2652, fig|1145164.3.peg.2571, fig|1145153.3.peg.2646, fig|1145155.3.peg.2544, fig|1145166.3.peg.2616, fig|1095684.3.peg.2602, fig|1145175.3.peg.2664, fig|1095685.3.peg.2624, fig|1145174.3.peg.2611, fig|1145152.3.peg.1714, fig|1145180.3.peg.2587, fig|1145170.3.peg.1723, fig|1145156.3.peg.2568 625 633 yes 437782 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 261685, 401526 Thermosinus carboxydivorans, Thermosinus carboxydivorans Nor1 Bacteria UP000005139 494499209, 121307511 EAX48427.1 WP_007288675.1 fig|401526.3.peg.811 432 433 yes 437783 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1027, 313606 Microscilla marina, Microscilla marina ATCC 23134 Bacteria UP000004095 488784681, 123989369 EAY28930.1 WP_002697088.1 fig|313606.3.peg.3012 619 619 yes 437784 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 83984, 410358 Methanocorpusculum labreanum, Methanocorpusculum labreanum Z Archaea UP000000365 500159405, 124364064, 166228039 ABN07872.1 WP_011834075.1 A2SU66 THIC_METLZ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2104086 fig|410358.8.peg.1724 420 425 yes 437785 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 41, 378806 Stigmatella aurantiaca, Stigmatella aurantiaca DW4/3-1 Bacteria UP000001351 488688773, 309395011, 115368558 ADO72470.1, EAU67511.1 WP_002612974.1 fig|378806.7.peg.2645 621 624 yes 437786 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1159328, 419542 Leptospirillum sp. Group II 'C75', Leptospirillum rubarum Bacteria UP000016760 387222411, 124515720 EIJ76860.1, EAY57229.1 462 468 yes 437787 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1428, 412694 Bacillus thuringiensis, Bacillus thuringiensis str. Al Hakam Bacteria UP000031834, UP000000761 446737209, 753587609, 118419491, 166228012 AJH66459.1, ABK87910.1 WP_000814465.1 A0RL17 THIC_BACAH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2120294 fig|412694.5.peg.4543 586 586 yes 437788 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 59753, 1435973, 1113728, 393595 Alcanivorax sp. 97CO-5, Alcanivorax sp. NBRC 101098, Alcanivorax borkumensis SK2 Bacteria UP000019144, UP000033280, UP000008871 499909037, 576998760, 662234490, 110648471 EUC71017.1 WP_011589771.1 fig|393595.12.peg.2504 621 624 yes 437789 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 399742 Enterobacter sp. 638 Bacteria UP000000230 500264587, 145316750 ABP58897.1 WP_011915471.1 fig|399742.10.peg.335 626 630 yes 437790 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1219, 167555 Prochlorococcus marinus, Prochlorococcus marinus str. NATL1A Bacteria UP000002592 500148563, 123961836, 166228053 ABM76619.1 WP_011824566.1 A2C559 THIC_PROM1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1215212 fig|167555.5.peg.2108 464 466 yes 437791 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 666, 412883 Vibrio cholerae, Vibrio cholerae MZO-3 Bacteria UP000028983, UP000005482 487823868, 124122776 EAY41519.1 WP_001897334.1 fig|412883.10.peg.1409 639 645 yes 437792 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 916, 335283 Nitrosomonas eutropha, Nitrosomonas eutropha C91 Bacteria UP000001966 499952593, 114307239, 122314715 ABI58482.1 WP_011633327.1 Q0AJI9 THIC_NITEC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1897368 fig|335283.5.peg.322 628 632 yes 437793 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 774, 1293907, 1293909, 1293908, 1427332, 1427333, 1206782, 360095 Bartonella bacilliformis, Bartonella bacilliformis CAR600-02, Bartonella bacilliformis VAB9028, Bartonella bacilliformis Hosp800-02, Bartonella bacilliformis str. Heidi Mejia, Bartonella bacilliformis San Pedro600-02, Bartonella bacilliformis INS, Bartonella bacilliformis KC583 Bacteria UP000059456, UP000027403, UP000031735, UP000031734, UP000020764, UP000023366, UP000009359, UP000000643 492159503, 657182863, 657182512, 657177361, 601445158, 601442928, 411174986, 120614637, 166228013 KEG24118.1, KEG23769.1, KEG18661.1, EYS92268.1, EYS90104.1, EKS45013.1, ABM45238.1 WP_005766492.1 A1US11 THIC_BARBK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1976739 fig|360095.6.peg.428, fig|1206782.3.peg.439, fig|360095.3.peg.144 602 611 yes 437794 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 74318, 394221 Maricaulis maris, Maricaulis maris MCS10 Bacteria UP000001964 499961791, 114339582 ABI64862.1 WP_011642509.1 fig|394221.5.peg.552 615 623 yes 437795 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 312153 Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1 Bacteria UP000000231 145047485 ABP34112.1 fig|312153.3.peg.922 641 647 yes 437796 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 359303, 323850 Shewanella loihica, Shewanella loihica PV-4 Bacteria UP000001558 500192687, 126638319, 189030298 ABO23962.1 WP_011865894.1 A3QER4 THIC_SHELP Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5209639 fig|323850.3.peg.1809, fig|323850.11.peg.2095 646 683 yes 437797 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2234, 1344584, 224325 Archaeoglobus fulgidus, Archaeoglobus fulgidus DSM 8774, Archaeoglobus fulgidus DSM 4304 Archaea UP000054307, UP000028501, UP000002199 499182359, 668357309, 2650682, 7388298 AIG99380.1, AAB91254.1 WP_010879899.1 O30259, A0A075WG68 THIC_ARCFU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} A0A075WG68_ARCFL 24269 fig|257309.1.peg.172, fig|224325.1.peg.2396 425 425 yes 437798 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 120793, 44454, 1299329, 1299330, 1402966, 1402967, 1160712, 1160711, 1427296, 1335321, 1335419, 1392000, 243243, 1229671 Mycobacterium avium subsp. avium, Mycobacterium avium 2285 (S), Mycobacterium avium 2285 (R), Mycobacterium avium subsp. hominissuis 100, Mycobacterium avium subsp. hominissuis 101, Mycobacterium avium subsp. hominissuis 3388, Mycobacterium avium subsp hominissuis A5, Mycobacterium tuberculosis XTB13-223, Mycobacterium sp. MAC_011194_8550, Mycobacterium avium MAV_120709_2344, Mycobacterium avium 10-5581, Mycobacterium avium 104, Mycobacterium avium subsp. hominissuis TH135 Bacteria UP000030084, UP000031751, UP000029489, UP000027045, UP000027108, UP000027031, UP000027224, UP000025919, UP000022168, UP000021340, UP000018557, UP000001574, UP000016440 497665203, 701192332, 690329057, 690309307, 643003137, 643001491, 642993116, 642992833, 624201337, 576382415, 576361633, 564148793, 118166781, 508736783, 166228045 AIV26968.1, AIR25802.1, AIR58616.1, KDP03299.1, KDP01701.1, KDO93561.1, KDO93281.1, KBR62294.1, ETZ76448.1, ETZ55970.1, ETA93687.1, ABK67678.1 WP_009979387.1 A0QLS0 THIC_MYCA1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2232477 fig|553481.3.peg.4129, fig|243243.5.peg.4641, fig|1078011.3.peg.2277 538 540 yes 437799 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 357794, 357804 Psychromonas ingrahamii, Psychromonas ingrahamii 37 Bacteria UP000000639 500092768, 119862745 ABM02222.1 WP_011768781.1 fig|357804.5.peg.347 642 656 yes 437800 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1094, 290318 Chlorobium phaeovibrioides, Chlorobium phaeovibrioides DSM 265 Bacteria UP000006700 500220391, 145206242, 189030278 ABP37285.1 WP_011890508.1 A4SFM6 THIC_CHLPM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3401125 fig|290318.4.peg.1256 569 571 yes 437801 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 233413, 83332, 77643, 33892, 1773, 1765, 1452723, 1437856, 1516074, 1400897, 1448586, 1400885, 1400922, 1408972, 1400938, 1447450, 1427279, 1447473, 1447482, 1447488, 1447499, 1447503, 1447505, 1447506, 1447518, 1354157, 1354159, 1354156, 1354113, 1421968, 1448714, 1448655, 1448749, 1448773, 1448831, 1448827, 1423427, 1448835, 1423464, 1423473, 1423477, 1423495, 1423524, 1423569, 1438861, 1438850, 1438871, 1438847, 1438869, 1448436, 1448519, 1448537, 1455302, 1447445, 1455292, 1438854, 1249615, 1427258, 1427257, 1427256, 1427255, 1427254, 1427252, 1427251, 1427250, 1427249, 1427248, 1427245, 1427246, 1427244, 1427243, 1427242, 1427240, 1427241, 1427238, 1427239, 1427237, 1427236, 1427235, 1427233, 1427234, 1427230, 1427232, 1427228, 1427229, 1427227, 1427226, 1427224, 1427225, 1427222, 1427223, 1427221, 1427219, 1427218, 1427217, 1427216, 1427215, 1427212, 1427213, 1427211, 1427210, 1427209, 1427207, 1427208, 1427206, 1427205, 1427203, 1427204, 1427199, 1427200, 1427197, 1427196, 1427195, 1427193, 1427194, 1427192, 1427191, 1427190, 1427189, 1427188, 1427187, 1427186, 1427185, 1427183, 1427182, 1427180, 1427181, 1427179, 1423577, 1427178, 1427177, 1423576, 1423575, 1423573, 1423574, 1423572, 1423571, 1423570, 1423568, 1423566, 1423567, 1423565, 1423564, 1423563, 1423562, 1423561, 1423560, 1423559, 1423558, 1423557, 1423556, 1423555, 1423554, 1423553, 1423552, 1423551, 1423550, 1423549, 1423547, 1423546, 1423544, 1423545, 1423543, 1423542, 1423541, 1423540, 1423539, 1423538, 1423536, 1423537, 1423535, 1423533, 1423534, 1423531, 1423532, 1423530, 1423528, 1423529, 1423527, 1423526, 1423523, 1423522, 1423520, 1423518, 1423517, 1423516, 1423514, 1423511, 1423513, 1423510, 1423509, 1423508, 1423507, 1423505, 1423504, 1423503, 1423502, 1423501, 1423500, 1423499, 1423498, 1423496, 1423497, 1423494, 1423493, 1423492, 1423490, 1423489, 1423487, 1423488, 1423486, 1423485, 1423484, 1423483, 1423481, 1423482, 1423480, 1423479, 1423478, 1423476, 1423475, 1423474, 1423472, 1423471, 1423469, 1423470, 1423467, 1423468, 1423465, 1423466, 1423463, 1423461, 1423462, 1423460, 1423459, 1423457, 1423458, 1423456, 1423455, 1423454, 1423453, 1423452, 1423451, 1423450, 1423449, 1423448, 1423447, 1423446, 1423445, 1423444, 1423443, 1423442, 1423440, 1423441, 1423438, 1423439, 1423437, 1423436, 1423432, 1423435, 1423431, 1423430, 1423426, 1423428, 1423425, 1422113, 1422110, 1422112, 1422111, 1422108, 1422109, 1422107, 1422106, 1422105, 1422104, 1422100, 1422103, 1422097, 1422098, 1422096, 1422094, 1422095, 1422092, 1422093, 1422091, 1422090, 1422089, 1422088, 1422087, 1422085, 1422086, 1422084, 1422083, 1422082, 1422081, 1422080, 1422079, 1422078, 1422076, 1422077, 1422075, 1422074, 1422073, 1422072, 1422071, 1422070, 1422069, 1422068, 1422067, 1422066, 1422065, 1422064, 1422063, 1422060, 1422059, 1422057, 1422058, 1422055, 1422056, 1422054, 1422053, 1422052, 1422051, 1422050, 1422049, 1422047, 1422048, 1422046, 1422045, 1422044, 1422042, 1422043, 1422041, 1422036, 1422035, 1422034, 1422033, 1422029, 1422025, 1422024, 1422021, 1422020, 1422017, 1422016, 1422015, 1422014, 1422013, 1422012, 1422011, 1422010, 1422008, 1422009, 1422007, 1422006, 1422004, 1422005, 1422003, 1422002, 1422001, 1422000, 1421998, 1421997, 1421996, 1421995, 1408915, 1408914, 1408913, 1408912, 1408911, 1408909, 1408907, 1408905, 1408906, 1408904, 1402483, 1402480, 1402475, 1402473, 1400941, 1400939, 1400940, 1400937, 1400936, 1400934, 1400935, 1400932, 1400933, 1400930, 1400931, 1400929, 1400928, 1400927, 1400926, 1400925, 1400924, 1400923, 1400921, 1400918, 1400920, 1400916, 1400915, 1400914, 1400912, 1400911, 1400909, 1400907, 1400908, 1400904, 1400902, 1400899, 1400898, 1400895, 1400893, 1400894, 1400891, 1400889, 1400888, 1400887, 1400884, 1400886, 1400883, 1400882, 1400880, 1400881, 1400879, 1400877, 1400874, 1400875, 1400873, 1400872, 1400870, 1400871, 1397941, 1397938, 1397939, 1397937, 1397933, 1397932, 1397931, 1397930, 1397927, 1397928, 1397926, 1397923, 1397921, 1397922, 1397920, 1397918, 1397919, 1397917, 1397915, 1397914, 1397913, 1397912, 1397911, 1397909, 1397910, 1397908, 1397907, 1397906, 1397905, 1397904, 1397903, 1397901, 1397902, 1397900, 1397899, 1397897, 1397895, 1397896, 1397894, 1397893, 1397891, 1397892, 1397890, 1397889, 1397887, 1397886, 1397884, 1397885, 1397882, 1397883, 1397881, 1397880, 1397879, 1397877, 1397878, 1397876, 1397875, 1397874, 1397873, 1397872, 1397869, 1397871, 1397868, 1397867, 1397866, 1397864, 1397865, 1397863, 1397862, 1397861, 1397860, 1397859, 1397858, 1397857, 1397855, 1397856, 1397854, 1397853, 1423521, 1423525, 1423519, 1423515, 1423506, 1423512, 1324301, 1324299, 1324300, 1324298, 1324297, 1324295, 1324296, 1324294, 1324292, 1324293, 1324291, 1324290, 1324288, 1324289, 1324286, 1324287, 1324283, 1324285, 1324284, 1324282, 1324281, 1324280, 1324279, 1324278, 1324277, 1324276, 1324275, 1324273, 1324272, 1324270, 1324268, 1324266, 1324265, 1324264, 1324263, 1324262, 1324259, 1324260, 1324257, 1324258, 1324256, 1324254, 1324255, 1324253, 1324250, 1324251, 1324248, 1324249, 1324247, 1324244, 1324245, 1324243, 1324241, 1324242, 1324240, 1324238, 1324239, 1324236, 1324237, 1324235, 1324234, 1324233, 1324232, 1324231, 1324230, 1324229, 1324226, 1324228, 1324227, 1324224, 1324225, 1324222, 1324223, 1324220, 1324219, 1324221, 1324218, 1295808, 1295807, 1295806, 1295805, 1295804, 1295801, 1295802, 1295803, 1295800, 1295799, 1295798, 1295797, 1295796, 1295792, 1295791, 1295795, 1295781, 1295775, 1295776, 1295774, 1295773, 1295771, 1295772, 1295769, 1295766, 1295767, 1295763, 1295765, 1295764, 1295759, 1295760, 1295758, 1295757, 1295753, 1295751, 1295756, 1295747, 1295746, 1295745, 1295744, 1295742, 1295740, 1295726, 1295727, 1295739, 1295724, 1295725, 1295721, 1295723, 1267363, 1267364, 1295720, 1267362, 1267359, 1267360, 1267361, 1267358, 1267355, 1455311, 1267356, 1455312, 1455308, 1455295, 1455307, 1455305, 1455294, 1455293, 1455291, 1455286, 1455290, 1455289, 1455287, 1455288, 1455285, 1455283, 1455284, 1455279, 1455278, 1455275, 1455276, 1455273, 1455274, 1455272, 1455270, 1455269, 1455263, 1455268, 1455264, 1455266, 1448608, 1448609, 1448605, 1448607, 1448604, 1448602, 1448601, 1448600, 1448599, 1448597, 1448596, 1448594, 1448593, 1448595, 1448591, 1448592, 1438873, 1448590, 1448588, 1448589, 1438862, 1448587, 1438867, 1438877, 1438892, 1438879, 1438832, 1438834, 1438836, 1438841, 1438887, 1438839, 1438878, 1438881, 1427330, 1427329, 1427327, 1427325, 1427324, 1427322, 1427323, 1427321, 1427320, 1427319, 1427317, 1427318, 1427316, 1427314, 1427315, 1427313, 1427312, 1427311, 1427308, 1427310, 1427309, 1427306, 1427305, 1427307, 1427304, 1427303, 1427302, 1427301, 1427300, 1427299, 1427298, 1427297, 1427295, 1427293, 1427294, 1427292, 1427291, 1427290, 1427289, 1427288, 1427287, 1427285, 1427286, 1427281, 1427283, 1427282, 1427280, 1427277, 1427278, 1427276, 1427274, 1427275, 1427271, 1427273, 1427272, 1427270, 1427269, 1427268, 1427264, 1427266, 1427265, 1427261, 1427260, 1427262, 1427259, 1421992, 1421990, 1421991, 1421989, 1421987, 1421988, 1421986, 1421985, 1421983, 1421984, 1421980, 1421979, 1421974, 1421975, 1421976, 1421972, 1421973, 1421971, 1421967, 1421969, 1421966, 1421962, 1421965, 1421964, 1421961, 1421960, 1421959, 1421958, 1421957, 1421954, 1421956, 1421955, 1421952, 1421951, 1421953, 1421949, 1421948, 1421950, 1421944, 1421947, 1421946, 1421945, 1421943, 1421942, 1421940, 1421939, 1421938, 1421936, 1421937, 1421935, 1421933, 1421934, 1421932, 1421931, 1421930, 1421927, 1421929, 1421928, 1421926, 1421925, 1421924, 1421923, 1421922, 1421921, 1421920, 1421918, 1421919, 1418255, 1421917, 1418256, 1418254, 1418252, 1418253, 1418251, 83331, 1417031, 478434, 478433, 1417005, 1417029, 1417030, 1417027, 1417023, 1417018, 1417021, 1417016, 1417017, 1417015, 1417014, 1417012, 1417013, 1417010, 1417009, 1417008, 1408975, 1408974, 1408970, 1408971, 1408973, 1408969, 1408968, 1408965, 1408967, 1408963, 1408964, 1408959, 1408960, 1408962, 1408958, 1408956, 1408957, 1408955, 1408954, 1408953, 1408952, 1408950, 1408951, 1408949, 1408946, 1408948, 1408947, 1408945, 1408944, 1408939, 1408942, 1408941, 1408940, 1408938, 1408937, 1408934, 1408936, 1408935, 1408933, 1408932, 1408931, 1408928, 1408930, 1408929, 1408925, 1408926, 1408924, 1408923, 1408922, 1408919, 1408921, 1408920, 1408918, 652616, 1402602, 1402601, 1402600, 1402598, 1402599, 1402597, 1402596, 1402593, 1402595, 1402591, 1402592, 1402589, 1402588, 1402590, 1402586, 1402587, 1402585, 1402584, 1402583, 336982, 395095, 1354117, 1354115, 1354116, 1354114, 1354111, 1354112, 1354110, 1354109, 1354107, 1354108, 1354105, 1354106, 1354104, 1354103, 1354102, 1354101, 1354189, 1354121, 1354120, 1354119, 1354142, 1354135, 1354188, 1354191, 1354136, 1354133, 1354134, 1354131, 1354132, 1354130, 1354128, 1354129, 1354125, 1354127, 1354124, 1354126, 1354123, 1354122, 1354141, 1354140, 1354187, 1354139, 1354192, 1354138, 1354155, 1354137, 1354186, 1354183, 1354182, 1354154, 1354181, 1354180, 1354160, 1354179, 1354178, 1354158, 1354176, 1354177, 1354175, 1354152, 1354174, 1354153, 1354151, 1354149, 1354150, 1354173, 1354148, 1354172, 1354193, 1354147, 1354171, 1354146, 1354145, 1354144, 1354165, 1354166, 1354143, 1354162, 1354164, 1354161, 33894, 537209, 611302, 515615, 537210, 611303, 520140, 520141, 611304, 1448837, 1448838, 515617, 1448834, 1448836, 1448833, 1448830, 1448829, 1448828, 1448826, 1448825, 1448824, 1448823, 1448822, 1448821, 1448819, 1448818, 1448817, 1448816, 1448815, 1448814, 1448813, 1448812, 1448811, 1448810, 1448808, 1448807, 1448806, 1448805, 1448804, 1448803, 1448802, 1448801, 1448800, 1448799, 1448798, 1448797, 1448796, 1448795, 1448794, 1448792, 1448791, 1448790, 1448789, 1448788, 1448787, 1448786, 1448785, 1448784, 1448783, 1448781, 1448780, 1448779, 1448778, 1448776, 1448775, 1448774, 1448772, 1448771, 1448770, 1448769, 1448768, 1448767, 1448766, 1448765, 1448764, 1448763, 1448762, 1448761, 1448760, 1448759, 1448758, 1448756, 1448757, 1448755, 1448754, 1448753, 1448752, 1448751, 1448750, 1448748, 1448747, 1448746, 1448745, 1448744, 1448743, 1448742, 1448740, 1448739, 1448738, 1448737, 1448736, 1448735, 1448734, 1448733, 1448732, 1448731, 1448730, 1448729, 1448728, 1448726, 1448725, 1448724, 1448723, 1448722, 1448721, 1448720, 1448719, 1448718, 1448717, 1448716, 1448715, 1448713, 1448712, 1448711, 1448710, 1448709, 1448708, 1448707, 1448706, 1448705, 1448704, 1448703, 1448702, 1448700, 1448701, 1448699, 1448698, 1448696, 1448697, 1448694, 1448695, 1448693, 1448692, 1448690, 1448691, 1448689, 1448688, 1448687, 1448683, 1448686, 1448685, 1448682, 1448684, 1448679, 1448680, 1448681, 1448678, 1448676, 1448677, 1448675, 1448674, 1448671, 1448672, 1448673, 1448670, 1448667, 1448669, 1448666, 1448668, 1448665, 1448664, 1448662, 1448661, 1448663, 1448659, 1448660, 1448658, 1448656, 1448654, 1448657, 1448653, 1448651, 1448652, 1448650, 1448649, 1448647, 1448648, 1448645, 1448644, 1448646, 1448642, 1448640, 1448643, 1448641, 1448639, 1448637, 1448638, 1448634, 1448635, 1448636, 1448632, 1448628, 1448633, 1448629, 1448627, 1448626, 1448623, 1448625, 1448622, 1448624, 1448620, 1448621, 1448619, 1448615, 1448618, 1448617, 1448616, 1448613, 1448614, 1448612, 1448611, 1448610, 1448582, 1448585, 1448577, 1448584, 1448579, 1448576, 1448572, 1448574, 1448569, 1448571, 1448567, 1448570, 1448565, 1448568, 1448563, 1448562, 1448561, 1448560, 1448556, 1448555, 1448554, 1448552, 1448551, 1448550, 1448549, 1448548, 1448547, 1448545, 1448544, 1448546, 1448542, 1448540, 1448538, 1448536, 1448535, 1448533, 1448532, 1448531, 1448529, 1448526, 1448524, 1448521, 1448523, 1448522, 1448517, 1448514, 1448513, 1448512, 1448509, 1448507, 1448508, 1448505, 1448504, 1448501, 1448498, 1448502, 1448497, 1448496, 1448492, 1448491, 1448485, 1448484, 1448486, 1448483, 1448482, 1448480, 1448479, 1448481, 1448477, 1448476, 1448478, 1448475, 1448473, 1448474, 1448471, 1448472, 1448470, 1448468, 1448466, 1448469, 1448465, 1448463, 1448464, 1448461, 1448459, 1448462, 1448458, 1448460, 1448456, 1448455, 1448454, 1448453, 1448450, 1448452, 1448447, 1448449, 1448448, 1448446, 1448445, 1448443, 1448442, 1448439, 1448440, 1448437, 1448434, 1448435, 1448432, 1448431, 1448433, 1448430, 1448427, 1448428, 1448426, 1448421, 1448411, 1448417, 1448414, 1448412, 1448409, 1448410, 1448407, 1448404, 1448406, 1448405, 1448403, 1448402, 1448401, 1448399, 1448400, 1448398, 1448397, 1448395, 1448396, 1448394, 1448393, 1448392, 1447527, 1448390, 1447526, 1447525, 1447524, 1447523, 1447522, 1447521, 1447520, 1447519, 1447517, 1447516, 1447515, 1447514, 1447513, 1447511, 1447510, 1447512, 1447509, 1447508, 1447504, 1447507, 1447502, 1447500, 1447501, 1447498, 1447497, 1447496, 1447495, 1447493, 1447494, 1447492, 1447491, 1447490, 1447489, 1447487, 1447486, 1447485, 1447484, 1447483, 1447480, 1447479, 1447476, 1447475, 1447474, 1447472, 1447471, 1447470, 1447469, 1447468, 1447467, 1447466, 1447465, 1447464, 1447463, 1447462, 1447461, 1447460, 1447458, 1447459, 1447457, 1447455, 1447454, 1447453, 1447452, 1447451, 1447449, 1447447, 1447446, 1447444, 1447443, 1447442, 1447441, 1447440, 1447439, 1447438, 1447437, 1447434, 1447433, 1447432, 1438822, 1438826, 1438827, 1438829, 1438823, 1438833, 1438828, 1438835, 1438837, 1438838, 1438842, 1438874, 1438844, 1438845, 1438868, 1438870, 1438846, 1438851, 1438848, 1438849, 1438852, 1438858, 1438872, 1438859, 1438843, 1438860, 1438865, 1448606, 1448598, 1448580, 1448575, 1448566, 1448573, 1448564, 1448539, 1448534, 1448527, 1448516, 1448490, 1438825, 1448467, 1438856, 1438824, 1438853, 1438864, 1438863, 1438866, 1423429, 1448777, 1448727, 1448631, 1448630, 1421970, 515616, 1447478, 1447477, 1447456, 1447448, 1447436, 1447435, 1427253, 1427214, 1438884, 1427231, 1427202, 1438840, 1438890, 1417028, 1417026, 1417020, 1417019, 1417011, 1408943, 1408916, 1408927, 1402478, 1324246, 1458472, 998092, 443150, 1010836, 1010835, 1010834, 1441927, 1441925, 1441926, 1384084, 1389959, 1245275, 1245787, 555461, 1306414, 443149, 1310115, 1306400, 478435, 1091501, 1091500, 717522, 707235, 659019, 911237, 675523, 675520, 675519, 675518, 675517, 675516, 675515, 675514, 675513, 419947, 115862, 1445606, 1427516, 1138877, 1205675, 1097669, 1078763, 413996, 561275, 410289 Mycobacterium bovis AF2122/97, Mycobacterium tuberculosis H37Rv, Mycobacterium bovis BCG, Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium tuberculosis 18b, Mycobacterium tuberculosis H37RvSiena, Mycobacterium tuberculosis str. Beijing/DS6701, Mycobacterium tuberculosis KT-0045, Mycobacterium tuberculosis TKK_04_0124, Mycobacterium tuberculosis KT-0023, Mycobacterium tuberculosis KT-0079, Mycobacterium tuberculosis TRUG0119, Mycobacterium tuberculosis KT-0107, Mycobacterium tuberculosis MD17890, Mycobacterium tuberculosis XTB13-201, Mycobacterium tuberculosis MD17646, Mycobacterium tuberculosis MD17901, Mycobacterium tuberculosis MD15958, Mycobacterium tuberculosis MD15751, Mycobacterium tuberculosis MD15774, Mycobacterium tuberculosis MD13744, Mycobacterium tuberculosis MD14839, Mycobacterium tuberculosis MD14825, Mycobacterium tuberculosis MAL010117, Mycobacterium tuberculosis MAL010124, Mycobacterium tuberculosis MAL020102, Mycobacterium tuberculosis MAL020205, Mycobacterium tuberculosis TB_RSA52, Mycobacterium tuberculosis M1759, Mycobacterium tuberculosis M1307, Mycobacterium tuberculosis M2084, Mycobacterium tuberculosis M2193, Mycobacterium tuberculosis H1964, Mycobacterium tuberculosis H2375, Mycobacterium tuberculosis BTB04-120, Mycobacterium tuberculosis M2898, Mycobacterium tuberculosis BTB07-234, Mycobacterium tuberculosis BTB07-314, Mycobacterium tuberculosis BTB07-327, Mycobacterium tuberculosis BTB08-395, Mycobacterium tuberculosis BTB10-305, Mycobacterium tuberculosis BTB13-001, Mycobacterium tuberculosis 2231BH, Mycobacterium tuberculosis 2097HD, Mycobacterium tuberculosis 2995AB, Mycobacterium tuberculosis 2092HD, Mycobacterium tuberculosis 2542MS, Mycobacterium tuberculosis TKK_03_0102, Mycobacterium tuberculosis TKK_05MA_0055, Mycobacterium tuberculosis TKK_05SA_0024, Mycobacterium tuberculosis NRITLD28, Mycobacterium tuberculosis MD18115, Mycobacterium tuberculosis NRITLD18, Mycobacterium tuberculosis 2104HD, Mycobacterium tuberculosis K, Mycobacterium tuberculosis XTB13-179, Mycobacterium tuberculosis XTB13-178, Mycobacterium tuberculosis XTB13-177, Mycobacterium tuberculosis XTB13-176, Mycobacterium tuberculosis XTB13-175, Mycobacterium tuberculosis XTB13-172, Mycobacterium tuberculosis XTB13-169, Mycobacterium tuberculosis XTB13-168, Mycobacterium tuberculosis XTB13-167, Mycobacterium tuberculosis XTB13-165, Mycobacterium tuberculosis XTB13-161, Mycobacterium tuberculosis XTB13-162, Mycobacterium tuberculosis XTB13-159, Mycobacterium tuberculosis XTB13-158, Mycobacterium tuberculosis XTB13-156, Mycobacterium tuberculosis XTB13-154, Mycobacterium tuberculosis XTB13-155, Mycobacterium tuberculosis XTB13-152, Mycobacterium tuberculosis XTB13-153, Mycobacterium tuberculosis XTB13-150, Mycobacterium tuberculosis XTB13-147, Mycobacterium tuberculosis XTB13-146, Mycobacterium tuberculosis XTB13-144, Mycobacterium tuberculosis XTB13-145, Mycobacterium tuberculosis XTB13-141, Mycobacterium tuberculosis XTB13-143, Mycobacterium tuberculosis XTB13-138, Mycobacterium tuberculosis XTB13-140, Mycobacterium tuberculosis XTB13-137, Mycobacterium tuberculosis XTB13-136, Mycobacterium tuberculosis XTB13-134, Mycobacterium tuberculosis XTB13-135, Mycobacterium tuberculosis XTB13-132, Mycobacterium tuberculosis XTB13-133, Mycobacterium tuberculosis XTB13-131, Mycobacterium tuberculosis XTB13-128, Mycobacterium tuberculosis XTB13-127, Mycobacterium tuberculosis XTB13-126, Mycobacterium tuberculosis XTB13-125, Mycobacterium tuberculosis XTB13-124, Mycobacterium tuberculosis XTB13-121, Mycobacterium tuberculosis XTB13-122, Mycobacterium tuberculosis XTB13-120, Mycobacterium tuberculosis XTB13-119, Mycobacterium tuberculosis XTB13-117, Mycobacterium tuberculosis XTB13-115, Mycobacterium tuberculosis XTB13-116, Mycobacterium tuberculosis XTB13-114, Mycobacterium tuberculosis XTB13-113, Mycobacterium tuberculosis XTB13-111, Mycobacterium tuberculosis XTB13-112, Mycobacterium tuberculosis XTB13-107, Mycobacterium tuberculosis XTB13-108, Mycobacterium tuberculosis XTB13-105, Mycobacterium tuberculosis XTB13-104, Mycobacterium tuberculosis XTB13-103, Mycobacterium tuberculosis XTB13-100, Mycobacterium tuberculosis XTB13-102, Mycobacterium tuberculosis XTB13-098, Mycobacterium tuberculosis XTB13-097, Mycobacterium tuberculosis XTB13-096, Mycobacterium tuberculosis XTB13-095, Mycobacterium tuberculosis XTB13-094, Mycobacterium tuberculosis XTB13-093, Mycobacterium tuberculosis XTB13-092, Mycobacterium tuberculosis XTB13-091, Mycobacterium tuberculosis XTB13-089, Mycobacterium tuberculosis XTB13-088, Mycobacterium tuberculosis XTB13-084, Mycobacterium tuberculosis XTB13-086, Mycobacterium tuberculosis XTB13-083, Mycobacterium tuberculosis BTB13-276, Mycobacterium tuberculosis XTB13-082, Mycobacterium tuberculosis XTB13-081, Mycobacterium tuberculosis BTB13-222, Mycobacterium tuberculosis BTB13-206, Mycobacterium tuberculosis BTB13-128, Mycobacterium tuberculosis BTB13-156, Mycobacterium tuberculosis BTB13-127, Mycobacterium tuberculosis BTB13-089, Mycobacterium tuberculosis BTB13-063, Mycobacterium tuberculosis BTB12-449, Mycobacterium tuberculosis BTB12-384, Mycobacterium tuberculosis BTB12-400, Mycobacterium tuberculosis BTB12-315, Mycobacterium tuberculosis BTB12-314, Mycobacterium tuberculosis BTB12-313, Mycobacterium tuberculosis BTB12-305, Mycobacterium tuberculosis BTB12-304, Mycobacterium tuberculosis BTB12-294, Mycobacterium tuberculosis BTB12-211, Mycobacterium tuberculosis BTB12-206, Mycobacterium tuberculosis BTB12-162, Mycobacterium tuberculosis BTB12-094, Mycobacterium tuberculosis BTB12-054, Mycobacterium tuberculosis BTB12-046, Mycobacterium tuberculosis BTB12-002, Mycobacterium tuberculosis BTB12-001, Mycobacterium tuberculosis BTB11-371, Mycobacterium tuberculosis BTB11-343, Mycobacterium tuberculosis BTB11-300, Mycobacterium tuberculosis BTB11-289, Mycobacterium tuberculosis BTB11-250, Mycobacterium tuberculosis BTB11-214, Mycobacterium tuberculosis BTB11-236, Mycobacterium tuberculosis BTB11-210, Mycobacterium tuberculosis BTB11-207, Mycobacterium tuberculosis BTB11-195, Mycobacterium tuberculosis BTB11-192, Mycobacterium tuberculosis BTB11-160, Mycobacterium tuberculosis BTB11-139, Mycobacterium tuberculosis BTB11-112, Mycobacterium tuberculosis BTB11-133, Mycobacterium tuberculosis BTB11-047, Mycobacterium tuberculosis BTB11-001, Mycobacterium tuberculosis BTB11-027, Mycobacterium tuberculosis BTB10-472, Mycobacterium tuberculosis BTB10-487, Mycobacterium tuberculosis BTB10-426, Mycobacterium tuberculosis BTB10-406, Mycobacterium tuberculosis BTB10-422, Mycobacterium tuberculosis BTB10-367, Mycobacterium tuberculosis BTB10-357, Mycobacterium tuberculosis BTB10-295, Mycobacterium tuberculosis BTB10-277, Mycobacterium tuberculosis BTB10-257, Mycobacterium tuberculosis BTB10-142, Mycobacterium tuberculosis BTB10-120, Mycobacterium tuberculosis BTB10-097, Mycobacterium tuberculosis BTB10-005, Mycobacterium tuberculosis BTB09-554, Mycobacterium tuberculosis BTB10-001, Mycobacterium tuberculosis BTB09-553, Mycobacterium tuberculosis BTB09-485, Mycobacterium tuberculosis BTB09-453, Mycobacterium tuberculosis BTB09-382, Mycobacterium tuberculosis BTB09-230, Mycobacterium tuberculosis BTB09-184, Mycobacterium tuberculosis BTB09-157, Mycobacterium tuberculosis BTB09-151, Mycobacterium tuberculosis BTB09-091, Mycobacterium tuberculosis BTB09-086, Mycobacterium tuberculosis BTB09-085, Mycobacterium tuberculosis BTB09-058, Mycobacterium tuberculosis BTB09-001, Mycobacterium tuberculosis BTB09-036, Mycobacterium tuberculosis BTB08-394, Mycobacterium tuberculosis BTB08-362, Mycobacterium tuberculosis BTB08-356, Mycobacterium tuberculosis BTB08-309, Mycobacterium tuberculosis BTB08-288, Mycobacterium tuberculosis BTB08-221, Mycobacterium tuberculosis BTB08-283, Mycobacterium tuberculosis BTB08-183, Mycobacterium tuberculosis BTB08-148, Mycobacterium tuberculosis BTB08-093, Mycobacterium tuberculosis BTB08-072, Mycobacterium tuberculosis BTB08-022, Mycobacterium tuberculosis BTB08-043, Mycobacterium tuberculosis BTB08-014, Mycobacterium tuberculosis BTB08-001, Mycobacterium tuberculosis BTB07-354, Mycobacterium tuberculosis BTB07-325, Mycobacterium tuberculosis BTB07-324, Mycobacterium tuberculosis BTB07-323, Mycobacterium tuberculosis BTB07-300, Mycobacterium tuberculosis BTB07-299, Mycobacterium tuberculosis BTB07-275, Mycobacterium tuberculosis BTB07-283, Mycobacterium tuberculosis BTB07-254, Mycobacterium tuberculosis BTB07-261, Mycobacterium tuberculosis BTB07-243, Mycobacterium tuberculosis BTB07-246, Mycobacterium tuberculosis BTB07-206, Mycobacterium tuberculosis BTB03-144, Mycobacterium tuberculosis BTB07-170, Mycobacterium tuberculosis BTB07-126, Mycobacterium tuberculosis BTB07-123, Mycobacterium tuberculosis BTB07-034, Mycobacterium tuberculosis BTB07-070, Mycobacterium tuberculosis BTB07-001, Mycobacterium tuberculosis BTB06-494, Mycobacterium tuberculosis BTB06-467, Mycobacterium tuberculosis BTB06-340, Mycobacterium tuberculosis BTB06-001, Mycobacterium tuberculosis BTB05-660, Mycobacterium tuberculosis BTB05-650, Mycobacterium tuberculosis BTB03-143, Mycobacterium tuberculosis BTB05-371, Mycobacterium tuberculosis BTB05-348, Mycobacterium tuberculosis BTB05-285, Mycobacterium tuberculosis BTB05-013, Mycobacterium tuberculosis BTB05-001, Mycobacterium tuberculosis BTB04-452, Mycobacterium tuberculosis BTB04-416, Mycobacterium tuberculosis BTB04-172, Mycobacterium tuberculosis BTB04-388, Mycobacterium tuberculosis BTB04-128, Mycobacterium tuberculosis BTB04-158, Mycobacterium tuberculosis BTB03-142, Mycobacterium tuberculosis BTB04-097, Mycobacterium tuberculosis BTB04-001, Mycobacterium tuberculosis BTB04-011, Mycobacterium tuberculosis BTB03-169, Mycobacterium tuberculosis BTB03-168, Mycobacterium tuberculosis BTB03-108, Mycobacterium tuberculosis BTB05-481, Mycobacterium tuberculosis BTB03-012, Mycobacterium tuberculosis TB_RSA200, Mycobacterium tuberculosis TB_RSA196, Mycobacterium tuberculosis TB_RSA199, Mycobacterium tuberculosis TB_RSA197, Mycobacterium tuberculosis TB_RSA194, Mycobacterium tuberculosis TB_RSA195, Mycobacterium tuberculosis TB_RSA193, Mycobacterium tuberculosis TB_RSA192, Mycobacterium tuberculosis TB_RSA191, Mycobacterium tuberculosis TB_RSA190, Mycobacterium tuberculosis TB_RSA184, Mycobacterium tuberculosis TB_RSA189, Mycobacterium tuberculosis TB_RSA181, Mycobacterium tuberculosis TB_RSA182, Mycobacterium tuberculosis TB_RSA180, Mycobacterium tuberculosis TB_RSA178, Mycobacterium tuberculosis TB_RSA179, Mycobacterium tuberculosis TB_RSA176, Mycobacterium tuberculosis TB_RSA177, Mycobacterium tuberculosis TB_RSA175, Mycobacterium tuberculosis TB_RSA174, Mycobacterium tuberculosis TB_RSA173, Mycobacterium tuberculosis TB_RSA172, Mycobacterium tuberculosis TB_RSA171, Mycobacterium tuberculosis TB_RSA169, Mycobacterium tuberculosis TB_RSA170, Mycobacterium tuberculosis TB_RSA168, Mycobacterium tuberculosis TB_RSA167, Mycobacterium tuberculosis TB_RSA166, Mycobacterium tuberculosis TB_RSA165, Mycobacterium tuberculosis TB_RSA164, Mycobacterium tuberculosis TB_RSA163, Mycobacterium tuberculosis TB_RSA162, Mycobacterium tuberculosis TB_RSA160, Mycobacterium tuberculosis TB_RSA161, Mycobacterium tuberculosis TB_RSA159, Mycobacterium tuberculosis TB_RSA158, Mycobacterium tuberculosis TB_RSA157, Mycobacterium tuberculosis TB_RSA156, Mycobacterium tuberculosis TB_RSA155, Mycobacterium tuberculosis TB_RSA154, Mycobacterium tuberculosis TB_RSA153, Mycobacterium tuberculosis TB_RSA152, Mycobacterium tuberculosis TB_RSA151, Mycobacterium tuberculosis TB_RSA150, Mycobacterium tuberculosis TB_RSA149, Mycobacterium tuberculosis TB_RSA148, Mycobacterium tuberculosis TB_RSA147, Mycobacterium tuberculosis TB_RSA144, Mycobacterium tuberculosis TB_RSA143, Mycobacterium tuberculosis TB_RSA141, Mycobacterium tuberculosis TB_RSA142, Mycobacterium tuberculosis TB_RSA139, Mycobacterium tuberculosis TB_RSA140, Mycobacterium tuberculosis TB_RSA138, Mycobacterium tuberculosis TB_RSA137, Mycobacterium tuberculosis TB_RSA136, Mycobacterium tuberculosis TB_RSA135, Mycobacterium tuberculosis TB_RSA134, Mycobacterium tuberculosis TB_RSA133, Mycobacterium tuberculosis TB_RSA131, Mycobacterium tuberculosis TB_RSA132, Mycobacterium tuberculosis TB_RSA130, Mycobacterium tuberculosis TB_RSA129, Mycobacterium tuberculosis TB_RSA128, Mycobacterium tuberculosis TB_RSA126, Mycobacterium tuberculosis TB_RSA127, Mycobacterium tuberculosis TB_RSA125, Mycobacterium tuberculosis TB_RSA120, Mycobacterium tuberculosis TB_RSA119, Mycobacterium tuberculosis TB_RSA118, Mycobacterium tuberculosis TB_RSA117, Mycobacterium tuberculosis TB_RSA113, Mycobacterium tuberculosis TB_RSA109, Mycobacterium tuberculosis TB_RSA108, Mycobacterium tuberculosis TB_RSA105, Mycobacterium tuberculosis TB_RSA104, Mycobacterium tuberculosis TB_RSA101, Mycobacterium tuberculosis TB_RSA100, Mycobacterium tuberculosis TB_RSA99, Mycobacterium tuberculosis TB_RSA98, Mycobacterium tuberculosis TB_RSA97, Mycobacterium tuberculosis TB_RSA96, Mycobacterium tuberculosis TB_RSA95, Mycobacterium tuberculosis TB_RSA94, Mycobacterium tuberculosis TB_RSA92, Mycobacterium tuberculosis TB_RSA93, Mycobacterium tuberculosis TB_RSA91, Mycobacterium tuberculosis TB_RSA90, Mycobacterium tuberculosis TB_RSA88, Mycobacterium tuberculosis TB_RSA89, Mycobacterium tuberculosis TB_RSA87, Mycobacterium tuberculosis TB_RSA86, Mycobacterium tuberculosis TB_RSA85, Mycobacterium tuberculosis TB_RSA84, Mycobacterium tuberculosis TB_RSA82, Mycobacterium tuberculosis TB_RSA81, Mycobacterium tuberculosis TB_RSA80, Mycobacterium tuberculosis TB_RSA79, Mycobacterium tuberculosis TRUG0024, Mycobacterium tuberculosis TRUG0022, Mycobacterium tuberculosis TRUG0020, Mycobacterium tuberculosis TRUG0016, Mycobacterium tuberculosis TRUG0015, Mycobacterium tuberculosis TRUG0009, Mycobacterium tuberculosis TRUG0004, Mycobacterium tuberculosis TRUG0002, Mycobacterium tuberculosis TRUG0003, Mycobacterium tuberculosis TRUG0001, Mycobacterium tuberculosis UG-D, Mycobacterium tuberculosis UG-C, Mycobacterium tuberculosis SK-C, Mycobacterium tuberculosis SK-E, Mycobacterium tuberculosis KT-0110, Mycobacterium tuberculosis KT-0108, Mycobacterium tuberculosis KT-0109, Mycobacterium tuberculosis KT-0106, Mycobacterium tuberculosis KT-0104, Mycobacterium tuberculosis KT-0100, Mycobacterium tuberculosis KT-0102, Mycobacterium tuberculosis KT-0098, Mycobacterium tuberculosis KT-0099, Mycobacterium tuberculosis KT-0094, Mycobacterium tuberculosis KT-0096, Mycobacterium tuberculosis KT-0092, Mycobacterium tuberculosis KT-0091, Mycobacterium tuberculosis KT-0089, Mycobacterium tuberculosis KT-0085, Mycobacterium tuberculosis KT-0084, Mycobacterium tuberculosis KT-0083, Mycobacterium tuberculosis KT-0080, Mycobacterium tuberculosis KT-0078, Mycobacterium tuberculosis KT-0075, Mycobacterium tuberculosis KT-0077, Mycobacterium tuberculosis KT-0072, Mycobacterium tuberculosis KT-0071, Mycobacterium tuberculosis KT-0070, Mycobacterium tuberculosis KT-0064, Mycobacterium tuberculosis KT-0063, Mycobacterium tuberculosis KT-0058, Mycobacterium tuberculosis KT-0056, Mycobacterium tuberculosis KT-0057, Mycobacterium tuberculosis KT-0053, Mycobacterium tuberculosis KT-0051, Mycobacterium tuberculosis KT-0048, Mycobacterium tuberculosis KT-0047, Mycobacterium tuberculosis KT-0043, Mycobacterium tuberculosis KT-0039, Mycobacterium tuberculosis KT-0041, Mycobacterium tuberculosis KT-0035, Mycobacterium tuberculosis KT-0028, Mycobacterium tuberculosis KT-0027, Mycobacterium tuberculosis KT-0026, Mycobacterium tuberculosis KT-0022, Mycobacterium tuberculosis KT-0024, Mycobacterium tuberculosis KT-0019, Mycobacterium tuberculosis KT-0017, Mycobacterium tuberculosis KT-0015, Mycobacterium tuberculosis KT-0016, Mycobacterium tuberculosis KT-0014, Mycobacterium tuberculosis KT-0011, Mycobacterium tuberculosis KT-0007, Mycobacterium tuberculosis KT-0008, Mycobacterium tuberculosis KT-0006, Mycobacterium tuberculosis KT-0003, Mycobacterium tuberculosis KT-0001, Mycobacterium tuberculosis KT-0002, Mycobacterium tuberculosis TKK_04_0033, Mycobacterium tuberculosis TKK_04_0029, Mycobacterium tuberculosis TKK_04_0030, Mycobacterium tuberculosis TKK_04_0037, Mycobacterium tuberculosis TKK_04_0044, Mycobacterium tuberculosis TKK_04_0040, Mycobacterium tuberculosis TKK_04_0039, Mycobacterium tuberculosis TKK_04_0038, Mycobacterium tuberculosis TKK_04_0020, Mycobacterium tuberculosis TKK_04_0034, Mycobacterium tuberculosis TKK_04_0013, Mycobacterium tuberculosis TKK_04_0005, Mycobacterium tuberculosis TKK_04_0047, Mycobacterium tuberculosis TKK_04_0048, Mycobacterium tuberculosis TKK_04_0043, Mycobacterium tuberculosis TKK_04_0023, Mycobacterium tuberculosis TKK_04_0024, Mycobacterium tuberculosis TKK_04_0022, Mycobacterium tuberculosis TKK_04_0019, Mycobacterium tuberculosis TKK_04_0018, Mycobacterium tuberculosis TKK_04_0017, Mycobacterium tuberculosis TKK_04_0015, Mycobacterium tuberculosis TKK_04_0014, Mycobacterium tuberculosis TKK_04_0003, Mycobacterium tuberculosis TKK_04_0006, Mycobacterium tuberculosis TKK_04_0002, Mycobacterium tuberculosis TKK_04_0001, Mycobacterium tuberculosis TKK_03_0082, Mycobacterium tuberculosis TKK_03_0081, Mycobacterium tuberculosis TKK_03_0078, Mycobacterium tuberculosis TKK_03_0045, Mycobacterium tuberculosis TKK_03_0036, Mycobacterium tuberculosis TKK_03_0043, Mycobacterium tuberculosis TKK_03_0034, Mycobacterium tuberculosis TKK_03_0033, Mycobacterium tuberculosis TKK_03_0031, Mycobacterium tuberculosis TKK_03_0029, Mycobacterium tuberculosis TKK_03_0030, Mycobacterium tuberculosis TKK_03_0027, Mycobacterium tuberculosis TKK_03_0026, Mycobacterium tuberculosis TKK_03_0022, Mycobacterium tuberculosis TKK_03_0025, Mycobacterium tuberculosis TKK_03_0020, Mycobacterium tuberculosis TKK_03_0018, Mycobacterium tuberculosis TKK_02_0077, Mycobacterium tuberculosis TKK_02_0073, Mycobacterium tuberculosis TKK_02_0070, Mycobacterium tuberculosis TKK_02_0071, Mycobacterium tuberculosis TKK_02_0068, Mycobacterium tuberculosis TKK_02_0069, Mycobacterium tuberculosis TKK_02_0063, Mycobacterium tuberculosis TKK_02_0062, Mycobacterium tuberculosis TKK_02_0061, Mycobacterium tuberculosis TKK_02_0046, Mycobacterium tuberculosis TKK_02_0052, Mycobacterium tuberculosis TKK_02_0045, Mycobacterium tuberculosis TKK_02_0039, Mycobacterium tuberculosis TKK_02_0038, Mycobacterium tuberculosis TKK_02_0036, Mycobacterium tuberculosis TKK_02_0034, Mycobacterium tuberculosis TKK_02_0027, Mycobacterium tuberculosis TKK_02_0033, Mycobacterium tuberculosis TKK_02_0025, Mycobacterium tuberculosis TKK_02_0022, Mycobacterium tuberculosis TKK_02_0021, Mycobacterium tuberculosis TKK_02_0019, Mycobacterium tuberculosis TKK_02_0020, Mycobacterium tuberculosis TKK_02_0018, Mycobacterium tuberculosis TKK_02_0017, Mycobacterium tuberculosis TKK_02_0016, Mycobacterium tuberculosis TKK_02_0015, Mycobacterium tuberculosis TKK_02_0014, Mycobacterium tuberculosis TKK_02_0013, Mycobacterium tuberculosis TKK_02_0012, Mycobacterium tuberculosis TKK_02_0003, Mycobacterium tuberculosis TKK_02_0006, Mycobacterium tuberculosis TKK_02_0002, Mycobacterium tuberculosis TKK_02_0001, Mycobacterium tuberculosis BTB10-258, Mycobacterium tuberculosis BTB10-308, Mycobacterium tuberculosis BTB10-253, Mycobacterium tuberculosis BTB10-092, Mycobacterium tuberculosis BTB09-377, Mycobacterium tuberculosis BTB09-565, Mycobacterium tuberculosis TKK-01-0094, Mycobacterium tuberculosis TKK-01-0092, Mycobacterium tuberculosis TKK-01-0093, Mycobacterium tuberculosis TKK-01-0091, Mycobacterium tuberculosis TKK-01-0090, Mycobacterium tuberculosis TKK-01-0088, Mycobacterium tuberculosis TKK-01-0089, Mycobacterium tuberculosis TKK-01-0087, Mycobacterium tuberculosis TKK-01-0085, Mycobacterium tuberculosis TKK-01-0086, Mycobacterium tuberculosis TKK-01-0084, Mycobacterium tuberculosis TKK-01-0083, Mycobacterium tuberculosis TKK-01-0081, Mycobacterium tuberculosis TKK-01-0082, Mycobacterium tuberculosis TKK-01-0078, Mycobacterium tuberculosis TKK-01-0079, Mycobacterium tuberculosis TKK-01-0075, Mycobacterium tuberculosis TKK-01-0077, Mycobacterium tuberculosis TKK-01-0076, Mycobacterium tuberculosis TKK-01-0074, Mycobacterium tuberculosis TKK-01-0073, Mycobacterium tuberculosis TKK-01-0071, Mycobacterium tuberculosis TKK-01-0070, Mycobacterium tuberculosis TKK-01-0068, Mycobacterium tuberculosis TKK-01-0067, Mycobacterium tuberculosis TKK-01-0066, Mycobacterium tuberculosis TKK-01-0065, Mycobacterium tuberculosis TKK-01-0063, Mycobacterium tuberculosis TKK-01-0062, Mycobacterium tuberculosis TKK-01-0060, Mycobacterium tuberculosis TKK-01-0058, Mycobacterium tuberculosis TKK-01-0056, Mycobacterium tuberculosis TKK-01-0055, Mycobacterium tuberculosis TKK-01-0054, Mycobacterium tuberculosis TKK-01-0053, Mycobacterium tuberculosis TKK-01-0052, Mycobacterium tuberculosis TKK-01-0049, Mycobacterium tuberculosis TKK-01-0050, Mycobacterium tuberculosis TKK-01-0047, Mycobacterium tuberculosis TKK-01-0048, Mycobacterium tuberculosis TKK-01-0046, Mycobacterium tuberculosis TKK-01-0044, Mycobacterium tuberculosis TKK-01-0045, Mycobacterium tuberculosis TKK-01-0043, Mycobacterium tuberculosis TKK-01-0040, Mycobacterium tuberculosis TKK-01-0041, Mycobacterium tuberculosis TKK-01-0038, Mycobacterium tuberculosis TKK-01-0039, Mycobacterium tuberculosis TKK-01-0037, Mycobacterium tuberculosis TKK-01-0034, Mycobacterium tuberculosis TKK-01-0035, Mycobacterium tuberculosis TKK-01-0033, Mycobacterium tuberculosis TKK-01-0030, Mycobacterium tuberculosis TKK-01-0031, Mycobacterium tuberculosis TKK-01-0029, Mycobacterium tuberculosis TKK-01-0027, Mycobacterium tuberculosis TKK-01-0028, Mycobacterium tuberculosis TKK-01-0024, Mycobacterium tuberculosis TKK-01-0025, Mycobacterium tuberculosis TKK-01-0022, Mycobacterium tuberculosis TKK-01-0019, Mycobacterium tuberculosis TKK-01-0018, Mycobacterium tuberculosis TKK-01-0016, Mycobacterium tuberculosis TKK-01-0015, Mycobacterium tuberculosis TKK-01-0014, Mycobacterium tuberculosis TKK-01-0013, Mycobacterium tuberculosis TKK-01-0010, Mycobacterium tuberculosis TKK-01-0012, Mycobacterium tuberculosis TKK-01-0011, Mycobacterium tuberculosis TKK-01-0007, Mycobacterium tuberculosis TKK-01-0009, Mycobacterium tuberculosis TKK-01-0005, Mycobacterium tuberculosis TKK-01-0006, Mycobacterium tuberculosis TKK-01-0003, Mycobacterium tuberculosis TKK-01-0002, Mycobacterium tuberculosis TKK-01-0004, Mycobacterium tuberculosis TKK-01-0001, Mycobacterium tuberculosis OFXR-16, Mycobacterium tuberculosis OFXR-15, Mycobacterium tuberculosis OFXR-14, Mycobacterium tuberculosis OFXR-13, Mycobacterium tuberculosis OFXR-12, Mycobacterium tuberculosis OFXR-7, Mycobacterium tuberculosis OFXR-10, Mycobacterium tuberculosis OFXR-11, Mycobacterium tuberculosis OFXR-5, Mycobacterium tuberculosis OFXR-4, Mycobacterium tuberculosis OFXR-3, Mycobacterium tuberculosis OFXR-2, Mycobacterium tuberculosis TBR80, Mycobacterium tuberculosis TBR76, Mycobacterium tuberculosis TBR75, Mycobacterium tuberculosis TBR79, Mycobacterium tuberculosis TBR65, Mycobacterium tuberculosis TBR59, Mycobacterium tuberculosis TBR60, Mycobacterium tuberculosis TBR58, Mycobacterium tuberculosis TBR57, Mycobacterium tuberculosis TBR55, Mycobacterium tuberculosis TBR56, Mycobacterium tuberculosis TBR53, Mycobacterium tuberculosis TBR50, Mycobacterium tuberculosis TBR51, Mycobacterium tuberculosis TBR47, Mycobacterium tuberculosis TBR49, Mycobacterium tuberculosis TBR48, Mycobacterium tuberculosis TBR43, Mycobacterium tuberculosis TBR44, Mycobacterium tuberculosis TBR42, Mycobacterium tuberculosis TBR41, Mycobacterium tuberculosis TBR37, Mycobacterium tuberculosis TBR35, Mycobacterium tuberculosis TBR40, Mycobacterium tuberculosis TBR31, Mycobacterium tuberculosis TBR30, Mycobacterium tuberculosis TBR29, Mycobacterium tuberculosis TBR28, Mycobacterium tuberculosis TBR26, Mycobacterium tuberculosis TBR24, Mycobacterium tuberculosis TBR10, Mycobacterium tuberculosis TBR11, Mycobacterium tuberculosis TBR23, Mycobacterium tuberculosis TBR8, Mycobacterium tuberculosis TBR9, Mycobacterium tuberculosis TBR5, Mycobacterium tuberculosis TBR7, Mycobacterium tuberculosis TKK-01-0072, Mycobacterium tuberculosis TKK-01-0080, Mycobacterium tuberculosis TBR4, Mycobacterium tuberculosis TKK-01-0069, Mycobacterium tuberculosis TKK-01-0023, Mycobacterium tuberculosis TKK-01-0026, Mycobacterium tuberculosis TKK-01-0032, Mycobacterium tuberculosis TKK-01-0021, Mycobacterium tuberculosis TKK-01-0008, Mycobacterium tuberculosis NRITLD37, Mycobacterium tuberculosis TKK-01-0017, Mycobacterium tuberculosis NRITLD38, Mycobacterium tuberculosis NRITLD34, Mycobacterium tuberculosis NRITLD21, Mycobacterium tuberculosis NRITLD33, Mycobacterium tuberculosis NRITLD31, Mycobacterium tuberculosis NRITLD20, Mycobacterium tuberculosis NRITLD19, Mycobacterium tuberculosis NRITLD17, Mycobacterium tuberculosis NRITLD12, Mycobacterium tuberculosis NRITLD16, Mycobacterium tuberculosis NRITLD15, Mycobacterium tuberculosis NRITLD13, Mycobacterium tuberculosis NRITLD14, Mycobacterium tuberculosis NRITLD11, Mycobacterium tuberculosis NRITLD09, Mycobacterium tuberculosis NRITLD10, Mycobacterium tuberculosis NRITLD60, Mycobacterium tuberculosis NRITLD59, Mycobacterium tuberculosis NRITLD56, Mycobacterium tuberculosis NRITLD57, Mycobacterium tuberculosis NRITLD54, Mycobacterium tuberculosis NRITLD55, Mycobacterium tuberculosis NRITLD53, Mycobacterium tuberculosis NRITLD51, Mycobacterium tuberculosis NRITLD50, Mycobacterium tuberculosis NRITLD44, Mycobacterium tuberculosis NRITLD49, Mycobacterium tuberculosis NRITLD45, Mycobacterium tuberculosis NRITLD47, Mycobacterium tuberculosis TKK_04_0159, Mycobacterium tuberculosis TKK_04_0104, Mycobacterium tuberculosis TKK_04_0155, Mycobacterium tuberculosis TKK_04_0158, Mycobacterium tuberculosis TKK_04_0153, Mycobacterium tuberculosis TKK_04_0150, Mycobacterium tuberculosis TKK_04_0149, Mycobacterium tuberculosis TKK_04_0148, Mycobacterium tuberculosis TKK_04_0145, Mycobacterium tuberculosis TKK_04_0140, Mycobacterium tuberculosis TKK_04_0139, Mycobacterium tuberculosis TKK_04_0136, Mycobacterium tuberculosis TKK_04_0134, Mycobacterium tuberculosis TKK_04_0137, Mycobacterium tuberculosis TKK_04_0131, Mycobacterium tuberculosis TKK_04_0132, Mycobacterium tuberculosis 3280CJ, Mycobacterium tuberculosis TKK_04_0130, Mycobacterium tuberculosis TKK_04_0126, Mycobacterium tuberculosis TKK_04_0129, Mycobacterium tuberculosis 2233BH, Mycobacterium tuberculosis TKK_04_0125, Mycobacterium tuberculosis 2489, Mycobacterium tuberculosis 6273, Mycobacterium tuberculosis 9956, Mycobacterium tuberculosis 6638, Mycobacterium tuberculosis 10060, Mycobacterium tuberculosis 10217, Mycobacterium tuberculosis 12974, Mycobacterium tuberculosis 16955, Mycobacterium tuberculosis 8442, Mycobacterium tuberculosis 1615, Mycobacterium tuberculosis 6605, Mycobacterium tuberculosis 7057, Mycobacterium tuberculosis XTB13-299, Mycobacterium tuberculosis XTB13-290, Mycobacterium tuberculosis XTB13-278, Mycobacterium tuberculosis XTB13-265, Mycobacterium tuberculosis XTB13-262, Mycobacterium tuberculosis XTB13-255, Mycobacterium tuberculosis XTB13-256, Mycobacterium tuberculosis XTB13-253, Mycobacterium tuberculosis XTB13-252, Mycobacterium tuberculosis XTB13-251, Mycobacterium tuberculosis XTB13-249, Mycobacterium tuberculosis XTB13-250, Mycobacterium tuberculosis XTB13-247, Mycobacterium tuberculosis XTB13-245, Mycobacterium tuberculosis XTB13-246, Mycobacterium tuberculosis XTB13-244, Mycobacterium tuberculosis XTB13-242, Mycobacterium tuberculosis XTB13-241, Mycobacterium tuberculosis XTB13-238, Mycobacterium tuberculosis XTB13-240, Mycobacterium tuberculosis XTB13-239, Mycobacterium tuberculosis XTB13-235, Mycobacterium tuberculosis XTB13-234, Mycobacterium tuberculosis XTB13-237, Mycobacterium tuberculosis XTB13-233, Mycobacterium tuberculosis XTB13-232, Mycobacterium tuberculosis XTB13-231, Mycobacterium tuberculosis XTB13-230, Mycobacterium tuberculosis XTB13-229, Mycobacterium tuberculosis XTB13-228, Mycobacterium tuberculosis XTB13-227, Mycobacterium tuberculosis XTB13-225, Mycobacterium tuberculosis XTB13-219, Mycobacterium tuberculosis XTB13-217, Mycobacterium tuberculosis XTB13-218, Mycobacterium tuberculosis XTB13-216, Mycobacterium tuberculosis XTB13-214, Mycobacterium tuberculosis XTB13-213, Mycobacterium tuberculosis XTB13-212, Mycobacterium tuberculosis XTB13-211, Mycobacterium tuberculosis XTB13-210, Mycobacterium tuberculosis XTB13-208, Mycobacterium tuberculosis XTB13-209, Mycobacterium tuberculosis XTB13-204, Mycobacterium tuberculosis XTB13-206, Mycobacterium tuberculosis XTB13-205, Mycobacterium tuberculosis XTB13-203, Mycobacterium tuberculosis XTB13-199, Mycobacterium tuberculosis XTB13-200, Mycobacterium tuberculosis XTB13-198, Mycobacterium tuberculosis XTB13-196, Mycobacterium tuberculosis XTB13-197, Mycobacterium tuberculosis XTB13-193, Mycobacterium tuberculosis XTB13-195, Mycobacterium tuberculosis XTB13-194, Mycobacterium tuberculosis XTB13-192, Mycobacterium tuberculosis XTB13-191, Mycobacterium tuberculosis XTB13-190, Mycobacterium tuberculosis XTB13-186, Mycobacterium tuberculosis XTB13-188, Mycobacterium tuberculosis XTB13-187, Mycobacterium tuberculosis XTB13-183, Mycobacterium tuberculosis XTB13-182, Mycobacterium tuberculosis XTB13-184, Mycobacterium tuberculosis XTB13-180, Mycobacterium tuberculosis TB_RSA76, Mycobacterium tuberculosis TB_RSA74, Mycobacterium tuberculosis TB_RSA75, Mycobacterium tuberculosis TB_RSA73, Mycobacterium tuberculosis TB_RSA71, Mycobacterium tuberculosis TB_RSA72, Mycobacterium tuberculosis TB_RSA70, Mycobacterium tuberculosis TB_RSA69, Mycobacterium tuberculosis TB_RSA67, Mycobacterium tuberculosis TB_RSA68, Mycobacterium tuberculosis TB_RSA64, Mycobacterium tuberculosis TB_RSA63, Mycobacterium tuberculosis TB_RSA58, Mycobacterium tuberculosis TB_RSA59, Mycobacterium tuberculosis TB_RSA60, Mycobacterium tuberculosis TB_RSA56, Mycobacterium tuberculosis TB_RSA57, Mycobacterium tuberculosis TB_RSA55, Mycobacterium tuberculosis TB_RSA51, Mycobacterium tuberculosis TB_RSA53, Mycobacterium tuberculosis TB_RSA50, Mycobacterium tuberculosis TB_RSA46, Mycobacterium tuberculosis TB_RSA49, Mycobacterium tuberculosis TB_RSA48, Mycobacterium tuberculosis TB_RSA45, Mycobacterium tuberculosis TB_RSA44, Mycobacterium tuberculosis TB_RSA43, Mycobacterium tuberculosis TB_RSA42, Mycobacterium tuberculosis TB_RSA41, Mycobacterium tuberculosis TB_RSA38, Mycobacterium tuberculosis TB_RSA40, Mycobacterium tuberculosis TB_RSA39, Mycobacterium tuberculosis TB_RSA36, Mycobacterium tuberculosis TB_RSA35, Mycobacterium tuberculosis TB_RSA37, Mycobacterium tuberculosis TB_RSA33, Mycobacterium tuberculosis TB_RSA32, Mycobacterium tuberculosis TB_RSA34, Mycobacterium tuberculosis TB_RSA28, Mycobacterium tuberculosis TB_RSA31, Mycobacterium tuberculosis TB_RSA30, Mycobacterium tuberculosis TB_RSA29, Mycobacterium tuberculosis TB_RSA27, Mycobacterium tuberculosis TB_RSA26, Mycobacterium tuberculosis TB_RSA24, Mycobacterium tuberculosis TB_RSA23, Mycobacterium tuberculosis TB_RSA22, Mycobacterium tuberculosis TB_RSA20, Mycobacterium tuberculosis TB_RSA21, Mycobacterium tuberculosis TB_RSA19, Mycobacterium tuberculosis TB_RSA17, Mycobacterium tuberculosis TB_RSA18, Mycobacterium tuberculosis TB_RSA16, Mycobacterium tuberculosis TB_RSA15, Mycobacterium tuberculosis TB_RSA14, Mycobacterium tuberculosis TB_RSA11, Mycobacterium tuberculosis TB_RSA13, Mycobacterium tuberculosis TB_RSA12, Mycobacterium tuberculosis TB_RSA10, Mycobacterium tuberculosis TB_RSA09, Mycobacterium tuberculosis TB_RSA08, Mycobacterium tuberculosis TB_RSA07, Mycobacterium tuberculosis TB_RSA06, Mycobacterium tuberculosis TB_RSA05, Mycobacterium tuberculosis TB_RSA04, Mycobacterium tuberculosis TB_RSA02, Mycobacterium tuberculosis TB_RSA03, Mycobacterium tuberculosis 38088, Mycobacterium tuberculosis TB_RSA01, Mycobacterium tuberculosis 36361, Mycobacterium tuberculosis 51628, Mycobacterium tuberculosis 49375, Mycobacterium tuberculosis 44503, Mycobacterium tuberculosis 38765, Mycobacterium tuberculosis CDC1551, Mycobacterium tuberculosis KT-0087, Mycobacterium tuberculosis KZN 1435, Mycobacterium tuberculosis KZN 4207, Mycobacterium tuberculosis XDR KZN 605, Mycobacterium tuberculosis KT-0082, Mycobacterium tuberculosis KT-0086, Mycobacterium tuberculosis KT-0069, Mycobacterium tuberculosis KT-0060, Mycobacterium tuberculosis KT-0034, Mycobacterium tuberculosis KT-0042, Mycobacterium tuberculosis KT-0032, Mycobacterium tuberculosis KT-0033, Mycobacterium tuberculosis KT-0031, Mycobacterium tuberculosis KT-0029, Mycobacterium tuberculosis KT-0020, Mycobacterium tuberculosis KT-0025, Mycobacterium tuberculosis KT-0012, Mycobacterium tuberculosis KT-0010, Mycobacterium tuberculosis KT-0004, Mycobacterium tuberculosis TRUG0017, Mycobacterium tuberculosis TRUG0125, Mycobacterium tuberculosis TRUG0116, Mycobacterium tuberculosis TRUG0117, Mycobacterium tuberculosis TRUG0124, Mycobacterium tuberculosis TRUG0114, Mycobacterium tuberculosis TRUG0113, Mycobacterium tuberculosis TRUG0107, Mycobacterium tuberculosis TRUG0111, Mycobacterium tuberculosis TRUG0105, Mycobacterium tuberculosis TRUG0106, Mycobacterium tuberculosis TRUG0097, Mycobacterium tuberculosis TRUG0098, Mycobacterium tuberculosis TRUG0101, Mycobacterium tuberculosis TRUG0095, Mycobacterium tuberculosis TRUG0093, Mycobacterium tuberculosis TRUG0094, Mycobacterium tuberculosis TRUG0092, Mycobacterium tuberculosis TRUG0091, Mycobacterium tuberculosis TRUG0090, Mycobacterium tuberculosis TRUG0089, Mycobacterium tuberculosis TRUG0086, Mycobacterium tuberculosis TRUG0088, Mycobacterium tuberculosis TRUG0085, Mycobacterium tuberculosis TRUG0081, Mycobacterium tuberculosis TRUG0084, Mycobacterium tuberculosis TRUG0083, Mycobacterium tuberculosis TRUG0080, Mycobacterium tuberculosis TRUG0078, Mycobacterium tuberculosis TRUG0068, Mycobacterium tuberculosis TRUG0072, Mycobacterium tuberculosis TRUG0071, Mycobacterium tuberculosis TRUG0070, Mycobacterium tuberculosis TRUG0061, Mycobacterium tuberculosis TRUG0060, Mycobacterium tuberculosis TRUG0057, Mycobacterium tuberculosis TRUG0059, Mycobacterium tuberculosis TRUG0058, Mycobacterium tuberculosis TRUG0056, Mycobacterium tuberculosis TRUG0054, Mycobacterium tuberculosis TRUG0053, Mycobacterium tuberculosis TRUG0049, Mycobacterium tuberculosis TRUG0052, Mycobacterium tuberculosis TRUG0051, Mycobacterium tuberculosis TRUG0045, Mycobacterium tuberculosis TRUG0046, Mycobacterium tuberculosis TRUG0041, Mycobacterium tuberculosis TRUG0040, Mycobacterium tuberculosis TRUG0038, Mycobacterium tuberculosis TRUG0034, Mycobacterium tuberculosis TRUG0037, Mycobacterium tuberculosis TRUG0036, Mycobacterium tuberculosis TRUG0030, Mycobacterium tuberculosis str. Erdman, Mycobacterium tuberculosis OFXR-33, Mycobacterium tuberculosis OFXR-32, Mycobacterium tuberculosis OFXR-31, Mycobacterium tuberculosis OFXR-29, Mycobacterium tuberculosis OFXR-30, Mycobacterium tuberculosis OFXR-27, Mycobacterium tuberculosis OFXR-26, Mycobacterium tuberculosis OFXR-23, Mycobacterium tuberculosis OFXR-25, Mycobacterium tuberculosis OFXR-21, Mycobacterium tuberculosis OFXR-22, Mycobacterium tuberculosis OFXR-19, Mycobacterium tuberculosis OFXR-18, Mycobacterium tuberculosis OFXR-20, Mycobacterium tuberculosis OFXR-9, Mycobacterium tuberculosis OFXR-17, Mycobacterium tuberculosis OFXR-8, Mycobacterium tuberculosis OFXR-6, Mycobacterium tuberculosis OFXR-1, Mycobacterium tuberculosis F11, Mycobacterium tuberculosis str. Haarlem, Mycobacterium tuberculosis MAL020211, Mycobacterium tuberculosis MAL020208, Mycobacterium tuberculosis MAL020209, Mycobacterium tuberculosis MAL020206, Mycobacterium tuberculosis MAL020201, Mycobacterium tuberculosis MAL020202, Mycobacterium tuberculosis MAL020200, Mycobacterium tuberculosis MAL020199, Mycobacterium tuberculosis MAL020196, Mycobacterium tuberculosis MAL020197, Mycobacterium tuberculosis MAL020194, Mycobacterium tuberculosis MAL020195, Mycobacterium tuberculosis MAL020193, Mycobacterium tuberculosis MAL020192, Mycobacterium tuberculosis MAL020187, Mycobacterium tuberculosis MAL020186, Mycobacterium africanum MAL020185, Mycobacterium tuberculosis MAL020182, Mycobacterium tuberculosis MAL020181, Mycobacterium tuberculosis MAL020179, Mycobacterium tuberculosis MAL020174, Mycobacterium tuberculosis MAL020167, Mycobacterium africanum MAL020176, Mycobacterium africanum MAL020173, Mycobacterium tuberculosis MAL020172, Mycobacterium tuberculosis MAL020160, Mycobacterium tuberculosis MAL020162, Mycobacterium tuberculosis MAL020156, Mycobacterium tuberculosis MAL020157, Mycobacterium tuberculosis MAL020152, Mycobacterium tuberculosis MAL020147, Mycobacterium tuberculosis MAL020150, Mycobacterium tuberculosis MAL020144, Mycobacterium tuberculosis MAL020146, Mycobacterium tuberculosis MAL020142, Mycobacterium tuberculosis MAL020145, Mycobacterium tuberculosis MAL020141, Mycobacterium tuberculosis MAL020138, Mycobacterium tuberculosis MAL020136, Mycobacterium tuberculosis MAL020132, Mycobacterium africanum MAL020135, Mycobacterium tuberculosis MAL020131, Mycobacterium africanum MAL020130, Mycobacterium tuberculosis MAL020120, Mycobacterium tuberculosis MAL010134, Mycobacterium tuberculosis MAL020110, Mycobacterium africanum MAL020107, Mycobacterium africanum MAL010137, Mycobacterium africanum MAL010136, Mycobacterium tuberculosis MAL010133, Mycobacterium africanum MAL010131, Mycobacterium africanum MAL010129, Mycobacterium tuberculosis MAL010130, Mycobacterium africanum MAL010128, Mycobacterium africanum MAL010123, Mycobacterium tuberculosis MAL010121, Mycobacterium africanum MAL010118, Mycobacterium africanum MAL010120, Mycobacterium africanum MAL010112, Mycobacterium tuberculosis MAL010109, Mycobacterium africanum MAL010111, Mycobacterium tuberculosis MAL010110, Mycobacterium tuberculosis MAL010108, Mycobacterium tuberculosis MAL010105, Mycobacterium tuberculosis MAL010106, Mycobacterium africanum MAL010102, Mycobacterium tuberculosis MAL010103, Mycobacterium africanum MAL010100, Mycobacterium bovis MAL010093, Mycobacterium tuberculosis MAL010088, Mycobacterium africanum MAL010099, Mycobacterium tuberculosis MAL010087, Mycobacterium tuberculosis MAL010086, Mycobacterium tuberculosis MAL010080, Mycobacterium africanum MAL010079, Mycobacterium africanum MAL010081, Mycobacterium tuberculosis MAL010078, Mycobacterium africanum MAL010071, Mycobacterium africanum MAL010074, Mycobacterium africanum MAL010070, Mycobacterium africanum, Mycobacterium tuberculosis GM 1503, Mycobacterium tuberculosis T46, Mycobacterium tuberculosis 94_M4241A, Mycobacterium tuberculosis T17, Mycobacterium tuberculosis CPHL_A, Mycobacterium tuberculosis EAS054, Mycobacterium tuberculosis T85, Mycobacterium tuberculosis K85, Mycobacterium tuberculosis M2350, Mycobacterium tuberculosis M13, Mycobacterium tuberculosis T92, Mycobacterium tuberculosis M2828, Mycobacterium tuberculosis M2346, Mycobacterium tuberculosis H3367, Mycobacterium tuberculosis H2398, Mycobacterium tuberculosis H2264, Mycobacterium tuberculosis H2581, Mycobacterium tuberculosis H1996, Mycobacterium tuberculosis H1249, Mycobacterium tuberculosis H3986, Mycobacterium tuberculosis H3094, Mycobacterium tuberculosis H2754, Mycobacterium tuberculosis H2463, Mycobacterium tuberculosis H3361, Mycobacterium tuberculosis H3360, Mycobacterium tuberculosis H3033, Mycobacterium tuberculosis H3005, Mycobacterium tuberculosis H3004, Mycobacterium tuberculosis H2760, Mycobacterium tuberculosis H2438, Mycobacterium tuberculosis H2300, Mycobacterium tuberculosis H2102, Mycobacterium tuberculosis H2101, Mycobacterium tuberculosis H1856, Mycobacterium tuberculosis H1589, Mycobacterium tuberculosis H1580, Mycobacterium tuberculosis H1578, Mycobacterium tuberculosis H1329, Mycobacterium tuberculosis M2508, Mycobacterium tuberculosis M2384, Mycobacterium tuberculosis M2479, Mycobacterium tuberculosis M2144, Mycobacterium tuberculosis M2145, Mycobacterium tuberculosis M2360, Mycobacterium tuberculosis M2361, Mycobacterium tuberculosis M2376, Mycobacterium tuberculosis M2402, Mycobacterium tuberculosis M2416, Mycobacterium tuberculosis M2435, Mycobacterium tuberculosis M2440, Mycobacterium tuberculosis M2442, Mycobacterium tuberculosis M2459, Mycobacterium tuberculosis M2142, Mycobacterium tuberculosis M2249, Mycobacterium tuberculosis M2259, Mycobacterium tuberculosis M2276, Mycobacterium tuberculosis M2277, Mycobacterium tuberculosis M2278, Mycobacterium tuberculosis M2323, Mycobacterium tuberculosis M2324, Mycobacterium tuberculosis M2342, Mycobacterium tuberculosis M2343, Mycobacterium tuberculosis M2141, Mycobacterium tuberculosis M2191, Mycobacterium tuberculosis M2192, Mycobacterium tuberculosis M2198, Mycobacterium tuberculosis M2199, Mycobacterium tuberculosis M2203, Mycobacterium tuberculosis M2204, Mycobacterium tuberculosis M2206, Mycobacterium tuberculosis M2211, Mycobacterium tuberculosis M2218, Mycobacterium tuberculosis M2248, Mycobacterium tuberculosis M2140, Mycobacterium tuberculosis M2138, Mycobacterium tuberculosis M2139, Mycobacterium tuberculosis M2137, Mycobacterium tuberculosis M2136, Mycobacterium tuberculosis M2134, Mycobacterium tuberculosis M2132, Mycobacterium tuberculosis M2131, Mycobacterium tuberculosis M2130, Mycobacterium tuberculosis M2129, Mycobacterium tuberculosis M2128, Mycobacterium tuberculosis M2116, Mycobacterium tuberculosis M2113, Mycobacterium tuberculosis M2086, Mycobacterium tuberculosis M2085, Mycobacterium tuberculosis M2032, Mycobacterium tuberculosis M2021, Mycobacterium tuberculosis M2020, Mycobacterium tuberculosis M2010, Mycobacterium tuberculosis M2007, Mycobacterium tuberculosis M2006, Mycobacterium tuberculosis M2003, Mycobacterium tuberculosis M1979, Mycobacterium tuberculosis M1978, Mycobacterium tuberculosis M1976, Mycobacterium tuberculosis M1973, Mycobacterium tuberculosis M1967, Mycobacterium tuberculosis M1961, Mycobacterium tuberculosis M1959, Mycobacterium tuberculosis M1956, Mycobacterium tuberculosis M1955, Mycobacterium tuberculosis M1948, Mycobacterium tuberculosis M1932, Mycobacterium tuberculosis M1929, Mycobacterium tuberculosis M1928, Mycobacterium tuberculosis M1914, Mycobacterium tuberculosis M1913, Mycobacterium tuberculosis M1906, Mycobacterium tuberculosis M1895, Mycobacterium tuberculosis M1893, Mycobacterium tuberculosis M1848, Mycobacterium tuberculosis M1822, Mycobacterium tuberculosis M1816, Mycobacterium tuberculosis M1782, Mycobacterium tuberculosis M1787, Mycobacterium tuberculosis M1780, Mycobacterium tuberculosis M1762, Mycobacterium tuberculosis M1734, Mycobacterium tuberculosis M1728, Mycobacterium tuberculosis M1726, Mycobacterium tuberculosis M1704, Mycobacterium tuberculosis M1703, Mycobacterium tuberculosis M1702, Mycobacterium tuberculosis M1638, Mycobacterium tuberculosis M1615, Mycobacterium tuberculosis M1570, Mycobacterium tuberculosis M1560, Mycobacterium tuberculosis M1559, Mycobacterium tuberculosis M1545, Mycobacterium tuberculosis M1520, Mycobacterium tuberculosis M1533, Mycobacterium tuberculosis M1488, Mycobacterium tuberculosis M1481, Mycobacterium tuberculosis M1461, Mycobacterium tuberculosis M1475, Mycobacterium tuberculosis M1458, Mycobacterium tuberculosis M1459, Mycobacterium tuberculosis M1456, Mycobacterium tuberculosis M1452, Mycobacterium tuberculosis M1449, Mycobacterium tuberculosis M1700, Mycobacterium tuberculosis M1448, Mycobacterium tuberculosis M1444, Mycobacterium tuberculosis M1441, Mycobacterium tuberculosis M1429, Mycobacterium tuberculosis M1439, Mycobacterium tuberculosis M1438, Mycobacterium tuberculosis M1425, Mycobacterium tuberculosis M1431, Mycobacterium tuberculosis M1418, Mycobacterium tuberculosis M1422, Mycobacterium tuberculosis M1424, Mycobacterium tuberculosis M1417, Mycobacterium tuberculosis M1415, Mycobacterium tuberculosis M1416, Mycobacterium tuberculosis M1410, Mycobacterium tuberculosis M1404, Mycobacterium tuberculosis M1397, Mycobacterium tuberculosis M1400, Mycobacterium tuberculosis M1402, Mycobacterium tuberculosis M1393, Mycobacterium tuberculosis M1384, Mycobacterium tuberculosis M1392, Mycobacterium tuberculosis M1381, Mycobacterium tuberculosis M1389, Mycobacterium tuberculosis M1374, Mycobacterium tuberculosis M1373, Mycobacterium tuberculosis M1325, Mycobacterium tuberculosis M1324, Mycobacterium tuberculosis M1340, Mycobacterium tuberculosis M1317, Mycobacterium tuberculosis M1319, Mycobacterium tuberculosis M1315, Mycobacterium tuberculosis M1309, Mycobacterium tuberculosis M1304, Mycobacterium tuberculosis M1310, Mycobacterium tuberculosis M1300, Mycobacterium tuberculosis M1294, Mycobacterium tuberculosis M1295, Mycobacterium tuberculosis M1292, Mycobacterium tuberculosis M1288, Mycobacterium tuberculosis M1272, Mycobacterium tuberculosis M1287, Mycobacterium tuberculosis M1274, Mycobacterium tuberculosis M1273, Mycobacterium tuberculosis M1283, Mycobacterium tuberculosis M1270, Mycobacterium tuberculosis M1236, Mycobacterium tuberculosis M1271, Mycobacterium tuberculosis M1253, Mycobacterium tuberculosis M1233, Mycobacterium tuberculosis M1221, Mycobacterium tuberculosis M1232, Mycobacterium tuberculosis M1212, Mycobacterium tuberculosis M1213, Mycobacterium tuberculosis M1215, Mycobacterium tuberculosis M1034, Mycobacterium tuberculosis M1025, Mycobacterium tuberculosis M1210, Mycobacterium tuberculosis M1026, Mycobacterium tuberculosis M1024, Mycobacterium tuberculosis M1022, Mycobacterium tuberculosis M1017, Mycobacterium tuberculosis M1023, Mycobacterium tuberculosis M1011, Mycobacterium tuberculosis M1021, Mycobacterium tuberculosis M1010, Mycobacterium tuberculosis M1012, Mycobacterium tuberculosis M1009, Mycobacterium tuberculosis M992, Mycobacterium tuberculosis M1008, Mycobacterium tuberculosis M1007, Mycobacterium tuberculosis M995, Mycobacterium tuberculosis M991, Mycobacterium tuberculosis M1004, Mycobacterium tuberculosis M990, Mycobacterium tuberculosis M987, Mycobacterium tuberculosis M984, Mycobacterium tuberculosis TKK_04_0120, Mycobacterium tuberculosis TKK_04_0123, Mycobacterium tuberculosis TKK_04_0114, Mycobacterium tuberculosis TKK_04_0122, Mycobacterium tuberculosis TKK_04_0117, Mycobacterium tuberculosis TKK_04_0113, Mycobacterium tuberculosis TKK_04_0107, Mycobacterium tuberculosis TKK_04_0109, Mycobacterium tuberculosis TKK_04_0103, Mycobacterium tuberculosis TKK_04_0106, Mycobacterium tuberculosis TKK_04_0098, Mycobacterium tuberculosis TKK_04_0105, Mycobacterium tuberculosis TKK_04_0096, Mycobacterium tuberculosis TKK_04_0099, Mycobacterium tuberculosis TKK_04_0094, Mycobacterium tuberculosis TKK_04_0090, Mycobacterium tuberculosis TKK_04_0089, Mycobacterium tuberculosis TKK_04_0085, Mycobacterium tuberculosis TKK_05SA_0058, Mycobacterium tuberculosis TKK_05SA_0055, Mycobacterium tuberculosis TKK_05SA_0054, Mycobacterium tuberculosis TKK_05SA_0052, Mycobacterium tuberculosis TKK_05SA_0050, Mycobacterium tuberculosis TKK_05SA_0048, Mycobacterium tuberculosis TKK_05SA_0047, Mycobacterium tuberculosis TKK_05SA_0046, Mycobacterium tuberculosis TKK_05SA_0044, Mycobacterium tuberculosis TKK_05SA_0042, Mycobacterium tuberculosis TKK_05SA_0041, Mycobacterium tuberculosis TKK_05SA_0043, Mycobacterium tuberculosis TKK_05SA_0036, Mycobacterium tuberculosis TKK_05SA_0031, Mycobacterium tuberculosis TKK_05SA_0025, Mycobacterium tuberculosis TKK_05SA_0023, Mycobacterium tuberculosis TKK_05SA_0021, Mycobacterium tuberculosis TKK_05SA_0019, Mycobacterium tuberculosis TKK_05SA_0018, Mycobacterium tuberculosis TKK_05SA_0017, Mycobacterium tuberculosis TKK_05SA_0014, Mycobacterium tuberculosis TKK_05SA_0010, Mycobacterium tuberculosis TKK_05MA_2015, Mycobacterium tuberculosis TKK_05MA_0058, Mycobacterium tuberculosis TKK_05MA_2008, Mycobacterium tuberculosis TKK_05MA_2005, Mycobacterium tuberculosis TKK_05MA_0052, Mycobacterium tuberculosis TKK_05MA_0048, Mycobacterium tuberculosis TKK_05MA_0046, Mycobacterium tuberculosis TKK_05MA_0044, Mycobacterium tuberculosis TKK_05MA_0040, Mycobacterium tuberculosis TKK_05MA_0036, Mycobacterium tuberculosis TKK_05MA_0037, Mycobacterium tuberculosis TKK_05MA_0033, Mycobacterium tuberculosis TKK_05MA_0031, Mycobacterium tuberculosis TKK_05MA_0025, Mycobacterium tuberculosis TKK_05MA_0020, Mycobacterium tuberculosis TKK_05MA_0026, Mycobacterium tuberculosis TKK_05MA_0018, Mycobacterium tuberculosis TKK_05MA_0017, Mycobacterium tuberculosis TKK_05MA_0011, Mycobacterium tuberculosis TKK_05MA_0010, Mycobacterium tuberculosis TKK_04_0086, Mycobacterium tuberculosis TKK_04_0084, Mycobacterium tuberculosis TKK_05MA_0001, Mycobacterium tuberculosis TKK_04_0083, Mycobacterium tuberculosis TKK_04_0082, Mycobacterium tuberculosis TKK_04_0080, Mycobacterium tuberculosis TKK_04_0079, Mycobacterium tuberculosis TKK_04_0081, Mycobacterium tuberculosis TKK_04_0075, Mycobacterium tuberculosis TKK_04_0072, Mycobacterium tuberculosis TKK_04_0078, Mycobacterium tuberculosis TKK_04_0071, Mycobacterium tuberculosis TKK_04_0069, Mycobacterium tuberculosis TKK_04_0070, Mycobacterium tuberculosis TKK_04_0067, Mycobacterium tuberculosis TKK_04_0068, Mycobacterium tuberculosis TKK_04_0066, Mycobacterium tuberculosis TKK_04_0063, Mycobacterium tuberculosis TKK_04_0061, Mycobacterium tuberculosis TKK_04_0064, Mycobacterium tuberculosis TKK_04_0060, Mycobacterium tuberculosis TKK_04_0054, Mycobacterium tuberculosis TKK_04_0059, Mycobacterium tuberculosis TKK_03_0160, Mycobacterium tuberculosis TKK_03_0158, Mycobacterium tuberculosis TKK_04_0051, Mycobacterium tuberculosis TKK_03_0156, Mycobacterium tuberculosis TKK_03_0159, Mycobacterium tuberculosis TKK_03_0154, Mycobacterium tuberculosis TKK_03_0153, Mycobacterium tuberculosis TKK_03_0150, Mycobacterium tuberculosis TKK_03_0149, Mycobacterium tuberculosis TKK_03_0116, Mycobacterium tuberculosis TKK_03_0118, Mycobacterium tuberculosis TKK_03_0113, Mycobacterium tuberculosis TKK_03_0115, Mycobacterium tuberculosis TKK_03_0114, Mycobacterium tuberculosis TKK_03_0112, Mycobacterium tuberculosis TKK_03_0111, Mycobacterium tuberculosis TKK_03_0109, Mycobacterium tuberculosis TKK_03_0108, Mycobacterium tuberculosis TKK_03_0105, Mycobacterium tuberculosis TKK_03_0106, Mycobacterium tuberculosis TKK_03_0103, Mycobacterium tuberculosis TKK_03_0100, Mycobacterium tuberculosis TKK_03_0101, Mycobacterium tuberculosis TKK_03_0098, Mycobacterium tuberculosis TKK_03_0096, Mycobacterium tuberculosis TKK_03_0099, Mycobacterium tuberculosis TKK_03_0094, Mycobacterium tuberculosis TKK_03_0090, Mycobacterium tuberculosis TKK_03_0092, Mycobacterium tuberculosis TKK_03_0089, Mycobacterium tuberculosis TKK_03_0083, Mycobacterium tuberculosis TKK_03_0064, Mycobacterium tuberculosis TKK_03_0075, Mycobacterium tuberculosis TKK_03_0072, Mycobacterium tuberculosis TKK_03_0065, Mycobacterium tuberculosis TKK_03_0062, Mycobacterium tuberculosis TKK_03_0063, Mycobacterium tuberculosis TKK_03_0059, Mycobacterium tuberculosis TKK_03_0047, Mycobacterium tuberculosis TKK_03_0058, Mycobacterium tuberculosis TKK_03_0050, Mycobacterium tuberculosis TKK_03_0044, Mycobacterium tuberculosis TKK_03_0042, Mycobacterium tuberculosis TKK_03_0040, Mycobacterium tuberculosis TKK_03_0038, Mycobacterium tuberculosis TKK_03_0039, Mycobacterium tuberculosis TKK_03_0037, Mycobacterium tuberculosis TKK_03_0035, Mycobacterium tuberculosis TKK_03_0024, Mycobacterium tuberculosis TKK_03_0028, Mycobacterium tuberculosis TKK_03_0023, Mycobacterium tuberculosis TKK_03_0021, Mycobacterium tuberculosis TKK_03_0015, Mycobacterium tuberculosis MD15762, Mycobacterium tuberculosis TKK_03_0012, Mycobacterium tuberculosis MD15765, Mycobacterium tuberculosis MD15758, Mycobacterium tuberculosis MD15584, Mycobacterium tuberculosis MD16573, Mycobacterium tuberculosis MD14437, Mycobacterium tuberculosis MD15212, Mycobacterium tuberculosis MD14720, Mycobacterium tuberculosis MD15597, Mycobacterium tuberculosis MD14709, Mycobacterium tuberculosis MD14435, Mycobacterium tuberculosis MD14002, Mycobacterium tuberculosis MD13878, Mycobacterium tuberculosis MD15973, Mycobacterium tuberculosis MD14621, Mycobacterium tuberculosis MD13874, Mycobacterium tuberculosis MD14832, Mycobacterium tuberculosis MD15050, Mycobacterium tuberculosis MD14847, Mycobacterium tuberculosis MD14620, Mycobacterium tuberculosis MD14844, Mycobacterium tuberculosis MD16257, Mycobacterium tuberculosis MD15963, Mycobacterium tuberculosis MD15855, Mycobacterium tuberculosis MD15770, Mycobacterium tuberculosis MD15977, Mycobacterium tuberculosis MD15956, Mycobacterium tuberculosis MD17232, Mycobacterium tuberculosis MD17006, Mycobacterium tuberculosis MD15430, Mycobacterium tuberculosis MD16571, Mycobacterium tuberculosis MD16568, Mycobacterium tuberculosis MD15226, Mycobacterium tuberculosis MD16265, Mycobacterium tuberculosis MD15974, Mycobacterium tuberculosis MD15766, Mycobacterium tuberculosis MD16553, Mycobacterium tuberculosis MD16277, Mycobacterium tuberculosis MD16577, Mycobacterium tuberculosis MD17888, Mycobacterium tuberculosis MD17656, Mycobacterium tuberculosis MD17240, Mycobacterium tuberculosis MD16775, Mycobacterium tuberculosis MD17613, Mycobacterium tuberculosis MD17647, Mycobacterium tuberculosis MD17517, Mycobacterium tuberculosis MD17503, Mycobacterium tuberculosis MD17021, Mycobacterium tuberculosis MD16732, Mycobacterium tuberculosis MD16261, Mycobacterium tuberculosis MD18314, Mycobacterium tuberculosis MD18090, Mycobacterium tuberculosis MD18116, Mycobacterium tuberculosis MD18498, Mycobacterium tuberculosis MD16728, Mycobacterium tuberculosis MD15594, Mycobacterium tuberculosis MD17903, Mycobacterium tuberculosis MD17973, Mycobacterium tuberculosis MD18112, Mycobacterium tuberculosis MD18096, Mycobacterium tuberculosis MD19051, Mycobacterium tuberculosis MD19323, Mycobacterium tuberculosis MD18472, Mycobacterium tuberculosis MD19591, Mycobacterium tuberculosis MD19339, Mycobacterium tuberculosis MD20845, Mycobacterium tuberculosis MD19043, Mycobacterium tuberculosis MD17748, Mycobacterium tuberculosis MD17615, Mycobacterium tuberculosis MD17614, Mycobacterium tuberculosis MD19042, Mycobacterium tuberculosis MD19693, Mycobacterium tuberculosis MD19964, Mycobacterium tuberculosis MD18489, Mycobacterium tuberculosis MD18478, Mycobacterium tuberculosis MD16555, Mycobacterium tuberculosis MD17902, Mycobacterium tuberculosis MD17904, Mycobacterium tuberculosis MD17898, Mycobacterium bovis B2 7505, Mycobacterium bovis Kc 9614, Mycobacterium bovis Mr 4387, Mycobacterium bovis Wt 21419, Mycobacterium bovis Bz 31150, Mycobacterium tuberculosis 1010SM, Mycobacterium bovis Wt 21231, Mycobacterium tuberculosis 1173CS, Mycobacterium tuberculosis 1429BH, Mycobacterium tuberculosis 1430BH, Mycobacterium tuberculosis 1755BN, Mycobacterium tuberculosis 3499MM, Mycobacterium tuberculosis 2088HD, Mycobacterium tuberculosis 2089HD, Mycobacterium tuberculosis 2541MS, Mycobacterium tuberculosis 2543MS, Mycobacterium tuberculosis 2091HD, Mycobacterium tuberculosis 2099HD, Mycobacterium tuberculosis 2093HD, Mycobacterium tuberculosis 2094HD, Mycobacterium tuberculosis 2100HD, Mycobacterium tuberculosis 2228BH, Mycobacterium tuberculosis 3067CJ, Mycobacterium tuberculosis 2229BH, Mycobacterium tuberculosis 2074CJ, Mycobacterium tuberculosis 2230BH, Mycobacterium tuberculosis 2484AR, Mycobacterium tuberculosis TKK_04_0157, Mycobacterium tuberculosis TKK_04_0141, Mycobacterium tuberculosis TKK_04_0118, Mycobacterium tuberculosis TKK_04_0112, Mycobacterium tuberculosis TKK_04_0097, Mycobacterium tuberculosis TKK_04_0108, Mycobacterium tuberculosis TKK_04_0095, Mycobacterium tuberculosis TKK_05SA_0026, Mycobacterium tuberculosis TKK_05SA_0020, Mycobacterium tuberculosis TKK_05SA_0011, Mycobacterium tuberculosis TKK_05MA_0051, Mycobacterium tuberculosis TKK_05MA_0009, Mycobacterium bovis Kc 32216, Mycobacterium tuberculosis TKK_04_0062, Mycobacterium tuberculosis 2196MM, Mycobacterium bovis D 4155, Mycobacterium tuberculosis 2101HD, Mycobacterium tuberculosis 2483AR, Mycobacterium tuberculosis 2482AR, Mycobacterium tuberculosis 2485AR, Mycobacterium tuberculosis BTB07-168, Mycobacterium tuberculosis M2352, Mycobacterium tuberculosis M1926, Mycobacterium tuberculosis M1030, Mycobacterium tuberculosis M1029, Mycobacterium tuberculosis TB_RSA54, Mycobacterium tuberculosis 02_1987, Mycobacterium tuberculosis MD16765, Mycobacterium tuberculosis MD17749, Mycobacterium tuberculosis MD16764, Mycobacterium tuberculosis MD20344, Mycobacterium tuberculosis MD18486, Mycobacterium tuberculosis MD18320, Mycobacterium tuberculosis XTB13-173, Mycobacterium tuberculosis XTB13-123, Mycobacterium tuberculosis 7837, Mycobacterium tuberculosis XTB13-142, Mycobacterium tuberculosis XTB13-110, Mycobacterium tuberculosis 16954, Mycobacterium tuberculosis 9542, Mycobacterium tuberculosis KT-0081, Mycobacterium tuberculosis KT-0067, Mycobacterium tuberculosis KT-0040, Mycobacterium tuberculosis KT-0037, Mycobacterium tuberculosis KT-0018, Mycobacterium tuberculosis TRUG0076, Mycobacterium tuberculosis TRUG0026, Mycobacterium tuberculosis TRUG0047, Mycobacterium tuberculosis SK-B, Mycobacterium tuberculosis TKK-01-0036, Mycobacterium tuberculosis CWCFVRF MDRTB 670, Mycobacterium bovis BCG str. ATCC 35743, Mycobacterium tuberculosis CCDC5180, Mycobacterium tuberculosis BT1, Mycobacterium tuberculosis BT2, Mycobacterium tuberculosis HKBS1, Mycobacterium tuberculosis INS_XDR, Mycobacterium tuberculosis INS_MDR, Mycobacterium tuberculosis INS_SEN, Mycobacterium bovis 04-303, Mycobacterium bovis AN5, Mycobacterium tuberculosis FJ05194, Mycobacterium tuberculosis GuangZ0019, Mycobacterium tuberculosis '98-R604 INH-RIF-EM', Mycobacterium tuberculosis EAI5, Mycobacterium tuberculosis CCDC5079, Mycobacterium tuberculosis EAI5/NITR206, Mycobacterium tuberculosis str. Beijing/NITR203, Mycobacterium tuberculosis KZN 605, Mycobacterium tuberculosis RGTB423, Mycobacterium tuberculosis RGTB327, Mycobacterium bovis BCG str. Mexico, Mycobacterium tuberculosis CTRI-2, Mycobacterium tuberculosis W-148, Mycobacterium tuberculosis CDC1551A, Mycobacterium tuberculosis SUMu012, Mycobacterium tuberculosis SUMu009, Mycobacterium tuberculosis SUMu008, Mycobacterium tuberculosis SUMu007, Mycobacterium tuberculosis SUMu006, Mycobacterium tuberculosis SUMu005, Mycobacterium tuberculosis SUMu004, Mycobacterium tuberculosis SUMu003, Mycobacterium tuberculosis SUMu002, Mycobacterium tuberculosis H37Ra, Mycobacterium caprae, Mycobacterium tuberculosis str. Kurono, Mycobacterium tuberculosis 49-02, Mycobacterium tuberculosis 7199-99, Mycobacterium canettii CIPT 140070008, Mycobacterium tuberculosis UT205, Mycobacterium tuberculosis NCGM2209, Mycobacterium bovis BCG str. Moreau RDJ, Mycobacterium bovis BCG str. Tokyo 172, Mycobacterium bovis BCG str. Pasteur 1173P2 Bacteria UP000001584 UP000001419, UP000025441, UP000036056, UP000065426, UP000029480, UP000031913, UP000031527, UP000027960, UP000027713, UP000027672, UP000028283, UP000028354, UP000027753, UP000027883, UP000027870, UP000027857, UP000027761, UP000027655, UP000027927, UP000027896, UP000027716, UP000027833, UP000027705, UP000027684, UP000027875, UP000027858, UP000027913, UP000027732, UP000027628, UP000027733, UP000027851, UP000027721, UP000027860, UP000027862, UP000027932, UP000027741, UP000027811, UP000027723, UP000027881, UP000027678, UP000027804, UP000027766, UP000027878, UP000027652, UP000027823, UP000027765, UP000027849, UP000027928, UP000027651, UP000027754, UP000027736, UP000027831, UP000027735, UP000027944, UP000027760, UP000027131, UP000026413, UP000026555, UP000025603, UP000025287, UP000026203, UP000025600, UP000026388, UP000025722, UP000025766, UP000025399, UP000026411, UP000026013, UP000025738, UP000025943, UP000026602, UP000025989, UP000026553, UP000026277, UP000025862, UP000026152, UP000026444, UP000025479, UP000025563, UP000026028, UP000026642, UP000025779, UP000026790, UP000026771, UP000025812, UP000025486, UP000025555, UP000026495, UP000026441, UP000026352, UP000026603, UP000025903, UP000025575, UP000025341, UP000026846, UP000026519, UP000026022, UP000025666, UP000026737, UP000025495, UP000025951, UP000026631, UP000026000, UP000026123, UP000025584, UP000025927, UP000025467, UP000025262, UP000026086, UP000026354, UP000025803, UP000026297, UP000025283, UP000026163, UP000025410, UP000025549, UP000026818, UP000025471, UP000026434, UP000026053, UP000025834, UP000026489, UP000026252, UP000026290, UP000025371, UP000026693, UP000026055, UP000025540, UP000026637, UP000026439, UP000025967, UP000026479, UP000025368, UP000025375, UP000026842, UP000025271, UP000025306, UP000025602, UP000026546, UP000026554, UP000025987, UP000026454, UP000025663, UP000026752, UP000025948, UP000025260, UP000026422, UP000026585, UP000026333, UP000026549, UP000025628, UP000026096, UP000026323, UP000026207, UP000026539, UP000025488, UP000026008, UP000026708, UP000026217, UP000026020, UP000025676, UP000025670, UP000026358, UP000026150, UP000025856, UP000026045, UP000026852, UP000025828, UP000026552, UP000025276, UP000025799, UP000026423, UP000025993, UP000026792, UP000026250, UP000026753, UP000026787, UP000026284, UP000026110, UP000026605, UP000026289, UP000026686, UP000025629, UP000026785, UP000025765, UP000026461, UP000026417, UP000025859, UP000026299, UP000025830, UP000025621, UP000026812, UP000026426, UP000025850, UP000025863, UP000026281, UP000025659, UP000025611, UP000026522, UP000026080, UP000025848, UP000026392, UP000026527, UP000026436, UP000025681, UP000026500, UP000025841, UP000025809, UP000026720, UP000026474, UP000026538, UP000026597, UP000026609, UP000026054, UP000025985, UP000025775, UP000026459, UP000025594, UP000025543, UP000026762, UP000025873, UP000026081, UP000026133, UP000026317, UP000025534, UP000026242, UP000026378, UP000025500, UP000025451, UP000025277, UP000026627, UP000026340, UP000026563, UP000025588, UP000025651, UP000026688, UP000025700, UP000025434, UP000025359, UP000026383, UP000026285, UP000025366, UP000026339, UP000026099, UP000026107, UP000053704, UP000025323, UP000053865, UP000025301, UP000025808, UP000026854, UP000026345, UP000026715, UP000025973, UP000025730, UP000025644, UP000026332, UP000026645, UP000026451, UP000026599, UP000026542, UP000026371, UP000026741, UP000026044, UP000025840, UP000026809, UP000026025, UP000025904, UP000025550, UP000026614, UP000026401, UP000026246, UP000025769, UP000026643, UP000026779, UP000026090, UP000026314, UP000025414, UP000026121, UP000026526, UP000026335, UP000026685, UP000025827, UP000025908, UP000025546, UP000026721, UP000025556, UP000026224, UP000026199, UP000025740, UP000025855, UP000025529, UP000026700, UP000025705, UP000025314, UP000025455, UP000026781, UP000026007, UP000026776, UP000025656, UP000025573, UP000025624, UP000026514, UP000025312, UP000026492, UP000026195, UP000025290, UP000026186, UP000026701, UP000025650, UP000026777, UP000026154, UP000026476, UP000025695, UP000025990, UP000025464, UP000026707, UP000026268, UP000025750, UP000026001, UP000026184, UP000025988, UP000026311, UP000026853, UP000025480, UP000026117, UP000025489, UP000026543, UP000025949, UP000025938, UP000026419, UP000026343, UP000026523, UP000026821, UP000026106, UP000026172, UP000025981, UP000025430, UP000025735, UP000025677, UP000026456, UP000026254, UP000026156, UP000026547, UP000026744, UP000025284, UP000026145, UP000025426, UP000026799, UP000026568, UP000025315, UP000026548, UP000026512, UP000025269, UP000025392, UP000026132, UP000026264, UP000026825, UP000026350, UP000025429, UP000026493, UP000026462, UP000026524, UP000025369, UP000026082, UP000026405, UP000025394, UP000025921, UP000026251, UP000026566, UP000025572, UP000026832, UP000026711, UP000025690, UP000026404, UP000025632, UP000026608, UP000025424, UP000025731, UP000025998, UP000026469, UP000026273, UP000025983, UP000026473, UP000026703, UP000025361, UP000026213, UP000025897, UP000025484, UP000026349, UP000026664, UP000026774, UP000026475, UP000025944, UP000026424, UP000025902, UP000026458, UP000025745, UP000026403, UP000026669, UP000025891, UP000025317, UP000026591, UP000026271, UP000025968, UP000025367, UP000026651, UP000025868, UP000026425, UP000025521, UP000025882, UP000025291, UP000025530, UP000025336, UP000026300, UP000026816, UP000026118, UP000025370, UP000025558, UP000026085, UP000026515, UP000026671, UP000026237, UP000026569, UP000026433, UP000026244, UP000026077, UP000026033, UP000026263, UP000026200, UP000025979, UP000025707, UP000025411, UP000026756, UP000026303, UP000025330, UP000026278, UP000025513, UP000025665, UP000025514, UP000026046, UP000026037, UP000026727, UP000025708, UP000025374, UP000025281, UP000025918, UP000026806, UP000026141, UP000025466, UP000026353, UP000026626, UP000026607, UP000026270, UP000026387, UP000026695, UP000025851, UP000026447, UP000026457, UP000025727, UP000025831, UP000025713, UP000026800, UP000025835, UP000025373, UP000026280, UP000025388, UP000025687, UP000026291, UP000025710, UP000025634, UP000026355, UP000025895, UP000026228, UP000026843, UP000026835, UP000025881, UP000026657, UP000026124, UP000025719, UP000026749, UP000025888, UP000025797, UP000025391, UP000025613, UP000025437, UP000025970, UP000025379, UP000026692, UP000026617, UP000025699, UP000025905, UP000025955, UP000026192, UP000025932, UP000025331, UP000026215, UP000026820, UP000025686, UP000025703, UP000025617, UP000026468, UP000026675, UP000026034, UP000026400, UP000025913, UP000026653, UP000026101, UP000025792, UP000025914, UP000026534, UP000026191, UP000025417, UP000025531, UP000025593, UP000025819, UP000025380, UP000025924, UP000026089, UP000026006, UP000025528, UP000025580, UP000026641, UP000025280, UP000026164, UP000026706, UP000027555, UP000025630, UP000025991, UP000026687, UP000026336, UP000026410, UP000026175, UP000025805, UP000026632, UP000025400, UP000026788, UP000027502, UP000026151, UP000025657, UP000026041, UP000025810, UP000026308, UP000025734, UP000026847, UP000026797, UP000025461, UP000025662, UP000025502, UP000026760, UP000025289, UP000025641, UP000026722, UP000026729, UP000026065, UP000025340, UP000027539, UP000026380, UP000026256, UP000026556, UP000025320, UP000025519, UP000026712, UP000025972, UP000025547, UP000025778, UP000026414, UP000025711, UP000026679, UP000025789, UP000025849, UP000026446, UP000027496, UP000026416, UP000025263, UP000025896, UP000025387, UP000025781, UP000026294, UP000026415, UP000025385, UP000027580, UP000025365, UP000026558, UP000026320, UP000026463, UP000025846, UP000025822, UP000026143, UP000025865, UP000026545, UP000025992, UP000026601, UP000025386, UP000025963, UP000026612, UP000026113, UP000026550, UP000026024, UP000026286, UP000026580, UP000025933, UP000026606, UP000025616, UP000025292, UP000025930, UP000025614, UP000025342, UP000025562, UP000026570, UP000025920, UP000026770, UP000026791, UP000027562, UP000026301, UP000026801, UP000026633, UP000026002, UP000026265, UP000026031, UP000026140, UP000026377, UP000025706, UP000025952, UP000026851, UP000025733, UP000026666, UP000026021, UP000026236, UP000025889, UP000026067, UP000025934, UP000026206, UP000025984, UP000025432, UP000025702, UP000026149, UP000025376, UP000025294, UP000025420, UP000025619, UP000026587, UP000025459, UP000026216, UP000026837, UP000026026, UP000026240, UP000025937, UP000025804, UP000026049, UP000025559, UP000026794, UP000026153, UP000025402, UP000025443, UP000026047, UP000025774, UP000026134, UP000025922, UP000025996, UP000025821, UP000026391, UP000025583, UP000026683, UP000026331, UP000026860, UP000026535, UP000025696, UP000025311, UP000026313, UP000025477, UP000025507, UP000026327, UP000026368, UP000026127, UP000026723, UP000026160, UP000025322, UP000025682, UP000026745, UP000026718, UP000026310, UP000025282, UP000025754, UP000026769, UP000026396, UP000026575, UP000025832, UP000025568, UP000026162, UP000026074, UP000026115, UP000026157, UP000026576, UP000026078, UP000025473, UP000025515, UP000025953, UP000025729, UP000025833, UP000025345, UP000026824, UP000025737, UP000026241, UP000026726, UP000025503, UP000025807, UP000026830, UP000025456, UP000025791, UP000026629, UP000025597, UP000025640, UP000025567, UP000025672, UP000026088, UP000025422, UP000025793, UP000025759, UP000026386, UP000026775, UP000026100, UP000025551, UP000025826, UP000025427, UP000025884, UP000025907, UP000025552, UP000025586, UP000025397, UP000026541, UP000025506, UP000026849, UP000026713, UP000025956, UP000026656, UP000026518, UP000025601, UP000026208, UP000025537, UP000025885, UP000025355, UP000026616, UP000026610, UP000025783, UP000025854, UP000026409, UP000026158, UP000025974, UP000026746, UP000025728, UP000025898, UP000025296, UP000026105, UP000025453, UP000025557, UP000025478, UP000026828, UP000026315, UP000026767, UP000026363, UP000026174, UP000026307, UP000026757, UP000025578, UP000026407, UP000026490, UP000026472, UP000026780, UP000026438, UP000026043, UP000026430, UP000026293, UP000025869, UP000026537, UP000026644, UP000025946, UP000026369, UP000026764, UP000026093, UP000025298, UP000025837, UP000026071, UP000025338, UP000025925, UP000025267, UP000026329, UP000026634, UP000025782, UP000026180, UP000025526, UP000025454, UP000026598, UP000025352, UP000026011, UP000025720, UP000025899, UP000026579, UP000026178, UP000025536, UP000026583, UP000026122, UP000025364, UP000025570, UP000026137, UP000026356, UP000026102, UP000025487, UP000026367, UP000025977, UP000026740, UP000026561, UP000026221, UP000026194, UP000026636, UP000026039, UP000025308, UP000026375, UP000026755, UP000025285, UP000025718, UP000026743, UP000026306, UP000026032, UP000025741, UP000025836, UP000026381, UP000025966, UP000026364, UP000026267, UP000026590, UP000026494, UP000025879, UP000026169, UP000026167, UP000025326, UP000026844, UP000025618, UP000026466, UP000025321, UP000025950, UP000025474, UP000026322, UP000026648, 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KBD73692.1, KBD71217.1, KBD65374.1, KBD63099.1, KBD59627.1, KBD54434.1, KBD51440.1, KBD46675.1, KBD45186.1, KBD39436.1, KBD36473.1, KBD31854.1, KBD26534.1, KBD23000.1, KBD18375.1, KBD15792.1, KBD11743.1, KBD07011.1, KBD04472.1, KBC99426.1, KBC95283.1, KBC91246.1, KBC88037.1, KBC83128.1, KBC79989.1, KBC75561.1, KBC69746.1, KBC68857.1, KBC64077.1, KBC59687.1, KBC59128.1, KBC50862.1, KBC47342.1, KBC44648.1, KBC39143.1, KBC35701.1, KBC32801.1, KBC26983.1, KBC22929.1, KBC20292.1, KBC16137.1, KBC10068.1, KBC09054.1, KBC02718.1, KBB99603.1, KBB95143.1, KBB89365.1, KBB88044.1, KBB83376.1, KBB79936.1, KBB74688.1, KBB71770.1, KBB67140.1, KBB63681.1, KBB59721.1, KBB54937.1, KBB51824.1, KBB48219.1, KBB43507.1, KBB38877.1, KBB35176.1, KBB31599.1, KBB27787.1, KBB23688.1, KBB21196.1, KBB15476.1, KBB11143.1, KBB07581.1, KBB02025.1, KBA99889.1, KBA96942.1, KBA91256.1, KBA87725.1, KBA81728.1, KBA79297.1, KBA76055.1, KBA72884.1, KBA67150.1, KBA65694.1, KBA59723.1, KBA56233.1, KBA52026.1, KBA51314.1, KBA49597.1, KBA39582.1, KBA38351.1, KBA36852.1, KBA29744.1, KBA26301.1, KBA23974.1, KBA15409.1, KBA14977.1, KBA09078.1, KBA04701.1, KBA02193.1, KBA01118.1, KAZ93726.1, KAZ92706.1, KAZ87644.1, KAZ82489.1, KAZ79237.1, KAZ71142.1, KAZ70331.1, KAZ64106.1, KAZ60783.1, KAZ58967.1, KAZ55758.1, KAZ49384.1, KAZ47155.1, KAZ43824.1, KAZ39026.1, KAZ30267.1, KAZ26829.1, KAZ26294.1, KAZ20813.1, KAZ13624.1, KAZ12857.1, KAZ10076.1, KAZ06317.1, KAZ03324.1, KAY96364.1, KAY92471.1, KAY90292.1, KAY88306.1, KAY81770.1, KAY77455.1, KAY71992.1, KAY69531.1, KAY66538.1, KAY60607.1, KAY56319.1, KAY55101.1, KAY49350.1, KAY40110.1, KAY38006.1, KAY37524.1, KAY33687.1, KAY33390.1, KAY22462.1, KAY21108.1, KAY20220.1, KAY13923.1, KAY07972.1, KAY05876.1, KAX99052.1, KAX95495.1, KAX93202.1, KAX92739.1, KAX83517.1, KAX83004.1, KAX82644.1, KAX75497.1, KAX68246.1, KAX67753.1, KAX62130.1, KAX60704.1, KAX54204.1, KAX52416.1, KAX44585.1, KAX41210.1, KAX38907.1, KAX33442.1, KAX33273.1, KAX28418.1, KAX20408.1, KAX19093.1, KAX16974.1, KAX12049.1, KAX10385.1, KAX03649.1, KAX00967.1, KAW92731.1, KAW88476.1, KAW88025.1, KAW78737.1, KAW75930.1, KAW75529.1, KAW66344.1, KAW60981.1, KAW60420.1, KAW57347.1, KAW53988.1, KAW51482.1, KAW45101.1, KAW42288.1, KAW38863.1, KAW36936.1, KAW30328.1, KAW22972.1, KAW19544.1, KAW14911.1, KAW10765.1, KAW05949.1, KAW04338.1, KAV99134.1, KAV94886.1, KAV91676.1, KAV86466.1, KAV82847.1, KAV81359.1, KAV74873.1, KAV71162.1, KAV66659.1, KAV62415.1, KAV56664.1, KAV55758.1, KAV51517.1, KAV46764.1, KAV37021.1, KAV31588.1, KAV27332.1, KAV22894.1, KAV17265.1, KAV11723.1, KAV08631.1, KAV02743.1, KAU99426.1, KAU96460.1, KAU90603.1, KAU86955.1, KAU82116.1, KAU74322.1, KAU72565.1, KAU66599.1, KAU63331.1, KAU58877.1, KAU53105.1, KAU50076.1, KAU38155.1, KAU36981.1, KAU26245.1, KAU23557.1, KAU18170.1, KAU15147.1, KAU07501.1, KAU06201.1, KAU03409.1, KAU01621.1, KAT96224.1, KAT90501.1, KAT87510.1, KAT82481.1, KAT80839.1, KAT72978.1, KAT70178.1, KAT69461.1, KAT59422.1, KAT58043.1, KAT54662.1, KAT50762.1, KAT43594.1, KAT39350.1, KAT38813.1, KAT36360.1, KAT27878.1, KAT26789.1, KAT22484.1, KAT20081.1, KAT15078.1, KAT10511.1, KAT07265.1, KAT01423.1, KAS97960.1, KAS92725.1, KAS88194.1, KAS87598.1, KAS84663.1, KAS79826.1, KAS76104.1, KAS69023.1, KAS68099.1, KAS64949.1, KAS59549.1, KAS54438.1, KAS51792.1, KAS48397.1, KAS41320.1, KAS40473.1, KAS39411.1, KAS30891.1, KAS28475.1, KAS27134.1, KAS18961.1, KAS15870.1, KAS10838.1, KAS09625.1, KAS04906.1, KAR99489.1, KAR95278.1, KAR91687.1, KAR87778.1, KAR82463.1, KAR81489.1, KAR79892.1, KAR71398.1, KAR69435.1, KAR64370.1, KAR59417.1, KAR58247.1, KAR52992.1, KAR47363.1, KAR46052.1, KAR41175.1, KAR36616.1, KAR30643.1, KAR29822.1, KAR22870.1, KAR19664.1, KAR15570.1, KAR10844.1, KAR06047.1, KAR02409.1, KAQ97406.1, KAQ94456.1, KAQ90355.1, KAQ85984.1, KAQ82697.1, KAQ79540.1, KAQ73434.1, KAQ70373.1, KAQ68902.1, KAQ62155.1, KAQ58099.1, KAQ57330.1, KAQ49840.1, KAQ46255.1, KAQ39698.1, KAQ38754.1, KAQ33888.1, KAQ31595.1, KAQ29610.1, KAQ22819.1, KAQ19014.1, KAQ14117.1, KAQ11263.1, KAQ08880.1, KAQ06193.1, KAP99831.1, KAP97153.1, KAP91319.1, KAP86572.1, KAP82880.1, KAP77964.1, KAP75998.1, KAP71380.1, KAP68060.1, KAP62863.1, KAP58465.1, KAP55448.1, KAP51152.1, KAP46944.1, KAP43834.1, KAP39027.1, KAP37108.1, KAP31919.1, KAP28946.1, KAP24371.1, KAP21195.1, KAP15099.1, KAP13845.1, KAP06932.1, KAP01912.1, KAP00101.1, KAO92049.1, KAO91621.1, KAO89476.1, KAO84249.1, KAO79295.1, KAO77905.1, KAO71124.1, KAO67637.1, KAO64980.1, KAO58500.1, KAO56696.1, KAO52208.1, KAO47128.1, KAO43452.1, KAO39820.1, KAO34621.1, KAO32597.1, KAO29112.1, KAO22386.1, KAO18161.1, KAO15888.1, KAO11293.1, KAO08108.1, KAO03130.1, KAO02108.1, KAN99956.1, KAN90780.1, KAN85793.1, KAN82536.1, KAN80513.1, KAN77321.1, KAN70165.1, KAN67855.1, KAN63028.1, KAN57439.1, KAN54504.1, KAN51016.1, KAN47391.1, KAN46550.1, KAN39186.1, KAN33589.1, KAN32944.1, KAN28735.1, KAN23422.1, KAN18059.1, KAN12883.1, KAN12463.1, KAN05144.1, KAN01771.1, KAN00701.1, KAM94452.1, KAM91775.1, KAM85997.1, KAM84312.1, KAM79374.1, KAM74428.1, KAM72369.1, KAM65883.1, KAM64226.1, KAM59500.1, KAM54040.1, KAM52687.1, KAM47171.1, KAM42150.1, KAM38778.1, KAM35895.1, KAM29749.1, KAM25629.1, KAM20719.1, KAM19016.1, KAM13211.1, KAM12701.1, KAM07308.1, KAM02781.1, KAL99773.1, KAL95935.1, KAL91789.1, KAL88794.1, KAL83608.1, KAL80172.1, KAL77374.1, KAL71545.1, KAL66235.1, KAL63163.1, KAL59490.1, KAL56120.1, KAL54740.1, KAL49001.1, KAL44863.1, KAL38519.1, KAL35799.1, KAL29865.1, KAL27199.1, KAL22836.1, KAL19774.1, KAL14087.1, KAL10850.1, KAL07860.1, KAL00282.1, KAK92085.1, KAK28636.1, AHM06116.1, AHJ53524.1, AHJ49386.1, AHJ45237.1, AHJ41086.1, EUB01739.1, EUA96951.1, EUA94797.1, ESK77582.1, ESK74677.1, EQM24300.1, EQM21991.1, EPZ63323.1, AGQ33963.1, AGL98872.1, AGL29851.1, AGJ66424.1, AFN48278.1, AFM47806.1, AFE11753.1, AFE15401.1, AET17721.1, AEM98869.1, AEJ49228.1, AEJ45586.1, AEB02556.1, EGE49182.1, EGB30157.1, EFP56189.1, EFP44675.1, EFP40022.1, EFP36092.1, EFP32182.1, EFP28317.1, EFP24740.1, EFP20925.1, EFP16563.1, EFI28987.1, EFD76069.1, EFD72061.1, EFD60468.1, EFD52135.1, EFD42017.1, EFD16122.1, EFD11962.1, ACT23453.1, ABR04771.1, ABQ72149.1, EBA40946.1 NP_854094.1, NP_214937.1, WP_003900143.1 P66912, A1KFP5, C1AK99, A5TZE9, P9WG78, P9WG79 THIC_MYCBO, THIC_MYCBP, THIC_MYCBT, THIC_MYCTA, THIC_MYCTO, THIC_MYCTU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6101472, 32194, 3689734, 7413578, 6079380, 3477024, 538722, 6118439, 6074345, 6070188, 6097326, 2098735, 6113969, 4060852, 7603833, 108273 fig|1205675.3.peg.448, fig|1306400.3.peg.480, fig|1765.10.peg.4265, fig|757420.3.peg.462, fig|911237.3.peg.158, fig|478434.4.peg.461, fig|1806.1.peg.3166, fig|998091.3.peg.2788, fig|675517.3.peg.939, fig|410289.13.peg.454, fig|555461.3.peg.338, fig|1279011.3.peg.2984, fig|882100.3.peg.456, fig|747367.3.peg.456, fig|515616.3.peg.97, fig|757421.3.peg.461, fig|663886.3.peg.290, fig|998089.3.peg.2082, fig|478433.3.peg.291, fig|675514.3.peg.486, fig|1773.31.peg.688, fig|757417.4.peg.463, fig|419947.3.peg.423, fig|520140.3.peg.498, fig|1274431.3.peg.1025, fig|757418.3.peg.462, fig|443150.4.peg.458, fig|83332.1.peg.423, fig|611303.3.peg.250, fig|659019.3.peg.94, fig|675518.3.peg.964, fig|1240677.3.peg.103, fig|1206780.3.peg.469, fig|882098.3.peg.457, fig|675520.3.peg.170, fig|652616.3.peg.472, fig|520141.3.peg.51, fig|611304.3.peg.3229, fig|443149.4.peg.473, fig|707235.4.peg.458, fig|675519.3.peg.964, fig|747368.3.peg.457, fig|757419.3.peg.461, fig|1078763.3.peg.886, fig|336982.3.peg.438, fig|1126682.4.peg.1031, fig|998090.3.peg.1901, fig|675515.3.peg.643, fig|1310115.3.peg.475, fig|707237.3.peg.316, fig|164513.4.peg.3312, fig|233413.1.peg.424, fig|478435.3.peg.4195, fig|1091501.3.peg.550, fig|675516.3.peg.964, fig|395095.3.peg.706, fig|717522.6.peg.465, fig|757422.3.peg.461, fig|663887.3.peg.241, fig|1322343.3.peg.1649, fig|1126683.4.peg.1663, fig|675523.3.peg.477, fig|611302.3.peg.903, fig|1246121.3.peg.456, fig|675513.3.peg.969, fig|561275.4.peg.469, fig|1138877.3.peg.470, fig|83331.22.peg.472, fig|998092.3.peg.2289, fig|1246634.3.peg.446, fig|747369.3.peg.459, fig|882099.3.peg.456 544 547 yes 437802 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 29543, 338966 Pelobacter propionicus, Pelobacter propionicus DSM 2379 Bacteria UP000006732 500056733, 118503926 ABL00409.1 WP_011736650.1 fig|338966.5.peg.2764 432 435 yes 437803 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 360104 Campylobacter concisus 13826 Bacteria UP000001121 112800254 EAT97598.1 fig|360104.4.peg.727 431 431 yes 437804 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 823, 435591 Parabacteroides distasonis, Parabacteroides distasonis ATCC 8503 Bacteria UP000000566 500654386, 149936128 ABR42825.1 WP_011966300.1 fig|435591.10.peg.1003 565 565 yes 437805 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 273063, 111955 Sulfolobus tokodaii str. 7, Sulfolobus tokodaii Archaea UP000001015 15922177, 499288642, 29337114, 15622966 NP_377846.1, WP_010979932.1 Q96ZH0 THIC_SULTO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 138316, 373244 fig|273063.1.peg.2014 429 429 yes 437806 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 243232, 2190 Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii Archaea UP000000805 UP000000805 161579523, 499172952, 24638455 NP_248020.2, WP_010870539.1 Q58432 THIC_METJA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 9617 fig|243232.1.peg.1057 426 426 yes 437807 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 47678, 411901, 1263037 Bacteroides caccae, Bacteroides caccae ATCC 43185, Bacteroides caccae CAG:21 Bacteria, Environmental samples UP000003325, UP000017990 491927158, 149131269, 524205879 EDM22475.1 WP_005676167.1 fig|411901.7.peg.800 562 562 yes 437808 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 391596 Pedobacter sp. BAL39 Bacteria UP000003664 495516159, 149231395 EDM36774.1 WP_008240804.1 fig|391596.3.peg.1985 627 627 yes 437809 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28105, 366394 Sinorhizobium medicae WSM419 Bacteria UP000001108 500666866, 150376316, 150030863 ABR62979.1 WP_011969801.1, YP_001312912.1 7034077 fig|366394.8.peg.631 597 610 yes 437810 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 87883, 985079, 985078, 513051, 395019 Burkholderia multivorans, Burkholderia multivorans ATCC BAA-247, Burkholderia multivorans CF2, Burkholderia multivorans CGD1, Burkholderia multivorans ATCC 17616 Bacteria UP000066418, UP000032885, UP000006608, UP000005493, UP000007064 493445803, 773023150, 686823804, 685688904, 400232138, 400221317, 221166170, 160342680, 238687010, 189334033 AJY17487.1, KGC03046.1, AIO76020.1, EJO61776.1, EJO51781.1, EED98643.1, ABX15766.1 WP_006401164.1 A9ACX9 THIC_BURM1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7115384, 6427874, 6413636, 6420991 fig|395019.3.peg.2193, fig|985078.3.peg.543, fig|985079.3.peg.5509, fig|513051.3.peg.4413 642 643 yes 437811 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 391613 Roseovarius sp. TM1035 Bacteria UP000005610 495555671, 149144988 EDM33017.1 WP_008280250.1 fig|391613.3.peg.1193 597 600 yes 437812 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1219, 93059 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9211 Bacteria UP000000788 501151426, 159889453, 238687126 ABX09667.1 WP_012196287.1 A9BD54 THIC_PROM4 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1193978 fig|93059.3.peg.1605 456 459 yes 437813 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 161528 Erythrobacter sp. SD-21 Bacteria UP000005498 493887018, 148830778 EDL49213.1 WP_006833135.1 fig|161528.3.peg.1376 632 636 yes 437814 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 580165, 315749 Bacillus cytotoxicus, Bacillus cytotoxicus NVH 391-98 Bacteria UP000053965, UP000002300 501044371, 152026183, 189030269 ABS23953.1 WP_012096209.1 A7GUZ5 THIC_BACCN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3424576 fig|315749.4.peg.3835 586 586 yes 437815 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 42879, 419665 Methanococcus aeolicus, Methanococcus aeolicus Nankai-3 Archaea UP000001106 500681080, 150013245, 166228037 ABR55696.1 WP_011972828.1 A6UT74 THIC_META3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3687849 fig|419665.8.peg.108 426 426 yes 437816 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 62322, 693972, 693973, 399599 Shewanella baltica, Shewanella baltica OS625, Shewanella baltica OS678, Shewanella baltica OS195 Bacteria UP000004265, UP000007240, UP000000770 493005834, 353535331, 315267739, 160861073 EHC04894.1, ADT94592.1, ABX49607.1 WP_006086794.1 fig|693972.3.peg.3562, fig|693973.4.peg.2263, fig|399599.3.peg.2479 655 707 yes 437817 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86665, 272558 Bacillus halodurans, Bacillus halodurans C-125 Bacteria UP000001258 499200552, 20140836, 10174551 WP_010898092.1 Q9KBJ4 THIC_BACHD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 64514 fig|272558.1.peg.1933 595 595 yes 437818 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 39152, 426368 Methanococcus maripaludis, Methanococcus maripaludis C7 Archaea UP000002298 500697098, 150034139, 166228041 ABR66252.1 WP_011977562.1 A6VIH6 THIC_METM7 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3704898 fig|426368.9.peg.1197 426 426 yes 437819 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 50743 unidentified eubacterium SCB49 Environmental samples UP000003659 149357096 EDM45651.1 fig|50743.3.peg.407 626 630 yes 437820 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2173, 420247 Methanobrevibacter smithii, Methanobrevibacter smithii ATCC 35061 Archaea UP000001992 500588578, 148551721 ABQ86849.1 WP_011954021.1 A5UKX1 A5UKX1_METS3 fig|420247.6.peg.627 423 424 yes 437821 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 56, 448385 Sorangium cellulosum, Sorangium cellulosum 'So ce 56' Bacteria UP000002139 501193865, 161163108 WP_012236883.1 fig|448385.16.peg.4646, fig|448385.11.peg.3923 459 462 yes 437822 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 221822, 391619 Phaeobacter inhibens, Phaeobacter gallaeciensis BS107 Bacteria UP000002914 504692387, 398656668 AFO90634.1 WP_014879489.1 fig|391619.3.peg.3490 593 599 yes 437823 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 43687, 399549 Metallosphaera sedula, Metallosphaera sedula DSM 5348 Archaea UP000056255, UP000000242 676315432, 145701936 AIM27064.1, ABP95078.1 A0A088E3R1, A4YF76 A0A088E3R1_9CREN, A4YF76_METS5 fig|399549.6.peg.901 434 435 yes 437824 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2424, 381764 Fervidobacterium nodosum, Fervidobacterium nodosum Rt17-B1 Bacteria UP000002415 500776762, 154154033 ABS61265.1 WP_011994571.1 fig|381764.6.peg.1392 425 425 yes 437825 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 145262, 187420 Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus str. Delta H Archaea UP000005223 499179612, 2622663, 7388295 AAB86017.1 WP_010877152.1 O27586 THIC1_METTH Phosphomethylpyrimidine synthase 1 {ECO:0000255|HAMAP-Rule:MF_00089} 21511 fig|187420.1.peg.1511, fig|196600.1.peg.5607 433 433 yes 437826 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 110500, 370438 Pelotomaculum thermopropionicum, Pelotomaculum thermopropionicum SI Bacteria UP000054705, UP000006556 500956327, 189030277, 146273076 WP_012031815.1 A5D4K5 THIC_PELTS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5526887 fig|370438.3.peg.731 431 432 yes 437827 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2287, 273057 Sulfolobus solfataricus, Sulfolobus solfataricus P2 Archaea UP000001974 UP000033085, UP000001974 499225778, 13814529, 29337120 AAK41561.1 WP_010923318.1 Q97YJ8 THIC1_SULSO Phosphomethylpyrimidine synthase 1 {ECO:0000255|HAMAP-Rule:MF_00089} 106053 fig|273057.1.peg.1194 432 433 yes 437828 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 573, 1438787, 1328373, 1328372, 1250520, 1162296, 272620, 1432547 Klebsiella pneumoniae, Klebsiella pneumoniae MGH 64, Klebsiella pneumoniae MGH 39, Klebsiella pneumoniae MGH 36, Klebsiella pneumoniae RYC492, Klebsiella pneumoniae subsp. pneumoniae DSM 30104, Klebsiella pneumoniae subsp. pneumoniae MGH 78578, Klebsiella pneumoniae IS22 Bacteria UP000036212, UP000027159, UP000022914, UP000017441, UP000011913, UP000036622, UP000000265 491011588, 727668057, 673514091, 636354312, 583705209, 555143612, 459936368, 397741597, 150957705, 571216335, 166228036 KHF63285.1, KFJ78306.1, KDL31766.1, EWF67348.1, ESM86350.1, EMI00031.1, EJK88819.1, ABR79735.1 WP_004873297.1 A6TGQ1 THIC_KLEP7 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7444408, 3384853 fig|272620.3.peg.4398, fig|1279040.3.peg.4412, fig|1162296.3.peg.4943 626 631 yes 437829 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 666, 417398 Vibrio cholerae, Vibrio cholerae MZO-2 Bacteria UP000028983, UP000005847 445993266, 149739579 EDM53803.1 WP_000071121.1 fig|417398.15.peg.2813 639 645 yes 437830 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 94624, 340100 Bordetella petrii, Bordetella petrii DSM 12804 Bacteria UP000001225 501208491, 229558530, 163262732 WP_012251509.1 A9IFG8 THIC_BORPD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3493798 fig|340100.3.peg.4706 636 637 yes 437831 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 411489 Clostridium sp. L2-50 Bacteria UP000003352 495677366, 156864391 EDO57822.1 WP_008401945.1 fig|411489.7.peg.1687 435 436 yes 437832 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 632, 349746 Yersinia pestis, Yersinia pestis Angola Bacteria UP000000815 UP000031825, UP000031869 501185973, 755425640, 162352589 AJJ82216.1, ABX86537.1 WP_012229040.1 fig|349746.3.peg.3633 651 681 yes 437833 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1206780, 83331 Mycobacterium bovis BCG str. Korea 1168P, Mycobacterium tuberculosis CDC1551 Bacteria UP000011299, UP000025508 449030930, 13879941 AGE66357.1, AAK44661.1 P9WG78 THIC_MYCTO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} fig|1205675.3.peg.448, fig|1306400.3.peg.480, fig|1765.10.peg.4265, fig|757420.3.peg.462, fig|911237.3.peg.158, fig|478434.4.peg.461, fig|1806.1.peg.3166, fig|998091.3.peg.2788, fig|675517.3.peg.939, fig|410289.13.peg.454, fig|555461.3.peg.338, fig|1279011.3.peg.2984, fig|882100.3.peg.456, fig|747367.3.peg.456, fig|515616.3.peg.97, fig|757421.3.peg.461, fig|663886.3.peg.290, fig|998089.3.peg.2082, fig|478433.3.peg.291, fig|675514.3.peg.486, fig|1773.31.peg.688, fig|757417.4.peg.463, fig|419947.3.peg.423, fig|520140.3.peg.498, fig|1274431.3.peg.1025, fig|757418.3.peg.462, fig|443150.4.peg.458, fig|83332.1.peg.423, fig|611303.3.peg.250, fig|659019.3.peg.94, fig|675518.3.peg.964, fig|1240677.3.peg.103, fig|1206780.3.peg.469, fig|882098.3.peg.457, fig|675520.3.peg.170, fig|652616.3.peg.472, fig|520141.3.peg.51, fig|611304.3.peg.3229, fig|443149.4.peg.473, fig|707235.4.peg.458, fig|675519.3.peg.964, fig|747368.3.peg.457, fig|757419.3.peg.461, fig|1078763.3.peg.886, fig|336982.3.peg.438, fig|1126682.4.peg.1031, fig|998090.3.peg.1901, fig|675515.3.peg.643, fig|537209.3.peg.21, fig|1310115.3.peg.475, fig|707237.3.peg.316, fig|164513.4.peg.3312, fig|233413.1.peg.424, fig|478435.3.peg.4195, fig|1091501.3.peg.550, fig|675516.3.peg.964, fig|395095.3.peg.706, fig|717522.6.peg.465, fig|757422.3.peg.461, fig|663887.3.peg.241, fig|1322343.3.peg.1649, fig|1126683.4.peg.1663, fig|675523.3.peg.477, fig|611302.3.peg.903, fig|1246121.3.peg.456, fig|675513.3.peg.969, fig|561275.4.peg.469, fig|1138877.3.peg.470, fig|83331.22.peg.472, fig|998092.3.peg.2289, fig|1246634.3.peg.446, fig|747369.3.peg.459, fig|83331.1.peg.438, fig|882099.3.peg.456 547 549 yes 437834 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 41514 Salmonella enterica subsp. arizonae serovar 62:z4,z23:-- Bacteria UP000002084 160866696, 189030280 ABX23319.1 A9MHD6 THIC_SALAR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3351611 fig|41514.4.peg.3335 626 631 yes 437835 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 181663, 96561 Desulfococcus oleovorans, Desulfococcus oleovorans Hxd3 Bacteria UP000008561 501126786, 158511264, 238686893 ABW68231.1 WP_012175843.1 A8ZVP4 THIC_DESOH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7029474 fig|96561.3.peg.2421 426 426 yes 437836 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 331111 Escherichia coli, Escherichia coli E24377A Bacteria UP000036210, UP000031953 447199671, 157081295, 166987538 ABV21003.1 WP_001276927.1 A7ZUK9 THIC_ECO24 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3471488 fig|331111.12.peg.4749 626 631 yes 437837 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 290338 Citrobacter koseri ATCC BAA-895 Bacteria UP000008148 157084414, 166228028 ABV14092.1 A8AKS9 THIC_CITK8 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3404661 fig|290338.6.peg.2516 626 631 yes 437838 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1148, 1204343, 1080230, 1080229, 1080228, 1111708 Synechocystis sp. PCC 6803, Bacillus subtilis BEST7613, Synechocystis sp. PCC 6803 substr. PCC-P, Synechocystis sp. PCC 6803 substr. PCC-N, Synechocystis sp. PCC 6803 substr. GT-I, Synechocystis sp. PCC 6803 substr. Kazusa Bacteria UP000001425 UP000008187, UP000011218, UP000007107, UP000007108, UP000007109, UP000001425 499176297, 757301007, 756901267, 568760844, 451781979, 407960508, 359279261, 359276091, 359272921, 339274955, 3024729, 1208488 AJO05606.1, AJN19678.1, AHE23974.1, AGF52948.1 WP_010873884.1 Q55894 THIC_SYNY3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 12977 fig|1148.1.peg.2687, fig|227377.1.peg.577, fig|1293501.3.peg.1139, fig|1196327.3.peg.184, fig|1294266.3.peg.799 457 459 yes 437839 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 145262, 187420 Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus str. Delta H Archaea UP000005223 499179644, 2622698, 7388296 AAB86049.1 WP_010877184.1 O27617 THIC2_METTH Phosphomethylpyrimidine synthase 2 {ECO:0000255|HAMAP-Rule:MF_00089} 21543 fig|187420.1.peg.1543, fig|196600.1.peg.3381 424 424 yes 437840 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 391625 Plesiocystis pacifica SIR-1 Bacteria UP000005801 149818253 EDM77706.1 fig|391625.5.peg.4243 540 567 yes 437841 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 400668 Marinomonas sp. MWYL1 Bacteria UP000001113 150837338 ABR71314.1 fig|400668.6.peg.2432 640 680 yes 437842 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 316, 379731 Pseudomonas stutzeri, Pseudomonas stutzeri A1501 Bacteria UP000037382, UP000000233 500263940, 145572333, 166987542 ABP81439.1 WP_011914824.1 A4VR38 THIC_PSEU5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3561577 fig|379731.4.peg.3794 627 627 yes 437843 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1534, 431943, 583346 Clostridium kluyveri, Clostridium kluyveri DSM 555, Clostridium kluyveri NBRC 12016 Bacteria UP000002411, UP000007969 501050526, 146347282, 254784158, 219568716, 189030272 EDK33818.1 WP_012102171.1 B9E2H5, A5N937 THIC_CLOK1, THIC_CLOK5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3709992, 5861629 fig|583346.6.peg.1844, fig|431943.4.peg.1821 437 437 yes 437844 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1126, 1235808, 267872 Microcystis aeruginosa, Microcystis aeruginosa DIANCHI905, Microcystis aeruginosa PCC 7806 Bacteria UP000011202 488835718, 443330823, 159030373 ELS45513.1 WP_002748124.1 fig|1235808.3.peg.4389 457 460 yes 437845 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28151, 399741 Serratia proteamaculans, Serratia proteamaculans 568 Bacteria UP000007074 500839664, 157320297 ABV39394.1 WP_012004751.1 fig|399741.3.peg.311 633 647 yes 437846 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 375286 Janthinobacterium sp. Marseille Bacteria UP000006388 501026143, 151280152, 166228035 ABR88562.1 WP_012078249.1 A6SUX7 THIC_JANMA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3549264 fig|375286.6.peg.397 636 637 yes 437847 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 300, 399739 Pseudomonas mendocina, Pseudomonas mendocina ymp Bacteria UP000028008, UP000000229 500269935, 145573845, 166987541 ABP83377.1 WP_011920819.1 A4XPW1 THIC_PSEMY Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3613795 fig|399739.6.peg.595 627 627 yes 437848 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 208226, 293826 Alkaliphilus metalliredigens, Alkaliphilus metalliredigens QYMF Bacteria UP000001572 501012376, 149951785, 166987531 ABR50313.1 WP_012065261.1 A6TVU5 THIC_ALKMQ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6858614 fig|293826.4.peg.4064 437 437 yes 437849 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2284, 426118, 2287, 555311, 429572, 273057 Sulfolobus islandicus M.16.4, Sulfolobus solfataricus, Sulfolobus solfataricus 98/2, Sulfolobus islandicus L.S.2.15, Sulfolobus solfataricus P2 Archaea UP000001974 UP000001479, UP000033085, UP000001493, UP000001747, UP000001974 497678413, 238619404, 800908035, 800905344, 800902647, 261603230, 238380473, 227456059, 13815215, 259517502, 259517497, 29337119 AKA80216.1, AKA77526.1, AKA74830.1, ACX92833.1, ACR41561.1, ACP34746.1, AAK42135.1 WP_009992597.1, YP_002914229.1 Q97X14, C4KG47, C3MMC3, A0A0E3GVL4, D0KPS9 THIC2_SULSO, THIC_SULIK, THIC_SULIL Phosphomethylpyrimidine synthase 2 {ECO:0000255|HAMAP-Rule:MF_00089}, Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} A0A0E3GVL4_SULSF, D0KPS9_SULS9 7252979, 106627, 10497814, 7277863 fig|273057.1.peg.1768 432 433 yes 437850 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 288000 Bradyrhizobium sp. BTAi1 Bacteria UP000000246 500992609, 146409643, 166228015 ABQ38149.1 WP_012046098.1 A5EPQ5 THIC_BRASB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6837571 fig|288000.5.peg.6072 622 633 yes 437851 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2173, 420247 Methanobrevibacter smithii, Methanobrevibacter smithii ATCC 35061 Archaea UP000001992 500589423, 148552465 ABQ87593.1 WP_011954478.1 A5UN15 A5UN15_METS3 fig|420247.6.peg.1360 432 432 yes 437852 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 272631, 1769, 561304 Mycobacterium leprae TN, Mycobacterium leprae, Mycobacterium leprae Br4923 Bacteria UP000000806, UP000006900 15827068, 499210115, 254784167, 219932653, 13092616, 7388313, 4154058 NP_301331.1, WP_010907655.1 B8ZU90, Q9ZBL0 THIC_MYCLB, THIC_MYCLE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5832411, 81293 fig|272631.1.peg.203, fig|561304.4.peg.458 546 547 yes 437853 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 33996, 272568 Gluconacetobacter diazotrophicus, Gluconacetobacter diazotrophicus PAl 5 Bacteria UP000001176 501180033, 209531233, 161785013 ACI51170.1 WP_012223163.1 fig|272568.12.peg.610, fig|272568.11.peg.1389 614 626 yes 437854 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 522, 1464546, 1043206, 349163, 926570 Acidiphilium sp. JA12-A1, Acidiphilium sp. PM, Acidiphilium cryptum JF-5, Acidiphilium multivorum AIU301 Bacteria UP000027608, UP000004823, UP000000245, UP000032662 494663448, 636532975, 338209157, 146401656, 775293014, 325049931 KDM65468.1, EGO96946.1, ABQ30183.1 WP_007421392.1 fig|926570.3.peg.1296, fig|1043206.3.peg.90, fig|349163.14.peg.1456 603 606 yes 437855 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 351604, 351605 Geobacter uraniireducens, Geobacter uraniireducens Rf4 Bacteria UP000006695 500473814, 146399369 ABQ28002.1 WP_011940648.1 fig|351605.4.peg.3778 435 435 yes 437856 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 155978, 329726 Acaryochloris marina, Acaryochloris marina MBIC11017 Bacteria UP000000268 501113910, 158306381, 189030268 ABW27998.1 WP_012163431.1 B0CCG9 THIC_ACAM1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3461166 fig|329726.14.peg.2770 455 458 yes 437857 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 114615 Bradyrhizobium sp. ORS278 Bacteria UP000001994 500949461, 166228016, 146195357 WP_012029288.1 A4YZQ6 THIC_BRASO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3667685 fig|114615.3.peg.5492 622 633 yes 437858 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 391597 Limnobacter sp. MED105 Bacteria UP000010322 495525062, 149824675 EDM83891.1 WP_008249707.1 fig|391597.3.peg.1431 636 638 yes 437859 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 666, 417397 Vibrio cholerae, Vibrio cholerae 623-39 Bacteria UP000028983, UP000004113 445993259, 148875428 EDL73563.1 WP_000071114.1 fig|417397.11.peg.342 639 645 yes 437860 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 287, 381754 Pseudomonas aeruginosa, Pseudomonas aeruginosa PA7 Bacteria UP000065817, UP000001582 501025548, 150959425, 166228057 ABR81450.1 WP_012077657.1 A6VD86 THIC_PSEA7 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7068584 fig|381754.5.peg.5427 627 627 yes 437861 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 438753 Azorhizobium caulinodans ORS 571 Bacteria UP000000270 158331120 fig|438753.3.peg.2724 609 618 yes 437862 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 155864, 83334 Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 Bacteria UP000028484, UP000034479 12518923 AAG59191.1 Q8X6X9 THIC_ECO57 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 96386, 7328454, 5000775, 4962569, 5006794, 5013826, 4984144, 7566676, 4994088, 5015615, 4981037, 4947061, 10470842, 4956347, 4974716, 6017791 fig|155864.1.peg.4934 626 631 yes 437863 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 224324, 63363 Aquifex aeolicus VF5, Aquifex aeolicus Bacteria UP000000798 UP000000798 15606443, 499183221, 2983647, 7388305 AAC07214.1 NP_213823.1, WP_010880761.1 O67259 THIC_AQUAE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 25131 fig|224324.1.peg.838 452 457 yes 437864 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 271097, 425104 Shewanella sediminis, Shewanella sediminis HAW-EB3 Bacteria UP000002015 501092182, 157317524, 189030300 ABV36622.1 WP_012142357.1 A8FUU9 THIC_SHESH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3701082 fig|425104.7.peg.2141, fig|425104.3.peg.1776 639 652 yes 437865 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 411485 Faecalibacterium prausnitzii M21/2 Bacteria UP000005945 158445745 EDP22748.1 447 454 yes 437866 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 197, 360109 Campylobacter jejuni, Campylobacter jejuni subsp. doylei 269.97 Bacteria UP000065538, UP000002302 500763790, 152939880, 166228026 ABS44621.1 WP_011990556.1 A7H4T0 THIC_CAMJD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7009769 fig|360109.10.peg.1472 429 430 yes 437867 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 76517, 360107 Campylobacter hominis, Campylobacter hominis ATCC BAA-381 Bacteria UP000002407 501057092, 153804035, 166228025 ABS51042.1 WP_012108540.1 A7I162 THIC_CAMHC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3539686 fig|360107.7.peg.649, fig|360107.5.peg.663 447 449 yes 437868 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 32051 Synechococcus sp. WH 7803 Bacteria UP000001566 500452525, 166228063, 147847065 WP_011932122.1 A5GI51 THIC_SYNPW Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3340742 fig|32051.4.peg.191 465 467 yes 437869 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 461876, 350688 Alkaliphilus oremlandii, Alkaliphilus oremlandii OhILAs Bacteria UP000000269 501108998, 158140006, 166987532 ABW18318.1 WP_012158630.1 A8MEI9 THIC_ALKOO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6975657 fig|350688.3.peg.748 437 437 yes 437870 phosphomethylpyrimidine synthase, chloroplastic 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) CFM 3702 Arabidopsis thaliana Plants UP000006548 UP000006548 334184567, 30684307, 15227584, 757301006, 756901266, 568760843, 330253189, 330253188, 330253187, 29713445, 22136156, 20260180, 3582335, 75220243 AJO05605.1, AJN19677.1, AHE23973.1, AEC08283.1, AEC08282.1, AEC08281.1, AAO99665.1, AAM91156.1, AAM12988.1, AAC35232.1 NP_001189634.1, NP_850135.1, NP_180524.1 O82392 THIC_ARATH Phosphomethylpyrimidine synthase, chloroplastic 10089964 556 644 4N7Q, 4S29, 4S28, 4S27, 4S26, 4S25 4.1.99.17 yes 437871 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1491, 441771, 413999, 1302427, 441770 Clostridium botulinum, Clostridium botulinum A str. Hall, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum CFSAN002369, Clostridium botulinum A str. ATCC 19397 Bacteria UP000001986 UP000030128, UP000002409, UP000015063, UP000006379 500994496, 153937317, 148380866, 526255127, 152933231, 152930312, 166987535, 166987534, 148290350 EPS47869.1, ABS38730.1, ABS35812.1 WP_012047970.1, YP_001388642.1, YP_001255407.1 A7FXG9, A5I5Z5 THIC_CLOB1, THIC_CLOBH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3740614, 3675390, 3744239 fig|441771.6.peg.2732, fig|441770.6.peg.2784, fig|413999.7.peg.2891, fig|441770.4.peg.2690, fig|413999.4.peg.2787, fig|441771.4.peg.2628 437 437 yes 437872 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 160233, 453591 Ignicoccus hospitalis, Ignicoccus hospitalis KIN4/I Archaea UP000000262 500798707, 156936899, 156565883, 166228034 ABU81288.1 WP_011998140.1, YP_001434695.1 A8A8N6 THIC_IGNH4 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3778064 fig|453591.8.peg.101 437 439 yes 437873 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 236100, 443152 Marinobacter algicola, Marinobacter algicola DG893 Bacteria UP000005856 494268338, 149357766 EDM46261.1 WP_007155215.1 fig|443152.3.peg.3571 622 625 yes 437874 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 43661, 314608 Shewanella benthica, Shewanella benthica KT99 Bacteria UP000005839 491644232, 161328327 EDP99487.1 WP_005501759.1 fig|314608.4.peg.3346 647 658 yes 437875 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28197, 1447263, 1447262, 1447261, 1447256, 1036172, 888827, 367737 Arcobacter butzleri, Arcobacter butzleri L355, Arcobacter butzleri L354, Arcobacter butzleri L353, Arcobacter butzleri L348, Arcobacter butzleri 7h1h, Arcobacter butzleri JV22, Arcobacter butzleri RM4018 Bacteria UP000035154, UP000035396, UP000035558, UP000035514, UP000015083, UP000002981, UP000001136 490645171, 822323831, 822322593, 822319302, 822307141, 526271360, 315480287, 157698249 KLE11493.1, KLE10323.1, KLE07208.1, KLD95846.1, AGR76458.1, EFU70954.1, ABV66409.1 WP_004510166.1 fig|888827.3.peg.1398, fig|367737.4.peg.124, fig|1036172.3.peg.160 448 450 yes 437876 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 272562, 1488, 991791, 863638 Clostridium acetobutylicum ATCC 824, Clostridium acetobutylicum, Clostridium acetobutylicum DSM 1731, Clostridium acetobutylicum EA 2018 Bacteria UP000000814, UP000030591, UP000000484, UP000007476 15896266, 499268903, 336293199, 325510421, 15026072, 24638279 AEI34333.1, ADZ22057.1, AAK80955.1 NP_349615.1, WP_010966296.1 Q97EU2 THIC_CLOAB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 120614 fig|272562.1.peg.3144, fig|863638.3.peg.3049, fig|991791.3.peg.3044 436 436 yes 437877 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 411462 Dorea longicatena DSM 13814 Bacteria UP000004016 149754231 EDM64162.1 443 463 yes 437878 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1386, 1402, 1368424, 665958, 279010 Bacillus licheniformis, Bacillus licheniformis CG-B52, Bacillus sp. BT1B_CT2, Bacillus licheniformis ATCC 14580 Bacteria UP000036721, UP000017025, UP000003061, UP000000608 496687459, 765361947, 532552770, 317391453, 145902816, 52347215, 81609278 KJE30829.1, EQM28791.1, EFV72251.1, AAU22503.2, AAU39849.1 WP_009329002.1 Q65M65 THIC_BACLD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 726971 fig|279010.5.peg.1525 591 591 yes 437879 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 351604, 351605 Geobacter uraniireducens, Geobacter uraniireducens Rf4 Bacteria UP000006695 500474123, 146399693 ABQ28326.1 WP_011940957.1 fig|351605.4.peg.4102 431 435 yes 437880 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 344747 Planctomyces maris DSM 8797 Bacteria UP000003087 148844754 EDL59103.1 fig|344747.3.peg.3290 490 549 yes 437881 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 680, 338187 Vibrio campbellii, Vibrio harveyi ATCC BAA-1116 Bacteria UP000030534, UP000016232 501075794, 538263792, 156524301, 166228066 AGU94993.1, ABU69387.1 WP_012126625.1 A7N141 THIC_VIBCB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3481074 fig|338187.4.peg.286 640 646 yes 437882 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 80865, 180282, 1468410, 883100, 883101, 742013, 398578 Delftia tsuruhatensis, Delftia sp. RIT313, Delftia acidovorans CCUG 15835, Delftia acidovorans CCUG 274B, Delftia sp. Cs1-4, Delftia acidovorans SPH-1 Bacteria UP000027696, UP000024288, UP000014409, UP000014416, UP000009225, UP000000784 501159816, 828354098, 612094421, 512037964, 512035721, 333746141, 160363338 KLO61550.1, EZP52869.1, EPD37769.1, EPD35573.1, AEF91318.1, ABX34951.1 WP_012204233.1 fig|398578.3.peg.2304, fig|742013.3.peg.4389, fig|883100.3.peg.4877, fig|883101.3.peg.5135 625 647 yes 437883 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 62153, 391591 Vibrio shilonii, Vibrio shilonii AK1 Bacteria UP000003769 492974021, 148834804 EDL51789.1 WP_006074608.1 fig|391591.24.peg.4133 637 640 yes 437884 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 177758, 416591 Thermotoga lettingae, Thermotoga lettingae TMO Bacteria UP000053323, UP000002016 500835957, 157315206, 166987543 ABV34305.1 WP_012003781.1 A8F821 THIC_PSELT Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3677996 fig|416591.4.peg.1833 424 424 yes 437885 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 358766, 456442 Candidatus Methanoregula boonei, Candidatus Methanoregula boonei 6A8 Archaea UP000002408 501055681, 153999689, 166228038 ABS56112.1 WP_012107156.1 A7I8Q1 THIC_METB6 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3781070 fig|456442.10.peg.1588 420 425 yes 437886 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 666, 404974 Vibrio cholerae, Vibrio cholerae AM-19226 Bacteria UP000028983, UP000004693 445993255, 150422244 EDN14207.1 WP_000071110.1 fig|404974.3.peg.2587 639 645 yes 437887 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 33043, 411474, 1263071 Coprococcus eutactus, Coprococcus eutactus ATCC 27759, Coprococcus eutactus CAG:665 Bacteria, Environmental samples UP000003518, UP000017949 490988532, 158448869, 524226424 EDP25864.1 WP_004850265.1 fig|411474.6.peg.796 435 436 yes 437888 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 243274, 2335, 2336, 1157947, 1235863, 1230478, 1263836, 590168, 390874 Thermotoga maritima MSB8, Thermotoga maritima, Thermotoga sp. Cell2, Thermotoga sp. Xyl54, Thermotoga sp. TBGT1766, Thermotoga sp. TBGT1765, Thermotoga naphthophila RKU-10, Thermotoga petrophila RKU-1 Bacteria UP000008183 UP000018827, UP000033090, UP000062589, UP000030508, UP000030413, UP000030570, UP000000940, UP000006558 15643551, 490182277, 811642034, 811640093, 811630106, 728866332, 723264621, 723262743, 723261391, 568242737, 498539953, 281372685, 147734830, 4981317, 166228065, 7388311 AKE30443.1, AKE28569.1, AKE26705.1, AIY87511.1, KHC96036.1, KHC94180.1, KHC92839.1, AHD17458.1, AGL49714.1, ADA66247.1, ABQ46170.1, AAD35870.1 NP_228597.1, WP_004080892.1 Q9WZP5, A5IIZ7 THIC_THEMA, THIC_THEP1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3584073, 1676, 10362222 fig|243274.1.peg.781, fig|443254.3.peg.288, fig|390874.10.peg.141, fig|590168.4.peg.145 424 424 yes 437889 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 291048, 391592 Caminibacter mediatlanticus, Caminibacter mediatlanticus TB-2 Bacteria UP000003288 494738665, 149135597 EDM24076.1 WP_007474077.1 fig|391592.5.peg.719 459 460 yes 437890 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 392423 Hydrogenivirga sp. 128-5-R1-1 Bacteria UP000005981 495563927, 159880435 EDP74027.1 WP_008288506.1 fig|392423.3.peg.2499 450 455 yes 437891 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 150340 Vibrio sp. Ex25 Bacteria UP000002571 493794994, 262336440, 151937271 ACY50235.1, EDN56136.1 WP_006743063.1 fig|150340.18.peg.3785 640 646 yes 437892 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 58051 Moritella sp. PE36 Bacteria UP000004278 149805817 EDM65807.1 fig|58051.5.peg.3441 640 672 yes 437893 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1408, 315750 Bacillus pumilus, Bacillus pumilus SAFR-032 Bacteria UP000037521, UP000001355 500859244, 157681941, 166987533 ABV63085.1 WP_012010748.1 A8FFR8 THIC_BACP2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3427335 fig|315750.5.peg.2209 585 585 yes 437894 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 215813, 412755, 398580 Dinoroseobacter shibae, marine sediment metagenome, Dinoroseobacter shibae DFL 12 Bacteria, Environmental samples UP000006833 501138662, 816773263, 157914373, 157914174, 157913982 KKN51742.1, ABV95802.1, ABV95605.1, ABV95414.1 WP_012187122.1 fig|398580.10.peg.4219, fig|398580.10.peg.3816 597 602 yes 437895 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 777, 360115 Coxiella burnetii, Coxiella burnetii RSA 331 Bacteria UP000033654, UP000008557 501176826, 796966657, 161762020 KJY14804.1, ABX77662.1 WP_012220168.1 fig|1196327.3.peg.805, fig|1293501.3.peg.897, fig|360115.5.peg.459 544 548 yes 437896 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 280, 78245 Xanthobacter autotrophicus, Xanthobacter autotrophicus Py2 Bacteria UP000002417 501064229, 154161528 ABS68744.1 WP_012115490.1 fig|78245.7.peg.3861 612 624 yes 437897 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 816, 1339352, 997891, 469593, 457394, 435590 Bacteroides vulgatus str. 3975 RP4, Bacteroides vulgatus CL09T03C04, Bacteroides sp. 3_1_40A, Bacteroides sp. 4_3_47FAA, Bacteroides vulgatus ATCC 8482 Bacteria UP000027661, UP000004219, UP000003878, UP000003502, UP000002861 492460257, 649539776, 392681570, 317387167, 254834582, 149934463 KDS46751.1, EIY74928.1, EFV68045.1, EET14891.1, ABR41161.1 WP_005852754.1 fig|997891.3.peg.3540, fig|435590.6.peg.3295, fig|457394.3.peg.1080, fig|469593.3.peg.1299 566 566 yes 437898 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 223926, 670, 1288785, 1288784, 1288781, 1238204, 1238216, 1429044, 1238205, 1238217, 1238201, 1238207, 1238211, 1238212, 1238210, 1238200, 1238206, 1238199, 1238218, 1238209, 1238213, 1238208, 627611, 563772, 563773, 563771, 419109 Vibrio parahaemolyticus RIMD 2210633, Vibrio parahaemolyticus, Vibrio parahaemolyticus 930, Vibrio parahaemolyticus 863, Vibrio parahaemolyticus VP551, Vibrio parahaemolyticus VP-48, Vibrio parahaemolyticus EKP-021, Vibrio parahaemolyticus UCM-V493, Vibrio parahaemolyticus V14/01, Vibrio parahaemolyticus EKP-026, Vibrio parahaemolyticus 861, Vibrio parahaemolyticus Peru-288, Vibrio parahaemolyticus IDH02189, Vibrio parahaemolyticus EKP-028, Vibrio parahaemolyticus IDH02640, Vibrio parahaemolyticus 605, Vibrio parahaemolyticus B-265, Vibrio parahaemolyticus 949, Vibrio parahaemolyticus VP-NY4, Vibrio parahaemolyticus VP232, Vibrio parahaemolyticus NIHCB0603, Vibrio parahaemolyticus VP250, Vibrio parahaemolyticus K5030, Vibrio parahaemolyticus AQ4037, Vibrio parahaemolyticus AN-5034, Vibrio parahaemolyticus Peru-466, Vibrio parahaemolyticus AQ3810 Bacteria UP000002493, UP000028114, UP000032044, UP000032081, UP000032045, UP000024905, UP000019363, UP000019451, UP000019825, UP000023336, UP000024615, UP000022580, UP000022277, UP000022257, UP000023473, UP000019047, UP000018953, UP000016148, UP000015768, UP000015786, UP000015704, UP000015828, UP000005042, UP000005571, UP000005822, UP000003099, UP000019490 28899801, 491607501, 820927195, 808786049, 807089345, 778244809, 767873168, 757995163, 757966162, 757965153, 726142534, 655694838, 655693271, 655680358, 589847985, 585142352, 584471844, 582059471, 577082265, 576896994, 575566744, 575551385, 575551289, 575489512, 573506926, 572319770, 532607952, 532401495, 532400476, 532391888, 532389976, 308113714, 308107200, 308094157, 308088946, 149746969, 31077018, 28808053 KKX77762.1, KKF07908.1, KKC78272.1, KJR38579.1, KJH12497.1, KIT07759.1, KIS79231.1, KIS78228.1, KHF13221.1, KED86985.1, KED85525.1, KED73750.1, EXJ25061.1, EWM34644.1, AHJ01065.1, EVT76504.1, EUD13318.1, EUC21767.1, ETX66353.1, ETX51504.1, ETX51412.1, ETX21605.1, ETT07084.1, ETS19737.1, EQM41746.1, EQM08022.1, EQM07017.1, EQL98498.1, EQL96607.1, EFO51254.1, EFO44740.1, EFO43852.1, EFO38641.1, EDM57957.1 NP_799406.1, WP_005465061.1 Q87KF0 THIC_VIBPA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 4185536, 341539 fig|223926.1.peg.3027, fig|627611.3.peg.2890, fig|563772.3.peg.2265, fig|563771.3.peg.2796, fig|563773.3.peg.1017, fig|419109.14.peg.4803 640 646 yes 437899 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 411459 Ruminococcus obeum ATCC 29174 Bacteria UP000006002 149834011 EDM89091.1 fig|411459.7.peg.3192 562 709 yes 437900 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 24, 319224 Shewanella putrefaciens, Shewanella putrefaciens CN-32 Bacteria UP000006699 500268388, 145564710, 166228061 ABP75645.1 WP_011919272.1 A4Y6R2 THIC_SHEPC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3438606 fig|319224.13.peg.1762 655 712 yes 437901 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 408, 419610 Methylobacterium extorquens, Methylobacterium extorquens PA1 Bacteria UP000008546 501210189, 163662642 ABY30009.1 WP_012253207.1 fig|419610.10.peg.1615 625 630 yes 437902 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 411476 Bacteroides ovatus ATCC 8483 Bacteria UP000005475 156110119 EDO11864.1 fig|411476.11.peg.113 565 565 yes 437903 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28141, 290339 Cronobacter sakazakii, Cronobacter sakazakii ATCC BAA-894 Bacteria UP000027472, UP000000260 501075121, 156534057 ABU78883.1 WP_012126008.1 fig|290339.8.peg.3276 626 633 yes 437904 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 298653 Frankia sp. EAN1pec Bacteria UP000001313 158112763 ABW14960.1 fig|298653.4.peg.5491 591 606 yes 437905 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 410330, 412965 Calyptogena okutanii thioautotrophic gill symbiont, Candidatus Vesicomyosocius okutanii HA Bacteria UP000000247 500420021, 226695855, 146326358 WP_011929771.1 A5CX15 THIC_VESOH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3671820 fig|412965.6.peg.371, fig|412965.8.peg.377 621 622 yes 437906 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 256618, 402881 Parvibaculum lavamentivorans, Parvibaculum lavamentivorans DS-1 Bacteria UP000006377 501059715, 154156546, 171769607 ABS63763.1 WP_012111068.1 A7HV30 THIC_PARL1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3640619 fig|402881.6.peg.2120 605 623 yes 437907 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 986, 376686 Flavobacterium johnsoniae, Flavobacterium johnsoniae UW101 Bacteria UP000006694 500932193, 146153781 ABQ04635.1 WP_012023679.1 fig|376686.10.peg.1648 607 607 yes 437908 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 387092 Nitratiruptor sp. SB155-2 Bacteria UP000001118 501029890, 166228050, 151422206 WP_012081973.1 A6Q2K1 THIC_NITSB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3580122 fig|387092.5.peg.631 444 444 yes 437909 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 64091, 2242, 478009 Halobacterium sp. NRC-1, Halobacterium salinarum, Halobacterium salinarum R1 Archaea UP000000554 UP000000554, UP000001321 15789892, 499204952, 169235613, 10580294, 229558542, 167726679, 24638283 AAG19196.1 NP_279716.1, WP_010902492.1, YP_001688813.1 B0R400, Q9HRG2 THIC_HALS3, THIC_HALSA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 68685, 3796357 fig|64091.1.peg.732 457 476 yes 437910 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 85701, 382640 Bartonella tribocorum, Bartonella tribocorum CIP 105476 Bacteria UP000025228, UP000001592 501188274, 605050286, 189030270, 161017625 WP_012231296.1 A9IRH7 THIC_BART1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3569253 fig|382640.5.peg.803 599 606 yes 437911 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 13687, 392499 Sphingomonas wittichii RW1 Bacteria UP000001989 500995952, 148501294, 166228062 ABQ69548.1 WP_012049393.1 A5VB82 THIC_SPHWW Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7096222 fig|400971.3.peg.3170, fig|392499.14.peg.3752 617 619 yes 437912 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1219, 93060 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9215 Bacteria UP000002014 500856990, 157388793, 166987540 ABV51498.1 WP_012008494.1 A8G7B7 THIC_PROM2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1718410 fig|93060.3.peg.1938 453 456 yes 437913 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 316278 Synechococcus sp. RCC307 Bacteria UP000001115 500467713, 166228064, 147849538 WP_011934547.1 A5GQ73 THIC_SYNR3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3434174 fig|316278.3.peg.130 463 466 yes 437914 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 96345, 402612, 1452724 Flavobacterium psychrophilum, Flavobacterium psychrophilum JIP02/86, Flavobacterium psychrophilum FPG3 Bacteria UP000055977, UP000006394, UP000029244 500639301, 150024531, 806975579, 806973264, 806970896, 806968524, 806966155, 806964422, 697782259, 684211040, 672597991, 666892849, 666890581, 666888314, 666885951, 666883796, 666881518, 149771072 AKC28071.1, AKC25757.1, AKC23390.1, AKC21019.1, AKC18651.1, AKC16919.1, AIT64721.1, AIN73325.1, AIJ36966.1, AIG40670.1, AIG38403.1, AIG36137.1, AIG33775.1, AIG31621.1, AIG29344.1 WP_011962597.1, YP_001295357.1 3634481 fig|402612.4.peg.422 607 607 yes 437915 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 62322, 402882 Shewanella baltica, Shewanella baltica OS185 Bacteria UP000006387 501037330, 151365461 ABS08461.1 WP_012089306.1 fig|402882.10.peg.2480 655 707 yes 437916 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 197, 32022, 889218, 691338, 645464, 407148 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni, Campylobacter jejuni subsp. jejuni 55037, Campylobacter jejuni subsp. jejuni 327, Campylobacter jejuni subsp. jejuni M1, Campylobacter jejuni subsp. jejuni 81116 Bacteria UP000065538, UP000032540, UP000004894, UP000003542, UP000008145, UP000002013 488955917, 669635269, 380613923, 315931108, 307747385, 157385710, 172047069 AII24164.1, EIB33381.1, EFV10082.1, ADN90655.1, ABV52025.1 WP_002866992.1 A8FKN8 THIC_CAMJ8 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3660654 fig|889218.3.peg.319, fig|407148.6.peg.435, fig|645464.3.peg.433, fig|691338.3.peg.1604 430 430 yes 437917 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 46503, 999421, 411477 Parabacteroides merdae, Parabacteroides merdae CL09T00C40, Parabacteroides merdae ATCC 43184 Bacteria UP000001214, UP000004276 491866364, 409242335, 154085247 EKN35098.1, EDN84292.1 WP_005641869.1 fig|999421.3.peg.743, fig|411477.4.peg.3594 567 568 yes 437918 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 487, 374833 Neisseria meningitidis, Neisseria meningitidis 053442 Bacteria UP000050419, UP000001177 501177905, 161594705, 189030276 ABX72365.1 WP_012221163.1 A9M0A4 THIC_NEIM0 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3543419, 7761638 fig|374833.4.peg.166 625 633 yes 437919 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 61435, 1432061, 1193806, 216389 Dehalococcoides ethenogenes, Dehalococcoides mccartyi CG5, Dehalococcoides mccartyi BTF08, Dehalococcoides sp. BAV1 Bacteria UP000054393, UP000031752, UP000011727, UP000002607 500358981, 670945551, 452112061, 146270293, 189030273 AII60822.1, AGG07792.1, ABQ17285.1 WP_011929031.1 A5FR94 THIC_DEHMB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3828642 fig|216389.10.peg.719, fig|1193806.4.peg.666 430 431 yes 437920 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 266834, 382, 1286640, 707241, 1401243 Sinorhizobium meliloti 1021, Sinorhizobium meliloti, Sinorhizobium meliloti 2011, Sinorhizobium meliloti SM11, Sinorhizobium meliloti RU11/001 Bacteria UP000001976, UP000028953, UP000011827, UP000009045, UP000035764 16265275, 499283251, 675830955, 459645491, 336036998, 589249075, 21759456, 15141415 AIM02642.1, AGG72536.1, AEH82928.1 NP_438067.1, WP_010976311.1 Q92TI9 THIC_RHIME Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 132842 fig|1286640.3.peg.3002, fig|1194719.3.peg.6201, fig|1194716.3.peg.5738, fig|707241.3.peg.5769, fig|1194715.3.peg.4464, fig|266834.1.peg.6162, fig|1194707.3.peg.8596, fig|1194714.3.peg.5888, fig|1194709.3.peg.6773 601 611 yes 437921 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 243230, 1299 Deinococcus radiodurans R1, Deinococcus radiodurans Bacteria UP000002524 UP000002524 15807844, 499191895, 6460490, 24638290 AAF12196.1 NP_285499.1, WP_010889435.1 Q9RYX8 THIC_DEIRA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 43449 fig|243230.1.peg.2989 605 607 yes 437922 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 411470 Ruminococcus gnavus ATCC 29149 Bacteria UP000004410 153793524 EDN75944.1 fig|411470.6.peg.3095 436 436 yes 437923 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2209, 1236903, 1434113, 1434114, 213585, 1434115, 1434117, 192952 Methanosarcina mazei, Methanosarcina mazei Tuc01, Methanosarcina mazei C16, Methanosarcina mazei LYC, Methanosarcina mazei S-6, Methanosarcina mazei SarPi, Methanosarcina mazei WWM610, Methanosarcina mazei Go1 Archaea UP000034872, UP000011718, UP000033071, UP000033063, UP000033097, UP000033116, UP000033058, UP000000595 499343435, 452209603, 814933196, 814929986, 814922252, 814920092, 814917111, 814916900, 814913177, 814902159, 814901591, 814900330, 814896259, 814894581, 814886614, 814885218, 814881809, 814873048, 814868251, 814868082, 814865701, 814865348, 814857366, 814857244, 814854798, 814847460, 814844307, 814843064, 814830973, 814830888, 814828066, 814821561, 814818093, 814816737, 814816154, 814812709, 814808262, 814804980, 814799051, 814798641, 814796763, 814792421, 814786094, 814785054, 814778737, 814769428, 814768873, 814768796, 814760559, 814759482, 814756489, 814754670, 814747710, 814747632, 814728704, 814720974, 814716917, 814716310, 805373802, 805370090, 805366359, 805362990, 805359485, 452099505, 24638253 KKI05134.1, KKI02075.1, KKH94737.1, KKH92695.1, KKH89863.1, KKH89663.1, KKH86138.1, KKH75763.1, KKH75218.1, KKH74029.1, KKH70184.1, KKH68657.1, KKH61301.1, KKH59992.1, KKH56795.1, KKH48546.1, KKH44034.1, KKH43871.1, KKH41613.1, KKH41279.1, KKH33676.1, KKH33562.1, KKH31234.1, KKH24281.1, KKH21294.1, KKH20106.1, KKH08569.1, KKH08486.1, KKH05792.1, KKG99558.1, KKG96271.1, KKG94982.1, KKG94435.1, KKG91164.1, KKG86978.1, KKG83860.1, KKG78249.1, KKG77876.1, KKG76101.1, KKG72027.1, KKG66067.1, KKG65059.1, KKG59020.1, KKG50137.1, KKG49601.1, KKG49526.1, KKG41694.1, KKG40677.1, KKG37838.1, KKG36119.1, KKG29547.1, KKG29471.1, KKG11369.1, KKG03984.1, KKG00123.1, KKF99537.1, AKB70172.1, AKB66824.1, AKB63471.1, AKB60264.1, AKB39274.1, AGF96445.1 WP_011032974.1, YP_007489717.1 Q8PY39, A0A0F8EJ27, A0A0E3PUN1, M1Q2H9, A0A0E3RNA1, A0A0E3LTG3, A0A0E3R626, A0A0E3RVF4 THIC2_METMA Phosphomethylpyrimidine synthase 2 {ECO:0000255|HAMAP-Rule:MF_00089} A0A0F8EJ27_METMZ, A0A0E3PUN1_METMZ, M1Q2H9_METMZ, A0A0E3RNA1_METMZ, A0A0E3LTG3_METMZ, A0A0E3R626_METMZ, A0A0E3RVF4_METMZ 248990 fig|192952.1.peg.1025 428 428 yes 437924 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 303, 1227924, 1193146, 1196325, 351746 Pseudomonas putida, Pseudomonas putida TRO1, Pseudomonas putida LS46, Pseudomonas putida DOT-T1E, Pseudomonas putida F1 Bacteria UP000054813, UP000013237, UP000006401, UP000006503, UP000006553 489342305, 480581121, 471350375, 397330687, 148514058, 166228058 ENY74475.1, EMR48333.1, AFO47046.1, ABQ80918.1 WP_003249473.1 A5W9V8 THIC_PSEP1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6986965 fig|1196325.3.peg.1194, fig|1193146.3.peg.3495, fig|1193499.3.peg.2265, fig|1227924.3.peg.5267, fig|1081940.5.peg.4954, fig|231023.4.peg.1897, fig|351746.4.peg.4741 625 626 yes 437925 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2209, 192952 Methanosarcina mazei, Methanosarcina mazei Go1 Archaea UP000034872, UP000000595 499342596, 814930715, 814929483, 814923419, 814921144, 814918368, 814912484, 814909446, 814903967, 814902797, 814897642, 814895076, 814893122, 814891842, 814886516, 814879971, 814879245, 814875395, 814863104, 814862589, 814858615, 814854149, 814846563, 814841225, 814838303, 814826667, 814816347, 814810207, 814807136, 814803517, 814793468, 814718433, 814716377, 814714744, 24638254 KKI02768.1, KKI01584.1, KKH95845.1, KKH93685.1, KKH91051.1, KKH85484.1, KKH82618.1, KKH77469.1, KKH76369.1, KKH71482.1, KKH69111.1, KKH67274.1, KKH66100.1, KKH61212.1, KKH55060.1, KKH54372.1, KKH50778.1, KKH39144.1, KKH38655.1, KKH34864.1, KKH30614.1, KKH23423.1, KKH18343.1, KKH15546.1, KKH04459.1, KKG94619.1, KKG88812.1, KKG85903.1, KKG82462.1, KKG73004.1, KKG01568.1, KKF99603.1, KKF98045.1 WP_011032136.1 Q8Q0F4, A0A0F8Q8J8 THIC1_METMA Phosphomethylpyrimidine synthase 1 {ECO:0000255|HAMAP-Rule:MF_00089} A0A0F8Q8J8_METMZ 248147 fig|192952.1.peg.182 428 428 yes 437926 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 176299, 1183400, 358 Agrobacterium tumefaciens str. C58, Agrobacterium tumefaciens Bacteria UP000000813, UP000064781 159185271, 499275016, 796557633, 666382630, 159140531, 24638268 KJX87222.1, KEY52302.1, AAK88293.2 NP_355508.2, WP_010972409.1 Q8UCC9 THIC_AGRFC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 128484 fig|176299.10.peg.2573 598 607 yes 437927 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 387093 Sulfurovum sp. NBC37-1 Bacteria UP000006378 500720846, 151423983 WP_011980219.1 fig|387093.4.peg.515 623 629 yes 437928 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 39152, 444158 Methanococcus maripaludis, Methanococcus maripaludis C6 Archaea UP000000791 501148456, 159886645, 238686949 ABX01582.1 WP_012193474.1 A9A8A9 THIC_METM6 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3752834 fig|444158.3.peg.755 426 426 yes 437929 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 197, 889249, 398000 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni LMG 9217, Campylobacter jejuni subsp. jejuni CG8486 Bacteria UP000065538, UP000003667, UP000006165 488947941, 380626653, 145844818 EIB45101.1, EDK21922.1 WP_002859016.1 fig|889249.3.peg.738, fig|1293289.3.peg.439, fig|398000.3.peg.292 430 430 yes 437930 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 851, 393480, 76857 Fusobacterium nucleatum, Fusobacterium nucleatum subsp. polymorphum ATCC 10953, Fusobacterium nucleatum subsp. polymorphum Bacteria UP000001921, UP000058191 492592114, 148323722, 777193778 EDK88972.1 WP_005897551.1 fig|393480.8.peg.819 433 433 yes 437931 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1491, 758678, 441772 Clostridium botulinum, Clostridium botulinum F str. 230613, Clostridium botulinum F str. Langeland Bacteria UP000030128, UP000002367, UP000002410 501049010, 816648266, 295320190, 152936270, 166987536 KKM40932.1, ADG00568.1, ABS41768.1 WP_012100699.1 A7GHD2 THIC_CLOBL Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3747961 fig|441772.13.peg.2886, fig|758678.3.peg.3083 437 437 yes 437932 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 59201, 941187, 930774, 930776, 930775, 1016998 Salmonella enterica, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Inverness str. ATCC 10720, Salmonella enterica subsp. enterica serovar Paratyphi B str. ATCC 10719, Salmonella enterica subsp. enterica serovar Paratyphi B str. ATCC 51962, Salmonella enterica subsp. enterica serovar Paratyphi B str. ATCC 19940, Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7 Bacteria UP000054489, UP000033855, UP000017397, UP000017627, UP000017626, UP000017277, UP000008556 446030565, 735793744, 554258366, 554157944, 554137586, 554135186, 161366667, 189030296 KHP63598.1, ESG94718.1, ESF97711.1, ESF77861.1, ESF75556.1, ABX70435.1 WP_000108420.1 A9N0K6 THIC_SALPB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 4401568, 4823795, 4852180, 4846666, 3390669, 4407230 fig|272994.5.peg.4276 626 631 yes 437933 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 338192, 436308 Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1 Archaea UP000000792 501171056, 161528051, 160339352 ABX12439.1 WP_012214926.1, YP_001581877.1 A9A226 A9A226_NITMS 3725345 fig|436308.3.peg.539 442 442 yes 437934 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1390, 1412898, 326423 Bacillus amyloliquefaciens, Bacillus amyloliquefaciens CC178, Bacillus amyloliquefaciens FZB42 Bacteria UP000027101, UP000017759, UP000001120 501065906, 556018559, 154351192, 166228011 AGZ55587.1, ABS73271.1 WP_012117130.1 A7Z2P5 THIC_BACVZ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3455283 fig|326423.3.peg.865 590 590 yes 437935 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 60890, 383629 Phaeobacter gallaeciensis, Phaeobacter gallaeciensis 2.10 Bacteria UP000002913 504686914, 398652925 AFO86895.1 WP_014874016.1 fig|383629.4.peg.2657 594 602 yes 437936 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 314289 Vibrio sp. AND4 Bacteria UP000005159 497529645, 159173027 EDP57861.1 WP_009843843.1 fig|314289.8.peg.3020 640 646 yes 437937 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 168697, 391037 Salinispora arenicola, Salinispora arenicola CNS-205 Bacteria UP000001153 501135677, 157918628 ABW00056.1 WP_012184292.1 fig|1169185.3.peg.3216, fig|1169162.3.peg.2895, fig|1169166.3.peg.4341, fig|1169175.3.peg.4988, fig|1169167.3.peg.2492, fig|1169176.3.peg.3143, fig|391037.3.peg.4119, fig|1169177.3.peg.3449, fig|1137264.3.peg.1790, fig|1169178.3.peg.3125, fig|1149863.3.peg.3695, fig|1169168.3.peg.2697, fig|1169165.3.peg.3747, fig|1169179.3.peg.1856, fig|1169163.3.peg.4046, fig|1169173.3.peg.5056 530 530 yes 437938 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1520, 864803, 290402 Clostridium beijerinckii, Clostridium beijerinckii ATCC 35702, Clostridium beijerinckii NCIMB 8052 Bacteria UP000031866, UP000029902, UP000000565 501007721, 698935715, 149905765 AIU04051.1, ABR36598.1 WP_012060645.1 fig|290402.34.peg.4408 436 436 yes 437939 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 122586, 487, 1386087, 1190580, 1190579, 1190576, 1190570, 1190571, 1145162, 1145161, 1145160, 1095689, 1095690, 1095701, 909420 Neisseria meningitidis MC58, Neisseria meningitidis, Neisseria meningitidis LNP21362, Neisseria meningitidis NM3230, Neisseria meningitidis NM3173, Neisseria meningitidis NM1476, Neisseria meningitidis 2002030, Neisseria meningitidis NM3141, Neisseria meningitidis M13265, Neisseria meningitidis NM477, Neisseria meningitidis 2002020, Neisseria meningitidis NM418, Neisseria meningitidis M13255, Neisseria meningitidis NM422, Neisseria meningitidis H44/76 Bacteria UP000000425, UP000050419, UP000031161, UP000015771, UP000015896, UP000015759, UP000015866, UP000015684, UP000013322, UP000013350, UP000013331, UP000010757, UP000010739, UP000010741, UP000008124 15677863, 488173138, 744798404, 530920532, 530918954, 530912368, 530897768, 530897709, 485360593, 485355498, 485353840, 432225150, 432220146, 432200409, 330710179, 325201087, 316983923, 7227302, 24638286 AJC63192.1, EQD18000.1, EQD16526.1, EQD10322.1, EQC96627.1, EQC96573.1, EOC21322.1, EOC16705.1, EOC15170.1, ELK80903.1, ELK75971.1, ELK56502.1, AEC38406.1, ADY96542.1, EFV62902.1, AAF42361.1 NP_275031.1, WP_002244346.1 Q9JXI0 THIC_NEIMB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 141093 fig|1145160.3.peg.2591, fig|1095689.3.peg.2838, fig|909420.3.peg.2667, fig|122586.1.peg.1965, fig|1095690.3.peg.2740, fig|1095701.3.peg.2788, fig|1145162.3.peg.1636, fig|1145161.3.peg.2733 625 633 yes 437940 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2187, 406327 Methanococcus vannielii, Methanococcus vannielii SB Archaea UP000001107 501013123, 150012635, 166228044 ABR55087.1 WP_012066002.1 A6URG5 THIC_METVS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3659689 fig|406327.7.peg.1220 426 426 yes 437941 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 392423 Hydrogenivirga sp. 128-5-R1-1 Bacteria UP000005981 495562787, 159881785 EDP75294.1 WP_008287366.1 fig|392423.3.peg.1503 453 457 yes 437942 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 386585, 562, 83334, 1330457, 155864, 1328859, 1446606, 1446607, 1446651, 1446649, 1446618, 1446620, 1446617, 1446698, 1446616, 1446697, 1446696, 1446695, 1446693, 1446694, 1446691, 1446690, 1446689, 1446688, 1446687, 1446685, 1446686, 1446684, 1446683, 1446682, 1446681, 1446680, 1446679, 1446678, 1446677, 1446676, 1446675, 1446673, 1446674, 1446672, 1446671, 1446668, 1446667, 1446666, 1446664, 1446665, 1446663, 1446662, 1446661, 1446659, 1446660, 1446657, 1446658, 1446655, 1446653, 1446654, 1446652, 1446611, 1446610, 1446612, 1446622, 1446623, 1446624, 1446625, 1446626, 1446627, 1446628, 1446629, 1446630, 1446631, 1446614, 1446613, 1446615, 1446632, 1446633, 1446634, 1446635, 1446636, 1446637, 1446638, 1446640, 1446639, 1446641, 1446643, 1446642, 1446645, 1446644, 1446646, 1446647, 1446648, 1446650, 1446656, 1446692, 1446619, 1446621, 1404261, 1207036, 1207037, 1151236, 1151235, 1081891, 1081894, 1081895, 1151242, 1151241, 1151240, 1151239, 1151224, 1151246, 1151228, 1151227, 1151238, 1151237, 1151251, 1151250, 1151249, 1151244, 550673, 1151248, 1151247, 1151243, 1151234, 1207038, 1207035, 1081892, 1081896, 1081890, 1081888, 1151233, 1151232, 1151231, 1151216, 1151215, 1151222, 1151221, 1151220, 1151219, 1151218, 1151217, 1151226, 1151225, 1081889, 1151213, 1151214, 1005423, 1051346, 1051347, 1051352, 1005439, 1051348, 1005492, 1005513, 1005512, 1005487, 1051351, 1051350, 1051349, 1005436, 1005437, 1005438, 1005440, 1005432, 1005430, 1005433, 1081887, 1005434, 1005419, 1005414, 1005424, 1005422, 1005421, 1005420, 1005418, 1005416, 1005415, 1005413, 1005412, 1005411, 1005410, 1005407, 1005408, 1005406, 1005405, 1005403, 1005404, 1005401, 1005402, 1005396, 1005399, 1005398, 1005469, 1005463, 1005397, 1005467, 1005460, 1005466, 1005461, 1005455, 1005450, 1005452, 1005441, 1005482, 1005486, 1005554, 1005553, 1005551, 1005552, 1005549, 1005547, 1005546, 1005545, 1005544, 1005543, 1005542, 1005541, 1005539, 1005538, 1005537, 1005506, 1005561, 1005560, 1005559, 1005557, 1005555, 1005511, 1005514, 1005498, 1005489, 1005479, 1005484, 1005485, 1005480, 1005477, 1005470, 1005472, 1005474, 1005505, 1005483, 1005491, 1005548, 1005540, 1005536, 1005535, 1005534, 1005533, 1005532, 1005531, 1005530, 1005529, 1005528, 1005527, 1005526, 1005525, 1005524, 1005523, 1005521, 1005522, 1005520, 1005519, 1005517, 1005518, 1005516, 1005515, 1005510, 1005509, 1005507, 1005508, 1005504, 1005503, 1005502, 1005501, 1005500, 1005499, 1005497, 1005496, 1005495, 1005494, 1005493, 1005490, 1005488, 1005478, 1005481, 1005476, 1005473, 1005471, 1005475, 741093, 868154, 868156, 868152, 868153, 868151, 868150, 868149, 868148, 868147, 868146, 868144, 868145, 868143, 997824, 997825, 926032, 926029, 926028, 926027, 926026, 941435, 544404, 502346, 444450, 444449, 444448, 444447, 478007, 478008, 478006, 478005, 478004, 444453, 444452, 444451 Escherichia coli O157:H7 str. Sakai, Escherichia coli, Escherichia coli O157:H7, Escherichia coli O157:H7 str. SS52, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. SS17, Escherichia coli O157 str. 2010EL-2044, Escherichia coli O157 str. 2010EL-2045, Escherichia coli O157:H7 str. 2011EL-2313, Escherichia coli O157:H7 str. 2011EL-2290, Escherichia coli O157:H7 str. 2009EL1449, Escherichia coli O157:H7 str. 2009EL1913, Escherichia coli O157:H7 str. 2009C-4258, Escherichia coli O157:NM str. 08-4540, Escherichia coli O157:H7 str. 08-4529, Escherichia coli O157:H7 str. K7140, Escherichia coli O157:H7 str. K6687, Escherichia coli O157:H7 str. K6676, Escherichia coli O157:H7 str. K5852, Escherichia coli O157:H7 str. K6590, Escherichia coli O157:H7 str. K5609, Escherichia coli O157:H7 str. K5607, Escherichia coli O157:H7 str. K5602, Escherichia coli O157:H7 str. K5467, Escherichia coli O157:H7 str. K5460, Escherichia coli O157:H7 str. K5449, Escherichia coli O157:H7 str. K5453, Escherichia coli O157:H7 str. K5448, Escherichia coli O157:H7 str. K5418, Escherichia coli O157:H7 str. K4527, Escherichia coli O157:H7 str. K4406, Escherichia coli O157:H7 str. K4405, Escherichia coli O157:H7 str. K4396, Escherichia coli O157:H7 str. K2854, Escherichia coli O157:H7 str. K2845, Escherichia coli O157:H7 str. K2622, Escherichia coli O157:H7 str. K2581, Escherichia coli O157:H7 str. K2192, Escherichia coli O157:H7 str. K2324, Escherichia coli O157:H7 str. K2191, Escherichia coli O157:H7 str. K2188, Escherichia coli O157:H7 str. K1845, Escherichia coli O157:H7 str. K1796, Escherichia coli O157:H7 str. K1795, Escherichia coli O157:H7 str. K1792, Escherichia coli O157:H7 str. K1793, Escherichia coli O157:H7 str. K1420, Escherichia coli O157:H7 str. H2498, Escherichia coli O157:H7 str. H2495, Escherichia coli O157:H7 str. F7410, Escherichia coli O157:H7 str. G5303, Escherichia coli O157:H7 str. F7377, Escherichia coli O157:H7 str. F7384, Escherichia coli O157:H7 str. F6751, Escherichia coli O157:H7 str. F6749, Escherichia coli O157:H7 str. F6750, Escherichia coli O157:H7 str. F6142, Escherichia coli O157:H7 str. 07-3091, Escherichia coli O157:H7 str. 06-4039, Escherichia coli O157:H7 str. 07-3391, Escherichia coli O157:H7 str. 2010C-4979C1, Escherichia coli O157:H7 str. 2011EL-1107, Escherichia coli O157:H7 str. 2011EL-2090, Escherichia coli O157:H7 str. 2011EL-2091, Escherichia coli O157:H7 str. 2011EL-2092, Escherichia coli O157:H7 str. 2011EL-2093, Escherichia coli O157:H7 str. 2011EL-2094, Escherichia coli O157:H7 str. 2011EL-2096, Escherichia coli O157:H7 str. 2011EL-2097, Escherichia coli O157:H7 str. 2011EL-2098, Escherichia coli O157:H7 str. 08-3527, Escherichia coli O157:H7 str. 08-3037, Escherichia coli O157:H7 str. 08-4169, Escherichia coli O157:H7 str. 2011EL-2099, Escherichia coli O157:H7 str. 2011EL-2101, Escherichia coli O157:H7 str. 2011EL-2103, Escherichia coli O157:H7 str. 2011EL-2104, Escherichia coli O157:H7 str. 2011EL-2105, Escherichia coli O157:H7 str. 2011EL-2106, Escherichia coli O157:H7 str. 2011EL-2107, Escherichia coli O157:H7 str. 2011EL-2109, Escherichia coli O157:H7 str. 2011EL-2108, Escherichia coli O157:H7 str. 2011EL-2111, Escherichia coli O157:H7 str. 2011EL-2113, Escherichia coli O157:H7 str. 2011EL-2112, Escherichia coli O157:H7 str. 2011EL-2286, Escherichia coli O157:H7 str. 2011EL-2114, Escherichia coli O157:H7 str. 2011EL-2287, Escherichia coli O157:H7 str. 2011EL-2288, Escherichia coli O157:H7 str. 2011EL-2289, Escherichia coli O157:H7 str. 2011EL-2312, Escherichia coli O157:H7 str. F7350, Escherichia coli O157:H7 str. K5806, Escherichia coli O157:H7 str. 2009EL1705, Escherichia coli O157:H7 str. 2009EL2109, Escherichia coli ATCC BAA-2192, Escherichia coli Tx3800, Escherichia coli Tx1686, Escherichia coli B90, Escherichia coli B89, Escherichia coli T1282_01, Escherichia coli 09BKT024447, Escherichia coli 08BKT77219, Escherichia coli B86, Escherichia coli B85, Escherichia coli B84, Escherichia coli B83, Escherichia coli B5-2, Escherichia coli B49-2, Escherichia coli B40-2, Escherichia coli B40-1, Escherichia coli B17, Escherichia coli B15, Escherichia coli B114, Escherichia coli B113, Escherichia coli B112, Escherichia coli B109, Escherichia coli B108, Escherichia coli B106, Escherichia coli B105, Escherichia coli B104, Escherichia coli B103, Escherichia coli 2886-75, Escherichia coli 14A, Escherichia coli T234_00, Escherichia coli T1840_97, Escherichia coli Bd5610_99, Escherichia coli 08BKT055439, Escherichia coli B95, Escherichia coli B94, Escherichia coli B93, Escherichia coli B7-2, Escherichia coli B7-1, Escherichia coli B36-2, Escherichia coli B36-1, Escherichia coli B29-2, Escherichia coli B29-1, Escherichia coli B28-2, Escherichia coli B28-1, Escherichia coli B26-2, Escherichia coli B26-1, Escherichia coli 09BKT076207, Escherichia coli B102, Escherichia coli B107, Escherichia coli 99.0670, Escherichia coli 95.0083, Escherichia coli 3.4880, Escherichia coli PA35, Escherichia coli 99.1781, Escherichia coli 7.1982, Escherichia coli PA8, Escherichia coli PA48, Escherichia coli PA47, Escherichia coli PA2, Escherichia coli PA19, Escherichia coli PA13, Escherichia coli PA11, Escherichia coli 99.1805, Escherichia coli 99.1793, Escherichia coli 99.1775, Escherichia coli 99.1753, Escherichia coli 99.0839, Escherichia coli 99.0816, Escherichia coli 99.0815, Escherichia coli 09BKT078844, Escherichia coli 99.0814, Escherichia coli 97.0010, Escherichia coli 96.0109, Escherichia coli 99.0713, Escherichia coli 99.0678, Escherichia coli 99.0672, Escherichia coli 97.0007, Escherichia coli 97.1742, Escherichia coli 97.0003, Escherichia coli 96.0107, Escherichia coli 96.0932, Escherichia coli 96.0939, Escherichia coli 96.0427, Escherichia coli 96.0428, Escherichia coli 95.1288, Escherichia coli 95.0943, Escherichia coli 95.0183, Escherichia coli 94.0618, Escherichia coli 93.0055, Escherichia coli 93.0056, Escherichia coli 90.0039, Escherichia coli 90.2281, Escherichia coli 88.1467, Escherichia coli 89.0511, Escherichia coli 88.1042, Escherichia coli 10.0821, Escherichia coli 8.0416, Escherichia coli 88.0221, Escherichia coli 10.0869, Escherichia coli 8.2524, Escherichia coli 10.0833, Escherichia coli 8.0586, Escherichia coli 6.0172, Escherichia coli 3.4870, Escherichia coli 5.2239, Escherichia coli 0.1304, Escherichia coli FRIK523, Escherichia coli NE098, Escherichia coli EC1870, Escherichia coli EC1869, Escherichia coli EC1866, Escherichia coli EC1868, Escherichia coli EC1864, Escherichia coli EC1862, Escherichia coli EC1856, Escherichia coli EC1850, Escherichia coli EC1849, Escherichia coli EC1848, Escherichia coli EC1847, Escherichia coli EC1846, Escherichia coli EC1737, Escherichia coli EC1736, Escherichia coli EC1735, Escherichia coli PA38, Escherichia coli 5412, Escherichia coli EC96038, Escherichia coli CB7326, Escherichia coli MA6, Escherichia coli TT12B, Escherichia coli PA45, Escherichia coli PA49, Escherichia coli PA23, Escherichia coli PA4, Escherichia coli FRIK2001, Escherichia coli NE037, Escherichia coli NE1487, Escherichia coli FRIK1997, Escherichia coli FRIK1999, Escherichia coli FDA504, Escherichia coli FDA507, Escherichia coli FDA506, Escherichia coli PA34, Escherichia coli FRIK920, Escherichia coli PA7, Escherichia coli EC1863, Escherichia coli EC1845, Escherichia coli EC1734, Escherichia coli EC1738, Escherichia coli EC4448, Escherichia coli EC4437, Escherichia coli EC4436, Escherichia coli EC4439, Escherichia coli EC4402, Escherichia coli EC4013, Escherichia coli EC4422, Escherichia coli EC4421, Escherichia coli TW14301, Escherichia coli TW14313, Escherichia coli EC4196, Escherichia coli EC4203, Escherichia coli TW09195, Escherichia coli TW10119, Escherichia coli TW09109, Escherichia coli TW09098, Escherichia coli TW10246, Escherichia coli TW11039, Escherichia coli TW07945, Escherichia coli TW06591, Escherichia coli PA42, Escherichia coli PA41, Escherichia coli PA39, Escherichia coli PA40, Escherichia coli PA33, Escherichia coli PA32, Escherichia coli PA31, Escherichia coli PA28, Escherichia coli PA25, Escherichia coli PA24, Escherichia coli PA22, Escherichia coli PA15, Escherichia coli PA14, Escherichia coli PA10, Escherichia coli PA9, Escherichia coli PA5, Escherichia coli PA3, Escherichia coli FRIK1990, Escherichia coli 93-001, Escherichia coli FRIK1985, Escherichia coli FDA517, Escherichia coli FDA505, Escherichia coli FRIK1996, Escherichia coli Xuzhou21, Escherichia coli DEC4F, Escherichia coli DEC5B, Escherichia coli DEC4D, Escherichia coli DEC4E, Escherichia coli DEC4C, Escherichia coli DEC4B, Escherichia coli DEC4A, Escherichia coli DEC3F, Escherichia coli DEC3E, Escherichia coli DEC3D, Escherichia coli DEC3B, Escherichia coli DEC3C, Escherichia coli DEC3A, Escherichia coli O157:H7 str. 1044, Escherichia coli O157:H7 str. 1125, Escherichia coli O157:H7 str. LSU-61, Escherichia coli O55:H7 str. 3256-97, Escherichia coli O157:H- str. H 2687, Escherichia coli O157:H- str. 493-89, Escherichia coli O157:H7 str. G5101, Escherichia coli O157:H7 str. EC1212, Escherichia coli O157:H7 str. TW14359, Escherichia coli O157:H7 str. TW14588, Escherichia coli O157:H7 str. EC4115, Escherichia coli O157:H7 str. EC4042, Escherichia coli O157:H7 str. EC4045, Escherichia coli O157:H7 str. EC4206, Escherichia coli O157:H7 str. EC508, Escherichia coli O157:H7 str. EC869, Escherichia coli O157:H7 str. EC4501, Escherichia coli O157:H7 str. EC4486, Escherichia coli O157:H7 str. EC4401, Escherichia coli O157:H7 str. EC4076, Escherichia coli O157:H7 str. EC4113, Escherichia coli O157:H7 str. EC4196 Bacteria UP000036210, UP000034479, UP000030908, UP000028484, UP000028188, UP000023979, UP000023880, UP000024046, UP000024144, UP000024187, UP000024025, UP000024221, UP000024305, UP000024157, UP000024108, UP000024223, UP000023856, UP000024040, UP000023988, UP000023950, UP000023823, UP000023872, UP000023862, UP000023967, UP000024085, UP000024266, UP000024225, UP000024036, UP000024010, UP000024287, UP000024002, UP000024182, UP000024062, UP000023805, UP000024334, UP000024228, UP000024024, UP000024082, UP000024285, UP000023865, UP000024087, UP000024071, UP000023835, UP000024303, UP000023964, UP000024326, UP000023902, UP000024272, UP000023946, UP000023922, UP000024216, UP000024007, UP000024167, UP000024135, UP000023901, UP000024246, UP000024130, UP000023941, UP000024209, UP000023811, UP000023983, UP000023848, UP000024276, UP000024196, UP000023830, UP000024011, UP000023877, UP000023981, UP000023962, UP000024137, UP000024095, UP000023896, UP000024051, UP000024146, UP000023934, UP000024227, UP000023894, UP000023971, UP000024132, UP000024294, UP000024065, UP000024086, UP000023943, UP000024304, UP000024115, UP000024286, UP000023888, UP000024180, UP000024066, UP000024323, UP000024136, UP000024124, UP000024290, UP000023824, UP000018829, UP000016422, UP000016428, UP000016267, UP000016130, UP000016126, UP000016244, UP000016075, UP000016382, UP000016319, UP000016419, UP000016274, UP000016384, UP000016077, UP000016391, UP000016260, UP000016270, UP000016271, UP000016108, UP000016276, UP000016405, UP000016098, UP000016242, UP000016435, UP000016280, UP000016287, UP000016099, UP000016110, UP000016398, UP000016140, UP000016375, UP000016038, UP000016381, UP000016087, UP000016243, UP000016012, UP000015984, UP000016316, UP000016292, UP000016073, UP000016060, UP000016044, UP000017026, UP000016363, UP000016303, UP000016349, UP000016383, UP000016360, UP000016150, UP000011536, UP000011631, UP000011584, UP000011552, UP000011600, UP000011503, UP000011588, UP000011624, UP000011640, UP000011520, UP000011582, UP000011516, UP000011641, UP000011652, UP000011542, UP000011620, UP000011587, UP000011525, UP000011678, UP000011580, UP000011756, UP000011653, UP000010417, UP000010462, UP000010193, UP000010167, UP000010178, UP000010165, UP000010174, UP000010186, UP000010191, UP000010171, UP000010185, UP000010172, UP000010181, UP000010168, UP000010187, UP000010189, UP000010177, UP000010184, UP000010176, UP000010180, UP000010190, UP000010170, UP000010188, UP000010192, UP000007983, UP000007971, UP000007988, UP000008161, UP000007970, UP000007973, UP000007828, UP000007985, UP000007829, UP000008162, UP000007372, UP000007121, UP000007361, UP000006789, UP000007357, UP000007370, UP000007120, UP000006788, UP000007376, UP000007375, UP000006785, UP000006778, UP000006780, UP000007128, UP000007119, UP000007117, UP000006771, UP000006951, UP000007821, UP000006774, UP000006775, UP000006670, UP000007352, UP000007122, UP000007133, UP000007362, UP000007359, UP000007369, UP000007134, UP000006782, UP000006770, UP000007363, UP000007355, UP000007379, UP000006779, UP000007368, UP000007818, UP000007118, UP000007125, UP000006203, UP000004228, UP000005607, UP000002988, UP000003337, UP000003298, UP000003284, UP000003501, UP000005171, UP000003407, UP000003487, UP000004101, UP000004734, UP000003920, UP000005616, UP000004159, UP000004006, UP000004238, UP000003080, UP000004415, UP000004907, UP000003615, UP000003722, UP000005198, UP000004490, UP000002962, UP000003199, UP000004628, UP000004406, UP000002961, UP000004161, UP000003193, UP000005611, UP000004012, UP000004174, UP000003707, UP000004329, UP000005487, UP000003145, UP000004831, UP000003262, UP000005927, UP000006439, UP000005375, UP000003993, UP000003575, UP000003047, UP000002870, UP000004886, UP000005701, UP000004838, UP000005166, UP000003871, UP000004502, UP000003663, UP000004340, UP000004453, UP000004977, UP000005472, UP000004747, UP000004630, UP000004025, UP000005071, UP000003371, UP000003097, UP000004043, UP000003632, UP000003216, UP000003002, UP000002056, UP000001326, UP000001737, UP000004442, UP000004231, UP000004385, UP000004050, UP000004641, UP000004513, UP000003896, UP000003685, UP000003596, UP000005058, UP000003830 15834171, 447199653, 821093202, 816356693, 814576464, 814571501, 769023147, 762043563, 761656700, 734591905, 667694855, 666006764, 612257694, 612246948, 607831817, 607825187, 607801380, 607800831, 607778069, 607705391, 607694608, 607681290, 607636521, 607623935, 607614872, 607613025, 607612288, 607604607, 607602462, 607597905, 607590488, 607580584, 607580168, 607577378, 607566865, 607557345, 607549481, 607545338, 607543660, 607533956, 607532282, 607524650, 607523115, 607515365, 607512463, 607509494, 607497170, 607483906, 607479601, 607479248, 607474162, 607460401, 607449606, 607446745, 607445792, 607440392, 607434576, 607423323, 607420962, 607410301, 607407974, 607405807, 607392035, 606892077, 606890873, 606890680, 606805913, 606719917, 606711143, 606703661, 606701763, 606695729, 606690502, 606683812, 606676065, 606672334, 606667624, 606665532, 606648266, 606631251, 606625113, 606624927, 606619767, 606608763, 606608547, 606600193, 606594156, 606592715, 606585401, 606577632, 606577489, 606565504, 606564985, 606564345, 606552521, 606549052, 606546072, 606532166, 606524804, 606509493, 606504633, 567044254, 537068274, 537060134, 537054833, 537052747, 537044042, 537040212, 537029156, 537016545, 537011708, 537004177, 537000440, 536995585, 536985438, 536980300, 536979646, 536969197, 536964020, 536960566, 536950710, 536946556, 536945197, 536931914, 536931246, 536927130, 536914991, 536914530, 536910452, 536898167, 536894081, 536885010, 536880553, 536872381, 536865255, 536856448, 536851696, 536850742, 536841425, 536833797, 536827938, 536825623, 536818070, 536808094, 536807883, 536802474, 536795298, 536783837, 536782409, 536782368, 444666360, 444658735, 444656702, 444650923, 444636473, 444634740, 444626052, 444619770, 444618328, 444611977, 444602826, 444602797, 444588905, 444587575, 444575218, 444571709, 444568516, 444555363, 444553884, 444545007, 444535892, 444534679, 429250902, 429250405, 427325609, 427324598, 427314897, 427310033, 427307221, 427296898, 427295574, 427288683, 427280121, 427274399, 427272790, 427257227, 427257028, 427255491, 427241808, 427237555, 427237435, 427223723, 427221027, 427204130, 427201060, 427201013, 408608244, 408598646, 408593025, 408588100, 408578140, 408575452, 408562939, 408545377, 408544566, 408544320, 408341329, 408333892, 408322480, 408321069, 408315464, 408304075, 408302925, 408287929, 408281872, 408273729, 408270779, 408262572, 408255890, 408251480, 408242636, 408236955, 408234490, 408223292, 408209935, 408179961, 408176750, 408170020, 408156936, 408151770, 408143494, 408136205, 408134572, 408124633, 408118352, 408112231, 408105446, 408100524, 408094303, 408088026, 408079983, 408074828, 408063617, 408063223, 408062696, 390915465, 390914699, 390905460, 390897389, 390891005, 390889851, 390879985, 390874621, 390866211, 390862269, 390857868, 390847414, 390842389, 390840386, 390827197, 390822149, 390821052, 390813305, 390805490, 390799633, 390796678, 390794385, 390785201, 390778962, 390764413, 390761525, 390757473, 390755287, 390740865, 390737107, 390736352, 390723812, 390717701, 390716503, 390711002, 390696954, 390695707, 390691562, 390680462, 390677010, 390673683, 390658851, 390656381, 390655577, 390637957, 390636960, 390636803, 386798674, 377967779, 377958263, 377952176, 377943349, 377935400, 377925859, 377922715, 377916465, 377906122, 377902872, 377902842, 377901363, 377890728, 326347594, 326347155, 320665893, 320655131, 320649798, 320644479, 320639085, 320190909, 254595392, 217321133, 209751746, 209751742, 209751740, 209751738, 209160639, 208739162, 208733839, 208727574, 189379141, 189370176, 189365463, 189359750, 189354604, 189001709, 188014034, 187767367, 238065979, 21759453, 13364393 KKY45067.1, KKK30473.1, KKF80354.1, KKF76361.1, KJJ44468.1, KIZ08886.1, KIY25574.1, AJA29106.1, AIG71464.1, AIF96621.1, EZQ51489.1, EZQ40923.1, EZF09603.1, EZF03064.1, EZE81173.1, EZE80642.1, EZE58560.1, EZD88554.1, EZD78116.1, EZD65330.1, EZD22209.1, EZD10105.1, EZD01204.1, EZC99427.1, EZC98731.1, EZC91176.1, EZC89071.1, EZC84640.1, EZC77384.1, EZC67606.1, EZC67196.1, EZC64482.1, EZC54110.1, EZC44904.1, EZC37297.1, EZC33259.1, EZC31620.1, EZC22098.1, EZC20465.1, EZC12987.1, EZC11499.1, EZC03928.1, EZC01095.1, EZB98224.1, EZB86112.1, EZB73202.1, EZB68980.1, EZB68648.1, EZB63669.1, EZB50242.1, EZB39649.1, EZB36868.1, EZB35947.1, EZB30833.1, EZB25112.1, EZB14258.1, EZB11994.1, EZB01753.1, EZA99483.1, EZA97401.1, EZA84119.1, EYZ26467.1, EYZ25475.1, EYZ25330.1, EYY45052.1, EYX63979.1, EYX55641.1, EYX48501.1, EYX46742.1, EYX40985.1, EYX36026.1, EYX29763.1, EYX22333.1, EYX18825.1, EYX14455.1, EYX12417.1, EYW95944.1, EYW79923.1, EYW74062.1, EYW73886.1, EYW69127.1, EYW58626.1, EYW58446.1, EYW50592.1, EYW44827.1, EYW43524.1, EYW36644.1, EYW29215.1, EYW29084.1, EYW17713.1, EYW17217.1, EYW16604.1, EYW05391.1, EYW02075.1, EYV99347.1, EYV86220.1, EYV79449.1, EYV64959.1, EYV60231.1, ETJ80794.1, ERE37636.1, ERE30060.1, ERE24997.1, ERE23029.1, ERE14913.1, ERE11279.1, ERE01033.1, ERD89175.1, ERD84599.1, ERD77491.1, ERD73893.1, ERD69421.1, ERD60076.1, ERD56327.1, ERD55719.1, ERD46057.1, ERD41108.1, ERD37845.1, ERD28590.1, ERD24616.1, ERD23286.1, ERD10739.1, ERD10100.1, ERD06166.1, ERC94774.1, ERC94335.1, ERC90466.1, ERC79003.1, ERC75179.1, ERC66742.1, ERC62540.1, ERC54625.1, ERC47744.1, ERC39193.1, ERC34569.1, ERC33628.1, ERC24598.1, ERC17471.1, ERC11975.1, ERC09748.1, ERC02520.1, ERB92894.1, ERB92691.1, ERB87438.1, ERB80493.1, ERB69363.1, ERB67965.1, ERB67928.1, ELW38434.1, ELW31173.1, ELW29222.1, ELW23736.1, ELW09870.1, ELW08195.1, ELV99858.1, ELV93796.1, ELV92414.1, ELV86288.1, ELV77555.1, ELV77527.1, ELV64264.1, ELV63004.1, ELV51467.1, ELV48178.1, ELV45189.1, ELV32832.1, ELV31476.1, ELV23971.1, ELV15941.1, ELV14883.1, EKY35540.1, EKY35065.1, EKW87045.1, EKW86066.1, EKW76919.1, EKW72304.1, EKW69702.1, EKW59943.1, EKW58675.1, EKW52298.1, EKW44500.1, EKW39057.1, EKW37509.1, EKW23359.1, EKW23169.1, EKW21755.1, EKW09229.1, EKW05089.1, EKW04976.1, EKV92453.1, EKV89907.1, EKV74416.1, EKV71460.1, EKV71419.1, EKK81645.1, EKK72598.1, EKK67366.1, EKK62701.1, EKK53677.1, EKK51122.1, EKK39086.1, EKK22812.1, EKK22017.1, EKK21778.1, EKJ55783.1, EKJ48811.1, EKJ38465.1, EKJ37120.1, EKJ31780.1, EKJ21513.1, EKJ20401.1, EKJ06769.1, EKJ01240.1, EKI93771.1, EKI90945.1, EKI83507.1, EKI77310.1, EKI73210.1, EKI65203.1, EKI59823.1, EKI57504.1, EKI47075.1, EKI34510.1, EKI06607.1, EKI03585.1, EKH97251.1, EKH85121.1, EKH80249.1, EKH72791.1, EKH65954.1, EKH64396.1, EKH55291.1, EKH49495.1, EKH43900.1, EKH37614.1, EKH33023.1, EKH27339.1, EKH21421.1, EKH14084.1, EKH09081.1, EKG98107.1, EKG97719.1, EKG97198.1, EIP73979.1, EIP73234.1, EIP64403.1, EIP56718.1, EIP50648.1, EIP49554.1, EIP40704.1, EIP35724.1, EIP28186.1, EIP24469.1, EIP20292.1, EIP10957.1, EIP06240.1, EIP04427.1, EIO92975.1, EIO88287.1, EIO87267.1, EIO79942.1, EIO72435.1, EIO66772.1, EIO63946.1, EIO61682.1, EIO52755.1, EIO46712.1, EIO33623.1, EIO30813.1, EIO26952.1, EIO24833.1, EIO11980.1, EIO08417.1, EIO07689.1, EIN96392.1, EIN90478.1, EIN89301.1, EIN83995.1, EIN71390.1, EIN70219.1, EIN66299.1, EIN56306.1, EIN53086.1, EIN49910.1, EIN36634.1, EIN34261.1, EIN33504.1, EIN17486.1, EIN16520.1, EIN16374.1, AFJ31708.1, EHV31182.1, EHV21779.1, EHV15774.1, EHV07069.1, EHU99199.1, EHU89796.1, EHU86696.1, EHU80548.1, EHU70377.1, EHU67173.1, EHU67144.1, EHU65683.1, EHU55184.1, EGD71316.1, EGD70885.1, EFX32924.1, EFX23087.1, EFX18319.1, EFX13542.1, EFX08725.1, EFW65559.1, ACT74753.1, EEC29557.1, ACI74180.1, ACI74178.1, ACI74177.1, ACI74176.1, ACI38072.1, EDZ86844.1, EDZ82526.1, EDZ77175.1, EDU97557.1, EDU88592.1, EDU83879.1, EDU78169.1, EDU73023.1, EDU70695.1, EDU52156.1, EDU31211.1 NP_312944.1, WP_001276909.1 Q8X6X9, B5Z090 THIC_ECO57, THIC_ECO5E Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 96386, 7328454, 5000775, 4962569, 5006794, 5013826, 4984144, 7566676, 4994088, 5015615, 4981037, 4947061, 10470842, 4956347, 4974716, 6017791 fig|1005440.3.peg.4697, fig|1005527.3.peg.4707, fig|1005432.3.peg.4017, fig|1005513.3.peg.4453, fig|1005536.3.peg.5195, fig|1005545.3.peg.5035, fig|1005531.3.peg.4718, fig|1005473.3.peg.5065, fig|1005561.3.peg.4857, fig|1005544.3.peg.4872, fig|1005472.3.peg.5014, fig|1005554.3.peg.4828, fig|1169862.3.peg.4948, fig|1005493.3.peg.5010, fig|1005515.3.peg.4726, fig|502346.5.peg.1677, fig|1005411.3.peg.4889, fig|1051348.3.peg.4970, fig|544404.4.peg.5127, fig|1005482.3.peg.4990, fig|1005525.3.peg.4646, fig|1317130.3.peg.4636, fig|1005541.3.peg.4842, fig|1005460.3.peg.4864, fig|1005415.3.peg.4925, fig|1005500.3.peg.4681, fig|868153.3.peg.4969, fig|1005404.3.peg.4943, fig|1005526.3.peg.4763, fig|741093.3.peg.4993, fig|1005498.3.peg.4889, fig|1005516.3.peg.4860, fig|1005422.3.peg.4928, fig|1005492.3.peg.5027, fig|1005524.3.peg.4750, fig|1005401.3.peg.4768, fig|1005528.3.peg.4955, fig|868146.3.peg.5517, fig|1005537.3.peg.4928, fig|1081887.3.peg.4860, fig|1005507.3.peg.4775, fig|868154.3.peg.16, fig|444454.5.peg.4024, fig|868149.3.peg.4446, fig|1005398.3.peg.4912, fig|1005522.3.peg.5613, fig|1005480.3.peg.5087, fig|1005484.3.peg.5220, fig|1005419.3.peg.4818, fig|1005509.3.peg.4865, fig|1005505.3.peg.5046, fig|1005519.3.peg.4928, fig|997824.3.peg.514, fig|1005471.3.peg.4780, fig|1005517.3.peg.14, fig|444451.5.peg.4840, fig|1005476.3.peg.4982, fig|444449.5.peg.3480, fig|1005549.3.peg.5044, fig|702432.3.peg.991, fig|1005534.3.peg.4901, fig|1005502.3.peg.4779, fig|1005403.3.peg.4776, fig|1005521.3.peg.4534, fig|1005475.3.peg.4934, fig|478006.5.peg.4863, fig|1005510.3.peg.5083, fig|1005489.3.peg.5081, fig|702436.3.peg.4389, fig|868143.3.peg.4140, fig|1005407.3.peg.4477, fig|1005553.3.peg.5051, fig|1005538.3.peg.4898, fig|926028.3.peg.2932, fig|1005466.3.peg.5134, fig|1005421.3.peg.4903, fig|1005434.3.peg.4813, fig|1005477.3.peg.5082, fig|1005412.3.peg.5006, fig|570506.3.peg.2920, fig|1005486.3.peg.4974, fig|1005455.3.peg.5075, fig|1005495.3.peg.4926, fig|1005469.3.peg.4781, fig|702434.4.peg.1088, fig|868148.3.peg.5112, fig|1005501.3.peg.4928, fig|1005496.3.peg.5062, fig|868147.3.peg.5219, fig|1005499.3.peg.4712, fig|83334.1.peg.4893, fig|1005542.3.peg.4857, fig|478004.5.peg.5173, fig|1005559.3.peg.4881, fig|1005433.3.peg.4619, fig|444453.5.peg.1874, fig|1005418.3.peg.4730, fig|1005470.3.peg.5047, fig|444450.8.peg.5317, fig|478008.5.peg.5371, fig|869673.3.peg.3022, fig|1005463.3.peg.4755, fig|1005490.3.peg.4801, fig|1240385.3.peg.4684, fig|1005399.3.peg.4767, fig|1005396.3.peg.4972, fig|1005410.3.peg.4921, fig|1051350.3.peg.4622, fig|702433.3.peg.4354, fig|997825.3.peg.130, fig|1005546.3.peg.4896, fig|1005497.3.peg.5318, fig|1005405.3.peg.4887, fig|1005540.3.peg.4725, fig|1005539.3.peg.4805, fig|1005532.3.peg.4806, fig|926027.3.peg.2868, fig|702430.3.peg.3743, fig|1005461.3.peg.5133, fig|1005474.3.peg.5340, fig|1005494.3.peg.4987, fig|1005436.3.peg.4596, fig|1005430.3.peg.4716, fig|868156.3.peg.5470, fig|1005503.3.peg.4833, fig|1005487.3.peg.4802, fig|868144.3.peg.113, fig|1005508.3.peg.5312, fig|1005529.3.peg.5067, fig|1005423.3.peg.4956, fig|1005483.3.peg.5355, fig|926029.3.peg.3040, fig|1005518.3.peg.4632, fig|1051351.3.peg.4816, fig|1005547.3.peg.4755, fig|868150.3.peg.5075, fig|637388.3.peg.4373, fig|1005441.3.peg.5022, fig|386585.9.peg.5142, fig|1005408.3.peg.5037, fig|1005512.3.peg.4716, fig|444448.5.peg.2236, fig|1005439.3.peg.4937, fig|1005424.3.peg.4829, fig|1005506.3.peg.4650, fig|926026.3.peg.2838, fig|1005485.3.peg.5220, fig|1005416.3.peg.4925, fig|1051346.3.peg.4713, fig|1005413.3.peg.4953, fig|1005438.3.peg.4453, fig|1005437.3.peg.5034, fig|1005523.3.peg.4765, fig|702431.3.peg.3657, fig|1005555.3.peg.5017, fig|1005543.3.peg.5121, fig|1005530.3.peg.4778, fig|1005481.3.peg.4970, fig|1005535.3.peg.5307, fig|1005557.3.peg.5240, fig|562.371.peg.380, fig|1051352.3.peg.5143, fig|1005491.3.peg.5325, fig|1005397.3.peg.4878, fig|444447.5.peg.2402, fig|1005479.3.peg.5420, fig|1005511.3.peg.5099, fig|1005402.3.peg.4955, fig|1005488.3.peg.4836, fig|1005478.3.peg.4732, fig|1005467.3.peg.4781, fig|868145.3.peg.5367, fig|941435.3.peg.2339, fig|1051347.3.peg.4807, fig|1005450.3.peg.5000, fig|1005533.3.peg.5028, fig|1005406.3.peg.5016, fig|444452.5.peg.4920, fig|1005520.3.peg.4595, fig|1005420.3.peg.4630, fig|1005551.3.peg.4756, fig|1005414.3.peg.4926, fig|1005452.3.peg.5017, fig|1005504.3.peg.4794, fig|478007.5.peg.1200, fig|1051349.3.peg.4780, fig|478005.5.peg.5061, fig|1005548.3.peg.4605, fig|926032.3.peg.2880 626 631 yes 437943 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 422289 Beggiatoa sp. PS Bacteria UP000003255 152073764 EDN70700.1 626 628 yes 437944 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 391574 Vibrionales bacterium SWAT-3 Bacteria UP000004912 495496886, 145962390 EDK27670.1 WP_008221543.1 fig|391574.12.peg.3416 640 649 yes 437945 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 70864, 398579 Shewanella pealeana, Shewanella pealeana ATCC 700345 Bacteria UP000002608 501105902, 157847204, 189030299 ABV87703.1 WP_012155617.1 A8H566 THIC_SHEPA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7160486 fig|398579.3.peg.2050 657 667 yes 437946 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 349106 Psychrobacter sp. PRwf-1 Bacteria UP000001993 500601936, 148573153 ABQ95212.1 WP_011961484.1 fig|349106.5.peg.2385 658 666 yes 437947 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 816, 585543, 411479 Bacteroides sp. D20, Bacteroides uniformis ATCC 8492 Bacteria UP000005079, UP000004110 492378579, 270272793, 156862237 EFA18656.1, EDO55668.1 WP_005825547.1 fig|585543.3.peg.3390, fig|411479.10.peg.957 560 560 yes 437948 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 404589 Anaeromyxobacter sp. Fw109-5 Bacteria UP000006382 501045142, 152028601, 166228009 ABS26369.1 WP_012096950.1 A7HCC3 THIC_ANADF Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} fig|404589.10.peg.2273 448 468 yes 437949 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1513 Clostridium tetani Bacteria UP000029689 499411623, 747252787, 734999029, 693310231, 693305720 KIG19901.1, KHO36537.1, KGI43365.1, KGI38931.1 WP_011099090.1 fig|212717.1.peg.711 438 438 yes 437950 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 152480, 398577 Burkholderia ambifaria, Burkholderia ambifaria MC40-6 Bacteria UP000001680 501331846, 171992677, 238692859 ACB63596.1 WP_012363481.1 B1YW60 THIC_BURA4 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7155946, 6044596, 6066206, 1917151 fig|398577.6.peg.1131 642 643 yes 437951 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 95486, 406425 Burkholderia cenocepacia, Burkholderia cenocepacia MC0-3 Bacteria UP000065887, UP000002169 501285183, 169815787, 238688613 ACA90370.1 WP_012328201.1 B1JYX0 THIC_BURCC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7215930 fig|406425.4.peg.1230 642 643 yes 437952 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1421, 1400869, 444177 Lysinibacillus sphaericus, Lysinibacillus sphaericus CBAM5, Lysinibacillus sphaericus C3-41 Bacteria UP000028424, UP000023555, UP000002164 501249467, 584604150, 168990795 EWH30381.1, ACA38335.1 WP_012292485.1 fig|444177.5.peg.847 592 592 yes 437953 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1491, 445337 Clostridium botulinum, Clostridium botulinum C str. Eklund Bacteria UP000030128, UP000003482 489460140, 169295589 EDS77722.1 WP_003365355.1 fig|445337.5.peg.1024 437 437 yes 437954 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 456481 Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' Bacteria UP000001847 167780100 ABZ98398.1 fig|355278.4.peg.2325, fig|456481.4.peg.2313 518 524 yes 437955 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 60961, 392500 Shewanella woodyi, Shewanella woodyi ATCC 51908 Bacteria UP000002168 501282191, 169812285, 238688667 ACA86869.1 WP_012325209.1 B1KHI4 THIC_SHEWM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7100887 fig|392500.3.peg.2564 641 652 yes 437956 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 303, 390235 Pseudomonas putida, Pseudomonas putida W619 Bacteria UP000054813, UP000000720 501273488, 169761875, 229558535 ACA75191.1 WP_012316506.1 B1JAG3 THIC_PSEPW Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7078216 fig|390235.3.peg.4685 627 628 yes 437957 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 186802, 649757, 411484, 1262984, 649756 Eubacterium hadrum DSM 3319, Clostridium sp. SS2/1, Lachnospiraceae bacterium CAG:25, Eubacterium hadrum Bacteria, Environmental samples UP000010409, UP000004518, UP000018334, UP000008960 495669318, 429179175, 167709738, 524270140, 291560233 EKY20435.1, EDS20317.1 WP_008393897.1 fig|411484.7.peg.2504, fig|245018.3.peg.2446, fig|649757.3.peg.2064 433 433 yes 437958 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 186490, 374463 Candidatus Baumannia cicadellinicola, Baumannia cicadellinicola str. Hc (Homalodisca coagulata) Bacteria UP000067325, UP000002427 499839518, 94219777, 166228014 ABF13936.1 WP_011520252.1 Q1LU45 THIC_BAUCH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2023033 fig|374463.4.peg.42 615 622 yes 437959 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 68909, 319795 Deinococcus geothermalis, Deinococcus geothermalis DSM 11300 Bacteria UP000002431 499850312, 94556305, 166228030 ABF46219.1 WP_011531046.1 Q1IX15 THIC_DEIGD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1845167, 695335 fig|68909.1.peg.134, fig|319795.16.peg.2519 605 609 yes 437960 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 43771, 504474 Corynebacterium urealyticum, Corynebacterium urealyticum DSM 7109 Bacteria UP000001727 501328716, 171852087 WP_012360351.1 fig|504474.3.peg.1099 599 606 yes 437961 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 48736, 402626 Ralstonia pickettii 12J Bacteria UP000002566 501405245, 187727596 ACD28761.1 WP_012436811.1 fig|402626.5.peg.4778 633 635 yes 437962 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 106589, 1249621, 266264 Cupriavidus sp. HMR-1, Cupriavidus metallidurans CH34 Bacteria UP000010442, UP000002429 495918049, 429502179, 93352959, 166228059 ELA00496.1, ABF07048.1 WP_008642628.1 Q1LS28 THIC_CUPMC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1772566 fig|1249621.3.peg.975, fig|266264.4.peg.567 623 625 yes 437963 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 46506, 449673 Bacteroides stercoris, Bacteroides stercoris ATCC 43183 Bacteria UP000056419, UP000004713 491888928, 167699348 EDS15927.1 WP_005654093.1 fig|449673.7.peg.1190 562 562 yes 437964 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 1133852, 1048254, 745156, 1444270, 1444113, 1444248, 1444235, 1444262, 1444260, 1444177, 1444230, 1446547, 1446729, 1446751, 1446512, 1444060, 1444119, 1438678, 1446510, 1446508, 1446715, 1446509, 1446511, 1444078, 1444105, 1446722, 1446721, 1446720, 1446719, 1446718, 1446717, 1446716, 1446714, 1446713, 1446733, 1446730, 1446732, 1446731, 1446728, 1446727, 1446725, 1446726, 1446723, 1446724, 1446710, 1446711, 1446549, 1446517, 1446516, 1446580, 1446753, 1446764, 1446542, 1446541, 1446540, 1446539, 1446538, 1446537, 1446535, 1446536, 1446533, 1446534, 1446498, 1446500, 1446513, 1446514, 1446545, 1446750, 1446763, 1446522, 1446521, 1446523, 1446735, 1446524, 1446525, 1446526, 1446527, 1446528, 1446529, 1446530, 1446532, 1446531, 1446507, 1446752, 1446548, 1446515, 1446502, 1446518, 1446519, 1446734, 1446520, 1404262, 1405292, 1405293, 1281192, 1268977, 1268978, 1281235, 1333536, 1281240, 1281238, 1281227, 1281212, 1281072, 1125639, 1125640, 1125638, 1125635, 1116144, 1116146, 1116145, 1116142, 1116143, 1116149, 1116150, 1116148, 1116147, 1116025, 1116024, 1116141, 1116139, 1116015, 1116124, 1090928, 1090927, 1181749, 1182655, 1182710, 1182663, 1181756, 1240759, 1240779, 1240767, 1240778, 1240766, 1240765, 1240764, 1240763, 1240762, 1240761, 1240758, 1240760, 1240776, 1240777, 1240775, 1240774, 1240773, 1240772, 1240771, 1240770, 1240769, 1240768, 1232154, 1232150, 1232151, 1005550, 1133853, 1134782, 1163738, 1165952, 1165939, 1165947, 1165950, 1165942, 1165953, 1165944, 752790, 1165951, 1165949, 1163391, 1165943, 1165945, 1165946, 869695, 869682, 869681, 869678, 868201, 868185, 868182, 868181, 868183, 868180, 868179, 868178, 868177, 868174, 868176, 868175, 868173, 868172, 868171, 868170, 1068621, 1068620, 1068619, 1068618, 1068617, 1068616, 1068615, 1068614, 1048334, 1048266, 1048265, 1048256, 754079, 1040638, 1042803, 656374, 670904, 670893, 481805, 244319, 585396, 573235, 585055 Escherichia coli, Escherichia coli O104:H4 str. 2011C-3493, Escherichia coli O104:H4 str. C227-11, Escherichia coli 1303, Escherichia coli 7-233-03_S4_C3, Escherichia coli 4-203-08_S1_C3, Escherichia coli 3-020-07_S4_C2, Escherichia coli 2-316-03_S4_C2, Escherichia coli 2-177-06_S4_C3, Escherichia coli 2-052-05_S4_C3, Escherichia coli 2-052-05_S3_C3, Escherichia coli 2-052-05_S4_C2, Escherichia coli O118:H16 str. 07-4255, Escherichia coli O26:H11 str. 2011C-3274, Escherichia coli O69:H11 str. 07-3763, Escherichia coli O111:NM str. 01-3076, Escherichia coli 4-203-08_S1_C1, Escherichia coli 2-052-05_S3_C1, Escherichia coli BIDMC 74, Escherichia coli O111:H8 str. 2011C-3453, Escherichia coli O111:H8 str. 2009C-4126, Escherichia coli O26:H1 str. 2009C-4747, Escherichia coli O111:H8 str. 2009EL-2169, Escherichia coli O111:NM str. 2010C-3053, Escherichia coli 1-176-05_S1_C2, Escherichia coli 1-176-05_S1_C3, Escherichia coli O26:H1 str. 2010C-4244, Escherichia coli O26:H1 str. 2010C-3902, Escherichia coli O26:H1 str. 2010C-3871, Escherichia coli O26:H1 str. 2010C-3472, Escherichia coli O26:H1 str. 2010C-3051, Escherichia coli O26:H1 str. 2009C-4826, Escherichia coli O26:H1 str. 2009C-4760, Escherichia coli O26:H1 str. 2009C-3996, Escherichia coli O26:H1 str. 2009C-3689, Escherichia coli O26:H1 str. 2011C-3655, Escherichia coli O26:H1 str. 2011C-3282, Escherichia coli O26:H1 str. 2011C-3506, Escherichia coli O26:H1 str. 2011C-3387, Escherichia coli O26:H1 str. 2011C-3270, Escherichia coli O26:H1 str. 2010EL-1699, Escherichia coli O26:H1 str. 2010C-4834, Escherichia coli O26:H1 str. 2010C-5028, Escherichia coli O26:H1 str. 2010C-4430, Escherichia coli O26:H1 str. 2010C-4819, Escherichia coli O26:H1 str. 03-3500, Escherichia coli O26:H1 str. 06-3464, Escherichia coli O118:H16 str. 2009C-4446, Escherichia coli O111:NM str. 2009C-4052, Escherichia coli O111:NM str. 2009C-4006, Escherichia coli O123:H11 str. 2009C-3307, Escherichia coli O69:H11 str. 08-4661, Escherichia coli O91:H14 str. 2009C-3227, Escherichia coli O111:NM str. K6915, Escherichia coli O111:NM str. K6908, Escherichia coli O111:NM str. K6904, Escherichia coli O111:NM str. K6898, Escherichia coli O111:NM str. K6897, Escherichia coli O111:NM str. K6895, Escherichia coli O111:NM str. K6728, Escherichia coli O111:NM str. K6890, Escherichia coli O111:NM str. K6722, Escherichia coli O111:NM str. K6723, Escherichia coli O111:H8 str. F6627, Escherichia coli O26:H11 str. 05-3646, Escherichia coli O111:NM str. 03-3484, Escherichia coli O111:NM str. 04-3211, Escherichia coli O118:H16 str. 06-3256, Escherichia coli O69:H11 str. 06-3325, Escherichia coli O91:H14 str. 06-3691, Escherichia coli O111:NM str. 2010C-4622, Escherichia coli O111:NM str. 2010C-4592, Escherichia coli O111:NM str. 2010C-4715, Escherichia coli O26:NM str. 2010C-4788, Escherichia coli O111:NM str. 2010C-4735, Escherichia coli O111:NM str. 2010C-4746, Escherichia coli O111:NM str. 2010C-4799, Escherichia coli O111:NM str. 2010C-4818, Escherichia coli O111:NM str. 2011C-3170, Escherichia coli O111:NM str. 2011C-3362, Escherichia coli O111:NM str. 2011C-3573, Escherichia coli O111:NM str. 2011C-3679, Escherichia coli O111:NM str. 2011C-3632, Escherichia coli O104:H4 str. 2011EL-1675A, Escherichia coli O69:H11 str. 07-4281, Escherichia coli O118:H16 str. 08-3651, Escherichia coli O111:NM str. 08-4487, Escherichia coli O103:H11 str. 2010C-3214, Escherichia coli O111:NM str. 2010C-3977, Escherichia coli O111:NM str. 2010C-4086, Escherichia coli O26:NM str. 2010C-4347, Escherichia coli O111:NM str. 2010C-4221, Escherichia coli ATCC BAA-2193, Escherichia coli ATCC BAA-2196, Escherichia coli ATCC BAA-2209, Escherichia coli UMEA 3148-1, Escherichia coli 113302, Escherichia coli 113303, Escherichia coli UMEA 3292-1, Escherichia coli 95NR1, Escherichia coli UMEA 3318-1, Escherichia coli UMEA 3314-1, Escherichia coli UMEA 3240-1, Escherichia coli UMEA 3199-1, Escherichia coli HVH 139 (4-3192644), Escherichia coli P0298942.3, Escherichia coli P0298942.4, Escherichia coli MP020980.1, Escherichia coli 2733950, Escherichia coli P0298942.7, Escherichia coli P0298942.9, Escherichia coli P0298942.8, Escherichia coli P0298942.2, Escherichia coli P0298942.6, Escherichia coli P0298942.12, Escherichia coli P0298942.14, Escherichia coli P0298942.11, Escherichia coli P0298942.10, Escherichia coli 2864350, Escherichia coli 2862600, Escherichia coli P0298942.1, Escherichia coli MP020980.2, Escherichia coli 2780750, Escherichia coli 2845350, Escherichia coli O104:H4 str. E112/10, Escherichia coli O104:H4 str. E92/11, Escherichia coli KTE203, Escherichia coli KTE48, Escherichia coli KTE119, Escherichia coli KTE56, Escherichia coli KTE210, Escherichia coli O104:H4 str. Ec11-9941, Escherichia coli O104:H4 str. Ec12-0466, Escherichia coli O104:H4 str. Ec11-6006, Escherichia coli O104:H4 str. Ec12-0465, Escherichia coli O104:H4 str. Ec11-5604, Escherichia coli O104:H4 str. Ec11-5603, Escherichia coli O104:H4 str. Ec11-4988, Escherichia coli O104:H4 str. Ec11-4987, Escherichia coli O104:H4 str. Ec11-4986, Escherichia coli O104:H4 str. Ec11-4984, Escherichia coli O104:H4 str. Ec11-9450, Escherichia coli O104:H4 str. Ec11-9990, Escherichia coli O104:H4 str. 11-04080, Escherichia coli O104:H4 str. 11-03943, Escherichia coli O104:H4 str. 11-03439, Escherichia coli O104:H4 str. 11-02913, Escherichia coli O104:H4 str. 11-02318, Escherichia coli O104:H4 str. 11-02281, Escherichia coli O104:H4 str. 11-02093, Escherichia coli O104:H4 str. 11-02092, Escherichia coli O104:H4 str. 11-02033-1, Escherichia coli O104:H4 str. 11-02030, Escherichia coli O111:H8 str. CFSAN001632, Escherichia coli O26:H11 str. CFSAN001629, Escherichia coli O111:H11 str. CFSAN001630, Escherichia coli EC1865, Escherichia coli O104:H4 str. 2009EL-2071, Escherichia coli O104:H4 str. 2009EL-2050, Escherichia coli O26:H11 str. CVM9952, Escherichia coli O26:H11 str. CVM10030, Escherichia coli O111:H11 str. CVM9455, Escherichia coli O111:H11 str. CVM9553, Escherichia coli O26:H11 str. CVM10021, Escherichia coli O111:H8 str. CVM9602, Escherichia coli O26:H11 str. CVM10224, Escherichia coli O111:H8 str. CVM9634, Escherichia coli MT8, Escherichia coli O26:H11 str. CVM10026, Escherichia coli O26:H11 str. CVM9942, Escherichia coli O111:H11 str. CVM9545, Escherichia coli O111:H8 str. CVM9574, Escherichia coli O111:H8 str. CVM9570, Escherichia coli O111:H11 str. CVM9534, Escherichia coli 900105 (10e), Escherichia coli JB1-95, Escherichia coli 4.0522, Escherichia coli 99.0741, Escherichia coli DEC14A, Escherichia coli DEC10F, Escherichia coli DEC10C, Escherichia coli DEC10B, Escherichia coli DEC10D, Escherichia coli DEC10A, Escherichia coli DEC9E, Escherichia coli DEC9D, Escherichia coli DEC9C, Escherichia coli DEC8E, Escherichia coli DEC9B, Escherichia coli DEC9A, Escherichia coli DEC8D, Escherichia coli DEC8C, Escherichia coli DEC8B, Escherichia coli DEC8A, Escherichia coli O104:H4 str. 11-4632 C5, Escherichia coli O104:H4 str. 11-4632 C4, Escherichia coli O104:H4 str. 11-4632 C3, Escherichia coli O104:H4 str. 11-4632 C2, Escherichia coli O104:H4 str. 11-4632 C1, Escherichia coli O104:H4 str. 11-4623, Escherichia coli O104:H4 str. 11-4522, Escherichia coli O104:H4 str. 11-4404, Escherichia coli O104:H4 str. 11-3677, Escherichia coli O104:H4 str. 09-7901, Escherichia coli O104:H4 str. 04-8351, Escherichia coli O104:H4 str. C236-11, Escherichia coli 2534-86, Escherichia coli O104:H4 str. LB226692, Escherichia coli O104:H4 str. 01-09591, Escherichia coli E1520, Escherichia coli 1180, Escherichia coli EPECa14, Escherichia coli ATCC 8739, Escherichia coli O26:H11, Escherichia coli O111:H- str. 11128, Escherichia coli O26:H11 str. 11368, Escherichia coli 55989 Bacteria UP000036210, UP000006167, UP000004370, UP000031758, UP000028112, UP000027658, UP000027683, UP000028145, UP000027623, UP000027941, UP000028072, UP000027708, UP000027929, UP000027846, UP000027904, UP000027917, UP000028126, UP000027885, UP000027544, UP000023925, UP000023800, UP000024016, UP000024083, UP000023799, UP000024274, UP000024241, UP000024088, UP000023892, UP000023907, UP000023863, UP000024319, UP000024053, UP000024147, UP000023808, UP000023825, UP000023847, UP000024201, UP000023919, UP000024186, UP000024219, UP000024050, UP000023893, UP000023976, UP000024143, UP000023849, UP000023986, UP000023883, UP000024155, UP000023891, UP000024169, UP000024031, UP000024000, UP000032208, UP000024229, UP000024044, UP000023897, UP000024041, UP000023990, UP000024239, UP000024233, UP000024271, UP000024307, UP000024194, UP000024133, UP000023890, UP000023969, UP000024252, UP000024033, UP000023836, UP000023928, UP000024313, UP000023909, UP000023857, UP000024035, UP000024014, UP000023846, UP000024253, UP000024198, UP000023915, UP000024236, UP000024045, UP000024119, UP000024063, UP000023995, UP000024296, UP000024060, UP000024023, UP000023810, UP000023951, UP000024069, UP000023935, UP000024013, UP000018836, UP000018854, UP000018675, UP000017749, UP000017444, UP000017579, UP000016019, UP000016563, UP000016269, UP000016041, UP000016122, UP000016423, UP000016345, UP000012351, UP000012246, UP000012187, UP000012267, UP000012367, UP000012202, UP000012234, UP000012359, UP000012335, UP000012297, UP000012291, UP000012260, UP000012252, UP000012383, UP000012265, UP000012345, UP000012322, UP000012279, UP000012355, UP000012077, UP000012068, UP000010587, UP000010677, UP000010655, UP000010501, UP000010649, UP000010910, UP000010428, UP000010461, UP000010444, UP000010443, UP000010453, UP000010415, UP000010440, UP000010425, UP000010426, UP000010977, UP000010913, UP000010424, UP000010459, UP000010456, UP000010439, UP000010451, UP000010458, UP000010449, UP000010418, UP000010437, UP000010455, UP000011914, UP000012032, UP000011927, UP000007126, UP000006093, UP000006090, UP000009386, UP000006337, UP000006328, UP000006311, UP000006341, UP000006340, UP000002810, UP000006261, UP000004821, UP000005368, UP000004608, UP000005142, UP000005405, UP000003883, UP000003212, UP000005325, UP000003209, UP000004262, UP000018180, UP000003383, UP000003348, UP000005353, UP000005455, UP000003317, UP000005155, UP000004613, UP000003624, UP000003078, UP000004039, UP000003373, UP000003269, UP000004142, UP000004556, UP000004241, UP000005854, UP000003431, UP000005716, UP000003060, UP000005599, UP000004616, UP000004249, UP000004975, UP000005619, UP000005052, UP000005970, UP000005454, UP000004901, UP000003849, UP000003589, UP000004213, UP000004035, UP000005473, UP000004526, UP000000317, UP000001614, UP000001617, UP000000746 447199672, 407484276, 848545589, 848539935, 848535300, 848532315, 848526004, 848519171, 848504166, 848503467, 838747887, 823044890, 823044179, 823036738, 823034023, 823024467, 823017488, 823006171, 822950774, 822937873, 816212720, 788923567, 788907848, 765192898, 765181731, 765179157, 765177284, 765105647, 765100552, 751383013, 748105601, 748097924, 748086723, 732673823, 730004231, 724489475, 724487455, 699391455, 699383177, 660262137, 660001070, 652230970, 652108637, 651836589, 651701699, 651700265, 651698277, 651691583, 651685891, 651650578, 651345912, 650140347, 649991694, 636538282, 635836911, 612243073, 612240965, 612238863, 612233028, 612232998, 611114315, 611104724, 608766899, 608765505, 608757497, 608752171, 608748968, 608736140, 608732470, 608731770, 608726339, 608717057, 608712821, 608704250, 608702787, 608697003, 608691436, 608676237, 608675228, 608663407, 608662077, 608650974, 608650155, 607772582, 607760785, 607756640, 607738608, 607717064, 607710035, 607683366, 607672736, 607672164, 607666024, 607664822, 607658580, 607650893, 607647281, 607640545, 607632109, 607389798, 607011660, 606971317, 606949685, 606947075, 606939406, 606907728, 606864225, 606862111, 606860193, 606841889, 606839997, 606836113, 606828901, 606826267, 606775795, 606763892, 606748222, 606729740, 606728811, 606717708, 606670819, 606654365, 606645100, 606501067, 606432931, 606428682, 606423327, 606415241, 595597346, 595592746, 595586192, 566658585, 566116752, 564855455, 556152812, 553587973, 553339526, 536031127, 535924516, 535760818, 535748792, 535717995, 535644061, 535044362, 477081246, 477080532, 477067342, 477054293, 476882468, 476880948, 476879909, 476864660, 476863202, 476858773, 476855899, 476849266, 476836220, 476789036, 476787980, 476705466, 476327178, 476225922, 476207254, 472414893, 472412161, 431475120, 431314995, 431206959, 431111187, 431012138, 429458340, 429453966, 429447326, 429441930, 429437843, 429431536, 429426566, 429422493, 429414943, 429412495, 429404108, 429401315, 429399109, 429389836, 429387926, 429385981, 429373184, 429370577, 429369880, 429356157, 429355270, 429354365, 421945839, 421943594, 421934511, 408292819, 407063035, 407056573, 406779984, 394418926, 394417588, 394406036, 394401733, 394401192, 394384964, 394384926, 394384635, 388421081, 388372451, 388368703, 388356961, 388355907, 388350718, 388337634, 386259891, 386194795, 386186743, 386174284, 378211773, 378124078, 378120651, 378120412, 378113844, 378093233, 378088512, 378085916, 378078300, 378075259, 378072521, 378067533, 378057364, 378047518, 378045020, 378042029, 354919790, 354911909, 354909179, 354907404, 354903882, 354891850, 354888297, 354884519, 354875796, 354870030, 354861324, 354860800, 354857007, 345331576, 341921715, 340737581, 340732010, 323933964, 323177549, 323155558, 169756931, 745374512, 740525135, 665440900, 633874292, 257767061, 257756753, 254784163, 218354434, 189030274 KMM12839.1, KMM07972.1, KMM03910.1, KMM01082.1, KML95032.1, KML88699.1, KML74733.1, KML74105.1, KLX30952.1, KLH66183.1, KLH65487.1, KLH58361.1, KLH55846.1, KLH46562.1, KLH39988.1, KLH28998.1, KLG75371.1, KLG62821.1, AKE86526.1, KJW72503.1, KJW57800.1, KJD90916.1, KJD80048.1, KJD77515.1, KJD75671.1, KJD65275.1, KJD60393.1, AJF58840.1, KIH12126.1, KIH04789.1, KIG93861.1, AIZ80632.1, KHI93034.1, KHD48993.1, KHD47039.1, KGM70630.1, KGM62873.1, KEN52649.1, KEL00094.1, KDZ37739.1, KDY23089.1, KDX10862.1, KDV81659.1, KDV80942.1, KDV78265.1, KDV73693.1, KDV68031.1, KDV32939.1, KDV13753.1, KDU59873.1, KDT16830.1, KDM70028.1, KDG17995.1, EZQ37197.1, EZQ35183.1, EZQ33206.1, EZQ27527.1, EZQ27499.1, EZK14176.1, EZK05209.1, EZH53186.1, EZH51885.1, EZH44541.1, EZH39495.1, EZH36545.1, EZH24642.1, EZH21228.1, EZH20645.1, EZH15819.1, EZH06882.1, EZH03223.1, EZG94964.1, EZG93589.1, EZG88373.1, EZG83093.1, EZG69257.1, EZG68360.1, EZG57592.1, EZG56448.1, EZG46227.1, EZG45516.1, EZE53282.1, EZE41855.1, EZE37890.1, EZE20453.1, EZD99699.1, EZD92973.1, EZD67323.1, EZD57124.1, EZD56561.1, EZD50558.1, EZD49415.1, EZD43502.1, EZD36162.1, EZD32718.1, EZD26123.1, EZD18072.1, EZA82044.1, EZA40017.1, EZA01839.1, EYZ80973.1, EYZ78582.1, EYZ71549.1, EYZ41400.1, EYZ00038.1, EYY98007.1, EYY96155.1, EYY78928.1, EYY77106.1, EYY73447.1, EYY66859.1, EYY64323.1, EYY16658.1, EYY05341.1, EYX90653.1, EYX72976.1, EYX72104.1, EYX61958.1, EYX17517.1, EYX01892.1, EYW92889.1, EYV56769.1, EYU91373.1, EYU87339.1, EYU82461.1, EYU74619.1, AHM41241.1, AHM36642.1, AHM30534.1, ETJ60503.1, ETI75233.1, ETD64784.1, ESP40946.1, ESD09182.1, ESA67162.1, ERB30035.1, ERA54827.1, EQY94432.1, EQY82738.1, EQY52678.1, EQX80323.1, EQR91393.1, END62448.1, END61766.1, END49305.1, END37112.1, ENB74213.1, ENB72756.1, ENB71809.1, ENB57447.1, ENB56960.1, ENB53548.1, ENB50820.1, ENB44569.1, ENB35202.1, ENA90710.1, ENA89675.1, ENA10578.1, EMX44695.1, EMW45510.1, EMW27551.1, EMR97580.1, EMR94905.1, ELH54924.1, ELG02925.1, ELF05277.1, ELE15101.1, ELD26203.1, EKZ94167.1, EKZ89833.1, EKZ83249.1, EKZ77894.1, EKZ73840.1, EKZ67584.1, EKZ62654.1, EKZ58610.1, EKZ51116.1, EKZ48690.1, EKZ40387.1, EKZ37621.1, EKZ35432.1, EKZ26254.1, EKZ24355.1, EKZ22432.1, EKZ09732.1, EKZ07142.1, EKZ06451.1, EKY92838.1, EKY91962.1, EKY91065.1, EKU03024.1, EKU00876.1, EKT92275.1, EKJ11312.1, AFS84082.1, AFS76624.1, AFS59408.1, EJE92568.1, EJE91312.1, EJE81119.1, EJE77512.1, EJE77037.1, EJE62513.1, EJE62477.1, EJE62192.1, EIL80708.1, EIL35875.1, EIL32327.1, EIL21593.1, EIL20722.1, EIL16052.1, EIL04132.1, EIJ15365.1, EIH89038.1, EIH75566.1, EIH46284.1, EHX72107.1, EHW85491.1, EHW82121.1, EHW81889.1, EHW75404.1, EHW55050.1, EHW50364.1, EHW47798.1, EHW40289.1, EHW37286.1, EHW34579.1, EHW29652.1, EHW19597.1, EHW09881.1, EHW07427.1, EHW04483.1, EHF79730.1, EHF71912.1, EHF69213.1, EHF67467.1, EHF63981.1, EHF52069.1, EHF48557.1, EHF44831.1, EHF36161.1, EHF30436.1, EHF21764.1, EHF21241.1, EHF17464.1, EGW64036.1, EGT71311.1, EGR71836.1, EGR61149.1, EGB30438.1, EFZ63134.1, EFZ41735.1, ACA79630.1 WP_001276928.1, YP_006781426.1 B7LA88, B1IUQ3 THIC_ECO55, THIC_ECOLC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2464449, 5692520, 7683465, 5882527, 2453192, 3197278, 7646335 fig|1240766.3.peg.3204, fig|1005550.3.peg.5034, fig|868181.3.peg.21, fig|868170.3.peg.4686, fig|1048265.3.peg.3520, fig|1240761.3.peg.3179, fig|1068623.3.peg.4991, fig|1240758.3.peg.3183, fig|1165944.3.peg.4457, fig|1038844.15.peg.2715, fig|1240776.3.peg.2089, fig|1240774.3.peg.1922, fig|585396.4.peg.4992, fig|1068622.3.peg.3153, fig|1116025.3.peg.4660, fig|1240773.3.peg.3577, fig|869681.3.peg.4947, fig|1116139.3.peg.4882, fig|1240770.3.peg.1242, fig|1068621.3.peg.1211, fig|1116143.3.peg.4643, fig|1165943.3.peg.3840, fig|1165949.3.peg.4522, fig|1136217.3.peg.4456, fig|573235.3.peg.5258, fig|1125638.3.peg.5031, fig|1240767.3.peg.2476, fig|1125640.3.peg.4684, fig|1163391.3.peg.4004, fig|1068618.3.peg.1201, fig|1240777.3.peg.1834, fig|1068616.3.peg.3576, fig|1240764.3.peg.4491, fig|868171.3.peg.4130, fig|1048254.3.peg.3140, fig|1240775.3.peg.1501, fig|868175.3.peg.4919, fig|1165953.3.peg.3760, fig|868179.3.peg.5073, fig|1165946.3.peg.4114, fig|1240769.3.peg.2722, fig|1240762.3.peg.4036, fig|1232151.3.peg.5406, fig|1181749.3.peg.814, fig|868182.3.peg.20, fig|869682.3.peg.5394, fig|1163738.3.peg.5278, fig|1042804.3.peg.5131, fig|868176.3.peg.4846, fig|1165939.3.peg.4565, fig|1116147.3.peg.4744, fig|1038927.4.peg.2210, fig|481805.3.peg.4337, fig|1116015.3.peg.4309, fig|1048266.3.peg.4937, fig|1165950.3.peg.5268, fig|1040638.5.peg.4568, fig|1240772.3.peg.2796, fig|1165951.3.peg.4088, fig|1116144.3.peg.4234, fig|670904.3.peg.3516, fig|868174.3.peg.36, fig|1240779.3.peg.3277, fig|1116149.3.peg.4291, fig|1240778.3.peg.5037, fig|868177.3.peg.4673, fig|1068617.3.peg.1209, fig|1068620.3.peg.4483, fig|656374.3.peg.4785, fig|1165945.3.peg.4243, fig|1068614.3.peg.2825, fig|869678.4.peg.1325, fig|1125639.3.peg.4512, fig|1240765.3.peg.5099, fig|1134782.3.peg.4977, fig|1240760.3.peg.3442, fig|670893.4.peg.2474, fig|868173.3.peg.4952, fig|1042803.5.peg.4464, fig|1116145.3.peg.4557, fig|1182710.3.peg.4728, fig|1116150.3.peg.4702, fig|1048334.3.peg.5009, fig|1068624.3.peg.4994, fig|1165952.3.peg.4166, fig|752790.3.peg.939, fig|754079.3.peg.5188, fig|868172.3.peg.5547, fig|1181756.3.peg.31, fig|1116124.3.peg.4509, fig|1240768.3.peg.2759, fig|1068619.3.peg.2825, fig|869695.3.peg.3705, fig|1055539.3.peg.4369, fig|585055.6.peg.4504, fig|1136218.3.peg.4914, fig|868201.3.peg.4297, fig|868183.3.peg.4267, fig|1182663.3.peg.2050, fig|1133853.3.peg.5051, fig|1116141.3.peg.4580, fig|1116142.3.peg.4508, fig|1240771.3.peg.1473, fig|1182655.3.peg.437, fig|1116148.3.peg.4710, fig|1232154.3.peg.786, fig|1165947.3.peg.4344, fig|1240759.3.peg.2433, fig|1133852.3.peg.5001, fig|1232150.3.peg.1872, fig|1048256.3.peg.5020, fig|1116146.3.peg.4257, fig|1240763.3.peg.2867, fig|1068615.3.peg.2833, fig|6666666.5522.peg.4420, fig|868185.3.peg.5444, fig|1116024.3.peg.4576, fig|1125635.3.peg.4614, fig|868178.3.peg.4944, fig|868180.3.peg.5577, fig|1048765.4.peg.2265, fig|869672.3.peg.3972, fig|1165942.3.peg.3627 626 631 yes 437965 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1491, 1408283, 1408285, 1302421, 515621, 445336 Clostridium botulinum, Clostridium botulinum CDC_1436, Clostridium botulinum CDC_297, Clostridium botulinum A1 str. CFSAN002368, Clostridium botulinum Ba4 str. 657, Clostridium botulinum Bf Bacteria UP000030128, UP000031447, UP000031505, UP000015062, UP000002333, UP000004197 489454652, 751976125, 747122237, 745826283, 700270924, 526253260, 229261591, 182675134, 259517472 KIN83069.1, AJE12279.1, AJD27713.1, KGO12737.1, EPS46134.1, ACQ52624.1, EDT87095.1 WP_003359938.1 C3L2Y4 THIC_CLOB6 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7507345, 4719539, 4717189 fig|515621.3.peg.3358, fig|445336.4.peg.361 437 437 yes 437966 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 434924, 360117, 360116 Coxiella burnetii CbuK_Q154, Coxiella burnetii RSA 334, Coxiella burnetii 'MSU Goat Q177' Bacteria UP000002504, UP000003628, UP000004522 212012425, 165916790, 120575738, 226695519 ACJ19805.1, EDR35394.1, EAX32362.1 B6J5W3 THIC_COXB1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 4267801, 5611881 fig|434924.4.peg.541, fig|360116.4.peg.556, fig|360117.3.peg.1484 547 554 yes 437967 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1126, 482300, 1160284, 213618, 1160280, 449447 Microcystis aeruginosa, Microcystis aeruginosa SPC 777, Microcystis aeruginosa PCC 9808, Microcystis aeruginosa PCC 7941, Microcystis aeruginosa PCC 9432, Microcystis aeruginosa NIES-843 Bacteria UP000014617, UP000005291, UP000003274, UP000005806, UP000001510 488839470, 513474096, 389827402, 389766229, 389675260, 189030275, 166089454 EPF21595.1 WP_002751876.1 B0JSK4 THIC_MICAN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3771488 fig|213618.3.peg.2936, fig|449447.3.peg.3955, fig|1160280.3.peg.5100, fig|1160284.3.peg.485, fig|482300.6.peg.2861 457 460 yes 437968 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 305, 267608 Ralstonia solanacearum, Ralstonia solanacearum GMI1000 Bacteria UP000029286, UP000001436 499309305, 24638273, 17427121 WP_011000080.1 Q8Y368 THIC_RALSO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 168390 fig|267608.1.peg.113 629 631 yes 437969 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 588857, 573062, 399726 Thermoanaerobacter sp. X561, Thermoanaerobacter sp. X513, Thermoanaerobacter sp. X514 Bacteria UP000005299, UP000002731, UP000002155 496343625, 307582109, 300888848, 166853866, 238687623 ADN55508.1, EFK83995.1, ABY92275.1 WP_009052803.1 B0K5Z9 THIC_THEPX Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7172067 fig|573062.3.peg.2080, fig|588857.3.peg.1439, fig|399726.4.peg.951 431 432 yes 437970 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 411461 Dorea formicigenerans ATCC 27755 Bacteria UP000005359 166028428 EDR47185.1 fig|742765.5.peg.3, fig|411461.4.peg.1529 437 438 yes 437971 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 633, 502800 Yersinia pseudotuberculosis, Yersinia pseudotuberculosis YPIII Bacteria UP000047176, UP000031889 501260423, 755375844, 169749139 AJJ57418.1, ACA66657.1 WP_012303441.1 fig|502800.3.peg.343 651 681 yes 437972 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 271098, 458817 Shewanella halifaxensis, Shewanella halifaxensis HAW-EB4 Bacteria UP000001317 501233979, 167353852, 189030297 ABZ76465.1 WP_012276997.1 B0TRP7 THIC_SHEHH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3785813 fig|458817.3.peg.1889 652 662 yes 437973 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 214853, 445971 Anaerofustis stercorihominis, Anaerofustis stercorihominis DSM 17244 Bacteria UP000005178 494109327, 169257675 EDS71641.1 WP_007050111.1 fig|445971.6.peg.1255 434 435 yes 437974 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1502, 451757 Clostridium perfringens, Clostridium perfringens NCTC 8239 Bacteria UP000059070, UP000004727 489567347, 182380700 EDT78179.1 WP_003471843.1 fig|451757.5.peg.1691 436 436 yes 437975 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 35701, 498761 Heliobacterium modesticaldum, Heliobacterium modesticaldum Ice1 Bacteria UP000008550 501238713, 167591072 ABZ82820.1 WP_012281731.1 fig|498761.3.peg.164 434 436 yes 437976 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 29347, 658085, 411468 Clostridium scindens, Lachnospiraceae bacterium 5_1_57FAA, Clostridium scindens ATCC 35704 Bacteria UP000005617, UP000003459 490745812, 336009873, 167661292 EGN39862.1, EDS05422.1 WP_004608120.1 fig|658085.3.peg.58, fig|411468.9.peg.3156 434 434 yes 437977 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 455583 uncultured marine crenarchaeote HF4000_APKG3B16 Archaea 167043748 ABZ08440.1 B3T781 B3T781_9ARCH 442 442 yes 437978 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 261302, 398527 Burkholderia phytofirmans, Burkholderia phytofirmans PsJN Bacteria UP000001739 501402090, 187715841, 238689581 ACD17065.1 WP_012433656.1 B2SXY6 THIC_PARPJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7149741 fig|398527.4.peg.6609 642 643 yes 437979 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 355278 Leptospira biflexa serovar Patoc strain 'Patoc 1 (Ames)' Bacteria UP000001846 167776428 ABZ94729.1 fig|355278.4.peg.2325, fig|456481.4.peg.2313 513 515 yes 437980 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 103690 Nostoc sp. PCC 7120 Bacteria UP000002483 499304381, 21759454, 17130328 WP_010995156.1 Q8YY69 THIC_NOSS1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 163338 fig|103690.1.peg.1292 455 457 yes 437981 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 405441, 183190 Xylella fastidiosa M23, Xylella fastidiosa Temecula1 Bacteria UP000001698, UP000002516 182631614, 28056896 ACB92390.1, AAO28768.1 Q87CY6 THIC_XYLFT Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2155377, 5575534 fig|405441.5.peg.1198, fig|945689.3.peg.1607, fig|183190.1.peg.862, fig|788929.3.peg.2500, fig|183190.5.peg.1174 596 618 yes 437982 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 178306, 13773 Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum Archaea UP000002439 UP000002439 18311872, 499316701, 18159285, 29337106 AAL62721.1 NP_558539.1, WP_011007193.1 Q8ZZC0 THIC_PYRAE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 182222 fig|178306.1.peg.229 421 430 yes 437983 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1763, 459424, 216594, 1131442 Mycobacterium liflandii 128FXT, Mycobacterium marinum M, Mycobacterium marinum E11 Bacteria UP000011157, UP000001190, UP000027618 501361118, 442581658, 183174085, 641303835, 238690953 AGC60801.1, ACC39195.1 WP_012392684.1 B2HQM5 THIC_MYCMM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5930394 fig|41514.4.peg.633, fig|216594.6.peg.786 544 546 yes 437984 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 198094, 1392, 260799, 1449979, 1452727, 261591, 1392837, 1412844, 1412842, 1412843, 743835, 673518, 1213182, 1211117, 768494, 592021, 568206, 405536, 486622, 486620, 486623, 486621, 486619, 486624, 261594, 1439874 Bacillus anthracis str. Ames, Bacillus anthracis, Bacillus anthracis str. Sterne, Bacillus anthracis str. V770-NP-1R, Bacillus anthracis str. Turkey32, Bacillus anthracis str. Vollum, Bacillus anthracis str. SVA11, Bacillus anthracis 52-G, Bacillus anthracis 9080-G, Bacillus anthracis 8903-G, Bacillus anthracis str. A16, Bacillus anthracis str. A16R, Bacillus anthracis str. BF1, Bacillus anthracis str. UR-1, Bacillus anthracis str. H9401, Bacillus anthracis str. A0248, Bacillus anthracis str. CDC 684, Bacillus anthracis Tsiankovskii-I, Bacillus anthracis str. A0174, Bacillus anthracis str. A0465, Bacillus anthracis str. A0389, Bacillus anthracis str. A0442, Bacillus anthracis str. A0193, Bacillus anthracis str. A0488, Bacillus anthracis str. 'Ames Ancestor', Bacillus anthracis CZC5 Bacteria UP000000427, UP000034470, UP000031875, UP000031832, UP000031908, UP000028952, UP000019421, UP000019400, UP000019382, UP000019381, UP000018902, UP000018942, UP000006082, UP000002750, UP000005004, UP000002335, UP000007965, UP000005574, UP000005521, UP000004482, UP000003054, UP000003421, UP000004293, UP000004126, UP000019198 30265254, 446737208, 49188062, 816639777, 816635988, 753760328, 753738095, 753722620, 753542065, 753491924, 753473509, 753452483, 753433135, 753417728, 753400895, 753350652, 753341296, 753314429, 753305627, 753270935, 752329264, 751423951, 741051087, 728974769, 728972663, 728971085, 721886725, 721882684, 721877612, 721871424, 721870815, 721859950, 721856514, 721846675, 721845784, 721845329, 721829949, 721828546, 721814844, 721812524, 721812423, 721796034, 721794538, 721792809, 675842933, 675837425, 674824086, 674822925, 674000463, 673996675, 673989248, 673963817, 673612214, 664796463, 589084845, 582086835, 582079729, 582073787, 570721371, 570715512, 403392151, 401819320, 384388932, 229265070, 227005476, 190561186, 172081731, 170668112, 170127293, 167529303, 167511540, 164714309, 49181989, 47505925, 30259931, 821583954, 821577869, 821572042, 576738130, 254784153, 254784152, 47606146 KKM32529.1, KKM28774.1, AJI40198.1, AJH93327.1, AJH89597.1, AJH97217.1, AJH55846.1, AJH51784.1, AJH45162.1, AJH38516.1, AJH35849.1, AJH28461.1, AJG87049.1, AJG82806.1, AJG68996.1, AJG64879.1, AJG46114.1, AJG31856.1, AJF92737.1, AJA89365.1, KHG63873.1, KHG61842.1, KHG60273.1, KHA45540.1, KHA41643.1, KHA36645.1, KHA30562.1, KHA29977.1, KHA19277.1, KHA15922.1, KHA06284.1, KHA05431.1, KHA05000.1, KGZ89801.1, KGZ88449.1, KGZ74899.1, KGZ72656.1, KGZ72565.1, KGZ56885.1, KGZ55451.1, KGZ53783.1, AIM14605.1, AIM09098.1, KFL76635.1, KFL75480.1, AIK50797.1, AIK65058.1, AIK58758.1, AIK30951.1, KFJ78973.1, AIF59317.1, AHK41360.1, EVU02757.1, EVT95914.1, EVT90125.1, AHE92708.1, AHE86851.1, EJY89408.1, EJT18500.1, AFH86593.1, ACQ46707.1, ACP15219.1, EDV15159.1, EDT66801.1, EDT18862.1, EDS96169.1, EDR92055.1, EDR86923.1, EDR19829.1, AAT57365.1, AAT34601.1, AAP29117.1 NP_847631.1, WP_000814464.1, YP_031315.1 C3P178, C3LEJ7, Q81WY7 THIC_BACAA, THIC_BACAC, THIC_BACAN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 267905, 7689826, 637539, 626820, 5125900, 7617007, 6056976, 5119538, 5091795, 6037203, 4713914, 6086366, 642943 fig|405536.3.peg.3753, fig|280354.3.peg.4121, fig|1297868.3.peg.5337, fig|191218.6.peg.1468, fig|1081943.3.peg.2345, fig|486620.3.peg.3621, fig|568206.3.peg.5739, fig|261591.3.peg.4759, fig|198094.1.peg.5059, fig|261594.1.peg.5365, fig|486619.4.peg.3830, fig|486622.3.peg.3454, fig|1248431.3.peg.5057, fig|1211117.3.peg.4611, fig|1213182.3.peg.5328, fig|592021.13.peg.5731, fig|486624.3.peg.1939, fig|1297866.3.peg.5314, fig|205919.3.peg.4954, fig|280477.3.peg.415, fig|1297867.3.peg.5336, fig|1248436.3.peg.5318, fig|212045.4.peg.3602, fig|260799.1.peg.5024, fig|768494.3.peg.5297, fig|486623.3.peg.3818, fig|486621.3.peg.4061, fig|280355.3.peg.3498 586 586 yes 437985 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 208962, 502347, 1115511 Escherichia albertii, Escherichia albertii TW07627, Escherichia albertii NBRC 107761 Bacteria UP000066054, UP000003042, UP000029463 447199633, 170121023, 689833757 EDS89954.1 WP_001276889.1 fig|502347.3.peg.4623 622 627 yes 437986 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 471827, 477974 Candidatus Desulforudis audaxviator, Candidatus Desulforudis audaxviator MP104C Bacteria UP000008544 501260066, 169639003, 238688344 ACA60509.1 WP_012303084.1 B1I672 THIC_DESAP Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1367750 fig|477974.3.peg.1940 432 432 yes 437987 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 1268995, 1268982, 439855 Escherichia coli, Escherichia coli 908525, Escherichia coli 907672, Escherichia coli SMS-3-5 Bacteria UP000036210, UP000017454, UP000017402, UP000007011 447199648, 553643095, 553589582, 170517756, 226695851 ESD61843.1, ESD10718.1, ACB15934.1 WP_001276904.1 B1LNU6 THIC_ECOSM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7304652 fig|439855.10.peg.4560 626 631 yes 437988 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1491, 498214 Clostridium botulinum, Clostridium botulinum A3 str. Loch Maree Bacteria UP000030128, UP000000722 501305359, 169405876, 238688537 ACA54287.1 WP_012342413.1 B1KZJ7 THIC_CLOBM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5719014 fig|498214.7.peg.3221 437 437 yes 437989 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1492, 632245, 447214 Clostridium butyricum, Clostridium butyricum E4 str. BoNT E BL5262, Clostridium butyricum 5521 Bacteria UP000032253, UP000003081, UP000005591 489505240, 237655124, 182377000 EEP52682.1, EDT74570.1 WP_003410121.1 fig|447214.4.peg.2723, fig|632245.3.peg.3932 433 433 yes 437990 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 148447, 391038 Burkholderia phymatum, Burkholderia phymatum STM815 Bacteria UP000001192 501369346, 184192735, 238691315 ACC70700.1 WP_012400912.1 B2JJF7 THIC_PARP8 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7086417 fig|391038.7.peg.1618 642 643 yes 437991 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 32008, 396598 Burkholderia graminis C4D1M Bacteria UP000005045 492938787, 170139111 EDT07300.1 WP_006052443.1 fig|396598.3.peg.6014 642 643 yes 437992 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 620, 344609 Shigella boydii CDC 3083-94 Bacteria UP000001030 447199682, 187427170, 238691710 ACD06444.1 WP_001276938.1 B2TWI1 THIC_SHIB3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6953952 fig|344609.11.peg.4887 626 631 yes 437993 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 349741 Akkermansia muciniphila ATCC BAA-835 Bacteria UP000001031 187426378 ACD05657.1 fig|349741.3.peg.1956 607 607 yes 437994 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 128827, 665941, 556270, 445974 Coprobacillus sp. 3_3_56FAA, Coprobacillus sp. D7, Clostridium ramosum DSM 1402 Bacteria UP000004267, UP000010306, UP000005798 489629945, 365262837, 229383191, 167705340 EHM92709.1, EEO33282.1, EDS19919.1 WP_003534385.1 fig|556270.3.peg.2263, fig|445974.6.peg.12, fig|665941.3.peg.1140 435 435 yes 437995 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1129, 32049 Synechococcus sp. PCC 7002 Bacteria UP000001688 501263441, 169885122, 238689040 ACA98835.1 WP_012306459.1 B1XIG4 THIC_SYNP2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5418350 fig|32049.15.peg.1044 460 461 yes 437996 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28110, 484022 Francisella philomiragia, Francisella philomiragia subsp. philomiragia ATCC 25017 Bacteria UP000031835, UP000001320 501236628, 754256854, 754255483, 167596313 AJI49225.1, AJI47855.1, ABZ86311.1 WP_012279646.1 fig|484022.8.peg.94, fig|484022.4.peg.88 592 592 yes 437997 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 439847 Salmonella enterica, Salmonella enterica subsp. enterica serovar Saintpaul str. SARA29 Bacteria UP000054489, UP000004363 486161743, 205321831 EDZ09670.1 WP_001525340.1 626 631 yes 437998 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 43988, 43989 Cyanothece sp. ATCC 51142 Bacteria UP000001203 497233407, 171699392, 226726954 ACB52373.1 WP_009547669.1 B1WW40 THIC_CYAA5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5429698 fig|43989.3.peg.2796, fig|860575.3.peg.4860 459 459 yes 437999 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 152480, 396597 Burkholderia ambifaria, Burkholderia ambifaria MEX-5 Bacteria UP000004814 493811548, 171095911 EDT40849.1 WP_006759244.1 fig|396597.3.peg.3372 642 643 yes 438000 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 509170 Acinetobacter baumannii SDF Bacteria UP000001741 238688135, 169153414 B0VMD7 THIC_ACIBS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3811262 fig|509170.6.peg.3100 621 625 yes 438001 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 498761 Heliobacterium modesticaldum Ice1 Bacteria UP000008550 167592883 ABZ84631.1 fig|498761.3.peg.1862 435 436 yes 438002 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 126740 Thermotoga sp. RQ2 Bacteria UP000001687 501267327, 170175448, 238688760 ACB08500.1 WP_012310345.1 B1LCP2 THIC_THESQ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7270731 fig|126740.4.peg.139 424 424 yes 438003 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 938141, 465518, 936157 Salmonella enterica, Salmonella enterica subsp. enterica serovar Sloterdijk str. ATCC 15791, Salmonella enterica subsp. enterica serovar Weltevreden str. HI_N05-537, Salmonella enterica subsp. enterica serovar Weltevreden str. 2007-60-3289-1 Bacteria UP000054489, UP000017437, UP000005684, UP000006374 446030553, 554100127, 205340591, 320088594 ESF41791.1, EDZ27355.1 WP_000108408.1 fig|465518.5.peg.4674, fig|936157.3.peg.4358 626 631 yes 438004 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1491, 445335 Clostridium botulinum, Clostridium botulinum NCTC 2916 Bacteria UP000030128, UP000002986 489452572, 182669658 EDT81634.1 WP_003357894.1 fig|445335.4.peg.1882 437 437 yes 438005 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1491, 498213 Clostridium botulinum, Clostridium botulinum B1 str. Okra Bacteria UP000030128, UP000008541 506438095, 169121366, 229558531 ACA45202.1 WP_015957812.1 B1ILH9 THIC_CLOBK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5714932 fig|498213.7.peg.3029 437 437 yes 438006 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1343737, 405440, 155919 Xylella fastidiosa subsp. multiplex Griffin-1, Xylella fastidiosa M12, Xylella fastidiosa Dixon Bacteria UP000016508, UP000008539, UP000004103 542423410, 167965026, 71163365 ERI59604.1, ACA12036.1, EAO13083.1 fig|155919.4.peg.1670, fig|405440.5.peg.1273, fig|405440.3.peg.982 597 618 yes 438007 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1260, 334413 Finegoldia magna, Finegoldia magna ATCC 29328 Bacteria UP000001319 501248065, 238687763, 167831930 WP_012291083.1 B0S3A6 THIC_FINM2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5506027 fig|334413.6.peg.1647 433 433 yes 438008 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 303, 76869 Pseudomonas putida, Pseudomonas putida GB-1 Bacteria UP000054813, UP000002157 501231468, 166862452, 189030279 ABZ00860.1 WP_012274486.1 B0KL24 THIC_PSEPG Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7017761 fig|76869.3.peg.4943 625 626 yes 438009 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1502, 451756 Clostridium perfringens, Clostridium perfringens CPE str. F4969 Bacteria UP000059070, UP000003224 489563931, 170714641 EDT26823.1 WP_003468451.1 fig|451756.6.peg.1661 436 436 yes 438010 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 407, 31998, 426355 Methylobacterium radiotolerans, Methylobacterium radiotolerans JCM 2831 Bacteria UP000032265, UP000006589 501277113, 758507661, 170656112 KIU32288.1, ACB25167.1 WP_012320131.1 fig|426355.14.peg.3257 622 628 yes 438011 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1502, 451755 Clostridium perfringens, Clostridium perfringens E str. JGS1987 Bacteria UP000059070, UP000005337 489557055, 170663843 EDT16526.1 WP_003461610.1 fig|451755.5.peg.395 436 436 yes 438012 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 611, 1182166, 1182169, 1182165, 1173848, 1173849, 1173846, 1173847, 1173845, 1173844, 1173843, 1173840, 1173841, 1173842, 1173839, 1173836, 1173838, 1173835, 1173837, 1054962, 1173834, 1054964, 1054956, 1054961, 1054955, 1054951, 1054954, 1054949, 1037261, 1037257, 1037259, 1037258, 1030007, 1054948, 925125, 1030004, 1030002, 1030000, 1124949, 59201, 1030003, 1037256, 1030001, 1054953, 1054952, 1128969, 1128967, 1128968, 1124946, 1124947, 1124948, 1124944, 1124945, 1124943, 1128965, 1128964, 1128962, 1128961, 1128960, 1128958, 1124940, 1128957, 1054965, 1124939, 1128956, 1124938, 1128955, 1054966, 1054957, 1054963, 1054960, 1054950, 1030005, 1030006, 1029996, 1029999, 1029998, 1128966, 1054958, 1054959, 1299044, 1124934, 1029997, 1124935, 1271864, 1124936, 1182170, 1182164, 1182167, 1182168, 1160717, 1128963, 1124942, 1124941, 1124937, 1128959, 454164, 454169 Salmonella enterica, Salmonella enterica subsp. enterica serovar Heidelberg, Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN00324, Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN00327, Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN00323, Salmonella enterica subsp. enterica serovar Heidelberg str. 92-0138, Salmonella enterica subsp. enterica serovar Heidelberg str. 92-0144, Salmonella enterica subsp. enterica serovar Heidelberg str. 89-0213, Salmonella enterica subsp. enterica serovar Heidelberg str. 90-0318, Salmonella enterica subsp. enterica serovar Heidelberg str. 88-0312, Salmonella enterica subsp. enterica serovar Heidelberg str. 87-0208, Salmonella enterica subsp. enterica serovar Heidelberg str. 86-0255, Salmonella enterica subsp. enterica serovar Heidelberg str. 83-1068, Salmonella enterica subsp. enterica serovar Heidelberg str. 84-1004, Salmonella enterica subsp. enterica serovar Heidelberg str. 85-0486, Salmonella enterica subsp. enterica serovar Heidelberg str. 82-1617, Salmonella enterica subsp. enterica serovar Heidelberg str. 77-1831, Salmonella enterica subsp. enterica serovar Heidelberg str. 79-0480, Salmonella enterica subsp. enterica serovar Heidelberg str. 76-0300, Salmonella enterica subsp. enterica serovar Heidelberg str. 77-2823, Salmonella enterica subsp. enterica serovar Heidelberg str. 579083-10, Salmonella enterica subsp. enterica serovar Heidelberg str. 75-3547, Salmonella enterica subsp. enterica serovar Heidelberg str. 670102-3, Salmonella enterica subsp. enterica serovar Heidelberg str. 622737-14, Salmonella enterica subsp. enterica serovar Heidelberg str. 622737-21, Salmonella enterica subsp. enterica serovar Heidelberg str. 622737-12, Salmonella enterica subsp. enterica serovar Heidelberg str. RI-11-013343, Salmonella enterica subsp. enterica serovar Heidelberg str. RI-11-014588, Salmonella enterica subsp. enterica serovar Heidelberg str. 579083-19, Salmonella enterica subsp. enterica serovar Heidelberg str. 579082-8, Salmonella enterica subsp. enterica serovar Heidelberg str. RI-11-013374, Salmonella enterica subsp. enterica serovar Heidelberg str. 622737-11, Salmonella enterica subsp. enterica serovar Heidelberg str. 607310-1, Salmonella enterica subsp. enterica serovar Heidelberg str. 670102-5, Salmonella enterica subsp. enterica serovar Heidelberg str. 632675-24, Salmonella enterica subsp. enterica serovar Heidelberg str. SARA36, Salmonella enterica subsp. enterica serovar Heidelberg str. 607309-34, Salmonella enterica subsp. enterica serovar Heidelberg str. 607309-5, Salmonella enterica subsp. enterica serovar Heidelberg str. RI-11-013193, Salmonella enterica subsp. enterica serovar Heidelberg str. SARA40, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Heidelberg str. 640151-11, Salmonella enterica subsp. enterica serovar Heidelberg str. RI-11-013312, Salmonella enterica subsp. enterica serovar Heidelberg str. RI-11-014319, Salmonella enterica subsp. enterica serovar Heidelberg str. RI-11-014316, Salmonella enterica subsp. enterica serovar Heidelberg str. RI-11-013988, Salmonella enterica subsp. enterica serovar Heidelberg str. N18453, Salmonella enterica subsp. enterica serovar Heidelberg str. N18413, Salmonella enterica subsp. enterica serovar Heidelberg str. N18440, Salmonella enterica subsp. enterica serovar Heidelberg str. CVM24359, Salmonella enterica subsp. enterica serovar Heidelberg str. CVM24388, Salmonella enterica subsp. enterica serovar Heidelberg str. CVM20752, Salmonella enterica subsp. enterica serovar Heidelberg str. N20134, Salmonella enterica subsp. enterica serovar Heidelberg str. CVM24391, Salmonella enterica subsp. enterica serovar Heidelberg str. 24393, Salmonella enterica subsp. enterica serovar Heidelberg str. 32507, Salmonella enterica subsp. enterica serovar Heidelberg str. N30678, Salmonella enterica subsp. enterica serovar Heidelberg str. N29341, Salmonella enterica subsp. enterica serovar Heidelberg str. 41584, Salmonella enterica subsp. enterica serovar Heidelberg str. 41576, Salmonella enterica subsp. enterica serovar Heidelberg str. 41567, Salmonella enterica subsp. enterica serovar Heidelberg str. N18393, Salmonella enterica subsp. enterica serovar Heidelberg str. N15757, Salmonella enterica subsp. enterica serovar Heidelberg str. N4541, Salmonella enterica subsp. enterica serovar Heidelberg str. N26457, Salmonella enterica subsp. enterica serovar Heidelberg str. N4630, Salmonella enterica subsp. enterica serovar Heidelberg str. N19871, Salmonella enterica subsp. enterica serovar Heidelberg str. 21381, Salmonella enterica subsp. enterica serovar Heidelberg str. N653, Salmonella enterica subsp. enterica serovar Heidelberg str. N189, Salmonella enterica subsp. enterica serovar Heidelberg str. N4403, Salmonella enterica subsp. enterica serovar Heidelberg str. N4496, Salmonella enterica subsp. enterica serovar Heidelberg str. SARA 39, Salmonella enterica subsp. enterica serovar Heidelberg str. N418, Salmonella enterica subsp. enterica serovar Heidelberg str. N19992, Salmonella enterica subsp. enterica serovar Heidelberg str. SARA37, Salmonella enterica subsp. enterica serovar Heidelberg str. SARA31, Salmonella enterica subsp. enterica serovar Heidelberg str. SARA32, Salmonella enterica subsp. enterica serovar Heidelberg str. 29169, Salmonella enterica subsp. enterica serovar Heidelberg str. N1514, Salmonella enterica subsp. enterica serovar Heidelberg str. N1536, Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN002064, Salmonella enterica subsp. enterica serovar Heidelberg str. 82-2052, Salmonella enterica subsp. enterica serovar Heidelberg str. SARA35, Salmonella enterica subsp. enterica serovar Heidelberg str. 24390, Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN002069, Salmonella enterica subsp. enterica serovar Heidelberg str. 41578, Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN00328, Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN00322, Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN00325, Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN00326, Salmonella enterica subsp. enterica serovar Heidelberg str. B182, Salmonella enterica subsp. enterica serovar Heidelberg str. 41565, Salmonella enterica subsp. enterica serovar Heidelberg str. 41566, Salmonella enterica subsp. enterica serovar Heidelberg str. 41563, Salmonella enterica subsp. enterica serovar Heidelberg str. 41579, Salmonella enterica subsp. enterica serovar Heidelberg str. 41573, Salmonella enterica subsp. enterica serovar Heidelberg str. SL486, Salmonella enterica subsp. enterica serovar Heidelberg str. SL476 Bacteria UP000054489, UP000054505, UP000033398, UP000033643, UP000033696, UP000033596, UP000033576, UP000032663, UP000033714, UP000033479, UP000033543, UP000033574, UP000032674, UP000033485, UP000033506, UP000033554, UP000033508, UP000032664, UP000033687, UP000033463, UP000033345, UP000033631, UP000033553, UP000033528, UP000033727, UP000033729, UP000032660, UP000033720, UP000032672, UP000033753, UP000033545, UP000033471, UP000033630, UP000033751, UP000032661, UP000032678, UP000033529, UP000033472, UP000033467, UP000033768, UP000033855, UP000027199, UP000027066, UP000027287, UP000027268, UP000027354, UP000019645, UP000019676, UP000019691, UP000019696, UP000019685, UP000019695, UP000019689, UP000019643, UP000019670, UP000019650, UP000019671, UP000019663, UP000019646, UP000019686, UP000019655, UP000019651, UP000019683, UP000019657, UP000019684, UP000019664, UP000019667, UP000019690, UP000019640, UP000019665, UP000019648, UP000019672, UP000019673, UP000019641, UP000019674, UP000019692, UP000019693, UP000019687, UP000019642, UP000019660, UP000019669, UP000018707, UP000017292, UP000017392, UP000017479, UP000014920, UP000014928, UP000006342, UP000006326, UP000006338, UP000006335, UP000007393, UP000005693, UP000004969, UP000004574, UP000003267, UP000002951, UP000003916, UP000001866 446030559, 808308177, 808288277, 808278405, 808257336, 781365517, 781364828, 781354800, 781352978, 781345317, 781337031, 781335612, 781333859, 781327960, 781326760, 781318643, 781317431, 781317229, 781300540, 781297106, 781295275, 781291982, 781290062, 781282501, 781276602, 781269315, 781263777, 781257387, 781254065, 781253717, 781247499, 781241603, 781231488, 781228942, 781223606, 781219537, 781213900, 781205494, 781204700, 781198754, 781193496, 781184025, 781182206, 738572218, 735732400, 735722735, 735710150, 735709336, 650153388, 650152081, 649500190, 649494380, 649487361, 599992144, 599987483, 599982849, 599973740, 599964579, 599963609, 599958967, 599952149, 599947610, 599941394, 599937720, 599937676, 599928451, 599918857, 599918442, 599916028, 599909860, 599906948, 599900869, 599898309, 599894008, 599883413, 599875802, 599866927, 599863912, 599860558, 599852786, 599851226, 599850437, 599838903, 599836118, 599836026, 598918066, 598910753, 598910334, 564746100, 553979221, 553975090, 553971474, 523803884, 523796844, 402532375, 402529181, 402527105, 402518539, 383796538, 381307963, 381307236, 381295187, 381294831, 381293336, 205336119, 194407883, 238690610 KKE52573.1, KKE33156.1, KKE23648.1, KKE02980.1, KJU68204.1, KJU67527.1, KJU57765.1, KJU56022.1, KJU48625.1, KJU40556.1, KJU39164.1, KJU37452.1, KJU31685.1, KJU30515.1, KJU22596.1, KJU21424.1, KJU21230.1, KJU05024.1, KJU01749.1, KJT99989.1, KJT96857.1, KJT95010.1, KJT87927.1, KJT82498.1, KJT75796.1, KJT70741.1, KJT64831.1, KJT61807.1, KJT61508.1, KJT56027.1, KJT50863.1, KJT42000.1, KJT39702.1, KJT34910.1, KJT31236.1, KJT26189.1, KJT18394.1, KJT17632.1, KJT11998.1, KJT06991.1, KJS98033.1, KJS96316.1, KHQ75619.1, KHP02914.1, KHO93330.1, KHO80841.1, KHO80056.1, KDU72660.1, KDU71399.1, KDS08590.1, KDS03173.1, KDR97828.1, EYI99940.1, EYI95660.1, EYI91259.1, EYI82657.1, EYI73913.1, EYI73030.1, EYI68589.1, EYI61995.1, EYI57633.1, EYI51632.1, EYI48057.1, EYI48016.1, EYI39211.1, EYI30079.1, EYI29681.1, EYI27389.1, EYI21508.1, EYI18719.1, EYI12915.1, EYI10469.1, EYI06330.1, EYH96311.1, EYH89589.1, EYH81772.1, EYH79050.1, EYH75953.1, EYH68487.1, EYH66968.1, EYH66200.1, EYH54987.1, EYH52260.1, EYH52197.1, EYE83688.1, EYE76690.1, EYE76282.1, AHB95949.1, ESE53542.1, ESE49522.1, ESE46067.1, AGQ77998.1, AGQ63001.1, EJW39571.1, EJW36422.1, EJW34369.1, EJW25917.1, AFH43620.1, EIC48809.1, EIC48098.1, EIC36306.1, EIC35959.1, EIC34506.1, EDZ22883.1, ACF68102.1 WP_000108414.1 B4TCT3 THIC_SALHS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7365400, 4797308 fig|1124941.3.peg.3407, fig|1182167.3.peg.518, fig|1128963.3.peg.3612, fig|1160717.4.peg.260, fig|1182170.3.peg.837, fig|1124942.3.peg.3451, fig|1128959.3.peg.4307, fig|454169.6.peg.4416, fig|1182164.3.peg.342, fig|1124937.3.peg.2931, fig|1182168.3.peg.3409, fig|454164.6.peg.4520 626 631 yes 438013 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 149385, 1182171, 1194152, 930771, 1124933, 1079477, 930770, 465516, 1327958 Salmonella enterica, Salmonella enterica subsp. enterica serovar Hadar, Salmonella enterica subsp. enterica serovar Braenderup str. CFSAN000756, Salmonella enterica subsp. enterica serovar Manhattan str. CFSAN001078, Salmonella enterica subsp. enterica serovar Braenderup str. ATCC BAA-664, Salmonella enterica subsp. enterica serovar Hadar str. ATCC 51956, Salmonella enterica subsp. enterica serovar Muenchen str. baa1594, Salmonella enterica subsp. enterica serovar Muenchen str. ATCC 8388, Salmonella enterica subsp. enterica serovar Hadar str. RI_05P066, Salmonella enterica subsp. enterica serovar Manhattan str. 111113 Bacteria UP000054489, UP000054540, UP000017366, UP000017410, UP000017465, UP000017376, UP000017346, UP000017409, UP000003471, UP000035820 446030568, 808255308, 808247789, 808235112, 554468996, 554446901, 554300351, 554270092, 554223303, 554059252, 205346987, 702157052 KKE00994.1, KKD93615.1, KKD81137.1, ESJ86850.1, ESJ68660.1, ESH36541.1, ESH06115.1, ESG60938.1, ESF03707.1, EDZ33618.1 WP_000108423.1 fig|1328333.3.peg.1676, fig|465516.5.peg.4537, fig|1212559.4.peg.4523, fig|1328334.3.peg.461, fig|1328328.3.peg.2396 626 631 yes 438014 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 167965, 471821 uncultured Termite group 1 bacterium, uncultured Termite group 1 bacterium phylotype Rs-D17 Environmental samples UP000001691 505236622, 189485723, 170287682 WP_015423724.1, YP_001956664.1 fig|471821.5.peg.1233 421 421 yes 438015 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 588, 1157951, 471874 Providencia stuartii, Providencia stuartii MRSN 2154, Providencia stuartii ATCC 25827 Bacteria UP000030405, UP000005012, UP000004506 491063163, 721478831, 684201059, 384479779, 188023215 KGY22417.1, AIN63286.1, AFH93574.1, EDU61255.1 WP_004924795.1 fig|471874.6.peg.3395, fig|1157951.4.peg.1706 623 649 yes 438016 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 366602 Caulobacter sp. K31 Bacteria UP000001316 501244183, 167349567, 189030271 ABZ72302.1 WP_012287201.1 B0T2Q1 THIC_CAUSK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7043650 fig|366602.3.peg.3541 607 611 yes 438017 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1911, 455632 Streptomyces griseus, Streptomyces griseus subsp. griseus NBRC 13350 Bacteria UP000032367, UP000001685 501348425, 238688984, 178465962 WP_012380060.1 B1VPA3 THIC_STRGG Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5656238 fig|455632.3.peg.3724 583 606 yes 438018 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 34029, 395495 Leptothrix cholodnii, Leptothrix cholodnii SP-6 Bacteria UP000001693 501315816, 170776556, 238689114 ACB34695.1 WP_012347451.1 B1Y5I3 THIC_LEPCP Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5550697 fig|395495.3.peg.2326, fig|395495.5.peg.2448 623 628 yes 438019 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 105841, 411490 Anaerostipes caccae, Anaerostipes caccae DSM 14662 Bacteria UP000004935 493613882, 167654476 EDR98605.1 WP_006566163.1 fig|411490.6.peg.720 433 433 yes 438020 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 261299, 445973 Clostridium bartlettii, Clostridium bartlettii DSM 16795 Bacteria UP000003364 494498077, 164602282 EDQ95747.1 WP_007287543.1 fig|445973.7.peg.2318 434 434 yes 438021 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 192955, 1029980, 1156551, 1124954, 1124953, 1124950, 1124952, 1124951, 866919, 454231, 439842 Salmonella enterica, Salmonella enterica subsp. enterica serovar Kentucky, Salmonella enterica subsp. enterica serovar Kentucky str. 5349, Salmonella enterica subsp. enterica serovar Kentucky str. 0253, Salmonella enterica subsp. enterica serovar Kentucky str. 20793, Salmonella enterica subsp. enterica serovar Kentucky str. N312, Salmonella enterica subsp. enterica serovar Kentucky str. 13562, Salmonella enterica subsp. enterica serovar Kentucky str. 22694, Salmonella enterica subsp. enterica serovar Kentucky str. 29166, Salmonella enterica subsp. enterica serovar Kentucky str. 29439, Salmonella enterica subsp. enterica serovar Kentucky str. CDC 191, Salmonella enterica subsp. enterica serovar Kentucky str. CVM29188 Bacteria UP000054489, UP000066356, UP000017414, UP000017533, UP000017104, UP000017099, UP000017144, UP000017086, UP000017111, UP000018140, UP000004321, UP000005051 446030554, 808335936, 808297722, 808262200, 808245968, 554241035, 553483696, 549576177, 549569646, 549561431, 549560815, 549559056, 444820220, 205331659, 194457240 KKE75452.1, KKE42302.1, KKE07716.1, KKD91848.1, ESG77960.1, ESC07764.1, ERN80983.1, ERN74647.1, ERN66737.1, ERN66138.1, ERN64432.1, ELX47664.1, EDZ18423.1, EDX46079.1 WP_000108409.1 fig|439842.10.peg.3936, fig|454231.5.peg.4539 626 631 yes 438022 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 909768, 1409924, 1409922, 1409923, 1409926, 1409928, 1409925, 1409927, 470, 1116234, 1370126, 575584, 1439316, 1310903, 1311128, 1310830, 1310829, 1310827, 1310697, 1310736, 1310700, 1310661, 1310656, 1310809, 1310575, 1224747, 1198108, 1455316, 1310797, 1311099, 1311100, 1311101, 1311103, 1311105, 1311106, 1311107, 1310902, 1310904, 1310897, 1310898, 1310899, 1310900, 1310901, 1310787, 1310803, 1310789, 1310786, 1310801, 1310762, 1310795, 1310802, 1310784, 1310748, 1310722, 1310705, 1310710, 1310707, 1310729, 1310738, 1310706, 1310752, 1310730, 1310728, 1310725, 1310818, 1310820, 1310807, 1310812, 1310702, 1310688, 1310679, 1310675, 1310674, 1310663, 1310662, 1310659, 1310655, 1310657, 1310654, 1310579, 1310577, 1310580, 1310597, 1310583, 1310570, 1310554, 1310630, 1310637, 1310634, 1310607, 1310645, 1310619, 1310615, 1310613, 1310628, 1310618, 1310622, 1310606, 1413216, 1398965, 1398970, 1343075, 1398991, 1398988, 1398949, 1398989, 1398990, 1398987, 1398985, 1398984, 1398986, 1398983, 1398982, 1398981, 1398980, 1398978, 1398976, 1398977, 1398975, 1398974, 1398973, 1398972, 1398969, 1398967, 1398968, 1398966, 1398962, 1398964, 1398963, 1398960, 1398961, 1398959, 1398956, 1398957, 1398958, 1398954, 1398955, 1398951, 1398953, 1398952, 1398947, 1398950, 1398948, 1398946, 1398945, 1398943, 1398944, 1400867, 1358412, 1351817, 1096997, 1096995, 1217638, 1217631, 1217628, 1217636, 1217637, 1217627, 1217632, 1217635, 1217630, 1217673, 1217985, 1217647, 1217640, 1217644, 1217645, 1217641, 1217642, 1217643, 1217646, 1094488, 1094484, 1094487, 1094486, 1094481, 1094483, 1094480, 1094479, 1094478, 1094477, 1094471, 1094475, 1094474, 1094470, 1224166, 945556, 1278070, 903927, 903934, 903933, 903937, 903931, 903920, 903919, 903917, 903926, 903925, 903924, 903923, 903935, 903932, 903909, 903903, 903904, 903901, 903906, 903905, 903907, 903908, 1100841, 1224141, 1223564, 1168588, 1168590, 903914, 903912, 903911, 903898, 903899, 903895, 903896, 903892, 903894, 903889, 889738, 992404, 992403, 886886, 525242, 592014, 525243, 696749, 557600, 480119, 400667, 405416, 509173 Acinetobacter baumannii MRSN 3942, Acinetobacter baumannii MRSN 3405, Acinetobacter baumannii MRSN 3527, Acinetobacter baumannii MRSN 58, Acinetobacter baumannii MRSN 7341, Acinetobacter baumannii MRSN 4106, Acinetobacter baumannii MRSN 7339, Acinetobacter baumannii, Acinetobacter baumannii AB5075, Acinetobacter baumannii DU202, Acinetobacter baumannii ATCC 19606, Acinetobacter baumanii BIDMC 56, Acinetobacter baumannii 45002_9, Acinetobacter baumannii 45057_1, Acinetobacter baumannii 929679-598, Acinetobacter baumannii 1276470-132, Acinetobacter baumannii 1262761-105, Acinetobacter baumannii 21072, Acinetobacter baumannii 233846, Acinetobacter baumannii 1598530, Acinetobacter baumannii 855125, Acinetobacter baumannii 1146103, Acinetobacter baumannii 1539026, Acinetobacter baumannii 6935, Acinetobacter baumannii AC30, Acinetobacter baumannii AC12, Acinetobacter baumannii R1B, Acinetobacter baumannii 1428368, Acinetobacter baumannii 16553_2, Acinetobacter baumannii 16553_3, Acinetobacter baumannii 16553_4, Acinetobacter baumannii 16553_6, Acinetobacter baumannii 16553_8, Acinetobacter baumannii 16553_9, Acinetobacter baumannii 16553_10, Acinetobacter baumannii 45002_8, Acinetobacter baumannii 45002_10, Acinetobacter baumannii 45002_3, Acinetobacter baumannii 45002_4, Acinetobacter baumannii 45002_5, Acinetobacter baumannii 45002_6, Acinetobacter baumannii 45002_7, Acinetobacter baumannii 70136, Acinetobacter baumannii 730795, Acinetobacter baumannii 145660, Acinetobacter baumannii 541915, Acinetobacter baumannii 339786, Acinetobacter baumannii 1391434, Acinetobacter baumannii 1281984, Acinetobacter baumannii 11126, Acinetobacter baumannii 1007214, Acinetobacter baumannii 846928, Acinetobacter baumannii 825610, Acinetobacter baumannii 694762, Acinetobacter baumannii 3390, Acinetobacter baumannii 318814, Acinetobacter baumannii 23671, Acinetobacter baumannii 273929, Acinetobacter baumannii 1412924, Acinetobacter baumannii 1293320, Acinetobacter baumannii 1207552, Acinetobacter baumannii 1245593, Acinetobacter baumannii 1062314, Acinetobacter baumannii 121738, Acinetobacter baumannii 323408, Acinetobacter baumannii 1488685, Acinetobacter baumannii 1552389, Acinetobacter baumannii 831240, Acinetobacter baumannii 144107, Acinetobacter baumannii 1552865, Acinetobacter baumannii 1526966, Acinetobacter baumannii 1546444, Acinetobacter baumannii 1440750, Acinetobacter baumannii 50595, Acinetobacter baumannii 1106579, Acinetobacter baumannii 1277411, Acinetobacter baumannii 1096934, Acinetobacter baumannii 1291820, Acinetobacter baumannii 58452, Acinetobacter baumannii 532413, Acinetobacter baumannii 1297, Acinetobacter baumannii 1247182, Acinetobacter baumannii 1051176, Acinetobacter baumannii 1046051, Acinetobacter baumannii 1036938, Acinetobacter baumannii 99063, Acinetobacter baumannii 809848, Acinetobacter baumannii 4749, Acinetobacter baumannii 625974, Acinetobacter baumannii 1461963, Acinetobacter baumannii 1419130, Acinetobacter baumannii 1396970, Acinetobacter baumannii 1295743, Acinetobacter baumannii 1267820, Acinetobacter baumannii 118362, Acinetobacter baumannii 1035119, Acinetobacter baumannii 1297549, Acinetobacter baumannii AB07, Acinetobacter baumannii UH2107, Acinetobacter baumannii UH3807, Acinetobacter baumannii CI77, Acinetobacter baumannii UH9907, Acinetobacter baumannii UH8907, Acinetobacter baumannii UH10707, Acinetobacter baumannii UH9007, Acinetobacter baumannii UH9707, Acinetobacter baumannii UH8807, Acinetobacter baumannii UH8407, Acinetobacter baumannii UH8107, Acinetobacter baumannii UH8707, Acinetobacter baumannii UH7907, Acinetobacter baumannii UH7807, Acinetobacter baumannii UH7707, Acinetobacter baumannii UH7607, Acinetobacter baumannii UH6907, Acinetobacter baumannii UH6207, Acinetobacter baumannii UH6507, Acinetobacter baumannii UH6107, Acinetobacter baumannii UH5707, Acinetobacter baumannii UH5307, Acinetobacter baumannii UH5207, Acinetobacter baumannii UH2907, Acinetobacter baumannii UH2307, Acinetobacter baumannii UH2707, Acinetobacter baumannii UH22908, Acinetobacter baumannii UH19608, Acinetobacter baumannii UH20108, Acinetobacter baumannii UH19908, Acinetobacter baumannii UH16208, Acinetobacter baumannii UH18608, Acinetobacter baumannii UH16108, Acinetobacter baumannii UH14508, Acinetobacter baumannii UH15208, Acinetobacter baumannii UH16008, Acinetobacter baumannii UH12808, Acinetobacter baumannii UH13908, Acinetobacter baumannii UH12208, Acinetobacter baumannii UH12408, Acinetobacter baumannii UH12308, Acinetobacter baumannii UH10007, Acinetobacter baumannii UH11608, Acinetobacter baumannii UH10107, Acinetobacter baumannii UH1007, Acinetobacter baumannii UH0807, Acinetobacter baumannii UH0207, Acinetobacter baumannii UH0707, Acinetobacter baumannii ZW85-1, Acinetobacter baumannii EGD-HP18, Acinetobacter baumannii 1605, Acinetobacter baumannii BJAB0868, Acinetobacter baumannii BJAB07104, Acinetobacter baumannii ANC 4097, Acinetobacter baumannii NIPH 290, Acinetobacter baumannii NIPH 70, Acinetobacter baumannii NIPH 528, Acinetobacter baumannii NIPH 601, Acinetobacter baumannii NIPH 67, Acinetobacter baumannii NIPH 329, Acinetobacter baumannii NIPH 527, Acinetobacter baumannii NIPH 201, Acinetobacter pittii ANC 3678, Acinetobacter nosocomialis NIPH 386, Acinetobacter baumannii NIPH 60, Acinetobacter baumannii NIPH 190, Acinetobacter baumannii NIPH 1734, Acinetobacter baumannii NIPH 2061, Acinetobacter baumannii NIPH 615, Acinetobacter baumannii NIPH 1362, Acinetobacter baumannii NIPH 1669, Acinetobacter baumannii NIPH 24, Acinetobacter baumannii ABNIH24, Acinetobacter baumannii ABNIH20, Acinetobacter baumannii ABNIH23, Acinetobacter baumannii ABNIH22, Acinetobacter baumannii ABNIH17, Acinetobacter baumannii ABNIH19, Acinetobacter baumannii ABNIH16, Acinetobacter baumannii ABNIH15, Acinetobacter baumannii ABNIH14, Acinetobacter baumannii ABNIH13, Acinetobacter baumannii ABNIH7, Acinetobacter baumannii ABNIH11, Acinetobacter baumannii ABNIH10, Acinetobacter baumannii ABNIH6, Acinetobacter baumannii ABNIH26, Acinetobacter baumannii D1279779, Acinetobacter baumannii MSP4-16, Acinetobacter baumannii Naval-57, Acinetobacter baumannii OIFC338, Acinetobacter baumannii OIFC047, Acinetobacter baumannii AA-014, Acinetobacter baumannii WC-A-92, Acinetobacter baumannii Naval-113, Acinetobacter baumannii WC-348, Acinetobacter baumannii WC-487, Acinetobacter baumannii OIFC035, Acinetobacter baumannii WC-A-694, Acinetobacter baumannii Canada BC1, Acinetobacter baumannii Naval-21, Acinetobacter baumannii OIFC111, Acinetobacter baumannii OIFC065, Acinetobacter baumannii Naval-83, Acinetobacter baumannii OIFC180, Acinetobacter baumannii Naval-13, Acinetobacter baumannii OIFC074, Acinetobacter baumannii IS-251, Acinetobacter baumannii IS-235, Acinetobacter baumannii OIFC0162, Acinetobacter baumannii Naval-72, Acinetobacter baumannii TYTH-1, Acinetobacter baumannii ZWS1219, Acinetobacter baumannii ZWS1122, Acinetobacter baumannii Ab11111, Acinetobacter baumannii Ab33333, Acinetobacter baumannii IS-58, Acinetobacter baumannii IS-116, Acinetobacter baumannii IS-143, Acinetobacter baumannii Naval-81, Acinetobacter baumannii IS-123, Acinetobacter baumannii Canada BC-5, Acinetobacter baumannii Naval-17, Acinetobacter baumannii OIFC109, Acinetobacter baumannii OIFC189, Acinetobacter baumannii OIFC137, Acinetobacter baumannii MDR-TJ, Acinetobacter baumannii ABNIH3, Acinetobacter baumannii ABNIH2, Acinetobacter baumannii AB210, Acinetobacter baumannii 6014059, Acinetobacter baumannii 6013113, Acinetobacter baumannii 6013150, Acinetobacter baumannii 1656-2, Acinetobacter baumannii AB307-0294, Acinetobacter baumannii AB0057, Acinetobacter baumannii ATCC 17978, Acinetobacter baumannii ACICU, Acinetobacter baumannii AYE Bacteria UP000036107, UP000036084, UP000036122, UP000036028, UP000036092, UP000036422, UP000036467, UP000028632, UP000030144, UP000029390, UP000028649, UP000027563, UP000027124, UP000027295, UP000027333, UP000027197, UP000027082, UP000027327, UP000027060, UP000027046, UP000027334, UP000027271, UP000027272, UP000027332, UP000006331, UP000007286, UP000023900, UP000023288, UP000022836, UP000020448, UP000020204, UP000023551, UP000020322, UP000020850, UP000023550, UP000021599, UP000021428, UP000020404, UP000020040, UP000021382, UP000022372, UP000022181, UP000022028, UP000020658, UP000022872, UP000022897, UP000019997, UP000023039, UP000020326, UP000020600, UP000022188, UP000022730, UP000021153, UP000020446, UP000022448, UP000022454, UP000021068, UP000023154, UP000023078, UP000022134, UP000022148, UP000022561, UP000022493, UP000020652, UP000021280, UP000020316, UP000021533, UP000021916, UP000021719, UP000023047, UP000021720, UP000021886, UP000020829, UP000023171, UP000020357, UP000021826, UP000023041, UP000023346, UP000020402, UP000021003, UP000020420, UP000022319, UP000022891, UP000021819, UP000021225, UP000020735, UP000020266, UP000020660, UP000021108, UP000020423, UP000021421, UP000022522, UP000020595, UP000020148, UP000021295, UP000022244, UP000023325, UP000019447, UP000019044, UP000019055, UP000018973, UP000018907, UP000018918, UP000018916, UP000018977, UP000018930, UP000018903, UP000018939, UP000018928, UP000018964, UP000018972, UP000018961, UP000018947, UP000018970, UP000018915, UP000018943, UP000018913, UP000018923, UP000018944, UP000018906, UP000018938, UP000018904, UP000018933, UP000018946, UP000018976, UP000018974, UP000018932, UP000018911, UP000018926, UP000018908, UP000018983, UP000018940, UP000018921, UP000018937, UP000018931, UP000018981, UP000018900, UP000018969, UP000018968, UP000018905, UP000018954, UP000018982, UP000018984, UP000018941, UP000018956, UP000018962, UP000018698, UP000016517, UP000015342, UP000014808, UP000014810, UP000013269, UP000013153, UP000013212, UP000013135, UP000013068, UP000013241, UP000013103, UP000013235, UP000013023, UP000013256, UP000013028, UP000013288, UP000013284, UP000013040, UP000013215, UP000013061, UP000013214, UP000013223, UP000013203, UP000012221, UP000012218, UP000012407, UP000012402, UP000012321, UP000012341, UP000012387, UP000012241, UP000012307, UP000012416, UP000012318, UP000012201, UP000012401, UP000012189, UP000012413, UP000011860, UP000011734, UP000011642, UP000011662, UP000011639, UP000011622, UP000011533, UP000009878, UP000009870, UP000009890, UP000002840, UP000002838, UP000002850, UP000002834, UP000002836, UP000002839, UP000007976, UP000007825, UP000007989, UP000007981, UP000007977, UP000007823, UP000007831, UP000007822, UP000006297, UP000006758, UP000006754, UP000005796, UP000010298, UP000005378, UP000005399, UP000006088, UP000006267, UP000006953, UP000006973, UP000001081, UP000008950, UP000008758, UP000006515, UP000009146, UP000004880, UP000004472, UP000003466, UP000003204, UP000006411, UP000002932, UP000008976, UP000006924, UP000007094, UP000006737, UP000008839, UP000002446 446995605, 831414527, 831410450, 831405271, 831404779, 831393289, 831392599, 831390913, 827407273, 815873871, 807204168, 807142483, 803359145, 787862355, 767769062, 767586541, 767555779, 765633456, 765630037, 765627023, 765621301, 765514922, 765511817, 765507963, 765499728, 765498899, 763963929, 763961836, 763957312, 763951980, 763945607, 763942247, 763938186, 763933329, 763930746, 763926604, 763923411, 763919062, 756553015, 751411097, 749398416, 743003105, 741853507, 741853408, 741849262, 741844588, 741841652, 741838273, 741831897, 741829312, 741826671, 741820071, 741819450, 741816193, 741812334, 741805879, 741801017, 741799539, 741794652, 741790548, 741789855, 741784738, 741780400, 741778744, 741771565, 741769269, 741765437, 741757326, 741752799, 741750883, 741744168, 741740580, 741734743, 741731124, 741727437, 741726326, 741719757, 741713681, 741712996, 741707917, 741701405, 741698574, 741695353, 741693765, 741689101, 741685465, 741682315, 741671035, 741670964, 741667661, 741665497, 741661068, 741658605, 741651215, 741647777, 741644220, 741642176, 741633883, 741631689, 741624635, 741620858, 741615761, 741614339, 741610651, 741607970, 741600455, 741594399, 741593593, 741584852, 741584418, 741583681, 741575668, 741573038, 741569484, 741565049, 741563189, 741558691, 741552466, 741549374, 741544121, 741539758, 741537368, 741536726, 741527368, 741526946, 741521682, 741520600, 741513910, 741511218, 741505266, 741500862, 741498419, 741491159, 741490855, 741482737, 741482124, 741476052, 741473931, 741469576, 741457955, 741450590, 741445287, 741440430, 741437315, 741433124, 741429330, 741429254, 741424435, 741415792, 741412172, 741408601, 741404274, 741399860, 741398434, 741394187, 741391491, 741386071, 741383805, 741378567, 741377001, 741370739, 741363158, 741359823, 741356000, 741355078, 741346767, 741343047, 741341968, 741332792, 741329744, 741317504, 741309543, 741306737, 741302609, 741299937, 741295064, 741290862, 741287084, 741282412, 741279969, 741277342, 741270133, 741269612, 741265637, 741258237, 741253895, 741249756, 701449200, 692328850, 691195558, 686062506, 675330504, 675324750, 668716486, 668668610, 640864517, 635721711, 630645380, 630638995, 630589059, 630533283, 630527517, 630513816, 630511892, 630500982, 630460086, 630451957, 630400938, 629031378, 615559063, 613738682, 607874944, 604708034, 601427002, 601425736, 601421173, 601417253, 601413080, 601408680, 601404226, 593845058, 593835945, 593830176, 593825728, 593821866, 593816096, 593813617, 593682471, 593649081, 593612940, 593598487, 593593184, 593561713, 593542367, 593506134, 593492274, 589556987, 589548656, 589532825, 589509923, 589506768, 589500237, 589499620, 589466007, 589459599, 589452814, 589426613, 589404325, 589190007, 589181225, 589155033, 589153136, 588248052, 588200651, 588187465, 588168004, 588164822, 588158811, 588147131, 588144046, 588133974, 588131132, 588126896, 588086707, 588060437, 588034761, 588016688, 588004899, 587996358, 587985900, 587967513, 587941699, 587929124, 587920139, 587850968, 587845334, 587819068, 587815301, 587803277, 587794845, 587765742, 587762705, 586958453, 573038240, 573035263, 572038251, 571774975, 571773470, 571770386, 571763321, 571761407, 571756729, 571754856, 571747591, 571744382, 571741816, 571732322, 571731179, 571729043, 571725819, 571714806, 571710012, 571706155, 571704591, 571700849, 571696911, 571687584, 571686983, 571676299, 571675011, 571674633, 571668819, 571666727, 571661766, 571650878, 571649600, 571647862, 571639769, 571637047, 571634804, 571632962, 571627949, 571626595, 571619339, 571613580, 571611962, 571606935, 571606345, 571602592, 571596071, 571587543, 571582918, 571580795, 564742427, 542023429, 527237206, 522344753, 522324884, 480136049, 480134288, 480123205, 480121678, 480120989, 480111747, 480110326, 480104049, 480096592, 480094847, 480075369, 480000446, 479985715, 479980691, 479928458, 479927157, 479922779, 479904586, 479899983, 479859793, 475990873, 475984505, 475983157, 475977801, 475969894, 475964885, 475956716, 475954796, 475947664, 475943435, 475939218, 475937827, 475932899, 475925683, 475921998, 469493948, 452954156, 444784080, 444780578, 444770862, 444768185, 444759099, 425496574, 425487982, 425484383, 410417660, 410414736, 410410218, 410397931, 410389367, 410386232, 408708690, 408705415, 408703772, 408692572, 408516826, 408515168, 408512522, 408506382, 407899780, 407195148, 407194759, 404667469, 404666560, 404571087, 404565669, 404564245, 400392066, 400210420, 400205735, 395569318, 395562966, 395551590, 395523815, 385879985, 342227013, 342225262, 333364523, 332736865, 332734427, 332729935, 322506481, 260410429, 213987511, 213054864, 193076119, 183208188, 846382730, 808173614, 808168985, 808163862, 693581509, 238691016, 238688101, 238685489, 226695512, 226695511, 169150409 KLT99611.1, KLT95603.1, KLT90487.1, KLT90000.1, KLT78656.1, KLT77982.1, KLT76316.1, AKJ47432.1, KKI95899.1, KKD27288.1, KKD18444.1, KKA97427.1, AKA33310.1, KJG92575.1, KJG81420.1, KJG75664.1, KJF14910.1, KJF11610.1, KJF08735.1, KJF03553.1, KJE73640.1, KJE70578.1, KJE66833.1, KJE58876.1, KJE58063.1, KJD11324.1, KJD09266.1, KJD04887.1, KJC99706.1, KJC93581.1, KJC90317.1, KJC86385.1, KJC81669.1, KJC79152.1, KJC75198.1, KJC72080.1, KJC67847.1, KIQ71664.1, AJF80258.1, KII23400.1, AJB68525.1, KIA54696.1, KIA54598.1, KIA50581.1, KIA46015.1, KIA43135.1, KIA39866.1, KIA33689.1, KIA31169.1, KIA28598.1, KIA22424.1, KIA21831.1, KIA18585.1, KIA14878.1, KIA08560.1, KIA03796.1, KIA02345.1, KHZ97600.1, KHZ93632.1, KHZ92949.1, KHZ87966.1, KHZ83699.1, KHZ82062.1, KHZ75272.1, KHZ73000.1, KHZ69209.1, KHZ61327.1, KHZ56889.1, KHZ55045.1, KHZ48487.1, KHZ44999.1, KHZ39506.1, KHZ35991.1, KHZ32505.1, KHZ31417.1, KHZ24970.1, KHZ19086.1, KHZ18416.1, KHZ13499.1, KHZ07157.1, KHZ04412.1, KHZ01290.1, KHY99763.1, KHY95278.1, KHY91726.1, KHY88654.1, KHY77623.1, KHY77553.1, KHY74329.1, KHY72246.1, KHY67960.1, KHY65560.1, KHY58384.1, KHY55040.1, KHY51584.1, KHY49613.1, KHY41564.1, KHY39396.1, KHY32588.1, KHY28886.1, KHY24049.1, KHY22718.1, KHY19136.1, KHY16488.1, KHY09219.1, KHY03257.1, KHY02474.1, KHX93977.1, KHX93547.1, KHX92823.1, KHX85202.1, KHX82618.1, KHX79166.1, KHX74868.1, KHX73048.1, KHX68684.1, KHX62751.1, KHX59779.1, KHX54768.1, KHX50812.1, KHX48551.1, KHX47925.1, KHX38884.1, KHX38472.1, KHX33475.1, KHX32414.1, KHX26030.1, KHX23397.1, KHX17730.1, KHX13658.1, KHX11273.1, KHX04344.1, KHX04046.1, KHW96232.1, KHW95629.1, KHW89818.1, KHW87761.1, KHW83680.1, KHW72798.1, KHW65695.1, KHW60540.1, KHW55966.1, KHW52930.1, KHW48814.1, KHW45288.1, KHW45214.1, KHW40477.1, KHW32345.1, KHW28833.1, KHW25347.1, KHW21183.1, KHW16886.1, KHW15493.1, KHW11405.1, KHW08845.1, KHW03528.1, KHW01318.1, KHV96240.1, KHV94707.1, KHV88718.1, KHV81359.1, KHV78206.1, KHV74434.1, KHV73526.1, KHV65613.1, KHV62149.1, KHV61096.1, KHV52537.1, KHV49731.1, KHV38768.1, KHV31047.1, KHV28460.1, KHV24471.1, KHV21855.1, KHV17149.1, KHV13023.1, KHV09443.1, KHV04933.1, KHV02572.1, KHT99999.1, KHT92986.1, KHT92477.1, KHT88587.1, KHT81410.1, KHT77339.1, KHT73338.1, KGP64534.1, AIS05051.1, KGF58575.1, KGB48827.1, AIL80024.1, AIL74271.1, KFC02121.1, KFB64275.1, AIA53614.1, KDF03512.1, KCZ38387.1, KCZ32810.1, KCY91376.1, KCY40353.1, KCY34978.1, KCY22104.1, KCY20236.1, KCY09920.1, KCX73764.1, KCX66204.1, KCX20006.1, KCW28798.1, AHX66587.1, AHX29028.1, EZF20137.1, EYU52932.1, EYS74849.1, EYS73631.1, EYS69392.1, EYS65592.1, EYS61541.1, EYS57292.1, EYS52971.1, EXT02831.1, EXS94041.1, EXS88608.1, EXS84312.1, EXS80594.1, EXS74990.1, EXS72618.1, EXS60967.1, EXS29038.1, EXR94373.1, EXR80380.1, EXR75380.1, EXR45162.1, EXR26504.1, EXQ91685.1, EXQ78249.1, EXI36010.1, EXI27961.1, EXI12619.1, EXH90359.1, EXH87239.1, EXH80877.1, EXH80281.1, EXH47980.1, EXH41803.1, EXH35296.1, EXH10625.1, EXG88957.1, EXG35013.1, EXG26471.1, EXG00908.1, EXF99041.1, EXF19755.1, EXE73744.1, EXE61160.1, EXE42169.1, EXE39088.1, EXE33401.1, EXE22311.1, EXE19383.1, EXE09952.1, EXE07213.1, EXE03087.1, EXD66843.1, EXD41755.1, EXD17203.1, EXC99805.1, EXC88460.1, EXC80160.1, EXC70312.1, EXC52559.1, EXC28264.1, EXC16297.1, EXC07585.1, EXB41122.1, EXB35887.1, EXB10312.1, EXB06912.1, EXA95493.1, EXA87388.1, EXA60093.1, EXA57271.1, AHJ91748.1, ETS70188.1, ETS67319.1, ETR91950.1, ETR61859.1, ETR60414.1, ETR57370.1, ETR50437.1, ETR48549.1, ETR44075.1, ETR42270.1, ETR35238.1, ETR32122.1, ETR29610.1, ETR20512.1, ETR19416.1, ETR17386.1, ETR14276.1, ETR03668.1, ETQ98993.1, ETQ95239.1, ETQ93748.1, ETQ90132.1, ETQ86328.1, ETQ77235.1, ETQ76656.1, ETQ66437.1, ETQ65214.1, ETQ64864.1, ETQ59220.1, ETQ57216.1, ETQ52424.1, ETQ41943.1, ETQ40705.1, ETQ39012.1, ETQ31205.1, ETQ28576.1, ETQ26397.1, ETQ24621.1, ETQ19761.1, ETQ18456.1, ETQ11399.1, ETQ05816.1, ETQ04272.1, ETP99413.1, ETP98850.1, ETP95228.1, ETP88944.1, ETP80795.1, ETP76345.1, ETP74312.1, AHB92923.1, ERH69110.1, EPS75705.1, AGQ08872.1, AGQ12687.1, ENW73365.1, ENW71675.1, ENW60860.1, ENW59402.1, ENW58714.1, ENW49616.1, ENW48220.1, ENW42066.1, ENW34733.1, ENW33025.1, ENW14058.1, ENV42718.1, ENV28966.1, ENV24363.1, ENU76002.1, ENU74797.1, ENU70692.1, ENU53757.1, ENU49442.1, ENU11967.1, EMU51356.1, EMU47331.1, EMU46084.1, EMU41709.1, EMU35540.1, EMU30820.1, EMU23199.1, EMU21340.1, EMU14796.1, EMU10775.1, EMU07066.1, EMU05871.1, EMU01362.1, EMT94823.1, EMT91332.1, AGH34126.1, EME59560.1, ELX07911.1, ELX04523.1, ELW94999.1, ELW92404.1, ELW83583.1, EKU62700.1, EKU54323.1, EKU50788.1, EKP69429.1, EKP66532.1, EKP62134.1, EKP50166.1, EKP41781.1, EKP38705.1, EKL53962.1, EKL50756.1, EKL49154.1, EKL38190.1, EKK18385.1, EKK16760.1, EKK14163.1, EKK08093.1, AFU36611.1, EKE66282.1, EKE65895.1, EKB35390.1, EKB34503.1, EKA76152.1, EKA70833.1, EKA69427.1, EJP59113.1, EJO41389.1, EJO36715.1, EJG29980.1, EJG24619.1, EJG17599.1, EJG11904.1, AFI97080.1, EGT91962.1, EGT90262.1, EGK46537.1, EGJ67841.1, EGJ65547.1, EGJ61266.1, ADX01935.1, EEX03728.1, ACJ57810.1, ACJ39766.1, ABO10726.2, ACC55586.1 WP_001072861.1 B7H1M6, B7I331, B2I1W2, A3M1D2, B0VDF1 THIC_ACIB3, THIC_ACIB5, THIC_ACIBC, THIC_ACIBT, THIC_ACIBY Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5211841, 10492658, 5222485, 5215662, 3627594, 5752366 fig|992404.3.peg.3274, fig|1168590.3.peg.3325, fig|903896.3.peg.1493, fig|557600.3.peg.3160, fig|1221287.3.peg.1517, fig|1094474.3.peg.2883, fig|1094488.3.peg.664, fig|903917.3.peg.3835, fig|1286087.3.peg.1035, fig|1221254.3.peg.3717, fig|1286088.3.peg.3270, fig|903933.3.peg.3317, fig|903908.3.peg.2661, fig|886886.3.peg.2810, fig|981329.3.peg.1989, fig|903895.3.peg.3590, fig|1217628.3.peg.3227, fig|1221256.3.peg.1087, fig|1221268.3.peg.3081, fig|525243.3.peg.879, fig|1217644.3.peg.3329, fig|903925.3.peg.51, fig|1217673.3.peg.166, fig|1221249.3.peg.498, fig|1221248.3.peg.236, fig|1221288.3.peg.3507, fig|1221271.3.peg.2874, fig|945556.3.peg.419, fig|1222031.3.peg.2179, fig|903914.3.peg.2311, fig|903920.3.peg.3367, fig|1221250.3.peg.81, fig|1221253.3.peg.23, fig|1217636.3.peg.277, fig|1168588.3.peg.3611, fig|557601.3.peg.1361, fig|1216295.3.peg.292, fig|1286086.3.peg.2269, fig|1116236.3.peg.1451, fig|1217627.3.peg.3405, fig|1221276.3.peg.211, fig|710094.4.peg.1881, fig|525242.3.peg.631, fig|1293574.3.peg.3060, fig|1198108.3.peg.2353, fig|903906.3.peg.1533, fig|1094479.3.peg.1163, fig|1224747.3.peg.3082, fig|1094480.3.peg.1718, fig|903901.3.peg.3745, fig|903894.3.peg.3009, fig|903904.3.peg.3094, fig|1217646.3.peg.3355, fig|1221246.3.peg.2209, fig|1224166.3.peg.516, fig|1210907.3.peg.2670, fig|1221266.3.peg.3470, fig|1221275.3.peg.1567, fig|1217630.3.peg.3465, fig|1221259.3.peg.486, fig|696749.3.peg.304, fig|1094477.3.peg.1723, fig|1217641.3.peg.794, fig|1094484.3.peg.838, fig|903898.3.peg.580, fig|1279013.3.peg.450, fig|1217640.3.peg.3399, fig|1221292.3.peg.4, fig|992403.3.peg.3051, fig|1221272.3.peg.2528, fig|1217985.3.peg.444, fig|349747.9.peg.1886, fig|1221251.3.peg.618, fig|903919.3.peg.2436, fig|400667.4.peg.265, fig|575584.3.peg.1939, fig|1217631.3.peg.3455, fig|903907.3.peg.326, fig|502800.3.peg.1623, fig|903912.3.peg.23, fig|405416.6.peg.373, fig|1221262.3.peg.346, fig|903937.3.peg.837, fig|1116234.3.peg.985, fig|480119.5.peg.338, fig|1217642.3.peg.2669, fig|1278070.3.peg.520, fig|1221273.3.peg.1110, fig|903911.3.peg.1856, fig|592014.3.peg.1845, fig|1094475.3.peg.133, fig|509173.8.peg.3374, fig|886889.3.peg.430, fig|1217645.3.peg.273, fig|903926.3.peg.101, fig|1217635.3.peg.3443, fig|1217632.3.peg.3326, fig|903934.3.peg.34, fig|1221265.3.peg.2338, fig|981224.3.peg.23, fig|1286084.3.peg.2645, fig|903903.3.peg.1192, fig|903924.3.peg.661, fig|903909.3.peg.2080, fig|903889.3.peg.2969, fig|945555.3.peg.3316, fig|1286089.3.peg.1, fig|889738.3.peg.3693, fig|903899.3.peg.3185, fig|1223564.3.peg.398, fig|1094481.3.peg.1061, fig|903892.3.peg.3047, fig|1094487.3.peg.888, fig|1217638.3.peg.286, fig|1221286.3.peg.3565, fig|981328.3.peg.350, fig|1116233.3.peg.1325, fig|1221290.3.peg.2383, fig|1221245.3.peg.3512, fig|497978.4.peg.304, fig|886888.3.peg.2978, fig|903931.3.peg.1889, fig|1217647.3.peg.2843, fig|1094486.3.peg.1107, fig|1217643.3.peg.3356, fig|903927.3.peg.26, fig|1222033.3.peg.1220, fig|1224141.3.peg.326, fig|903935.3.peg.3702, fig|1221277.3.peg.1668, fig|1221264.3.peg.3640, fig|903923.3.peg.2171, fig|980514.3.peg.314, fig|1100841.3.peg.528, fig|903932.3.peg.542, fig|1094471.3.peg.58, fig|1217637.3.peg.3302, fig|1221267.3.peg.2100, fig|1221270.3.peg.1485, fig|1094483.3.peg.1819, fig|903905.3.peg.79, fig|1094470.3.peg.2681, fig|1222032.3.peg.1613, fig|1094478.3.peg.1319 621 625 yes 438023 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 220341, 28901, 1443995, 527001, 1132507, 209261, 90370, 149539, 90371 Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica, Salmonella enterica subsp. enterica serovar Typhi str. STH2370, Salmonella enterica subsp. enterica serovar Typhi str. Ty21a, Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12, Salmonella enterica subsp. enterica serovar Typhi str. Ty2, Salmonella enterica subsp. enterica serovar Typhi, Salmonella enterica subsp. enterica serovar Enteritidis, Salmonella enterica subsp. enterica serovar Typhimurium Bacteria UP000054489, UP000022615, UP000013302, UP000007169, UP000050089, UP000034332, UP000028938 16762293, 446030570, 576305086, 485083604, 374355505, 29139416, 857928269, 857920926, 857838082, 857831726, 857817767, 857800105, 857780629, 857768727, 857762408, 857755820, 857749412, 857743011, 857736610, 857730253, 857723850, 857717621, 857706771, 857700613, 857694418, 857682016, 857676314, 857670040, 857663921, 857657811, 857652078, 857647515, 857620551, 814617665, 814294372, 814284298, 814279284, 814274547, 814269740, 814264955, 814260081, 814250519, 814245733, 814240847, 814236024, 814231194, 814226313, 814221606, 814216767, 814211887, 814207094, 814202254, 814197436, 814192631, 814187694, 814182972, 814178096, 814173335, 814168399, 814163659, 814158870, 814154062, 814149133, 814144395, 814139657, 814134738, 814129941, 814120656, 814115836, 814111069, 814106217, 814101448, 814096584, 814091810, 814086985, 814082081, 814081441, 814072497, 814066882, 814062046, 814057222, 814052433, 814047509, 814042795, 814037922, 814033099, 814028221, 814027542, 814018692, 814013865, 814009067, 813999491, 813994666, 813989974, 813985050, 813980271, 813975449, 813970678, 813961086, 813959582, 813951486, 813950683, 813937031, 813932212, 813927342, 813922598, 813917821, 813903406, 813898561, 813884152, 813860621, 813855868, 813851085, 813846281, 813837064, 813832365, 813827731, 813822990, 813818222, 813817369, 813808582, 813803852, 813799314, 813794304, 813789604, 813784856, 813780069, 813775329, 813770619, 813765881, 813761161, 813756470, 813751688, 813746990, 813742232, 813737585, 813733094, 813728258, 813723535, 813718885, 813714322, 813709474, 813704778, 813700149, 813695424, 813690695, 813686043, 813681668, 813676601, 813672137, 813667330, 813662716, 813657992, 813657052, 813648634, 813644034, 813639286, 813634581, 813630019, 813625276, 813620769, 813615925, 813611422, 813606777, 813605988, 813597439, 813592804, 813588198, 813587435, 813578815, 813574045, 813569475, 813564760, 813560268, 813554537, 813550035, 813545121, 813540485, 813535899, 813531424, 813526878, 813522058, 813512880, 813508207, 813503608, 813499112, 813498050, 813489852, 813485184, 813480628, 813475935, 813471331, 813466746, 813462155, 813457538, 813452812, 813448277, 813443649, 813439044, 813434351, 813434153, 813424510, 813419055, 813414470, 813409874, 813405301, 813400731, 813396086, 813391504, 813386912, 813382321, 813377739, 813373171, 813368543, 813363975, 813359359, 813354664, 813350165, 813345568, 813341012, 813336394, 813335667, 813327194, 813322647, 813318056, 813313387, 813308817, 813304210, 813299588, 813295094, 813293940, 813285830, 813281175, 813276664, 813275958, 813267441, 813262866, 813258229, 813253349, 813247902, 813243024, 813240139, 813233860, 813227886, 813220512, 813210200, 813200505, 813193157, 813179306, 813172347, 813165582, 813158352, 813151213, 813143753, 813136173, 813128215, 813119953, 813111768, 813103698, 813096562, 813091127, 813085396, 813079816, 813074026, 813068291, 813063238, 813058657, 813054092, 813049497, 813040269, 813031107, 813021887, 813017342, 813012741, 813008189, 813003576, 812998996, 812994376, 812989823, 812988639, 812980659, 812976082, 812971484, 812966855, 812962334, 812957749, 812953153, 812948527, 812939413, 812934869, 812930300, 812925681, 812920913, 812915953, 812911129, 812906183, 812901294, 812896451, 812891518, 812886601, 812881810, 812877095, 812872414, 812867777, 812863090, 812858610, 812854029, 812849374, 812844800, 812840220, 812837698, 812831097, 812826408, 812821943, 812817332, 812812745, 812808218, 812803640, 812799072, 812794472, 812789943, 812785350, 812780757, 812776205, 812771616, 812767090, 812762507, 812757951, 812753392, 812748732, 812744256, 812739693, 812735141, 812730565, 812725976, 812721338, 812716864, 812712228, 812707727, 812703151, 812698553, 812693975, 812689425, 812684843, 812671404, 812666845, 812657678, 812653078, 812648479, 812643941, 812639370, 812634753, 812630253, 812625679, 812621094, 812616530, 812611902, 812607396, 812603245, 812598279, 812593697, 812589114, 812584575, 812580014, 812575425, 812570873, 812566540, 812561849, 812557214, 812552714, 812548132, 812543551, 812538988, 812538735, 812529648, 812528211, 812520529, 812515931, 812511380, 812506761, 812502233, 812497649, 812493063, 812488520, 812483960, 812479382, 812474764, 812470229, 812465658, 812461125, 812456611, 812452061, 812447430, 812442881, 812438355, 812433801, 812429196, 812424644, 812420121, 812415533, 812411019, 812406448, 812397310, 812392712, 812379341, 812374836, 812370313, 812365667, 812361179, 812356630, 812352038, 812347522, 812343036, 812338468, 812333926, 812333247, 812324819, 812320281, 812315757, 812311152, 812306661, 812302135, 812299899, 812293000, 812288529, 812283970, 812276681, 812270369, 812269618, 812261294, 812252618, 812248021, 812243530, 812234884, 812230386, 812224421, 812212510, 812199765, 812193571, 812180985, 812161220, 812153381, 806757536, 806752722, 806747811, 806743151, 806738629, 806734058, 806729482, 806725014, 805231158, 805212243, 805194665, 804956176, 804951316, 804946767, 804937475, 804932906, 804928197, 804923312, 804918579, 804913655, 804908721, 804903815, 804898980, 804894230, 804889501, 804884811, 804879928, 804875225, 804870547, 804865732, 804861028, 804856345, 804851787, 804847086, 804842310, 804837535, 804832622, 804827827, 804822969, 804818185, 804813346, 804808544, 804803706, 804798876, 804794207, 804789440, 804784819, 804780053, 804775135, 804770269, 804765359, 804760359, 804755762, 804751204, 804746675, 804741834, 804737001, 804732235, 804727546, 804722756, 804717933, 804712995, 804708080, 804703110, 804698198, 804693540, 804688726, 804683786, 804678933, 804673955, 804669253, 804664295, 804659502, 804654798, 804649767, 804644925, 804639911, 804635144, 804630207, 804625482, 804620626, 804615805, 804611079, 804606215, 804601394, 804596620, 804591864, 804586972, 804582128, 804577302, 804572506, 804567931, 804563280, 804558723, 804554104, 804549363, 804544644, 804539848, 804535156, 804530494, 804525760, 804521077, 804516279, 804511729, 804507046, 804502378, 804497528, 804492736, 804487897, 804483091, 804478506, 804473759, 804469025, 804464347, 804459595, 804454719, 804449897, 804445022, 804440141, 804435499, 804430668, 804425953, 804421274, 804416479, 804411618, 804406672, 804401857, 804397009, 804392234, 804387432, 804382588, 804377794, 804372843, 804368048, 804363117, 804358306, 804353481, 804348622, 804343638, 804338757, 804333943, 804329258, 804324340, 804319512, 804314531, 804309910, 804305319, 804300525, 804295700, 804290852, 804286173, 804281416, 804276490, 804270564, 804264512, 804258604, 804252709, 804246526, 804239825, 804233620, 804227034, 804220687, 804214491, 804208343, 804202079, 804196082, 804189310, 804182942, 804176707, 804170619, 804164429, 804158190, 804151850, 804145498, 804139085, 804132786, 804126627, 804120121, 804114234, 804108176, 804102163, 804096039, 804089844, 804083511, 804077232, 801020928, 801015750, 801010244, 801004826, 800999415, 800994088, 799743142, 799738525, 799734022, 799729341, 799724608, 799719963, 799715308, 799710499, 799705742, 799701001, 799696197, 799691321, 799686649, 799681620, 799676915, 799676222, 799667560, 771183038, 771156244, 771133116, 771114924, 771092807, 771073159, 771046115, 771021457, 770997298, 770976178, 770957127, 770944203, 770942221, 770933791, 770928654, 770923701, 770918492, 770913586, 770908616, 770903237, 770898255, 770893495, 770888683, 770883897, 770879308, 770878057, 770869179, 770863795, 770858580, 770857014, 770847515, 770842216, 770836827, 770832012, 770830912, 770821050, 770816028, 770810167, 770804302, 770798416, 770792060, 770785944, 770780256, 770774807, 770769732, 770764951, 770760142, 770754889, 770750202, 770745156, 770740160, 770734505, 770728594, 770723429, 770722301, 770713467, 770703733, 770698820, 770689779, 25319677, 21759455, 16504597 ETZ13806.1, AGK68983.1, AEZ47266.1, AAO70983.1 NP_457910.1, WP_000108425.1 Q8Z326 THIC_SALTI Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 155137, 6482934, 6449121, 6504842, 348443, 6463358 fig|1169661.3.peg.1603, fig|1192853.3.peg.1740, fig|1169660.3.peg.3463, fig|527001.3.peg.3687, fig|1156917.3.peg.3667, fig|209261.1.peg.3233, fig|497974.4.peg.1886, fig|1176488.3.peg.2849, fig|220341.1.peg.3300, fig|1176487.3.peg.2690, fig|1132507.4.peg.3696, fig|496064.4.peg.3081 626 631 yes 438024 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 533, 395963 Beijerinckia indica, Beijerinckia indica subsp. indica ATCC 9039 Bacteria UP000001695 501351445, 182632948 ACB93722.1 WP_012383080.1 fig|395963.13.peg.296 614 614 yes 438025 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 99287, 28901, 90371, 59201, 1454627, 1454642, 796733, 796731, 796732, 796730, 858307, 1454639, 858305, 1124970, 858308, 858306, 1387345, 1387341, 1387333, 1387331, 1387339, 1302616, 1173929, 1410932, 1194150, 1029978, 702980, 1037262, 1124973, 1124972, 1124971, 1352603, 877468, 1271862, 1171376, 1275975, 1275977, 1159899, 1159900, 866915, 866914, 1218153, 1218152, 1218151, 1218150, 1218147, 1218146, 1218145, 1218149, 1218148, 1218144, 1218143, 858312, 859197, 859196, 858311, 858310, 858309, 796736, 796735, 796737, 1008297, 909946, 946034, 423368, 85569, 996633, 568709, 718274, 216597, 568708 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica, Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Newport str. USDA-ARS-USMARC-1934, Salmonella enterica subsp. enterica serovar Typhimurium str. USDA-ARS-USMARC-1909, Salmonella enterica subsp. enterica serovar Newport str. CVM 21550, Salmonella enterica subsp. enterica serovar Newport str. CVM 21538, Salmonella enterica subsp. enterica serovar Newport str. CVM 22513, Salmonella enterica subsp. enterica serovar Newport str. CVM 22425, Salmonella enterica subsp. enterica serovar Newport str. CVM N1543, Salmonella enterica subsp. enterica serovar Typhimurium str. USDA-ARS-USMARC-1899, Salmonella enterica subsp. enterica serovar Newport str. CVM 22462, Salmonella enterica subsp. enterica serovar Typhimurium str. 86-0368, Salmonella enterica subsp. enterica serovar Newport str. CVM 21554, Salmonella enterica subsp. enterica serovar Newport str. CVM N18486, Salmonella enterica subsp. enterica serovar Typhimurium str. 116015, Salmonella enterica subsp. enterica serovar Typhimurium str. 108402, Salmonella enterica subsp. enterica serovar Typhimurium str. 98346, Salmonella enterica subsp. enterica serovar Typhimurium str. 95799, Salmonella enterica subsp. enterica serovar Typhimurium str. 104772, Salmonella enterica subsp. enterica serovar Aqua str. NVSL2001, Salmonella enterica subsp. enterica serovar Typhimurium var. Copenhagen str. 0084, Salmonella enterica subsp. enterica serovar Give var. 15 str. CFSAN004343, Salmonella enterica subsp. enterica serovar Litchfield str. CFSAN001076, Salmonella enterica subsp. enterica serovar Typhimurium str. SARA13, Salmonella enterica subsp. enterica serovar Typhimurium str. ST4581, Salmonella enterica subsp. enterica serovar Typhimurium str. AZ 057, Salmonella enterica subsp. enterica serovar Typhimurium str. 36618, Salmonella enterica subsp. enterica serovar Typhimurium str. 35423, Salmonella enterica subsp. enterica serovar Typhimurium str. 34502, Salmonella enterica subsp. enterica serovar Typhimurium str. STm7, Salmonella enterica subsp. enterica serovar Newport str. USMARC-S3124.1, Salmonella enterica subsp. enterica serovar Typhimurium var. 5- str. CFSAN001921, Salmonella enterica subsp. enterica serovar Typhimurium str. U288, Salmonella enterica subsp. enterica serovar Newport str. Henan_3, Salmonella enterica subsp. enterica serovar Newport str. Shandong_3, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2-4, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2-4_delta.ramA::kan, Salmonella enterica subsp. enterica serovar 4,[5],12:i:- str. 08-1739, Salmonella enterica subsp. enterica serovar 4,[5],12:i:- str. 08-1700, Salmonella enterica subsp. enterica serovar Typhimurium str. STm5, Salmonella enterica subsp. enterica serovar Typhimurium str. STm12, Salmonella enterica subsp. enterica serovar Typhimurium str. STm11, Salmonella enterica subsp. enterica serovar Typhimurium str. STm10, Salmonella enterica subsp. enterica serovar Typhimurium str. STm6, Salmonella enterica subsp. enterica serovar Typhimurium str. STm4, Salmonella enterica subsp. enterica serovar Typhimurium str. STm3, Salmonella enterica subsp. enterica serovar Typhimurium str. STm9, Salmonella enterica subsp. enterica serovar Typhimurium str. STm8, Salmonella enterica subsp. enterica serovar Typhimurium str. STm2, Salmonella enterica subsp. enterica serovar Typhimurium str. STm1, Salmonella enterica subsp. enterica serovar Newport str. CVM 19470, Salmonella enterica subsp. enterica serovar Newport str. CVM 4176, Salmonella enterica subsp. enterica serovar Newport str. CVM 19536, Salmonella enterica subsp. enterica serovar Newport str. CVM 19593, Salmonella enterica subsp. enterica serovar Newport str. CVM 37978, Salmonella enterica subsp. enterica serovar Newport str. CVM 19443, Salmonella enterica subsp. enterica serovar Newport str. CVM 19449, Salmonella enterica subsp. enterica serovar Newport str. CVM 19567, Salmonella enterica subsp. enterica serovar Newport str. CVM 19447, Salmonella enterica subsp. enterica serovar Typhimurium str. 798, Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74, Salmonella enterica subsp. enterica serovar Typhimurium str. TN061786, Salmonella enterica subsp. enterica serovar Newport str. SL254, Salmonella typhimurium DT104, Salmonella enterica subsp. enterica serovar Typhimurium str. L-3553, Salmonella enterica subsp. enterica serovar Typhimurium str. DT2, Salmonella enterica subsp. enterica serovar Typhimurium str. T000240, Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344, Salmonella enterica subsp. enterica serovar Typhimurium str. D23580 Bacteria UP000001014 UP000001014, UP000054489, UP000028938, UP000033855, UP000033105, UP000033036, UP000005062, UP000006029, UP000004429, UP000004825, UP000005053, UP000032269, UP000005504, UP000030396, UP000004413, UP000005928, UP000026384, UP000026376, UP000025599, UP000026351, UP000025770, UP000024824, UP000018578, UP000018537, UP000017443, UP000017458, UP000017308, UP000017375, UP000017089, UP000017080, UP000017130, UP000021567, UP000015284, UP000014938, UP000013001, UP000011780, UP000011775, UP000028614, UP000028609, UP000018003, UP000018288, UP000009349, UP000009362, UP000009347, UP000009334, UP000009332, UP000009363, UP000009350, UP000009333, UP000009345, UP000009335, UP000009353, UP000005409, UP000004815, UP000005717, UP000004193, UP000004397, UP000003733, UP000006418, UP000003668, UP000005470, UP000007588, UP000008978, UP000004422, UP000008824, UP000048618, UP000031639, UP000016890, UP000016782, UP000008962, UP000002622 16767418, 446030558, 855231429, 846509534, 846509204, 846498909, 846477818, 846475812, 846463763, 844669042, 844664663, 844660466, 844565555, 844563229, 844562102, 831267759, 831259273, 831257985, 831256825, 830232858, 821165697, 808278616, 808246980, 808231417, 808202208, 808186669, 767850835, 767846544, 767841607, 767837574, 767829981, 764057783, 744791705, 724769518, 696595396, 696582821, 674285006, 619521913, 619519545, 619509590, 619506498, 619505529, 618635259, 601122424, 568760862, 564558494, 564476637, 554454052, 554069947, 554024905, 554022505, 549624647, 549616790, 549614805, 529291169, 528176141, 523809787, 482543506, 459466912, 459466694, 444836097, 444830410, 444805827, 444798239, 414061040, 414055287, 414046280, 414041703, 414041011, 414030220, 414027585, 414026997, 414013043, 414013009, 414011566, 392835621, 392829933, 392829647, 392824779, 392820914, 392807284, 392767436, 392761246, 392759260, 380465572, 323132500, 321223364, 194401008, 16422722, 6960363, 814255305, 814004308, 813965841, 807061567, 806894655, 805266378, 805261462, 805254561, 805249819, 805242906, 805226429, 805218938, 805203524, 802914743, 802473382, 802433736, 802424998, 802385417, 800346709, 800337773, 800194991, 777180962, 661250264, 548936988, 545010527, 312915270, 301160660, 261249268, 238693580, 18203231 KMM48012.1, KMJ76973.1, KMJ76646.1, KMJ72732.1, KMJ64836.1, KMJ62853.1, KMJ60901.1, KMJ37048.1, KMJ32781.1, KMJ28842.1, KMJ21907.1, KMJ19615.1, KMJ18496.1, KLT35158.1, KLT26705.1, KLT25418.1, KLT24259.1, KLT11531.1, AKH09764.1, KKE23850.1, KKD92840.1, KKD77492.1, AKD20055.1, AKD06212.1, AJB24285.1, AJB19995.1, AJB15059.1, AJB06566.1, AJA98842.1, AJQ76554.1, AJB10817.1, KHD79581.1, AIT50836.1, AIT45666.1, AIL22655.1, KAK18720.1, KAK16422.1, KAK06701.1, KAK03664.1, KAK02724.1, AHX79852.1, EYR75057.1, AHE23992.1, ETC54766.1, ETB74907.1, ESJ75217.1, ESF13940.1, ESE71217.1, ESE68935.1, ERO28193.1, ERO20779.1, ERO18817.1, EQA21733.1, AGS31503.1, AGQ69515.1, AGK11775.1, EMG61591.1, EMG61381.1, ELX63270.1, ELX57657.1, ELX33569.1, ELX26095.1, EKT42497.1, EKT37201.1, EKT28622.1, EKT24262.1, EKT23601.1, EKT13347.1, EKT10809.1, EKT10250.1, EKS96944.1, EKS96911.1, EKS95517.1, EJA91213.1, EJA85592.1, EJA85315.1, EJA80546.1, EJA76749.1, EJA63361.1, EJA24203.1, EJA18073.1, EJA16114.1, AFD60975.1, ADX19930.1, EFX48431.1, ACF61230.1, AAL22992.1, AAF33523.1 NP_463033.1, WP_000108413.1 B4T0Z6, Q9L9I7 THIC_SALNS, THIC_SALTY Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089}, Phosphomethylpyrimidine synthase 4413119, 151414, 7244407 fig|28901.42.peg.5121, fig|859197.3.peg.4921, fig|216597.6.peg.4566, fig|796730.3.peg.4861, fig|99287.1.peg.4006, fig|1171376.3.peg.4417, fig|909946.3.peg.4420, fig|858307.3.peg.1634, fig|858311.3.peg.2153, fig|1218152.3.peg.4292, fig|858310.3.peg.1992, fig|1218151.3.peg.4259, fig|796733.3.peg.2213, fig|1275975.3.peg.4697, fig|1218148.3.peg.4278, fig|796736.3.peg.1121, fig|858312.3.peg.151, fig|1218150.3.peg.4177, fig|858306.3.peg.215, fig|1218149.3.peg.4039, fig|1275977.3.peg.4685, fig|423368.6.peg.4496, fig|858305.3.peg.4449, fig|859196.3.peg.3611, fig|568708.3.peg.4394, fig|858309.3.peg.4755, fig|1218143.3.peg.4229, fig|796731.3.peg.4219, fig|1141101.3.peg.4253, fig|1218153.3.peg.4195, fig|1218146.3.peg.4211, fig|1218144.3.peg.4278, fig|1218147.3.peg.4246, fig|858308.3.peg.452, fig|796735.3.peg.4527, fig|718274.8.peg.4466, fig|796732.3.peg.1803, fig|946034.3.peg.3684, fig|1218145.3.peg.4149, fig|796737.3.peg.3051 626 631 yes 438026 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 272131, 63737 Nostoc punctiforme, Nostoc punctiforme PCC 73102 Bacteria UP000001191 501378495, 186466289, 238689251 ACC82090.1 WP_012410061.1 B2J323 THIC_NOSP7 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6875197 fig|63737.11.peg.4347, fig|63737.4.peg.3853 455 457 yes 438027 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 1454620, 1127355, 1127354, 1127353, 796734, 789645, 789647, 789642, 789646, 789643, 789644, 930778, 930779, 454168 Salmonella enterica, Salmonella enterica subsp. enterica serovar Newport str. USDA-ARS-USMARC-1927, Salmonella enterica subsp. enterica serovar Newport str. #11-2, Salmonella enterica subsp. enterica serovar Newport str. #11-3, Salmonella enterica subsp. enterica serovar Newport str. #11-4, Salmonella enterica subsp. enterica serovar Newport str. CVM 35202, Salmonella enterica subsp. enterica serovar Newport str. CVM 33953, Salmonella enterica subsp. enterica serovar Newport str. CVM 21559, Salmonella enterica subsp. enterica serovar Newport str. CVM 35185, Salmonella enterica subsp. enterica serovar Newport str. CVM 35188, Salmonella enterica subsp. enterica serovar Newport str. CVM 35199, Salmonella enterica subsp. enterica serovar Newport str. CVM 21539, Salmonella enterica subsp. enterica serovar Newport str. Levine 1, Salmonella enterica subsp. enterica serovar Newport str. Levine 15, Salmonella enterica subsp. enterica serovar Newport str. SL317 Bacteria UP000054489, UP000032219, UP000017091, UP000017165, UP000017167, UP000004623, UP000003433, UP000004094, UP000003897, UP000005719, UP000005319, UP000005292, UP000006768, UP000006747, UP000005552 446030573, 764048827, 549611096, 549602920, 549599457, 392778553, 392753231, 392748728, 392745020, 392744348, 392743201, 392739979, 392614906, 392612602, 195629019 AJQ67600.1, ERO15266.1, ERO07251.1, ERO03866.1, EJA35229.1, EJA10168.1, EJA05712.1, EJA02056.1, EJA01402.1, EJA00276.1, EIZ97106.1, EIW97347.1, EIW95072.1, EDX48411.1 WP_000108428.1 fig|789646.3.peg.4459, fig|789645.3.peg.172, fig|789642.3.peg.124, fig|454168.5.peg.4709, fig|930779.3.peg.4673, fig|789644.3.peg.481, fig|789647.3.peg.3895, fig|789643.3.peg.107, fig|796734.3.peg.1820, fig|930778.3.peg.3570 626 631 yes 438028 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 169435, 445972 Anaerotruncus colihominis, Anaerotruncus colihominis DSM 17241 Bacteria UP000003803 493929135, 167668688 EDS12818.1 WP_006873780.1 fig|445972.6.peg.709 434 434 yes 438029 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1502, 445334 Clostridium perfringens, Clostridium perfringens C str. JGS1495 Bacteria UP000059070, UP000003228 489548388, 169297392 EDS79501.1 WP_003453028.1 fig|445334.5.peg.2455 436 436 yes 438030 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1763, 36809, 319705, 1299325, 1353275, 1158135, 1149134, 1091046, 561007 Mycobacterium abscessus, Mycobacterium bolletii, Mycobacterium abscessus 103, Mycobacterium abscessus V06705, Mycobacterium abscessus M94, Mycobacterium abscessus M93, Mycobacterium abscessus subsp. bolletii BD, Mycobacterium abscessus ATCC 19977 Bacteria UP000046141, UP000030074, UP000029491, UP000015801, UP000005345, UP000004378, UP000005975, UP000007137 491219734, 169631274, 701178205, 690346160, 690340064, 528870348, 382947097, 382937726, 363996276, 238688919, 169243241 AIV12844.1, AIR40231.1, AIR35353.1, EPZ21638.1, EIC71378.1, EIC62071.1, EHM17493.1 WP_005078051.1, YP_001704923.1 B1MIP8 THIC_MYCA9 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3347353 fig|1001720.3.peg.4408, fig|1001725.3.peg.4020, fig|1001716.3.peg.4270, fig|1001723.3.peg.4020, fig|1001737.3.peg.4458, fig|1001722.3.peg.4012, fig|1246644.3.peg.85, fig|36809.5.peg.4274, fig|1001719.3.peg.4334, fig|1176125.3.peg.2236, fig|1001727.3.peg.3558, fig|1162284.3.peg.1886, fig|1001724.3.peg.3112, fig|1001726.3.peg.3947, fig|1091046.3.peg.4123, fig|1149134.5.peg.4675, fig|1001740.3.peg.3290, fig|1001736.3.peg.4257, fig|1175632.3.peg.4285, fig|1001715.3.peg.4493, fig|1001738.3.peg.4465, fig|1001718.3.peg.4535, fig|1158135.4.peg.233, fig|1001721.3.peg.4457, fig|1001739.3.peg.4277, fig|1001741.3.peg.4518, fig|1001717.3.peg.4460 545 546 yes 438031 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 59201, 1194154, 1173817, 1124980, 1173938, 454165, 439843 Salmonella enterica, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Bredeney str. CFSAN001080, Salmonella enterica subsp. enterica serovar Enteritidis str. 3402, Salmonella enterica subsp. enterica serovar Give str. 564, Salmonella enterica subsp. enterica serovar Urbana str. ATCC 9261, Salmonella enterica subsp. enterica serovar Schwarzengrund str. SL480, Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633 Bacteria UP000054489, UP000033855, UP000017423, UP000018573, UP000017545, UP000017384, UP000004551, UP000001865 446030561, 808751357, 605540603, 564566624, 554272778, 554073856, 197287731, 194710083, 238693655 KKE86017.1, AHW24465.1, ETC62769.1, ESH08725.1, ESF17698.1, EDY27122.1, ACF89304.1 WP_000108416.1 B4TQK4 THIC_SALSV Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7294484, 4786367 fig|454165.5.peg.4533, fig|439843.6.peg.4316 626 631 yes 438032 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 407, 426117 Methylobacterium sp. 4-46 Bacteria UP000001185 501290669, 168195665 ACA17612.1 WP_012333012.1 fig|426117.3.peg.2834, fig|398261.3.peg.1712 619 627 yes 438033 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1502, 488537 Clostridium perfringens, Clostridium perfringens D str. JGS1721 Bacteria UP000059070, UP000003188 490595040, 177910776 EDT73136.1 WP_004460060.1 fig|488537.5.peg.244 436 436 yes 438034 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1754, 509193, 340099 Thermoanaerobacter brockii subsp. finnii Ako-1, Thermoanaerobacter pseudethanolicus ATCC 33223 Bacteria UP000002062, UP000002156 501226014, 319928432, 166855756, 238687721 ADV79117.1, ABY94164.1 WP_012269032.1 B0KD66 THIC_THEP3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6947235 fig|340099.4.peg.491, fig|509193.3.peg.1577 431 432 yes 438035 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 1227358, 1053205, 718224, 526990, 315730 Bacillus weihenstephanensis FSL H7-687, Bacillus cereus HuA3-9, Bacillus cereus VD142, Bacillus cereus AH603, Bacillus weihenstephanensis KBAB4 Bacteria UP000019054, UP000014003, UP000006969, UP000001753, UP000002154 487996339, 573573251, 500290386, 401078320, 228716430, 163865105, 229558529 ETT71744.1, EOO14504.1, EJP86635.1, EEL68136.1, ABY46164.1 WP_002068339.1 A9VR68 THIC_BACWK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6904173 fig|315730.11.peg.5678, fig|526990.3.peg.1334, fig|1053205.3.peg.4300, fig|718224.3.peg.4393 586 586 yes 438036 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 223967, 441620 Methylobacterium populi, Methylobacterium populi BJ001 Bacteria UP000007136 501428870, 179344381 ACB79793.1 WP_012453540.1 fig|441620.7.peg.1664 623 630 yes 438037 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 90371, 440524, 149539, 891423, 891422, 891421, 1262136, 866913, 891424, 990282, 588858, 440534 Salmonella enterica, Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar 4,[5],12:i:-, Salmonella enterica subsp. enterica serovar Enteritidis, Salmonella enterica subsp. enterica serovar Typhimurium str. CDC_2009K1277, Salmonella enterica subsp. enterica serovar Typhimurium str. CDC_2009K1283, Salmonella enterica subsp. enterica serovar Typhimurium str. CDC_2009K1158, Salmonella enterica subsp. enterica serovar Typhimurium str. CDC_2009K1288, Salmonella enterica subsp. enterica serovar 4,[5],12:i:- str. 08-1736, Salmonella enterica subsp. enterica serovar Typhimurium str. CDC_2009K1153, Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1, Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S, Salmonella enterica subsp. enterica serovar 4,[5],12:i:- str. CVM23701 Bacteria UP000054489, UP000028938, UP000034812, UP000034332, UP000017158, UP000017140, UP000017145, UP000017156, UP000014927, UP000028387, UP000008278, UP000002695, UP000005987 446030556, 808329813, 808325226, 808319874, 808316948, 808308450, 808297374, 808289232, 808263035, 660593061, 549596600, 549587845, 549580667, 549578167, 523821091, 444819539, 332990983, 267996465, 205327259 KKE73449.1, KKE69155.1, KKE64030.1, KKE61187.1, KKE52837.1, KKE41974.1, KKE34075.1, KKE08508.1, AIE08124.1, ERO01071.1, ERN92469.1, ERN85401.1, ERN82937.1, AGQ83935.1, ELX46998.1, AEF09966.1, ACY91350.1, EDZ14023.1 WP_000108411.1 fig|440534.5.peg.4596, fig|588858.6.peg.4534, fig|990282.4.peg.4329 626 631 yes 438038 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 225849 Shewanella piezotolerans WP3 Bacteria UP000000753 212556621 ACJ29075.1 fig|225849.3.peg.2152 659 698 yes 438039 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 274539, 517417 Chlorobaculum parvum, Chlorobaculum parvum NCIB 8327 Bacteria UP000008811 501494396, 193086662, 238692651 ACF11938.1 WP_012502771.1 B3QPT5 THIC_CHLP8 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5763181 fig|517417.4.peg.1526 552 555 yes 438040 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 391600 Brevundimonas sp. BAL3 Bacteria UP000003957 196184593 EDX79569.1 fig|391600.3.peg.3438 434 435 yes 438041 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 251701, 323, 546231 Pseudomonas syringae group genomosp. 3, Pseudomonas syringae pv. tomato, Pseudomonas syringae pv. tomato T1 Bacteria UP000030934, UP000004139 494454311, 695907246, 213927236 KGK97559.1, EEB60785.1 WP_007244592.1 fig|673189.4.peg.3924, fig|673198.4.peg.3432, fig|673265.4.peg.2536, fig|546231.4.peg.1342 628 629 yes 438042 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 305, 342110, 564066 Ralstonia solanacearum, Ralstonia solanacearum UW551, Ralstonia solanacearum IPO1609 Bacteria UP000029286, UP000005933, UP000053470 489354456, 684087971, 682150269, 682145490, 679697723, 658126240, 83727389, 726236735 KFZ93612.1, KFX83672.1, KFX80134.1, KFX28970.1, KEI34243.1, EAP74511.1 WP_003261498.1 fig|342110.4.peg.504 629 631 yes 438043 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 1124917, 59201, 1406860, 1072587, 1072588, 1072589, 1072590, 1072591, 1072592, 1072593, 1072594, 935702, 1124923, 1124921, 1003187, 1003186, 1029990, 1003185, 1029989, 702984, 935703, 1003188, 1003189, 1124906, 1124907, 1124909, 1124908, 1124910, 1124913, 1124912, 1124911, 1124914, 1124915, 1124916, 1124918, 1124920, 1262654, 1263410, 1262652, 454166, 1265654, 1265658, 1265643, 1265612, 1265638, 1265659, 1265680, 1265613, 1265644, 1265668, 1265614, 1265650, 1265618, 1265639, 1265660, 1265645, 1265615, 1265640, 1265682, 1265646, 1265616, 1265641, 1265669, 1265617, 1265651, 1265621, 1265652, 1265622, 1265648, 1265670, 1265624, 1265653, 1265649, 1265681, 1265661, 1265647, 1265625, 1265667, 1265679, 1265673, 1265665, 1265636, 1265657, 1265678, 1265642, 1265611, 1265637, 1265623, 1265675, 1265662, 1265628, 1265655, 1265676, 1265626, 1265663, 1265629, 1265677, 1265631, 1265664, 1265630, 1265666, 1265619, 1265632, 1265671, 1265634, 1265620, 1265633, 1265672, 1265635, 1265674, 1265627 Salmonella enterica, Salmonella enterica subsp. enterica serovar Agona str. 460004 2-1, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Agona str. 24249, Salmonella enterica subsp. enterica serovar Agona str. 241981, Salmonella enterica subsp. enterica serovar Agona str. 246555-3, Salmonella enterica subsp. enterica serovar Agona str. 392869-1, Salmonella enterica subsp. enterica serovar Agona str. 392869-2, Salmonella enterica subsp. enterica serovar Agona str. 400095 11, Salmonella enterica subsp. enterica serovar Agona str. 400095 13, Salmonella enterica subsp. enterica serovar Agona str. 400095 14, Salmonella enterica subsp. enterica serovar Agona str. 400095 17, Salmonella enterica subsp. enterica serovar Agona str. ATCC 51957, Salmonella enterica subsp. enterica serovar Agona str. 648586-1, Salmonella enterica subsp. enterica serovar Agona str. 419639 2-1, Salmonella enterica subsp. enterica serovar Agona str. SA-3, Salmonella enterica subsp. enterica serovar Agona str. SA-2, Salmonella enterica subsp. enterica serovar Agona str. 0322, Salmonella enterica subsp. enterica serovar Agona str. SA-1, Salmonella enterica subsp. enterica serovar Agona str. 0292, Salmonella enterica subsp. enterica serovar Paratyphi B str. SARA61, Salmonella enterica subsp. enterica serovar Agona str. ATCC BAA-707, Salmonella enterica subsp. enterica serovar Agona str. SA-4, Salmonella enterica subsp. enterica serovar Agona str. SA-5, Salmonella enterica subsp. enterica serovar Agona str. 266757-1, Salmonella enterica subsp. enterica serovar Agona str. 432613, Salmonella enterica subsp. enterica serovar Agona str. 557928, Salmonella enterica subsp. enterica serovar Agona str. 467481, Salmonella enterica subsp. enterica serovar Agona str. 620239, Salmonella enterica subsp. enterica serovar Agona str. 442692 2-5, Salmonella enterica subsp. enterica serovar Agona str. 442692 2-4, Salmonella enterica subsp. enterica serovar Agona str. 409753-6, Salmonella enterica subsp. enterica serovar Agona str. 447967 1-1, Salmonella enterica subsp. enterica serovar Agona str. 447967 2-1, Salmonella enterica subsp. enterica serovar Agona str. 460004 1-1, Salmonella enterica subsp. enterica serovar Agona str. 339787, Salmonella enterica subsp. enterica serovar Agona str. 311387-1, Salmonella enterica subsp. enterica serovar Agona str. SH10GFN094, Salmonella enterica subsp. enterica serovar Agona str. SH11G1113, Salmonella enterica subsp. enterica serovar Agona str. SH08SF124, Salmonella enterica subsp. enterica serovar Agona str. SL483, Salmonella enterica subsp. enterica serovar Agona str. 47.E.09, Salmonella enterica subsp. enterica serovar Agona str. 09.F.08, Salmonella enterica subsp. enterica serovar Agona str. 11.A.05, Salmonella enterica subsp. enterica serovar Agona str. 12.A.06, Salmonella enterica subsp. enterica serovar Agona str. 13.E.05, Salmonella enterica subsp. enterica serovar Agona str. 14.E.05, Salmonella enterica subsp. enterica serovar Agona str. 15.H.03, Salmonella enterica subsp. enterica serovar Agona str. 17.H.06, Salmonella enterica subsp. enterica serovar Agona str. 18.H.07, Salmonella enterica subsp. enterica serovar Agona str. 19.F.03, Salmonella enterica subsp. enterica serovar Agona str. 20.H.06, Salmonella enterica subsp. enterica serovar Agona str. 21.H.10, Salmonella enterica subsp. enterica serovar Agona str. 22.H.04, Salmonella enterica subsp. enterica serovar Agona str. 23.F.01, Salmonella enterica subsp. enterica serovar Agona str. 24.H.04, Salmonella enterica subsp. enterica serovar Agona str. 27.O.98, Salmonella enterica subsp. enterica serovar Agona str. 28.O.08, Salmonella enterica subsp. enterica serovar Agona str. 29.O.08, Salmonella enterica subsp. enterica serovar Agona str. 31.H.09, Salmonella enterica subsp. enterica serovar Agona str. 32.A.00, Salmonella enterica subsp. enterica serovar Agona str. 33.A.05, Salmonella enterica subsp. enterica serovar Agona str. 34.H.09, Salmonella enterica subsp. enterica serovar Agona str. 35.H.08, Salmonella enterica subsp. enterica serovar Agona str. 36.H.00, Salmonella enterica subsp. enterica serovar Agona str. 37.F.02, Salmonella enterica subsp. enterica serovar Agona str. 38.O.03, Salmonella enterica subsp. enterica serovar Agona str. 41.E.09, Salmonella enterica subsp. enterica serovar Agona str. 40.E.08, Salmonella enterica subsp. enterica serovar Agona str. 42.E.09, Salmonella enterica subsp. enterica serovar Agona str. 43.E.09, Salmonella enterica subsp. enterica serovar Agona str. 44.E.09, Salmonella enterica subsp. enterica serovar Agona str. 45.E.09, Salmonella enterica subsp. enterica serovar Agona str. 16.H.08, Salmonella enterica subsp. enterica serovar Agona str. 26.F.98, Salmonella enterica subsp. enterica serovar Agona str. 30.H.04, Salmonella enterica subsp. enterica serovar Agona str. 39.O.03, Salmonella enterica subsp. enterica serovar Agona str. 49.E.09, Salmonella enterica subsp. enterica serovar Agona str. 67.H.09, Salmonella enterica subsp. enterica serovar Agona str. 10.A.05, Salmonella enterica subsp. enterica serovar Agona str. 01.O.05, Salmonella enterica subsp. enterica serovar Agona str. 02.O.05, Salmonella enterica subsp. enterica serovar Agona str. 03.O.05, Salmonella enterica subsp. enterica serovar Agona str. 04.O.05, Salmonella enterica subsp. enterica serovar Agona str. 05.O.06, Salmonella enterica subsp. enterica serovar Agona str. 06.O.05, Salmonella enterica subsp. enterica serovar Agona str. 07.O.05, Salmonella enterica subsp. enterica serovar Agona str. 08.A.05, Salmonella enterica subsp. enterica serovar Agona str. 46.E.09, Salmonella enterica subsp. enterica serovar Agona str. 48.E.08, Salmonella enterica subsp. enterica serovar Agona str. 50.E.08, Salmonella enterica subsp. enterica serovar Agona str. 51.E.09, Salmonella enterica subsp. enterica serovar Agona str. 52.F.08, Salmonella enterica subsp. enterica serovar Agona str. 53.F.08, Salmonella enterica subsp. enterica serovar Agona str. 54.O.08, Salmonella enterica subsp. enterica serovar Agona str. 55.U.08, Salmonella enterica subsp. enterica serovar Agona str. 56.O.08, Salmonella enterica subsp. enterica serovar Agona str. 58.E.08, Salmonella enterica subsp. enterica serovar Agona str. 59.F.08, Salmonella enterica subsp. enterica serovar Agona str. 60.O.08, Salmonella enterica subsp. enterica serovar Agona str. 61.O.08, Salmonella enterica subsp. enterica serovar Agona str. 62.H.72, Salmonella enterica subsp. enterica serovar Agona str. 63.H.87, Salmonella enterica subsp. enterica serovar Agona str. 64.H.00, Salmonella enterica subsp. enterica serovar Agona str. 65.H.72, Salmonella enterica subsp. enterica serovar Agona str. 66.F.99, Salmonella enterica subsp. enterica serovar Agona str. 68.U.05, Salmonella enterica subsp. enterica serovar Agona str. 69.H.06, Salmonella enterica subsp. enterica serovar Agona str. 70.E.05, Salmonella enterica subsp. enterica serovar Agona str. 71.E.05, Salmonella enterica subsp. enterica serovar Agona str. 72.A.52, Salmonella enterica subsp. enterica serovar Agona str. 73.H.09 Bacteria UP000054489, UP000017451, UP000033855, UP000018582, UP000017466, UP000017524, UP000017261, UP000017607, UP000017557, UP000017503, UP000017430, UP000017578, UP000017535, UP000017284, UP000017448, UP000017476, UP000017628, UP000017495, UP000017615, UP000017335, UP000017614, UP000017554, UP000017285, UP000017393, UP000017606, UP000017270, UP000017352, UP000017512, UP000017540, UP000017453, UP000017510, UP000017498, UP000017426, UP000017490, UP000017471, UP000017364, UP000017315, UP000010983, UP000010938, UP000010981, UP000008819, UP000018134, UP000013436, UP000013444, UP000013437, UP000013442, UP000013406, UP000013410, UP000013418, UP000013417, UP000013454, UP000013440, UP000013449, UP000013455, UP000013401, UP000013414, UP000013441, UP000013421, UP000013405, UP000013443, UP000013452, UP000013430, UP000013419, UP000013416, UP000013432, UP000013445, UP000013438, UP000013400, UP000013408, UP000013448, UP000013450, UP000013403, UP000013424, UP000018214, UP000013429, UP000013415, UP000013425, UP000013427, UP000013492, UP000013407, UP000013412, UP000013423, UP000013439, UP000013404, UP000013402, UP000013422, UP000013428, UP000013426, UP000013435, UP000013431, UP000013409, UP000013451, UP000013420, UP000013413, UP000013446, UP000013434, UP000013411, UP000013433, UP000013483, UP000013495, UP000013486, UP000013497, UP000013482, UP000013493, UP000013484, UP000013490, UP000013489, UP000013485, UP000013494, UP000013481, UP000013491, UP000013488 446030572, 807110412, 735793014, 735786895, 735779428, 735777998, 735771483, 735763238, 563350294, 555745233, 555741935, 555735094, 555730261, 555729386, 555723996, 555713842, 555713665, 554353915, 554345820, 554344507, 553521637, 553507436, 553504429, 553502813, 553500694, 553481402, 553462131, 553461870, 553453603, 553440706, 553438781, 553429229, 553428655, 553422068, 553418062, 553407885, 553407225, 553403110, 553399126, 553394478, 553385609, 553379664, 436422789, 436422571, 436411817, 197214294, 548924396, 485264103, 485259230, 485254283, 485249330, 485244470, 485239444, 485234489, 485229611, 485223793, 485211658, 485206587, 485201409, 485196629, 485191522, 485185884, 485180611, 485175828, 485170588, 485165665, 485160943, 485156072, 485151283, 485146432, 485138925, 485134604, 485125903, 485120167, 485115362, 485110457, 485106314, 485100754, 485027826, 485023274, 485017639, 485013338, 485007979, 484997932, 484992886, 484987750, 484982994, 484975579, 484970726, 484965046, 484959922, 484954077, 484949057, 484943927, 484938422, 484933566, 484928150, 484922743, 484917840, 484912982, 484908107, 484901597, 484842978, 484837989, 484833163, 484828603, 484824387, 484820012, 484794369, 484777513, 484762978, 484740744, 484394535, 484389756, 484384920, 484380636, 484372338, 238690024 AKC51020.1, KHP62873.1, KHP56818.1, KHP49447.1, KHP48028.1, KHP41600.1, KHP33432.1, AHB46643.1, ESO46759.1, ESO43523.1, ESO36791.1, ESO32035.1, ESO31171.1, ESO25882.1, ESO15906.1, ESO15736.1, ESH91275.1, ESH83447.1, ESH82179.1, ESC44706.1, ESC30783.1, ESC27841.1, ESC26270.1, ESC24219.1, ESC05516.1, ESB86738.1, ESB86484.1, ESB78389.1, ESB65741.1, ESB63862.1, ESB54508.1, ESB53949.1, ESB47464.1, ESB43541.1, ESB33519.1, ESB32873.1, ESB28814.1, ESB24890.1, ESB20307.1, ESB11583.1, ESB05716.1, ELP20616.1, ELP20404.1, ELP09764.1, ACH51691.1 WP_000108427.1 B5F1H7 THIC_SALA4 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7360291 fig|1265612.3.peg.4686, fig|1265647.3.peg.4481, fig|1265630.3.peg.4258, fig|1265626.3.peg.4685, fig|1265613.3.peg.4781, fig|1265627.3.peg.4601, fig|1265671.3.peg.4563, fig|1265670.3.peg.4722, fig|1265614.3.peg.4818, fig|1265652.3.peg.4040, fig|1265638.3.peg.4734, fig|1265618.3.peg.4716, fig|1265641.3.peg.4741, fig|1265674.3.peg.4061, fig|1265663.3.peg.4688, fig|1265669.3.peg.4746, fig|1265635.3.peg.4656, fig|1265675.3.peg.4719, fig|1265678.3.peg.4768, fig|1265639.3.peg.4629, fig|1265645.3.peg.4702, fig|1265653.3.peg.4664, fig|1265680.3.peg.4728, fig|1265661.3.peg.4854, fig|1265625.3.peg.4723, fig|1265655.3.peg.4683, fig|1265628.3.peg.4499, fig|1265616.3.peg.4626, fig|1265631.3.peg.4682, fig|1265659.3.peg.4691, fig|1265636.3.peg.4875, fig|1265643.3.peg.4671, fig|1265615.3.peg.4699, fig|1265665.3.peg.4534, fig|1263410.4.peg.1429, fig|1265651.3.peg.4647, fig|1265681.3.peg.4122, fig|1265620.3.peg.4713, fig|1265657.3.peg.4606, fig|1265640.3.peg.4513, fig|1265650.3.peg.4714, fig|1265677.3.peg.4670, fig|1265682.3.peg.4661, fig|1265632.3.peg.4746, fig|1265624.3.peg.4099, fig|1265622.3.peg.4817, fig|1265666.3.peg.3379, fig|1265664.3.peg.4648, fig|1265660.3.peg.4759, fig|1265621.3.peg.4267, fig|1265611.3.peg.4882, fig|1265633.3.peg.4816, fig|454166.6.peg.4268, fig|1265676.3.peg.4675, fig|1265623.3.peg.4720, fig|1265646.3.peg.4820, fig|1265629.3.peg.4683, fig|1265634.3.peg.3914, fig|1265662.3.peg.4521, fig|1265617.3.peg.4770, fig|1265667.3.peg.4789, fig|1265642.3.peg.4819, fig|1262654.4.peg.399, fig|1265637.3.peg.4782, fig|1262652.4.peg.4551, fig|1265673.3.peg.4698, fig|1265648.3.peg.4676, fig|1265619.3.peg.2649, fig|1265679.3.peg.4673, fig|1265668.3.peg.4630, fig|1265644.3.peg.4716, fig|1265672.3.peg.4707 626 631 yes 438044 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 313985, 398767 Geobacter lovleyi, Geobacter lovleyi SZ Bacteria UP000002420 501448245, 189422979 ACD97376.1 WP_012471694.1 fig|398767.5.peg.3596 432 436 yes 438045 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 236097 Alcanivorax sp. DG881 Bacteria UP000003954 494253055, 196193201 EDX88160.1 WP_007148568.1 fig|236097.3.peg.2046 621 624 yes 438046 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 100716, 517418 Chloroherpeton thalassium, Chloroherpeton thalassium ATCC 35110 Bacteria UP000001208 501492496, 193089576 ACF14851.1 WP_012500933.1 fig|517418.3.peg.2802 617 621 yes 438047 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1408, 536229 Bacillus pumilus, Bacillus pumilus ATCC 7061 Bacteria UP000037521, UP000003728 489309284, 194011194 EDW20764.1 WP_003216710.1 fig|536229.4.peg.3124 586 586 yes 438048 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 405917 Bacillus cereus, Bacillus cereus W Bacteria UP000036076, UP000004145 487909387, 195994681 EDX58636.1 WP_001982853.1 fig|405917.4.peg.778 586 586 yes 438049 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 445975 Collinsella stercoris DSM 13279 Bacteria UP000003560 210159163 EEA90134.1 458 459 yes 438050 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 447217 Anaeromyxobacter sp. K Bacteria UP000001871 501518305, 196172470, 238689855 ACG73443.1 WP_012526242.1 B4UDM7 THIC_ANASK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7346584 fig|447217.4.peg.2237 456 463 yes 438051 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 491915 Anoxybacillus flavithermus WK1 Bacteria UP000000742 212560958 ACJ34013.1 fig|491915.4.peg.1699 565 569 yes 438052 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 34090, 324925 Pelodictyon phaeoclathratiforme, Pelodictyon phaeoclathratiforme BU-1 Bacteria UP000002724 501500263, 194309310, 238693367 ACF44010.1 WP_012508497.1 B4SBF6 THIC_PELPB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6929894 fig|324925.4.peg.1899 543 544 yes 438053 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 126385, 520999 Providencia alcalifaciens, Providencia alcalifaciens DSM 30120 Bacteria UP000003729 493707380, 212688327 EEB47855.1 WP_006657060.1 fig|520999.6.peg.72 623 655 yes 438054 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28111, 483216 Bacteroides eggerthii, Bacteroides eggerthii DSM 20697 Bacteria UP000004742 490418616, 217986728 EEC53061.1 WP_004290940.1 fig|483216.6.peg.2214 561 562 yes 438055 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28261, 289376 Thermodesulfovibrio yellowstonii DSM 11347 Bacteria UP000000718 UP000000718 501541657, 206891089, 206743027, 238065982 ACI22084.1 WP_012546777.1, YP_002248290.1 B5YJ75 THIC_THEYD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5460088 fig|289376.4.peg.440 426 426 yes 438056 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 91464 Synechococcus sp. PCC 7335 Bacteria UP000005766 196189268 EDX84232.1 fig|91464.3.peg.392 497 500 yes 438057 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 911092, 391606 Caldanaerobacter subterraneus, Carboxydibrachium pacificum DSM 12653 Bacteria UP000053343, UP000010146 497295878, 806646702 KKC29517.1 WP_009610095.1 fig|391606.3.peg.712 431 432 yes 438058 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 516466 Burkholderia sp. H160 Bacteria UP000004534 496198925, 209502908 EEA02911.1 WP_008918762.1 fig|516466.4.peg.1680 642 643 yes 438059 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 46228, 1073376, 471875 Ruminococcus lactaris, Ruminococcaceae bacterium CC59_002D, Ruminococcus lactaris ATCC 29176 Bacteria UP000018683, UP000003254 491805277, 564725276, 197299301 ETD25276.1, EDY33828.1 WP_005609829.1 fig|471875.6.peg.816 436 436 yes 438060 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 34018, 414684 Rhodospirillum centenum, Rhodospirillum centenum SW Bacteria UP000001591 501564623, 209960674 ACJ01311.1 WP_012569084.1 fig|414684.4.peg.3865 608 623 yes 438061 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 190192, 2320 Methanopyrus kandleri AV19, Methanopyrus kandleri Archaea UP000001826 20093546, 499327986, 19886390, 24638264 AAM01323.1 NP_613393.1, WP_011018478.1 Q8TZ33 THIC_METKA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 231744 fig|190192.1.peg.106 429 429 yes 438062 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 190485, 339, 314565, 509169, 340 Xanthomonas campestris pv. campestris str. ATCC 33913, Xanthomonas campestris, Xanthomonas campestris pv. campestris str. 8004, Xanthomonas campestris pv. campestris str. B100, Xanthomonas campestris pv. campestris Bacteria UP000001010 UP000001010, UP000037537, UP000000420, UP000001188, UP000050151 21232748, 499349125, 66572511, 21114564, 229558547, 167732034, 81306837, 24638247 AAY47921.1, AAM42589.1 NP_638665.1, WP_011038418.1 Q4UYF2, B0RP37, Q8P5L9 THIC_XANC8, THIC_XANCB, THIC_XANCP Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5745121, 948571, 254606 fig|509169.3.peg.901, fig|1182783.3.peg.1358, fig|1211707.3.peg.842, fig|314565.3.peg.351, fig|190485.1.peg.3270 623 625 yes 438063 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 191863, 497964 Chthoniobacter flavus, Chthoniobacter flavus Ellin428 Bacteria UP000005824 494038500, 196224613 EDY19124.1 WP_006980626.1 fig|497964.5.peg.3360 684 684 yes 438064 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1076, 395960 Rhodopseudomonas palustris, Rhodopseudomonas palustris TIE-1 Bacteria UP000032515, UP000001725 501488530, 192286211, 238692590 ACF02592.1 WP_012497004.1 B3QFS9 THIC_RHOPT Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7137661 fig|395960.3.peg.4133 631 641 yes 438065 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2261, 1185654, 186497 Pyrococcus furiosus, Pyrococcus furiosus COM1, Pyrococcus furiosus DSM 3638 Archaea UP000006216, UP000001013 499322186, 393189615, 18893667, 24638265 AFN04313.1, AAL81655.1 WP_011012678.1 Q8U0Q4, I6V2G2 THIC_PYRFU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} I6V2G2_9EURY 189236 fig|186497.1.peg.1578 429 429 yes 438066 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 379547, 439481 Aciduliprofundum boonei, Aciduliprofundum boonei T469 Archaea UP000001400 495357577, 289534249, 197624339 ADD08596.1, EDY36900.1 WP_008082298.1 B5I9D5 B5I9D5_ACIB4 425 425 yes 438067 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1176482, 929558 Sulfurimonas gotlandica, Sulfurimonas sp. GD1 Bacteria UP000004655 495613533, 372468869, 207085172 EHP29073.1, EDZ62458.1 WP_008338112.1 fig|929558.5.peg.544, fig|439483.4.peg.1578 463 465 yes 438068 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 40269, 316275 Aliivibrio salmonicida, Aliivibrio salmonicida LFI1238 Bacteria UP000001730 501546824, 238065978, 208010331 WP_012551384.1 B6EGV1 THIC_ALISL Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5494896 fig|316275.15.peg.3227 640 648 yes 438069 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 816, 483217 Bacteroides dorei DSM 17855 Bacteria UP000004849 495110213, 212664450 EEB25022.1 WP_007835034.1 566 566 yes 438070 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 40324, 522373 Stenotrophomonas maltophilia, Stenotrophomonas maltophilia K279a Bacteria UP000034806, UP000008840 501457750, 674294355, 229558546, 190013677 AIL09254.1 WP_012481195.1 B2FT70 THIC_STRMK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5779055 fig|522373.3.peg.3684, fig|40324.1.peg.1162 613 614 yes 438071 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 118168 Microcoleus chthonoplastes PCC 7420 Bacteria UP000003835 196182156 EDX77142.1 fig|118168.3.peg.1659 439 440 yes 438072 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 696867, 149539, 926034, 1412600, 886715, 1412549, 1412505, 1412479, 1412478, 1412480, 1412454, 1412455, 1412457, 1412470, 1243619, 1244122, 1244121, 1243618, 1243620, 1412453, 1412501, 1412562, 1412618, 1412471, 1244120, 1412465, 1412582, 1412583, 1412527, 1412526, 1412571, 1412542, 1412619, 1412558, 1412531, 1412617, 1412615, 1412614, 1412613, 1412532, 1412533, 1412612, 1412611, 1412564, 1412610, 1412609, 1412551, 1412540, 1412541, 1412560, 1412563, 1412599, 1412598, 1412585, 1412513, 1412464, 1412586, 1412606, 1412605, 1412604, 1412603, 1412504, 1412524, 1412510, 1412519, 1412511, 1412567, 1412538, 1412539, 1412456, 1412602, 1412546, 1412547, 1412548, 1412545, 1412568, 1412556, 1412552, 1412557, 1412554, 1412483, 1412616, 1412561, 1412565, 1412581, 1412550, 1412608, 1412607, 1412584, 1412476, 1412587, 1412579, 1412580, 1412555, 1412575, 1412576, 1412577, 1412578, 1412589, 1412495, 1412573, 1412574, 1412462, 1412463, 1412458, 1412529, 1412591, 1412469, 1412467, 1412466, 1412535, 1412572, 1412507, 1412503, 1412508, 1412594, 1412570, 1412518, 1412484, 1412515, 1412516, 1412491, 1412509, 1412520, 1412522, 1412512, 1412514, 1412523, 1412521, 1412461, 1412459, 1412460, 1412485, 1412472, 1412496, 1412474, 1412473, 1412497, 1412487, 1412494, 1412493, 1412500, 1412477, 1412490, 1412506, 1412452, 1412498, 1412502, 1412486, 1243621, 1244111, 1244112, 1244113, 1244118, 1244119, 1412566, 1412543, 1412536, 1412468, 1412451, 1412597, 1412596, 1412595, 1412593, 1412592, 1331043, 1410936, 1079470, 1079471, 1247529, 1225522, 1298917, 1192591, 1192592, 1192590, 1192588, 1192587, 1192589, 1192586, 1192585, 696869, 696868, 696866, 696870, 1116477, 1079475, 997329, 997328, 984233, 984234, 984232, 984231, 984229, 984226, 984225, 984224, 984223, 984221, 984222, 984220, 984219, 984218, 984217, 984214, 925130, 984216, 984215, 984213, 938147, 984212, 930768, 925133, 925132, 925131, 925129, 925127, 891414, 925126, 891412, 887070, 887067, 887069, 887068, 887063, 886728, 886720, 886725, 886726, 886727, 886723, 886724, 886722, 886718, 886721, 886719, 886717, 886716, 885385, 885387, 885386, 885384, 885383, 885382, 885381, 885380, 882879, 882878, 702978, 882877, 882876, 882875, 882874, 882873, 882872, 702979, 1029979, 984230, 1090945, 1116476, 984228, 926037, 930769, 926036, 926035, 910417, 910418, 910419, 910414, 910416, 910415, 891413, 891411, 910413, 887064, 887065, 887066, 1081093, 605, 550537 Salmonella enterica, Salmonella enterica subsp. enterica serovar Enteritidis str. 18569, Salmonella enterica subsp. enterica serovar Enteritidis, Salmonella enterica subsp. enterica serovar Enteritidis str. 77-1427, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20100325, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_0968, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20111510, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094301, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094177, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20084824, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20084644, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20090698, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110221, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20100101, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120008, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110354, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20111174, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20111175, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110353, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110355, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20090641, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19940857, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121747, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120929, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120009, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20111095, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20100134, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121970, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121969, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121826, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121825, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121812, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120970, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120969, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120968, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120963, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120927, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120925, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120918, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120917, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120776, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120775, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120774, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120773, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120765, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120738, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120734, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121753, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121751, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121750, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121748, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121746, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20100089, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20100088, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20090530, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20090435, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20100130, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20100100, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120597, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120590, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120581, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120580, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094350, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094079, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20093977, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20093950, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20093788, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20111554, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20111515, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20111514, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110222, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120356, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120240, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120229, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120219, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120498, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120497, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120496, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120469, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121542, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121744, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20121703, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121689, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121672, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121671, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121976, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120722, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120687, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120686, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20100131, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094682, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20090195, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121989, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121986, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121765, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20122031, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20122026, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20122022, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121990, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20130346, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20123395, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20122045, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20122033, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20090531, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20090884, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20100103, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120200, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20130348, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120007, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120003, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120002, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20111576, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20111561, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20095309, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094803, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20092320, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121177, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120916, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094642, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094521, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094389, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094383, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20094352, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20093784, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20093543, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20093538, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20093430, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20093421, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20091739, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20090877, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20090332, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20090193, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20090135, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19981522, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19980677, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19971331, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19970769, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19970510, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19961622, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19960848, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19943269, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19942384, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19930684, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20084384, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20083636, Salmonella enterica subsp. enterica serovar Enteritidis str. SA20083456, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19992322, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19983126, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19982831, Salmonella enterica subsp. enterica serovar Enteritidis str. SA19981857, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110356, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110357, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110358, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110359, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110360, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110361, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120555, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120548, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120544, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120005, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20110223, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121180, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121179, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121178, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121176, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121175, Salmonella enterica subsp. enterica serovar Gallinarum str. AB198, Salmonella enterica subsp. enterica serovar Montevideo str. CFSAN004346, Salmonella enterica subsp. enterica serovar Pullorum str. 19945, Salmonella enterica subsp. enterica serovar Pullorum str. 13036, Salmonella enterica subsp. enterica serovar Enteritidis str. 10-34587, Salmonella enterica subsp. enterica serovar Gallinarum/Pullorum str. CDC1983-67, Salmonella enterica subsp. enterica serovar Pullorum str. S06004, Salmonella enterica subsp. enterica serovar Enteritidis str. 2010K-0271, Salmonella enterica subsp. enterica serovar Enteritidis str. 2010K-0284, Salmonella enterica subsp. enterica serovar Enteritidis str. 2010K-0267, Salmonella enterica subsp. enterica serovar Enteritidis str. 2009K1726, Salmonella enterica subsp. enterica serovar Enteritidis str. 2009K1651, Salmonella enterica subsp. enterica serovar Enteritidis str. 2010K-0262, Salmonella enterica subsp. enterica serovar Enteritidis str. 2009K0958, Salmonella enterica subsp. enterica serovar Enteritidis str. 08-1080, Salmonella enterica subsp. enterica serovar Enteritidis str. 436, Salmonella enterica subsp. enterica serovar Enteritidis str. PT23, Salmonella enterica subsp. enterica serovar Enteritidis str. 13-1, Salmonella enterica subsp. enterica serovar Enteritidis str. SE8a, Salmonella enterica subsp. enterica serovar Enteritidis str. 53-407, Salmonella enterica subsp. enterica serovar Enteritidis str. 81-2625, Salmonella enterica subsp. enterica serovar Enteritidis str. 33944, Salmonella enterica subsp. enterica serovar Enteritidis str. 76-2651, Salmonella enterica subsp. enterica serovar Enteritidis str. 543463 42-20, Salmonella enterica subsp. enterica serovar Enteritidis str. 648901 16-16, Salmonella enterica subsp. enterica serovar Enteritidis str. 561362 9-7, Salmonella enterica subsp. enterica serovar Enteritidis str. 642044 8-1, Salmonella enterica subsp. enterica serovar Enteritidis str. 653049 13-19, Salmonella enterica subsp. enterica serovar Enteritidis str. 648903 1-6, Salmonella enterica subsp. enterica serovar Enteritidis str. 648902 6-8, Salmonella enterica subsp. enterica serovar Enteritidis str. 648901 39-2, Salmonella enterica subsp. enterica serovar Enteritidis str. 648901 1-17, Salmonella enterica subsp. enterica serovar Enteritidis str. 648899 3-17, Salmonella enterica subsp. enterica serovar Enteritidis str. 648900 1-16, Salmonella enterica subsp. enterica serovar Enteritidis str. 648898 4-5, Salmonella enterica subsp. enterica serovar Enteritidis str. 642046 4-7, Salmonella enterica subsp. enterica serovar Enteritidis str. 642044 4-1, Salmonella enterica subsp. enterica serovar Enteritidis str. 561362 1-1, Salmonella enterica subsp. enterica serovar Enteritidis str. 22558, Salmonella enterica subsp. enterica serovar Enteritidis str. 13183-1, Salmonella enterica subsp. enterica serovar Enteritidis str. 543463 40-18, Salmonella enterica subsp. enterica serovar Enteritidis str. 543463 22-17, Salmonella enterica subsp. enterica serovar Enteritidis str. CHS4, Salmonella enterica subsp. enterica serovar Enteritidis str. 638970-15, Salmonella enterica subsp. enterica serovar Enteritidis str. 17927, Salmonella enterica subsp. enterica serovar Enteritidis str. CVM_69-4941, Salmonella enterica subsp. enterica serovar Enteritidis str. SL913, Salmonella enterica subsp. enterica serovar Enteritidis str. SL909, Salmonella enterica subsp. enterica serovar Enteritidis str. CVM_81-2490, Salmonella enterica subsp. enterica serovar Enteritidis str. CVM_76-3618, Salmonella enterica subsp. enterica serovar Enteritidis str. CVM_N202, Salmonella enterica subsp. enterica serovar Enteritidis str. 629163, Salmonella enterica subsp. enterica serovar Enteritidis str. SE15-1, Salmonella enterica subsp. enterica serovar Enteritidis str. 607308-9, Salmonella enterica subsp. enterica serovar Enteritidis str. 607307-2, Salmonella enterica subsp. enterica serovar Enteritidis str. 635290-58, Salmonella enterica subsp. enterica serovar Enteritidis str. 607308-19, Salmonella enterica subsp. enterica serovar Enteritidis str. 607308-16, Salmonella enterica subsp. enterica serovar Enteritidis str. 576709, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1791, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1795, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1575, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1725, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1745, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_0956, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1455, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1811, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1559, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1808, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1565, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1445, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1444, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_0899, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1747, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1457, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_0895, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1729, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1010, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1018, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1558, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1810, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1441, Salmonella enterica subsp. enterica serovar Enteritidis str. SE30663, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1543, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1580, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1566, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1594, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1884, Salmonella enterica subsp. enterica serovar Enteritidis str. CDC_2010K_1882, Salmonella enterica subsp. enterica serovar Enteritidis str. CHS44, Salmonella enterica subsp. enterica serovar Pullorum str. ATCC 9120, Salmonella enterica subsp. enterica serovar Enteritidis str. 648901 6-18, Salmonella enterica subsp. enterica serovar Enteritidis str. 50-3079, Salmonella enterica subsp. enterica serovar Enteritidis str. 58-6482, Salmonella enterica subsp. enterica serovar Enteritidis str. 648905 5-18, Salmonella enterica subsp. enterica serovar Enteritidis str. 22510-1, Salmonella enterica subsp. enterica serovar Enteritidis str. 8b-1, Salmonella enterica subsp. enterica serovar Enteritidis str. 78-1757, Salmonella enterica subsp. enterica serovar Enteritidis str. 77-2659, Salmonella enterica subsp. enterica serovar Enteritidis str. 629164-37, Salmonella enterica subsp. enterica serovar Enteritidis str. 639672-46, Salmonella enterica subsp. enterica serovar Enteritidis str. 639672-50, Salmonella enterica subsp. enterica serovar Enteritidis str. 596866-22, Salmonella enterica subsp. enterica serovar Enteritidis str. 629164-26, Salmonella enterica subsp. enterica serovar Enteritidis str. 596866-70, Salmonella enterica subsp. enterica serovar Enteritidis str. 607307-6, Salmonella enterica subsp. enterica serovar Enteritidis str. 77-0424, Salmonella enterica subsp. enterica serovar Enteritidis str. 485549-17, Salmonella enterica subsp. enterica serovar Enteritidis str. 622731-39, Salmonella enterica subsp. enterica serovar Enteritidis str. 639016-6, Salmonella enterica subsp. enterica serovar Enteritidis str. 640631, Salmonella enterica subsp. enterica serovar Gallinarum/pullorum str. RKS5078, Salmonella enterica subsp. enterica serovar Pullorum, Salmonella enterica subsp. enterica serovar Enteritidis str. P125109 Bacteria UP000054489, UP000011540, UP000034332, UP000006500, UP000023672, UP000010942, UP000023706, UP000023650, UP000023602, UP000023722, UP000023734, UP000023716, UP000023597, UP000023647, UP000023584, UP000023593, UP000023693, UP000023662, UP000023689, UP000023626, UP000023721, UP000023752, UP000023641, UP000023738, UP000069077, UP000023740, UP000031763, UP000023742, UP000023657, UP000023764, UP000023705, UP000023694, UP000023692, UP000023704, UP000023681, UP000023612, UP000023700, UP000023610, UP000023768, UP000023746, UP000023690, UP000023634, UP000023671, UP000023743, UP000031747, UP000032840, UP000023580, UP000023729, UP000023639, UP000023697, UP000023679, UP000023624, UP000023656, UP000023646, UP000023618, UP000023715, UP000023701, UP000023685, UP000023590, UP000023750, UP000023616, UP000023754, UP000023595, UP000023631, UP000023667, UP000023761, UP000023691, UP000023769, UP000023666, UP000023655, UP000023668, UP000023607, UP000023587, UP000023683, UP000023728, UP000023630, UP000023636, UP000023673, UP000023617, UP000023665, UP000023714, UP000023621, UP000023737, UP000023637, UP000023724, UP000023731, UP000023745, UP000023586, UP000023651, UP000023605, UP000023717, UP000023733, UP000023599, UP000023725, UP000023723, UP000023603, UP000023596, UP000023625, UP000023760, UP000023664, UP000023713, UP000023711, UP000023609, UP000023680, UP000023708, UP000023770, UP000023652, UP000023601, UP000023675, UP000023619, UP000023614, UP000023702, UP000023663, UP000023739, UP000023589, UP000023635, UP000023726, UP000023643, UP000023654, UP000023649, UP000023638, UP000023687, UP000023744, UP000023653, UP000023677, UP000023613, UP000023660, UP000023766, UP000023585, UP000023581, UP000023588, UP000023598, UP000023686, UP000023600, UP000023629, UP000023628, UP000023720, UP000023765, UP000019803, UP000019153, UP000018536, UP000017403, UP000017629, UP000016530, UP000016224, UP000015424, UP000014528, UP000014555, UP000015845, UP000016525, UP000014611, UP000014615, UP000014535, UP000014619, UP000011506, UP000011502, UP000011510, UP000011604, UP000010973, UP000010968, UP000010954, UP000010926, UP000010945, UP000010896, UP000010937, UP000010929, UP000010962, UP000010975, UP000010892, UP000010949, UP000010919, UP000010890, UP000010961, UP000010934, UP000010895, UP000010902, UP000010920, UP000010972, UP000010897, UP000010915, UP000010898, UP000010921, UP000010894, UP000010964, UP000010905, UP000010948, UP000010918, UP000010922, UP000010906, UP000010980, UP000010978, UP000010951, UP000010955, UP000010941, UP000010946, UP000010958, UP000010911, UP000010924, UP000010903, UP000010947, UP000010982, UP000010899, UP000010927, UP000010979, UP000010909, UP000010925, UP000010908, UP000010939, UP000010971, UP000010966, UP000010891, UP000010916, UP000010907, UP000010933, UP000010969, UP000010984, UP000010944, UP000010960, UP000010923, UP000010974, UP000010917, UP000010950, UP000010930, UP000010928, UP000010914, UP000010943, UP000010940, UP000010935, UP000010965, UP000010967, UP000009028, UP000006473, UP000006479, UP000006496, UP000006481, UP000006478, UP000009020, UP000006477, UP000009033, UP000009032, UP000006474, UP000006492, UP000006494, UP000009025, UP000009037, UP000009035, UP000006482, UP000006488, UP000009029, UP000009019, UP000005873, UP000053887, UP000000613 446030574, 820762512, 808271069, 808226544, 721557122, 684204100, 682097485, 682093163, 682088789, 682084408, 682080041, 682075675, 682071311, 682066961, 682062683, 682053128, 682040445, 630834028, 610433063, 605555330, 605502008, 604424980, 604408460, 604398962, 604388169, 604375723, 604366011, 604354469, 604340462, 604326423, 604311108, 604294400, 604282505, 604272242, 604261885, 604247940, 604227654, 604210748, 604200291, 604196283, 604194235, 604175852, 604171578, 604167294, 604163004, 604158629, 604154350, 604150073, 604145742, 604141391, 604137116, 604132835, 604128635, 604124353, 604120092, 604115669, 604111387, 604107104, 604102819, 604098503, 604094223, 604089956, 604085693, 604081443, 604077173, 604072931, 604068693, 604063542, 604058546, 604054390, 604048207, 604041971, 604037653, 604030512, 604026235, 604021957, 604017595, 603855279, 603843355, 603828109, 603815123, 603802184, 603789350, 603775222, 603763829, 603752479, 603728292, 603712382, 603698057, 603680513, 603644041, 603632802, 603623811, 603613740, 603602875, 603559649, 603551988, 603545389, 603538942, 603530244, 603521140, 603510713, 603493296, 603481029, 603466883, 603459724, 603451176, 603427926, 603419763, 603412098, 603396835, 603389078, 603381245, 603372966, 603359532, 603341863, 603332030, 603322274, 603312164, 603303144, 603292741, 603281344, 603271503, 603246009, 603232489, 603218469, 603204619, 603188422, 603175728, 603162714, 603150904, 603138951, 603130969, 603123915, 603114715, 603101617, 603087524, 603075900, 603064603, 603053809, 603043700, 603033262, 603022950, 603011659, 603000802, 602989760, 602977867, 602963915, 602950683, 602937598, 602925190, 602912274, 602898646, 602884854, 602880219, 602875880, 602871607, 602867338, 602863028, 602858939, 602854638, 602847483, 602843155, 602838887, 602834613, 602830292, 602825962, 602821618, 602817287, 602812915, 602808589, 602804254, 602799972, 602795691, 602791259, 602786855, 602774229, 602769902, 602764992, 602758774, 602754504, 575531725, 564549888, 554166830, 553451716, 541921165, 537375534, 529192616, 514643027, 514641407, 514637828, 514631114, 514629124, 514622314, 514615165, 514610288, 444890948, 444883850, 444876187, 444860090, 435327542, 435320743, 435301287, 435296383, 435292865, 435292288, 435279844, 435271586, 435267415, 435264631, 435258078, 435248757, 435243991, 435242894, 435237565, 435228575, 435223147, 435215921, 435215205, 435214301, 435213317, 435206559, 435202855, 435194571, 435187576, 435187316, 435184887, 435177310, 435177040, 435166909, 435162754, 435150292, 435146681, 435145250, 435130479, 435129509, 435125706, 435120986, 435120637, 435118014, 435111529, 435106766, 435101471, 435099695, 435091572, 435080253, 435078279, 435077175, 435070327, 435067351, 435063110, 435058374, 435048976, 435042201, 435040295, 435037485, 435032754, 435025030, 435022625, 435020560, 435007748, 435006570, 434996798, 434994686, 434994631, 434988981, 434984827, 434977668, 434972492, 434970256, 434957723, 434943121, 396074913, 396073947, 396063434, 396062481, 396059763, 396050327, 396039108, 396035216, 396035173, 396034645, 396023719, 396022840, 396015704, 396012813, 396012023, 396007302, 396002029, 395996419, 395994187, 395988734, 395985264, 357207633, 661554236, 238690420, 206711145 AKG79320.1, KKE16434.1, KKD72673.1, KGZ00464.1, AIN66391.1, AIN12039.1, AIN07718.1, AIN03350.1, AIM98984.1, AIM94619.1, AIM90254.1, AIM85891.1, AIM81542.1, AIM77265.1, AIM72354.1, AIM68816.1, AHZ05021.1, AHT95486.1, AHW04064.1, AHW03585.1, AHV77345.1, AHV69249.1, AHV68645.1, AHV64857.1, AHV59959.1, AHV11970.1, AHV07637.1, AHV03292.1, AHU98961.1, AHU94619.1, AHV33272.1, AHV28942.1, AHV24638.1, AHV20678.1, AHV16344.1, AHV56087.1, AHV51908.1, AHV47712.1, AHV43735.1, AHV41692.1, AHT91087.1, AHU81203.1, AHU76920.1, AHU72631.1, AHU68375.1, AHU64097.1, AHU59821.1, AHU55491.1, AHU51407.1, AHU47133.1, AHU42853.1, AHU38656.1, AHU34375.1, AHU30115.1, AHU25843.1, AHU21562.1, AHT78176.1, AHT73892.1, AHT69612.1, AHT65333.1, AHT61067.1, AHT37011.1, AHT32762.1, AHT28493.1, AHT24252.1, AHT20015.1, AHU17269.1, AHU13031.1, AHU08876.1, AHU04680.1, AHT86715.1, AHT82444.1, AHT53946.1, AHT49670.1, AHT45393.1, AHT41033.1, AHQ97297.1, AHQ93018.1, AHQ88736.1, AHQ84454.1, AHQ80172.1, AHR63063.1, AHR58778.1, AHR54496.1, AHR50219.1, AHS03285.1, AHR99049.1, AHR94768.1, AHR90489.1, AHS20051.1, AHS16137.1, AHS11855.1, AHS07573.1, AHS58386.1, AHS96163.1, AHS91883.1, AHS87544.1, AHS83513.1, AHS79252.1, AHT15738.1, AHT11451.1, AHT04683.1, AHT00431.1, AHS72821.1, AHS68612.1, AHS64456.1, AHS38942.1, AHS34655.1, AHS30378.1, AHR82633.1, AHR78358.1, AHR74086.1, AHR69832.1, AHR43063.1, AHR34472.1, AHR30207.1, AHR25917.1, AHR21514.1, AHR17111.1, AHR12671.1, AHR08259.1, AHR04367.1, AHQ75826.1, AHQ71348.1, AHQ66927.1, AHQ62635.1, AHQ58353.1, AHQ54065.1, AHQ49802.1, AHQ44975.1, AHQ37627.1, AHQ34299.1, AHQ32034.1, AHQ27783.1, AHQ23525.1, AHQ19257.1, AHQ14979.1, AHQ10645.1, AHQ06369.1, AHQ02088.1, AHP97807.1, AHP93523.1, AHP89266.1, AHP84993.1, AHP80614.1, AHP76242.1, AHP71871.1, AHP47758.1, AHP43417.1, AHP39148.1, AHP34890.1, AHP30598.1, AHP26264.1, AHP21986.1, AHP17648.1, AHP13376.1, AHP67605.1, AHP63296.1, AHP59208.1, AHP54909.1, AHP09105.1, AHP04778.1, AHP00511.1, AHO96237.1, AHO91917.1, AHO70429.1, AHO66086.1, AHO61756.1, AHO57385.1, AHO53060.1, AHO48513.1, AHO44232.1, AHO39952.1, AHO35521.1, AHO31118.1, AHO18495.1, AHO14169.1, AHO09260.1, AHO03043.1, AHN98773.1, ETX32305.1, ETC46493.1, ESG06363.1, ESB76548.1, ERH37332.1, AGU66177.1, AGS64365.1, EPJ01463.1, EPJ00021.1, EPI96595.1, EPI90230.1, EPI88272.1, EPI81651.1, EPI74840.1, EPI70059.1, ELY14238.1, ELY07711.1, ELY00370.1, ELX85018.1, ELO99215.1, ELO93249.1, ELO77324.1, ELO72769.1, ELO69607.1, ELO69060.1, ELO57587.1, ELO50041.1, ELO46118.1, ELO43537.1, ELO37347.1, ELO28609.1, ELO24234.1, ELO23196.1, ELO18233.1, ELO10000.1, ELO05182.1, ELN98404.1, ELN97919.1, ELN97121.1, ELN96225.1, ELN90071.1, ELN86664.1, ELN79008.1, ELN72330.1, ELN72091.1, ELN69802.1, ELN62641.1, ELN62385.1, ELN52857.1, ELN48913.1, ELN36971.1, ELN33472.1, ELN32070.1, ELN17718.1, ELN16803.1, ELN13144.1, ELN08545.1, ELN08207.1, ELN05696.1, ELM99423.1, ELM94782.1, ELM89623.1, ELM87889.1, ELM79958.1, ELM68936.1, ELM67012.1, ELM65941.1, ELM59318.1, ELM56401.1, ELM52276.1, ELM47713.1, ELM38521.1, ELM31929.1, ELM30053.1, ELM27290.1, ELM22678.1, ELM15213.1, ELM12932.1, ELM10958.1, ELL98588.1, ELL97456.1, ELL88094.1, ELL86011.1, ELL85968.1, ELL80561.1, ELL76541.1, ELL69773.1, ELL64948.1, ELL62883.1, ELL51342.1, ELL49295.1, EJI83193.1, EJI82240.1, EJI71827.1, EJI70893.1, EJI68212.1, EJI58855.1, EJI47737.1, EJI43891.1, EJI43850.1, EJI43333.1, EJI32514.1, EJI31648.1, EJI24577.1, EJI21705.1, EJI20922.1, EJI16259.1, EJI11035.1, EJI05467.1, EJI03265.1, EJH97881.1, EJH94436.1, AET55679.1 WP_000108429.1 B5QYE9 THIC_SALEP Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5798755 fig|997328.3.peg.3872, fig|926036.3.peg.3313, fig|891414.3.peg.452, fig|984222.3.peg.3366, fig|696870.3.peg.3412, fig|1090945.3.peg.14, fig|885387.3.peg.3543, fig|882876.3.peg.3038, fig|696867.3.peg.3440, fig|925131.3.peg.486, fig|887070.3.peg.3990, fig|886722.3.peg.3278, fig|696866.4.peg.3062, fig|910417.3.peg.86, fig|926035.3.peg.4724, fig|984225.3.peg.2105, fig|891411.3.peg.1996, fig|1081093.3.peg.3493, fig|882872.3.peg.21, fig|886718.3.peg.806, fig|887069.3.peg.4006, fig|984231.3.peg.3721, fig|910413.3.peg.4092, fig|882878.3.peg.4096, fig|984216.3.peg.4727, fig|925132.3.peg.570, fig|886728.3.peg.21, fig|925129.3.peg.1783, fig|887065.3.peg.2081, fig|984224.3.peg.4724, fig|550537.3.peg.4207, fig|887064.3.peg.21, fig|926034.3.peg.4271, fig|984234.3.peg.1310, fig|887068.3.peg.3239, fig|886721.3.peg.3243, fig|925127.3.peg.2078, fig|885381.3.peg.158, fig|1182757.3.peg.4588, fig|886715.3.peg.4188, fig|886716.3.peg.3310, fig|1182761.3.peg.4683, fig|886717.3.peg.1766, fig|1182760.3.peg.4609, fig|984233.3.peg.838, fig|885380.3.peg.3381, fig|1079475.3.peg.169, fig|930768.3.peg.790, fig|910418.3.peg.4047, fig|882873.3.peg.3246, fig|887063.3.peg.91, fig|885382.3.peg.25, fig|882874.3.peg.4386, fig|696869.3.peg.601, fig|1182758.3.peg.4528, fig|984229.3.peg.3352, fig|885383.3.peg.3174, fig|886726.3.peg.21, fig|882877.3.peg.3216, fig|938147.3.peg.470, fig|984213.3.peg.1768, fig|702979.3.peg.3735, fig|984214.3.peg.277, fig|910415.3.peg.3315, fig|984223.3.peg.2916, fig|1147754.3.peg.2124, fig|1029979.3.peg.342, fig|886719.3.peg.3247, fig|984232.3.peg.1825, fig|885386.3.peg.3172, fig|984228.3.peg.78, fig|886724.3.peg.4250, fig|891412.3.peg.4742, fig|910419.3.peg.4257, fig|910416.3.peg.2781, fig|882879.3.peg.2135, fig|887066.3.peg.2924, fig|984218.3.peg.4732, fig|702978.3.peg.1805, fig|886723.3.peg.2069, fig|1182759.3.peg.4460, fig|984217.3.peg.4216, fig|984230.3.peg.53, fig|930769.3.peg.3885, fig|910414.3.peg.2247, fig|886720.3.peg.3184, fig|887067.3.peg.166, fig|984219.3.peg.4694, fig|925130.3.peg.1218, fig|886725.3.peg.83, fig|926037.3.peg.428, fig|696868.4.peg.3352, fig|1179780.3.peg.4521, fig|886727.3.peg.4031, fig|925133.3.peg.104, fig|891413.3.peg.144, fig|885385.3.peg.386, fig|1116476.3.peg.4762, fig|984221.3.peg.2362, fig|997329.3.peg.1804, fig|984220.3.peg.4327, fig|882875.3.peg.3197, fig|984215.3.peg.1996, fig|984212.3.peg.4687, fig|885384.3.peg.400, fig|925126.3.peg.2933, fig|984226.3.peg.177, fig|1116477.3.peg.4677 626 631 yes 438073 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 1208611, 1410937, 945541, 1079474, 1124958, 1124959, 938143, 1124963, 891420, 454167 Salmonella enterica, Salmonella enterica subsp. enterica serovar Abaetetuba str. ATCC 35640, Salmonella enterica subsp. enterica serovar Typhimurium var. 5- str. CFSAN004345, Salmonella enterica subsp. enterica serovar Javiana str. PRS_2010_0720, Salmonella enterica subsp. enterica serovar Javiana str. 10721, Salmonella enterica subsp. enterica serovar Muenster str. 0315, Salmonella enterica subsp. enterica serovar Muenster str. 420, Salmonella enterica subsp. enterica serovar Rubislaw str. ATCC 10717, Salmonella enterica subsp. enterica serovar Muenster str. 660, Salmonella enterica subsp. enterica serovar Javiana str. ATCC BAA-1593, Salmonella enterica subsp. enterica serovar Javiana str. GA_MM04042433 Bacteria UP000054489, UP000017358, UP000018563, UP000017378, UP000017575, UP000017621, UP000017318, UP000017323, UP000017509, UP000025016, UP000003328 486165890, 605529698, 564516371, 554252745, 554241005, 554234662, 554223391, 554129123, 553447060, 444810682, 204319893 AHW18180.1, ETC13761.1, ESG89224.1, ESG77931.1, ESG71906.1, ESG61021.1, ESF69752.1, ESB71989.1, ELX38321.1, EDZ05100.1 WP_001529319.1 fig|454167.5.peg.4419 626 631 yes 438074 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 310297, 484018 Bacteroides plebeius, Bacteroides plebeius DSM 17135 Bacteria UP000003452 494837818, 198269770 EDY94040.1 WP_007563918.1 fig|484018.6.peg.3122 566 566 yes 438075 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 451707 Bacillus cereus, Bacillus cereus NVH0597-99 Bacteria UP000036076, UP000005188 487916589, 196029594 EDX68196.1 WP_001990055.1 fig|451707.4.peg.2401 586 586 yes 438076 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 313985, 398767 Geobacter lovleyi, Geobacter lovleyi SZ Bacteria UP000002420 501447357, 189422079 ACD96477.1 WP_012470806.1 fig|398767.5.peg.2701 429 429 yes 438077 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 290512 Prosthecochloris aestuarii DSM 271 Bacteria UP000002725 194312184 ACF46579.1 B4S9A9 THIC_PROA2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6848918 fig|290512.6.peg.1659 553 561 no 438078 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 40137, 504832, 1031710 Oligotropha carboxidovorans, Oligotropha carboxidovorans OM5, Oligotropha carboxidovorans OM4 Bacteria UP000001678, UP000000487 501559671, 336097957, 336094378, 209874345, 229558533 AEI05780.1, AEI02204.1, ACI94141.1 WP_012564167.1 B6JI86 THIC_OLICO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7496591 fig|504832.4.peg.3011, fig|1031710.3.peg.1130 622 632 yes 438079 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 436114 Sulfurihydrogenibium sp. YO3AOP1 Bacteria UP000001201 501435298, 188932259 ACD66889.1 WP_012459950.1 fig|436114.3.peg.1333 448 453 yes 438080 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 1396, 1053235, 1053190, 1053186, 1053185, 1053182, 665957, 526967, 405533 Bacillus cereus, Bacillus cereus VD140, Bacillus cereus BAG5X12-1, Bacillus cereus BAG4X12-1, Bacillus cereus BAG4O-1, Bacillus cereus BAG3O-2, Bacillus sp. 7_6_55CFAA_CT2, Bacillus cereus 172560W, Bacillus cereus AH1134 Bacteria UP000036076, UP000014037, UP000014021, UP000006987, UP000006952, UP000006606, UP000006435, UP000001752, UP000003256 446737223, 859509051, 811098092, 706244012, 500525797, 500512907, 401116238, 401112662, 401109210, 363617554, 228602060, 206734599 KMP33194.1, AKE19454.1, KGT41018.1, EOP91169.1, EOP78788.1, EJQ24080.1, EJQ20538.1, EJQ17137.1, EHL68941.1, EEK59553.1, EDZ51768.1 WP_000814479.1 fig|1053190.3.peg.4825, fig|526967.3.peg.5503, fig|1053186.3.peg.4882, fig|1053185.3.peg.5091, fig|1053182.3.peg.345, fig|1053235.3.peg.5518, fig|405533.4.peg.2821, fig|665957.3.peg.4496 586 586 yes 438081 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 40324, 391008 Stenotrophomonas maltophilia, Stenotrophomonas maltophilia R551-3 Bacteria UP000034806, UP000001867 501503866, 194349901, 238693432 ACF53024.1 WP_012512035.1 B4SI60 THIC_STRM5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7082134 fig|391008.3.peg.3344, fig|1118157.3.peg.3465 613 614 yes 438082 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 439497 Ruegeria sp. R11 Bacteria UP000005776 495834640, 214028969 EEB69804.1 WP_008559219.1 fig|439497.5.peg.3308 596 604 yes 438083 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 225194, 404380 Geobacter bemidjiensis, Geobacter bemidjiensis Bem Bacteria UP000008825 501524300, 197089530 ACH40801.1 WP_012532237.1 fig|404380.3.peg.3724 432 435 yes 438084 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 281309, 1392, 1428, 288681, 451709, 1454382, 572264, 1053216, 347495, 930170, 637380, 527028, 527032, 526970, 405535 Bacillus thuringiensis serovar konkukian str. 97-27, Bacillus anthracis, Bacillus thuringiensis, Bacillus cereus E33L, Bacillus cereus 03BB108, Bacillus cereus D17, Bacillus cereus 03BB102, Bacillus cereus ISP3191, Bacillus cereus F837/76, Bacillus thuringiensis serovar finitimus YBT-020, Bacillus cereus biovar anthracis str. CI, Bacillus thuringiensis serovar pulsiensis BGSC 4CC1, Bacillus thuringiensis serovar andalousiensis BGSC 4AW1, Bacillus cereus BGSC 6E1, Bacillus cereus AH820 Bacteria UP000001301, UP000034470, UP000031834, UP000031894, UP000005810, UP000031860, UP000031880, UP000006972, UP000007854, UP000007483, UP000001657, UP000006665, UP000001380, UP000000284, UP000001363 446737210, 49481742, 837633844, 753745391, 753730727, 753716206, 753667852, 753297644, 753285888, 401181125, 364514930, 324329172, 300378856, 228841767, 228823345, 228595965, 225788724, 218537963, 196023474, 51973809, 49333298, 254784154, 226695515, 81685434, 81613487 KLV17007.1, AJI35381.1, AJI26491.1, AJH83204.1, AJI10468.1, AJG61589.1, AJG55165.1, EJQ88278.1, AEW58329.1, ADY24432.1, ADK07760.1, EEM86877.1, EEM69179.1, EEK53643.1, ACO28941.1, ACK90361.1, EDX62151.1, AAU15359.1, AAT63944.1 WP_000814466.1, YP_039217.1 B7JGF0, C1EZL5, Q631C7, Q6HB59 THIC_BACC0, THIC_BACC3, THIC_BACCZ, THIC_BACHK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7636320, 7210177, 600194, 4706088, 4659497, 653948, 4692927 fig|281309.3.peg.5180, fig|930170.3.peg.5195, fig|572264.4.peg.5233, fig|527032.3.peg.800, fig|347495.3.peg.5102, fig|637380.6.peg.5608, fig|527022.3.peg.1418, fig|288681.12.peg.5189, fig|526970.3.peg.679, fig|527028.3.peg.378, fig|1053216.3.peg.5047, fig|451709.4.peg.3238, fig|405535.8.peg.5295 586 586 yes 438085 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 54388, 941189, 1072571, 1072572, 1072568, 1072570, 1072569, 295319, 554290 Salmonella enterica, Salmonella enterica subsp. enterica serovar Paratyphi A, Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 11511, Salmonella enterica subsp. enterica serovar Paratyphi A str. YN09620, Salmonella enterica subsp. enterica serovar Paratyphi A str. ZJ98-53, Salmonella enterica subsp. enterica serovar Paratyphi A str. GXS2268, Salmonella enterica subsp. enterica serovar Paratyphi A str. JX05-19, Salmonella enterica subsp. enterica serovar Paratyphi A str. GZ9A00052, Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC 9150, Salmonella enterica subsp. enterica serovar Paratyphi A str. AKU_12601 Bacteria UP000054489, UP000046279, UP000017500, UP000014397, UP000014392, UP000014399, UP000014398, UP000014402, UP000008185, UP000001869 446030552, 861209468, 747137186, 747133918, 554154658, 512527739, 512527507, 512515512, 512515482, 512515453, 56130247, 815656797, 815652490, 815650973, 815644221, 815641386, 815638496, 815630621, 815627458, 815623353, 815618231, 815615144, 815611973, 815606928, 815601808, 815601272, 815594684, 815589561, 815586472, 815581860, 815578829, 815574215, 815571769, 815566026, 815564111, 815557904, 815554397, 815549722, 815548208, 815543713, 815536591, 815529950, 815525304, 815522923, 815516917, 815513072, 815507964, 815505029, 815502966, 815498720, 815491809, 815490354, 815484638, 815480578, 815476520, 815471438, 815470306, 815464350, 815460295, 815456233, 815452181, 815448126, 815442982, 815440038, 815437844, 815433787, 815427860, 815423819, 815418833, 815417356, 815412064, 815406670, 815403593, 815398520, 815395497, 815389927, 815383400, 815379343, 815374330, 815371253, 815368896, 815364807, 815359115, 815355071, 815351032, 815346782, 815343553, 815338896, 815336266, 815330819, 815327315, 815322736, 815318715, 815314652, 815310708, 815308264, 815302533, 815298498, 815295193, 815289381, 815285349, 815278286, 815273758, 815266202, 815262679, 815260803, 815255797, 815250093, 815245957, 815242186, 815237586, 815235968, 815231646, 815220459, 815218515, 815214080, 815210513, 815207105, 815200666, 815195655, 815193210, 815187675, 815184900, 815179707, 815175776, 815175183, 815168774, 815163800, 815160881, 815156948, 815150700, 815144845, 815141244, 815137211, 238690779, 197096394, 81599691 AKO81912.1, AJD93908.1, AJD98864.1, ESF94491.1, EPE53152.1, EPE52925.1, EPE41312.1, EPE41255.1, EPE41284.1, AAV79753.1 WP_000108407.1 Q5PKA6, B5BJR3 THIC_SALPA, THIC_SALPK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 4781139, 4391204, 906742, 5812558 fig|1072571.3.peg.4127, fig|554290.7.peg.4210, fig|1072572.3.peg.4185, fig|295319.15.peg.4243, fig|1072568.3.peg.4182, fig|1072570.3.peg.4218, fig|1072569.3.peg.4213 626 631 yes 438086 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 329854, 471870 Bacteroides intestinalis, Bacteroides intestinalis DSM 17393 Bacteria UP000004596 494933596, 189438685 EDV07670.1 WP_007659629.1 fig|471870.8.peg.64 569 569 yes 438087 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2214, 188937 Methanosarcina acetivorans, Methanosarcina acetivorans C2A Archaea UP000002487 UP000002487 499333717, 19918454, 24638259 AAM07672.1 WP_011024209.1 Q8TI28 THIC2_METAC Phosphomethylpyrimidine synthase 2 {ECO:0000255|HAMAP-Rule:MF_00089} 237543 fig|188937.1.peg.4218 428 428 yes 438088 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 1446745, 1005558, 868159, 868158, 868157, 868155, 1048689, 926030, 701177 Escherichia coli, Escherichia coli O55:H7 str. 06-3555, Escherichia coli 5905, Escherichia coli DEC5E, Escherichia coli DEC5D, Escherichia coli DEC5C, Escherichia coli DEC5A, Escherichia coli O55:H7 str. RM12579, Escherichia coli O55:H7 str. USDA 5905, Escherichia coli O55:H7 str. CB9615 Bacteria UP000036210, UP000024122, UP000007561, UP000003367, UP000004027, UP000005022, UP000003428, UP000007173, UP000003225, UP000001521 447199656, 606922029, 408161054, 377979721, 377970158, 377968529, 377956628, 374361438, 320660775, 290765282, 209751744 EYZ55017.1, EKH89037.1, EHV42997.1, EHV33529.1, EHV31921.1, EHV20175.1, AEZ43145.1, EFX28229.1, ADD59243.1, ACI74179.1 WP_001276912.1 fig|701177.3.peg.4810, fig|1005558.3.peg.5315, fig|868157.3.peg.4886, fig|868155.3.peg.4683, fig|926030.3.peg.2793, fig|868158.3.peg.4761, fig|868159.3.peg.4811 626 631 yes 438089 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 284016, 450851 Phenylobacterium zucineum, Phenylobacterium zucineum HLK1 Bacteria UP000001868 501515519, 196479790 ACG79318.1 WP_012523456.1 fig|450851.6.peg.3605 601 611 yes 438090 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 920, 243159, 380394 Acidithiobacillus ferrooxidans, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 53993 Bacteria UP000001362, UP000001856 501529976, 218517465, 198247713, 238689979, 226695513 ACK78051.1, ACH83306.1 WP_012536456.1 B7J7C4, B5EQ61 THIC_ACIF2, THIC_ACIF5 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5530383 fig|380394.3.peg.1071, fig|243159.3.peg.905 626 627 yes 438091 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 434922 Coxiella burnetii Dugway 5J108-111 Bacteria UP000008555 207082100, 226695889 ABS77053.2 A9KGN7 THIC_COXBN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2919818, 3716115 fig|434922.4.peg.1734 546 554 yes 438092 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 391615 gamma proteobacterium HTCC5015 Bacteria UP000004692 495560132, 198261966 EDY86250.1 WP_008284711.1 fig|391615.3.peg.1424 633 637 yes 438093 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526977, 1053213, 1053214, 1053221, 1053166, 718220, 526975, 361100, 405534, 451708, 1313, 334406 Bacillus cereus, Bacillus cereus ATCC 4342, Bacillus cereus IS195, Bacillus cereus IS845/00, Bacillus cereus MSX-A12, Bacillus cereus AND1407, Bacillus cereus IS075, Bacillus cereus BDRD-ST26, Bacillus cereus Q1, Bacillus cereus AH187, Bacillus cereus H3081.97, Streptococcus pneumoniae, Bacillus cereus NC7401 Bacteria UP000036076, UP000031844, UP000014013, UP000013987, UP000006979, UP000006988, UP000006950, UP000002291, UP000000441, UP000002214, UP000004611, UP000029709, UP000007111 446737212, 859600742, 859582677, 859567810, 821639565, 821626708, 821624021, 753607653, 675473817, 674470378, 500381942, 500375860, 401198501, 401092804, 401082060, 228641575, 228624773, 221242745, 217065634, 206744976, 815053787, 801054414, 358355770, 254784155, 226695518 KMQ22233.1, KMQ04606.1, KMP90044.1, KLA20409.1, KLA07804.1, KLA05172.1, AJH73942.1, KFM91623.1, KFK71241.1, EOO98247.1, EOO92404.1, EJR05420.1, EJQ00928.1, EJP90331.1, EEK97880.1, EEK81542.1, ACM15455.1, ACJ79884.1, EDZ56380.1 WP_000814468.1 B7HX62, B9J5N4 THIC_BACC7, THIC_BACCQ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7204200, 4700200, 5525691, 2312877, 4692927 fig|718220.3.peg.3874, fig|526975.3.peg.115, fig|361100.6.peg.5103, fig|1053221.3.peg.5506, fig|405534.9.peg.5552, fig|526977.3.peg.4975, fig|1053166.3.peg.4338, fig|1053213.3.peg.1303, fig|1053214.3.peg.1303, fig|334406.4.peg.5088, fig|451708.10.peg.3866 586 586 yes 438094 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 155077, 498211 Cellvibrio japonicus, Cellvibrio japonicus Ueda107 Bacteria UP000001036 501465048, 190685304, 238692422 ACE82982.1 WP_012488493.1 B3PCK0 THIC_CELJU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5710842 fig|498211.3.peg.2795 635 636 yes 438095 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 199596, 395965 Methylocella silvestris, Methylocella silvestris BL2 Bacteria UP000002257 501587692, 217504501 ACK51910.1 WP_012591979.1 fig|395965.4.peg.3224 608 609 yes 438096 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 190304, 851 Fusobacterium nucleatum subsp. nucleatum ATCC 25586, Fusobacterium nucleatum Bacteria UP000002521 UP000002521 19705078, 499325324, 19712998, 24638256 AAL93872.1 NP_602573.1, WP_011015816.1 Q8RI60 THIC_FUSNN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 193062 fig|190304.1.peg.252 433 433 yes 438097 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 314607 beta proteobacterium KB13 Bacteria UP000004188 497538945, 207087869 EDZ65152.1 WP_009853143.1 fig|314607.3.peg.19 623 629 yes 438098 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 180281 Cyanobium sp. PCC 7001 Bacteria UP000003950 197625089 EDY37648.1 464 469 yes 438099 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 87882, 95486, 292, 985077, 985076, 1055524, 216591 Burkholderia cenocepacia, Burkholderia cepacia, Burkholderia cenocepacia BC7, Burkholderia cenocepacia K56-2Valvano, Burkholderia cenocepacia H111, Burkholderia cenocepacia J2315 Bacteria UP000065887, UP000063625, UP000011178, UP000011196, UP000004383, UP000001035 493529707, 815848802, 757907964, 686815314, 685661260, 542086058, 529208997, 590115566, 238693113, 198035528 KKI79643.1, KIS46764.1, KGB94798.1, AIO48387.1, ERI25348.1, EPZ85732.1 WP_006483722.1 B4ED40 THIC_BURCJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5923413 fig|1055524.3.peg.5298, fig|985076.4.peg.3467, fig|216591.1.peg.7418, fig|985077.3.peg.2106 642 643 yes 438100 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 338, 434928, 611301, 1308548, 1308541, 317013, 1401257, 1137651, 1304892, 190486 Xanthomonas citri pv. citri, Xanthomonas citri subsp. citri, Xanthomonas citri subsp. citri UI6, Xanthomonas citri subsp. citri A306, Xanthomonas axonopodis pv. phaseoli, Xanthomonas axonopodis pv. glycines str. 8ra, Xanthomonas citri subsp. citri Aw12879, Xanthomonas axonopodis Xac29-1, Xanthomonas axonopodis pv. citri str. 306 Bacteria UP000052252, UP000032628, UP000032637, UP000031282, UP000030394, UP000021790, UP000011877, UP000011979, UP000000576 499364255, 833362393, 780550385, 780545310, 780540251, 780534967, 780530013, 780524677, 780519551, 780514368, 780509282, 780504349, 780499040, 780494221, 780489271, 780484600, 780479647, 780474767, 780469750, 780464799, 745821681, 740552192, 739132123, 727618497, 712962303, 582989705, 471213156, 469768505, 21109806, 747012215, 747007315, 747001695, 723791159, 723785308, 713491166, 713484350, 713477050, 713470498, 713463435, 713456254, 713449687, 703472107, 703465232, 703458828, 703457618, 703448047, 703438430, 703430721, 703416182, 703409126, 24638248 AKM26367.1, AJY83550.1, AJY87975.1, AJY92419.1, AJY96868.1, AJZ01292.1, AJZ05720.1, AJZ10159.1, AJZ14612.1, AJZ19036.1, AJZ23464.1, AJZ27888.1, AJZ32327.1, AJZ36791.1, AJZ41258.1, AJZ46202.1, AJZ50822.1, AJZ55443.1, AJZ68233.1, AJD70039.1, KHS24172.1, KHS08889.1, KHF50136.1, KGU57548.1, EWC50432.1, AGI09906.1, AGH78922.1, AAM38290.1 WP_011052285.1 Q8PH13 THIC_XANAC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 259300 fig|1150615.3.peg.2241, fig|1304892.4.peg.3652, fig|1137651.4.peg.4149, fig|190486.1.peg.3398 624 625 yes 438101 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 196627, 1718, 1310161, 1204414 Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum, Corynebacterium glutamicum MB001, Corynebacterium glutamicum K051 Bacteria UP000001009, UP000031556, UP000015422, UP000007328 19552525, 499323781, 529577838, 182908920, 385143434, 41325525, 24638246, 21324073 AGT05291.1, ACC04804.1 NP_600527.1, WP_011014273.1 Q8NQW7 THIC_CORGL Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5916432, 191045 fig|196627.13.peg.1280, fig|196627.14.peg.1284 586 587 yes 438102 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2214, 188937 Methanosarcina acetivorans, Methanosarcina acetivorans C2A Archaea UP000002487 UP000002487 499331301, 19915685, 24638261 AAM05196.1 WP_011021793.1 Q8TPW4 THIC1_METAC Phosphomethylpyrimidine synthase 1 {ECO:0000255|HAMAP-Rule:MF_00089} 235067 fig|188937.1.peg.1742 428 428 yes 438103 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 384, 395492 Rhizobium leguminosarum, Rhizobium leguminosarum bv. trifolii WSM2304 Bacteria UP000008330 501555509, 209539346 ACI59278.1 WP_012560019.1 fig|395492.8.peg.6626 601 608 yes 438104 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 1455601, 1444264, 1444158, 1444048, 1444206, 1444240, 1444110, 1444277, 1444084, 1444263, 1444233, 1444261, 1444164, 1444221, 1444059, 1444141, 1444056, 1444134, 1444162, 1444191, 1444246, 1446708, 1446748, 1446497, 1446501, 1446747, 1370107, 1331065, 1281085, 1280998, 1269007, 1335304, 1335303, 1281154, 1281153, 1281261, 1281218, 1281177, 1281159, 1169358, 1182699, 1182680, 1182671, 1169357, 1125647, 1125637, 1116117, 1116116, 1116110, 1116009, 1116006, 1116113, 1116471, 1116057, 1116136, 1116138, 1116007, 1116111, 1116065, 1116064, 1116060, 1116062, 1116063, 1181778, 1181777, 1169330, 1169664, 1005565, 910348, 868166, 656429, 656404, 749547, 749537, 469008, 413997, 866768, 358709, 344610, 1432547, 1268238, 316401 Escherichia coli, Escherichia coli G3/10, Escherichia coli 2-222-05_S4_C3, Escherichia coli 7-233-03_S3_C2, Escherichia coli 8-415-05_S1_C1, Escherichia coli 2-222-05_S4_C1, Escherichia coli 5-366-08_S4_C2, Escherichia coli 3-105-05_S1_C3, Escherichia coli 3-073-06_S4_C3, Escherichia coli 3-105-05_S1_C2, Escherichia coli 2-210-07_S4_C3, Escherichia coli 2-210-07_S4_C2, Escherichia coli 2-156-04_S4_C3, Escherichia coli 1-392-07_S3_C2, Escherichia coli 3-073-06_S4_C1, Escherichia coli 3-475-03_S1_C1, Escherichia coli 3-373-03_S3_C1, Escherichia coli 3-105-05_S1_C1, Escherichia coli 1-182-04_S3_C1, Escherichia coli 1-182-04_S3_C2, Escherichia coli 1-182-04_S3_C3, Escherichia coli 1-250-04_S4_C2, Escherichia coli O25:NM str. E2539C1, Escherichia coli O6:H16 str. F5656C1, Escherichia coli O104:H21 str. 94-3025, Escherichia coli O103:H11 str. 04-3023, Escherichia coli O6:H16 str. 99-3165, Escherichia coli O6:H16:CFA/II str. B2C, Escherichia coli CE549, Escherichia coli HVH 152 (4-3447545), Escherichia coli HVH 50 (4-2593475), Escherichia coli 909945-2, Escherichia coli O104:H21 str. CFSAN002237, Escherichia coli O104:H21 str. CFSAN002236, Escherichia coli KOEGE 7 (16a), Escherichia coli KOEGE 3 (4a), Escherichia coli UMEA 3682-1, Escherichia coli UMEA 3212-1, Escherichia coli UMEA 3052-1, Escherichia coli KOEGE 40 (102a), Escherichia coli KTE41, Escherichia coli KTE100, Escherichia coli KTE73, Escherichia coli KTE64, Escherichia coli KTE40, Escherichia coli P0301904.3, Escherichia coli BCE006_MS-23, Escherichia coli BCE032_MS-12, Escherichia coli BCE030_MS-09, Escherichia coli BCE008_MS-01, Escherichia coli 2741950, Escherichia coli 2730450, Escherichia coli BCE007_MS-11, Escherichia coli BCE008_MS-13, Escherichia coli MP021017.1, Escherichia coli MP021561.2, Escherichia coli MP021566.1, Escherichia coli 2731150, Escherichia coli MP021017.12, Escherichia coli MP021017.11, Escherichia coli MP021017.10, Escherichia coli MP021017.4, Escherichia coli MP021017.6, Escherichia coli MP021017.9, Escherichia coli KTE234, Escherichia coli KTE233, Escherichia coli KTE10, Escherichia coli AD30, Escherichia coli 3006, Escherichia coli P12b, Escherichia coli DEC7B, Escherichia coli TA007, Escherichia coli H489, Escherichia coli MS 187-1, Escherichia coli MS 115-1, Escherichia coli BL21(DE3), Escherichia coli B str. REL606, Escherichia coli 'BL21-Gold(DE3)pLysS AG', Escherichia coli 101-1, Escherichia coli 53638, Klebsiella pneumoniae IS22, Escherichia coli O5:K4(L):H4 str. ATCC 23502, Escherichia coli ETEC H10407 Bacteria UP000036210, UP000030015, UP000028086, UP000027832, UP000027739, UP000027691, UP000028079, UP000027638, UP000027890, UP000027771, UP000027880, UP000027805, UP000027633, UP000027911, UP000027909, UP000027752, UP000028010, UP000028131, UP000023853, UP000024217, UP000024028, UP000024138, UP000024072, UP000024084, UP000023910, UP000024269, UP000023931, UP000018912, UP000018380, UP000017748, UP000017305, UP000017275, UP000016541, UP000016512, UP000016395, UP000016411, UP000016344, UP000015992, UP000016105, UP000015981, UP000014106, UP000014089, UP000014172, UP000014122, UP000014206, UP000012302, UP000012433, UP000012211, UP000012314, UP000012377, UP000012226, UP000012268, UP000012419, UP000012422, UP000012370, UP000012254, UP000012262, UP000012224, UP000012235, UP000012264, UP000012330, UP000012381, UP000012411, UP000012423, UP000010656, UP000010703, UP000010614, UP000007827, UP000007356, UP000007385, UP000006423, UP000005689, UP000003272, UP000003717, UP000032708, UP000001509, UP000001632, UP000004189, UP000004441, UP000011199, UP000006877 447199647, 850017097, 822935928, 817150596, 763540826, 763535732, 763525012, 763518829, 763516068, 763514192, 763508777, 763490959, 763488183, 753778202, 751403027, 748131514, 748024428, 732678377, 729984733, 729808077, 706062147, 706056948, 706051413, 706046770, 706041302, 705992344, 701198852, 700824590, 700822465, 700815366, 699378783, 671702118, 671392604, 660324433, 660229852, 660228871, 660193873, 660033211, 652284456, 652275230, 652275028, 652045962, 652042448, 652018870, 651785561, 650114319, 650063908, 650041657, 650006815, 611086412, 611077845, 611063865, 611030291, 607379118, 607378609, 607370875, 607003201, 606534774, 572730311, 557932982, 556143291, 554714276, 553371097, 540150305, 540146159, 536000195, 535997741, 535829495, 535675020, 535487684, 535400201, 508519367, 508444386, 508403487, 508381646, 508331224, 477107927, 477071292, 476830775, 476824794, 476806994, 476772790, 476771322, 476722241, 476707334, 476317267, 476310396, 476301362, 476253709, 476088998, 476083274, 476079592, 476063114, 476049989, 476048592, 431066364, 431059462, 430890537, 408456580, 408208525, 383105410, 378027612, 323969068, 323958921, 300463194, 300413505, 253979993, 253975837, 253326420, 194421286, 188488980, 571214011, 441651858, 309704410, 242379525 AKN49866.1, KLG60932.1, AKF23184.1, KJA07496.1, KJA02576.1, KIZ92453.1, KIZ86598.1, KIZ83992.1, KIZ82240.1, KIZ77208.1, KIZ60440.1, KIZ57838.1, AJH12631.1, AJF79112.1, KIH36498.1, KIG36226.1, AIZ85184.1, KHI74250.1, KHH02946.1, KGT30512.1, KGT25790.1, KGT20674.1, KGT16310.1, KGT11195.1, KGT05824.1, KGP38444.1, KGP17436.1, KGP15770.1, KGP09079.1, KGM58627.1, KFF54077.1, KFF39227.1, KEO12250.1, KEN21289.1, KEN20338.1, KEM86214.1, KEL31310.1, KDZ88150.1, KDZ79286.1, KDZ79104.1, KDX63600.1, KDX60264.1, KDX38176.1, KDW62194.1, KDU34629.1, KDT86085.1, KDT64646.1, KDT31290.1, EZJ87778.1, EZJ79727.1, EZJ66509.1, EZJ34437.1, EZA71632.1, EZA71133.1, EZA63810.1, EZA31870.1, EYV88691.1, ETS28893.1, ESS96548.1, ESP31582.1, ESK19663.1, ESA97412.1, ERF95577.1, ERF91563.1, ERA99679.1, ERA97331.1, EQZ61887.1, EQY10611.1, EQW27070.1, EQV41674.1, EOW88037.1, EOW14349.1, EOV74149.1, EOV52759.1, EOV03117.1, END88093.1, END53083.1, ENB29950.1, ENB24381.1, ENB08005.1, ENA75219.1, ENA73822.1, ENA27097.1, ENA12407.1, EMX34901.1, EMX28150.1, EMX19246.1, EMW72487.1, EMV12681.1, EMV07192.1, EMV03682.1, EMU87720.1, EMU74875.1, EMU73540.1, ELD74999.1, ELD68819.1, ELC13170.1, EKJ80394.1, EKI33170.1, AFG42919.1, EHV90239.1, EGB64376.1, EGB54596.1, EFK26687.1, EFJ96815.1, ACT45663.1, ACT41508.1, ACT31022.1, EDX37306.1, EDU64083.1 WP_001276903.1 fig|868166.3.peg.4217, fig|1116136.3.peg.4836, fig|1116111.3.peg.4064, fig|913091.3.peg.166, fig|1181777.3.peg.2118, fig|1182699.3.peg.187, fig|1182680.3.peg.4358, fig|511693.5.peg.4089, fig|1005565.3.peg.4537, fig|358709.5.peg.4541, fig|1125637.3.peg.4398, fig|749537.3.peg.2889, fig|1169357.3.peg.4110, fig|1182671.3.peg.4362, fig|469008.4.peg.4198, fig|344610.3.peg.1258, fig|1116007.3.peg.4913, fig|1125647.3.peg.4587, fig|1116116.3.peg.4394, fig|1116471.3.peg.4908, fig|1116057.3.peg.4743, fig|1116113.3.peg.4550, fig|1116062.3.peg.4550, fig|316401.4.peg.4829, fig|656429.3.peg.5105, fig|1116009.3.peg.4604, fig|910348.4.peg.4501, fig|1116117.3.peg.4384, fig|1116110.3.peg.4459, fig|1181778.3.peg.233, fig|1116065.3.peg.4551, fig|1116006.3.peg.4629, fig|1116064.3.peg.4753, fig|1317131.3.peg.4424, fig|1268238.3.peg.3409, fig|1169358.3.peg.4908, fig|1116060.3.peg.4669, fig|413997.3.peg.4069, fig|749547.3.peg.1119, fig|1169330.3.peg.1472, fig|1116138.3.peg.4988, fig|1116063.3.peg.4495, fig|656404.3.peg.4723, fig|1169664.3.peg.4505 626 631 yes 438105 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 194439, 1097 Chlorobium tepidum TLS, Chlorobaculum tepidum Bacteria UP000001007 21674263, 499235569, 21647432, 29337067 AAM72670.1 NP_662328.1, WP_010933109.1 Q8KCH9 THIC_CHLTE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} fig|194439.1.peg.1422 555 556 yes 438106 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 197, 1365662, 1367443, 1365653, 478547, 889254 Campylobacter jejuni, Campylobacter jejuni K5, Campylobacter jejuni Cj5, Campylobacter jejuni 10186, Campylobacter jejuni subsp. jejuni CG8421, Campylobacter jejuni subsp. jejuni 2008-979 Bacteria UP000065538, UP000024868, UP000024518, UP000025167, UP000004917, UP000004953 488948816, 631621508, 631608979, 631604645, 627770481, 380638695, 205346563 KDA37062.1, KDA25054.1, KDA20796.1, AHY39706.1, EIB56233.1, EDZ33195.1 WP_002859891.1 fig|889254.3.peg.855, fig|478547.3.peg.24 430 430 yes 438107 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 465541 Streptomyces sp. Mg1 Bacteria UP000005764 496017113, 829480755, 194343706 AKL66898.1, EDX24672.1 WP_008741692.1 fig|465541.3.peg.4215 593 595 yes 438108 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 481448 Methylacidiphilum infernorum V4 Bacteria UP000009149 189184941 ACD82126.1 fig|481448.4.peg.66 629 647 yes 438109 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 1249525, 984254, 465517 Salmonella enterica, Salmonella enterica subsp. enterica serovar Virchow str. 07M3147, Salmonella enterica subsp. enterica serovar Virchow str. ATCC 51955, Salmonella enterica subsp. enterica serovar Virchow str. SL491 Bacteria UP000054489, UP000019493, UP000017372, UP000003614 446030566, 570344038, 554057692, 199604983 ETO87274.1, ESF02256.1, EDZ03528.1 WP_000108421.1 fig|465517.10.peg.750 626 631 yes 438110 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 1005566, 1005563, 869693, 869692, 868142, 868141, 868140, 868139, 868138, 868137, 868136, 868134, 868133, 868135, 670899, 670897, 574521 Escherichia coli, Escherichia coli 07798, Escherichia coli ARS4.2123, Escherichia coli TW07793, Escherichia coli 3003, Escherichia coli DEC2E, Escherichia coli DEC2D, Escherichia coli DEC2C, Escherichia coli DEC2B, Escherichia coli DEC2A, Escherichia coli DEC1E, Escherichia coli DEC1D, Escherichia coli DEC1B, Escherichia coli DEC1A, Escherichia coli DEC1C, Escherichia coli RN587/1, Escherichia coli 2362-75, Escherichia coli O127:H6 str. E2348/69 Bacteria UP000036210, UP000006773, UP000007116, UP000005962, UP000003038, UP000005704, UP000005272, UP000003315, UP000004768, UP000004201, UP000003618, UP000003409, UP000005492, UP000006407, UP000003716, UP000003349, UP000004874, UP000008205 447199632, 408209852, 408196997, 386248500, 386245470, 377885194, 377873099, 377871529, 377869912, 377856992, 377855585, 377852380, 377840935, 377838489, 377838448, 323190149, 312290027, 254784162, 215267398 EKI34432.1, EKI22269.1, EII94672.1, EII87200.1, EHU49694.1, EHU37738.1, EHU36191.1, EHU34613.1, EHU21848.1, EHU20454.1, EHU17304.1, EHU06004.1, EHU03606.1, EHU03566.1, EFZ75427.1, EFR17914.1 WP_001276888.1 B7UPE9 THIC_ECO27 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} fig|868136.3.peg.4891, fig|1005566.3.peg.4521, fig|868142.3.peg.4230, fig|868138.3.peg.4685, fig|868141.3.peg.4742, fig|1005563.3.peg.4373, fig|1126911.3.peg.1175, fig|868139.3.peg.4672, fig|868135.3.peg.4861, fig|670897.3.peg.1063, fig|574521.7.peg.4400, fig|868140.3.peg.4644, fig|216593.1.peg.4044, fig|869692.3.peg.4573, fig|1126932.3.peg.3448, fig|868137.3.peg.4727, fig|868133.3.peg.4544, fig|868134.3.peg.4623, fig|670899.3.peg.1915, fig|869693.3.peg.3089 626 631 yes 438111 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 911092, 273068 Caldanaerobacter subterraneus, Thermoanaerobacter tengcongensis MB4 Bacteria UP000053343, UP000000555 499335312, 20516569, 24638255 AAM24769.1 WP_011025804.1 Q8R9P1 THIC_CALS4 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 239317 fig|273068.3.peg.1512 431 432 yes 438112 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 38300, 457429 Streptomyces pristinaespiralis, Streptomyces pristinaespiralis ATCC 25486 Bacteria UP000060513, UP000002805 491457309, 197718331 EDY62239.1 WP_005315088.1 fig|457429.3.peg.552 595 597 yes 438113 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 43765, 553204 Corynebacterium amycolatum, Corynebacterium amycolatum SK46 Bacteria UP000003275 491652869, 213952833 EEB64215.1 WP_005509590.1 fig|553204.6.peg.337 559 568 yes 438114 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 573, 1199150, 1328365, 507522 Klebsiella pneumoniae, Klebsiella pneumoniae subsp. pneumoniae KP5-1, Klebsiella pneumoniae MGH 20, Klebsiella pneumoniae 342 Bacteria UP000036212, UP000027424, UP000017418, UP000001734 501537339, 725535775, 660552781, 555188405, 206569933, 238065981 KHE27777.1, AIE01226.1, ESN30916.1, ACI11709.1 WP_012543209.1 B5XYE4 THIC_KLEP3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 10411273, 5736927 fig|507522.6.peg.5171 626 631 yes 438115 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 380749 Hydrogenobaculum sp. Y04AAS1 Bacteria UP000001872 501506026, 195933089 ACG57789.1 WP_012514145.1 fig|380749.4.peg.1105 450 453 yes 438116 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 511435, 511995 Candidatus Azobacteroides pseudotrichonymphae, Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2 Bacteria UP000000723 501569223, 212549227 WP_012573655.1 fig|511995.9.peg.949 569 571 yes 438117 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 584, 1266738, 1125693, 525369, 529507 Proteus mirabilis, Proteus mirabilis BB2000, Proteus mirabilis WGLW4, Proteus mirabilis ATCC 29906, Proteus mirabilis HI4320 Bacteria UP000033762, UP000015420, UP000005371, UP000006419, UP000008319 490367252, 721560423, 721496964, 721496054, 702065540, 529189477, 404599936, 227164710, 194684093 KGZ03747.1, KGY40485.1, KGY39576.1, KGQ17283.1, AGS61237.1, EKB00389.1, EEI49564.1 WP_004246916.1 fig|1245027.3.peg.2821, fig|584.1.peg.532, fig|529507.6.peg.2708, fig|525369.4.peg.3399, fig|1279010.3.peg.3114, fig|1125693.3.peg.504 620 650 yes 438118 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1092, 290315 Chlorobium limicola, Chlorobium limicola DSM 245 Bacteria UP000053937, UP000008841 501443135, 189341308, 238692160 ACD90711.1 WP_012466584.1 B3EE09 THIC_CHLL2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6840869 fig|290315.4.peg.1783 557 560 yes 438119 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 358708 Shigella dysenteriae 1012 Bacteria UP000003432 194416987 EDX33105.1 fig|358708.5.peg.4662 626 631 yes 438120 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 227377, 777 Coxiella burnetii RSA 493, Coxiella burnetii Bacteria UP000002671 UP000002671, UP000033654 215918943, 499259967, 206583828, 218511852 AAO89886.2 NP_819372.2, WP_010957507.1 Q83EJ0 THIC_COXBU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7010860, 221372 fig|227377.1.peg.316 546 554 yes 438121 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 439495 Pseudovibrio sp. JE062 Bacteria UP000005311 495824110, 211960168 EEA95365.1 WP_008548689.1 fig|439495.5.peg.1992 594 599 yes 438122 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 869676, 331111, 340184, 1444249, 1444125, 1444183, 1444098, 1444070, 1446574, 1438686, 1438669, 1446561, 1446557, 1446555, 1446739, 1446575, 1446576, 1446499, 1446543, 1446552, 1446553, 1446554, 1446564, 1446565, 1446566, 1446568, 1446569, 1446570, 1446573, 1446572, 1446556, 1446560, 1446562, 1405295, 1331063, 1281034, 1268996, 1169318, 1116055, 1116054, 1116049, 1116056, 1116043, 1116042, 1116041, 1116040, 1116038, 1116046, 1116137, 1116127, 1169367, 1181730, 1182719, 1182694, 1169348, 1182722, 1169332, 869689, 869684, 869683, 550682, 754080, 754083, 796392, 656443, 679204, 679207, 340186 Escherichia coli, Escherichia coli 97.0264, Escherichia coli E24377A, Escherichia coli B7A, Escherichia coli 3-073-06_S4_C2, Escherichia coli 2-427-07_S3_C1, Escherichia coli 2-427-07_S3_C3, Escherichia coli 2-222-05_S1_C3, Escherichia coli 2-222-05_S1_C2, Escherichia coli O121:H19 str. 2011C-3609, Escherichia coli CHS 77, Escherichia coli BIDMC 59, Escherichia coli O121:H19 str. 2010C-3794, Escherichia coli O121:H19 str. 2009C-4750, Escherichia coli O121:H19 str. 2009C-4050, Escherichia coli O39:NM str. F8704-2, Escherichia coli O121:H19 str. K5198, Escherichia coli O121:H19 str. K5269, Escherichia coli O121:H19 str. F6714, Escherichia coli O113:H21 str. 07-4224, Escherichia coli O121:H19 str. 03-3227, Escherichia coli O121:H19 str. 06-3003, Escherichia coli O121:H19 str. 06-3822, Escherichia coli O121:H19 str. 2010C-4732, Escherichia coli O121:H19 str. 2010C-4824, Escherichia coli O121:H19 str. 2010C-4966, Escherichia coli O121:H19 str. 2010EL1058, Escherichia coli O121:H19 str. 2011C-3072, Escherichia coli O121:H19 str. 2011C-3108, Escherichia coli O121:H19 str. 2011C-3537, Escherichia coli O121:H19 str. 2011C-3500, Escherichia coli O121:H19 str. 2009C-4659, Escherichia coli O121:H19 str. 2010C-3609, Escherichia coli O121:H19 str. 2010C-3840, Escherichia coli ATCC BAA-2219, Escherichia coli CE418, Escherichia coli HVH 98 (4-5799287), Escherichia coli 908541, Escherichia coli KTE13, Escherichia coli P0299917.9, Escherichia coli P0299917.8, Escherichia coli P0299917.3, Escherichia coli P0299917.10, Escherichia coli P0299438.8, Escherichia coli P0299438.7, Escherichia coli P0299438.6, Escherichia coli P0299438.5, Escherichia coli P0299438.3, Escherichia coli P0299438.11, Escherichia coli MP021561.3, Escherichia coli 2848050, Escherichia coli KTE90, Escherichia coli KTE184, Escherichia coli KTE136, Escherichia coli KTE91, Escherichia coli KTE29, Escherichia coli KTE142, Escherichia coli KTE12, Escherichia coli 3.3884, Escherichia coli 5.0959, Escherichia coli 96.154, Escherichia coli B799, Escherichia coli 3030-1, Escherichia coli STEC_94C, Escherichia coli MS 79-10, Escherichia coli TA271, Escherichia coli MS 145-7, Escherichia coli MS 107-1, Escherichia coli E110019 Bacteria UP000036210, UP000031800, UP000031953, UP000003715, UP000027906, UP000027756, UP000027656, UP000027856, UP000027650, UP000027808, UP000027115, UP000027033, UP000024257, UP000023952, UP000024107, UP000023929, UP000023828, UP000024176, UP000024098, UP000024008, UP000023843, UP000024026, UP000023859, UP000024277, UP000024022, UP000024199, UP000024163, UP000024192, UP000023956, UP000024179, UP000024005, UP000023977, UP000024273, UP000023966, UP000018835, UP000018017, UP000017537, UP000017363, UP000014123, UP000012278, UP000012420, UP000012344, UP000012415, UP000012384, UP000012257, UP000012236, UP000012327, UP000012340, UP000012385, UP000012398, UP000012353, UP000010528, UP000010550, UP000010518, UP000010558, UP000010618, UP000010577, UP000010549, UP000006026, UP000004851, UP000003674, UP000005066, UP000003029, UP000004957, UP000003901, UP000004645, UP000003691, UP000004060, UP000004350 447199622, 838785098, 838784053, 823065522, 823062637, 823008924, 822999349, 806960561, 763500881, 753923271, 752462662, 749021519, 748086418, 748053320, 748047395, 735080270, 730031528, 730004563, 729985340, 729965798, 729938562, 664696023, 652268019, 652114326, 652113271, 652059699, 652055393, 651672172, 635870667, 635795394, 607817186, 607791008, 607757857, 607696866, 607559137, 607557706, 607398335, 606993575, 606982728, 606947402, 606916667, 606850521, 606819159, 606808253, 606786113, 606782369, 606779193, 606756585, 606753478, 606528479, 606447893, 606444538, 566122044, 557929349, 554694422, 553659918, 508254402, 476993082, 476980141, 476962319, 476946876, 476930681, 476921759, 476920259, 476916311, 476904197, 476901602, 476832942, 476196111, 431712397, 431458975, 431379922, 431352407, 431292715, 431209272, 430895074, 386227843, 386207973, 386202812, 385708533, 345347502, 345346612, 342927179, 331061936, 308118710, 300527627, 192958848, 190901309 KLX67623.1, KLX66592.1, KLH86188.1, KLH83402.1, KLH31653.1, KLH22377.1, AKC13866.1, KIZ69745.1, KIO85147.1, KIO40790.1, KII02613.1, KIG93582.1, KIG63504.1, KIG57932.1, KHO57320.1, KHJ19246.1, KHI93360.1, KHI74837.1, KHI55840.1, KHI29408.1, AIF62676.1, KDZ72686.1, KDY28432.1, KDY27401.1, KDX76716.1, KDX72662.1, KDV54410.1, KDG51463.1, KDF76751.1, EZE96431.1, EZE71148.1, EZE39032.1, EZD80215.1, EZC46599.1, EZC45237.1, EZA90299.1, EZA22646.1, EZA12465.1, EYZ78859.1, EYZ50035.1, EYY87050.1, EYY57652.1, EYY47291.1, EYY26298.1, EYY22712.1, EYY19781.1, EYX98456.1, EYX95534.1, EYV83013.1, EYV05627.1, EYV02622.1, ETI79608.1, ESS93323.1, ESK00095.1, ESD77772.1, EOU27790.1, ENC79642.1, ENC67146.1, ENC50290.1, ENC35931.1, ENC20228.1, ENC11490.1, ENC10019.1, ENC06209.1, ENB94511.1, ENB92078.1, ENB32029.1, EMW16610.1, ELJ76693.1, ELH39294.1, ELG64826.1, ELG39185.1, ELF83100.1, ELF07381.1, ELC17347.1, EII55199.1, EII12478.1, EII01803.1, EIG45543.1, EGW79808.1, EGW78935.1, EGU95901.1, EGI33860.1, EFO55972.1, EFK48689.1, EDV89285.1, EDV61077.1 WP_001276878.1 fig|1116042.3.peg.4626, fig|1182694.3.peg.4280, fig|1182722.3.peg.3469, fig|754080.3.peg.4626, fig|1116055.3.peg.4977, fig|340186.3.peg.911, fig|1116043.3.peg.4690, fig|1078029.12.peg.840, fig|796392.4.peg.3779, fig|679207.4.peg.4729, fig|1116137.3.peg.4903, fig|1169318.3.peg.4213, fig|1116041.3.peg.4349, fig|550682.3.peg.2882, fig|1182719.3.peg.4527, fig|869683.3.peg.4617, fig|1116040.3.peg.4437, fig|869674.3.peg.765, fig|1116127.3.peg.4341, fig|1169332.3.peg.4232, fig|679204.3.peg.4755, fig|340184.3.peg.3766, fig|656443.3.peg.4964, fig|869676.4.peg.4922, fig|1116054.3.peg.4942, fig|1116038.3.peg.4413, fig|1078031.3.peg.2692, fig|754083.3.peg.4601, fig|1116049.3.peg.4023, fig|869684.4.peg.228, fig|1181730.3.peg.904, fig|869689.3.peg.365, fig|1116056.3.peg.5023, fig|1169367.3.peg.4447, fig|1116046.3.peg.4380, fig|1169348.3.peg.3938 626 631 yes 438123 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 379547, 439481 Aciduliprofundum boonei, Aciduliprofundum boonei T469 Archaea UP000001400 495358968, 197623769 EDY36332.1 WP_008083688.1 B5ICB3 B5ICB3_ACIB4 425 425 yes 438124 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 33029, 561177 Anaerococcus hydrogenalis, Anaerococcus hydrogenalis DSM 7454 Bacteria UP000005451 490952103, 212676533 EEB36140.1 WP_004813922.1 fig|561177.4.peg.923 431 431 yes 438125 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 164546, 977880 Cupriavidus taiwanensis, Cupriavidus taiwanensis LMG 19424 Bacteria UP000001692 501319885, 238692925, 170937868 WP_012351520.1 B2AGF3 THIC_CUPTR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5901135 fig|164546.7.peg.181 624 626 yes 438126 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1263069, 500632 Clostridium nexile CAG:348, Clostridium nexile DSM 1787 Environmental samples, Bacteria UP000018368, UP000004484 490749467, 210152272, 524481196 EEA83279.1 WP_004611775.1 fig|500632.7.peg.515 432 432 yes 438127 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 668, 388396 Aliivibrio fischeri, Vibrio fischeri MJ11 Bacteria UP000035964, UP000001857 501526144, 197315397, 238690289 ACH64844.1 WP_012532655.1 B5FF66 THIC_VIBFM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7069480 fig|388396.11.peg.33 640 644 yes 438128 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 285530, 463191 Streptomyces sviceus, Streptomyces sviceus ATCC 29083 Bacteria UP000002785 494625290, 197716385 EDY60419.1 WP_007383234.1 fig|463191.3.peg.6751 594 599 yes 438129 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 777, 434923 Coxiella burnetii, Coxiella burnetii CbuG_Q212 Bacteria UP000033654, UP000007729 501565928, 212011575, 226695520 ACJ18956.1 WP_012570376.1 B6J1X8 THIC_COXB2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5610892 fig|434923.3.peg.1681 546 554 yes 438130 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 1194155, 1029977, 1079469, 1029982, 702982, 1124964, 439846 Salmonella enterica, Salmonella enterica subsp. enterica serovar London str. CFSAN001081, Salmonella enterica subsp. enterica serovar Paratyphi B str. SARA42, Salmonella enterica subsp. enterica serovar Saintpaul str. JO2008, Salmonella enterica subsp. enterica serovar Tallahassee str. 0012, Salmonella enterica subsp. enterica serovar Saintpaul str. SARA26, Salmonella enterica subsp. enterica serovar Saintpaul str. 9712, Salmonella enterica subsp. enterica serovar Saintpaul str. SARA23 Bacteria UP000054489, UP000017434, UP000017487, UP000017613, UP000017478, UP000017560, UP000017382, UP000002994 446030557, 554422843, 554133920, 554114089, 554083463, 554031620, 553490466, 197243581 ESJ49000.1, ESF74338.1, ESF55267.1, ESF26697.1, ESE77754.1, ESC14416.1, EDY26201.1 WP_000108412.1 fig|439846.4.peg.16, fig|1328332.3.peg.273 626 631 yes 438131 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 310298, 470145 Bacteroides coprocola, Bacteroides coprocola DSM 17136 Bacteria UP000003146 494842231, 189433406 EDV02391.1 WP_007568331.1 fig|470145.6.peg.1733 564 564 yes 438132 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 483218 Bacteroides pectinophilus ATCC 43243 Bacteria UP000003136 217992120 EEC58124.1 438 439 yes 438133 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 59201, 1192689, 1192688, 687860, 687915, 909945, 439851, 98360 Salmonella enterica, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Dublin str. DG22, Salmonella enterica subsp. enterica serovar Dublin str. UC16, Salmonella enterica subsp. enterica serovar Dublin str. HWS51, Salmonella enterica subsp. enterica serovar Dublin str. SL1438, Salmonella enterica subsp. enterica serovar Dublin str. SD3246, Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853, Salmonella enterica subsp. enterica serovar Dublin Bacteria UP000054489, UP000033855, UP000014552, UP000013259, UP000011530, UP000011583, UP000002794, UP000008322, UP000036813 446030569, 735748559, 735741671, 735741641, 514614872, 471373963, 444849997, 444846787, 326625873, 197938663, 661558856, 238690354 KHP18923.1, KHP12081.1, KHP12052.1, EPI74555.1, EMR51804.1, ELX75104.1, ELX71941.1, EGE32218.1, ACH75996.1 WP_000108424.1 B5FQK9 THIC_SALDC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7299593 fig|909945.3.peg.4440, fig|439851.5.peg.4500, fig|687915.3.peg.3304, fig|1192688.3.peg.2853, fig|687860.3.peg.3672 626 631 yes 438134 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 89152, 500633 Clostridium hiranonis, Clostridium hiranonis DSM 13275 Bacteria UP000003178 493484530, 210154940 EEA85946.1 WP_006439347.1 fig|500633.7.peg.605 433 435 yes 438135 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 100226, 1902 Streptomyces coelicolor A3(2), Streptomyces coelicolor Bacteria UP000001973 UP000001973 21222334, 499339607, 7388312, 5457278 NP_628113.1, WP_011029315.1 Q9X9U0 THIC_STRCO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 244205 fig|100226.1.peg.3885 601 612 yes 438136 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 1194159, 685040, 909947, 550538 Salmonella enterica, Salmonella enterica subsp. enterica serovar Stanleyville str. CFSAN000624, Salmonella enterica subsp. enterica serovar Gallinarum str. 9184, Salmonella enterica subsp. enterica serovar Gallinarum str. SG9, Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91 Bacteria UP000054489, UP000017525, UP000011660, UP000005751, UP000008321 446030575, 554472534, 444846572, 326629566, 238690531, 205274215 ESJ90204.1, ELX71736.1, EGE35909.1 WP_000108430.1 B5RFJ0 THIC_SALG2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5802532 fig|550538.3.peg.3656, fig|685040.3.peg.3614, fig|909947.3.peg.3694 626 631 yes 438137 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 439496 Rhodobacterales bacterium Y4I Bacteria UP000005133 495832469, 206687478 EDZ47960.1 WP_008557048.1 fig|439496.3.peg.113 596 604 yes 438138 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 225194, 404380 Geobacter bemidjiensis, Geobacter bemidjiensis Bem Bacteria UP000008825 501523952, 197089185 ACH40456.1 WP_012531889.1 fig|404380.3.peg.3389 437 437 yes 438139 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1901, 443255 Streptomyces clavuligerus, Streptomyces clavuligerus ATCC 27064 Bacteria UP000002357 490054244, 294326293, 197705164 EFG07936.1, EDY50976.1 WP_003956556.1 590 592 yes 438140 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 62322, 407976 Shewanella baltica, Shewanella baltica OS223 Bacteria UP000002507 501583255, 217498335 ACK46528.1 WP_012587568.1 fig|407976.7.peg.2092 655 707 yes 438141 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1096, 331678 Chlorobium phaeobacteroides, Chlorobium phaeobacteroides BS1 Bacteria UP000001228 501450893, 189495306, 238692291 ACE03854.1 WP_012474342.1 B3EPH6 THIC_CHLPB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6945031 fig|331678.4.peg.982 561 563 yes 438142 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 521006 Neisseria gonorrhoeae NCCP11945 Bacteria UP000002564 193934975 ACF30799.1 fig|521006.8.peg.2371 625 671 yes 438143 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 837, 431947 Porphyromonas gingivalis, Porphyromonas gingivalis ATCC 33277 Bacteria UP000028798, UP000008842 501432630, 672596053, 238691457, 188593704 AIJ35029.1 WP_012457290.1 B2RH34 THIC_PORG3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5606761 fig|431947.6.peg.154 587 587 yes 438144 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 338565, 465817 Erwinia tasmaniensis, Erwinia tasmaniensis Et1/99 Bacteria UP000001726 501408372, 188027370 WP_012439938.1 fig|465817.9.peg.218 631 644 yes 438145 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 419541 Leptospirillum sp. Group II '5-way CG' Bacteria 206602224 EDZ38706.1 462 468 yes 438146 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 29449, 491916 Rhizobium etli, Rhizobium etli CIAT 652 Bacteria UP000008817 501466354, 190700244 ACE94326.1 WP_012489799.1 fig|491916.4.peg.251 601 610 yes 438147 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 259354, 439235 Desulfatibacillum alkenivorans, Desulfatibacillum alkenivorans AK-01 Bacteria UP000000739 501639817, 218759680 ACL02146.1 WP_012609586.1 fig|439235.3.peg.470 438 438 yes 438148 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 86662, 526976, 1220585 Bacillus weihenstephanensis, Bacillus cereus BDRD-ST196, Bacillus weihenstephanensis NBRC 101238 = DSM 11821 Bacteria UP000030313, UP000002295, UP000018891 487961477, 719646743, 228647425, 569023706 AIW87157.1, EEL03502.1 WP_002034781.1 fig|526976.3.peg.1865 586 586 yes 438149 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 79967, 644651, 634499 Erwinia pyrifoliae, Erwinia pyrifoliae DSM 12163, Erwinia pyrifoliae Ep1/96 Bacteria UP000008690, UP000007061 501908791, 283476736, 224962564 WP_012666639.1 fig|644651.3.peg.254, fig|634499.3.peg.264 631 644 yes 438150 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 564, 981367, 585054 Escherichia fergusonii, Escherichia fergusonii ECD227, Escherichia fergusonii ATCC 35469 Bacteria UP000033773, UP000010293, UP000000745 447199637, 803344560, 325499274, 226695852, 218358563 KKA85173.1, EGC97133.1 WP_001276893.1 B7LUK8 THIC_ESCF3 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} fig|981367.3.peg.3689, fig|585054.5.peg.3622 626 631 yes 438151 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 64104, 527000 Bacillus pseudomycoides, Bacillus pseudomycoides DSM 12442 Bacteria UP000001378 493026258, 228764683 EEM13482.1 WP_006097487.1 fig|527000.3.peg.1150 586 586 yes 438152 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 1452729, 1430, 718222, 1217737, 1218175, 1053220, 718223, 527020, 527026 Bacillus thuringiensis HD1002, Bacillus thuringiensis serovar israelensis, Bacillus cereus TIAC219, Bacillus thuringiensis HD-789, Bacillus thuringiensis HD-771, Bacillus cereus MSX-A1, Bacillus cereus VD022, Bacillus thuringiensis IBL 4222, Bacillus thuringiensis serovar sotto str. T04001 Bacteria UP000031903, UP000021329, UP000014060, UP000005257, UP000005259, UP000006602, UP000006991, UP000006648, UP000001375 446737221, 755732643, 591113437, 500621178, 401876898, 401791828, 401193031, 401076689, 228855967, 228791311 AJH03766.1, EXL34175.1, EOQ61237.1, AFQ29065.1, AFQ17867.1, EJR00039.1, EJP85040.1, EEN00507.1, EEM38918.1 WP_000814477.1 fig|718223.3.peg.4988, fig|527020.3.peg.2476, fig|1217737.3.peg.4928, fig|1218175.3.peg.4473, fig|1053220.3.peg.5351, fig|527026.3.peg.2629, fig|339854.4.peg.1389, fig|718222.3.peg.4186 586 586 yes 438153 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526968 Bacillus cereus, Bacillus cereus R309803 Bacteria UP000036076, UP000006816 446737197, 228619284 EEK76175.1 WP_000814453.1 fig|526968.3.peg.5449 586 586 yes 438154 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526979 Bacillus cereus, Bacillus cereus 95/8201 Bacteria UP000036076, UP000002293 446737232, 755999997, 753524507, 228658709 AJK36224.1, AJH61958.1, EEL14369.1 WP_000814488.1 fig|526979.3.peg.5621 586 586 yes 438155 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2173, 483214 Methanobrevibacter smithii, Methanobrevibacter smithii DSM 2375 Archaea 490135984, 222435253 EEE42418.1 WP_004036344.1 B9AG28 B9AG28_METSM 432 432 yes 438156 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 487, 122587 Neisseria meningitidis, Neisseria meningitidis Z2491 Bacteria UP000050419, UP000000626 499289807, 121051395, 24638285 WP_010981073.1 Q9JWF3 THIC_NEIMA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 141578 fig|122587.5.peg.454, fig|122587.1.peg.371 625 633 yes 438157 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 427926, 555088 Dethiobacter alkaliphilus, Dethiobacter alkaliphilus AHT 1 Bacteria UP000006443 495789602, 225170233 EEG79028.1 WP_008514181.1 fig|555088.4.peg.293 431 432 yes 438158 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 387661, 999419, 537006 Parabacteroides johnsonii, Parabacteroides johnsonii CL02T12C29, Parabacteroides johnsonii DSM 18315 Bacteria UP000001218, UP000005510 495423428, 409214891, 218224500 EKN07900.1, EEC97150.1 WP_008148125.1 fig|999419.3.peg.3082, fig|537006.5.peg.1209 567 568 yes 438159 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2173, 483214 Methanobrevibacter smithii, Methanobrevibacter smithii DSM 2375 Archaea 490136149, 222435365 EEE42530.1 WP_004036509.1 B9AGE0 B9AGE0_METSM 423 424 yes 438160 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 87883, 513053, 513052 Burkholderia multivorans, Burkholderia multivorans CGD2M, Burkholderia multivorans CGD2 Bacteria UP000066418, UP000003198, UP000004535 493452246, 221178717, 221172181 EEE11125.1, EEE04622.1 WP_006407523.1 fig|513052.3.peg.4985, fig|513053.3.peg.5125 642 643 yes 438161 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 281920, 596327 Porphyromonas uenonis, Porphyromonas uenonis 60-3 Bacteria UP000003303 494607247, 228307719 EEK16695.1 WP_007365494.1 fig|596327.3.peg.987 590 590 yes 438162 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 380, 394 Sinorhizobium fredii, Rhizobium sp. NGR234 Bacteria UP000001054 502084755, 227818540, 227337539 ACP21758.1 WP_012706357.1, YP_002822511.1 6786896 fig|394.7.peg.741 598 610 yes 438163 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 585397 Escherichia coli ED1a Bacteria UP000000748 254784164, 218429839 B7MRC0 THIC_ECO81 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5898414 fig|585397.7.peg.4687 626 631 yes 438164 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 395961 Cyanothece sp. PCC 7425 Bacteria UP000002511 501732796, 219865209, 254784159 ACL45548.1 WP_012628611.1 B8HNW1 THIC_CYAP4 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5555926 fig|395961.4.peg.3179 456 458 yes 438165 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1203471, 316067 Geobacter daltonii, Geobacter sp. FRC-32 Bacteria UP000007721 501811843, 221562938 ACM18910.1 WP_012645639.1 fig|316067.3.peg.560 431 435 yes 438166 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 43080, 427317 Sulfolobus islandicus, Sulfolobus islandicus M.14.25 Archaea UP000001350 502106191, 227459054, 259517507 ACP37740.1 WP_012711006.1 C3MX60 THIC_SULIM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7255857 432 433 yes 438167 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 197, 192222, 32022, 1385724, 1385722, 1385721, 1385723, 1385720, 1357994, 1383068, 1380767, 1380768, 889235, 889214, 889245, 691337, 691336, 360110, 360111, 1211776 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni, Campylobacter jejuni subsp. jejuni NCTC 11168-rNRC, Campylobacter jejuni subsp. jejuni NCTC 11168-mfK12E5, Campylobacter jejuni subsp. jejuni NCTC 11168-mcK12E5, Campylobacter jejuni subsp. jejuni NCTC 11168-Kf1, Campylobacter jejuni subsp. jejuni NCTC 11168-K12E5, Campylobacter jejuni subsp. jejuni 00-2425, Campylobacter jejuni subsp. jejuni 00-2544, Campylobacter jejuni subsp. jejuni 00-2426, Campylobacter jejuni subsp. jejuni 00-2538, Campylobacter jejuni subsp. jejuni 1928, Campylobacter jejuni subsp. jejuni 110-21, Campylobacter jejuni subsp. jejuni LMG 9879, Campylobacter jejuni subsp. jejuni 305, Campylobacter jejuni subsp. jejuni DFVF1099, Campylobacter jejuni subsp. jejuni 84-25, Campylobacter jejuni subsp. jejuni CF93-6, Campylobacter jejuni subsp. jejuni NCTC 11168-BN148 Bacteria UP000065538, UP000000799, UP000032540, UP000031757, UP000031762, UP000031753, UP000031754, UP000031780, UP000016701, UP000016467, UP000016468, UP000016466, UP000003876, UP000005138, UP000005043, UP000004891, UP000005980, UP000005531, UP000004120, UP000003927 488947546, 218562108, 756103491, 756090213, 756014564, 736041926, 589078374, 589076709, 589075043, 589073376, 589071710, 543885497, 542824371, 542820555, 542816993, 380669497, 380652445, 380616279, 315930010, 315928219, 88190811, 85840572, 401780883, 112359814, 29337150 AJK84260.1, AJK82426.1, AJK72339.1, AJA54570.1, AHK58411.1, AHK56747.1, AHK55082.1, AHK53416.1, AHK51751.1, AGV56283.1, AGV47338.1, AGV50767.1, AGV49100.1, EIB84781.1, EIB68926.1, EIB35488.1, EFV09153.1, EFV07536.1, EAQ94784.1, EAQ57829.1 WP_002858621.1, YP_002343887.1 Q9PI55 THIC_CAMJE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 46369, 2733604, 2751293 fig|1111076.3.peg.476, fig|360110.3.peg.1726, fig|889235.3.peg.1161, fig|1111073.3.peg.1409, fig|1111074.3.peg.882, fig|1111072.3.peg.442, fig|889214.3.peg.319, fig|192222.1.peg.418, fig|1211776.3.peg.440, fig|360111.3.peg.756, fig|691337.3.peg.668, fig|1111075.3.peg.302, fig|889245.3.peg.573, fig|691336.3.peg.265 430 430 yes 438168 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 53443, 476272, 1263061 Blautia hydrogenotrophica, Blautia hydrogenotrophica DSM 10507, Blautia hydrogenotrophica CAG:147 Bacteria, Environmental samples UP000003100, UP000018163 492751677, 225038398, 524855648 EEG48644.1 WP_005949828.1 fig|476272.5.peg.2064 433 433 yes 438169 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526980 Bacillus cereus, Bacillus cereus ATCC 10876 Bacteria UP000036076, UP000001484 446737224, 674826455, 228590005 KFL78999.1, EEK47877.1 WP_000814480.1 fig|526980.3.peg.348 586 586 yes 438170 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 49338, 272564 Desulfitobacterium hafniense, Desulfitobacterium hafniense DCB-2 Bacteria UP000054623, UP000007726 506424356, 219538807, 254784160 ACL20546.1 WP_015944075.1 B8FUD2 THIC_DESHD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1225690, 6822492 fig|272564.6.peg.2620 428 432 yes 438171 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526992 Bacillus cereus, Bacillus cereus AH1271 Bacteria UP000036076, UP000001354 446737191, 228728392 EEL79413.1 WP_000814447.1 fig|526992.3.peg.2882 586 586 yes 438172 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 408, 440085, 661410 Methylobacterium extorquens, Methylobacterium chloromethanicum CM4, Methylobacterium extorquens DM4 Bacteria UP000002385, UP000008070 506302422, 218522169, 254268008 ACK82754.1 WP_015822197.1 fig|440085.6.peg.1827, fig|661410.3.peg.2116 625 630 yes 438173 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 469, 525244 Acinetobacter sp. ATCC 27244 Bacteria UP000012347 496228225, 226837477 EEH69860.1 WP_008942260.1 fig|525244.5.peg.2139, fig|1221299.3.peg.2006 626 631 yes 438174 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 399795 Comamonas testosteroni KF-1 Bacteria UP000003039 220710835 EED66203.1 fig|399795.3.peg.1173, fig|1111078.3.peg.4181 625 654 yes 438175 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 358681 Brevibacillus brevis NBRC 100599 Bacteria UP000001877 226096179 fig|358681.3.peg.3610 590 593 yes 438176 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 310783, 546414 Deinococcus deserti, Deinococcus deserti VCD115 Bacteria UP000002208 502012538, 226317284 ACO45280.1 WP_012692403.1 fig|546414.3.peg.506 602 613 yes 438177 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 309805, 123214 Persephonella marina, Persephonella marina EX-H1 Bacteria UP000001366 506379270, 225646699 ACO04885.1 WP_015898989.1 fig|123214.3.peg.836 452 455 yes 438178 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 1322345, 316435, 1444159, 1444131, 1444271, 1444214, 1444242, 1280974, 1281020, 1389417, 1281023, 1281246, 1269008, 1268990, 1268980, 1281257, 1281093, 1281092, 1281090, 1281089, 1281279, 1281271, 1281267, 1281268, 1281264, 1281262, 1281251, 1281244, 1281232, 1281231, 1281230, 1281226, 1281224, 1281222, 1281220, 1281217, 1281207, 1281205, 1281203, 1281202, 1281198, 1281199, 1281197, 1281186, 1281180, 1281173, 1281164, 1281161, 1281160, 1281151, 1281146, 1281145, 1281143, 1281139, 1281134, 1281131, 1281120, 1281102, 1281099, 1281086, 1281082, 1281077, 1281075, 1281065, 1281057, 1281054, 1281053, 1281050, 1281045, 1281039, 1281032, 1281031, 1281029, 1281026, 1281015, 1281013, 1281009, 1281006, 1281004, 1280999, 1280996, 1280990, 1280989, 1280987, 1280978, 1280971, 1280967, 1280966, 1280962, 1181772, 1169371, 1169370, 1169400, 1169398, 1169395, 1169393, 1169387, 1169381, 1181769, 1181764, 1181755, 1182721, 1182670, 1182692, 1182674, 1182667, 1182660, 1181776, 1181766, 1181760, 1181747, 1181734, 1181733, 1169356, 749541, 655817, 749528, 749546, 525281, 199310 Escherichia coli, Escherichia coli ATCC 25922, Escherichia coli Nissle 1917, Escherichia coli 8-415-05_S3_C2, Escherichia coli 8-415-05_S3_C1, Escherichia coli 8-415-05_S4_C3, Escherichia coli 8-415-05_S4_C1, Escherichia coli 8-415-05_S4_C2, Escherichia coli HVH 23 (4-6066488), Escherichia coli HVH 83 (4-2051087), Escherichia coli LAU-EC6, Escherichia coli HVH 86 (4-7026218), Escherichia coli UMEA 3342-1, Escherichia coli A25922R, Escherichia coli 907892, Escherichia coli 907391, Escherichia coli UMEA 3652-1, Escherichia coli HVH 160 (4-5695937), Escherichia coli HVH 159 (4-5818141), Escherichia coli HVH 157 (4-3406229), Escherichia coli HVH 156 (4-3206505), Escherichia coli UMEA 4207-1, Escherichia coli UMEA 3821-1, Escherichia coli UMEA 3705-1, Escherichia coli UMEA 3707-1, Escherichia coli UMEA 3694-1, Escherichia coli UMEA 3687-1, Escherichia coli UMEA 3490-1, Escherichia coli UMEA 3337-1, Escherichia coli UMEA 3268-1, Escherichia coli UMEA 3264-1, Escherichia coli UMEA 3257-1, Escherichia coli UMEA 3233-1, Escherichia coli UMEA 3222-1, Escherichia coli UMEA 3220-1, Escherichia coli UMEA 3216-1, Escherichia coli UMEA 3208-1, Escherichia coli UMEA 3178-1, Escherichia coli UMEA 3175-1, Escherichia coli UMEA 3173-1, Escherichia coli UMEA 3172-1, Escherichia coli UMEA 3160-1, Escherichia coli UMEA 3161-1, Escherichia coli UMEA 3159-1, Escherichia coli UMEA 3121-1, Escherichia coli UMEA 3087-1, Escherichia coli UMEA 3014-1, Escherichia coli KOEGE 61 (174a), Escherichia coli KOEGE 44 (106a), Escherichia coli KOEGE 43 (105a), Escherichia coli HVH 227 (4-2277670), Escherichia coli HVH 220 (4-5876842), Escherichia coli HVH 218 (4-4500903), Escherichia coli HVH 216 (4-3042952), Escherichia coli HVH 212 (3-9305343), Escherichia coli HVH 207 (4-3113221), Escherichia coli HVH 204 (4-3112802), Escherichia coli HVH 193 (4-3331423), Escherichia coli HVH 172 (4-3248542), Escherichia coli HVH 169 (4-1075578), Escherichia coli HVH 153 (3-9344314), Escherichia coli HVH 149 (4-4451880), Escherichia coli HVH 144 (4-4451937), Escherichia coli HVH 142 (4-5627451), Escherichia coli HVH 132 (4-6876862), Escherichia coli HVH 120 (4-6978681), Escherichia coli HVH 117 (4-6857191), Escherichia coli HVH 116 (4-6879942), Escherichia coli HVH 114 (4-7037740), Escherichia coli HVH 109 (4-6977162), Escherichia coli HVH 103 (4-5904188), Escherichia coli HVH 96 (4-5934869), Escherichia coli HVH 95 (4-6074464), Escherichia coli HVH 92 (4-5930790), Escherichia coli HVH 89 (4-5885604), Escherichia coli HVH 77 (4-2605759), Escherichia coli HVH 74 (4-1034782), Escherichia coli HVH 68 (4-0888028), Escherichia coli HVH 61 (4-2736020), Escherichia coli HVH 58 (4-2839709), Escherichia coli HVH 51 (4-2172526), Escherichia coli HVH 46 (4-2758776), Escherichia coli HVH 40 (4-1219782), Escherichia coli HVH 39 (4-2679949), Escherichia coli HVH 37 (4-2773848), Escherichia coli HVH 27 (4-7449267), Escherichia coli HVH 20 (4-5865042), Escherichia coli HVH 16 (4-7649002), Escherichia coli HVH 13 (4-7634056), Escherichia coli HVH 7 (4-7315031), Escherichia coli KTE226, Escherichia coli KTE99, Escherichia coli KTE97, Escherichia coli KTE174, Escherichia coli KTE167, Escherichia coli KTE160, Escherichia coli KTE153, Escherichia coli KTE137, Escherichia coli KTE124, Escherichia coli KTE223, Escherichia coli KTE218, Escherichia coli KTE209, Escherichia coli KTE141, Escherichia coli KTE63, Escherichia coli KTE87, Escherichia coli KTE67, Escherichia coli KTE60, Escherichia coli KTE53, Escherichia coli KTE230, Escherichia coli KTE220, Escherichia coli KTE214, Escherichia coli KTE201, Escherichia coli KTE188, Escherichia coli KTE187, Escherichia coli KTE39, Escherichia coli MS 153-1, Escherichia coli ABU 83972, Escherichia coli MS 45-1, Escherichia coli MS 185-1, Escherichia coli 83972, Escherichia coli CFT073 Bacteria UP000036210, UP000028955, UP000011176, UP000028096, UP000027784, UP000027801, UP000027894, UP000028103, UP000018710, UP000018687, UP000018757, UP000017745, UP000017321, UP000017580, UP000017445, UP000017482, UP000016339, UP000016330, UP000016116, UP000016251, UP000016346, UP000016111, UP000016323, UP000016293, UP000016137, UP000016121, UP000016264, UP000016410, UP000016297, UP000016051, UP000016265, UP000016356, UP000016036, UP000016047, UP000016393, UP000016113, UP000016123, UP000016241, UP000016367, UP000016032, UP000016343, UP000016072, UP000016135, UP000016326, UP000016385, UP000016093, UP000016258, UP000016102, UP000015996, UP000016247, UP000015987, UP000016394, UP000016279, UP000016097, UP000016240, UP000016001, UP000016408, UP000016103, UP000016089, UP000016387, UP000016100, UP000016273, UP000016353, UP000016427, UP000016086, UP000016124, UP000016011, UP000016080, UP000016050, UP000016327, UP000016366, UP000016082, UP000016252, UP000017042, UP000016298, UP000016281, UP000016261, UP000016007, UP000015986, UP000016149, UP000016021, UP000016389, UP000016380, UP000016015, UP000016079, UP000016143, UP000016350, UP000016132, UP000016109, UP000016030, UP000014121, UP000010539, UP000010688, UP000010680, UP000010665, UP000010535, UP000010584, UP000010709, UP000010517, UP000010689, UP000010634, UP000010572, UP000010684, UP000010696, UP000010541, UP000010664, UP000010529, UP000010513, UP000010641, UP000010712, UP000010603, UP000010698, UP000010645, UP000010707, UP000010495, UP000004053, UP000002253, UP000003658, UP000003757, UP000005329, UP000001410 485663902, 838760349, 838757860, 838727242, 674299450, 660664129, 660661955, 660514279, 660279264, 660246007, 658682873, 658661725, 658661034, 597619373, 597613782, 565502989, 565501810, 564919682, 556127040, 554719961, 553719403, 553620940, 553579299, 537731488, 535982113, 535971826, 535963672, 535963586, 535911788, 535872350, 535854574, 535853576, 535839747, 535832796, 535786638, 535762422, 535737367, 535729257, 535728523, 535716666, 535702679, 535692665, 535681331, 535671617, 535615184, 535602747, 535597815, 535590593, 535577461, 535577415, 535568298, 535536294, 535507854, 535473032, 535421681, 535412342, 535408397, 535377838, 535359833, 535350910, 535347513, 535323208, 535309040, 535293941, 535241677, 535161526, 535147835, 535099593, 535088302, 535067069, 535065269, 535013455, 534976325, 534962701, 534954046, 534935061, 534915124, 534895869, 534882116, 534872095, 534870042, 534850472, 534813372, 534793132, 534777591, 534763576, 534753641, 534734787, 534727016, 534693570, 534682701, 534677202, 534635597, 534600671, 534585807, 534583774, 534568997, 508535797, 507478607, 431730724, 431727648, 431666413, 431654408, 431639190, 431629576, 431599720, 431564902, 431520076, 431513222, 431484806, 431391724, 431333889, 431186301, 431143620, 431125077, 431096377, 431047000, 431034481, 431030164, 430987352, 430959308, 430958204, 430931701, 315294349, 307556137, 300409452, 300300393, 227837550, 441711362, 29337056 KLX43243.1, KLX40798.1, KLX10508.1, AIL14342.1, KEP03657.1, KEP01486.1, AID81170.1, KEN69377.1, KEN36853.1, KEJ26222.1, KEJ06032.1, KEJ05362.1, EYB64896.1, EYB59488.1, ETF14907.1, ETF13749.1, ETE14944.1, ESP15548.1, ESK25276.1, ESE34356.1, ESD40614.1, ESD00825.1, ERF51901.1, ERA81889.1, ERA71737.1, ERA63670.1, ERA63588.1, ERA42562.1, ERA03975.1, EQZ86560.1, EQZ85582.1, EQZ71939.1, EQZ65118.1, EQZ19830.1, EQY96005.1, EQY71679.1, EQY63747.1, EQY63075.1, EQY51379.1, EQY37698.1, EQY27897.1, EQY16769.1, EQY07285.1, EQX51990.1, EQX39813.1, EQX35017.1, EQX27885.1, EQX14943.1, EQX14899.1, EQX05911.1, EQW74551.1, EQW46719.1, EQW12995.1, EQV62493.1, EQV53583.1, EQV49688.1, EQV19765.1, EQV02132.1, EQU93327.1, EQU89969.1, EQU65973.1, EQU51913.1, EQU36963.1, EQT85288.1, EQT06202.1, EQS92734.1, EQS45823.1, EQS34932.1, EQS13749.1, EQS11960.1, EQR60993.1, EQR24743.1, EQR11278.1, EQR02796.1, EQQ84104.1, EQQ64537.1, EQQ45717.1, EQQ32259.1, EQQ22463.1, EQQ20444.1, EQQ01193.1, EQP64990.1, EQP45482.1, EQP30134.1, EQP16334.1, EQP06505.1, EQO87997.1, EQO80312.1, EQO49297.1, EQO38571.1, EQO33203.1, EQN92182.1, EQN58477.1, EQN44305.1, EQN41693.1, EQN28110.1, EOX04190.1, EOR53275.1, ELJ94284.1, ELJ91395.1, ELJ33051.1, ELJ21464.1, ELJ07057.1, ELI97937.1, ELI69424.1, ELI38048.1, ELH97504.1, ELH91306.1, ELH64478.1, ELG75334.1, ELG21072.1, ELE85863.1, ELE45341.1, ELE27508.1, ELE01862.1, ELD57090.1, ELD46416.1, ELD43179.1, ELD03891.1, ELC77638.1, ELC76800.1, ELC52140.1, EFU53700.1, ADN48912.1, EFJ92990.1, EFJ56778.1, EEJ48016.1 WP_001305321.1 Q8FB77 THIC_ECOL6 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 306687 fig|1322345.3.peg.1378, fig|1169398.3.peg.4116, fig|1182674.3.peg.426, fig|525281.3.peg.4730, fig|749528.3.peg.1798, fig|1169393.3.peg.4270, fig|1258580.3.peg.2206, fig|316435.3.peg.3938, fig|1181769.3.peg.20, fig|749546.3.peg.1675, fig|1182670.3.peg.145, fig|1258567.3.peg.2171, fig|1169381.3.peg.4447, fig|1181760.3.peg.415, fig|1182667.3.peg.4830, fig|749541.3.peg.1029, fig|1169370.3.peg.4078, fig|1181747.3.peg.20, fig|1181734.3.peg.4858, fig|199310.4.peg.4650, fig|1169395.3.peg.4276, fig|1181766.3.peg.4122, fig|1169400.3.peg.4441, fig|1181755.3.peg.2186, fig|885275.3.peg.4343, fig|1169387.3.peg.4309, fig|1169356.3.peg.5012, fig|1182692.3.peg.4878, fig|885276.3.peg.4348, fig|1181776.3.peg.4783, fig|1169371.3.peg.4324, fig|1182721.3.peg.4707, fig|199310.1.peg.4848, fig|1181772.3.peg.4526, fig|655817.3.peg.4700, fig|1181764.3.peg.305, fig|1163386.3.peg.1986, fig|1182660.3.peg.5053, fig|1181733.3.peg.19 626 631 yes 438179 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1203471, 316067 Geobacter daltonii, Geobacter sp. FRC-32 Bacteria UP000007721 501814307, 221563805 ACM19777.1 WP_012646506.1 fig|316067.3.peg.1456 436 436 yes 438180 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 227290, 359, 311403 Agrobacterium rhizogenes, Agrobacterium radiobacter K84 Bacteria UP000027865, UP000001600 501827007, 653176320, 221725823, 254784149 KEA03564.1, ACM28912.1 WP_012649274.1 B9JMY1 THIC_AGRRK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5482144 fig|311403.8.peg.332 601 608 yes 438181 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526974 Bacillus cereus, Bacillus cereus BDRD-ST24 Bacteria UP000036076, UP000006656 446737227, 228635770 EEK92257.1 WP_000814483.1 fig|526974.3.peg.207 586 586 yes 438182 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 168471, 557598 Laribacter hongkongensis, Laribacter hongkongensis HLHK9 Bacteria UP000002010 502026827, 226716502 ACO75640.1 WP_012698104.1 fig|557598.3.peg.2424 632 634 yes 438183 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 391586 Vibrio parahaemolyticus 16 Bacteria UP000002775 491616909, 219548810 EED25812.1 WP_005474464.1 fig|391586.4.peg.2994 640 646 yes 438184 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526971 Bacillus cereus, Bacillus cereus MM3 Bacteria UP000036076, UP000001751 446737192, 228607629 EEK64953.1 WP_000814448.1 fig|526971.3.peg.150 586 586 yes 438185 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 259354, 439235 Desulfatibacillum alkenivorans, Desulfatibacillum alkenivorans AK-01 Bacteria UP000000739 501641138, 218760340 ACL02806.1 WP_012610244.1 fig|439235.3.peg.1167 429 429 yes 438186 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 405212, 543302 Alicyclobacillus acidocaldarius, Alicyclobacillus acidocaldarius LAA1 Bacteria UP000035012 495615088, 218239930 EED07117.1 WP_008339667.1 fig|543302.3.peg.1729 572 573 yes 438187 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 161493, 455488 Anaeromyxobacter dehalogenans, Anaeromyxobacter dehalogenans 2CP-1 Bacteria UP000007089 501750143, 219955258, 254784151 ACL65642.1 WP_012633476.1 B8JAC3 THIC_ANAD2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7368239 fig|455488.3.peg.2341 457 463 yes 438188 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 561, 585056, 562, 1438688, 1269000, 1268999, 1268992, 1268993, 1268987, 1268986, 1281088, 1281169, 1281165, 1281166, 1281149, 1281142, 1281135, 1281133, 1281116, 1281110, 1281103, 1281098, 1281096, 1281084, 1281078, 1281073, 1281066, 1281068, 1281067, 1281064, 1281059, 1281056, 1281049, 1281046, 1281042, 1281025, 1281022, 1281010, 1281007, 1280995, 1280980, 1280973, 1280964, 1181771, 1169315, 1279005, 1182737, 1182717, 1182714, 1182675, 1181746, 1169323, 1169369, 1169363, 1169402, 1169383, 1169380, 1169373, 1181736, 1182731, 1182720, 1182661, 1182708, 1182689, 1182687, 1182673, 1181779, 1181774, 1181759, 1181754, 1181750, 1181727, 1169345, 1169324, 752787, 754085, 656444, 749549, 656379, 656380 Escherichia coli UMN026, Escherichia coli, Escherichia coli MGH 58, Escherichia coli 908616, Escherichia coli 908585, Escherichia coli 908521, Escherichia coli 908522, Escherichia coli 907715, Escherichia coli 907713, Escherichia coli HVH 155 (4-4509048), Escherichia coli KOEGE 73 (195a), Escherichia coli KOEGE 62 (175a), Escherichia coli KOEGE 68 (182a), Escherichia coli HVH 223 (4-2976528), Escherichia coli HVH 215 (4-3008371), Escherichia coli HVH 208 (4-3112292), Escherichia coli HVH 206 (4-3128229), Escherichia coli HVH 189 (4-3220125), Escherichia coli HVH 183 (4-3205932), Escherichia coli HVH 173 (3-9175482), Escherichia coli HVH 167 (4-6073565), Escherichia coli HVH 163 (4-4697553), Escherichia coli HVH 151 (4-5755573), Escherichia coli HVH 145 (4-5672112), Escherichia coli HVH 140 (4-5894387), Escherichia coli HVH 133 (4-4466519), Escherichia coli HVH 135 (4-4449320), Escherichia coli HVH 134 (4-6073441), Escherichia coli HVH 130 (4-7036876), Escherichia coli HVH 122 (4-6851606), Escherichia coli HVH 119 (4-6879578), Escherichia coli HVH 113 (4-7535473), Escherichia coli HVH 110 (4-6978754), Escherichia coli HVH 106 (4-6881831), Escherichia coli HVH 88 (4-5854636), Escherichia coli HVH 85 (4-0792144), Escherichia coli HVH 69 (4-2837072), Escherichia coli HVH 63 (4-2542528), Escherichia coli HVH 45 (4-3129918), Escherichia coli HVH 29 (4-3418073), Escherichia coli HVH 22 (4-2258986), Escherichia coli HVH 10 (4-6832164), Escherichia coli KTE225, Escherichia coli KTE1, Escherichia coli KTE172, Escherichia coli KTE170, Escherichia coli KTE134, Escherichia coli KTE127, Escherichia coli KTE68, Escherichia coli KTE200, Escherichia coli KTE231, Escherichia coli KTE95, Escherichia coli KTE82, Escherichia coli KTE177, Escherichia coli KTE128, Escherichia coli KTE122, Escherichia coli KTE105, Escherichia coli KTE190, Escherichia coli KTE158, Escherichia coli KTE140, Escherichia coli KTE54, Escherichia coli KTE116, Escherichia coli KTE83, Escherichia coli KTE80, Escherichia coli KTE66, Escherichia coli KTE235, Escherichia coli KTE228, Escherichia coli KTE213, Escherichia coli KTE208, Escherichia coli KTE204, Escherichia coli KTE181, Escherichia coli KTE26, Escherichia coli KTE2, Escherichia coli 576-1, Escherichia coli STEC_C165-02, Escherichia coli TA280, Escherichia coli MS 198-1, Escherichia coli FVEC1302, Escherichia coli FVEC1412 Bacteria UP000007097, UP000036210, UP000027092, UP000017405, UP000017598, UP000017279, UP000017398, UP000017374, UP000017474, UP000016332, UP000016414, UP000016430, UP000016413, UP000016416, UP000016417, UP000016095, UP000016278, UP000016134, UP000016404, UP000016068, UP000016337, UP000016048, UP000016403, UP000016142, UP000016062, UP000016003, UP000016425, UP000016333, UP000016065, UP000016310, UP000016318, UP000016272, UP000016392, UP000016046, UP000016421, UP000016377, UP000016301, UP000016335, UP000016369, UP000016400, UP000015990, UP000016262, UP000014109, UP000014141, UP000014205, UP000014085, UP000014203, UP000014143, UP000014169, UP000014168, UP000014190, UP000010701, UP000010555, UP000010674, UP000010660, UP000010573, UP000010510, UP000010561, UP000010650, UP000010560, UP000010663, UP000010606, UP000010710, UP000010599, UP000010516, UP000010502, UP000010581, UP000010579, UP000010497, UP000010644, UP000010567, UP000010647, UP000010648, UP000004146, UP000006199, UP000004877, UP000003034, UP000002777, UP000004180 447199641, 218707613, 660681291, 635889032, 597594318, 553678964, 553670815, 553637960, 553636235, 553611540, 553368855, 535963641, 535454754, 535437103, 535435459, 535375180, 535339111, 535313709, 535302827, 535225677, 535188386, 535169229, 535139048, 535127789, 535097280, 535073623, 535050984, 535033948, 535025829, 535023373, 535010530, 534981327, 534968225, 534933988, 534912107, 534905305, 534848618, 534838911, 534777709, 534767824, 534722799, 534645138, 534617593, 534578459, 508546285, 508519265, 508502858, 508493997, 508490897, 508475213, 508385207, 508347447, 508273223, 431714866, 431697081, 431672499, 431577797, 431564582, 431526011, 431434239, 431422928, 431394155, 431323187, 431206047, 431176589, 431166566, 431135975, 431066156, 431047113, 431016433, 431001262, 430984855, 430949828, 430922149, 430871689, 388419885, 345330566, 331067358, 300358667, 298276238, 291425379, 226695850, 218434710 KEP20590.1, KDG69639.1, EYB40709.1, ESD95751.1, ESD88029.1, ESD56914.1, ESD55246.1, ESD31699.1, ESA95292.1, ERA63640.1, EQV94924.1, EQV77579.1, EQV75970.1, EQV17181.1, EQU81691.1, EQU56540.1, EQU45732.1, EQT69346.1, EQT32716.1, EQT13868.1, EQS84040.1, EQS73159.1, EQS43581.1, EQS20220.1, EQR97901.1, EQR81088.1, EQR73012.1, EQR70595.1, EQR58110.1, EQR29669.1, EQR16742.1, EQQ83054.1, EQQ61600.1, EQQ54919.1, EQP99359.1, EQP89886.1, EQP30251.1, EQP20524.1, EQO76168.1, EQO01536.1, EQN74431.1, EQN37126.1, EOX14575.1, EOW87938.1, EOW71883.1, EOW63138.1, EOW60078.1, EOW44631.1, EOV56248.1, EOV19044.1, EOU46383.1, ELJ79041.1, ELJ62227.1, ELJ38741.1, ELI50421.1, ELI37753.1, ELI02781.1, ELH15890.1, ELH05059.1, ELG77693.1, ELG10740.1, ELF04479.1, ELE76536.1, ELE66878.1, ELE37848.1, ELD74900.1, ELD57122.1, ELD29978.1, ELD16846.1, ELD01473.1, ELC69250.1, ELC42910.1, ELB95323.1, EIL79591.1, EGW63035.1, EGI38764.1, EFJ74537.1, EFI17759.1, EFE98419.1 WP_001276897.1, YP_002415132.1 B7NFT5 THIC_ECOLU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5887751 fig|1182714.3.peg.274, fig|1182731.3.peg.148, fig|1169324.3.peg.5181, fig|1169402.3.peg.4303, fig|1169363.3.peg.4559, fig|1182675.3.peg.4658, fig|1279005.3.peg.3346, fig|1181727.3.peg.4145, fig|1182673.3.peg.4796, fig|585056.7.peg.4688, fig|1181750.3.peg.4383, fig|1169345.3.peg.4757, fig|1169383.3.peg.4341, fig|1181736.3.peg.4829, fig|656379.3.peg.5237, fig|752787.3.peg.134, fig|1182687.3.peg.4476, fig|1182720.3.peg.21, fig|1181774.3.peg.3272, fig|1182708.3.peg.310, fig|1169315.3.peg.5195, fig|754085.3.peg.4811, fig|1308984.3.peg.4424, fig|1181779.3.peg.4115, fig|1181746.3.peg.4494, fig|1169380.3.peg.4496, fig|1182689.3.peg.4593, fig|1182717.3.peg.473, fig|656380.3.peg.5129, fig|1181754.3.peg.4692, fig|1169369.3.peg.4385, fig|656444.3.peg.5380, fig|1182737.3.peg.5099, fig|1169373.3.peg.4249, fig|1181759.3.peg.3857, fig|1169323.3.peg.4391, fig|749549.3.peg.1701, fig|1181771.3.peg.765, fig|1182661.3.peg.841 626 631 yes 438189 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 526994, 526993 Bacillus cereus AH1273, Bacillus cereus AH1272 Bacteria UP000001914, UP000001750 446737234, 228740859, 228734623 EEL91103.1, EEL85276.1 WP_000814490.1 fig|526993.3.peg.3098, fig|526994.3.peg.3374 586 586 yes 438190 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 475088, 521011 Methanosphaerula palustris, Methanosphaerula palustris E1-9c Archaea UP000002457 501693623, 219546830, 254784165 ACL17280.1 WP_012618599.1 B8GKY4 THIC_METPE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5771687 fig|521011.3.peg.2087 419 424 yes 438191 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 1396, 1428, 180868, 29339, 29338, 570416, 1261129, 1238885, 1232203, 1053196, 1053215, 1053208, 1279365, 1053200, 1053184, 527023 Bacillus cereus, Bacillus thuringiensis, Bacillus thuringiensis serovar mexicanensis, Bacillus thuringiensis serovar kurstaki, Bacillus thuringiensis serovar galleriae, Bacillus thuringiensis serovar kurstaki str. YBT-1520, Bacillus thuringiensis serovar kurstaki str. HD-1, Bacillus thuringiensis serovar aizawai str. Hu4-2, Bacillus thuringiensis serovar aizawai str. Leapi01, Bacillus cereus BMG1.7, Bacillus cereus ISP2954, Bacillus cereus HuB13-1, Bacillus thuringiensis serovar kurstaki str. HD73, Bacillus cereus HD73, Bacillus cereus BAG3X2-2, Bacillus thuringiensis serovar kurstaki str. T03a001 Bacteria UP000036076, UP000031834, UP000033450, UP000031926, UP000030909, UP000029029, UP000027772, UP000018758, UP000018703, UP000013997, UP000013989, UP000013991, UP000011818, UP000004172, UP000006965, UP000001372 446737225, 859591837, 827034916, 821628685, 803760962, 756040379, 734585280, 676318181, 661912345, 657514077, 633273364, 595880032, 565333541, 565327453, 500526118, 500439327, 500399840, 449026042, 402445967, 401108941, 228804262 KMQ13549.1, AKJ59654.1, KLA09752.1, KKB31299.1, AJK39481.1, AJA22492.1, AIM29020.1, AIE36530.1, KEH46952.1, AHZ54141.1, EXY09425.1, ETE96469.1, ETE90381.1, EOP91480.1, EOP52644.1, EOP15725.1, AGE81205.1, EJV77832.1, EJQ16870.1, EEM50876.1 WP_000814481.1 fig|1053215.3.peg.6401, fig|1053184.3.peg.5098, fig|527023.3.peg.1528, fig|1053196.3.peg.3764, fig|1279365.3.peg.5631, fig|1053208.3.peg.6350, fig|1053200.3.peg.4530 586 586 yes 438192 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 585057, 1281275, 1281114, 1281000, 1072459 Escherichia coli, Escherichia coli IAI39, Escherichia coli UMEA 3899-1, Escherichia coli HVH 187 (4-4471660), Escherichia coli HVH 53 (4-0631051), Escherichia coli O7:K1 str. CE10 Bacteria UP000036210, UP000000749, UP000016117, UP000016374, UP000016338, UP000002657 447199684, 218702629, 535917333, 535210523, 534739405, 349740643, 226695848, 218372615 ERA47982.1, EQT54497.1, EQO92522.1, AEQ15349.1 WP_001276940.1, YP_002410258.1 B7NRS7 THIC_ECO7I Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5892959 fig|1072459.4.peg.4709, fig|585057.4.peg.4520 626 631 yes 438193 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 43770, 525268 Corynebacterium striatum, Corynebacterium striatum ATCC 6940 Bacteria UP000034868, UP000005820 491672745, 227198636 EEI78684.1 WP_005528887.1 fig|525268.3.peg.607 577 585 yes 438194 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 244787, 598659 Nautilia profundicola, Nautilia profundicola AmH Bacteria UP000000448 506382069, 223589000, 254784168 ACM92736.1 WP_015901788.1 B9L811 THIC_NAUPA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} fig|598659.3.peg.328 461 461 yes 438195 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2296, 177437 Desulfobacterium autotrophicum, Desulfobacterium autotrophicum HRM2 Bacteria UP000000442 501880615, 223690507, 259517480 ACN13790.1 WP_012663038.1 C0QJ00 THIC_DESAH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5907992 fig|177437.4.peg.707 436 439 yes 438196 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 246787, 997874, 537012, 1263038 Bacteroides cellulosilyticus, Bacteroides cellulosilyticus CL02T12C19, Bacteroides cellulosilyticus DSM 14838, Bacteroides cellulosilyticus CAG:158 Bacteria, Environmental samples UP000061809, UP000003741, UP000003711, UP000018191 494398142, 392630603, 224522128, 524425625 EIY24591.1, EEF91233.1 WP_007210495.1 fig|537012.5.peg.929, fig|997874.3.peg.4844 573 573 yes 438197 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1428, 527029 Bacillus thuringiensis, Bacillus thuringiensis serovar pondicheriensis BGSC 4BA1 Bacteria UP000031834, UP000006660 446737211, 753330996, 228829512 AJG78505.1, EEM75140.1 WP_000814467.1 fig|527029.3.peg.5999 586 586 yes 438198 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 161889, 525263 Corynebacterium lipophiloflavum, Corynebacterium lipophiloflavum DSM 44291 Bacteria UP000006196 493895258, 227078553 EEI16516.1 WP_006841184.1 578 579 yes 438199 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 526985 Bacillus cereus Rock3-42 Bacteria UP000000325 228689092 EEL42916.1 593 596 yes 438200 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1491, 1248417, 536232 Clostridium botulinum, Clostridium botulinum Af84, Clostridium botulinum A2 str. Kyoto Bacteria UP000030128, UP000015061, UP000001374 502058007, 526282121, 226842441, 254784157 EPS55334.1, ACO85107.1 WP_012704583.1 C1FVP6 THIC_CLOBJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7553063 fig|536232.3.peg.3143 437 437 yes 438201 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526987 Bacillus cereus, Bacillus cereus Rock4-2 Bacteria UP000036076, UP000001443 446737220, 228700870 EEL53393.1 WP_000814476.1 fig|526987.3.peg.4378 586 586 yes 438202 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 527022 Bacillus thuringiensis serovar monterrey BGSC 4AJ1 Bacteria UP000000326 228810700 EEM57048.1 593 612 yes 438203 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 1053242, 526991, 526982, 526969, 405532 Bacillus cereus, Bacillus cereus VD184, Bacillus cereus AH676, Bacillus cereus Rock1-15, Bacillus cereus m1550, Bacillus cereus B4264 Bacteria UP000036076, UP000014028, UP000002292, UP000001923, UP000001371, UP000007096 446737229, 859531920, 500539033, 228722438, 228670767, 228629986, 218159970, 226695517 KMP55247.1, EOQ03819.1, EEL73832.1, EEL26075.1, EEK86637.1, ACK59962.1 WP_000814485.1 B7HEM8 THIC_BACC4 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 4670192, 7198657 fig|526991.3.peg.2881, fig|526982.3.peg.515, fig|526969.3.peg.4976, fig|1053242.3.peg.5940, fig|405532.4.peg.4951 586 586 yes 438204 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 320771 bacterium Ellin514 Bacteria UP000003688 223893714 EEF60172.1 fig|320771.5.peg.3482 642 643 yes 438205 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1290, 629742 Staphylococcus hominis, Staphylococcus hominis SK119 Bacteria UP000054429, UP000010117 488379893, 228270294 EEK11729.1 WP_002449278.1 fig|629742.3.peg.1479 580 580 yes 438206 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 203, 553218 Campylobacter rectus, Campylobacter rectus RM3267 Bacteria UP000003082 489034134, 222879447 EEF14539.1 WP_002944498.1 fig|553218.4.peg.1040 443 444 yes 438207 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 469595 Citrobacter sp. 30_2 Bacteria UP000004176 496062608, 226910427 EEH96345.1 WP_008787115.1 fig|469595.3.peg.4691 626 632 yes 438208 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 65393 Cyanothece sp. PCC 7424 Bacteria UP000002384 501599732, 218171607, 226695845 ACK70340.1 WP_012599283.1 B7KDN8 THIC_CYAP7 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5463835 fig|65393.13.peg.1954 458 459 yes 438209 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 770, 320483 Anaplasma marginale, Anaplasma marginale str. Florida Bacteria UP000007307 501859074, 222419170 ACM49193.1 WP_012658904.1 fig|1000937.3.peg.646, fig|517437.3.peg.380, fig|234826.10.peg.1015, fig|320483.3.peg.382 560 600 yes 438210 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 38284, 525260 Corynebacterium accolens, Corynebacterium accolens ATCC 49725 Bacteria UP000003641 491422550, 227077863 EEI15826.1 WP_005280347.1 fig|525260.4.peg.2204 620 643 yes 438211 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 309806, 204536 Sulfurihydrogenibium azorense, Sulfurihydrogenibium azorense Az-Fu1 Bacteria UP000001369 501936433, 225644451 ACN99501.1 WP_012674814.1 fig|204536.4.peg.1222 448 452 yes 438212 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 526997 Bacillus mycoides DSM 2048 Bacteria UP000001754 228746993 EEL96877.1 594 603 yes 438213 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 537013 Clostridium methylpentosum DSM 5476 Bacteria UP000003340 224947444 EEG28653.1 454 474 yes 438214 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 69966, 458233 Macrococcus caseolyticus, Macrococcus caseolyticus JCSC5402 Bacteria UP000001383 501847740, 222119670 WP_012656206.1 fig|458233.11.peg.381 571 571 yes 438215 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 258, 525372 Sphingobacterium spiritivorum, Sphingobacterium spiritivorum ATCC 33300 Bacteria UP000006241 489097453, 227242908 EEI92923.1 WP_003007330.1 fig|525372.3.peg.1677 605 605 yes 438216 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 562, 685038, 1409953, 1444198, 1444173, 1444144, 1444172, 1444250, 1445863, 1281263, 1281152, 1281277, 1281276, 1281228, 1281211, 1281209, 1281124, 1281101, 1281076, 1281071, 1281047, 1281016, 1280972, 1280963, 1280959, 1181741, 1206108, 1169374, 1169372, 1181737, 1181735, 591946 Escherichia coli, Escherichia coli O83:H1 str. NRG 857C, Escherichia coli MRSN 10204, Escherichia coli 6-319-05_S3_C3, Escherichia coli 6-319-05_S3_C2, Escherichia coli 6-175-07_S3_C1, Escherichia coli 6-175-07_S3_C2, Escherichia coli 3-105-05_S4_C2, Escherichia coli BIDMC 83, Escherichia coli UMEA 3693-1, Escherichia coli HVH 228 (4-7787030), Escherichia coli UMEA 4075-1, Escherichia coli UMEA 3955-1, Escherichia coli UMEA 3244-1, Escherichia coli UMEA 3193-1, Escherichia coli UMEA 3185-1, Escherichia coli HVH 197 (4-4466217), Escherichia coli HVH 171 (4-3191958), Escherichia coli HVH 143 (4-5674999), Escherichia coli HVH 138 (4-6066704), Escherichia coli HVH 111 (4-7039018), Escherichia coli HVH 78 (4-2735946), Escherichia coli HVH 21 (4-4517873), Escherichia coli HVH 9 (4-6942539), Escherichia coli HVH 4 (4-7276109), Escherichia coli KTE195, Escherichia coli J96, Escherichia coli KTE106, Escherichia coli KTE104, Escherichia coli KTE191, Escherichia coli KTE189, Escherichia coli LF82 Bacteria UP000036210, UP000008614, UP000034398, UP000027940, UP000027872, UP000027677, UP000027781, UP000027635, UP000024148, UP000017339, UP000015999, UP000016058, UP000016325, UP000016246, UP000015985, UP000016407, UP000016355, UP000016320, UP000016285, UP000016255, UP000016268, UP000016418, UP000016436, UP000015982, UP000016437, UP000014095, UP000006079, UP000010569, UP000010620, UP000010668, UP000010527, UP000010085 447199623, 387619307, 816071996, 660164251, 660132167, 660094591, 658732882, 650017653, 612262113, 554718739, 535987877, 535899023, 535898884, 535716634, 535634756, 535625867, 535264647, 535150583, 535062970, 535043520, 534922115, 534813223, 534614683, 534568339, 534554239, 508331256, 432345605, 431529513, 431525482, 430970368, 430960207, 312948568, 222035705 KKJ19690.1, KEM57245.1, KEM26355.1, KEL89631.1, KEJ73808.1, KDT41578.1, EZQ55737.1, ESK24066.1, ERA87579.1, ERA30137.1, ERA30004.1, EQY51348.1, EQX71227.1, EQX62498.1, EQU07983.1, EQS95406.1, EQS09724.1, EQR90560.1, EQQ71436.1, EQP64853.1, EQN71587.1, EQN27505.1, EQN13828.1, EOV03147.1, ELL40106.1, ELI06213.1, ELI02273.1, ELC87440.1, ELC78363.1, ADR29395.1 WP_001276879.1, YP_006122329.1 fig|685038.3.peg.4067, fig|1181735.3.peg.4605, fig|1169374.3.peg.4183, fig|1169372.3.peg.4265, fig|1206108.3.peg.418, fig|591946.4.peg.4080, fig|1181741.3.peg.4829, fig|1181737.3.peg.4930 626 631 yes 438217 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 373, 311402 Agrobacterium vitis, Agrobacterium vitis S4 Bacteria UP000056791, UP000001596 501840940, 221738055, 254784150 ACM38951.1 WP_012654193.1 B9K253 THIC_AGRVS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5481148 fig|311402.9.peg.1899 602 610 yes 438218 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526989 Bacillus cereus, Bacillus cereus F65185 Bacteria UP000036076, UP000000629 446737222, 228710663 EEL62636.1 WP_000814478.1 fig|526989.3.peg.1085 586 586 yes 438219 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 226900, 86661, 1227359, 1053241, 1053225, 526978, 1442 Bacillus cereus ATCC 14579, Bacillus weihenstephanensis FSL R5-860, Bacillus cereus VD169, Bacillus cereus VD045, Bacillus cereus BDRD-Cer4, Bacillus thuringiensis serovar tolworthi Bacteria UP000001417 UP000001417, UP000019049, UP000006956, UP000006596, UP000001373, UP000055316 30023259, 446737226, 573579050, 401280385, 401225431, 228652812, 29898819, 823271302, 47606144 ETT77407.1, EJR86306.1, EJR31980.1, EEL08694.1, AAP12091.1 NP_834890.1, WP_000814482.1 Q815D5 THIC_BACCR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 362428 fig|1053241.3.peg.4935, fig|526978.3.peg.5124, fig|226900.1.peg.5002, fig|1053225.3.peg.4538 586 586 yes 438220 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 467661 Rhodobacteraceae bacterium KLH11 Bacteria UP000005135 496031115, 221533453 EEE36441.1 WP_008755622.1 fig|467661.3.peg.2300 594 599 yes 438221 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 197221, 146786 Thermosynechococcus elongatus BP-1, Thermosynechococcus elongatus Bacteria UP000000440 22297877, 499368611, 29337046, 22294055 NP_681124.1, WP_011056189.1 Q8DLZ2 THIC_THEEB Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 197055 fig|197221.1.peg.333 459 461 yes 438222 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 43988, 395962, 41431 Cyanothece sp. PCC 8802, Cyanothece sp. PCC 8801 Bacteria UP000000415, UP000008204 501592397, 256591381, 218167927, 226695846 ACV02268.1, ACK66664.1 WP_012595931.1 B7K508 THIC_CYAP8 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7142493, 5423933 fig|395962.3.peg.1817, fig|41431.3.peg.2816 460 460 yes 438223 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 1235825, 1053238, 527027 Bacillus thuringiensis Sbt003, Bacillus cereus VD154, Bacillus thuringiensis serovar pakistani str. T13001 Bacteria UP000032407, UP000006967, UP000001911 446737231, 758672573, 401263191, 228798235 KIU76096.1, EJR69324.1, EEM45236.1 WP_000814487.1 fig|527027.3.peg.2546, fig|1053238.3.peg.4899 586 586 yes 438224 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 2335, 126738, 1288483, 309803 Thermotoga sp. RQ7, Thermotoga neapolitana LA10, Thermotoga neapolitana DSM 4359 Bacteria UP000031770, UP000029153, UP000000445 506400485, 752579479, 682466675, 221573154, 254784170 AJG39992.1, KFZ20947.1, ACM23966.1 WP_015920204.1 B9KAI3 THIC_THENN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5476113 fig|309803.4.peg.1785 424 424 yes 438225 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 39488, 411469, 1263078 Eubacterium hallii, Eubacterium hallii DSM 3353, Eubacterium hallii CAG:12 Bacteria, Environmental samples UP000003174, UP000018069 491492305, 224954286, 524365267 EEG35495.1 WP_005350036.1 fig|411469.3.peg.2354 434 434 yes 438226 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1386, 1396, 1324966, 1286404, 527021, 1053240, 541229, 527031, 527025 Bacillus cereus, Bacillus thuringiensis T01-328, Bacillus thuringiensis serovar thuringiensis str. IS5056, Bacillus thuringiensis Bt407, Bacillus cereus VD166, Bacillus thuringiensis CT43, Bacillus thuringiensis serovar berliner ATCC 10792, Bacillus thuringiensis serovar thuringiensis str. T01001 Bacteria UP000036076, UP000013487, UP000011719, UP000001233, UP000006618, UP000008135, UP000001925, UP000001376 446737194, 859528707, 859496404, 542048736, 452107110, 409176762, 401271442, 326943013, 228817405, 228784425, 228778041 KMP52092.1, KMP20811.1, ERI00473.1, AGG04050.1, AFV21067.1, EJR77459.1, AEA18909.1, EEM63491.1, EEM32447.1, EEM26313.1 WP_000814450.1 fig|541229.3.peg.5416, fig|1053240.3.peg.4400, fig|1209372.3.peg.706, fig|527031.3.peg.436, fig|1286404.3.peg.5376, fig|527021.3.peg.872, fig|527025.3.peg.504 586 586 yes 438227 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 224308, 1423, 1136873, 135461, 1221328, 1232554, 1437006, 1415167, 1147161, 1267547, 1220533, 1089443, 1409, 1204342, 1204343 Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis, Bacillus subtilis KCTC 1028, Bacillus subtilis subsp. subtilis, Bacillus subtilis subsp. subtilis str. AG1839, Bacillus subtilis subsp. subtilis str. JH642 substr. AG174, Bacillus subtilis QH-1, Bacillus subtilis PY79, Bacillus subtilis subsp. subtilis 6051-HGW, Bacillus subtilis MB73/2, Bacillus subtilis QB928, Bacillus subtilis subsp. subtilis str. SC-8, Bacillus sp., Bacillus subtilis BEST7003, Bacillus subtilis BEST7613 Bacteria UP000001570 UP000030629, UP000030083, UP000033059, UP000031530, UP000027111, UP000027293, UP000019465, UP000018540, UP000011759, UP000011743, UP000005251, UP000004759, UP000032808, UP000012981, UP000011218 255767202, 489326173, 857328881, 846135514, 807073216, 760456034, 749184838, 728888086, 728883774, 672775078, 672774182, 649014573, 649010209, 588499923, 558567437, 459388645, 452116818, 402480288, 351470178, 724426524, 723797329, 407963830, 407956560, 239938835, 225184829 KMN96716.1, AKN12961.1, AKC46422.1, KIX82109.1, AJE93548.1, AIY96480.1, AIY92169.1, KFH34653.1, KFH33758.1, AIC43495.1, AIC39263.1, EXF52335.1, AHA76843.1, AGG60231.1, EME07213.1, AFQ56797.1, EHA30354.1 NP_388759.2, WP_003233473.1 P45740 THIC_BACSU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6132113, 37411, 6127580, 6136503 fig|1147161.3.peg.947, fig|1267547.3.peg.1579, fig|535025.4.peg.2013, fig|1148.72.peg.920, fig|1089443.3.peg.3498, fig|1220533.3.peg.923, fig|535024.3.peg.4151, fig|1192196.3.peg.3316, fig|224308.113.peg.909, fig|535026.3.peg.946 590 590 yes 438228 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 37919, 632772 Rhodococcus opacus, Rhodococcus opacus B4 Bacteria UP000028488, UP000002212 502002466, 226239796 WP_012689100.1 fig|632772.3.peg.1912 541 548 yes 438229 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 904, 1203555, 568816, 563191, 1263033 Acidaminococcus sp. HPA0509, Acidaminococcus intestinalis RYC-MR95, Acidaminococcus sp. D21, Acidaminococcus intestini CAG:325 Bacteria, Environmental samples UP000014391, UP000007093, UP000004571, UP000018020 496305945, 512072676, 350278119, 226904376, 524447606 EPD71955.1, AEQ21309.1, EEH90294.1 WP_009015123.1 fig|1203555.3.peg.1344, fig|563191.3.peg.665, fig|568816.4.peg.52 434 434 yes 438230 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 546264 Neisseria flavescens NRL30031/H210 Bacteria UP000004457 224951612 EEG32821.1 fig|546264.5.peg.1788 473 473 yes 438231 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526988 Bacillus cereus, Bacillus cereus Rock4-18 Bacteria UP000036076, UP000001384 446737205, 228706626 EEL58837.1 WP_000814461.1 fig|526988.3.peg.5644 586 586 yes 438232 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 518637 Eubacterium biforme DSM 3989 Bacteria UP000004315 218217534 EEC91072.1 fig|518637.5.peg.465 446 446 yes 438233 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 33036, 525255 Anaerococcus tetradius, Anaerococcus tetradius ATCC 35098 Bacteria UP000003744 490973992, 227218552 EEI83792.1 WP_004835783.1 fig|525255.3.peg.224 430 431 yes 438234 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28108, 314275, 1774373 Alteromonas macleodii, Alteromonas macleodii 'Deep ecotype', Alteromonas mediterranea DE Bacteria UP000031168, UP000059372, UP000001870 501508730, 327549575, 226695514 AEA96293.1 WP_012516667.1 B4S2W4 THIC_ALTMD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6894465 fig|314275.3.peg.2311 636 642 yes 438235 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 405531 Bacillus cereus, Bacillus cereus G9842 Bacteria UP000036076, UP000006744 446737219, 218541678, 226695516 ACK94072.1 WP_000814475.1 B7IPY9 THIC_BACC2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2433026, 7192819 fig|405531.7.peg.5222 586 586 yes 438236 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 526983 Bacillus cereus, Bacillus cereus Rock3-28 Bacteria UP000036076, UP000001379 446737199, 228677552 EEL31802.1 WP_000814455.1 fig|526983.3.peg.4381 586 586 yes 438237 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1405, 526999, 526998 Bacillus mycoides, Bacillus mycoides Rock3-17, Bacillus mycoides Rock1-4 Bacteria UP000035933, UP000006661, UP000001053 489297585, 228759909, 228751896 EEM08883.1, EEM01658.1 WP_003205081.1 fig|526999.3.peg.130, fig|526998.3.peg.5564 586 586 yes 438238 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1033854, 396588 Thioalkalivibrio sulfidophilus, Thioalkalivibrio sp. HL-EbGR7 Bacteria UP000002383 501777426, 219994982 ACL71584.1 WP_012637072.1 fig|396588.3.peg.480 626 629 yes 438239 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 1053228, 1053222, 526973 Bacillus cereus, Bacillus cereus VD102, Bacillus cereus MSX-D12, Bacillus cereus m1293 Bacteria UP000036076, UP000006985, UP000006971, UP000002290 446737214, 859540961, 859520218, 859494853, 401238445, 401215525, 228584056 KMP64041.1, KMP43987.1, KMP19287.1, EJR44886.1, EJR22241.1, EEK42209.1 WP_000814470.1 fig|1163722.3.peg.4360, fig|1053222.3.peg.358, fig|526973.3.peg.1093, fig|1053228.3.peg.5130 586 586 yes 438240 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 1396, 1415784, 1053177, 1053168, 1053237, 1053212, 1053188, 526981 Bacillus cereus, Bacillus toyonensis BCT-7112, Bacillus cereus BAG2O-2, Bacillus cereus BAG1O-2, Bacillus cereus VD148, Bacillus cereus HuB5-5, Bacillus cereus BAG5O-1, Bacillus cereus Rock1-3 Bacteria UP000036076, UP000017860, UP000014538, UP000006595, UP000006982, UP000006616, UP000007001, UP000000324 446737200, 859539631, 557474585, 513454799, 401640072, 401263034, 401175598, 401127630, 228664687 KMP62771.1, AHA08407.1, EPF03562.1, EJS57805.1, EJR69168.1, EJQ82799.1, EJQ35344.1, EEL20178.1 WP_000814456.1 fig|1053212.3.peg.4997, fig|1053237.3.peg.338, fig|526981.3.peg.5632, fig|1053177.3.peg.5079, fig|1053188.3.peg.4457, fig|1053168.3.peg.336 586 586 yes 438241 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 391601 Stenotrophomonas sp. SKA14 Bacteria UP000003991 495543410, 219722096 EED40621.1 WP_008267989.1 fig|391601.3.peg.529 613 614 yes 438242 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 271, 498848 Thermus aquaticus, Thermus aquaticus Y51MC23 Bacteria UP000037685, UP000058660 489139012, 218242774 EED09309.1 WP_003048789.1 fig|498848.5.peg.2098 433 435 yes 438243 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 427926, 555088 Dethiobacter alkaliphilus, Dethiobacter alkaliphilus AHT 1 Bacteria UP000006443 495794577, 225167229 EEG76050.1 WP_008519156.1 fig|555088.4.peg.3033 422 432 yes 438244 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 427926, 555088 Dethiobacter alkaliphilus, Dethiobacter alkaliphilus AHT 1 Bacteria UP000006443 495794578, 225167230 EEG76051.1 WP_008519157.1 fig|555088.4.peg.3034 420 426 yes 438245 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 410072, 470146, 1263070 Coprococcus comes, Coprococcus comes ATCC 27758, Coprococcus comes CAG:19 Bacteria, Environmental samples UP000003793, UP000017957 495649523, 225205935, 524437760 EEG88289.1 WP_008374102.1 fig|470146.3.peg.2522 435 436 yes 438246 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1521, 394503 Clostridium cellulolyticum, Clostridium cellulolyticum H10 Bacteria UP000001349 506405724, 219999738 ACL76339.1 WP_015925443.1 fig|394503.6.peg.2043 436 436 yes 438247 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 100886, 451640 Catenibacterium mitsuokai, Catenibacterium mitsuokai DSM 15897 Bacteria UP000004579 493551093, 224525701 EEF94806.1 WP_006504752.1 fig|451640.5.peg.436 434 435 yes 438248 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 85085, 452863 Arthrobacter chlorophenolicus, Arthrobacter chlorophenolicus A6 Bacteria UP000002505 506417689, 219859850 ACL40192.1 WP_015937408.1 fig|452863.6.peg.2910 589 605 yes 438249 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 721785, 535289 Acidovorax ebreus, Acidovorax ebreus TPSY Bacteria UP000000450 506394537, 221731584, 254784161 ACM34404.1 WP_015914256.1 B9MFQ3 THIC_ACIET Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5788878 fig|535289.3.peg.3018 609 614 yes 438250 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 33075, 240015 Acidobacterium capsulatum, Acidobacterium capsulatum ATCC 51196 Bacteria UP000002207 506378105, 225792447 ACO32537.1 WP_015897824.1 fig|240015.3.peg.2647 481 484 yes 438251 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1219, 93058 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9202 Bacteria UP000002804 488896341, 221538201 EEE40654.1 WP_002807447.1 fig|93058.3.peg.749 453 456 yes 438252 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 114616, 460265 Methylobacterium nodulans, Methylobacterium nodulans ORS 2060 Bacteria UP000008207 506411317, 219949006 ACL59398.1 WP_015931036.1 fig|460265.11.peg.5145 619 627 yes 438253 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 234621 Rhodococcus erythropolis PR4 Bacteria UP000002204 226184092 fig|234621.6.peg.1968 532 543 yes 438254 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 1405, 86662, 1053236, 1053246, 1053247, 1053248, 1053227, 526972 Bacillus mycoides, Bacillus weihenstephanensis, Bacillus cereus VD146, Bacillus cereus VDM019, Bacillus cereus VDM022, Bacillus cereus VDM034, Bacillus cereus VD078, Bacillus cereus AH621 Bacteria UP000035933, UP000030313, UP000014020, UP000013999, UP000006598, UP000007003, UP000006976, UP000001909 487942712, 859598462, 753371574, 666939320, 500418405, 500314314, 401303628, 401295029, 401239053, 228613540 KMQ20005.1, AJH18860.1, KEZ81049.1, EOP33770.1, EOO34963.1, EJS09189.1, EJS00654.1, EJR45485.1, EEK70670.1 WP_002016178.1 fig|1053246.3.peg.5167, fig|1053199.3.peg.343, fig|526997.3.peg.5472, fig|1053227.3.peg.327, fig|1053198.3.peg.5104, fig|1053197.3.peg.5103, fig|1053247.3.peg.368, fig|1053236.3.peg.5791, fig|1053248.3.peg.4533, fig|526972.3.peg.198 586 586 yes 438255 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 86661, 1053223, 527030 Bacillus cereus VD014, Bacillus thuringiensis serovar huazhongensis BGSC 4BD1 Bacteria UP000006607, UP000000627 446737236, 401209433, 228835750 EJR16192.1, EEM81114.1 WP_000814492.1 fig|1053223.3.peg.4963, fig|527030.3.peg.437 586 586 yes 438256 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 392484, 637616 Methylophaga thiooxidans, Methylophaga thiooxidans DMS010 Bacteria UP000029999, UP000004679 495567488, 224462252 EEF78529.1 WP_008292067.1 fig|637616.3.peg.2842 601 603 yes 438257 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 354, 1283331, 1283330, 322710 Azotobacter vinelandii, Azotobacter vinelandii CA6, Azotobacter vinelandii CA, Azotobacter vinelandii DJ Bacteria UP000012988, UP000012989, UP000002424 502036904, 482535725, 482529969, 226721407 AGK18851.1, AGK13096.1, ACO80578.1 WP_012702945.1 fig|1283330.3.peg.4265, fig|1283331.3.peg.4267, fig|322710.5.peg.4207 627 628 yes 438258 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 549169, 279714 Lutiella nitroferrum, Lutiella nitroferrum 2002 Bacteria UP000003165 496242030, 224601013 EEG07196.1 WP_008955415.1 fig|279714.3.peg.3418 635 636 yes 438259 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1428, 527019 Bacillus thuringiensis, Bacillus thuringiensis IBL 200 Bacteria UP000031834, UP000001220 446737239, 228848566 EEM93413.1 WP_000814495.1 fig|527019.3.peg.6487 586 586 yes 438260 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 485, 242231, 528351, 528358, 528356, 528354, 528352, 528346, 528345 Neisseria gonorrhoeae, Neisseria gonorrhoeae FA 1090, Neisseria gonorrhoeae F62, Neisseria gonorrhoeae PID332, Neisseria gonorrhoeae PID18, Neisseria gonorrhoeae MS11, Neisseria gonorrhoeae FA19, Neisseria gonorrhoeae 35/02, Neisseria gonorrhoeae 1291 Bacteria UP000027314, UP000000535, UP000004656, UP000004686, UP000005770, UP000016457, UP000005783, UP000004706, UP000004698 489783082, 59802349, 636864094, 592987899, 291611870, 268621420, 268584488, 268584250, 268551659, 268549074, 228225069, 226511807, 59719244, 800200817, 75432329 KDN01050.1, AHL49759.1, EFF40939.1, EEZ53820.1, EEZ49164.1, EEZ48926.1, EEZ46678.1, EEZ44492.1, ACP82734.1, EEH61152.1, AAW90649.1 WP_003686973.1, YP_209061.1 Q5F588 THIC_NEIG1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 820185, 5769173 fig|528352.5.peg.2348 624 633 yes 438261 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 212663, 575788 Vibrio tasmaniensis, Vibrio splendidus LGP32 Bacteria UP000009100 501628891, 254784172, 218324003 WP_012605077.1 B7VMV7 THIC_VIBTL Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2681804, 5240039 fig|575788.4.peg.4025 640 649 yes 438262 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1396, 1053245, 1053202, 1053209, 1053187, 526984 Bacillus cereus, Bacillus cereus VD214, Bacillus cereus HuA2-3, Bacillus cereus HuB2-9, Bacillus cereus BAG4X2-1, Bacillus cereus Rock3-29 Bacteria UP000036076, UP000014027, UP000014033, UP000005024, UP000004148, UP000006652 446737203, 500421249, 500419590, 402465076, 402420990, 228683724 EOP36379.1, EOP34930.1, EJV96763.1, EJV53259.1, EEL37675.1 WP_000814459.1 fig|1053202.3.peg.300, fig|1053209.3.peg.341, fig|526984.3.peg.5593, fig|1053187.3.peg.413, fig|1053245.3.peg.5500 586 586 yes 438263 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 169292, 548476 Corynebacterium aurimucosum, Corynebacterium aurimucosum ATCC 700975 Bacteria UP000002077 497876251, 227454413 ACP33166.1 WP_010190407.1 fig|548476.3.peg.1611 595 600 yes 438264 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 31899, 521460 Caldicellulosiruptor bescii, Caldicelulosiruptor becscii DSM 6725 Bacteria UP000007723 506387255, 222455247 ACM59509.1 WP_015906974.1 fig|521460.8.peg.394 419 420 yes 438265 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 471881 Proteus penneri ATCC 35198 Bacteria UP000006464 225201882 EEG84236.1 fig|471881.3.peg.1699 477 490 yes 438266 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 28901, 476213 Salmonella enterica, Salmonella enterica subsp. enterica serovar Paratyphi C strain RKS4594 Bacteria UP000054489, UP000001599 446030555, 224470232, 254784169 ACN48062.1 WP_000108410.1 C0Q2S6 THIC_SALPC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5680801 fig|476213.4.peg.4057 626 631 yes 438267 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 1428, 527024 Bacillus thuringiensis, Bacillus thuringiensis serovar tochigiensis BGSC 4Y1 Bacteria UP000031834, UP000001913 446737213, 228771305 EEM19780.1 WP_000814469.1 fig|527024.3.peg.991 586 586 yes 438268 phosphomethylpyrimidine synthase 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) ISS 201, 306263 Campylobacter lari, Campylobacter lari RM2100 Bacteria UP000035197, UP000007727 501872835, 222539247 ACM64348.1 WP_012661731.1 fig|306263.1.peg.204 433 433 yes 1888202 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 69222 Erwinia mallotivora Bacteria UP000019918 736937459, 594398807 EXU76713.1 WP_034934473.1 631 644 yes 1888203 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 176102, 1307437 Pseudoalteromonas agarivorans, Pseudoalteromonas agarivorans S816 Bacteria UP000012320 490726556, 478441314 ENN97418.1 WP_004589049.1 fig|1307437.4.peg.3486 645 650 yes 1888204 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29449, 1328306 Rhizobium etli, Rhizobium etli bv. mimosae str. Mim1 Bacteria UP000015261 528843087, 528180718 AGS24042.1 WP_020922700.1 601 610 yes 1888205 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1341165, 1107311 Flavobacterium enshiense, Flavobacterium sp. DK69 Bacteria UP000018305 559196704, 558895825, 700549085 ESU23140.1, KGO95999.1 WP_023573299.1 607 607 yes 1888206 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67780, 634503 Edwardsiella ictaluri, Edwardsiella ictaluri 93-146 Bacteria UP000054228, UP000001485 506349917, 861555568, 238867713 KMQ78692.1, ACR67424.1 WP_015869636.1 fig|1027360.4.peg.761, fig|634503.3.peg.160 627 643 yes 1888207 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28133, 997352 Prevotella nigrescens, Prevotella nigrescens ATCC 33563 Bacteria UP000004575 490500756, 339609452 EGQ14325.1 WP_004366874.1 526 526 yes 1888208 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487173, 742743 Dialister succinatiphilus, Dialister succinatiphilus YIT 11850 Bacteria UP000003277 496135610, 371934718 EHO62498.1 WP_008860117.1 fig|742743.3.peg.1658 434 435 yes 1888209 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263094 Parabacteroides merdae CAG:48 Environmental samples UP000018407 524591788 567 568 yes 1888210 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1207058 Hyphomonas sp. L-53-1-40 Bacteria UP000024938 736815170, 630780715 KCZ62086.1 WP_034816879.1 625 626 yes 1888211 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 909768, 1310773 Acinetobacter baumannii 883425 Bacteria UP000021851 691164345, 593633256 EXS13784.1 WP_032070639.1 621 625 yes 1888212 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1151118 Arthrobacter sp. 161MFSha2.1 Bacteria 517606004 WP_018776212.1 597 619 yes 1888213 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 488, 546266 Neisseria mucosa, Neisseria mucosa ATCC 25996 Bacteria UP000029875, UP000003344 489840350, 288566031 EFC87591.1 WP_003744055.1 625 633 yes 1888214 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 97253, 1235802 Eubacterium plexicaudatum, Eubacterium plexicaudatum ASF492 Bacteria UP000012589 490167211, 476615759 EMZ22776.1 WP_004065857.1 fig|1235802.3.peg.4036 434 434 yes 1888215 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913083 Salmonella enterica subsp. enterica serovar Uganda str. R8-3404 Bacteria UP000003915 353640295 EHC85335.1 fig|913083.3.peg.4664 314 318 no 1888216 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 669359 Geminocystis herdmanii Bacteria 515863771 WP_017294399.1 458 460 yes 1888217 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454005 Candidatus Accumulibacter sp. BA-94 Bacteria UP000020878 589617006 EXI88239.1 637 638 yes 1888218 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 373994 Rivularia sp. PCC 7116 Bacteria UP000010380 504932771, 427372351 AFY56307.1 WP_015119873.1 fig|373994.3.peg.4121 459 460 yes 1888219 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1276920 Arthrobacter gangotriensis Lz1y Bacteria UP000012015 470217445 EMQ98261.1 fig|1276920.7.peg.2282 593 600 yes 1888220 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1226324, 1262968 Blautia sp. KLE 1732, Ruminococcus sp. CAG:90 Bacteria, Environmental samples UP000016485, UP000018096 548206247, 524726857 WP_022426187.1 434 434 yes 1888221 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 1038921, 1144323 Pseudomonas chlororaphis subsp. aureofaciens 30-84, Pseudomonas sp. GM17 Bacteria UP000007291, UP000007273 495196643, 397884006, 398127918 EJL00492.1, EJM17319.1 WP_007921432.1 fig|1144323.3.peg.433, fig|1038921.4.peg.4357 628 629 yes 1888222 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1004836 Gluconacetobacter sp. SXCC-1 Bacteria UP000005513 494639056, 329761930 EGG78420.1 WP_007397000.1 605 613 yes 1888223 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1422, 1295642 Geobacillus stearothermophilus, Geobacillus stearothermophilus NUB3621 Bacteria UP000036745, UP000023566 763019331, 612120448 EZP78450.1 WP_043903491.1 573 573 yes 1888224 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 118797 Lipotes vexillifer Mammals 602717245 XP_007468816.1 341 341 yes 1888225 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 940614, 682795 Granulicella mallensis, Acidobacterium sp. MP5ACTX8 Bacteria UP000007113 504031109, 358752834 AEU36224.1 WP_014265103.1 487 493 yes 1888226 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158172 Thioalkalivibrio sp. ALE16 Bacteria 518412744 WP_019582951.1 627 629 yes 1888227 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 359110, 1117958 Pseudomonas extremaustralis, Pseudomonas extremaustralis 14-3 substr. 14-3b Bacteria UP000019800 498249142, 610833282 EZI29782.1 WP_010563298.1 627 629 yes 1888228 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446578 Escherichia coli, Escherichia coli O121:H7 str. 2009C-3299 Bacteria UP000036210, UP000024067 693044084, 822943932, 607730790 KLG68736.1, EZE13213.1 WP_032214926.1 626 631 yes 1888229 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1285583 Corynebacterium casei LMG S-19264 Bacteria UP000019226 582015992 AHI19338.1 522 536 yes 1888230 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 907261 Ralstonia syzygii R24 Bacteria 344173255 629 631 yes 1888231 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1049786, 1049780 Leptospira borgpetersenii str. Brem 307, Leptospira borgpetersenii str. Brem 328 Bacteria UP000012110, UP000012166 464193730, 464197937 EMN13083.1, EMN15822.1 208 208 no 1888232 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281168 Escherichia coli, Escherichia coli KOEGE 71 (186a) Bacteria UP000036210, UP000016372 545255289, 535448369 EQV88639.1 WP_021551604.1 626 631 yes 1888233 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1126, 1134457 Microcystis aeruginosa, Microcystis aeruginosa TAIHU98 Bacteria UP000010932 488824005, 440174615 ELP53984.1 WP_002736411.1 fig|1134457.3.peg.2107 457 460 yes 1888234 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 310300, 1321819, 1235813 Bacteroides pyogenes, Bacteroides pyogenes F0041, Bacteroides pyogenes JCM 10003 Bacteria UP000016496, UP000018823 545406342, 542988973, 567222922 ERI84852.1 WP_021645655.1 563 563 yes 1888235 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1407055 Thaumarchaeota archaeon N4 Archaea 851355821, 563490099 WP_048194049.1 V6AQQ1 V6AQQ1_9ARCH 446 446 yes 1888236 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310643 Acinetobacter baumannii, Acinetobacter baumannii 299505 Bacteria UP000028632, UP000019839 691067930, 587893695 EXB82233.1 WP_032010062.1 621 625 yes 1888237 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1248917 Porphyrobacter sp. AAP82 Bacteria 516261018 WP_017664981.1 615 623 yes 1888238 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 394751, 1117313 Pseudoalteromonas arctica, Pseudoalteromonas arctica A 37-1-2 Bacteria UP000016505 498241114, 540221986 ERG08719.1 WP_010555270.1 645 650 yes 1888239 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116052 Escherichia coli, Escherichia coli P0299917.6 Bacteria UP000036210, UP000012273 485887482, 476979580 ENC66651.1 WP_001480909.1 fig|1116052.3.peg.4398 626 631 yes 1888240 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 526986 Bacillus cereus Rock3-44 Bacteria UP000006654 228695621 EEL48481.1 fig|526986.3.peg.3107 70 70 no 1888241 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 587753, 294, 1144322, 1144326 Pseudomonas chlororaphis, Pseudomonas fluorescens, Pseudomonas sp. GM16, Pseudomonas sp. GM24 Bacteria UP000027603, UP000060991, UP000007511, UP000007503 495190946, 722457455, 749427705, 398110267, 398151942 KHA74004.1, KII38631.1, EJM00174.1, EJM40474.1 WP_007915736.1 fig|1144322.3.peg.3702, fig|1144326.3.peg.2001 628 629 yes 1888242 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35830 Acetivibrio cellulolyticus Bacteria 497938215 WP_010252371.1 432 432 yes 1888243 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263009 Firmicutes bacterium CAG:212 Environmental samples UP000018345 524250002 435 436 yes 1888244 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 648885 Methylobacterium sp. MB200 Bacteria 516054514 WP_017485097.1 623 630 yes 1888245 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1121098 Bacteroides massiliensis B84634 = DSM 17679 Bacteria UP000017831 482607727 EOA55798.1 fig|1121098.3.peg.1457 567 567 yes 1888246 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 478801 Kytococcus sedentarius DSM 20547 Bacteria UP000006666 256689168 ACV06970.1 fig|478801.4.peg.2387 547 554 yes 1888247 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 544, 1006003, 1288347, 1454056, 1114920 Citrobacter freundii ATCC 8090, Citrobacter freundii GTC 09479, Citrobacter freundii RLS1, Citrobacter freundii NBRC 12681 Bacteria UP000032868, UP000011742, UP000022937, UP000032872 489938713, 411770748, 668704861, 455644053, 588302962, 689841767 EKS54497.1, KFB90842.1, EMF23167.1, EXF32237.1 WP_003842020.1 fig|1288347.3.peg.2210, fig|1006003.3.peg.4532 626 632 yes 1888248 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217713 Acinetobacter sp. NIPH 809 Bacteria UP000013034 490794184, 479870680 ENU22237.1 WP_004656330.1 fig|1217713.3.peg.3045 626 631 yes 1888249 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 883118 Klebsiella oxytoca, Klebsiella oxytoca 10-5243 Bacteria UP000030350, UP000003069 490211302, 376375167 EHS87963.1 WP_004109700.1 fig|883118.3.peg.5446 626 631 yes 1888250 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 72361 Bacillus vallismortis Bacteria 498013572 WP_010327728.1 590 590 yes 1888251 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1333651, 1435051 Bifidobacterium moukalabense, Bifidobacterium moukalabense DSM 27321 Bacteria UP000019155 736876266, 575769776 ETY71234.1 WP_034875901.1 651 880 yes 1888252 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53399, 670307 Hyphomicrobium denitrificans, Hyphomicrobium denitrificans 1NES1 Bacteria UP000005952 505411688, 484582738 AGK58771.1 WP_015598790.1 681 689 yes 1888253 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1172186 Mycobacterium sp. 360MFTsu5.1 Bacteria 518944737 WP_020100612.1 536 540 yes 1888254 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 160808, 743299 Acidithiobacillus ferrivorans, Acidithiobacillus ferrivorans SS3 Bacteria UP000029069, UP000009220 503795195, 343775378 AEM47934.1 WP_014029189.1 626 627 yes 1888255 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44249, 996640 Paenibacillus sp. ICGEB2008 Bacteria UP000032906 515997852, 808108323 KKD52574.1 WP_017428435.1 591 614 yes 1888256 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 1347340 Campylobacter jejuni, Campylobacter jejuni 4031 Bacteria UP000065538, UP000016893 549779444, 549035948 WP_022552232.1 430 430 yes 1888257 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1267533 Acidobacteriaceae bacterium KBS 83 Bacteria 522202004 WP_020709471.1 488 490 yes 1888258 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 769, 574556 Anaplasma centrale, Anaplasma centrale str. Israel Bacteria UP000000630 502644459, 269848744 ACZ49388.1 WP_012880839.1 fig|574556.4.peg.823 557 600 yes 1888259 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 483, 546262 Neisseria cinerea, Neisseria cinerea ATCC 14685 Bacteria UP000003294 489773380, 269145011 EEZ71429.1 WP_003677281.1 625 633 yes 1888260 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 397260, 1123269 Sphingomonas sanxanigenens, Sphingomonas sanxanigenens DSM 19645 = NX02 Bacteria UP000018851 644243720, 569544641 AHE56258.1 WP_025294381.1 609 613 yes 1888261 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33995 Gluconacetobacter europaeus Bacteria UP000037566 517920413 WP_019090621.1 605 613 yes 1888262 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 121723 Photobacterium sp. SKA34 Bacteria UP000005284 493693564, 89049707 EAR55257.1 WP_006643454.1 636 639 yes 1888263 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053206 Bacillus cereus, Bacillus cereus HuA4-10 Bacteria UP000036076, UP000006977 488073430, 401180040 EJQ87203.1 WP_002144827.1 fig|1053206.3.peg.331 586 586 yes 1888264 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1128911, 493475 Glaciecola arctica, Glaciecola sp. BSs20135 Bacteria UP000006327 494891288, 410150103 WP_007617334.1 fig|493475.3.peg.993 651 661 yes 1888265 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1217700 Acinetobacter sp. CIP 70.18 Bacteria UP000013084 491342629, 480342034 ENX62206.1 WP_005200568.1 fig|1221303.3.peg.578, fig|1217700.3.peg.372 626 631 yes 1888266 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1686, 566552 Bifidobacterium catenulatum, Bifidobacterium catenulatum DSM 16992 Bacteria UP000029016 489931623, 212661295 EEB21870.1 WP_003834941.1 fig|566552.4.peg.722 603 871 yes 1888267 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 742735, 999403, 999405, 999409, 999410, 742736 Clostridium clostridioforme 2_1_49FAA, Clostridium clostridioforme 90A1, Clostridium clostridioforme 90A4, Clostridium clostridioforme 90B1, Clostridium clostridioforme CM201, Clostridium clostridioforme WAL-7855 Bacteria UP000003999, UP000013287, UP000013027, UP000013273, UP000013098, UP000037306 355382802, 480687044, 480769401, 480660779, 480646627, 891189771 EHG29896.1, ENZ30053.1, ENZ68078.1, ENZ04708.1, ENY90981.1, KMW20821.1 fig|999408.3.peg.5101, fig|999403.4.peg.371, fig|999410.3.peg.2692, fig|742735.4.peg.3579, fig|999405.4.peg.2628, fig|999409.3.peg.3618, fig|999406.3.peg.3786 468 484 yes 1888268 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 671, 1219065 Vibrio proteolyticus, Vibrio proteolyticus NBRC 13287 Bacteria UP000016570 545470834, 543440182 WP_021707310.1 640 647 yes 1888269 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 88036 Selaginella moellendorffii Plants UP000001514 302793991, 300153569 EFJ20207.1 XP_002978760.1 549 561 yes 1888270 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 992160 Yersinia pestis PY-59 Bacteria UP000003918 391596151 EIS40115.1 178 201 no 1888271 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 396317, 1227452 Haloarcula amylolytica, Haloarcula amylolytica JCM 13557 Archaea 495584224, 445771566 EMA22622.1 WP_008308803.1 M0KML6 M0KML6_9EURY 456 480 yes 1888272 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 104264, 1328323, 979, 867900 Cellulophaga geojensis KL-A, Cellulophaga lytica, Cellulophaga lytica DSM 7489 Bacteria UP000019275, UP000029048, UP000007487 503386778, 584430600, 682033572, 324322229 EWH15261.1, AIM60696.1, ADY29694.1 WP_013621439.1 fig|867900.3.peg.1865 619 619 yes 1888273 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 779, 254945 Ehrlichia ruminantium, Ehrlichia ruminantium str. Welgevonden Bacteria UP000006739 499468339, 81557328, 57161105, 58417593 WP_011154979.1 Q5HBN2 THIC_EHRRW Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1759176 fig|254945.25.peg.321 555 555 yes 1888274 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2711 Citrus sinensis Plants UP000027120 568870599 XP_006488487.1 546 1224 yes 1888275 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626929, 762984 Bacteroides clarus, Bacteroides clarus YIT 12056 Bacteria UP000010321 496412117, 328527039 EGF54050.1 WP_009120981.1 560 561 yes 1888276 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 302484, 1227460 Haloferax larsenii, Haloferax larsenii JCM 13917 Archaea 494807312, 445726501 ELZ78117.1 WP_007542720.1 M0H2Y8 M0H2Y8_9EURY 440 465 yes 1888277 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28072 Nostoc sp. PCC 7524 Bacteria UP000010378 504954229, 427368206 AFY50927.1 WP_015141331.1 456 457 yes 1888278 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1465, 1399144 Brevibacillus laterosporus, Brevibacillus laterosporus PE36 Bacteria UP000016844 550163558, 548618406 ERM16780.1 WP_022586244.1 591 592 yes 1888279 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 863643, 635013 Thermincola potens, Thermincola potens JR Bacteria UP000002377 502884474, 296030659 ADG81427.1 WP_013119450.1 fig|635013.3.peg.591 424 426 yes 1888280 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 863643, 635013 Thermincola potens, Thermincola potens JR Bacteria UP000002377 502884475, 296030660 ADG81428.1 WP_013119451.1 fig|635013.3.peg.592 422 432 yes 1888281 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 412963, 882378 Burkholderia rhizoxinica, Burkholderia rhizoxinica HKI 454 Bacteria UP000007437 503193991, 312169779 WP_013428652.1 fig|882378.3.peg.345 641 643 yes 1888282 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 135577, 1321370, 283942 Idiomarina loihiensis, Idiomarina loihiensis GSL 199, Idiomarina loihiensis L2TR Bacteria UP000013960, UP000001171 499553234, 507119254, 56178884, 81599907 AGM35634.1, AAV81606.1 WP_011234017.1 Q5QUD0 THIC_IDILO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 862688 fig|1321370.3.peg.775, fig|283942.3.peg.1005 565 568 yes 1888283 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 86661, 1053170, 1053173, 1053174, 1053175, 1053176, 1428 Bacillus cereus BAG1X1-1, Bacillus cereus BAG1X2-1, Bacillus cereus BAG1X2-2, Bacillus cereus BAG1X2-3, Bacillus cereus BAG2O-1, Bacillus thuringiensis Bacteria UP000014000, UP000014036, UP000014016, UP000013990, UP000014022, UP000031834 506988910, 500309956, 500326026, 500336789, 500338001, 500386473, 896578949 EOO31421.1, EOO45316.1, EOO55627.1, EOO56798.1, EOP02584.1, AKR12049.1 WP_016079709.1 fig|1053175.3.peg.5798, fig|1053173.3.peg.5116, fig|1053170.3.peg.347, fig|1053174.3.peg.281, fig|1053176.3.peg.5102 586 586 yes 1888284 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1335411 Mycobacterium abscessus MAB_082312_2258 Bacteria UP000018509 560376644 ESV57065.1 408 420 no 1888285 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1335411 Mycobacterium abscessus MAB_082312_2258 Bacteria UP000018509 560376645 ESV57066.1 126 126 no 1888286 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34073 Variovorax paradoxus Bacteria UP000050323 518488295 WP_019658502.1 623 627 yes 1888287 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 821, 702446, 1339350, 1339351, 1263056 Bacteroides vulgatus, Bacteroides vulgatus PC510, Bacteroides vulgatus str. 3775 SL(B) 10 (iv), Bacteroides vulgatus str. 3775 SR(B) 19, Bacteroides vulgatus CAG:6 Bacteria, Environmental samples UP000061587, UP000004563, UP000028134, UP000028110, UP000018171 492444367, 294447829, 649523894, 649527742, 524824043 EFG16404.1, KDS31518.1, KDS35257.1 WP_005845959.1 566 566 yes 1888288 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406, 349520 Paenibacillus polymyxa, Paenibacillus polymyxa E681 Bacteria UP000031922, UP000002227 503073815, 305856777 ADM68565.1 WP_013308748.1 fig|349520.5.peg.681 594 602 yes 1888289 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 556264 Fusobacterium sp. D11 Bacteria UP000004650 289717793 EFD81805.1 433 433 yes 1888290 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1260, 525282 Finegoldia magna, Finegoldia magna ATCC 53516 Bacteria UP000004063 488923846, 297575097 EFH93816.1 WP_002834921.1 433 433 yes 1888291 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 683305 Frankia sp. BMG5.23 Bacteria UP000027007 759904506, 631848124 KDA43283.1 WP_043590829.1 612 647 yes 1888292 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 156456, 861450 Anaeroglobus geminatus, Anaeroglobus geminatus F0357 Bacteria UP000005481 493843062, 364562770 EHM40602.1 WP_006790156.1 fig|861450.3.peg.1098 434 434 yes 1888293 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 651 681 no 1888294 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 515620 Eubacterium eligens ATCC 27750 Bacteria UP000001476 238872009 ACR71719.1 fig|515620.4.peg.656 441 448 yes 1888295 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262920 Prevotella sp. CAG:1124 Environmental samples UP000017956 524086060 566 567 yes 1888296 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 672, 216895, 196600 Vibrio vulnificus, Vibrio vulnificus CMCP6, Vibrio vulnificus YJ016 Bacteria UP000054370, UP000002275, UP000002675 499391543, 675337481, 27360522, 29337042, 47606103, 37200143 AIL71995.1, AAO09458.1 WP_011079010.1 Q8DDL4, Q7MGM3 THIC_VIBVU, THIC_VIBVY Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 309168, 676235 fig|196600.1.peg.3273, fig|216895.1.peg.905 639 647 yes 1888297 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1279, 1388318 Staphylococcus aureus M0480 Bacteria UP000021174 515742170, 579931405 EUZ68084.1 WP_017174770.1 580 580 yes 1888298 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169157 Streptomyces sp. CNQ766 Bacteria 517668540 WP_018838748.1 598 602 yes 1888299 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76728 Streptomyces vitaminophilus Bacteria UP000050867 517195297 WP_018384115.1 593 594 yes 1888300 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2020, 471852 Thermomonospora curvata, Thermomonospora curvata DSM 43183 Bacteria UP000001918 502615872, 268311629 ACY98003.1 WP_012852787.1 fig|471852.6.peg.2494 574 578 yes 1888301 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116016 Escherichia coli, Escherichia coli 2785200 Bacteria UP000036210, UP000012261 487584118, 476211318 EMW31474.1 WP_001724174.1 fig|1116016.3.peg.4640 626 631 yes 1888302 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2421, 484019 Thermosipho africanus, Thermosipho africanus TCF52B Bacteria UP000002453 501576041, 217037708 ACJ76230.1 WP_012580424.1 fig|484019.3.peg.1819 420 425 yes 1888303 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 93220, 1416914 Pandoraea pnomenusa, Pandoraea pnomenusa 3kgm Bacteria UP000035080, UP000018768 560177799, 601109902, 698965435, 559152206 AHN76804.1, AIU26590.1, AHB04780.1 WP_023594641.1 637 638 yes 1888304 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 998520 Pseudoalteromonas sp. NW 4327 Bacteria UP000018825 567929091, 566571826 ETJ49538.1 WP_024031495.1 645 650 yes 1888305 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 127891, 1236970 Bacillus wakoensis, Bacillus wakoensis JCM 9140 Bacteria UP000018890 736737765, 568810084 WP_034741674.1 594 595 yes 1888306 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28080, 888826 Campylobacter upsaliensis, Campylobacter upsaliensis JV21 Bacteria UP000005813 490402503, 315481410 EFU72037.1 WP_004277189.1 432 432 yes 1888307 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 103731, 1179773 Saccharothrix espanaensis, Saccharothrix espanaensis DSM 44229 Bacteria UP000006281 504910804, 407880149 WP_015097906.1 fig|1179773.3.peg.472 547 549 yes 1888308 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392998 Candidatus Methanoperedens nitroreducens Archaea 851155249, 630831813 KCZ73522.1 WP_048089022.1 A0A062V8A6 A0A062V8A6_9EURY 421 421 yes 1888309 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217718 Cupriavidus sp. BIS7 Bacteria 518280901 WP_019451109.1 623 625 yes 1888310 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1164990, 1165095 Richelia intracellularis, Richelia intracellularis HM01 Bacteria UP000019767, UP000054004 495504788, 471317711 WP_008229435.1 fig|1165095.3.peg.1140 457 459 yes 1888311 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 101020 Fragaria vesca subsp. vesca Plants 764558630, 764558626 XP_011460924.1, XP_011460923.1 541 651 yes 1888312 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 240125, 525368 Mycobacterium parascrofulaceum, Mycobacterium parascrofulaceum ATCC BAA-614 Bacteria UP000003653 494293470, 295896954 EFG76579.1 WP_007167550.1 542 548 yes 1888313 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1331244 Bordetella bronchiseptica SBL-F6116 Bacteria UP000027106 633982890 KDE01040.1 574 577 no 1888314 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 944547 Arcobacter sp. L Bacteria UP000001290 504285822, 345470633 WP_014472924.1 fig|944547.4.peg.210 448 450 yes 1888315 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 212717 Clostridium tetani E88 Bacteria UP000001412 28202982, 47606162 AAO35426.1 Q897B2 THIC_CLOTE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 327562 fig|212717.1.peg.711 456 457 yes 1888316 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1412525 Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121541 Bacteria UP000069229 603590379 AHS53299.1 479 481 yes 1888317 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29466, 1316254 Veillonella parvula, Veillonella parvula HSIVP1 Bacteria UP000054707, UP000015940 544717826, 530807366 EQC67323.1 WP_021147832.1 434 434 yes 1888318 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168480, 1208314 Gordonia namibiensis, Gordonia namibiensis NBRC 108229 Bacteria UP000035058 493921703, 403402917 WP_006866695.1 fig|1208314.3.peg.2073 549 558 yes 1888319 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47951 Vibrio cyclitrophicus Bacteria 515166649 WP_016795171.1 640 649 yes 1888320 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1335308 Burkholderia vietnamiensis AU4i Bacteria UP000016616 544732338, 543287554 ERJ35345.1 WP_021162062.1 642 643 yes 1888321 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47839 Mycobacterium triplex Bacteria UP000028880 738517954, 620037908 WP_036466432.1 542 545 yes 1888322 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 48736, 329, 428406, 658080, 658664 Ralstonia pickettii, Ralstonia pickettii 12D, Ralstonia sp. 5_2_56FAA, Ralstonia sp. 5_7_47FAA Bacteria UP000029114, UP000008208, UP000016506, UP000003629 496532751, 674758611, 240866921, 348615187, 308921005 KFL23976.1, ACS64582.1, EGY64718.1, EFP66651.1 WP_009239442.1 fig|658664.3.peg.1900, fig|658080.3.peg.2194, fig|428406.5.peg.3922 633 635 yes 1888323 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 179, 1048260, 1441628, 1660083 Leptospirillum ferriphilum ML-04, Leptospirillum ferriphilum YSK, Leptospirillum sp. Group II 'CF-1' Bacteria UP000006177, UP000027059, UP000037560 504773676, 406773843, 640838277, 902830462 AFS53268.1, AIA30325.1, AKS23770.1 WP_014960778.1 fig|1048260.3.peg.1130, fig|315749.4.peg.686 458 462 yes 1888324 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 360055 Zavarzinella formosa Bacteria 521958665 WP_020470270.1 443 444 yes 1888325 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 301375, 1110509 Methanosaeta harundinacea, Methanosaeta harundinacea 6Ac Archaea UP000053961, UP000005877 504398497, 357208790 AET63410.1 WP_014585599.1 G7WJW9 G7WJW9_METH6 420 427 yes 1888326 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 484, 596320 Neisseria flavescens, Neisseria flavescens SK114 Bacteria UP000005533 489782633, 241318764 EER55290.1 WP_003686524.1 fig|596320.3.peg.1889 625 629 yes 1888327 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1298609 Psychrobacter sp. JCM 18901 Bacteria UP000019501 589896709 61 63 no 1888328 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1298609 Psychrobacter sp. JCM 18901 Bacteria UP000019501 589896708 59 64 no 1888329 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1298609 Psychrobacter sp. JCM 18901 Bacteria UP000019501 589896707 286 286 no 1888330 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 624, 766162, 766163, 216599, 754077 Shigella sonnei, Shigella sonnei 3226-85, Shigella sonnei 3233-85, Shigella sonnei 53G, Shigella sonnei str. Moseley Bacteria UP000054188, UP000004377, UP000004480, UP000003892, UP000007276 447199674, 391289959, 391280037, 323167464, 397894627, 904354793, 904092964, 904031282, 905256773, 904050152, 904589725, 904291648, 904036363, 904253439, 905321501, 904237657, 905311589, 905486695, 903595863, 903888669, 904114208, 904330771, 904266825, 903714933, 904140919, 904247737, 903798189, 904064964, 903825820, 903644546, 903893770, 903784506, 903586712, 904781107, 904389188, 903959683, 903766421, 903917177, 905410912, 904560398, 905087390, 905400935, 904850136, 903572414, 904296465, 904300835, 904953856, 906018617, 903563696, 904672740, 904203578 EIQ48441.1, EIQ38713.1, EFZ53172.1, EJL11068.1 WP_001276930.1 fig|754077.4.peg.5134, fig|216599.1.peg.3429, fig|766163.3.peg.4607, fig|766162.3.peg.574 626 631 yes 1888331 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 927669, 927668 Pseudanabaena biceps, Pseudanabaena biceps PCC 7429 Bacteria UP000011201 497311137, 443020494 ELS34445.1 WP_009625354.1 fig|927668.3.peg.434 455 461 yes 1888332 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54261, 589924 Ferroglobus placidus, Ferroglobus placidus DSM 10642 Archaea UP000002613 502731952, 288895066 ADC66603.1 WP_012966936.1 D3S2B2 D3S2B2_FERPA 428 428 yes 1888333 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 640511 Burkholderia sp. CCGE1002 Bacteria UP000002190 502854910, 295436854 ADG16024.1 WP_013089886.1 fig|640511.6.peg.2010 642 643 yes 1888334 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3659 Cucumis sativus Plants UP000029981 449465814, 700210698 KGN65794.1 XP_004150622.1 550 649 yes 1888335 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 546265 Neisseria lactamica ATCC 23970 Bacteria UP000029053 269209438 EEZ75893.1 265 430 no 1888336 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 546265 Neisseria lactamica ATCC 23970 Bacteria UP000029053 269209439 EEZ75894.1 360 360 yes 1888337 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1773, 1397940 Mycobacterium tuberculosis, Mycobacterium tuberculosis TKK_04_0031 Bacteria UP000065426, UP000025689 686023440, 625776345 KCF27162.1 WP_031719218.1 544 547 yes 1888338 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 199, 1242968 Campylobacter concisus, Campylobacter concisus UNSWCS Bacteria UP000066049, UP000016620 544653279, 543211280 ERJ30338.1 WP_021087165.1 431 431 yes 1888339 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1432561, 1432558 Klebsiella pneumoniae IS39, Klebsiella pneumoniae ISC21 Bacteria UP000019190, UP000019189 571164386, 571245309 468 470 yes 1888340 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173366 Methylocystis rosea Bacteria 517219537 WP_018408355.1 608 608 yes 1888341 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1207055 Sphingobium sp. C100 Bacteria UP000018867 567389284, 566046176 ETI65372.1 WP_024018279.1 633 644 yes 1888342 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 94254, 471854 Dyadobacter fermentans, Dyadobacter fermentans DSM 18053 Bacteria UP000002011 506292152, 254948977 ACT93677.1 WP_015811927.1 fig|471854.4.peg.5605 630 630 yes 1888343 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 936375 Mogibacterium sp. CM50 Bacteria UP000003142 497329636, 402272453 EJU21673.1 WP_009643849.1 fig|936375.3.peg.703 436 437 yes 1888344 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262767 Catenibacterium sp. CAG:290 Environmental samples UP000018308 524724356 434 435 yes 1888345 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 327275 Shewanella sp. HN-41 Bacteria UP000002956 494921879, 335865220 EGM70270.1 WP_007647915.1 655 684 yes 1888346 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 629263 Pseudomonas syringae pv. pisi str. 1704B Bacteria UP000004986 330942825 EGH45345.1 413 413 yes 1888347 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 629263 Pseudomonas syringae pv. pisi str. 1704B Bacteria UP000004986 330942826 EGH45346.1 214 215 no 1888348 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547163 Mycobacterium vulneris Bacteria UP000028872 738492616, 602523553 WP_036442201.1 533 536 yes 1888349 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1203578 Pseudomonas sp. HPB0071 Bacteria UP000017050 498496347, 476728388 ENA33167.1 WP_010797077.1 625 625 yes 1888350 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 613, 768492, 768490, 768493 Serratia sp. AS9, Serratia sp. AS12, Serratia sp. AS13 Bacteria UP000008883, UP000008884, UP000008882 503577060, 333471698, 333489198, 333959295 AEF43408.1, AEF48360.1, AEG26068.1 WP_013811136.1 fig|768492.3.peg.250, fig|768493.3.peg.248, fig|768490.3.peg.249 633 647 yes 1888351 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33034, 525919 Anaerococcus prevotii, Anaerococcus prevotii DSM 20548 Bacteria UP000002294 506258269, 256798486 ACV29141.1 WP_015778044.1 fig|525919.4.peg.1055 430 431 yes 1888352 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262934 Prevotella sp. CAG:732 Environmental samples UP000018039 524600254 563 564 yes 1888353 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35797, 314278 Nitrococcus mobilis, Nitrococcus mobilis Nb-231 Bacteria UP000003374 491145239, 88789292 EAR20423.1 WP_005003639.1 fig|314278.3.peg.2452 626 628 yes 1888354 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33034, 879305 Anaerococcus prevotii, Anaerococcus prevotii ACS-065-V-Col13 Bacteria UP000005286 490972686, 325479476 EGC82572.1 WP_004834479.1 fig|879305.3.peg.310 430 431 yes 1888355 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 138563, 182217 Helicobacter cetorum, Helicobacter cetorum MIT 00-7128 Bacteria UP000005010 504474382, 384556282 AFI04616.1 WP_014661484.1 fig|182217.3.peg.1435 442 443 yes 1888356 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 561230 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. carotovorum PC1 Bacteria UP000053038, UP000002736 502365672, 251753200 ACT11276.1 WP_012772945.1 fig|561230.3.peg.219 631 651 yes 1888357 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173850, 90371 Salmonella enterica, Salmonella enterica subsp. enterica serovar Indiana str. ATCC 51959, Salmonella enterica subsp. enterica serovar Typhimurium Bacteria UP000054489, UP000017330, UP000028938 555242026, 554264315, 902842432 ESH00522.1, KNB26539.1 WP_023226532.1 626 631 yes 1888358 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33910, 749927, 1221524, 713604 Amycolatopsis mediterranei, Amycolatopsis mediterranei U32, Amycolatopsis mediterranei RB, Amycolatopsis mediterranei S699 Bacteria UP000028400, UP000000328, UP000015621, UP000010110 502995319, 300790377, 650435743, 532234122, 340532061, 398323025, 299799891 KDU93621.1, AGT89101.1, AEK47266.1, AFO81972.1, ADJ50266.1 WP_013230295.1, YP_003770668.1 fig|713604.4.peg.8804, fig|749927.5.peg.8899 534 536 yes 1888359 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 387090, 547042 Bacteroides coprophilus, Bacteroides coprophilus DSM 18228 Bacteria UP000014073 495417454, 224018064 EEF76063.1 WP_008142152.1 fig|547042.5.peg.1272 564 564 yes 1888360 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1510, 1121335 Clostridium stercorarium, Clostridium stercorarium subsp. stercorarium DSM 8532 Bacteria UP000012072 505172869, 442741603, 472400057 AGC69292.1, AGI40256.1 WP_015359971.1 432 432 yes 1888361 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1217694 Acinetobacter sp. CIP 64.2 Bacteria UP000013107 491382319, 480180451 ENX16863.1 WP_005240201.1 fig|1217694.3.peg.1261, fig|981223.3.peg.928 626 631 yes 1888362 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262887 Eubacterium sp. CAG:252 Environmental samples UP000017970 524420843 434 435 yes 1888363 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1202532 Flavobacterium sp. F52 Bacteria UP000002690 395434697 EJG00641.1 fig|1202532.3.peg.3045 615 615 yes 1888364 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 75612 Pseudomonas mandelii Bacteria 498150094 WP_010464250.1 627 629 yes 1888365 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 113287, 887929 Pseudoramibacter alactolyticus, Pseudoramibacter alactolyticus ATCC 23263 Bacteria UP000004754 493647479, 315621300 EFV01270.1 WP_006599073.1 421 430 no 1888366 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358, 1435057 Agrobacterium tumefaciens, Agrobacterium tumefaciens LBA4213 (Ach5) Bacteria UP000064781, UP000029229 740707658, 806954921, 586950628 AKC08230.1, AHK02417.1 WP_038492947.1 599 607 yes 1888367 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1125, 1160282, 1160279 Microcystis aeruginosa PCC 9806, Microcystis sp. T1-4 Bacteria UP000003273, UP000004501 488868835, 389788922, 389834643 WP_002781074.1 fig|1160279.3.peg.4433, fig|1160282.3.peg.3438 457 460 yes 1888368 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1125980 Vibrio harveyi CAIM 1792 Bacteria UP000011926 471344689 EMR37454.1 585 585 yes 1888369 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487316, 1217677 Acinetobacter soli, Acinetobacter soli NIPH 2899 Bacteria UP000053120, UP000018433 491082492, 480020399 ENV61364.1 WP_004944106.1 fig|1217677.3.peg.593 627 631 yes 1888370 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 244573, 768671 Thiocapsa marina, Thiocapsa marina 5811 Bacteria UP000005459 494357630, 343800260 EGV18207.1 WP_007193619.1 fig|768671.3.peg.2904 628 630 yes 1888371 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29430, 1217659, 1331660 Acinetobacter haemolyticus, Acinetobacter haemolyticus CIP 64.3, Acinetobacter haemolyticus MTCC 9819 Bacteria UP000017667, UP000018423 491225647, 480077685, 523906143 ENW16334.1, EPR88241.1 WP_005083934.1 fig|1217659.3.peg.2854, fig|1221297.3.peg.955 626 631 yes 1888372 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 1316586 Fusobacterium nucleatum, Fusobacterium nucleatum CTI-5 Bacteria UP000017135 552908039, 551100782 ERT32094.1 WP_023039451.1 433 433 yes 1888373 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 170652, 945543 Vibrio brasiliensis, Vibrio brasiliensis LMG 20546 Bacteria UP000004371 493935081, 323312572 EGA65706.1 WP_006879473.1 640 646 yes 1888374 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1499681, 1262851 Collinsella sp. MS5, Collinsella sp. CAG:289 Bacteria, Environmental samples UP000017952 548164231, 524673043 WP_022386446.1 443 445 yes 1888375 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 63128, 1114856 Natronorubrum tibetense, Natronorubrum tibetense GA33 Archaea 493012757, 445583140 ELY37474.1 WP_006092191.1 L9VK17 L9VK17_9EURY 459 477 yes 1888376 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 336 336 yes 1888377 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 192 Azospirillum brasilense Bacteria UP000065707 917051151, 646257388, 612172121 AIB11861.1, EZQ08740.1 WP_051657863.1 604 613 yes 1888378 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 868131 Methanobacterium sp. SWAN-1 Archaea UP000009231 503590642, 333824554 AEG17216.1 WP_013824718.1 F6D1I8 F6D1I8_METPW 423 423 yes 1888379 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 410332, 1223542 Gordonia malaquae, Gordonia malaquae NBRC 108250 Bacteria UP000035009 495657738, 453361904 WP_008382317.1 fig|1223542.3.peg.4246 545 562 yes 1888380 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317, 1204471, 1205751, 1260626 Pseudomonas syringae, Pseudomonas syringae BRIP34876, Pseudomonas syringae BRIP34881, Pseudomonas syringae pv. syringae B64 Bacteria UP000028642, UP000011214, UP000011211, UP000011219 489517537, 440365126, 440363194, 443281292 ELQ02240.1, ELQ00364.1, ELS40297.1 WP_003422352.1 fig|1260626.4.peg.8409, fig|1204471.4.peg.1648, fig|1176491.3.peg.2574, fig|1205751.4.peg.3438 627 629 yes 1888381 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 442 515 yes 1888382 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 392589 Perlucidibaca piscinae Bacteria 551335533 WP_022954963.1 641 643 yes 1888383 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55208, 1175631 Pectobacterium wasabiae, Pectobacterium wasabiae CFBP 3304 Bacteria UP000029436, UP000002756 492807501, 679617774, 684988319, 401704808 KFX00604.1, KGA26238.1, EJS95008.1 WP_005970310.1 fig|1175631.4.peg.1749 631 651 yes 1888384 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 877455 Methanobacterium sp. 17A1 Archaea UP000007490 325331676 ADZ10738.1 F0T7Q6 F0T7Q6_METLA 429 429 yes 1888385 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 944559 Paenibacillus sp. HGF7 Bacteria UP000003445 333608849 EGL20135.1 492 494 yes 1888386 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1157944 Arthrobacter sp. 131MFCol6.1 Bacteria 517603248 WP_018773456.1 607 616 yes 1888387 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 561, 1169321 Escherichia coli KTE114 Bacteria UP000014101 447199658, 508274116 EOU47263.1 WP_001276914.1 fig|1169321.3.peg.1047, fig|754330.3.peg.2890 626 631 yes 1888388 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 670905 Escherichia coli, Escherichia coli 1357 Bacteria UP000036210, UP000004409 447199659, 323182093 EFZ67503.1 WP_001276915.1 fig|670905.3.peg.4277 626 631 yes 1888389 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39491, 515619, 1263079, 657318, 657317 Eubacterium rectale, Eubacterium rectale ATCC 33656, Eubacterium rectale CAG:36, Eubacterium rectale DSM 17629, Eubacterium rectale M104/1 Bacteria, Environmental samples UP000049472, UP000001477, UP000018162, UP000007057, UP000008802 502255929, 238876551, 524538360, 291525993, 291527273 ACR76258.1 WP_012743351.1 fig|657318.4.peg.2456, fig|657317.3.peg.1460, fig|515619.6.peg.2196 435 436 yes 1888390 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 564, 550694 Escherichia fergusonii, Escherichia fergusonii B253 Bacteria UP000033773, UP000003166 447199650, 324110906 EGC04898.1 WP_001276906.1 fig|550694.3.peg.4608 626 631 yes 1888391 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 550685 Escherichia coli, Escherichia coli E101 Bacteria UP000036210, UP000005338 447199651, 371607566 EHN96136.1 WP_001276907.1 fig|550685.3.peg.4482 626 631 yes 1888392 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 869669, 656420, 754082 Escherichia coli, Escherichia coli 1.2741, Escherichia coli M863, Escherichia coli STEC_7v Bacteria UP000036210, UP000004300, UP000003884, UP000003796 447199657, 914354968, 386139218, 323963787, 327250465 KOA26966.1, EIG80373.1, EGB59286.1, EGE62175.1 WP_001276913.1 fig|656420.3.peg.5037, fig|754082.3.peg.4582, fig|869669.3.peg.1452 626 631 yes 1888393 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 550676, 1328432, 1169376, 1181739, 754089, 1281260 Escherichia coli, Escherichia coli B185, Escherichia coli BWH 32, Escherichia coli KTE112, Escherichia coli KTE193, Escherichia coli STEC_MHI813, Escherichia coli UMEA 3671-1 Bacteria UP000036210, UP000004669, UP000017274, UP000010537, UP000010651, UP000004617, UP000016084 447199654, 729937584, 291430823, 555087198, 431545168, 430976424, 345368886, 535828125 KHI28463.1, EFF03820.1, ESM30359.1, ELI19836.1, ELC93290.1, EGX00878.1, EQZ60536.1 WP_001276910.1 fig|1181739.3.peg.3337, fig|550676.3.peg.4252, fig|1169376.3.peg.4572, fig|754089.3.peg.4381 626 631 yes 1888394 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1386080, 1628753, 1423 Bacillus sp. EGD-AK10, Bacillus sp. LM 4-2, Bacillus subtilis Bacteria UP000016535, UP000033095, UP000030083 516294208, 542118601, 811155097, 751877841, 751886389, 751887568, 751894625 ERI46358.1, AKE22715.1, KIN29855.1, KIN38220.1, KIN39374.1, KIN46284.1 WP_017697515.1 590 590 yes 1888395 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 585343555, 921356093, 922090452 WP_024225178.1 626 631 yes 1888396 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392540 Acinetobacter nectaris CIP 110549 Bacteria UP000023785 554733227 ESK38390.1 594 597 yes 1888397 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1432553 Klebsiella pneumoniae IS46 Bacteria UP000019191 571233125 260 266 no 1888398 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1432553 Klebsiella pneumoniae IS46 Bacteria UP000019191 571233124 363 365 yes 1888399 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 693988 Bilophila sp. 4_1_30 Bacteria UP000003718 496773853, 345041724 EGW45856.1 WP_009368116.1 fig|693988.3.peg.1475 419 427 no 1888400 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36820, 1220583 Gordonia aichiensis, Gordonia aichiensis NBRC 108223 Bacteria UP000010988 491313850, 441447828 WP_005171828.1 fig|1220583.3.peg.1183 554 566 yes 1888401 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 304371 Methanocella paludicola SANAE Archaea UP000001882 282157513 D1Z1M9 D1Z1M9_METPS 417 424 yes 1888402 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1328385, 1328375, 72407 Klebsiella pneumoniae, Klebsiella pneumoniae BWH 30, Klebsiella pneumoniae MGH 43, Klebsiella pneumoniae subsp. pneumoniae Bacteria UP000036212, UP000017470, UP000022322, UP000060052 556448827, 839409394, 839603865, 555090731, 583695438, 815980970 KME86219.1, KMG78861.1, ESM33862.1, EWF57637.1, AKE78179.1 WP_023313809.1 626 631 yes 1888403 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 85874, 1089553 Thermacetogenium phaeum, Thermacetogenium phaeum DSM 12270 Bacteria UP000053326, UP000000467 504863759, 409105859 AFV11984.1 WP_015050861.1 431 433 yes 1888404 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 909768, 1310696, 1310695, 1310905, 1310914, 1310906, 1310907, 1310908, 1310910, 1310911, 1310912, 1310913, 1310669, 1310833, 1310761, 1183155, 575564, 1147131 Acinetobacter baumannii 1592897, Acinetobacter baumannii 259052, Acinetobacter baumannii 25977_1, Acinetobacter baumannii 25977_10, Acinetobacter baumannii 25977_2, Acinetobacter baumannii 25977_3, Acinetobacter baumannii 25977_4, Acinetobacter baumannii 25977_6, Acinetobacter baumannii 25977_7, Acinetobacter baumannii 25977_8, Acinetobacter baumannii 25977_9, Acinetobacter baumannii 6112, Acinetobacter baumannii 796380-1375, Acinetobacter baumannii 88816, Acinetobacter nosocomialis Ab22222, Acinetobacter sp. RUH2624, Acinetobacter nosocomialis 28F Bacteria UP000020575, UP000020089, UP000021005, UP000020894, UP000021014, UP000021814, UP000022608, UP000021349, UP000021253, UP000021988, UP000027276, UP000027220, UP000027035, UP000020037, UP000007353, UP000002771, UP000019193 493629202, 602189243, 588227611, 593906072, 593917376, 593902755, 593898922, 593893460, 593888253, 593886193, 593882770, 630640202, 630484757, 630570666, 593667411, 407440784, 260405836, 553285124 EYT18414.1, EXE99908.1, EXT61700.1, EXT72630.1, EXT58455.1, EXT54691.1, EXT49460.1, EXT44490.1, EXT42485.1, EXT39179.1, KCZ33955.1, KCX95412.1, KCY75435.1, EXS46705.1, EKF47301.1, EEW99324.1 WP_006581166.1 fig|575564.3.peg.2251, fig|1221296.3.peg.1866, fig|1183155.3.peg.2995 621 625 yes 1888405 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1157943 Mycobacterium sp. 155 Bacteria 517431408 WP_018602354.1 540 542 yes 1888406 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29497 Vibrio splendidus Bacteria UP000050463 515653067 WP_017085667.1 640 649 yes 1888407 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 517697885 WP_018868093.1 627 629 yes 1888408 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 653685, 492670, 1423138, 1423 Bacillus methylotrophicus, Bacillus amyloliquefaciens SQR9, Bacillus subtilis Bacteria UP000032090, UP000025235, UP000030083 740672093, 817596770, 631800194, 703584387 AKF77348.1, AHZ14859.1, AIW36747.1 WP_038457382.1 590 590 yes 1888409 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1716, 1203619, 1203625, 1203627, 1203632 Corynebacterium sp. KPL1986, Corynebacterium sp. KPL1996, Corynebacterium sp. KPL1998, Corynebacterium sp. KPL2004 Bacteria UP000017151, UP000017139, UP000017132, UP000017129 552765779, 550746532, 550743142, 550772331, 550772323 ERS46020.1, ERS42688.1, ERS70418.1, ERS70413.1 WP_023017903.1 621 643 yes 1888410 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053226 Bacillus cereus, Bacillus cereus VD048 Bacteria UP000036076, UP000006960 488095046, 401221486 EJR28100.1 WP_002166443.1 fig|1053226.3.peg.4543 586 586 yes 1888411 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 586 609 yes 1888412 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158182 Thioalkalivibrio sp. ALE31 Bacteria 517706597 WP_018876805.1 627 629 yes 1888413 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 539813 Enterobacter sp. R18-2 Bacteria 498111779 WP_010425935.1 626 631 yes 1888414 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 882104, 593750 Methanoregula formicicum, Methanoregula formicicum SMSP Archaea UP000010824 505098512, 432137724 AGB02651.1 WP_015285614.1 L0HFU6 L0HFU6_METFS 420 425 yes 1888415 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2374, 1009370 Acetonema longum, Acetonema longum DSM 6540 Bacteria UP000003240 490196205, 337275839 EGO64287.1 WP_004094750.1 432 433 yes 1888416 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 593105 Pantoea sp. SC-1 Bacteria UP000004320 496383663, 380739284 EIC00348.1 WP_009092653.1 fig|593105.3.peg.3530 631 640 yes 1888417 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 501479 Citreicella sp. SE45 Bacteria UP000005759 496159712, 260421004 EEX14255.1 WP_008884219.1 591 594 yes 1888418 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144339 Pseudomonas sp. GM80 Bacteria UP000007301 495354532, 398248630 EJN34035.1 WP_008079253.1 fig|1144339.3.peg.1201 628 629 yes 1888419 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2055, 1316928 Gordonia terrae, Gordonia terrae C-6 Bacteria UP000013569 498819436, 492205266 EON30336.1 WP_010844949.1 fig|1316928.3.peg.4678 552 562 yes 1888420 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204038, 198628 Dickeya dadantii, Dickeya dadantii 3937 Bacteria UP000006859 503081058, 306526525 ADM96455.1 WP_013315942.1 fig|198628.6.peg.247 631 655 yes 1888421 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 903918 Acinetobacter baumannii WC-323 Bacteria UP000009884 497194148, 425493085 EKU59332.1 WP_009508410.1 fig|903918.3.peg.444 626 631 yes 1888422 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33906 Actinopolyspora mortivallis Bacteria 518694032 WP_019855725.1 545 552 yes 1888423 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1908 Streptomyces globisporus Bacteria 497746292 WP_010060476.1 593 596 yes 1888424 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 195, 887317 Campylobacter coli, Campylobacter coli 2680 Bacteria UP000062643, UP000005956 488879729, 380521976 EIA47678.1 WP_002791954.1 fig|887317.3.peg.865 429 430 yes 1888425 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 141692 Nocardiopsis halophila Bacteria 516109335 WP_017539915.1 552 554 yes 1888426 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 657324 Butyrivibrio fibrisolvens 16/4 Bacteria UP000008796 291519821 434 435 yes 1888427 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 342113, 441162 Burkholderia oklahomensis, Burkholderia oklahomensis C6786 Bacteria UP000029424, UP000057998 497788470, 685679762, 772970477 AIO66882.1, AJX30535.1 WP_010102654.1 642 643 yes 1888428 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1227483 Halorubrum litoreum JCM 13561 Archaea 445814826 EMA64784.1 M0P5H1 M0P5H1_9EURY 446 478 yes 1888429 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1407649 Pseudomonas aeruginosa, Pseudomonas aeruginosa RB Bacteria UP000065817, UP000030691 662087578, 619866806 WP_030047190.1 627 627 yes 1888430 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1189620 Flavobacterium sp. ACAM 123 Bacteria 515555679 WP_016988584.1 607 607 yes 1888431 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717, 698962 Corynebacterium diphtheriae, Corynebacterium diphtheriae 31A Bacteria UP000033584, UP000007869 504082098, 371577046 AEX40714.1 WP_014316092.1 fig|698962.3.peg.30 592 599 yes 1888432 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 587753, 1037915, 86192 Pseudomonas chlororaphis, Pseudomonas chlororaphis O6, Pseudomonas chlororaphis subsp. aurantiaca Bacteria UP000027603, UP000003790, UP000029496 496337492, 647802605, 388549846, 692341405 AIC17689.1, EIM13118.1, AIS15322.1 WP_009046670.1 628 629 yes 1888433 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2265, 523849 Thermococcus litoralis, Thermococcus litoralis DSM 5473 Archaea UP000015502 490168951, 374742538 EHR78929.1 WP_004067594.1 H3ZM81 H3ZM81_THELN 429 429 yes 1888434 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262929 Prevotella sp. CAG:520 Environmental samples UP000018359 524350798 527 527 yes 1888435 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81408 Geobacillus caldoxylosilyticus Bacteria 516003760 WP_017434343.1 572 573 yes 1888436 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263004 Firmicutes bacterium CAG:137 Environmental samples UP000018011 524379802 437 437 yes 1888437 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47951 Vibrio cyclitrophicus Bacteria 515155105 WP_016783727.1 640 649 yes 1888438 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 192, 1064539 Azospirillum brasilense, Azospirillum brasilense Sp245 Bacteria UP000065707, UP000007319 504006290, 356877220 WP_014240284.1 605 613 yes 1888439 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1275974 Salmonella enterica, Salmonella enterica subsp. enterica serovar Newport str. SH111077 Bacteria UP000054489, UP000011768 487660173, 459466726 EMG61412.1 WP_001750988.1 fig|1275974.3.peg.4802 626 631 yes 1888440 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386098, 948458 Actinotalea ferrariae, Cellulomonas sp. Mn5-4 Bacteria UP000019753 736094965, 601041450 EYR62398.1 WP_034228037.1 555 561 yes 1888441 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1689, 473819, 1150423 Bifidobacterium dentium, Bifidobacterium dentium ATCC 27678, Bifidobacterium dentium JCM 1195 Bacteria UP000005585, UP000035702 489936034, 171278076, 757806725 EDT45737.1 WP_003839342.1 fig|401473.3.peg.1516, fig|473819.7.peg.1347 581 855 yes 1888442 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 270250, 1094556 Bartonella rattimassiliensis, Bartonella rattimassiliensis 15908 Bacteria UP000001077 494588431, 395420359 EJF86640.1 WP_007347027.1 fig|1094556.3.peg.834 598 606 yes 1888443 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2221, 1090322 Methanolobus tindarius, Methanolobus tindarius DSM 2278 Archaea 564600329, 563512920 ETA68294.1 WP_023845429.1 W9DPL8 W9DPL8_METTI 428 429 yes 1888444 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47951 Vibrio cyclitrophicus Bacteria 515162404 WP_016790957.1 640 649 yes 1888445 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169158 Streptomyces sp. CNS615 Bacteria 516571229 WP_017946293.1 591 595 yes 1888446 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33059, 990288 Acidithiobacillus caldus, Acidithiobacillus caldus SM-1 Bacteria UP000006135 503769278, 340557181 AEK58935.1 WP_014003354.1 fig|990288.8.peg.2257 619 620 yes 1888447 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 542, 627344 Zymomonas mobilis, Zymomonas mobilis subsp. mobilis ATCC 29191 Bacteria UP000009006 504661846, 395397600 AFN56927.1 WP_014848948.1 fig|627344.8.peg.1167 602 604 yes 1888448 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 911241 Pseudomonas sp. CF161 Bacteria UP000014867 520812454, 515456223 EPL04568.1 WP_020299465.1 628 629 yes 1888449 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1325331 Moorella thermoacetica Y72 Bacteria UP000063718 586912293 434 435 yes 1888450 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29549, 518766 Rhodothermus marinus, Rhodothermus marinus DSM 4252 Bacteria UP000002221 502605488, 262333190 ACY46987.1 WP_012842599.1 fig|518766.5.peg.1091 626 627 yes 1888451 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1085386 Bacillus cereus, Bacillus cereus VDM021 Bacteria UP000036076, UP000014039 507061552, 500555295 EOQ19443.1 WP_016132412.1 fig|1085386.3.peg.300 586 586 yes 1888452 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446546 Escherichia coli, Escherichia coli O118:H16 str. 06-3612 Bacteria UP000036210, UP000024012 693142980, 606932879 EYZ65382.1 WP_032283187.1 626 631 yes 1888453 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 190 Aquaspirillum serpens Bacteria 550893032 WP_022653817.1 635 636 yes 1888454 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 102897 Frankia sp. EUN1f Bacteria UP000004777 288345257 EFC79658.1 583 627 yes 1888455 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314282 Psychromonas sp. CNPT3 Bacteria UP000010320 505278972, 469771914 AGH82195.1 WP_015466074.1 642 658 yes 1888456 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053211, 1053217, 718221 Bacillus cereus, Bacillus cereus HuB4-4, Bacillus cereus K-5975c, Bacillus cereus str. Schrouff Bacteria UP000036076, UP000014009, UP000013995, UP000013992 506986754, 500514726, 500374807, 500281219 EOP80518.1, EOO91398.1, EOO06019.1 WP_016078170.1 fig|1053211.3.peg.5889, fig|1053217.3.peg.352, fig|718221.3.peg.4565 586 586 yes 1888457 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 516788184 WP_018101852.1 595 597 yes 1888458 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 112509 Hordeum vulgare subsp. vulgare Plants UP000011116 326509459 283 368 no 1888459 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 225937 marine bacterium HP15 Bacteria UP000007077 311693344 ADP96217.1 fig|225937.3.peg.458 625 631 yes 1888460 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1225184 Pantoea sp. A4 Bacteria 515919488 WP_017350071.1 632 640 yes 1888461 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 517296239 WP_018485057.1 602 608 yes 1888462 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28182, 1001593 Leptospira noguchii, Leptospira noguchii str. 2006001870 Bacteria UP000001344 490560236, 410783302 EKR72299.1 WP_004425295.1 443 496 yes 1888463 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1161409 Bifidobacterium sp. MSTE12 Bacteria UP000018909 736506201, 570841903 ETO95686.1 WP_034522286.1 581 855 yes 1888464 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262874 Eggerthella sp. CAG:1427 Environmental samples UP000018393 546872544, 524024599 WP_021900277.1 445 448 yes 1888465 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 374838, 314283 Reinekea blandensis, Reinekea blandensis MED297 Bacteria UP000005953 495320820, 88778781 EAR09971.1 WP_008045566.1 fig|314283.3.peg.1948 618 628 yes 1888466 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1119528 Methyloversatilis sp. FAM1 Bacteria 519010175 WP_020166050.1 638 638 yes 1888467 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83406 gamma proteobacterium HdN1 Bacteria UP000002677 503027892, 301798167 WP_013262868.1 fig|83406.3.peg.3065 626 626 yes 1888468 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262877 Eggerthella sp. CAG:368 Environmental samples UP000018088 547982870, 524656003 WP_022370141.1 175 177 no 1888469 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1169365, 1181758 Escherichia coli, Escherichia coli KTE232, Escherichia coli KTE212 Bacteria UP000036210, UP000010705, UP000010635 486191701, 431686532, 431012876 ELJ52097.1, ELD26630.1 WP_001544263.1 fig|1181758.3.peg.4367, fig|1169365.3.peg.4229 626 631 yes 1888470 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 520 707 yes 1888471 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263043 Bacteroides eggerthii CAG:109 Environmental samples UP000018152 547198725, 524074972 WP_021939955.1 561 562 yes 1888472 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 123783, 1227493 Natrialba hulunbeirensis, Natrialba hulunbeirensis JCM 10989 Archaea 493704330, 445635989 ELY89154.1 WP_006654052.1 L9ZS26 L9ZS26_9EURY 453 491 yes 1888473 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116125 Escherichia coli, Escherichia coli 2845650 Bacteria UP000036210, UP000012333 487568304, 476193739 EMW14282.1 WP_001719264.1 fig|1116125.3.peg.4705 626 631 yes 1888474 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 1400149 Enterobacter cloacae, Enterobacter cloacae UCI 30 Bacteria UP000036177, UP000020787 695745834, 578210430 EUL70642.1 WP_032672125.1 626 631 yes 1888475 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 948, 1359151, 1359155, 1359159, 1217107 Anaplasma phagocytophilum, Anaplasma phagocytophilum str. Annie, Anaplasma phagocytophilum str. ApWI1, Anaplasma phagocytophilum str. HGE2, Anaplasma phagocytophilum HGE1 Bacteria UP000033356, UP000033460, UP000033622, UP000033456, UP000053959 800916370, 788131135, 788115972, 788114574, 482613185 KJZ98189.1, KJV99010.1, KJV84153.1, KJV82777.1, EOA60924.1 555 555 yes 1888476 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615 Serratia marcescens Bacteria UP000055021 515496167 WP_016929421.1 632 647 yes 1888477 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 469602 Fusobacterium nucleatum, Fusobacterium sp. 3_1_27 Bacteria UP000005137 496072237, 294486432 EFG33794.1 WP_008796744.1 433 433 yes 1888478 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 69042 Synechococcus sp. WH 5701 Bacteria UP000002935 87283554 EAQ75509.1 293 293 no 1888479 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1264, 246199 Ruminococcus albus, Ruminococcus albus 8 Bacteria UP000004259 488942279, 324106903 EGC01193.1 WP_002853354.1 437 437 yes 1888480 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 342108 Magnetospirillum magneticum AMB-1 Bacteria UP000007058 82944161 Q2WAV0 THIC_MAGSA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1101142 fig|342108.5.peg.221 608 648 yes 1888481 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1260, 1459804 Finegoldia magna, Finegoldia magna ALB8 Bacteria UP000021736 737123356, 588298586 EXF27920.1 WP_035111028.1 433 433 yes 1888482 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 275 275 no 1888483 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 75697, 1437824 Castellaniella defragrans, Castellaniella defragrans 65Phen Bacteria UP000019805 760001628, 589268072 WP_043685116.1 635 637 yes 1888484 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317, 1324932, 321, 591153, 1262350 Pseudomonas syringae, Pseudomonas syringae pv. syringae HS191, Pseudomonas syringae pv. syringae, Pseudomonas syringae pv. syringae FF5, Pseudomonas syringae pv. syringae SM Bacteria UP000028642, UP000034641, UP000028706, UP000028163, UP000014579 498093340, 817568811, 671770086, 666931995, 514083949 AKF49396.1, KFF81250.1, KEZ74881.1, EPF64684.1 WP_010407496.1 627 629 yes 1888485 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 201089 uncultured Desulfobacterium sp. Environmental samples 308271797 434 440 yes 1888486 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 327160, 522306 Candidatus Accumulibacter phosphatis, Candidatus Accumulibacter phosphatis clade IIA str. UW-1 Bacteria UP000001619 502499779, 257044217 ACV33405.1 WP_012806862.1 fig|522306.3.peg.282 638 638 yes 1888487 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 905, 591001 Acidaminococcus fermentans, Acidaminococcus fermentans DSM 20731 Bacteria UP000001902 502702591, 283952088 ADB46891.1 WP_012937881.1 fig|591001.3.peg.517 435 435 yes 1888488 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 936572 Selenomonas sp. FOBRC6 Bacteria UP000006984 497341447, 400189040 EJO23161.1 WP_009655660.1 fig|936572.3.peg.653 432 434 yes 1888489 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68202, 1303692 Streptomyces fulvissimus, Streptomyces fulvissimus DSM 40593 Bacteria UP000013304 505422783, 485095350 AGK78533.1 WP_015609885.1 fig|1303692.3.peg.3632 591 600 yes 1888490 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61435, 311424 Dehalococcoides ethenogenes, Dehalococcoides sp. VS Bacteria UP000054393, UP000002506 502645620, 270153980 ACZ61818.1 WP_012881976.1 fig|311424.5.peg.648 430 431 yes 1888491 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 469607 Fusobacterium nucleatum, Fusobacterium sp. 4_8 Bacteria UP000014361 511279026, 506960107 AGM24475.1 WP_016340114.1 fig|469607.3.peg.2042 433 433 yes 1888492 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1208664 Cronobacter sakazakii 696 Bacteria UP000009356 423237747 438 441 yes 1888493 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 517281449 WP_018470267.1 595 597 yes 1888494 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1282360 Asticcacaulis sp. AC460 Bacteria UP000017839 557823862, 557352529 ESQ92037.1 WP_023452128.1 610 613 yes 1888495 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 392734, 926566 Terriglobus roseus, Terriglobus roseus DSM 18391 Bacteria UP000006056 504598316, 390412345 AFL87849.1 WP_014785418.1 fig|926566.3.peg.1527 483 493 yes 1888496 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1304866 Clostridium sp. ASBs410 Bacteria UP000020295 643554884, 589398727 EXG83453.1 WP_025229876.1 434 435 yes 1888497 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1229521 Nitrincola sp. AK23 Bacteria UP000019464 738603949, 589826747 EXJ09262.1 WP_036514398.1 625 626 yes 1888498 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410619 Serratia sp. DD3 Bacteria UP000017810 558559798, 666390269 KEY57469.1 WP_023490716.1 638 652 yes 1888499 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1282363 Asticcacaulis sp. YBE204 Bacteria UP000017808 557340280 ESQ80006.1 618 622 yes 1888500 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263042 Bacteroides dorei CAG:222 Environmental samples UP000018210 547773720, 524387027 WP_022185082.1 565 565 yes 1888501 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 406552 Natrinema sp. J7 Archaea UP000006507 504678341, 397775519, 397684612 AFO58989.1 WP_014865443.1, YP_006543065.1 I7CMG3 I7CMG3_NATSJ 456 481 yes 1888502 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310703 Acinetobacter baumannii, Acinetobacter baumannii 1417041 Bacteria UP000028632, UP000021020 691108181, 588247006 EXF18726.1 WP_032030855.1 621 625 yes 1888503 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 200 Campylobacter curvus Bacteria 516864035 WP_018136228.1 443 444 yes 1888504 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 420950, 1094980 Methanolobus psychrophilus, Methanolobus psychrophilus R15 Archaea UP000000459 504865591, 409169095 AFV22970.1 WP_015052693.1 K4MA22 K4MA22_9EURY 429 429 yes 1888505 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1423 Bacillus subtilis Bacteria UP000030083 518685078 WP_019846771.1 201 201 no 1888506 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 446 447 yes 1888507 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 95641 Methylomicrobium buryatense Bacteria 516451966 WP_017840878.1 621 622 yes 1888508 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1382595 Saccharopolyspora erythraea D Bacteria UP000015795 531066744 EQD82873.1 544 547 yes 1888509 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1049790 Leptospira inadai serovar Lyme str. 10 Bacteria UP000018719 529313977 EQA37707.1 524 526 yes 1888510 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 278963 Acidobacteriaceae bacterium TAA166 Bacteria 551216771 WP_022844713.1 488 493 yes 1888511 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 80867 Acidovorax avenae Bacteria 518530675 WP_019700882.1 614 617 yes 1888512 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1131291 Gallionella sp. SCGC AAA018-N21 Bacteria 517104053 WP_018292871.1 623 623 yes 1888513 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1147684, 477184 Achromobacter arsenitoxydans, Achromobacter sp. SY8 Bacteria UP000003113 495442261, 359362056 EHK63801.1 WP_008166955.1 fig|477184.5.peg.4589 636 637 yes 1888514 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 169679, 1345695 Clostridium saccharobutylicum, Clostridium saccharobutylicum DSM 13864 Bacteria UP000017118 550999327, 549807843 AGX41749.1 WP_022744036.1 436 436 yes 1888515 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 536, 243365 Chromobacterium violaceum, Chromobacterium violaceum ATCC 12472 Bacteria UP000036475, UP000001424 499446326, 34101545, 47606112 AAQ57914.1 WP_011133790.1 Q7P1H8 THIC_CHRVO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 515386 fig|243365.1.peg.235 631 632 yes 1888516 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 638849, 352165 Pyramidobacter piscolens, Pyramidobacter piscolens W5455 Bacteria UP000006462 496454675, 282586791 EFB92035.1 WP_009163520.1 436 437 yes 1888517 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380770 Streptomycetaceae bacterium MP113-05 Bacteria UP000017915 558873731, 558546847 EST37503.1 WP_023529424.1 619 622 yes 1888518 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 381852, 1227461 Haloferax prahovense, Haloferax prahovense DSM 18310 Archaea 495371511, 445713931 ELZ65704.1 WP_008096224.1 M0G4H4 M0G4H4_9EURY 436 465 yes 1888519 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1501433, 272129 Oscillatoria sp. PCC 6506 Bacteria UP000004532 494598211, 300334556 WP_007356465.1 452 456 yes 1888520 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 195, 1358410, 306254 Campylobacter coli, Campylobacter coli 15-537360, Campylobacter coli RM2228 Bacteria UP000062643, UP000017741, UP000005423 488866220, 556029839, 57020094 AGZ20920.1, EAL56771.1 WP_002778459.1 fig|306254.1.peg.950 429 430 yes 1888521 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1427518 Xenorhabdus szentirmaii DSM 16338 Bacteria UP000019202 575847387 625 758 yes 1888522 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 665943 Eggerthella sp. 1_3_56FAA Bacteria UP000005705 316911067 EFV32679.1 431 432 yes 1888523 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1002364 Hafnia alvei ATCC 51873 Bacteria UP000005959 364570536 EHM48145.1 fig|1002364.3.peg.274 590 597 yes 1888524 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158146 Thioalkalivibrio sp. ALJT Bacteria 518455053 WP_019625260.1 627 629 yes 1888525 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36746, 1441629 Pseudomonas cichorii, Pseudomonas cichorii JBC1 Bacteria UP000019031 643802967, 572999341 AHF65684.1 WP_025258270.1 627 629 yes 1888526 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265072 Methylobacillus flagellatus KT Bacteria UP000002440 91710867 ABE50795.1 fig|265072.11.peg.2651 625 628 yes 1888527 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1402, 1348578 Bacillus licheniformis, Bacillus licheniformis S 16 Bacteria UP000036721, UP000019271 763043396, 584582290 EWH21640.1 WP_043927290.1 591 591 yes 1888528 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2173, 521002 Methanobrevibacter smithii, Methanobrevibacter smithii DSM 2374 Archaea 490132031, 288861614 EFC93912.1 WP_004032401.1 D2ZN94 D2ZN94_METSM 423 424 yes 1888529 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444135 Escherichia coli, Escherichia coli 1-250-04_S3_C1 Bacteria UP000036210, UP000024043 693151034, 611079721 EZJ81473.1 WP_032288373.1 626 631 yes 1888530 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 751585 Coprococcus sp. ART55/1 Bacteria UP000008799 295093711 435 436 yes 1888531 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1239307 Enterobacteriaceae bacterium HS Bacteria UP000019028 645052726, 573023347 AHF78883.1 WP_025424007.1 628 642 yes 1888532 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 889242 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni LMG 23263 Bacteria UP000065538, UP000003338 488962526, 380606223 EIB26144.1 WP_002873550.1 fig|889242.3.peg.1010 430 430 yes 1888533 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1005043 Candidatus Regiella insecticola R5.15 Bacteria UP000004116 347604378 EGY29045.1 397 412 no 1888534 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 310300, 1235809 Bacteroides pyogenes, Bacteroides pyogenes JCM 6292 Bacteria UP000018861 653074982, 567763916 WP_027326051.1 563 563 yes 1888535 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 437, 1231351 Acidomonas methanolica, Acidomonas methanolica NBRC 104435 Bacteria UP000019760 754678793, 602596611 WP_042058718.1 600 612 yes 1888536 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1777, 1436723 Mycobacterium gastri, Mycobacterium gastri 'Wayne' Bacteria UP000019111 738468118, 574757842 ETW21798.1 WP_036418658.1 544 546 yes 1888537 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 701176 Vibrio sp. N418 Bacteria UP000003627 496855847, 342796704 EGU32377.1 WP_009386798.1 640 645 yes 1888538 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53358, 710696 Intrasporangium calvum, Intrasporangium calvum DSM 43043 Bacteria UP000008914 503257569, 315588617 ADU47914.1 WP_013492230.1 fig|710696.3.peg.1421 570 570 yes 1888539 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1164, 551115 Anabaena azollae, 'Nostoc azollae' 0708 Bacteria UP000001511 502957527, 298234355 ADI65491.1 WP_013192503.1 fig|551115.6.peg.5215 455 457 yes 1888540 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 993047 Rhizobium etli CNPAF512 Bacteria UP000003712 327191122 EGE58168.1 fig|993047.3.peg.3560 272 293 no 1888541 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 526226 Gordonia bronchialis DSM 43247 Bacteria UP000001219 262084008 ACY19976.1 fig|526226.5.peg.4191 552 568 yes 1888542 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 651, 1208104 Aeromonas media, Aeromonas media WS Bacteria UP000006592 491473258, 615554531 AHX63576.1 WP_005331009.1 645 664 yes 1888543 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2203, 323259 Methanospirillum hungatei, Methanospirillum hungatei JF-1 Archaea UP000001941 499768683, 88189162 ABD42159.1 WP_011449417.1 Q2FNA7 Q2FNA7_METHJ fig|323259.5.peg.2585 405 424 no 1888544 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1261, 1035196, 1263100 Peptostreptococcus anaerobius, Peptostreptococcus anaerobius VPI 4330, Peptostreptococcus anaerobius CAG:621 Bacteria, Environmental samples UP000010423, UP000018261 488934466, 429151306, 524067408 EKX94176.1 WP_002845541.1 fig|1035196.3.peg.507, fig|1122950.3.peg.1806 436 436 yes 1888545 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1412601 Salmonella enterica, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120051 Bacteria UP000054489, UP000023674 740607612, 603435607 AHS42840.1 WP_038393145.1 625 631 yes 1888546 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262943 Roseburia sp. CAG:197 Environmental samples UP000018336 547465743, 524261516 WP_022084781.1 435 436 yes 1888547 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310594, 1094482, 1224165, 1094469, 903936, 992402 Acinetobacter baumannii, Acinetobacter baumannii 653020, Acinetobacter baumannii ABNIH18, Acinetobacter baumannii ABNIH25, Acinetobacter baumannii ABNIH5, Acinetobacter baumannii Naval-78, Acinetobacter baumannii ABNIH1 Bacteria UP000028632, UP000021806, UP000012195, UP000012250, UP000012397, UP000011504, UP000005497 446995610, 588078372, 475964526, 475915378, 475914779, 444776134, 342226575 EXD58880.1, EMU30487.1, EMT85331.1, EMT84752.1, ELX00185.1, EGT91539.1 WP_001072866.1 fig|1224165.3.peg.2578, fig|903936.3.peg.1205, fig|1094469.3.peg.3222, fig|1094482.3.peg.1525, fig|992402.3.peg.2344 621 625 yes 1888548 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1316941, 387631 Archaeoglobus sulfaticallidus, Archaeoglobus sp. PM70-1 Archaea UP000013307 505404112, 484592973 AGK61616.1 WP_015591214.1 N0BM09 N0BM09_9EURY 425 425 yes 1888549 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1218600 Leptospira sp. P2653 Bacteria UP000011921 523648213, 463290927 EMJ60310.1 WP_020782878.1 fig|1218600.3.peg.4368 487 487 yes 1888550 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 485, 528355 Neisseria gonorrhoeae, Neisseria gonorrhoeae PID1 Bacteria UP000027314, UP000003985 489793950, 268586719, 800571624 EEZ51395.1 WP_003697841.1 624 633 yes 1888551 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 263511, 423471, 423472, 423474, 555881 Crocosphaera watsonii, Crocosphaera watsonii WH 0003, Crocosphaera watsonii WH 0005, Crocosphaera watsonii WH 8502, Crocosphaera watsonii WH 0401 Bacteria UP000003477, UP000017981, UP000018348, UP000018198 494519886, 357265838, 543526344, 543518065, 543431527 EHJ14550.1 WP_007309340.1 fig|423471.3.peg.701 459 459 yes 1888552 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 831 Butyrivibrio fibrisolvens Bacteria 551013807 WP_022758188.1 436 437 yes 1888553 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 202954, 1120927 Acinetobacter tandoii, Acinetobacter tandoii DSM 14970 = CIP 107469 Bacteria UP000016201 507097831, 505760314 EOR04387.1 WP_016168468.1 626 631 yes 1888554 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 182210, 643562 Desulfovibrio aespoeensis, Desulfovibrio aespoeensis Aspo-2 Bacteria UP000002191 503279555, 316943234 ADU62285.1 WP_013514216.1 fig|643562.5.peg.2277 434 434 yes 1888555 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1127134 Nocardia cyriacigeorgica GUH-2 Bacteria UP000008190 374848807 fig|135487.3.peg.5164 550 553 yes 1888556 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76831, 883155, 929704 Myroides odoratimimus CIP 103059, Myroides odoratus DSM 2801 Bacteria UP000005393, UP000005785 489077871, 404610108, 373910397 EKB09464.1, EHQ42246.1 WP_002987813.1 fig|929704.3.peg.1388, fig|883155.3.peg.83 605 605 yes 1888557 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 596 673 yes 1888558 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 541 590 no 1888559 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 38284, 862512 Corynebacterium accolens, Corynebacterium accolens ATCC 49726 Bacteria UP000004599 491424965, 304568107 EFM43681.1 WP_005282760.1 620 643 yes 1888560 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 566461 Streptomyces ghanaensis ATCC 14672 Bacteria UP000003824 491127591, 291341465 EFE68421.1 WP_004986024.1 601 604 yes 1888561 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444091, 1116071, 1116108, 1116119, 1116066 Escherichia coli, Escherichia coli 6-537-08_S1_C2, Escherichia coli P0301867.8, Escherichia coli 178900, Escherichia coli 2719100, Escherichia coli P0301867.1 Bacteria UP000036210, UP000028153, UP000012285, UP000012245, UP000012319, UP000012388 447199673, 660251724, 477001503, 476753265, 476364376, 476297830 KEN42436.1, ENC87562.1, ENA57282.1, EMX81561.1, EMX15765.1 WP_001276929.1 fig|1116119.3.peg.4934, fig|913088.3.peg.936, fig|1116066.3.peg.4922, fig|1116071.3.peg.4507, fig|1116108.3.peg.4602 626 631 yes 1888562 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1182718, 1089445 Escherichia coli, Escherichia coli KTE135, Escherichia coli AI27 Bacteria UP000036210, UP000010683, UP000006412 447199676, 730016575, 431381921, 384469695 KHJ05062.1, ELG66272.1, EIE53841.1 WP_001276932.1 fig|1182718.3.peg.1425, fig|1089445.3.peg.4038 626 631 yes 1888563 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1268976, 1281188, 656419 Escherichia coli, Escherichia coli 113290, Escherichia coli UMEA 3124-1, Escherichia coli M718 Bacteria UP000036210, UP000017268, UP000016308, UP000002790 447199677, 669338753, 553346608, 535543877, 331046619 KFD78724.1, ESA73913.1, EQW82040.1, EGI18706.1 WP_001276933.1 626 631 yes 1888564 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 620, 624, 766143 Shigella sonnei, Shigella dysenteriae 225-75 Bacteria UP000054188, UP000004059 447199679, 821335243, 391298399 AKH28454.1, EIQ56408.1 WP_001276935.1 fig|766143.3.peg.4301 626 631 yes 1888565 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 490 Neisseria sicca Bacteria 518100519 WP_019270727.1 143 143 3EPO, 3EPN, 4S2A no 1888566 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454003 Candidatus Accumulibacter sp. BA-92 Bacteria UP000021816 754980251, 589605700 EXI77434.1 WP_042335860.1 638 638 yes 1888567 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1230476 Bradyrhizobium sp. DFCI-1 Bacteria UP000016507 544645660, 540135053 ERF81068.1 WP_021079982.1 622 632 yes 1888568 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 136849, 53409, 563797 Pseudomonas coronafaciens, Pseudomonas syringae pv. oryzae str. 1_6 Bacteria UP000031801, UP000005313 492567958, 705520804, 331027215, 331021099 KGS14825.1, EGI07270.1, EGI01156.1 WP_005888462.1 628 629 yes 1888569 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262916 Porphyromonas sp. CAG:1061 Environmental samples UP000018064 546919984, 524027148 WP_021903615.1 523 523 yes 1888570 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1147786 Pseudomonas mandelii JR-1 Bacteria UP000026913 635287300 AHZ70045.1 628 630 yes 1888571 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 342949 Pyrococcus sp. NA2 Archaea UP000008293 503513079, 331033200 AEC51012.1 WP_013747570.1 F4HI85 F4HI85_PYRSN 428 428 yes 1888572 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1470590 Stenotrophomonas sp. RIT309 Bacteria UP000024193 696405439, 612086057 EZP44720.1 WP_032976762.1 613 614 yes 1888573 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1260, 866773 Finegoldia magna, Finegoldia magna BVS033A4 Bacteria UP000003807 488928121, 302495039 EFL54792.1 WP_002839196.1 433 433 yes 1888574 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413889, 632348 Caldicellulosiruptor kronotskyensis, Caldicellulosiruptor kronotskyensis 2002 Bacteria UP000006835 503196498, 312203761 ADQ47088.1 WP_013431159.1 fig|632348.3.peg.2373 419 420 yes 1888575 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 88431, 1263074 Dorea longicatena, Dorea longicatena CAG:42 Bacteria, Environmental samples UP000018333 548194964, 524710912 WP_022415567.1 435 436 yes 1888576 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39778, 1403949 Veillonella dispar, Veillonella dispar DORA_11 Bacteria UP000018855 568111001, 566236453 ETI98191.1 WP_024061420.1 434 434 yes 1888577 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 216592 Escherichia coli, Escherichia coli 042 Bacteria UP000036210, UP000001407 446039459, 284924086 WP_000117314.1 fig|216592.1.peg.2277 626 631 yes 1888578 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116083 Escherichia coli, Escherichia coli P0305260.9 Bacteria UP000036210, UP000012392 487384045, 477360645 ENG29214.1 WP_001656145.1 fig|1116083.3.peg.4226 626 631 yes 1888579 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 267375, 1117316 Pseudoalteromonas marina, Pseudoalteromonas marina mano4 Bacteria UP000016528 498241484, 540269407 ERG27644.1 WP_010555640.1 645 650 yes 1888580 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1394889 Thermosynechococcus sp. NK55 Bacteria UP000018741 564737070 AHB87468.1 459 461 yes 1888581 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262998 Firmicutes bacterium CAG:102 Environmental samples UP000018112 512174766, 511540914 WP_016406756.1 433 434 yes 1888582 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1166130 Enterobacter sp. R4-368 Bacteria UP000014269 521291798, 511529123 AGN86663.1 WP_020456066.1 fig|1166130.5.peg.3151 626 630 yes 1888583 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262782 Clostridium sp. CAG:230 Environmental samples UP000017961 547727298, 524331834 WP_022141475.1 434 435 yes 1888584 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 293, 1035191 Brevundimonas diminuta, Brevundimonas diminuta 470-4 Bacteria UP000010410 489259278, 429187881 EKY28782.1 WP_003167178.1 fig|1035191.3.peg.1368 618 636 yes 1888585 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 62322, 693971, 693974 Shewanella baltica, Shewanella baltica OS183, Shewanella baltica BA175 Bacteria UP000005122, UP000002249 492993192, 373886226, 333818683 EHQ15118.1, AEG11349.1 WP_006081761.1 655 707 yes 1888586 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1402491 Pseudomonas aeruginosa, Pseudomonas aeruginosa CF5 Bacteria UP000065817, UP000017303 553799888, 552706283 ERZ19734.1 WP_023130362.1 628 636 yes 1888587 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53633, 679936, 1051632 Sulfobacillus acidophilus, Sulfobacillus acidophilus DSM 10332, Sulfobacillus acidophilus TPY Bacteria UP000005439, UP000000291 503754409, 361053280, 339287660 AEW04797.1, AEJ41771.1 WP_013988485.1 fig|679936.5.peg.1363, fig|1051632.4.peg.3529 574 576 yes 1888588 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 165, 907348 Treponema saccharophilum, Treponema saccharophilum DSM 2985 Bacteria UP000003571 488792505, 380767578 EIC01578.1 WP_002704911.1 fig|907348.3.peg.1830 441 442 yes 1888589 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2369 Arhodomonas aquaeolei Bacteria 517547031 WP_018717239.1 623 626 yes 1888590 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2246, 309800 Haloferax volcanii, Haloferax volcanii DS2 Archaea UP000011532 490141693, 445579351 ELY33746.1 WP_004042037.1 L9V9T8 L9V9T8_HALVD 437 465 yes 1888591 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111105 Porphyromonas gulae Bacteria UP000029876 517795739 WP_018965947.1 587 587 yes 1888592 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 237610, 1112217 Pseudomonas psychrotolerans, Pseudomonas psychrotolerans L19 Bacteria UP000004220 494281305, 359369022 EHK69596.1 WP_007162105.1 fig|1112217.3.peg.3673 625 625 yes 1888593 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 214851, 411471 Subdoligranulum variabile, Subdoligranulum variabile DSM 15176 Bacteria UP000003438 494104820, 282571818 EFB77353.1 WP_007045606.1 436 436 yes 1888594 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358 Agrobacterium tumefaciens Bacteria UP000064781 737237736, 635307468 WP_035222065.1 600 607 yes 1888595 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33047, 1094562 Bartonella vinsonii, Bartonella vinsonii subsp. arupensis OK-94-513 Bacteria UP000002304 491003015, 395420741 EJF87003.1 WP_004864736.1 fig|1094562.3.peg.1360 602 611 yes 1888596 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29494, 903510 Vibrio furnissii, Vibrio furnissii NCTC 11218 Bacteria UP000051221, UP000007456 503970208, 315178676 ADT85590.1 WP_014204202.1 fig|903510.3.peg.346 640 649 yes 1888597 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1392998 Candidatus Methanoperedens nitroreducens Archaea 851159864, 630830262 KCZ71974.1 WP_048091072.1 A0A062V898 A0A062V898_9EURY 405 409 no 1888598 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1951 Streptomyces purpureus Bacteria 518727618 WP_019887803.1 589 590 yes 1888599 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40215, 1330047, 1217664, 1217666 Acinetobacter junii, Acinetobacter junii MTCC 11364, Acinetobacter junii CIP 64.5, Acinetobacter junii CIP 107470 Bacteria UP000018420, UP000018462, UP000013082 491055342, 523903780, 480027776, 480007285 EPR86067.1, ENV68292.1, ENV49104.1 WP_004916989.1 fig|1217666.3.peg.3485, fig|1217664.3.peg.73 626 631 yes 1888600 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 657316 Megamonas hypermegale ART12/1 Bacteria UP000008806 291534214 61 61 no 1888601 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 657316 Megamonas hypermegale ART12/1 Bacteria UP000008806 291534213 344 349 no 1888602 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 579922, 1189612 Indibacter alkaliphilus, Indibacter alkaliphilus LW1 Bacteria UP000006073 510936767, 509708584 EOZ92857.1 WP_016255520.1 626 626 yes 1888603 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 296543 Thalassiosira pseudonana CCMP1335 Plants 224006700, 220971952 EED90285.1 XP_002292310.1 549 636 yes 1888604 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 38304, 553206 Corynebacterium tuberculostearicum, Corynebacterium tuberculostearicum SK141 Bacteria UP000004384 491471225, 255297947 EET77258.1 WP_005328979.1 fig|553206.4.peg.1664 588 593 yes 1888605 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 631362 Thiorhodovibrio sp. 970 Bacteria UP000002964 496441209, 380877557 EIC19649.1 WP_009150054.1 626 634 yes 1888606 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53413, 1085630 Xanthomonas axonopodis, Xanthomonas axonopodis pv. punicae str. LMG 859 Bacteria UP000054035, UP000006256 492704240, 372554153 WP_005928675.1 fig|1085630.3.peg.2035 624 625 yes 1888607 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1145276 Lysinibacillus sp. GY32 Bacteria UP000019675 643489550, 597826647 AHN20200.1 WP_025218383.1 592 592 yes 1888608 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1173263 Synechococcus sp. PCC 7502 Bacteria UP000010385 504980707, 427994455 AFY73150.1 WP_015167809.1 fig|1173263.3.peg.1072 454 458 yes 1888609 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 365348, 1122947, 1149860, 1149862 Pelosinus fermentans DSM 17108, Pelosinus fermentans A11, Pelosinus fermentans B4 Bacteria UP000004072, UP000003885, UP000004324 495207134, 392451937, 392443763, 392442281 EIW28906.1, EIW21272.1, EIW19871.1 WP_007931915.1 fig|1149859.3.peg.1255, fig|1149862.3.peg.1023, fig|1122947.3.peg.3727, fig|1235479.3.peg.1323, fig|1149861.3.peg.4461, fig|1149860.3.peg.4660 432 432 yes 1888610 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 991947 Vibrio cholerae, Vibrio cholerae HE48 Bacteria UP000028983, UP000005576 445993257, 340049664 EGR10577.1 WP_000071112.1 fig|991947.6.peg.84 639 645 yes 1888611 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 257313, 520, 1403053, 743278, 743277, 1460381, 1458277, 1331275, 1331269, 1331274, 1331280, 1331279, 1331278, 1331276, 1331273, 1331263, 1331285, 1331272, 1331271, 1331270, 1331266, 1331267, 1331265, 1331264, 1331284, 1331283, 1331282, 1331281, 1331253, 1331252, 1331249, 1331248, 1331247, 1420596, 1017264, 568706 Bordetella pertussis Tohama I, Bordetella pertussis, Bordetella pertussis 137, Bordetella pertussis B1920, Bordetella pertussis B1917, Bordetella holmesii H934, Bordetella pertussis B200, Bordetella pertussis STO1-CNMC-0004, Bordetella pertussis STO1-SEAT-0004, Bordetella pertussis STO1-CHOM-0012, Bordetella pertussis STO1-CHOC-0021, Bordetella pertussis STO1-CHOC-0019, Bordetella pertussis STO1-CHOC-0018, Bordetella pertussis STO1-CHOC-0016, Bordetella pertussis STO1-CHOC-0008, Bordetella pertussis STO1-CHLA-0011, Bordetella pertussis STO1-CHLA-0006, Bordetella pertussis I176, Bordetella pertussis I036, Bordetella pertussis I002, Bordetella pertussis Bp H921, Bordetella pertussis Bp H939, Bordetella pertussis Bp H918, Bordetella pertussis Bp H897, Bordetella pertussis CHLA-26, Bordetella pertussis CHLA-20, Bordetella pertussis CHLA-15, Bordetella pertussis CHLA-13, Bordetella bronchiseptica SEAT0007, Bordetella bronchiseptica SEAT0006, Bordetella bronchiseptica 2371640, Bordetella bronchiseptica 2356847, Bordetella bronchiseptica 2250905, Bordetella pertussis CHLA-11, Bordetella pertussis CS, Bordetella pertussis 18323 Bacteria UP000002676, UP000061651, UP000030947, UP000031744, UP000025354, UP000025844, UP000018677, UP000018664, UP000018718, UP000018668, UP000018749, UP000018746, UP000018709, UP000018722, UP000018691, UP000018752, UP000018742, UP000018711, UP000018705, UP000018686, UP000018751, UP000018696, UP000018669, UP000018679, UP000018755, UP000018665, UP000018704, UP000018736, UP000018762, UP000018667, UP000018708, UP000018734, UP000019108, UP000008462, UP000062696 33591450, 499232143, 742223738, 719638017, 719633948, 627869788, 627859020, 565800565, 565796671, 565789544, 565787998, 565784459, 565779778, 565770435, 565766973, 565764924, 565759187, 565754735, 565752826, 565747463, 565740342, 565732940, 565729169, 565725341, 565721631, 565718277, 565713729, 565708762, 565704844, 565701023, 565700088, 565696120, 565689287, 563506727, 332380851, 821319853, 811498795, 811492229, 811484306, 811470873, 811464490, 811456461, 811442265, 811434492, 811426586, 811420211, 811411578, 811402997, 811388526, 811381444, 811374213, 811364623, 811356361, 811339706, 811330822, 811322772, 811302068, 811295736, 811287296, 811278965, 811268705, 805185378, 805179996, 805174873, 805169772, 805164915, 805159743, 805154795, 805150059, 805145215, 805140538, 805135824, 805131164, 805126359, 805121645, 805117371, 805112467, 805108122, 805103936, 805099732, 805095925, 803181381, 803173812, 803134607, 803122358, 803108498, 803100098, 803088059, 803077614, 803065258, 803058262, 803045255, 803011223, 802876990, 802865544, 802861138, 802851831, 802846245, 802838892, 802835818, 802813051, 802809047, 802802075, 802757844, 802217735, 802210507, 802195885, 802183820, 802180193, 802171097, 802163619, 802152118, 802147692, 802139954, 802066074, 802062027, 802058575, 802047561, 802037637, 802034162, 802031474, 802022405, 802018761, 802013715, 802008338, 802004621, 802000800, 801995716, 801989899, 801986143, 801983280, 801970149, 801958280, 801955130, 801948863, 801943122, 801939052, 801935268, 801931443, 801915744, 801912517, 801907732, 801903026, 801897151, 801894326, 801889087, 801884680, 801875281, 801870187, 801866552, 801863436, 801858000, 801853460, 801849681, 801839762, 801834353, 801829543, 801825905, 801814503, 801811200, 801807591, 801802932, 801798914, 801787523, 801783702, 801773192, 801769619, 801764734, 801754202, 801744899, 801739397, 801365047, 801359641, 801260344, 800853131, 401776755, 47606133, 33571092 AJB28154.1, AIW94262.1, AIW90801.1, KCV27546.1, KCV18218.1, ETI08054.1, ETI04306.1, ETH97306.1, ETH95777.1, ETH92308.1, ETH87762.1, ETH78648.1, ETH75267.1, ETH73284.1, ETH67597.1, ETH63201.1, ETH61311.1, ETH56019.1, ETH49006.1, ETH41684.1, ETH37970.1, ETH34282.1, ETH30642.1, ETH27365.1, ETH22978.1, ETH18145.1, ETH14263.1, ETH10490.1, ETH09579.1, ETH05808.1, ETG99347.1, ETA63334.1, AEE65698.1 NP_879094.1, WP_010929683.1 Q7W0D7 THIC_BORPE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 511504 fig|568706.3.peg.595, fig|1017264.3.peg.217, fig|743274.3.peg.1608, fig|743273.3.peg.866, fig|257313.1.peg.174, fig|743276.3.peg.3274 635 637 yes 1888612 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1226325 Clostridium sp. KLE 1755 Bacteria UP000016509 545395995, 542970923 ERI68964.1 WP_021636266.1 435 435 yes 1888613 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 442, 290633 Gluconobacter oxydans, Gluconobacter oxydans 621H Bacteria UP000006375 499572947, 58003066, 81556926 AAW61960.1 WP_011253730.1 Q5FNT7 THIC_GLUOX Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 857842 fig|290633.1.peg.2161 593 597 yes 1888614 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 641148, 641149 Neisseria sp. oral taxon 014, Neisseria sp. oral taxon 014 str. F0314 Bacteria UP000002768 496464251, 298282375 EFI23862.1 WP_009173096.1 625 633 yes 1888615 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 530 530 yes 1888616 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262893 Eubacterium sp. CAG:786 Environmental samples UP000018127 547034169, 524038357 WP_021911138.1 318 326 no 1888617 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324, 1163399 Stenotrophomonas maltophilia, Stenotrophomonas maltophilia D457 Bacteria UP000034806, UP000007390 504461228, 384079426 WP_014648330.1 fig|1163399.5.peg.3586 613 614 yes 1888618 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287243 Mesorhizobium sp. LNHC232B00 Bacteria UP000021324 563563081, 563139090 ESY63077.1 WP_023768630.1 596 611 yes 1888619 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1432554 Klebsiella pneumoniae, Klebsiella pneumoniae IS53 Bacteria UP000036212, UP000019203 749506009, 571194753 WP_040146741.1 626 631 yes 1888620 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1260983 Leptospirillum sp. Group IV 'UBA BS' Bacteria UP000017751 530927612 EQD24357.1 158 159 no 1888621 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1015, 883098 Bergeyella zoohelcum, Bergeyella zoohelcum CCUG 30536 Bacteria UP000006089 488764718, 405586436 EKB60205.1 WP_002687918.1 fig|883098.3.peg.1273 607 607 yes 1888622 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 1470557 Streptomyces sp. Tu 6176 Bacteria UP000020060 517392781, 602253621 EYT79969.1 WP_018566262.1 594 596 yes 1888623 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 889228, 889255, 889250 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni 87330, Campylobacter jejuni subsp. jejuni 2008-831, Campylobacter jejuni subsp. jejuni 2008-1025 Bacteria UP000065538, UP000005182, UP000005165, UP000006260 488978803, 691309124, 380654988, 380639871, 380630271 KGF74465.1, EIB71323.1, EIB57340.1, EIB48513.1 WP_002889652.1 fig|889228.3.peg.798, fig|889255.3.peg.468, fig|889250.3.peg.103 430 430 yes 1888624 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 542, 555217 Zymomonas mobilis, Zymomonas mobilis subsp. mobilis ATCC 10988 Bacteria UP000001494 504313542, 335931968 AEH62508.1 WP_014500644.1 602 604 yes 1888625 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 497727, 1237085 Candidatus Nitrososphaera gargensis, Candidatus Nitrososphaera gargensis Ga9.2 Archaea UP000008037 504833504, 408405747, 408366343 AFU60073.1 WP_015020606.1, YP_006863730.1 K0IKZ7 K0IKZ7_NITGG 445 445 no 1888626 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 163869 Algicola sagamiensis Bacteria 517524099 WP_018694307.1 612 614 yes 1888627 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217707 Acinetobacter sp. ANC 3929 Bacteria UP000013159 491296749, 480141793 ENW78961.1 WP_005154762.1 fig|1217707.3.peg.3218 626 631 yes 1888628 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84588 Synechococcus sp. WH 8102 Bacteria UP000001422 47606116, 33632199 Q7U9W2 THIC_SYNPX Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 204101 fig|84588.1.peg.137 467 483 yes 1888629 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1048834 Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1 Bacteria UP000000292 339290739 AEJ44849.1 fig|1048834.4.peg.2812 559 559 yes 1888630 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 247490 planctomycete KSU-1 Bacteria UP000002985 494426258, 386403421 WP_007223112.1 fig|247490.3.peg.3731 424 424 yes 1888631 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43080 Sulfolobus islandicus Archaea 515101507 WP_016730699.1 432 433 yes 1888632 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 859, 1441737, 1441733 Fusobacterium necrophorum, Fusobacterium necrophorum DJ-2, Fusobacterium necrophorum DJ-1 Bacteria UP000027058, UP000027464 737936132, 635320196, 635318790 KDE69298.1, KDE68106.1 WP_035900779.1 433 433 yes 1888633 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 35833, 563192 Bilophila wadsworthia, Bilophila wadsworthia 3_1_6 Bacteria UP000006034 491169497, 316922874 EFV44098.1 WP_005027866.1 419 427 no 1888634 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 997346 Desmospora sp. 8437 Bacteria UP000004046 497397060, 332969750 EGK08762.1 WP_009711273.1 575 575 yes 1888635 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 1339269, 1339314 Bacteroides fragilis, Bacteroides fragilis str. Korea 419, Bacteroides fragilis str. 3976T8 Bacteria UP000036847, UP000021843, UP000020938 695554478, 596137432, 596110712 EXZ94165.1, EXZ73023.1 WP_032598392.1 564 564 yes 1888636 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 70993 Flexithrix dorotheae Bacteria 522016418 WP_020527689.1 621 622 yes 1888637 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144669 Acinetobacter sp. CIP 102637 Bacteria UP000023788 490938494, 479960154 ENV05113.1 WP_004800331.1 fig|1144669.3.peg.2625 626 631 yes 1888638 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1127743 Bacillus sp. 5B6 Bacteria UP000005799 494884155, 385148481 EIF12418.1 WP_007610204.1 fig|1127743.3.peg.693 589 589 yes 1888639 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262769 Clostridium sp. CAG:1013 Environmental samples UP000018382 512135810, 511346717 WP_016404778.1 241 258 no 1888640 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1234595 alpha proteobacterium JLT2015 Bacteria UP000011717 495877217, 451960660 EMD83072.1 WP_008601796.1 615 622 yes 1888641 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553239 Vibrio breoganii Bacteria 515595306 WP_017027927.1 640 643 yes 1888642 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1310611 Acinetobacter baumannii 466760 Bacteria UP000022459 587901192 EXB89474.1 481 487 no 1888643 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 559 559 yes 1888644 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 88724, 1227496 Natrinema versiforme, Natrinema versiforme JCM 10478 Archaea 493474404, 445617467 ELY71065.1 WP_006429412.1 L9YAJ8 L9YAJ8_9EURY 458 481 yes 1888645 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 556260 Bacteroides dorei 5_1_36/D4 Bacteria UP000004818 229436307 EEO46384.1 565 565 yes 1888646 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1157679 Oxalobacteraceae bacterium JGI 0001004-K23 Bacteria 516711671 WP_018058147.1 635 637 yes 1888647 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 321662, 1395516 Pseudomonas moraviensis, Pseudomonas moraviensis R28 Bacteria UP000024771 566142524, 565417710 ETF10222.1 WP_024011341.1 628 629 yes 1888648 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1310680, 1310639, 1217674, 575589, 596318 Acinetobacter baumannii 1239920, Acinetobacter baumannii 272263, Acinetobacter radioresistens NIPH 2130, Acinetobacter radioresistens SH164, Acinetobacter radioresistens SK82 Bacteria UP000023798, UP000023779, UP000018427, UP000018453, UP000018419 491158725, 588182831, 587897924, 480046957, 262298134, 255301933 EXE56568.1, EXB86385.1, ENV86129.1, EEY86048.1, EET81177.1 WP_005017112.1 fig|596318.3.peg.2741, fig|1217674.3.peg.1408, fig|575589.3.peg.1887 626 630 yes 1888649 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1125723 Porphyromonas sp. oral taxon 279 str. F0450 Bacteria UP000004156 402266750 EJU16167.1 fig|1125723.3.peg.1391 597 603 yes 1888650 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 13333 Amborella trichopoda Plants UP000017836 586644322, 548831639 ERM94447.1 XP_006827210.1 551 642 yes 1888651 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702, 698957 Gardnerella vaginalis, Gardnerella vaginalis 1500E Bacteria UP000037770, UP000032875 490228899, 388060908 EIK83583.1 WP_004127246.1 fig|698957.3.peg.325 609 886 yes 1888652 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 85643 Thauera sp. MZ1T Bacteria UP000002186 501581637, 237625368 ACR02058.1 WP_012585957.1 fig|85643.4.peg.3380 639 639 yes 1888653 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33811 518868605 WP_020024495.1 621 622 yes 1888654 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 230105, 1026882 Methylophaga aminisulfidivorans, Methylophaga aminisulfidivorans MP Bacteria UP000003544 494244245, 333789107 EGL54989.1 WP_007144875.1 602 603 yes 1888655 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1182704 Escherichia coli, Escherichia coli KTE108 Bacteria UP000036210, UP000014187 510926040, 508457205 EOW26916.1 WP_016246773.1 fig|1182704.3.peg.1302 626 631 yes 1888656 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 338 516522148 WP_017910514.1 622 625 yes 1888657 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116023 Escherichia coli, Escherichia coli 2861200 Bacteria UP000036210, UP000012286 490085768, 476160574 EMV82051.1 WP_003987736.1 fig|1116023.3.peg.4784 626 631 yes 1888658 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 85874, 1089553 Thermacetogenium phaeum, Thermacetogenium phaeum DSM 12270 Bacteria UP000053326, UP000000467 504864188, 409106293 AFV12418.1 WP_015051290.1 422 432 yes 1888659 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 85874, 1089553 Thermacetogenium phaeum, Thermacetogenium phaeum DSM 12270 Bacteria UP000053326, UP000000467 504864187, 409106292 AFV12417.1 WP_015051289.1 419 426 yes 1888660 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 574560, 1004151 Photorhabdus temperata, Photorhabdus temperata subsp. khanii NC19 Bacteria UP000018957 738961882, 572733201 ETS31385.1 WP_036845769.1 620 642 yes 1888661 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40545, 1203554 Sutterella wadsworthensis, Sutterella wadsworthensis HGA0223 Bacteria UP000014400 512680332, 512179113 EPD99818.1 WP_016473983.1 fig|1203554.3.peg.609 480 564 yes 1888662 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 131081 Corynebacterium capitovis Bacteria 516648194 WP_018017183.1 576 576 yes 1888663 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1002809 Solibacillus silvestris StLB046 Bacteria UP000006691 327438957 fig|1002809.3.peg.906 595 596 yes 1888664 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 816, 817, 1073386, 1263047 Bacteroides fragilis, Bacteroides fragilis HMW 610, Bacteroides fragilis CAG:558 Bacteria, Environmental samples UP000036847, UP000005807, UP000018103 492315384, 680466189, 663466535, 404587329, 524167642 KFX74984.1, KER61371.1, EKA91879.1 WP_005806421.1 fig|1073386.3.peg.742 564 564 yes 1888665 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28108, 1300259, 1300258, 1004786 Alteromonas macleodii, Alteromonas macleodii str. 'Ionian Sea UM4b', Alteromonas macleodii str. 'Ionian Sea UM7', Alteromonas macleodii str. 'Adriatic Sea 1' Bacteria UP000031168, UP000014903, UP000014905, UP000000222 504878807, 521348826, 521343915, 410817048 AGQ00010.1, AGP95679.1, AFV83665.1 WP_015065909.1 fig|1004786.3.peg.141 636 642 yes 1888666 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 480, 857576, 857579 Moraxella catarrhalis, Moraxella catarrhalis B496, Moraxella catarrhalis 103P14B1 Bacteria UP000058148, UP000023778, UP000023790 489758252, 326569023, 326562305 EGE19092.1, EGE12631.1 WP_003662209.1 fig|857576.3.peg.666, fig|857579.3.peg.1624 618 623 yes 1888667 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29466, 768727, 479436 Veillonella parvula, Veillonella parvula ACS-068-V-Sch12, Veillonella parvula DSM 2008 Bacteria UP000054707, UP000003372, UP000007968 490836275, 333975954, 269094147 EGL76828.1, ACZ24138.1 WP_004698352.1 fig|479436.4.peg.998, fig|768727.3.peg.1561 434 434 yes 1888668 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 687914 Salmonella enterica, Salmonella enterica subsp. enterica serovar Rissen str. 150 Bacteria UP000054489, UP000030118 553859238, 444806187 ELX33923.1 WP_023138018.1 622 627 yes 1888669 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1227350 Paenibacillus sp. FSL H8-237 Bacteria UP000019045 738790135, 573562571 ETT61221.1 WP_036681367.1 580 580 yes 1888670 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1144672 Acinetobacter sp. CIP 56.2 Bacteria UP000013209 490940353, 479966188 ENV10742.1 WP_004802185.1 fig|1144672.3.peg.495 626 631 yes 1888671 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 436 462 yes 1888672 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550 Enterobacter cloacae Bacteria UP000036177 515953495, 771189847 KJN38830.1 WP_017384078.1 626 631 yes 1888673 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 317, 629264 Pseudomonas syringae, Pseudomonas syringae Cit 7 Bacteria UP000028642, UP000005924 489461049, 330951444 EGH51704.1 WP_003366257.1 521 523 no 1888674 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 1384061, 1211579 Pseudomonas putida S13.1.2, Pseudomonas putida NBRC 14164 Bacteria UP000033260, UP000016702 512745238, 764076807, 512385992 AJQ50239.1 WP_016501909.1 fig|1211579.3.peg.4990, fig|1217722.3.peg.2774 625 626 yes 1888675 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1452, 1239783 Bacillus atrophaeus, Bacillus atrophaeus UCMB-5137 Bacteria UP000031779, UP000014005 498486336, 830323837 AKL83611.1 WP_010788024.1 fig|1239783.3.peg.841 590 590 yes 1888676 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1172192, 1328313 Catenovulum agarivorans, Catenovulum agarivorans DS-2 Bacteria UP000019276 737019658, 584424756 EWH09518.1 WP_035015159.1 640 641 yes 1888677 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 1045856 Enterobacter cloacae, Enterobacter cloacae EcWSU1 Bacteria UP000036177, UP000007838 503934170, 365747434 AEW71661.1 WP_014168164.1 fig|1045856.3.peg.210 626 631 yes 1888678 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116022 Escherichia coli, Escherichia coli 2860650 Bacteria UP000036210, UP000012199 485776078, 476787025 ENA88763.1 WP_001399559.1 fig|1116022.3.peg.4712 626 631 yes 1888679 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 72556, 742159 Achromobacter piechaudii, Achromobacter piechaudii ATCC 43553 Bacteria UP000036804, UP000004510 493247480, 292819084 EFF78119.1 WP_006216235.1 636 637 yes 1888680 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262891 Eubacterium sp. CAG:603 Environmental samples UP000018312 547247923, 524128041 WP_021983611.1 437 437 yes 1888681 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 129337, 1136178, 581103 Geobacillus thermoglucosidans TNO-09.020, Geobacillus sp. Y4.1MC1 Bacteria UP000005818, UP000002034 489345924, 383365657, 311217464 EID42950.1, ADP76068.1 WP_003253060.1 fig|581103.3.peg.1354, fig|1136178.3.peg.3236 573 573 yes 1888682 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59893 Paenibacillus peoriae Bacteria UP000059259 498034296 WP_010348452.1 594 595 yes 1888683 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 105559 Nitrosococcus watsoni C-113 Bacteria UP000000393 299538913 ADJ27230.1 fig|105559.4.peg.284 622 624 yes 1888684 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1235790 Eubacterium sp. 14-2 Bacteria UP000014176 510874959, 508147885 EOT24700.1 WP_016215938.1 fig|1235790.3.peg.3147 433 434 yes 1888685 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33047, 1094502 Bartonella vinsonii, Bartonella vinsonii subsp. berkhoffii str. Tweed Bacteria UP000014011 498391073, 478421233 ENN94893.1 WP_010704983.1 fig|1094502.3.peg.683 602 611 yes 1888686 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81464 Anaeromusa acidaminophila Bacteria 517533079 WP_018703287.1 430 433 yes 1888687 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 984237 Salmonella enterica subsp. enterica serovar Mbandaka str. ATCC 51958 Bacteria UP000017348 554203285 ESG41621.1 404 406 yes 1888688 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 984237 Salmonella enterica subsp. enterica serovar Mbandaka str. ATCC 51958 Bacteria UP000017348 554203286 ESG41622.1 182 225 no 1888689 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 1073388, 457424 Bacteroides fragilis, Bacteroides fragilis HMW 616, Bacteroides fragilis 3_1_12 Bacteria UP000036847, UP000006086, UP000005101 492215595, 404577409, 313136023 EKA82147.1, EFR53383.1 WP_005778057.1 fig|1073388.3.peg.1973, fig|457424.5.peg.1496 564 564 yes 1888690 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 698951 Gardnerella vaginalis 75712 Bacteria UP000003525 388052188 EIK75212.1 fig|698951.3.peg.992 609 881 yes 1888691 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 507, 511, 1386079, 1069631 Alcaligenes faecalis, Alcaligenes sp. EGD-AK7, Alcaligenes sp. HPC1271 Bacteria UP000068452, UP000016497, UP000011876 497075913, 700680292, 551191704, 422886794 KGP02296.1, ERT55024.1, EKU29206.1 WP_009460552.1 fig|1069631.3.peg.2922 637 638 yes 1888692 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173, 1049904, 1001590, 1193017, 1193018 Leptospira interrogans, Leptospira interrogans serovar Grippotyphosa str. UI 12764, Leptospira interrogans str. 2006001854, Leptospira interrogans serovar Grippotyphosa str. 2006006986, Leptospira interrogans serovar Grippotyphosa str. Andaman Bacteria UP000037872, UP000012165, UP000012128, UP000002833, UP000006325 488005280, 464283163, 464149031, 410434405, 410022316 EMN80442.1, EMM81538.1, EKP83543.1, EKO89093.1 WP_002076952.1 fig|1193018.3.peg.937, fig|996810.3.peg.1611, fig|1193017.3.peg.4954, fig|1049904.3.peg.3175 441 495 yes 1888693 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1124961 Salmonella enterica, Salmonella enterica subsp. enterica serovar Panama str. ATCC 7378 Bacteria UP000054489, UP000017327 555219319, 554171779 ESG11204.1 WP_023212142.1 626 631 yes 1888694 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 909613 Actinokineospora sp. EG49 Bacteria UP000019277 737301948, 583001056 EWC60610.1 WP_035284932.1 545 553 yes 1888695 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 520, 1331268 Bordetella pertussis, Bordetella pertussis Bp H973 Bacteria UP000061651, UP000018693 566085159, 565744152 ETH52757.1 WP_023998551.1 656 658 no 1888696 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43, 1242864 Cystobacter fuscus, Cystobacter fuscus DSM 2262 Bacteria UP000011682 488702292, 528057240 EPX62028.1 WP_002626277.1 623 626 yes 1888697 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 496 609 yes 1888698 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1402559 Pseudomonas aeruginosa, Pseudomonas aeruginosa BL18 Bacteria UP000065817, UP000017522 553765870, 552246470 ERV06976.1 WP_023098176.1 627 627 yes 1888699 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 466 499 yes 1888700 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384, 754522 Rhizobium leguminosarum, Rhizobium leguminosarum bv. trifolii WSM2012 Bacteria UP000005112 489667413, 393171734 EJC71779.1 WP_003571693.1 603 608 yes 1888701 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263050 Bacteroides ovatus CAG:22 Environmental samples UP000018233 547788560, 524408890 WP_022199085.1 565 565 yes 1888702 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 522773, 1331060 Sphingobium sp. DS20, Sphingobium lactosutens DS20 Bacteria UP000015531 544809743, 530271873 EQB14202.1 WP_021226607.1 623 631 yes 1888703 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1126, 1160283, 1160281, 1160286 Microcystis aeruginosa, Microcystis aeruginosa PCC 9807, Microcystis aeruginosa PCC 9443, Microcystis aeruginosa PCC 9717 Bacteria UP000003613, UP000003480, UP000003172 488844768, 389804694, 389730956, 389716685 WP_002757174.1 fig|1160281.3.peg.4887, fig|1160286.3.peg.4027, fig|1160283.3.peg.667 457 460 yes 1888704 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 371601, 997892 Bacteroides xylanisolvens, Bacteroides xylanisolvens CL03T12C04 Bacteria UP000003566 495297908, 392693470 EIY86702.1 WP_008022660.1 fig|997892.3.peg.1927 565 565 yes 1888705 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 439386 Sulfolobus islandicus Y.G.57.14 Archaea UP000002308 228009229 ACP44991.1 C3NBK6 C3NBK6_SULIY 160 161 no 1888706 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56458 Xanthomonas sacchari Bacteria UP000031138 498029227 WP_010343383.1 622 625 yes 1888707 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570, 244366, 1182695 Klebsiella variicola, Klebsiella sp. KTE92 Bacteria UP000037523, UP000014001 507089378, 749148870, 742126907, 500616507, 758075042 AJE90694.1, AJA95042.1, EOQ57013.1 WP_016160091.1 fig|1182695.3.peg.100 626 631 yes 1888708 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 420994, 1346791 Sphingobium ummariense, Sphingobium ummariense RL-3 Bacteria UP000015523 544908935, 530440427 EQB30956.1 WP_021319006.1 623 631 yes 1888709 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 258, 525373 Sphingobacterium spiritivorum, Sphingobacterium spiritivorum ATCC 33861 Bacteria UP000006258 489084267, 300759145 EFK55972.1 WP_002994178.1 605 605 yes 1888710 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3218 Physcomitrella patens Plants UP000006727 UP000006727 168028666, 162681827 EDQ68250.1 XP_001766848.1 559 668 yes 1888711 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 765914 Thiorhodospira sibirica ATCC 700588 Bacteria UP000003058 349791546 EGZ45427.1 fig|765914.3.peg.1772 601 607 yes 1888712 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 163003 Thermococcus sp. CL1 Archaea UP000006064 504600792, 390518521 AFL94253.1 WP_014787894.1 I3ZRB9 I3ZRB9_9EURY 426 426 yes 1888713 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 338191, 1229909 Candidatus Nitrosopumilus sp. AR2 Archaea UP000006100 504777628, 407047606 AFS82358.1 WP_014964730.1 K0B8A6 K0B8A6_9ARCH 442 442 yes 1888714 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 88688, 509190 Caulobacter segnis, Caulobacter segnis ATCC 21756 Bacteria UP000002629 502843583, 295430720 ADG09892.1 WP_013078559.1 fig|509190.6.peg.1435 612 612 3EPO, 3EPN, 4S2A yes 1888715 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 471223 Geobacillus sp. WCH70 Bacteria UP000002386 502275142, 239806232, 259517486 ACS23297.1 WP_012749111.1 C5D571 THIC_GEOSW Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7388734 fig|471223.3.peg.405 573 573 yes 1888716 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 77554579 ABA97375.1 B8YEK4 OGR1_ORYSJ Pentatricopeptide repeat-containing protein OGR1, mitochondrial {ECO:0000305} 140 794 no 1888717 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053193 Bacillus cereus, Bacillus cereus BAG6O-2 Bacteria UP000036076, UP000002926 488041525, 402432120 EJV64180.1 WP_002112922.1 fig|1053193.3.peg.2737 586 586 yes 1888718 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 79923 Clonorchis sinensis Invertebrates UP000008909 358256874 436 436 no 1888719 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 613199 Prochlorococcus sp. W8 Bacteria 518307978 WP_019478185.1 439 441 yes 1888720 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287182 Mesorhizobium sp. L48C026A00 Bacteria UP000019863 563191347 ESZ14412.1 521 533 yes 1888721 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 223903 Hymenobacter norwichensis Bacteria 551196624 WP_022824699.1 624 624 yes 1888722 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 913327 gamma proteobacterium SCGC AAA007-O20 Bacteria 498191753 WP_010505909.1 616 616 yes 1888723 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262736 Bacteroides sp. CAG:144 Environmental samples UP000018228 547462970, 524257206 WP_022082145.1 171 171 no 1888724 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305, 859655 Ralstonia solanacearum, Ralstonia solanacearum CMR15 Bacteria UP000029286, UP000013571 523414688, 299068320 WP_020750010.1 629 631 yes 1888725 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|1218173.3.peg.3248 580 580 yes 1888726 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 658655, 1263106 Lachnospiraceae bacterium 1_4_56FAA, Ruminococcus gnavus CAG:126 Bacteria, Environmental samples UP000004289, UP000018114 496566335, 336008252, 524199259 EGN38271.1 WP_009267455.1 fig|658655.3.peg.1531 433 434 yes 1888727 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992145 Yersinia pestis, Yersinia pestis PY-29 Bacteria UP000000815 UP000031825, UP000003008 488339111, 391517416 EIR70227.1 WP_002408496.1 179 209 no 1888728 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39773, 686340 Methylomicrobium album BG8 Bacteria UP000005090 491511162, 380882218 EIC28095.1 WP_005368796.1 621 622 yes 1888729 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 436, 714995, 1231352 Gluconacetobacter hansenii, Gluconacetobacter hansenii ATCC 23769, Komagataeibacter hansenii JCM 7643 Bacteria UP000006468, UP000032681 489713020, 295978828, 775280352 EFG85553.1 WP_003617157.1 605 613 yes 1888730 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1150157 Bacillus sp. FJAT-13831 Bacteria 515720853 WP_017153453.1 586 586 yes 1888731 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1172194 Hydrocarboniphaga effusa AP103 Bacteria UP000003704 391859316 EIT69845.1 fig|1172194.4.peg.3326 626 633 yes 1888732 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1164990, 1165094 Richelia intracellularis, Richelia intracellularis HH01 Bacteria UP000019767, UP000053051 495511207, 471329361 WP_008235852.1 fig|1165094.3.peg.2199 458 459 yes 1888733 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1050222 Paenibacillus sp. Aloe-11 Bacteria UP000005078 494670837, 375081058 EHS59274.1 WP_007428778.1 594 595 yes 1888734 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 654421 Anoxybacillus sp. SK3-4 Bacteria UP000015522 544662686, 528962155 EPZ37142.1 WP_021096096.1 563 567 yes 1888735 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1354303 Psychrobacter aquaticus CMS 56 Bacteria UP000016761 545674379 ERL55724.1 669 709 yes 1888736 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310800, 1310623 Acinetobacter baumannii, Acinetobacter baumannii 1000160, Acinetobacter baumannii 146457 Bacteria UP000028632, UP000021741, UP000023317 696295602, 602185165, 587855356 EYT14356.1, EXB45359.1 WP_032871207.1 626 631 yes 1888737 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1089453 Gordonia sputi NBRC 100414 Bacteria UP000005845 377527443 fig|1089453.3.peg.2720 550 566 yes 1888738 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78331, 1205674, 1205676, 1048245 Mycobacterium canettii, Mycobacterium canettii CIPT 140070010, Mycobacterium canettii CIPT 140060008, Mycobacterium canettii CIPT 140010059 Bacteria UP000010804, UP000010806, UP000008896 503766145, 432161100, 432153120, 340003638 WP_014000221.1 fig|1205676.3.peg.468, fig|1205674.3.peg.911, fig|78331.5.peg.457, fig|1246119.3.peg.459 544 547 yes 1888739 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626934, 742818 Slackia piriformis, Slackia piriformis YIT 12062 Bacteria UP000006069 496429422, 404389351 EJZ84427.1 WP_009138269.1 fig|742818.3.peg.27 432 433 yes 1888740 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65058, 945712 Corynebacterium ulcerans, Corynebacterium ulcerans BR-AD22 Bacteria UP000029905, UP000008887 503677707, 334699341 AEG84137.1 WP_013911783.1 fig|945712.3.peg.1476 558 569 yes 1888741 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1522, 999413, 457422 Clostridium innocuum, Clostridium innocuum 2959, Erysipelotrichaceae bacterium 2_2_44A Bacteria UP000030008, UP000013051, UP000003043 488678770, 480643030, 345903276 ENY87462.1, EGX73041.1 WP_002607543.1 fig|457422.3.peg.3396, fig|999413.4.peg.1961 435 435 yes 1888742 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263025 Firmicutes bacterium CAG:466 Environmental samples UP000018338 547847331, 524485003 WP_022254544.1 433 434 yes 1888743 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263095 Paraprevotella clara CAG:116 Environmental samples UP000017958 547244765, 524125317 WP_021980542.1 574 575 yes 1888744 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 32022, 889238, 889236 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni, Campylobacter jejuni subsp. jejuni LMG 23211, Campylobacter jejuni subsp. jejuni LMG 9872 Bacteria UP000065538, UP000032540, UP000003144, UP000003911 489022589, 765207705, 764100698, 764097598, 764096808, 380675835, 380671944, 685822901 KJD98764.1, KJD29820.1, KJD26801.1, KJD26034.1, EIB90726.1, EIB87135.1 WP_002933069.1 fig|889238.3.peg.1180, fig|889236.3.peg.662 430 430 yes 1888745 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 212663 Vibrio tasmaniensis Bacteria 515668648 WP_017101248.1 640 649 yes 1888746 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1155714 Streptomyces sp. LaPpAH-108 Bacteria 517372873 WP_018547574.1 594 598 yes 1888747 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2736 Verrucomicrobium spinosum Bacteria 497647622 WP_009961806.1 669 669 yes 1888748 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 39669, 679901 Methanosalsum zhilinae, Methanosalsum zhilinae DSM 4017 Archaea UP000006622 503663310, 336476025, 335929406 AEH59947.1 WP_013897386.1, YP_004615166.1 F7XMT0 F7XMT0_METZD 406 415 no 1888749 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 875171, 1208323 Celeribacter sp. L-6, Celeribacter baekdonensis B30 Bacteria UP000006762 497258358, 407200387 EKE70395.1 WP_009572575.1 fig|1208323.3.peg.2702 591 599 yes 1888750 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1496, 1151428 Clostridium difficile, Clostridium difficile P59 Bacteria UP000058232, UP000015700 545052593, 531729819 EQK06578.1 WP_021426331.1 433 433 yes 1888751 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454726 Candidatus Caldatribacteirum californiense Bacteria 516501998 WP_017890438.1 430 431 yes 1888752 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43305, 515622 Clostridium proteoclasticum, Butyrivibrio proteoclasticus B316 Bacteria UP000001299 503045452, 302394867 ADL33772.1 WP_013280428.1 fig|515622.3.peg.1040 434 434 yes 1888753 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 518679671 WP_019841364.1 626 631 yes 1888754 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 136843, 1282356, 1205750 Pseudomonas poae RE*1-1-14, Pseudomonas fluorescens BRIP34879 Bacteria UP000011817, UP000011215 489329011, 445203511, 440377858 AGE28720.1, ELQ14493.1 WP_003236291.1 fig|1282356.3.peg.4624, fig|1205750.3.peg.3527 629 634 yes 1888755 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 497679492 WP_009993676.1 330 331 yes 1888756 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 770, 1412841, 1412840, 234826 Anaplasma marginale, Anaplasma marginale str. Dawn, Anaplasma marginale str. Gypsy Plains, Anaplasma marginale str. St. Maries Bacteria UP000017757, UP000017743, UP000006557 499426810, 556856866, 556855732, 56387901 AGZ79580.1, AGZ78745.1, AAV86488.1 WP_011114274.1 Q5PB42 THIC_ANAMM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 820736, 5499761, 10348413 fig|234826.3.peg.444 560 600 yes 1888757 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630, 1262463, 1262464 Yersinia enterocolitica, Yersinia enterocolitica (type O:9) str. YE212/02, Yersinia enterocolitica (type O:9) str. YE56/03 Bacteria UP000029427, UP000018236, UP000018394 519715036, 510489056, 486104394 WP_020282430.1 617 628 yes 1888758 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 359408, 583345 Methylotenera mobilis, Methylotenera mobilis JLW8 Bacteria UP000002742 502390355, 253982088 ACT46946.1 WP_012777403.1 fig|583345.3.peg.34 624 627 yes 1888759 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 567106 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni IA3902 Bacteria UP000065538, UP000001516 504329600, 284925720 ADC28072.1 WP_014516702.1 fig|567106.3.peg.447 430 430 yes 1888760 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 186802, 457412, 1262967 Ruminococcus sp. 5_1_39BFAA, Ruminococcus sp. CAG:9 Bacteria, Environmental samples UP000004663, UP000018027 495982490, 251848232, 524859708 EES76197.1 WP_008707069.1 fig|457412.4.peg.2680 435 436 yes 1888761 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1773, 1267357, 1422062, 1422061, 1422040, 1422037, 1422039, 1422038, 1422030, 1422027, 1422026, 1422023, 1422022, 1422019, 1422018, 1421999, 1421994, 1397936, 1397935, 1397934, 1397929, 1397925, 1397924, 1397916, 1397888, 1421993, 1324274, 1324271, 1324267, 1324252, 1295790, 1295782, 1421982, 1421978, 1421977, 1421941, 1448559, 1448530, 1448528, 1448520, 1448506, 1448493, 1448495, 1448488 Mycobacterium tuberculosis, Mycobacterium tuberculosis TKK-01-0020, Mycobacterium tuberculosis TB_RSA146, Mycobacterium tuberculosis TB_RSA145, Mycobacterium tuberculosis TB_RSA124, Mycobacterium tuberculosis TB_RSA121, Mycobacterium tuberculosis TB_RSA123, Mycobacterium tuberculosis TB_RSA122, Mycobacterium tuberculosis TB_RSA114, Mycobacterium tuberculosis TB_RSA111, Mycobacterium tuberculosis TB_RSA110, Mycobacterium tuberculosis TB_RSA107, Mycobacterium tuberculosis TB_RSA106, Mycobacterium tuberculosis TB_RSA103, Mycobacterium tuberculosis TB_RSA102, Mycobacterium tuberculosis TB_RSA83, Mycobacterium tuberculosis TB_RSA78, Mycobacterium tuberculosis TKK_04_0042, Mycobacterium tuberculosis TKK_04_0046, Mycobacterium tuberculosis TKK_04_0045, Mycobacterium tuberculosis TKK_04_0036, Mycobacterium tuberculosis TKK_04_0008, Mycobacterium tuberculosis TKK_04_0007, Mycobacterium tuberculosis TKK_04_0021, Mycobacterium tuberculosis TKK_02_0067, Mycobacterium tuberculosis TB_RSA77, Mycobacterium tuberculosis TKK-01-0064, Mycobacterium tuberculosis TKK-01-0061, Mycobacterium tuberculosis TKK-01-0057, Mycobacterium tuberculosis TKK-01-0042, Mycobacterium tuberculosis TBR74, Mycobacterium tuberculosis TBR66, Mycobacterium tuberculosis TB_RSA66, Mycobacterium tuberculosis TB_RSA62, Mycobacterium tuberculosis TB_RSA61, Mycobacterium tuberculosis TB_RSA25, Mycobacterium tuberculosis TKK_04_0074, Mycobacterium tuberculosis TKK_05SA_0016, Mycobacterium tuberculosis TKK_05SA_0012, Mycobacterium tuberculosis TKK_05MA_0056, Mycobacterium tuberculosis TKK_05MA_0035, Mycobacterium tuberculosis TKK_05MA_0012, Mycobacterium tuberculosis TKK_05MA_0016, Mycobacterium tuberculosis TKK_05MA_0004 Bacteria UP000065426, UP000028409, UP000025541, UP000026408, UP000026831, UP000026116, UP000026359, UP000026402, UP000026146, UP000026338, UP000026421, UP000026431, UP000025959, UP000025496, UP000025396, UP000025310, UP000026234, UP000026017, UP000026698, UP000026321, UP000025909, UP000025639, UP000025389, UP000025571, UP000025798, UP000026188, UP000026212, UP000025637, UP000026094, UP000026144, UP000027579, UP000027540, UP000025300, UP000025692, UP000026672, UP000025440, UP000026420, UP000026588, UP000025928, UP000026676, UP000025561, UP000025324, UP000026577, UP000025325 685987971, 654050612, 626324796, 626320687, 626240710, 626230635, 626227322, 626225549, 626200250, 626196708, 626192487, 626178057, 626172717, 626166901, 626157671, 626077255, 626060532, 625758928, 625754018, 625750016, 625730958, 625709861, 625706898, 625680087, 625567895, 625388887, 625067278, 625045733, 625039995, 624978754, 624774113, 624772744, 624026181, 624020362, 624010234, 623868643, 622040386, 621954006, 621945059, 621920489, 621888310, 621856946, 621855979, 621842993 KEC49677.1, KCK62480.1, KCK58497.1, KCJ80008.1, KCJ70147.1, KCJ66904.1, KCJ65186.1, KCJ40416.1, KCJ36994.1, KCJ32881.1, KCJ19443.1, KCJ14198.1, KCJ08479.1, KCI99461.1, KCI20665.1, KCI04223.1, KCF10013.1, KCF05177.1, KCF01242.1, KCE82432.1, KCE61613.1, KCE58703.1, KCE32279.1, KCD22048.1, KCB56507.1, KCA18545.1, KBZ97209.1, KBZ91503.1, KBZ30800.1, KBX27669.1, KBX26305.1, KBP88320.1, KBP82549.1, KBP72462.1, KBO31912.1, KAW28363.1, KAV43605.1, KAV34831.1, KAV10617.1, KAU79041.1, KAU48277.1, KAU47319.1, KAU34594.1 WP_031694251.1 544 547 yes 1888762 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 546, 742730 Citrobacter freundii, Citrobacter freundii 4_7_47CFAA Bacteria UP000030582, UP000004945 489923550, 363646547 EHL85789.1 WP_003826896.1 fig|742730.3.peg.788 626 632 yes 1888763 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47877 Pseudomonas amygdali Bacteria UP000050412 497897840 WP_010211996.1 627 629 yes 1888764 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 1350471, 1263059 Bifidobacterium longum, Bifidobacterium longum subsp. longum 1-5B, Bifidobacterium longum CAG:69 Bacteria, Environmental samples UP000028505, UP000028195, UP000018324 547239406, 665771468, 524120636 KEY21359.1 WP_021975446.1 635 917 yes 1888765 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392998 Candidatus Methanoperedens nitroreducens Archaea 851165864, 630828614 KCZ70331.1 WP_048094073.1 A0A062UTF9 A0A062UTF9_9EURY 419 426 yes 1888766 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1414851 Pelistega sp. HM-7 Bacteria UP000018766 565871005, 564865736 ETD67948.1 WP_023952551.1 621 623 yes 1888767 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1119528 Methyloversatilis sp. FAM1 Bacteria 518758340 WP_019915859.1 637 641 yes 1888768 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 706587 Desulfomonile tiedjei DSM 6799 Bacteria UP000006055 390626937, 390625827 AFM28144.1, AFM27034.1 fig|706587.4.peg.4996 430 457 yes 1888769 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626 635 yes 1888770 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 665946 Neisseria sp. GT4A_CT1 Bacteria UP000005946 496669369, 348611093 EGY60763.1 WP_009311859.1 fig|665946.3.peg.1286 625 633 yes 1888771 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 886293 Singulisphaera acidiphila DSM 18658 Bacteria UP000010798 430019042 AGA30756.1 466 478 yes 1888772 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 523742, 1288826 Marinobacter santoriniensis, Marinobacter santoriniensis NKSG1 Bacteria UP000011960 496226712, 469610878 EMP54027.1 WP_008940747.1 fig|1288826.3.peg.3609 622 625 yes 1888773 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1215343 Liberibacter crescens BT-1 Bacteria UP000010799 430799462 AGA64133.1 fig|1215343.11.peg.147 601 605 yes 1888774 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 255616, 662480 Haloferax sulfurifontis, Haloferax sulfurifontis ATCC BAA-897 Archaea 494486458, 445737848 ELZ89378.1 WP_007275931.1 M0I047 M0I047_9EURY 434 465 yes 1888775 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 671229, 944564 Veillonella sp. oral taxon 780, Veillonella sp. oral taxon 780 str. F0422 Bacteria UP000010295 496722603, 341597741 EGS40280.1 WP_009352752.1 434 434 yes 1888776 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 303, 1388760, 1331671 Pseudomonas putida, Pseudomonas putida SJ3, Pseudomonas putida H8234 Bacteria UP000054813, UP000017085, UP000014263 512731587, 551053653, 511523265 ERT19370.1, AGN80806.1 WP_016489471.1 fig|1331671.3.peg.5777 625 626 yes 1888777 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 133539, 472759 Nitrosococcus halophilus, Nitrosococcus halophilus Nc4 Bacteria UP000001844 502799367, 291582037 ADE16494.1 WP_013034343.1 fig|472759.3.peg.3637 623 625 yes 1888778 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 649746, 592015 Anaerobaculum hydrogeniformans, Anaerobaculum hydrogeniformans ATCC BAA-1850 Bacteria UP000005273 496493150, 289503294 EFD24458.1 WP_009201720.1 422 422 yes 1888779 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 213, 537971, 1206745, 1172562 Helicobacter cinaedi, Helicobacter cinaedi CCUG 18818, Helicobacter cinaedi ATCC BAA-847, Helicobacter cinaedi PAGU611 Bacteria UP000005755, UP000001956 489045247, 313128032, 396079645, 385147260 EFR45649.1 WP_002955472.1 fig|537971.5.peg.622, fig|1206745.3.peg.1870 458 459 yes 1888780 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644, 1448139 Aeromonas hydrophila, Aeromonas hydrophila YL17 Bacteria UP000032249, UP000019766 643373920, 604187413 AHV36856.1 WP_025202318.1 662 680 yes 1888781 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 59201, 1329901, 1347789, 595 Salmonella enterica, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Infantis str. 119944, Salmonella enterica subsp. enterica serovar Infantis str. 335-3, Salmonella enterica subsp. enterica serovar Infantis Bacteria UP000054489, UP000033855, UP000018750, UP000018713, UP000056952 566074389, 735839640, 735712785, 735699843, 735697065, 735696352, 564961676, 564956975, 733590167 KHQ08955.1, KHO83450.1, KHO70632.1, KHO67887.1, KHO67186.1, ETE48372.1, ETE43806.1 WP_023993917.1 626 631 yes 1888782 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 228748, 768672 Desulfurococcus fermentans, Desulfurococcus fermentans DSM 16532 Archaea UP000006175 504579911, 390937946, 390191053 AFL66109.1 WP_014767013.1, YP_006401684.1 I3XQ85 I3XQ85_9CREN 421 433 yes 1888783 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1268991, 1281185, 1182653, 1169362, 749529 Escherichia coli, Escherichia coli 908519, Escherichia coli UMEA 3117-1, Escherichia coli KTE46, Escherichia coli KTE45, Escherichia coli MS 57-2 Bacteria UP000036210, UP000017618, UP000016296, UP000010598, UP000010706, UP000003375 446039455, 553620972, 535532442, 431304303, 431279695, 324009486 ESD40644.1, EQW70771.1, ELF92833.1, ELF70646.1, EGB78705.1 WP_000117310.1 fig|1169362.3.peg.159, fig|749529.3.peg.720, fig|1182653.3.peg.4091 626 631 yes 1888784 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281125, 1181731, 1169368, 1144302 Escherichia coli, Escherichia coli HVH 198 (4-3206106), Escherichia coli KTE185, Escherichia coli KTE94, Escherichia coli SCI-07 Bacteria UP000036210, UP000016027, UP000014173, UP000010612, UP000006444 446039456, 535262720, 508552812, 431715992, 380345986 EQU06090.1, EOX20131.1, ELJ80134.1, EIA34291.1 WP_000117311.1 fig|1169368.3.peg.4443, fig|1181731.3.peg.4686, fig|1144302.3.peg.4053 626 631 yes 1888785 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1268998, 752784, 749531 Escherichia coli, Escherichia coli 908573, Escherichia coli KD2, Escherichia coli MS 69-1 Bacteria UP000036210, UP000017634, UP000005364, UP000004246 446039457, 553670234, 388389101, 300399271 ESD87476.1, EIL50639.1, EFJ82809.1 WP_000117312.1 fig|752784.3.peg.2445, fig|749531.3.peg.1077 626 631 yes 1888786 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358, 1315272, 1336745 Agrobacterium tumefaciens, Agrobacterium tumefaciens GW4, Agrobacterium radiobacter DSM 30147 Bacteria UP000064781, UP000027262, UP000019107 523695049, 648203430, 523372767 KDR86861.1, EPR07392.1 WP_020813455.1 600 607 yes 1888787 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168697 Salinispora arenicola Bacteria 517415830 WP_018587695.1 530 530 yes 1888788 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 118797 Lipotes vexillifer Mammals 602690114 XP_007457266.1 591 591 yes 1888789 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 561, 1169349, 1169351 Escherichia coli KTE31, Escherichia coli KTE33 Bacteria UP000014175, UP000013993 507089123, 508304697, 500610248 EOU77137.1, EOQ50932.1 WP_016159840.1 fig|1169351.3.peg.3466, fig|1169349.3.peg.4010 626 631 yes 1888790 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 300, 1390370 Pseudomonas mendocina, Pseudomonas mendocina EGD-AQ5 Bacteria UP000028008, UP000016524 545126397, 542007076 ERH52988.1 WP_021487851.1 627 627 yes 1888791 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444161 Escherichia coli, Escherichia coli 1-176-05_S3_C2 Bacteria UP000036210, UP000023206 447196856, 598673730 EYD81829.1 WP_001274112.1 626 631 yes 1888792 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 492670, 1385727 Bacillus methylotrophicus, Bacillus amyloliquefaciens subsp. plantarum NAU-B3 Bacteria UP000032090, UP000016891 549781119, 700308655, 549060726 AIU81018.1 WP_022552798.1 590 590 yes 1888793 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81031, 1280950 Hyphomonas johnsonii, Hyphomonas johnsonii MHS-2 Bacteria UP000025171 737646564, 630946029 KCZ92320.1 WP_035616548.1 648 657 yes 1888794 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168697 Salinispora arenicola Bacteria 517862764 WP_019032972.1 530 530 yes 1888795 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 466088 Acinetobacter sp. Ver3 Bacteria UP000023816 737280533, 612175765 EZQ12316.1 WP_035263924.1 627 631 yes 1888796 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 866790 Methanothermobacter thermautotrophicus CaT2 Archaea UP000031654 851312942, 427189962 WP_048176085.1 T2GKV4 T2GKV4_9EURY 424 424 yes 1888797 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408 Bacillus pumilus Bacteria UP000037521 736654296, 660485418, 635275450 KEO50294.1, KDE53198.1 WP_034661590.1 586 586 yes 1888798 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1403933 Veillonella sp. DORA_B_18_19_23 Bacteria UP000053161 566233906 ETI96273.1 145 145 no 1888799 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169153 Nocardiopsis sp. CNS639 Bacteria 518437861 WP_019608068.1 553 564 yes 1888800 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 58138, 485916 Desulfotomaculum acetoxidans, Desulfotomaculum acetoxidans DSM 771 Bacteria UP000002217 506237392, 257778562 ACV62456.1 WP_015757167.1 fig|485916.4.peg.1791 420 426 yes 1888801 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 58138, 485916 Desulfotomaculum acetoxidans, Desulfotomaculum acetoxidans DSM 771 Bacteria UP000002217 506237391, 257778561 ACV62455.1 WP_015757166.1 fig|485916.4.peg.1792 422 432 yes 1888802 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 288705 Renibacterium salmoninarum ATCC 33209 Bacteria UP000002007 162953301 ABY22816.1 fig|288705.3.peg.1105 393 438 no 1888803 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316 Pseudomonas stutzeri Bacteria UP000037382 643647302, 594029042 AHL77045.1 WP_025243255.1 626 626 yes 1888804 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 1619239, 1619245, 550, 888063 Enterobacter sp. 35027, Enterobacter sp. 35666, Enterobacter cloacae, Enterobacter hormaechei ATCC 49162 Bacteria UP000033427, UP000033659, UP000036177, UP000002984 493863788, 771261047, 771185608, 742984666, 333389671 KJN97206.1, KJN36614.1, AJB69300.1, EGK60831.1 WP_006810520.1 626 631 yes 1888805 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281183 Escherichia coli, Escherichia coli UMEA 3108-1 Bacteria UP000036210, UP000016388 545261504, 535518731 EQW57266.1 WP_021555362.1 626 631 yes 1888806 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 856, 469618 Fusobacterium varium, Fusobacterium varium ATCC 27725 Bacteria UP000004505 492749409, 251834929 EES63492.1 WP_005948561.1 fig|469618.3.peg.2790 425 425 yes 1888807 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1365186 Klebsiella pneumoniae KP-1 Bacteria UP000018459 542315201 ERI56362.1 584 586 yes 1888808 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1223566 Bradyrhizobium sp. CCGE-LA001 Bacteria UP000019052 404266230 EJZ31150.1 fig|1223566.3.peg.4473 623 632 yes 1888809 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 38323, 1402982, 1402981, 283166 Bartonella henselae, Bartonella henselae JK 51, Bartonella henselae JK 50, Bartonella henselae str. Houston-1 Bacteria UP000019802, UP000018919, UP000018925, UP000058422 499493782, 572287545, 572287034, 603661514, 81648085, 49238092 ETS10461.1, ETS09951.1 WP_011180422.1 Q6G477 THIC_BARHE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 600948 fig|283166.1.peg.455 601 610 yes 1888810 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 193462, 1352941 Streptomyces laceyi, Streptomyces niveus NCIMB 11891 Bacteria UP000017971 558885379, 558534692 EST26088.1 WP_023540301.1 594 596 yes 1888811 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 1201032 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni PT14 Bacteria UP000065538, UP000006307 504829328, 407905735 AFU42564.1 WP_015016430.1 fig|1201032.3.peg.439 430 430 yes 1888812 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82654 Pseudanabaena sp. PCC 7367 Bacteria UP000010386 504977960, 427989841 AFY70096.1 WP_015165062.1 fig|82654.3.peg.2120 460 463 yes 1888813 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 984, 485917 Pedobacter heparinus, Pedobacter heparinus DSM 2366 Bacteria UP000000852 506288507, 255345344 ACU04670.1 WP_015808282.1 fig|485917.5.peg.1413 627 627 yes 1888814 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1492, 1403941 Clostridium butyricum, Clostridium butyricum DORA_1 Bacteria UP000032253, UP000018876 567940304, 566223417 ETI88306.1 WP_024040890.1 433 433 yes 1888815 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 521011 Methanosphaerula palustris E1-9c Archaea UP000002457 219545340 ACL15790.1 B8GKA7 B8GKA7_METPE fig|521011.3.peg.437 414 432 no 1888816 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 586 586 yes 1888817 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4081 Solanum lycopersicum Plants UP000004994 UP000004994 460389516 XP_004240398.1 540 651 yes 1888818 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1073330, 700597 Streptomyces zinciresistens, Streptomyces sp. CCNWNQ0016 Bacteria UP000004217 494757065, 345639210 EGX60704.1 WP_007492473.1 fig|700597.3.peg.1211 591 594 yes 1888819 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35519, 1401079 Mogibacterium timidum, Mogibacterium timidum ATCC 33093 Bacteria UP000022645 738428015, 576985415 EUC58152.1 WP_036379407.1 436 437 yes 1888820 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 74109, 298386 Photobacterium profundum, Photobacterium profundum SS9 Bacteria UP000000593 499536140, 81615768, 46911747 WP_011216923.1 Q6LVY0 THIC_PHOPR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 771835 fig|298386.1.peg.2323 637 640 yes 1888821 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 913865 Desulfosporosinus sp. OT Bacteria UP000004928 344330681 EGW41968.1 fig|913865.3.peg.77 421 421 yes 1888822 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28108, 1300254 Alteromonas macleodii, Alteromonas macleodii str. 'Aegean Sea MED64' Bacteria UP000031168, UP000014907 566728649, 521326019 AGP80126.1 WP_024015466.1 636 642 yes 1888823 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1172181 Streptomyces sp. 303MFCol5.2 Bacteria 518974820 WP_020130695.1 600 608 yes 1888824 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1008, 984262 Saprospira grandis, Saprospira grandis str. Lewin Bacteria UP000007519 505729847, 378575184 AFC24185.1 WP_015691822.1 fig|984262.3.peg.1527 623 623 yes 1888825 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 186739, 1094564 Bartonella washoensis, Bartonella washoensis 085-0475 Bacteria UP000002646 493982635, 395419422 EJF85722.1 WP_006925523.1 fig|1094564.3.peg.832 602 611 yes 1888826 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 555791, 1229783 Staphylococcus massiliensis, Staphylococcus massiliensis S46 Bacteria UP000009885 496844358, 425481416 EKU48576.1 WP_009383142.1 fig|1229783.3.peg.1047, fig|1189613.3.peg.1114 581 581 yes 1888827 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 936565 Klebsiella sp. OBRC7 Bacteria UP000004118 497338561, 402282495 EJU31037.1 WP_009652774.1 fig|936565.3.peg.2158 626 631 yes 1888828 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 881, 883 Desulfovibrio vulgaris, Desulfovibrio vulgaris str. 'Miyazaki F' Bacteria UP000001361 501645330, 218756268 ACL07167.1 WP_012611361.1 fig|883.3.peg.218 419 429 no 1888829 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 17 Methylophilus methylotrophus Bacteria 517815177 WP_018985385.1 624 626 yes 1888830 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 189330, 742765, 1263073 Dorea formicigenerans 4_6_53AFAA, Dorea formicigenerans CAG:28 Bacteria, Environmental samples UP000004305, UP000018109 491478389, 345908282, 524521587 EGX77938.1 WP_005336130.1 fig|742765.5.peg.3, fig|411461.4.peg.1529 435 436 yes 1888831 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 457 465 yes 1888832 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 77133 uncultured bacterium Environmental samples UP000041370 575095503 433 433 yes 1888833 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262933 Prevotella sp. CAG:617 Environmental samples UP000018057 548321321, 524828655 WP_022510626.1 570 570 yes 1888834 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1033739 Kurthia sp. JC30 Bacteria 497975530 WP_010289686.1 594 594 yes 1888835 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1646532, 1217650, 1217651, 903945, 106648 Acinetobacter sp. Ag2, Acinetobacter bereziniae CIP 70.12, Acinetobacter bereziniae NIPH 3, Acinetobacter sp. WC-743, Acinetobacter berezinae Bacteria UP000034123, UP000013270, UP000011515, UP000042386 490963710, 819912763, 480051561, 479975995, 444766818, 748532721 KKW78898.1, ENV90662.1, ENV20038.1, ELW91077.1 WP_004825518.1 fig|1217651.3.peg.4029, fig|903945.3.peg.216, fig|981324.3.peg.768, fig|1217650.3.peg.3847 626 631 yes 1888836 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285540 Streptomyces thermolilacinus Bacteria 559790998 WP_023587729.1 590 592 yes 1888837 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37919, 1129896 Rhodococcus opacus, Rhodococcus opacus M213 Bacteria UP000028488, UP000005951 491406566, 414566406 EKT77241.1 WP_005264401.1 541 548 yes 1888838 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 663, 1231058 Vibrio alginolyticus, Vibrio alginolyticus E0666 Bacteria UP000066605, UP000011709 491539450, 451929998 EMD77721.1 WP_005397069.1 fig|1231058.3.peg.3902 640 646 yes 1888839 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626940, 1263101 Phascolarctobacterium sp. YIT 12068, Phascolarctobacterium succinatutens CAG:287 Bacteria UP000014937 545590818, 524589781 WP_021719476.1 433 433 yes 1888840 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1411, 1236973 Bacillus akibai, Bacillus akibai JCM 9157 Bacteria UP000018896 737694171, 568813951 WP_035663156.1 593 593 yes 1888841 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 617 yes 1888842 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116159 Escherichia coli, Escherichia coli P0302308.11 Bacteria UP000036210, UP000012256 485946749, 477013109 ENC98523.1 WP_001494604.1 fig|1116159.3.peg.4432 626 631 yes 1888843 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 658086 Lachnospiraceae bacterium 3_1_57FAA_CT1 Bacteria UP000003336 336010213 EGN40199.1 fig|658086.3.peg.3301 465 477 yes 1888844 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1085379, 1053234 Bacillus cereus, Bacillus cereus VDM006, Bacillus cereus VD136 Bacteria UP000036076, UP000013982, UP000013980 507040916, 500465884, 500450304 EOP77484.1, EOP63002.1 WP_016112575.1 fig|1053234.3.peg.303, fig|1085379.3.peg.213 586 586 yes 1888845 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 186802, 1609975, 742733 Clostridium sp. FS41, Clostridium citroniae WAL-17108 Bacteria UP000033604, UP000003763 495134140, 769365925, 354816209 KJJ76809.1, EHF00798.1 WP_007858949.1 fig|742733.3.peg.580 434 435 yes 1888846 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1772, 246196 Mycobacterium smegmatis, Mycobacterium smegmatis str. MC2 155 Bacteria UP000029911, UP000029906 504689782, 399229794 AFP37287.1 WP_014876884.1 535 545 yes 1888847 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 940, 608538 Hydrogenobacter thermophilus, Hydrogenobacter thermophilus TK-6 Bacteria UP000008982 502727865, 308751123, 288786919 ADO44606.1 WP_012962849.1 fig|608538.3.peg.200 451 455 yes 1888848 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29507, 1193049 Leptospira kirschneri, Leptospira kirschneri str. 2008720114 Bacteria UP000002851 490920374, 410357416 EKP04671.1 WP_004782245.1 fig|1193049.3.peg.2799 440 494 yes 1888849 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 303, 1399145 Pseudomonas putida, Pseudomonas putida S610 Bacteria UP000054813, UP000018085 558877366, 558525179 EST17118.1 WP_023532937.1 625 626 yes 1888850 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573064 Methanocaldococcus fervens AG86 Archaea UP000001495 256793299 ACV23968.1 C7P5Y6 C7P5Y6_METFA 428 428 yes 1888851 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 73913, 579137 Methanocaldococcus vulcanius, Methanocaldococcus vulcanius M7 Archaea UP000002063 506212944, 261369749 ACX72498.1 WP_015732719.1 C9RFZ6 C9RFZ6_METVM 426 426 yes 1888852 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53246, 43662 Pseudoalteromonas piscicida Bacteria UP000033599 498292927, 798741730 KJY91264.1 WP_010607083.1 645 650 yes 1888853 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 364410, 1051974 Granulibacter bethesdensis, Granulibacter bethesdensis CGDNIH2 Bacteria UP000019431 644454602, 586605334 AHJ67093.1 WP_025317987.1 603 610 yes 1888854 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35621, 1223523 Streptomyces mobaraensis, Streptomyces mobaraensis NBRC 13819 = DSM 40847 Bacteria UP000011740 491086762, 453051280 EME98791.1 WP_004948376.1 fig|1223523.3.peg.4015 603 608 yes 1888855 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 310037 Acaryochloris sp. CCMEE 5410 Bacteria 498155323 WP_010469479.1 455 458 yes 1888856 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 147268, 717773 Thioalkalimicrobium cyclicum, Thioalkalimicrobium cyclicum ALM1 Bacteria UP000009232 503602047, 333965586 AEG32352.1 WP_013836123.1 fig|717773.3.peg.1608 619 625 yes 1888857 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1280957 Escherichia coli, Escherichia coli HVH 2 (4-6943160) Bacteria UP000036210, UP000016348 545156883, 534539535 EQM99276.1 WP_021511996.1 626 631 yes 1888858 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 577649 Wigglesworthia glossinidia endosymbiont of Glossina fuscipes Bacteria 215479241 ACJ67191.1 397 397 no 1888859 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 860, 546275 Fusobacterium periodonticum, Fusobacterium periodonticum ATCC 33693 Bacteria UP000003748 492809219, 291380119 EFE87637.1 WP_005971082.1 433 433 yes 1888860 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82789 Agrobacterium sp. ATCC 31749 Bacteria UP000003574 493354076, 333794775 EGL66107.1 WP_006310712.1 598 607 yes 1888861 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1325472 halophilic archaeon J07HX5 Archaea UP000053694 541179744 ERG88341.1 U1P880 U1P880_9EURY 357 386 yes 1888862 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 102235, 292563 Cyanobacterium stanieri, Cyanobacterium stanieri PCC 7202 Bacteria UP000010483 505036551, 428688478 AFZ48338.1 WP_015223653.1 fig|292563.3.peg.2499 458 461 yes 1888863 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 517722 Citromicrobium sp. JLT1363 Bacteria 498094471 WP_010408627.1 624 631 yes 1888864 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61624, 1036673 Bacillus mucilaginosus, Paenibacillus mucilaginosus KNP414 Bacteria UP000006620 503680181, 336295988 AEI39091.1 WP_013914257.1 fig|1036673.3.peg.418 597 607 yes 1888865 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53329 Desulfospira joergensenii Bacteria 550913481 WP_022666479.1 422 437 yes 1888866 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 1328429 Klebsiella oxytoca, Klebsiella oxytoca MGH 28 Bacteria UP000030350, UP000017324 556477524, 555165985 ESN09132.1 WP_023329111.1 626 631 yes 1888867 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 648 Aeromonas punctata Bacteria UP000054115 498358507 WP_010672663.1 645 663 yes 1888868 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1570330, 1423, 1126211, 1155777 Bacillus sp. BH072, Bacillus subtilis, Bacillus amyloliquefaciens Y2, Bacillus amyloliquefaciens subsp. plantarum YAU B9601-Y2 Bacteria UP000031881, UP000030083, UP000002878, UP000007598 504230145, 749172021, 672874379, 387171485, 380497789 AJE77876.1, KFI16805.1, AFJ60946.1 WP_014417247.1 fig|1155777.3.peg.854, fig|1126211.3.peg.855 590 590 yes 1888869 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305, 859656 Ralstonia solanacearum, Ralstonia solanacearum CFBP2957 Bacteria UP000029286, UP000008677 502972279, 299073155 WP_013207255.1 629 631 yes 1888870 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 32054, 1170562 Calothrix parietina, Calothrix sp. PCC 6303 Bacteria UP000010477 505009255, 428233912 AFY99701.1 WP_015196357.1 fig|1170562.3.peg.674 457 459 yes 1888871 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144306 Rhizobium sp. AP16 Bacteria UP000006490 494963218, 397727781 EJK88205.1 WP_007689244.1 fig|1144306.3.peg.375 601 608 yes 1888872 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1321368 Xanthomonas sp. 97M Bacteria 551352773 WP_022972134.1 261 261 no 1888873 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1321368 Xanthomonas sp. 97M Bacteria 551352774 WP_022972135.1 355 357 no 1888874 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375 Bradyrhizobium japonicum Bacteria UP000030904 517470296 WP_018640994.1 623 632 yes 1888875 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2378, 1123288, 411922 Sporomusa ovata, Sporomusa ovata DSM 2662, Sporomusa sp. An4 Bacteria UP000015521, UP000049855 544742575, 530348598, 808676597 EQB24561.1 WP_021171468.1 431 433 yes 1888876 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 481139 Bartonella rattaustraliani Bacteria 518053530 WP_019223738.1 602 611 yes 1888877 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 253 254 no 1888878 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 51229 Wigglesworthia glossinidia Bacteria 456651469 AGG38086.1 153 153 no 1888879 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 480 482 yes 1888880 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 280240 Nocardiopsis baichengensis Bacteria 516126171 WP_017556751.1 552 554 yes 1888881 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 546, 1400137 Citrobacter freundii, Citrobacter freundii UCI 32 Bacteria UP000030582, UP000022317 696370652, 575561433 ETX61188.1 WP_032945653.1 626 632 yes 1888882 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 442, 1224746 Gluconobacter oxydans, Gluconobacter oxydans H24 Bacteria UP000000223 504885265, 411026750 AFW00005.1 WP_015072367.1 fig|1131253.3.peg.128, fig|1224746.3.peg.400 605 631 yes 1888883 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144329 Pseudomonas sp. GM33 Bacteria UP000007274 495252698, 398150262 EJM38865.1 WP_007977453.1 fig|1144329.3.peg.4477 627 629 yes 1888884 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 561, 656449 Escherichia coli TW10509 Bacteria UP000004721 447199638, 323974194 EGB69326.1 WP_001276894.1 fig|656449.3.peg.5177, fig|754332.3.peg.4018 626 631 yes 1888885 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 754327 Escherichia sp. TW09231 Bacteria 447199639 WP_001276895.1 626 631 yes 1888886 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444102, 1280937, 1182726 Escherichia coli, Escherichia coli 5-366-08_S1_C3, Escherichia coli EC096/10, Escherichia coli KTE147 Bacteria UP000036210, UP000027912, UP000019285, UP000010673 447199635, 658730231, 582993416, 431407255 KEJ71249.1, EWC54101.1, ELG90472.1 WP_001276891.1 fig|1230480.3.peg.3324, fig|1308982.3.peg.4649, fig|1182726.3.peg.2837 626 631 yes 1888887 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 656435 Escherichia coli, Escherichia coli TA124 Bacteria UP000036210, UP000004355 447199636, 371592399 EHN81305.1 WP_001276892.1 fig|656435.3.peg.4515 626 631 yes 1888888 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384, 754762 Rhizobium leguminosarum, Rhizobium leguminosarum bv. trifolii WSM2297 Bacteria UP000005732 489672611, 393184062 EJC84099.1 WP_003576864.1 601 608 yes 1888889 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 208962 Escherichia albertii Bacteria UP000066054 447199631 WP_001276887.1 626 631 yes 1888890 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 283699 Pseudoalteromonas sp. Bsw20308 Bacteria UP000011899 494620531, 410804977 EKS11009.1 WP_007378755.1 fig|283699.3.peg.3795 645 650 yes 1888891 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1292020 Dietzia sp. UCD-THP Bacteria UP000019757 602237757 EYT61103.1 565 570 yes 1888892 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 195, 1183380, 1412896, 1273173, 1242865, 887310, 887311, 887309, 887306, 887305, 887303, 887304, 887302, 887301, 887300, 887299, 887282, 887294, 887292, 887290, 887288, 887321, 887319, 887320, 887318, 887315, 887316, 1437818, 1367491 Campylobacter coli, Campylobacter coli RM5611, Campylobacter coli K3, Campylobacter coli CVM N29710, Campylobacter coli CVM N29716, Campylobacter coli H8, Campylobacter coli H9, Campylobacter coli H6, Campylobacter coli LMG 23344, Campylobacter coli LMG 23342, Campylobacter coli LMG 23336, Campylobacter coli LMG 23341, Campylobacter coli LMG 9854, Campylobacter coli 37/05, Campylobacter coli 317/04, Campylobacter coli 202/04, Campylobacter coli 132-6, Campylobacter coli 1891, Campylobacter coli 1148, Campylobacter coli 1091, Campylobacter coli 80352, Campylobacter coli 2698, Campylobacter coli 2688, Campylobacter coli 2692, Campylobacter coli 2685, Campylobacter coli 2548, Campylobacter coli 2553, Campylobacter coli IPSID-1, Campylobacter coli 76339 Bacteria UP000062643, UP000019444, UP000018579, UP000016463, UP000016499, UP000004082, UP000004403, UP000004100, UP000002948, UP000003382, UP000005517, UP000003820, UP000004143, UP000003247, UP000003872, UP000003437, UP000005478, UP000004940, UP000003453, UP000003867, UP000005511, UP000005195, UP000004635, UP000005199, UP000004187, UP000004766, UP000006025, UP000028882, UP000015930 488875026, 769548623, 589295778, 564604681, 540366513, 540154476, 380590004, 380588703, 380584698, 380581692, 380575590, 380574975, 380573390, 380571173, 380570443, 380570185, 380561833, 380550431, 380549546, 380544708, 380541594, 380539560, 380533157, 380531083, 380530205, 380527602, 380524539, 380524504, 577868938, 532690566 AJW57903.1, AHK75516.1, ETC93847.1, AGV10370.1, ERF99503.1, EIB11037.1, EIB09808.1, EIB06103.1, EIB03408.1, EIA97664.1, EIA97063.1, EIA95537.1, EIA93580.1, EIA92867.1, EIA92615.1, EIA84741.1, EIA74093.1, EIA73338.1, EIA68720.1, EIA65852.1, EIA63921.1, EIA58113.1, EIA56120.1, EIA55296.1, EIA52963.1, EIA50147.1, EIA50114.1 WP_002787251.1 fig|887292.3.peg.1480, fig|887290.3.peg.505, fig|887316.3.peg.1332, fig|887303.3.peg.520, fig|887319.3.peg.535, fig|887294.3.peg.1468, fig|887288.3.peg.995, fig|887299.3.peg.1251, fig|887305.3.peg.1259, fig|887315.3.peg.52, fig|887306.3.peg.1472, fig|887304.3.peg.1338, fig|887302.3.peg.915, fig|887320.3.peg.1001, fig|887318.3.peg.536, fig|887282.3.peg.1420, fig|887309.3.peg.1075, fig|887301.3.peg.273, fig|887321.3.peg.517, fig|887310.3.peg.725, fig|887300.3.peg.485, fig|887311.3.peg.1216 429 430 yes 1888893 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78331, 1205677 Mycobacterium canettii, Mycobacterium canettii CIPT 140070017 Bacteria UP000010807 505105043, 432165025 WP_015292145.1 544 547 yes 1888894 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 548, 1439323, 1439322, 1400138, 1400139, 1400143, 1400144, 1400145, 935296 Enterobacter aerogenes, Enterobacter aerogenes MGH-78, Enterobacter aerogenes MGH-77, Enterobacter aerogenes UCI 15, Enterobacter aerogenes UCI 16, Enterobacter aerogenes UCI 46, Enterobacter aerogenes UCI 47, Enterobacter aerogenes UCI 48, Enterobacter aerogenes EA1509E Bacteria UP000056714, UP000027231, UP000027547, UP000022913, UP000021680, UP000022253, UP000019837, UP000022314, UP000011170 505181713, 838614746, 822785297, 822765553, 822722152, 822717657, 822709518, 822699064, 822687326, 771137448, 770989957, 635747588, 635742291, 578236797, 578233980, 578186347, 578182967, 578170000, 443904589 KLV98966.1, KLF44089.1, KLF24549.1, KLE81733.1, KLE77314.1, KLE69222.1, KLE58923.1, KLE47339.1, KJM98919.1, KJL79704.1, KDF29201.1, KDF23952.1, EUL96922.1, EUL94113.1, EUL46650.1, EUL43286.1, EUL30354.1 WP_015368815.1 fig|935296.3.peg.3643 626 631 yes 1888895 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 859, 1441735 Fusobacterium necrophorum, Fusobacterium necrophorum DAB Bacteria UP000027069 737954691, 635322723 KDE71553.1 WP_035918204.1 433 433 yes 1888896 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1239, 1262914 Phascolarctobacterium sp. CAG:207 Bacteria UP000014944 545589411, 524395815 WP_021718114.1 433 433 yes 1888897 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294, 1042209 Pseudomonas fluorescens, Pseudomonas fluorescens HK44 Bacteria UP000060991, UP000022611 518521272, 589148950 EXF95141.1 WP_019691479.1 628 629 yes 1888898 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1402 Bacillus licheniformis Bacteria UP000036721 516044416, 768327560 KJH59509.1 WP_017474999.1 591 591 yes 1888899 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1681, 500634, 484020, 398513 Bifidobacterium bifidum, Bifidobacterium bifidum DSM 20456, Bifidobacterium bifidum BGN4, Bifidobacterium bifidum NCIMB 41171 Bacteria UP000035497, UP000035063, UP000006173, UP000002776 489908743, 827579649, 827575249, 672946829, 542987992, 389889985, 313132230, 781872931 KLN82795.1, KLN78429.1, KFI42557.1, ERI83972.1, AFL04052.1, EFR49847.1 WP_003812161.1 fig|398513.5.peg.1141, fig|484020.3.peg.454 638 918 yes 1888900 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 489653 Neisseria lactamica 020-06 Bacteria UP000008723 313005151 fig|489653.3.peg.392 625 671 yes 1888901 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265 Ruminococcus flavefaciens Bacteria 497671683 WP_009985867.1 437 437 yes 1888902 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 32008, 1468409, 1249661, 441157 Burkholderia sp. 2002721687, Burkholderia thailandensis MSMB121, Burkholderia thailandensis MSMB43 Bacteria UP000032645, UP000013303, UP000004682 492895863, 773063600, 484584909, 390929897 AJY41501.1, AGK46534.1, EIP87299.1 WP_006026269.1 fig|1249661.3.peg.2646 647 648 yes 1888903 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553151 Pseudomonas pelagia Bacteria 551341982 WP_022961394.1 626 627 yes 1888904 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913078 Salmonella enterica subsp. enterica serovar Minnesota str. A4-603 Bacteria UP000004989 353604358 EHC59164.1 fig|913078.3.peg.4306 92 98 no 1888905 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 1211025 Enterobacter cloacae, Enterobacter cloacae subsp. cloacae ENHKU01 Bacteria UP000036177, UP000003928 504694972, 400173289 AFP68138.1 WP_014882074.1 fig|1211025.3.peg.237 626 631 yes 1888906 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28187, 574087 Acetohalobium arabaticum, Acetohalobium arabaticum DSM 5501 Bacteria UP000001661 503042767, 302203619 ADL12297.1 WP_013277743.1 fig|574087.3.peg.783 422 426 yes 1888907 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 574087 Acetohalobium arabaticum DSM 5501 Bacteria UP000001661 302203620 ADL12298.1 fig|574087.3.peg.784 415 425 no 1888908 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 653685, 1458206, 1423, 1415165, 1177186 Bacillus amyloliquefaciens subsp. plantarum NJN6, Bacillus subtilis, Bacillus amyloliquefaciens LFB112, Bacillus amyloliquefaciens subsp. plantarum M27 Bacteria UP000033042, UP000030083, UP000018739, UP000006750 489247276, 808332656, 700305466, 566055645, 407074664 AKD29039.1, AIU76346.1, AHC41393.1, EKE47654.1 WP_003155433.1 fig|1177186.3.peg.3129 590 590 yes 1888909 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 278137 Mycobacterium sp. Spyr1 Bacteria UP000008916 315260070 ADT96811.1 fig|278137.3.peg.308, fig|350054.11.peg.769 524 525 yes 1888910 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1218582 Leptospira kirschneri serovar Valbuzzi str. Duyster Bacteria UP000011987 463287464 EMJ57239.1 fig|1218582.3.peg.1401 433 433 yes 1888911 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280668 Butyrivibrio sp. XPD2006 Bacteria 551019507 WP_022763678.1 439 441 yes 1888912 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217697 Acinetobacter sp. NIPH 1847 Bacteria UP000013106 491368460, 480173849 ENX10379.1 WP_005226358.1 fig|1217697.3.peg.95 626 631 yes 1888913 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1007115 gamma proteobacterium SCGC AAA076-D13 Bacteria 518870126 WP_020026002.1 621 622 yes 1888914 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 675635 Pseudonocardia dioxanivorans CB1190 Bacteria UP000007809 326954573 AEA28270.1 fig|675635.11.peg.6245 551 564 yes 1888915 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1517, 580327 Thermoanaerobacterium thermosaccharolyticum, Thermoanaerobacterium thermosaccharolyticum DSM 571 Bacteria UP000001626 503062494, 302777942 ADL68501.1 WP_013297470.1 fig|580327.3.peg.1112 432 433 yes 1888916 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1404, 1006007 Bacillus megaterium, Bacillus megaterium WSH-002 Bacteria UP000036135, UP000001283 504274703, 345446657 AEN91674.1 WP_014461805.1 fig|1006007.3.peg.4888 589 589 yes 1888917 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 885 yes 1888918 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158056 Streptomyces sp. PRh5 Bacteria UP000019949 740105706, 594131105 EXU66364.1 WP_037954691.1 588 589 yes 1888919 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1246995 Actinoplanes friuliensis DSM 7358 Bacteria UP000017746 556031986 AGZ39233.1 521 522 yes 1888920 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68280, 653045 Streptomyces violaceusniger, Streptomyces violaceusniger Tu 4113 Bacteria UP000053413, UP000008703 503827931, 344042746 AEM88471.1 WP_014061925.1 586 587 yes 1888921 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1930, 680198 Streptomyces scabiei, Streptomyces scabiei 87.22 Bacteria UP000028707, UP000001444 502767302, 672151751, 260648578 KFG07319.1 WP_013002286.1 fig|680198.5.peg.4547 595 614 yes 1888922 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1173026 Gloeocapsa sp. PCC 7428 Bacteria UP000010476 504999650, 428262929 AFZ28875.1 WP_015186752.1 fig|1173026.3.peg.288 455 457 yes 1888923 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 629268 Pseudomonas syringae pv. aptata str. DSM 50252 Bacteria UP000005484 330982835 EGH80938.1 314 314 no 1888924 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 427 427 yes 1888925 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935595 Neisseria meningitidis M01-240013 Bacteria UP000005529 325143598 EGC65918.1 fig|935595.3.peg.2666 625 671 yes 1888926 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 3352 Pinus taeda Plants 383163266 AFG64366.1 87 87 no 1888927 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 452 455 yes 1888928 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287273 Mesorhizobium sp. LNJC391B00 Bacteria UP000020217 563541575, 563104389 ESY28881.1 WP_023747631.1 596 611 yes 1888929 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 479 482 yes 1888930 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262995 Firmicutes bacterium CAG:646 Environmental samples UP000018386 547275294, 524163377 WP_022009066.1 432 433 yes 1888931 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 879, 1121448 Desulfovibrio gigas, Desulfovibrio gigas DSM 1382 Bacteria UP000016587 545652937, 544199065 AGW13565.1 WP_021760436.1 419 426 no 1888932 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116058 Escherichia coli, Escherichia coli MP021017.2 Bacteria UP000036210, UP000012300 487448438, 476066293 EMU90826.1 WP_001691288.1 fig|1116058.3.peg.4725 626 631 yes 1888933 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 435, 1457393 Acetobacter aceti, Acetobacter aceti 1023 Bacteria UP000027010 757525469, 635175534 KDE19812.1 WP_042787918.1 606 625 yes 1888934 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1310854 Acinetobacter baumannii 24812_10 Bacteria UP000020156 589229338 EXG72782.1 246 246 no 1888935 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1310854 Acinetobacter baumannii 24812_10 Bacteria UP000020156 589229339 EXG72783.1 379 383 no 1888936 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262862 Coprococcus sp. CAG:131 Environmental samples UP000017923 547806447, 524432488 WP_022215820.1 435 436 yes 1888937 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287640 Anaerococcus obesiensis Bacteria 517947316 WP_019117524.1 431 431 yes 1888938 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 416586 Selenomonas sp. WG Bacteria 518371439 WP_019541646.1 434 435 yes 1888939 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1266370 Nitrospina gracilis 3/211 Bacteria UP000011704 451762235 fig|1266370.3.peg.966 635 637 yes 1888940 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 291644, 1121101, 1262737 Bacteroides salyersiae, Bacteroides salyersiae DSM 18765, Bacteroides sp. CAG:189 Bacteria, Environmental samples UP000013207, UP000018406 492712620, 482600548, 524069176 EOA48706.1 WP_005931501.1 fig|1121101.3.peg.3253 564 564 yes 1888941 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262880 Eubacterium sp. CAG:156 Environmental samples UP000018124 547469493, 524266267 WP_022088300.1 436 436 yes 1888942 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913082 Salmonella enterica subsp. enterica serovar Senftenberg str. A4-543 Bacteria UP000005065 353635319 EHC81666.1 182 200 no 1888943 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1003191, 1003192, 749930 Salmonella enterica, Salmonella enterica subsp. enterica serovar Tennessee str. TXSC_TXSC08-19, Salmonella enterica subsp. enterica serovar Tennessee str. TXSC_TXSC08-21, Salmonella enterica subsp. enterica serovar Tennessee str. 4535 Bacteria UP000054489, UP000017446, UP000017325, UP000024931 446030550, 601102320, 554078034, 444830331 AHN78506.1, ESF21632.1, ELX57580.1 WP_000108405.1 626 631 yes 1888944 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 59201, 749964, 749961, 1124966, 749962, 749960, 749965, 1147753 Salmonella enterica, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Senftenberg str. 316235162, Salmonella enterica subsp. enterica serovar Senftenberg str. 423984-2, Salmonella enterica subsp. enterica serovar Senftenberg str. 604314, Salmonella enterica subsp. enterica serovar Senftenberg str. NC_MB012510-0038, Salmonella enterica subsp. enterica serovar Senftenberg str. 423984-1, Salmonella enterica subsp. enterica serovar Senftenberg str. 361154004, Salmonella enterica subsp. enterica serovar Senftenberg str. SS209 Bacteria UP000054489, UP000033855, UP000017572, UP000017269, UP000017431, UP000017612, UP000017447, UP000017449, UP000003726 446030551, 735830190, 735824188, 735816799, 735815591, 735804819, 735800336, 735797543, 554223332, 554200236, 554106595, 553566753, 553490344, 553476237, 379982677 KHP99564.1, KHP93633.1, KHP86298.1, KHP85114.1, KHP74473.1, KHP70058.1, KHP67344.1, ESG60964.1, ESG38662.1, ESF47990.1, ESC88777.1, ESC14296.1, ESC00545.1 WP_000108406.1 fig|1147753.3.peg.4956 626 631 yes 1888945 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 126385, 1256990 Providencia alcalifaciens, Providencia alcalifaciens RIMD 1656011 Bacteria UP000022107 739105499, 577065198 EUD02066.1 WP_036975958.1 623 655 yes 1888946 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 515617 Mycobacterium tuberculosis T92 Bacteria UP000005728 289689494 EFD56923.1 511 513 yes 1888947 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1329834 Enterobacter sp. MGH 38 Bacteria UP000017599 556472384, 555142258 ESM85000.1 WP_023324000.1 626 631 yes 1888948 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 471, 1217654 Acinetobacter calcoaceticus, Acinetobacter calcoaceticus NIPH 13 Bacteria UP000032475, UP000013043 490778499, 479857782 ENU10058.1 WP_004640685.1 fig|1217654.3.peg.1068 621 625 yes 1888949 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317, 205918 Pseudomonas syringae, Pseudomonas syringae pv. syringae B728a Bacteria UP000028642, UP000000426 499585696, 66043811, 63254518, 75503649 AAY35614.1 WP_011266479.1, YP_233652.1 Q4ZZ08 THIC_PSEU2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 882849 fig|205918.4.peg.877 627 629 yes 1888950 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 889211 Erwinia amylovora IL-5 Bacteria 312170807 631 644 yes 1888951 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935546 Mesorhizobium loti NZP2037 Bacteria 474421416 605 619 yes 1888952 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39152, 1053692 Methanococcus maripaludis, Methanococcus maripaludis X1 Archaea UP000008889 503764565, 339903637 AEK19079.1 WP_013998641.1 G0H1S2 G0H1S2_METMI 426 426 yes 1888953 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29497 Vibrio splendidus Bacteria UP000050463 515648948 WP_017081548.1 640 649 yes 1888954 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4555 Setaria italica Plants UP000004995 514814828 XP_004982183.1 542 642 yes 1888955 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1513, 1231072 Clostridium tetani, Clostridium tetani 12124569 Bacteria UP000029689, UP000017784 557697370, 557604807, 557255508 WP_023437672.1, YP_008772918.1 89 89 no 1888956 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43771, 1267754 Corynebacterium urealyticum, Corynebacterium urealyticum DSM 7111 Bacteria UP000011824 505194564, 448277253 AGE36677.1 WP_015381666.1 fig|1267754.3.peg.1113 599 606 yes 1888957 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 611 614 yes 1888958 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 665097, 1161919 Erwinia sp. CECT 7348, Erwinia piriflorinigrans CFBP 5888 Bacteria UP000018217 562746282, 560110327 WP_023653407.1 631 644 yes 1888959 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1470591 Sphingomonas sp. RIT328 Bacteria UP000024210 739681240, 612090708 EZP49251.1 WP_037536005.1 612 618 yes 1888960 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1073567 Streptomyces sp. TOR3209 Bacteria 518154455 WP_019324663.1 600 603 yes 1888961 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1491, 929508, 1440058, 1443117 Clostridium botulinum, Clostridium botulinum V891, Clostridium botulinum C/D str. Sp77, Clostridium botulinum D str. 16868 Bacteria UP000030128, UP000035658, UP000027899, UP000027828 518108008, 835632889, 658089359, 658084571 KLU76079.1, KEI02028.1, KEH97435.1 WP_019278216.1 437 437 yes 1888962 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 878, 596151 Desulfovibrio fructosovorans, Desulfovibrio fructosovorans JJ Bacteria UP000006250 492841166, 302490349 EFL50260.1 WP_005995120.1 419 437 no 1888963 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 992183, 992179, 992165, 992164, 992163, 992158, 992148, 992142, 992131, 992130 Yersinia pestis PY-102, Yersinia pestis PY-98, Yersinia pestis PY-65, Yersinia pestis PY-64, Yersinia pestis PY-63, Yersinia pestis PY-56, Yersinia pestis PY-36, Yersinia pestis PY-16, Yersinia pestis PY-05, Yersinia pestis PY-04 Bacteria UP000003430, UP000003219, UP000004196, UP000004572, UP000003774, UP000005712, UP000004173, UP000003520, UP000004229, UP000005967 391722843, 391693527, 391623308, 391611762, 391610255, 391581466, 391531809, 391501415, 391437703, 391436503 EIT52603.1, EIT26268.1, EIS64123.1, EIS53906.1, EIS52563.1, EIS27346.1, EIR83270.1, EIR55823.1, EIQ98535.1, EIQ97452.1 fig|992163.3.peg.4056, fig|992153.3.peg.4065, fig|992179.3.peg.3871, fig|992135.3.peg.3878, fig|992138.3.peg.4261, fig|992129.3.peg.4097, fig|992164.3.peg.4059, fig|992148.3.peg.4106, fig|992182.3.peg.3827, fig|992161.3.peg.4064, fig|992131.3.peg.3889, fig|992165.3.peg.4064, fig|992143.3.peg.3805, fig|992181.3.peg.3846, fig|992142.3.peg.3899, fig|992134.3.peg.4201, fig|992172.3.peg.3857, fig|992127.3.peg.4156, fig|992151.3.peg.3895, fig|992184.3.peg.3939, fig|992183.3.peg.4077, fig|992132.3.peg.4159, fig|992130.3.peg.4163, fig|992152.3.peg.4100, fig|992169.3.peg.3733, fig|992168.3.peg.3783, fig|992175.3.peg.3981, fig|992141.3.peg.4150, fig|992128.3.peg.4055, fig|992155.3.peg.4041, fig|992158.3.peg.3888 420 431 yes 1888964 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2198, 368407 Methanoculleus marisnigri, Methanoculleus marisnigri JR1 Archaea UP000054598, UP000002146 500168484, 125860799 ABN55988.1 WP_011842909.1 A3CRI8 A3CRI8_METMJ fig|368407.6.peg.53 413 426 no 1888965 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992165, 992152, 992142, 992138, 992130 Yersinia pestis, Yersinia pestis PY-65, Yersinia pestis PY-47, Yersinia pestis PY-16, Yersinia pestis PY-12, Yersinia pestis PY-04 Bacteria UP000000815 UP000031825, UP000004196, UP000005348, UP000003520, UP000005382, UP000005967 488299847, 391623327, 391550385, 391501430, 391471534, 391436529 EIS64140.1, EIS00006.1, EIR55836.1, EIR29088.1, EIQ97475.1 WP_002371055.1 205 224 no 1888966 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262773 Clostridium sp. CAG:122 Environmental samples UP000017991 547282059, 524170405 WP_022015433.1 434 435 yes 1888967 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 373391 Thiomicrospira halophila Bacteria 518735257 WP_019894969.1 631 639 yes 1888968 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1184 Leptolyngbya boryana Bacteria 515858671 WP_017289299.1 454 457 yes 1888969 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 451 464 yes 1888970 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 28901, 1029986 Salmonella enterica, Salmonella enterica subsp. enterica serovar Enteritidis str. 50-5646 Bacteria UP000054489, UP000010956 487603684, 435339901 ELP08601.1 WP_001732113.1 fig|1029986.3.peg.262 259 261 no 1888971 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 311230, 1171375 Burkholderia terrae, Burkholderia terrae BS001 Bacteria 494859438, 389936591 EIM98478.1 WP_007585538.1 fig|1171375.3.peg.4945 642 643 yes 1888972 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 222534 Frankia sp. BMG5.12 Bacteria 517467434 WP_018638146.1 600 611 yes 1888973 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 386428 Pseudoalteromonas sp. BSi20480 Bacteria UP000003342 495405547, 358044169 WP_008130246.1 fig|386428.3.peg.2144 645 650 yes 1888974 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1270, 596312 Micrococcus luteus, Micrococcus luteus SK58 Bacteria UP000032023, UP000002933 490271486, 289556878 EFD50211.1 WP_004167640.1 591 607 yes 1888975 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1391991, 1401690 Mycobacterium avium subsp. avium 10-9275, Mycobacterium avium subsp. silvaticum ATCC 49884 Bacteria UP000018568, UP000018526 564169100, 564161423 ETB11674.1, ETB05118.1 466 467 yes 1888976 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29465, 936591, 1128111, 866776 Veillonella sp. ICM51a, Veillonella atypica KON, Veillonella atypica ACS-049-V-Sch6 Bacteria UP000020651, UP000010412, UP000004211 491520546, 576671388, 429176915, 302513685 EUB25076.1, EKY18265.1, EFL55704.1 WP_005378177.1 fig|1128111.3.peg.1504, fig|866776.4.peg.1317 434 434 yes 1888977 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 310575, 1424334 Tetrathiobacter mimigardefordensis, Advenella kashmirensis W13003 Bacteria UP000018733 566135855, 565406660 ETF01000.1 WP_024006352.1 636 637 yes 1888978 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 997332 Salmonella enterica, Salmonella enterica subsp. enterica serovar Meleagridis str. 0047 Bacteria UP000054489, UP000017360 555228917, 554187000 ESG25906.1 WP_023216632.1 626 631 yes 1888979 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2352, 717231 Flexistipes sinusarabici, Flexistipes sinusarabici DSM 4947 Bacteria UP000006621 503651170, 336105914 AEI13732.1 WP_013885246.1 fig|717231.3.peg.34 421 421 yes 1888980 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1395589, 1193029, 1049939, 1049922, 1049936, 1049928, 1193042, 1240691, 1240692, 1218574, 1049935, 1193014, 1001591, 267671 Leptospira interrogans serovar Linhai str. 56609, Leptospira interrogans serovar Pyrogenes str. 200701872, Leptospira interrogans str. UI 13372, Leptospira interrogans serovar Medanensis str. UT053, Leptospira interrogans str. UI 09600, Leptospira interrogans serovar Pyrogenes str. L0374, Leptospira interrogans str. Kito, Leptospira interrogans serovar Pomona str. CSL4002, Leptospira interrogans serovar Pomona str. CSL10083, Leptospira interrogans serovar Pomona str. Fox 32256, Leptospira interrogans str. UI 08452, Leptospira interrogans serovar Canicola str. Fiocruz LV133, Leptospira interrogans str. C10069, Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Bacteria UP000032263, UP000012117, UP000012162, UP000012088, UP000012121, UP000012137, UP000011938, UP000011878, UP000011986, UP000011733, UP000001335, UP000006273, UP000006313, UP000007037 764086146, 464476652, 464449216, 464300606, 464277140, 464219549, 463354809, 463292312, 461485851, 455668061, 410788298, 410012086, 409952440, 45601758 AJR15368.1, EMP05019.1, EMO92256.1, EMN92844.1, EMN75452.1, EMN32399.1, EMK17686.1, EMJ61534.1, EMI70697.1, EMF33310.1, EKR82020.1, EKO70191.1, EKO06953.1, AAS71238.1 Q72NZ8 THIC_LEPIC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 661326 fig|1291365.3.peg.115, fig|1049907.3.peg.640, fig|996827.3.peg.2004, fig|1291364.3.peg.3901, fig|996859.3.peg.129, fig|1001598.3.peg.2040, fig|1049795.3.peg.3497, fig|996839.3.peg.1389, fig|1049932.3.peg.1014, fig|996821.3.peg.812, fig|996862.3.peg.1823, fig|1085542.3.peg.1104, fig|996858.3.peg.1945, fig|996838.3.peg.1209, fig|1291339.3.peg.215, fig|1001602.3.peg.4185, fig|1193060.3.peg.2208, fig|996814.3.peg.1865, fig|996824.3.peg.2063, fig|996854.3.peg.1358, fig|1049806.3.peg.1973, fig|996853.3.peg.2085, fig|1049802.3.peg.1366, fig|1291353.3.peg.2073, fig|1291327.3.peg.3107, fig|1049938.3.peg.3667, fig|1291316.3.peg.4373, fig|996845.3.peg.3327, fig|996846.3.peg.3151, fig|996847.3.peg.962, fig|996828.3.peg.1571, fig|1049940.3.peg.2067, fig|1291347.3.peg.478, fig|1049820.3.peg.898, fig|996840.3.peg.1766, fig|996831.3.peg.2209, fig|1291348.3.peg.2896, fig|1085543.3.peg.2547, fig|1291336.3.peg.678, fig|996842.3.peg.1990, fig|996860.3.peg.2153, fig|996822.3.peg.1419, fig|996825.3.peg.2512, fig|1193029.3.peg.5343, fig|1291340.3.peg.2910, fig|1049924.3.peg.5530, fig|996863.3.peg.991, fig|1291345.3.peg.2419, fig|996850.3.peg.883, fig|267671.1.peg.2601, fig|996835.3.peg.2323, fig|1049921.3.peg.4152, fig|996849.3.peg.1904, fig|1049801.3.peg.1413, fig|1291343.3.peg.2225, fig|1291331.3.peg.2205, fig|1049909.3.peg.1075, fig|1291366.3.peg.3261, fig|1001987.3.peg.909, fig|1049920.3.peg.1374, fig|996843.3.peg.1433, fig|1291359.3.peg.4108, fig|1049803.3.peg.305, fig|996861.3.peg.2077, fig|996834.3.peg.1129, fig|1001587.6.peg.128, fig|1240692.3.peg.572, fig|1291309.3.peg.901, fig|996811.3.peg.1597, fig|1049903.3.peg.912, fig|1291317.3.peg.3348, fig|1193014.3.peg.2329, fig|996830.3.peg.1058, fig|1001591.3.peg.1477, fig|996836.3.peg.3269, fig|1291335.3.peg.1751, fig|1049821.3.peg.807, fig|1291334.3.peg.3558, fig|1291346.3.peg.4439, fig|1049935.3.peg.749, fig|1193042.3.peg.3836, fig|1049936.3.peg.2259, fig|1291360.3.peg.715, fig|1218574.3.peg.2494, fig|1291319.3.peg.2338, fig|1291307.3.peg.409, fig|1049819.3.peg.4049, fig|996851.3.peg.2089, fig|1291332.3.peg.406, fig|1049931.3.peg.1146, fig|1049928.3.peg.624, fig|996809.3.peg.3370, fig|996816.3.peg.4453, fig|996833.3.peg.616, fig|1240691.3.peg.2583, fig|996823.3.peg.410, fig|996856.3.peg.2457, fig|996848.3.peg.442, fig|1049905.3.peg.1563, fig|1001986.3.peg.3725, fig|1049908.3.peg.769, fig|996829.3.peg.2846, fig|1049922.3.peg.3267, fig|1049937.3.peg.5644, fig|1291341.3.peg.296, fig|1193039.3.peg.3102, fig|1049902.3.peg.1103, fig|1049926.3.peg.2337 505 515 yes 1888981 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 614 620 yes 1888982 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262871 Dialister sp. CAG:588 Environmental samples UP000018383 548327260, 524834621 WP_022513158.1 419 420 yes 1888983 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59840, 717606 Paenibacillus curdlanolyticus, Paenibacillus curdlanolyticus YK9 Bacteria UP000005387 492906784, 304345735 EFM11569.1 WP_006037190.1 585 586 yes 1888984 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4577 Zea mays Plants UP000007305 224029027, 414871954, 414871953, 414871952 ACN33589.1 549 643 yes 1888985 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 872330 Acidithiobacillus sp. GGI-221 Bacteria UP000003197 339833402 EGQ61250.1 286 287 no 1888986 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1454585, 1454590, 1454592, 59201, 1173435, 984211, 1124924 Salmonella enterica, Salmonella enterica subsp. enterica serovar Anatum str. USDA-ARS-USMARC-1735, Salmonella enterica subsp. enterica serovar Anatum str. USDA-ARS-USMARC-1175, Salmonella enterica subsp. enterica serovar Anatum str. USDA-ARS-USMARC-1764, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000207, Salmonella enterica subsp. enterica serovar Anatum str. ATCC BAA-1592, Salmonella enterica subsp. enterica serovar Anatum str. USDA 100 Bacteria UP000054489, UP000034042, UP000032725, UP000032231, UP000033855, UP000029180, UP000017347, UP000017328 555261003, 817619451, 785746974, 764044297, 735761852, 735756080, 677857144, 605522563, 554370583 AKF91774.1, AJZ81700.1, AJQ63071.1, KHP32063.1, KHP26353.1, KFT72270.1, AHW15177.1, ESJ07312.1 WP_023243133.1 626 631 yes 1888987 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 45658, 870967 Vibrio scophthalmi, Vibrio scophthalmi LMG 19158 Bacteria UP000004349 491788613, 342793809 EGU29595.1 WP_005599957.1 640 645 yes 1888988 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 379067, 749414 Streptomyces bingchenggensis, Streptomyces bingchenggensis BCW-1 Bacteria UP000000377 503943919, 297158735 ADI08447.1 WP_014177913.1 fig|749414.3.peg.5501 582 584 yes 1888989 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 398037 Segetibacter koreensis Bacteria 517443693 WP_018614536.1 616 616 yes 1888990 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 242750, 585502 Prevotella bergensis, Prevotella bergensis DSM 17361 Bacteria UP000003160 494308318, 270333120 EFA43906.1 WP_007173727.1 527 527 yes 1888991 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 245160, 1196324 Bacillus macauensis, Bacillus macauensis ZFHKF-1 Bacteria UP000004080 494377845, 391877090 EIT85684.1 WP_007201616.1 fig|1196324.3.peg.1557 583 583 yes 1888992 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 115547 uncultured archaeon Archaea 268323083, 82617378 Q2Y4H5 Q2Y4H5_9ARCH 430 435 yes 1888993 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84030, 610130 Clostridium saccharolyticum, Clostridium saccharolyticum WM1 Bacteria UP000001662 503039240, 302198579 ADL06150.1 WP_013274216.1 fig|610130.3.peg.3915 435 435 yes 1888994 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 585394 Roseburia hominis A2-183 Bacteria UP000008178 345502663 AEN97346.1 fig|585394.18.peg.2254 457 462 yes 1888995 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 889246 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni LMG 23357 Bacteria UP000065538, UP000003297 488969726, 380619145 EIB38237.1 WP_002880677.1 fig|889246.3.peg.606 429 430 yes 1888996 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1412534 Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120685 Bacteria UP000023658 604032718 AHT56151.1 588 590 yes 1888997 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 698954, 698953 Gardnerella vaginalis 6420B, Gardnerella vaginalis 6420LIT Bacteria UP000033124 388056578, 388054639 EIK79441.1, EIK77577.1 fig|698953.3.peg.364, fig|698954.3.peg.126 608 885 yes 1888998 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 1204476 Fusobacterium nucleatum, Fusobacterium nucleatum CTI-3 Bacteria UP000017097 552909588, 551106911 ERT38064.1 WP_023039769.1 433 433 yes 1888999 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158293 Oxalobacteraceae bacterium AB_14 Bacteria 522197468 WP_020704935.1 637 638 yes 1889000 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1069620, 1200386 Neisseria meningitidis, Neisseria meningitidis NM2795, Neisseria meningitidis alpha704 Bacteria UP000050419, UP000004151, UP000009312 488170839, 402339070, 393291059 EJU74291.1 WP_002242047.1 fig|1069620.3.peg.2624, fig|1200386.3.peg.2319 625 633 yes 1889001 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 1204475 Fusobacterium nucleatum, Fusobacterium nucleatum CTI-2 Bacteria UP000017128 552917125, 551113091 ERT43918.1 WP_023040600.1 433 433 yes 1889002 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 461 462 yes 1889003 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262945 Roseburia sp. CAG:309 Environmental samples UP000018292 547940860, 524618493 WP_022342201.1 436 436 yes 1889004 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1270, 465515 Micrococcus luteus, Micrococcus luteus NCTC 2665 Bacteria UP000032023, UP000000738 497764856, 239838524 ACS30321.1 WP_010079040.1 fig|465515.12.peg.588 591 607 yes 1889005 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168697 Salinispora arenicola Bacteria 517627849 WP_018798057.1 530 530 yes 1889006 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 869212 Turneriella parva DSM 21527 Bacteria UP000006048 390613300 AFM14452.1 fig|869212.3.peg.3847 494 499 yes 1889007 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4081 Solanum lycopersicum Plants UP000004994 UP000004994 169883406, 169883405, 169883404 ACA97596.1, ACA97595.1, ACA97594.1 541 650 yes 1889008 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 28184, 1088540 Leptospira weilii, Leptospira weilii serovar Topaz str. LT2116 Bacteria UP000011770 490643193, 456861724 EMF80360.1 WP_004508188.1 68 78 no 1889009 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1496, 1151428, 1151368, 1151330, 1215070, 1215069, 1215068 Clostridium difficile, Clostridium difficile P59, Clostridium difficile F314, Clostridium difficile DA00145, Clostridium difficile T23, Clostridium difficile E15, Clostridium difficile T11 Bacteria UP000058232, UP000015700, UP000015751, UP000015776, UP000018250, UP000018285, UP000018097 545004310, 531735307, 531518456, 531370354, 549327320, 549322851, 549318500 EQK11982.1, EQI03271.1, EQG62793.1 WP_021396387.1 352 366 no 1889010 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 262489 delta proteobacterium MLMS-1 Bacteria UP000005853 93454833 EAT05083.1 450 479 yes 1889011 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 146826, 519442 Halorhabdus utahensis, Halorhabdus utahensis DSM 12940 Archaea UP000002071 506270427, 257053536, 256692299 ACV12636.1 WP_015790202.1, YP_003131369.1 C7NMJ7 C7NMJ7_HALUD 7510669 fig|519442.4.peg.145 455 481 yes 1889012 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 680, 1224742 Vibrio campbellii, Vibrio campbellii CAIM 519 = NBRC 15631 Bacteria UP000030534, UP000011224 491679728, 444238182 ELU49804.1 WP_005535870.1 fig|1224742.3.peg.4217 640 646 yes 1889013 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 64160, 868864 Desulfurobacterium thermolithotrophum, Desulfurobacterium thermolithotrophum DSM 11699 Bacteria UP000007102 503404389, 325066095 ADY74102.1 WP_013639050.1 fig|868864.3.peg.1524 434 434 yes 1889014 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151334 Clostridium difficile DA00165 Bacteria UP000015837 531383517 EQG75508.1 176 176 no 1889015 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 854 Fusobacterium russii Bacteria 551175832 WP_022818860.1 433 433 yes 1889016 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3760 Prunus persica Plants UP000006882 595836192, 595836187, 462402848, 462402847 EMJ08405.1, EMJ08404.1 XP_007207206.1, XP_007207205.1 543 648 yes 1889017 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 145263, 79929 Methanothermobacter marburgensis, Methanothermobacter marburgensis str. Marburg Archaea UP000000345 503060023, 304313937, 302587396 ADL57771.1 WP_013294999.1, YP_003849084.1 D9PU73 D9PU73_METTM 422 423 yes 1889018 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1298610 Psychrobacter sp. JCM 18903 Bacteria UP000019503 589904664 533 606 no 1889019 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 723172 Vibrio sp. F6 Bacteria 515621738 WP_017054338.1 640 656 yes 1889020 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 208216, 314260 Parvularcula bermudensis, Parvularcula bermudensis HTCC2503 Bacteria UP000001302 503065468, 303299871 ADM09470.1 WP_013300444.1 fig|314260.3.peg.1444 631 635 yes 1889021 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 443218 Mycobacterium sp. DQS39A1 Bacteria UP000009235 333480443 AEF39003.1 fig|443218.3.peg.678 554 556 yes 1889022 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1050720 Agrobacterium tumefaciens F2 Bacteria UP000004380 338824108 EGP58075.1 fig|1050720.3.peg.369 601 606 yes 1889023 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28108, 1004785 Alteromonas macleodii, Alteromonas macleodii str. 'Black Sea 11' Bacteria UP000031168, UP000006295 504809746, 407247508 AFT76693.1 WP_014996848.1 fig|1004785.3.peg.104 630 636 yes 1889024 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901 Salmonella enterica Bacteria UP000054489 583242443 WP_024157470.1 626 631 yes 1889025 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 663321 Candidatus Regiella insecticola LSR1 Bacteria UP000005726 304282555 EFL91105.1 593 604 yes 1889026 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 517574430 WP_018744638.1 530 530 yes 1889027 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56460, 925775 Xanthomonas vesicatoria, Xanthomonas vesicatoria ATCC 35937 Bacteria UP000054358, UP000003299 492836898, 325538476 EGD10152.1 WP_005990852.1 624 625 yes 1889028 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216778 Stenotrophomonas rhizophila Bacteria UP000055579 740901158, 627788591 AHY57807.1 WP_038686406.1 624 625 yes 1889029 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 228745, 648996 Thermovibrio ammonificans, Thermovibrio ammonificans HB-1 Bacteria UP000006362 503302175, 317113560 ADU96050.1 WP_013536836.1 fig|648996.5.peg.173 436 436 yes 1889030 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 296745, 986075 Caldalkalibacillus thermarum, Caldalkalibacillus thermarum TA2.A1 Bacteria UP000010716 494769144, 334180326 EGL82943.1 WP_007504552.1 590 590 yes 1889031 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 95606 Sphingomonas-like bacterium B12 Bacteria 550944371 WP_022692773.1 312 317 yes 1889032 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375288, 1235789, 1235803 Parabacteroides goldsteinii dnLKV18, Parabacteroides sp. ASF519 Bacteria UP000014140, UP000013570 498502414, 507761485, 476623527 EOS20265.1, EMZ30303.1 WP_010803116.1 fig|1235789.3.peg.955, fig|1235803.3.peg.4706 567 567 yes 1889033 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 443144 Geobacter sp. M21 Bacteria UP000002380 506318960, 251776969 ACT19550.1 WP_015838735.1 fig|443144.3.peg.3446 437 437 yes 1889034 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1329842 Enterobacter sp. BIDMC 30 Bacteria UP000022373 695753724, 578252831 EUM12914.1 WP_032679969.1 626 631 yes 1889035 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 748655 Thioalkalivibrio sp. ALgr1 Bacteria 517823200 WP_018993408.1 627 629 yes 1889036 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 297612997, 255670218 NP_001066547.2 B8YEK4 OGR1_ORYSJ Pentatricopeptide repeat-containing protein OGR1, mitochondrial {ECO:0000305} 135 142 no 1889037 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1431454, 1444073, 1444236, 1444265, 1438689, 1438685, 1438684, 1438682, 1438683, 1438680, 1438679, 1438674, 1438670, 1438671, 1438672, 1438668, 1328433, 1328446, 1328447, 1281106, 1389418, 1281044, 1328449, 1355100, 1269005, 1269002, 1269001, 1268994, 1268984, 1268983, 1268981, 1268988, 1328435, 1281266, 1281196, 1281132, 1281129, 1281117, 1281113, 1281105, 1281095, 1281087, 1281079, 1281074, 1281027, 1281021, 1280975, 1280968, 1169392, 1169391, 1169389, 1169375, 1181763, 1181757, 1181725, 1181724, 1181738, 1182735, 1169342, 1169337, 1169336, 1169327, 1182734, 1182656, 1181762, 1181726, 1169347, 1169344, 1033813, 656417, 749542, 1359206, 1432559, 1432549, 1432551, 1263075, 431946 Escherichia coli, Escherichia coli NB8, Escherichia coli 2-460-02_S1_C2, Escherichia coli 2-427-07_S4_C2, Escherichia coli 2-316-03_S4_C3, Escherichia coli UCI 51, Escherichia coli CHS 69, Escherichia coli CHS 68, Escherichia coli BIDMC 78, Escherichia coli BIDMC 79, Escherichia coli BIDMC 76, Escherichia coli BIDMC 75, Escherichia coli BIDMC 70, Escherichia coli BIDMC 62, Escherichia coli BIDMC 63, Escherichia coli BIDMC 64, Escherichia coli BIDMC 58, Escherichia coli BWH 34, Escherichia coli BIDMC 20A, Escherichia coli BIDMC 20B, Escherichia coli HVH 177 (4-2876612), Escherichia coli LAU-EC7, Escherichia coli HVH 108 (4-6924867), Escherichia coli BIDMC 38, Escherichia coli JJ1886, Escherichia coli 908691, Escherichia coli 908632, Escherichia coli 908624, Escherichia coli 908524, Escherichia coli 907701, Escherichia coli 907700, Escherichia coli 907446, Escherichia coli 907779, Escherichia coli BWH 24, Escherichia coli UMEA 3703-1, Escherichia coli UMEA 3155-1, Escherichia coli HVH 205 (4-3094677), Escherichia coli HVH 202 (4-3163997), Escherichia coli HVH 190 (4-3255514), Escherichia coli HVH 186 (4-3405044), Escherichia coli HVH 176 (4-3428664), Escherichia coli HVH 162 (4-5627982), Escherichia coli HVH 154 (4-5636698), Escherichia coli HVH 146 (4-3189767), Escherichia coli HVH 141 (4-5995973), Escherichia coli HVH 90 (4-3191362), Escherichia coli HVH 84 (4-1021478), Escherichia coli HVH 24 (4-5985145), Escherichia coli HVH 17 (4-7473087), Escherichia coli KTE150, Escherichia coli KTE148, Escherichia coli KTE139, Escherichia coli KTE109, Escherichia coli KTE217, Escherichia coli KTE211, Escherichia coli KTE175, Escherichia coli KTE173, Escherichia coli KTE192, Escherichia coli KTE165, Escherichia coli KTE23, Escherichia coli KTE18, Escherichia coli KTE17, Escherichia coli KTE6, Escherichia coli KTE162, Escherichia coli KTE49, Escherichia coli KTE216, Escherichia coli KTE178, Escherichia coli KTE28, Escherichia coli KTE25, Escherichia coli NA114, Escherichia coli M605, Escherichia coli MS 16-3, Escherichia coli ST131, Escherichia coli ISC41, Escherichia coli IS29, Escherichia coli IS35, Escherichia coli CAG:4, Escherichia coli SE15 Bacteria, Environmental samples UP000036210, UP000034317, UP000028070, UP000028023, UP000028127, UP000027545, UP000027205, UP000027503, UP000027320, UP000027497, UP000027508, UP000027567, UP000027128, UP000027570, UP000027352, UP000027499, UP000027218, UP000021032, UP000022059, UP000021871, UP000018754, UP000018759, UP000017760, UP000017399, UP000017428, UP000017564, UP000017307, UP000017357, UP000017499, UP000017267, UP000017329, UP000017563, UP000017295, UP000017157, UP000016288, UP000016266, UP000016291, UP000016139, UP000016460, UP000016022, UP000016358, UP000016076, UP000016284, UP000016402, UP000016018, UP000016133, UP000016275, UP000016370, UP000016010, UP000010615, UP000010592, UP000010566, UP000010637, UP000010543, UP000010554, UP000010568, UP000010557, UP000010694, UP000010570, UP000010616, UP000010628, UP000010626, UP000010654, UP000010630, UP000010595, UP000010652, UP000010690, UP000010700, UP000010500, UP000008885, UP000004710, UP000005366, UP000019180, UP000019182, UP000019196, UP000018186, UP000009157 447199630, 838819910, 838798912, 838743459, 838740070, 838734202, 838726991, 836409373, 816241532, 768590650, 768578073, 768564397, 767816148, 758865130, 701206895, 701204117, 672832768, 660676027, 660349223, 652127190, 652099852, 636875281, 635888118, 635876214, 635865406, 635857070, 635855611, 635840553, 635839344, 635815436, 635799360, 635799021, 635797773, 635784767, 629840451, 597600446, 575648805, 575592984, 575587895, 565501647, 564935971, 556152439, 554987849, 554514265, 553708877, 553691934, 553684714, 553641918, 553606307, 553591913, 553581275, 553366822, 550202541, 535852380, 535568966, 535299704, 535286059, 535232164, 535208843, 535170887, 535130797, 535115554, 535083658, 535053122, 534860196, 534834900, 534624428, 534590795, 431623467, 431622947, 431611649, 431539103, 431501462, 431486645, 431451900, 431433791, 431433088, 431428982, 431280801, 431270321, 431269793, 431254326, 431229605, 431088038, 431025371, 430940955, 430925732, 430919682, 333971463, 331041313, 315300737, 641687003, 576030804, 572155065, 571238562, 524547991, 281181058 KLY02088.1, KLX81274.1, KLX26557.1, KLX23206.1, KLX17387.1, KLX10265.1, KLU94854.1, KKJ99956.1, KJI24291.1, KJI11992.1, KJH98791.1, KJG96883.1, AJO86088.1, KGP45934.1, KGP43193.1, KFH77088.1, KEP15450.1, KEO36172.1, KDY40564.1, KDY14587.1, KDN08242.1, KDG68733.1, KDG56979.1, KDG46255.1, KDG37968.1, KDG36522.1, KDG21607.1, KDG20410.1, KDF96681.1, KDF80683.1, KDF80345.1, KDF79108.1, KDF66155.1, KCW94496.1, EYB46681.1, ETY47483.1, ETX92255.1, ETX87226.1, ETF13589.1, ETE30711.1, ESP40578.1, ESL32441.1, AGY86625.1, ESE24236.1, ESE08027.1, ESE01185.1, ESD60737.1, ESD26747.1, ESD12969.1, ESD02724.1, ESA93331.1, ERO93126.1, EQZ84421.1, EQX06571.1, EQU42652.1, EQU29146.1, EQT75808.1, EQT52831.1, EQT15514.1, EQS76121.1, EQS61562.1, EQS30146.1, EQS00019.1, EQQ10797.1, EQP85940.1, EQN81227.1, EQN49621.1, ELI92137.1, ELI91631.1, ELI80924.1, ELI15078.1, ELH80443.1, ELH66294.1, ELH32356.1, ELH15446.1, ELH14761.1, ELH10914.1, ELF71716.1, ELF61490.1, ELF61095.1, ELF47601.1, ELF26244.1, ELD93948.1, ELD38479.1, ELC61115.1, ELC46337.1, ELC40603.1, AEG38268.1, EGI13465.1, EFU59962.1 WP_001276886.1 fig|1182734.3.peg.4517, fig|262543.4.peg.1397, fig|941322.6.peg.4881, fig|1169327.3.peg.1772, fig|1169336.3.peg.167, fig|1169389.3.peg.4153, fig|1181762.3.peg.4893, fig|1181726.3.peg.5027, fig|1169392.3.peg.4262, fig|1169337.3.peg.4686, fig|1169375.3.peg.4165, fig|1181738.3.peg.20, fig|1181763.3.peg.251, fig|1181757.3.peg.4837, fig|1182735.3.peg.1462, fig|1169391.3.peg.4266, fig|1181725.3.peg.20, fig|1169342.3.peg.4611, fig|431946.3.peg.4005, fig|1182656.3.peg.5145, fig|1033813.3.peg.3457, fig|1169344.3.peg.291, fig|749542.3.peg.162, fig|656417.3.peg.4909, fig|1181724.3.peg.5112, fig|1169347.3.peg.4432 626 631 yes 1889038 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44752, 1195242 Rhodococcus wratislaviensis, Rhodococcus wratislaviensis IFP 2016 Bacteria UP000010548 491723301, 430777671 ELB93005.1 WP_005563842.1 fig|1195242.3.peg.2196 541 548 yes 1889039 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 263511, 165597 Crocosphaera watsonii, Crocosphaera watsonii WH 8501 Bacteria UP000003922 494514330, 67856892 EAM52132.1 WP_007303788.1 fig|165597.4.peg.932 459 459 yes 1889040 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 745411 Gallaecimonas sp. 3-C-1 Bacteria UP000006755 407197161 EKE67241.1 600 601 yes 1889041 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 582, 1239989 Morganella morganii, Morganella morganii SC01 Bacteria UP000037663, UP000006333 490362526, 721583211, 701204154, 468907458 KGZ26488.1, KGP43228.1, EMP49914.1 WP_004242289.1 620 649 yes 1889042 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 545693 Bacillus megaterium QM B1551 Bacteria UP000000935 502820208, 294347180 ADE67509.1 WP_013055184.1 fig|545693.3.peg.458 589 589 yes 1889043 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1049933 Leptospira interrogans str. L1207 Bacteria UP000012093 464243603 EMN50516.1 191 192 no 1889044 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 187493, 1208320 Thalassolituus oleivorans, Thalassolituus oleivorans R6-15 Bacteria UP000019420 643872227, 588290430 AHK15624.1 WP_025265311.1 621 632 yes 1889045 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263051 Bacteroides pectinophilus CAG:437 Environmental samples UP000018141 547961714, 524644964 WP_022361962.1 434 435 yes 1889046 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1214915 Mycobacterium smegmatis MKD8 Bacteria UP000011200 440629888 ELQ91669.1 523 524 yes 1889047 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 823, 999416 Parabacteroides distasonis, Parabacteroides distasonis CL03T12C09 Bacteria UP000006318 492473637, 409229643 EKN22515.1 WP_005857011.1 565 565 yes 1889048 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397666 alpha proteobacterium RS24 Bacteria UP000016762 545671726, 544592441 ERL46788.1 WP_021777764.1 639 642 yes 1889049 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1269, 1270 Micrococcus luteus Bacteria UP000032023 738389578, 612084567, 612068932 EZP43291.1, EZP27951.1 WP_036341386.1 591 601 yes 1889050 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547 553 yes 1889051 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310790 Acinetobacter baumannii, Acinetobacter baumannii 1179249 Bacteria UP000028632, UP000021370 691069889, 593548490 EXR32529.1 WP_032011634.1 621 625 yes 1889052 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262915 Phascolarctobacterium sp. CAG:266 Bacteria UP000014925 524384908 114 115 no 1889053 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413496, 956149, 930780, 1208662 Cronobacter sakazakii Sp291, Cronobacter sakazakii E899, Cronobacter malonaticus 507 Bacteria UP000011279, UP000054400, UP000009341 490522685, 449099947, 333953509, 426313726 AGE87981.1, EGL71449.1 WP_004388103.1 fig|1208662.3.peg.3245, fig|930780.3.peg.3317, fig|956149.6.peg.3396, fig|1159489.3.peg.756, fig|1045857.3.peg.975 626 633 yes 1889054 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 195250 Synechococcus sp. PCC 7336 Bacteria 515896802 WP_017327385.1 455 458 yes 1889055 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1294123 Sulfolobales archaeon Acd1 Archaea 519043111 WP_020198986.1 442 442 yes 1889056 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55508, 1349767 Janthinobacterium agaricidamnosum, Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628 Bacteria UP000027604 740710980, 571269941 WP_038496267.1 635 637 yes 1889057 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 1310163 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni HN-CJD07035 Bacteria UP000065538, UP000030757 544707432, 525471029 EPS02689.1 WP_021137823.1 430 430 yes 1889058 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 640 658 yes 1889059 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1716, 1203564, 1203558, 1203560, 1203567, 1203563 Corynebacterium sp. KPL1857, Corynebacterium sp. KPL1817, Corynebacterium sp. KPL1821, Corynebacterium sp. KPL1860, Corynebacterium sp. KPL1856 Bacteria UP000017098, UP000017176, UP000017152, UP000017122, UP000017094 552773605, 550778708, 550763266, 550758467, 550747844, 550747830 ERS76733.1, ERS62188.1, ERS57568.1, ERS47317.1, ERS47306.1 WP_023021165.1 588 593 yes 1889060 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 517558926 WP_018729134.1 530 530 yes 1889061 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1286528 Neorickettsia helminthoeca str. Oregon Bacteria UP000023755 612502006 AHX11842.1 248 251 no 1889062 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1286528 Neorickettsia helminthoeca str. Oregon Bacteria UP000023755 612502005 AHX11841.1 314 317 no 1889063 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 992184, 992181, 992168, 992161, 992155, 992138, 992135, 992134, 992132, 992129, 992128 Yersinia pestis PY-103, Yersinia pestis PY-100, Yersinia pestis PY-72, Yersinia pestis PY-60, Yersinia pestis PY-53, Yersinia pestis PY-12, Yersinia pestis PY-09, Yersinia pestis PY-08, Yersinia pestis PY-06, Yersinia pestis PY-03, Yersinia pestis PY-02 Bacteria UP000004817, UP000005172, UP000002989, UP000003862, UP000003767, UP000005382, UP000005404, UP000003231, UP000003318, UP000005342, UP000003625 391723020, 391710050, 391635336, 391595464, 391566237, 391471512, 391455686, 391453688, 391441378, 391421816, 391421597 EIT52760.1, EIT41161.1, EIS74510.1, EIS39510.1, EIS14252.1, EIR29068.1, EIR14785.1, EIR12976.1, EIR01872.1, EIQ84471.1, EIQ84276.1 fig|992163.3.peg.4056, fig|992153.3.peg.4065, fig|992143.3.peg.3805, fig|992135.3.peg.3878, fig|992138.3.peg.4261, fig|992129.3.peg.4097, fig|992164.3.peg.4059, fig|992148.3.peg.4106, fig|992182.3.peg.3827, fig|992161.3.peg.4064, fig|992172.3.peg.3857, fig|992165.3.peg.4064, fig|992179.3.peg.3871, fig|992181.3.peg.3846, fig|992142.3.peg.3899, fig|992134.3.peg.4201, fig|992131.3.peg.3889, fig|992127.3.peg.4156, fig|992151.3.peg.3895, fig|992184.3.peg.3939, fig|992183.3.peg.4077, fig|992132.3.peg.4159, fig|992130.3.peg.4163, fig|992152.3.peg.4100, fig|992169.3.peg.3733, fig|992168.3.peg.3783, fig|992175.3.peg.3981, fig|992141.3.peg.4150, fig|992128.3.peg.4055, fig|992155.3.peg.4041, fig|992158.3.peg.3888 411 422 yes 1889064 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 173 Leptospira interrogans Bacteria UP000037872 487962363 WP_002035644.1 201 201 no 1889065 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992128 Yersinia pestis, Yersinia pestis PY-02 Bacteria UP000000815 UP000031825, UP000003625 488289823, 391421683 EIQ84352.1 WP_002361031.1 179 210 no 1889066 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 171, 1193045, 1193046, 1193048, 1049964, 1049941, 1240688, 1218583, 1218595, 1218584, 1049968, 1049945, 1193047, 1049946 Leptospira kirschneri str. 200801774, Leptospira kirschneri str. 200801925, Leptospira kirschneri str. 200803703, Leptospira kirschneri serovar Sokoine str. RM1, Leptospira kirschneri serovar Bim str. 1051, Leptospira kirschneri serovar Bim str. PUO 1247, Leptospira kirschneri str. MMD1493, Leptospira santarosai str. CBC613, Leptospira kirschneri str. JB, Leptospira kirschneri serovar Valbuzzi str. 200702274, Leptospira kirschneri serovar Grippotyphosa str. Moskva, Leptospira kirschneri str. 200802841, Leptospira kirschneri serovar Grippotyphosa str. RM52 Bacteria UP000012097, UP000012127, UP000012108, UP000012135, UP000012126, UP000011884, UP000011928, UP000011895, UP000011993, UP000001341, UP000001085, UP000006339, UP000006996 490893956, 464418508, 464409118, 464397629, 464210605, 464185294, 463350533, 463340752, 463340342, 463319544, 410751060, 410738628, 410001269, 400320437 EMO82388.1, EMO74491.1, EMO65434.1, EMN25333.1, EMN06368.1, EMK13882.1, EMK05003.1, EMK04656.1, EMJ85411.1, EKR08039.1, EKQ83362.1, EKO51883.1, EJO68307.1 WP_004755905.1 fig|1218583.3.peg.1871, fig|1193048.3.peg.1289, fig|1291205.3.peg.7932, fig|1049968.3.peg.2703, fig|1049941.3.peg.2483, fig|1049943.3.peg.1727, fig|1049946.3.peg.844, fig|1049969.3.peg.3783, fig|1193047.3.peg.2353, fig|1049944.3.peg.3856, fig|1240688.3.peg.3479, fig|1049945.3.peg.652, fig|1193046.3.peg.1290, fig|1218584.3.peg.4361, fig|1218595.3.peg.3318 440 494 yes 1889067 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 663, 1219076 Vibrio alginolyticus, Vibrio alginolyticus NBRC 15630 = ATCC 17749 Bacteria UP000066605, UP000016564 516432720, 541132049, 543452083 AGV17939.1 WP_017821775.1 640 646 yes 1889068 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298600 Vibrio owensii JCM 18905 Bacteria UP000026911 635162663 640 646 yes 1889069 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56946, 883078 Afipia broomeae, Afipia broomeae ATCC 49717 Bacteria UP000001096 492883681, 410888824 EKS36627.1 WP_006021750.1 fig|883078.3.peg.3148 634 643 yes 1889070 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 742823 Sutterella wadsworthensis 2_1_59BFAA Bacteria UP000005835 404657131 EKB30034.1 fig|742823.3.peg.2305 487 538 yes 1889071 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1421, 1285586 Lysinibacillus sphaericus, Lysinibacillus sphaericus OT4b.31 Bacteria UP000028424, UP000013911 499128827, 496194415 EON73656.1 WP_010857625.1 fig|1285586.5.peg.663 592 592 yes 1889072 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280670 Butyrivibrio sp. AD3002 Bacteria 551017944 WP_022762174.1 434 434 yes 1889073 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1501, 1262449 Clostridium pasteurianum, Clostridium pasteurianum DSM 525 Bacteria UP000030910 489541831, 736025254, 736019271, 662573805, 440219266 AJA53392.1, AJA49404.1, KER12877.1, ELP58480.1 WP_003446520.1 fig|1262449.3.peg.3021 433 433 yes 1889074 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 548, 1400141, 1400140, 1400142 Enterobacter aerogenes, Enterobacter aerogenes UCI 28, Enterobacter aerogenes UCI 27, Enterobacter aerogenes UCI 45 Bacteria UP000056714, UP000022456, UP000022265, UP000022519 695795373, 828903438, 822769392, 822747543, 822704832, 822702516, 771399562, 771062557, 733545857, 685441234, 578222873, 578218263, 578186905 AKK82390.1, KLF28358.1, KLF06798.1, KLE64605.1, KLE62313.1, KJP31364.1, KJM42253.1, KHM26398.1, KGB02063.1, EUL83044.1, EUL78448.1, EUL47202.1 WP_032709582.1 626 631 yes 1889075 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43263, 1333854 Pseudomonas alcaligenes, Pseudomonas alcaligenes OT 69 Bacteria UP000016069 544802604, 533210469 EQM68909.1 WP_021219772.1 627 627 yes 1889076 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144319 Herbaspirillum sp. CF444 Bacteria UP000007296 495158485, 398092950 EJL83346.1 WP_007883288.1 fig|1144319.3.peg.4314 640 641 yes 1889077 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1131277 alpha proteobacterium SCGC AB-629-F11 Bacteria 516677544 WP_018036260.1 172 172 no 1889078 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1229516 Mycobacterium marinum str. Europe Bacteria UP000014967 521813759 EPQ72973.1 546 548 yes 1889079 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444065 Escherichia coli, Escherichia coli 2-011-08_S1_C2 Bacteria UP000036210, UP000023885 693168243, 611116688 EZK16477.1 WP_032301119.1 626 631 yes 1889080 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 13769, 547559 Natrialba magadii, Natrialba magadii ATCC 43099 Archaea UP000001879 502761710, 289582248, 289531801 ADD06152.1 WP_012996694.1, YP_003480714.1 D3SYW0 D3SYW0_NATMM 10324291 462 503 yes 1889081 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1236971 Bacillus hemicellulosilyticus JCM 9152 Bacteria UP000018895 569809204 339 340 no 1889082 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1236971 Bacillus hemicellulosilyticus JCM 9152 Bacteria UP000018895 569809205 250 250 no 1889083 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 425 425 yes 1889084 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28223, 651182 Desulfobacula toluolica, Desulfobacula toluolica Tol2 Bacteria UP000007347 504772208, 405108633 WP_014959310.1 fig|651182.5.peg.4679 422 434 yes 1889085 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28116, 997886 Bacteroides ovatus, Bacteroides ovatus CL03T12C18 Bacteria UP000066017, UP000005506 490454953, 392670832 EIY64310.1 WP_004325766.1 fig|997886.3.peg.3046 565 565 yes 1889086 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644282 Desulfarculus baarsii DSM 2075 Bacteria UP000009047 301638261 ADK83583.1 fig|644282.4.peg.212 434 434 yes 1889087 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1194404 Pseudomonas syringae pv. actinidiae ICMP 18807 Bacteria UP000015729 519290099 EPN57849.1 506 506 yes 1889088 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 471, 1217690 Acinetobacter calcoaceticus, Acinetobacter sp. ANC 3811 Bacteria UP000032475, UP000014041 507068723, 500622004 EOQ62050.1 WP_016139502.1 fig|1217690.3.peg.2801 621 625 yes 1889089 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 596 605 yes 1889090 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 443143 Geobacter sp. M18 Bacteria UP000001442 505925756, 320124555 ADW12115.1 WP_015718984.1 fig|443143.3.peg.1714 436 436 yes 1889091 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 228, 722419 Pseudoalteromonas haloplanktis, Pseudoalteromonas haloplanktis ANT/505 Bacteria UP000004934 489050575, 332036218 EGI72691.1 WP_002960785.1 645 650 yes 1889092 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 385025 Cycloclasticus sp. P1 Bacteria UP000006282 504817891, 407255780 AFT66221.1 WP_015004993.1 fig|385025.3.peg.185 619 621 yes 1889093 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 837, 1211023 Porphyromonas gingivalis, Porphyromonas gingivalis SJD2 Bacteria UP000028798, UP000019115 564601947, 563396075 ETA27159.1 WP_023846862.1 587 587 yes 1889094 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 363754 Rhizobium tropici PRF 81 Bacteria UP000012429 478273337 ENN85283.1 fig|363754.4.peg.5366 564 572 yes 1889095 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626 653 yes 1889096 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644281 Methanocaldococcus sp. FS406-22 Archaea UP000002189 502746232, 288939559 ADC70314.1 WP_012981216.1 D3S650 D3S650_METSF 426 426 yes 1889097 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204042 Dickeya zeae Bacteria 515510603 WP_016943857.1 629 653 yes 1889098 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1116154 Escherichia coli P0302308.2 Bacteria UP000012248 477026711 END11557.1 fig|1116154.3.peg.3696 442 444 yes 1889099 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 1339288, 1339315, 1263046 Bacteroides fragilis, Bacteroides fragilis str. 3988 T1, Bacteroides fragilis str. 3988T(B)14, Bacteroides fragilis CAG:47 Bacteria, Environmental samples UP000036847, UP000022698, UP000020529, UP000018271 547947243, 595991153, 595982865, 524626712 EXY79989.1, EXY74081.1 WP_022348207.1 564 564 yes 1889100 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 513050, 515635 Dictyoglomus turgidum, Dictyoglomus turgidum DSM 6724 Bacteria UP000007719 UP000007719 501579679, 217968041, 217337140 ACK42933.1 WP_012584008.1, YP_002353547.1 5759167 fig|515635.3.peg.1710 414 417 no 1889101 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 152682 Sphingomonas melonis Bacteria 516605346 WP_017980369.1 627 635 yes 1889102 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 339862, 768710 Desulfosporosinus youngiae, Desulfosporosinus youngiae DSM 17734 Bacteria UP000005104 495060747, 374418498 EHQ90933.1 WP_007785579.1 430 432 yes 1889103 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 693743 Vibrio cholerae, Vibrio cholerae PS15 Bacteria UP000028983, UP000010427 487887596, 429226025 EKY32204.1 WP_001961062.1 fig|693743.7.peg.2195 639 645 yes 1889104 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28111, 665953 Bacteroides eggerthii, Bacteroides eggerthii 1_2_48FAA Bacteria UP000003246 490422845, 316906874 EFV28586.1 WP_004295072.1 561 562 yes 1889105 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543, 573, 562, 1444052, 1438681, 1444107, 1446601, 1328434, 1281069, 1281241, 1268989, 1268975, 1281191, 1281170, 1281109, 1281008, 1280994, 1280993, 1280976, 1169339, 1169382, 1181748, 1182657, 1169340 Klebsiella pneumoniae, Escherichia coli, Escherichia coli 1-250-04_S1_C1, Escherichia coli BIDMC 77, Escherichia coli 1-250-04_S1_C3, Escherichia coli O15:H18 str. K1516, Escherichia coli BWH 40, Escherichia coli HVH 136 (4-5970458), Escherichia coli UMEA 3323-1, Escherichia coli 907889, Escherichia coli 110957, Escherichia coli UMEA 3144-1, Escherichia coli KOEGE 77 (202a), Escherichia coli HVH 182 (4-0985554), Escherichia coli HVH 65 (4-2262045), Escherichia coli HVH 44 (4-2298570), Escherichia coli HVH 43 (4-2173468), Escherichia coli HVH 25 (4-5851939), Escherichia coli KTE20, Escherichia coli KTE125, Escherichia coli KTE202, Escherichia coli KTE50, Escherichia coli KTE21 Bacteria UP000036212, UP000036210, UP000027934, UP000027510, UP000024267, UP000023913, UP000021921, UP000017764, UP000017569, UP000017351, UP000017485, UP000016311, UP000016399, UP000016074, UP000016020, UP000016302, UP000016078, UP000016362, UP000014147, UP000010686, UP000010563, UP000010699, UP000010678 486158443, 839400908, 838802176, 838780749, 767824520, 729926746, 652005833, 635853929, 611091026, 607461839, 595607293, 595602737, 595598100, 575638211, 556123803, 554723473, 553627141, 553349276, 536012226, 535455730, 535188827, 534776775, 534713862, 534706066, 534631625, 508287480, 431577266, 431485296, 431321623, 430913044 KME77826.1, KLX84505.1, KLX63333.1, KJH04902.1, KHI18135.1, KDX25663.1, KDG34857.1, EZJ92152.1, EZB51545.1, AHM50939.1, AHM46384.1, AHM41750.1, ETY36983.1, ESP12349.1, ESK28766.1, ESD46564.1, ESA76487.1, ERB11486.1, EQV95882.1, EQT33155.1, EQP29338.1, EQO67413.1, EQO59759.1, EQN88276.1, EOU60428.1, ELI49911.1, ELH64959.1, ELG09224.1, ELC34179.1 WP_001522121.1 fig|1169382.3.peg.4404, fig|1169340.3.peg.5150, fig|1169339.3.peg.5183, fig|1182657.3.peg.1189, fig|1181748.3.peg.20 626 631 yes 1889106 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262868 Cryptobacterium sp. CAG:338 Environmental samples UP000018369 548076550, 524666669 WP_022378713.1 433 435 yes 1889107 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 752783 Escherichia coli, Escherichia coli KD1 Bacteria UP000036210, UP000003326 485833128, 388382712 EIL44558.1 WP_001445607.1 fig|752783.3.peg.4255 626 631 yes 1889108 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310931, 1311074, 1311069, 1311070, 1310932, 1310965, 1310929, 1310851, 1310709, 1310843, 1310839, 1310837, 1310852, 1310806, 1310831, 1310627, 1310584, 1310631, 1310629, 1310846, 1310559, 1310602, 1310568, 1310573, 1310572, 1311118, 1311066, 1311085, 1311065, 1311080, 1311082, 1310840, 1310954, 1311067, 1311076, 1311078, 1311079, 1311081, 1311083, 1311084, 1311086, 1311087, 1311122, 1311124, 1311134, 1311126, 1310717, 1311098, 1311071, 1311068, 1311073, 1311077, 1311113, 1311072, 1311075, 1311046, 1311045, 1311047, 1311048, 1311044, 1311036, 1311037, 1311035, 1311038, 1311040, 1311039, 1311041, 1311042, 1311043, 1311027, 1311028, 1311029, 1311033, 1311032, 1311031, 1311006, 1311007, 1311010, 1311009, 1311012, 1311013, 1310970, 1310972, 1310971, 1310985, 1310986, 1310988, 1310989, 1310991, 1310992, 1310984, 1310975, 1310976, 1310977, 1310978, 1310979, 1310980, 1310981, 1310982, 1310983, 1311003, 1311004, 1310990, 1310915, 1310964, 1310916, 1310917, 1310918, 1310919, 1310920, 1310923, 1310921, 1310924, 1310925, 1310926, 1310933, 1310930, 1310934, 1310935, 1310938, 1310939, 1310936, 1310940, 1310941, 1310942, 1310943, 1310949, 1310945, 1310944, 1310948, 1310951, 1310953, 1310961, 1310955, 1310956, 1310855, 1310857, 1310858, 1310860, 1310859, 1310863, 1310862, 1310861, 1310884, 1310875, 1310877, 1310879, 1310878, 1310880, 1310881, 1310866, 1310882, 1310869, 1310867, 1310868, 1310870, 1310872, 1310885, 1310886, 1310887, 1310888, 1310889, 1310890, 1310893, 1310865, 1310793, 1310792, 1310763, 1310757, 1310755, 1310794, 1310799, 1310785, 1310796, 1310775, 1310768, 1310765, 1310758, 1310774, 1310780, 1310777, 1310767, 1310746, 1310749, 1310741, 1310739, 1310708, 1310727, 1310735, 1310712, 1310754, 1310713, 1310743, 1310732, 1310731, 1310747, 1310751, 1310753, 1310810, 1310844, 1310848, 1310850, 1310836, 1310841, 1310838, 1310842, 1310811, 1310808, 1310805, 1310666, 1310698, 1310699, 1310672, 1310557, 1310555, 1310587, 1310561, 1310589, 1310582, 1310593, 1310560, 1310578, 1310562, 1310558, 1310600, 1310585, 1310567, 1310569, 1310574, 1310586, 1310556, 1310650, 1310610, 1310616, 1310646, 1310649, 1310617, 1310614, 1310620, 1310644, 1398979, 903922, 1168591, 992405 Acinetobacter baumannii, Acinetobacter baumannii 25691_7, Acinetobacter baumannii 26016_7, Acinetobacter baumannii 26016_2, Acinetobacter baumannii 26016_3, Acinetobacter baumannii 25691_8, Acinetobacter baumannii 25750_1, Acinetobacter baumannii 25691_5, Acinetobacter baumannii 24812_7, Acinetobacter baumannii 1288284, Acinetobacter baumannii 24860_9, Acinetobacter baumannii 24860_5, Acinetobacter baumannii 24860_3, Acinetobacter baumannii 24812_8, Acinetobacter baumannii 1505311, Acinetobacter baumannii 1042969-1197, Acinetobacter baumannii 1284800, Acinetobacter baumannii 23037, Acinetobacter baumannii 15827, Acinetobacter baumannii 135867, Acinetobacter baumannii 24812_2, Acinetobacter baumannii 987421, Acinetobacter baumannii 96512, Acinetobacter baumannii 916567, Acinetobacter baumannii 18689, Acinetobacter baumannii 1032359, Acinetobacter baumannii 25442_1, Acinetobacter baumannii 44839_9, Acinetobacter baumannii 44298_8, Acinetobacter baumannii 44839_8, Acinetobacter baumannii 44298_3, Acinetobacter baumannii 44298_5, Acinetobacter baumannii 24860_6, Acinetobacter baumannii 24975_10, Acinetobacter baumannii 44839_10, Acinetobacter baumannii 26016_9, Acinetobacter baumannii 44298_1, Acinetobacter baumannii 44298_2, Acinetobacter baumannii 44298_4, Acinetobacter baumannii 44298_6, Acinetobacter baumannii 44298_7, Acinetobacter baumannii 44298_9, Acinetobacter baumannii 44298_10, Acinetobacter baumannii 25442_5, Acinetobacter baumannii 25442_7, Acinetobacter baumannii 42057_2, Acinetobacter baumannii 25442_9, Acinetobacter baumannii 1457504, Acinetobacter baumannii 16553_1, Acinetobacter baumannii 26016_4, Acinetobacter baumannii 26016_1, Acinetobacter baumannii 26016_6, Acinetobacter baumannii 26016_10, Acinetobacter baumannii 25569_6, Acinetobacter baumannii 26016_5, Acinetobacter baumannii 26016_8, Acinetobacter baumannii 25878_2, Acinetobacter baumannii 25878_1, Acinetobacter baumannii 25878_3, Acinetobacter baumannii 43557_1, Acinetobacter baumannii 44362_10, Acinetobacter baumannii 44362_2, Acinetobacter baumannii 44362_3, Acinetobacter baumannii 44362_1, Acinetobacter baumannii 44362_4, Acinetobacter baumannii 44362_6, Acinetobacter baumannii 44362_5, Acinetobacter baumannii 44362_7, Acinetobacter baumannii 44362_8, Acinetobacter baumannii 44362_9, Acinetobacter baumannii 44437_3, Acinetobacter baumannii 44437_4, Acinetobacter baumannii 44437_5, Acinetobacter baumannii 44437_9, Acinetobacter baumannii 44437_8, Acinetobacter baumannii 44437_7, Acinetobacter baumannii 25681_2, Acinetobacter baumannii 25681_3, Acinetobacter baumannii 25681_6, Acinetobacter baumannii 25681_5, Acinetobacter baumannii 25681_8, Acinetobacter baumannii 25681_9, Acinetobacter baumannii 25750_6, Acinetobacter baumannii 25750_8, Acinetobacter baumannii 25750_7, Acinetobacter baumannii 44327_1, Acinetobacter baumannii 44327_2, Acinetobacter baumannii 44327_4, Acinetobacter baumannii 44327_5, Acinetobacter baumannii 44327_7, Acinetobacter baumannii 44327_8, Acinetobacter baumannii 44467_10, Acinetobacter baumannii 44467_1, Acinetobacter baumannii 44467_2, Acinetobacter baumannii 44467_3, Acinetobacter baumannii 44467_4, Acinetobacter baumannii 44467_5, Acinetobacter baumannii 44467_6, Acinetobacter baumannii 44467_7, Acinetobacter baumannii 44467_8, Acinetobacter baumannii 44467_9, Acinetobacter baumannii 44857_9, Acinetobacter baumannii 44857_10, Acinetobacter baumannii 44327_6, Acinetobacter baumannii 25766_1, Acinetobacter baumannii 25561_10, Acinetobacter baumannii 25766_2, Acinetobacter baumannii 25766_3, Acinetobacter baumannii 25766_4, Acinetobacter baumannii 25766_5, Acinetobacter baumannii 25766_6, Acinetobacter baumannii 25766_9, Acinetobacter baumannii 25766_7, Acinetobacter baumannii 25766_10, Acinetobacter baumannii 25691_1, Acinetobacter baumannii 25691_2, Acinetobacter baumannii 25691_9, Acinetobacter baumannii 25691_6, Acinetobacter baumannii 25691_10, Acinetobacter baumannii 25935_1, Acinetobacter baumannii 25935_4, Acinetobacter baumannii 25935_5, Acinetobacter baumannii 25935_2, Acinetobacter baumannii 25935_6, Acinetobacter baumannii 25935_7, Acinetobacter baumannii 25935_8, Acinetobacter baumannii 25935_9, Acinetobacter baumannii 24975_5, Acinetobacter baumannii 24975_1, Acinetobacter baumannii 25935_10, Acinetobacter baumannii 24975_4, Acinetobacter baumannii 24975_7, Acinetobacter baumannii 24975_9, Acinetobacter baumannii 25561_7, Acinetobacter baumannii 25561_1, Acinetobacter baumannii 25561_2, Acinetobacter baumannii 24845_1, Acinetobacter baumannii 24845_3, Acinetobacter baumannii 24845_4, Acinetobacter baumannii 24845_6, Acinetobacter baumannii 24845_5, Acinetobacter baumannii 24845_9, Acinetobacter baumannii 24845_8, Acinetobacter baumannii 24845_7, Acinetobacter baumannii 25253_10, Acinetobacter baumannii 25253_1, Acinetobacter baumannii 25253_3, Acinetobacter baumannii 25253_5, Acinetobacter baumannii 25253_4, Acinetobacter baumannii 25253_6, Acinetobacter baumannii 25253_7, Acinetobacter baumannii 25307_2, Acinetobacter baumannii 25253_8, Acinetobacter baumannii 25307_5, Acinetobacter baumannii 25307_3, Acinetobacter baumannii 25307_4, Acinetobacter baumannii 25307_6, Acinetobacter baumannii 25307_8, Acinetobacter baumannii 44895_1, Acinetobacter baumannii 44895_2, Acinetobacter baumannii 44895_3, Acinetobacter baumannii 44895_4, Acinetobacter baumannii 44895_5, Acinetobacter baumannii 44895_6, Acinetobacter baumannii 44895_9, Acinetobacter baumannii 25307_1, Acinetobacter baumannii 98826, Acinetobacter baumannii 981176, Acinetobacter baumannii 213697, Acinetobacter baumannii 755829, Acinetobacter baumannii 628418, Acinetobacter baumannii 303002, Acinetobacter baumannii 1494580, Acinetobacter baumannii 466215, Acinetobacter baumannii 1406182, Acinetobacter baumannii 1392509, Acinetobacter baumannii 1397513, Acinetobacter baumannii 1294222, Acinetobacter baumannii 1266220, Acinetobacter baumannii 1232509, Acinetobacter baumannii 1117819, Acinetobacter baumannii 1262761-97, Acinetobacter baumannii 1237202, Acinetobacter baumannii 1287985, Acinetobacter baumannii 10519, Acinetobacter baumannii 73736, Acinetobacter baumannii 1045092, Acinetobacter baumannii 923118, Acinetobacter baumannii 836190, Acinetobacter baumannii 737393, Acinetobacter baumannii 655555, Acinetobacter baumannii 2887, Acinetobacter baumannii 1471012, Acinetobacter baumannii 1264936, Acinetobacter baumannii 1271651, Acinetobacter baumannii 1178044, Acinetobacter baumannii 1095464, Acinetobacter baumannii 1022959, Acinetobacter baumannii 1296252, Acinetobacter baumannii 7893, Acinetobacter baumannii 24860_10, Acinetobacter baumannii 24812_4, Acinetobacter baumannii 24812_6, Acinetobacter baumannii 24860_2, Acinetobacter baumannii 24860_7, Acinetobacter baumannii 24860_4, Acinetobacter baumannii 24860_8, Acinetobacter baumannii 458282, Acinetobacter baumannii 470922, Acinetobacter baumannii 1426993, Acinetobacter baumannii 1552818, Acinetobacter baumannii 1593273, Acinetobacter baumannii 1575710, Acinetobacter baumannii 554515, Acinetobacter baumannii 959073, Acinetobacter baumannii 993520, Acinetobacter baumannii 947299, Acinetobacter baumannii 942133, Acinetobacter baumannii 929679-2095, Acinetobacter baumannii 662545-1347, Acinetobacter baumannii 796380-2102, Acinetobacter baumannii 564012, Acinetobacter baumannii 34001, Acinetobacter baumannii 472237-1196, Acinetobacter baumannii 136706, Acinetobacter baumannii 1289546, Acinetobacter baumannii 1051830, Acinetobacter baumannii 1046674, Acinetobacter baumannii 1043903, Acinetobacter baumannii 1042969-1265, Acinetobacter baumannii 1031433, Acinetobacter baumannii 17534, Acinetobacter baumannii 724909, Acinetobacter baumannii 647609, Acinetobacter baumannii 400834, Acinetobacter baumannii 1462234, Acinetobacter baumannii 1465485, Acinetobacter baumannii 1406750, Acinetobacter baumannii 1397084, Acinetobacter baumannii 1294217, Acinetobacter baumannii 1159076, Acinetobacter baumannii UH7007, Acinetobacter baumannii Naval-2, Acinetobacter baumannii Ab44444, Acinetobacter baumannii ABNIH4 Bacteria UP000028632, UP000027340, UP000027346, UP000027280, UP000027018, UP000027105, UP000027147, UP000027089, UP000027353, UP000027130, UP000027003, UP000027047, UP000027204, UP000027171, UP000027351, UP000027165, UP000027056, UP000027156, UP000027254, UP000027114, UP000027072, UP000027296, UP000027024, UP000027322, UP000027316, UP000027054, UP000027134, UP000027257, UP000027012, UP000027232, UP000027122, UP000027157, UP000023854, UP000024111, UP000024061, UP000024211, UP000024224, UP000023884, UP000023987, UP000024081, UP000024231, UP000024080, UP000024102, UP000024091, UP000024104, UP000023818, UP000024205, UP000020011, UP000022491, UP000023542, UP000020477, UP000019850, UP000020010, UP000020689, UP000023553, UP000023554, UP000021523, UP000021520, UP000023505, UP000021227, UP000023396, UP000023233, UP000021158, UP000022839, UP000022958, UP000021894, UP000021671, UP000020905, UP000021570, UP000023017, UP000021845, UP000022807, UP000022338, UP000021149, UP000023463, UP000021381, UP000023097, UP000022119, UP000019806, UP000022547, UP000020654, UP000023136, UP000023058, UP000022752, UP000023468, UP000022531, UP000022719, UP000021583, UP000021654, UP000020932, UP000019867, UP000022505, UP000021932, UP000020841, UP000020507, UP000022987, UP000020237, UP000022742, UP000021393, UP000022736, UP000022440, UP000022441, UP000020096, UP000022074, UP000022684, UP000021565, UP000023245, UP000023365, UP000021749, UP000022588, UP000022488, UP000022117, UP000023057, UP000020819, UP000021422, UP000021547, UP000021160, UP000020399, UP000022686, UP000023385, UP000022863, UP000019808, UP000020064, UP000021751, UP000022025, UP000022650, UP000020151, UP000021082, UP000023528, UP000019866, UP000022073, UP000021036, UP000022816, UP000022035, UP000022343, UP000021511, UP000020570, UP000022086, UP000020753, UP000022783, UP000023423, UP000020656, UP000020992, UP000020327, UP000020115, UP000020044, UP000022931, UP000020983, UP000023240, UP000023294, UP000023063, UP000020201, UP000021959, UP000020662, UP000020200, UP000022849, UP000023364, UP000021764, UP000022367, UP000023065, UP000022439, UP000023391, UP000022753, UP000021770, UP000020596, UP000023309, UP000020715, UP000023533, UP000019924, UP000021442, UP000022410, UP000021313, UP000020175, UP000021062, UP000020081, UP000020931, UP000021966, UP000021166, UP000020986, UP000022395, UP000020962, UP000022039, UP000021454, UP000021965, UP000020198, UP000020347, UP000021254, UP000023455, UP000021639, UP000022960, UP000020809, UP000021264, UP000021949, UP000021336, UP000020247, UP000022170, UP000021563, UP000020832, UP000020251, UP000020286, UP000021737, UP000021756, UP000020982, UP000021922, UP000020760, UP000021962, UP000020847, UP000020091, UP000022562, UP000020000, UP000020430, UP000022678, UP000020517, UP000020120, UP000022704, UP000022010, UP000023353, UP000023425, UP000020929, UP000023132, UP000021365, UP000020249, UP000021920, UP000021273, UP000022248, UP000021592, UP000021185, UP000021635, UP000021559, UP000022321, UP000021265, UP000020980, UP000020892, UP000022051, UP000021711, UP000020865, UP000020629, UP000020162, UP000022221, UP000023408, UP000022057, UP000018966, UP000002843, UP000005398, UP000006169 446995596, 763950600, 741327701, 741322419, 741315776, 630650069, 630618025, 630610741, 630607779, 630600835, 630592718, 630582979, 630577532, 630566805, 630561762, 630556369, 630551386, 630547615, 630536166, 630523979, 630501746, 630498409, 630478733, 630438030, 630425860, 630424449, 630416521, 630413064, 630405899, 629045969, 629019206, 629006425, 628996647, 628996343, 628989084, 628988101, 611006565, 611000234, 610998534, 610994129, 610989785, 610986280, 610980699, 610978562, 610974701, 610968833, 610964774, 610957368, 610949039, 610944614, 610940802, 604703257, 601431709, 601390455, 601376390, 601374536, 601360956, 601356615, 601352859, 601345977, 598595066, 598581906, 598574663, 598565016, 598564090, 598553498, 598552183, 598552104, 598541331, 598539432, 598537976, 598531071, 598525744, 598524580, 598521514, 598519112, 598515151, 598510240, 598506762, 598502289, 595331198, 595326830, 595322815, 595320643, 595314509, 595310045, 595309813, 595300670, 595298799, 595291892, 595284742, 595282106, 595279238, 595271774, 595268502, 595266828, 595258257, 595254041, 595253559, 595243236, 595241216, 595240641, 595230230, 595229512, 595228201, 595226738, 595222560, 595215598, 595213723, 595208068, 595203382, 595199684, 595195668, 595191803, 595185929, 595185639, 595179260, 595174273, 595170272, 595167404, 595160010, 595159480, 595153404, 595149150, 595147175, 595141908, 595138249, 595131652, 595127894, 595125491, 595121797, 595117793, 595111873, 595107688, 595101717, 595095500, 595094308, 595089279, 595085425, 595082943, 594002284, 593996393, 593993883, 593990815, 593985909, 593983076, 593976094, 593975151, 593967004, 593964973, 593959983, 593954978, 593953922, 593948246, 593945266, 593941242, 593935965, 593926779, 593926274, 593924530, 593917156, 593912616, 593873583, 593870054, 593865395, 593861792, 593858390, 593850594, 593842362, 593806158, 593675529, 593672318, 593661743, 593636170, 593632295, 593626083, 593622343, 593596247, 593577779, 593573244, 593569356, 593560424, 593541836, 593526864, 593519531, 593516144, 593512057, 589577029, 589569154, 589568837, 589564969, 589562298, 589551701, 589544652, 589541024, 589511887, 589478029, 589460503, 589438405, 589422097, 589415755, 589410301, 589390642, 589225853, 589219013, 589218904, 589214607, 589205972, 589203329, 589200302, 589191577, 589178365, 589175180, 589153822, 588692825, 588244675, 588233454, 588172499, 588121169, 588107274, 588104726, 588100550, 588097023, 588091759, 588080936, 588068187, 588058156, 588050512, 588038068, 588028108, 588010622, 588004684, 588000133, 587990542, 587961701, 587957245, 587935958, 587926128, 587906349, 587874744, 587869216, 587828869, 587822618, 587808367, 587787714, 571716088, 410395017, 404673001, 342234557 KJC98365.1, KHV47783.1, KHV42602.1, KHV37079.1, KCZ41984.1, KCZ14312.1, KCZ08146.1, KCZ05362.1, KCZ00960.1, KCY94870.1, KCY86472.1, KCY81565.1, KCY71888.1, KCY67236.1, KCY62186.1, KCY57460.1, KCY53850.1, KCY43140.1, KCY31623.1, KCY10654.1, KCY07584.1, KCX89855.1, KCX53851.1, KCX42993.1, KCX41617.1, KCX34043.1, KCX30771.1, KCX24296.1, KCW42655.1, KCW17642.1, KCW05356.1, KCV95945.1, KCV95647.1, KCV88828.1, KCV87867.1, EZJ11586.1, EZJ05520.1, EZJ03867.1, EZI99629.1, EZI95515.1, EZI92095.1, EZI86814.1, EZI84735.1, EZI80977.1, EZI75399.1, EZI71517.1, EZI64361.1, EZI56270.1, EZI52036.1, EZI48358.1, EYU48213.1, EYS79481.1, EYS39590.1, EYS26049.1, EYS24240.1, EYS11318.1, EYS07119.1, EYS03465.1, EYR96952.1, EYD42168.1, EYD30099.1, EYD23498.1, EYD14368.1, EYD13627.1, EYD03613.1, EYD02431.1, EYD02365.1, EYC92557.1, EYC90795.1, EYC89559.1, EYC83224.1, EYC78171.1, EYC77178.1, EYC74267.1, EYC71981.1, EYC68168.1, EYC63661.1, EYC60368.1, EYC56087.1, EXX48202.1, EXX43970.1, EXX39999.1, EXX37856.1, EXX31998.1, EXX27620.1, EXX27392.1, EXX18624.1, EXX16788.1, EXX10156.1, EXX03244.1, EXX00695.1, EXW97998.1, EXW90806.1, EXW87653.1, EXW86259.1, EXW78215.1, EXW74293.1, EXW73873.1, EXW64202.1, EXW62270.1, EXW61737.1, EXW51719.1, EXW51032.1, EXW49806.1, EXW48562.1, EXW44506.1, EXW37847.1, EXW36056.1, EXW30767.1, EXW26311.1, EXW22747.1, EXW18844.1, EXW15088.1, EXW09466.1, EXW09180.1, EXW02983.1, EXV98234.1, EXV94380.1, EXV91574.1, EXV84456.1, EXV83938.1, EXV78069.1, EXV73963.1, EXV72059.1, EXV67017.1, EXV63428.1, EXV57203.1, EXV53551.1, EXV51218.1, EXV47635.1, EXV43791.1, EXV38173.1, EXV34093.1, EXV28496.1, EXV22557.1, EXV21395.1, EXV17280.1, EXV13525.1, EXV11225.1, EXU54204.1, EXU48416.1, EXU45964.1, EXU42968.1, EXU38183.1, EXU35414.1, EXU28652.1, EXU27729.1, EXU19961.1, EXU17978.1, EXU13172.1, EXU08229.1, EXU07190.1, EXU01733.1, EXT98815.1, EXT94944.1, EXT90173.1, EXT81689.1, EXT81189.1, EXT79545.1, EXT72416.1, EXT67947.1, EXT30391.1, EXT26949.1, EXT22470.1, EXT18962.1, EXT15624.1, EXT08079.1, EXT00233.1, EXS65509.1, EXS54217.1, EXS51181.1, EXS41262.1, EXS16641.1, EXS12847.1, EXS06980.1, EXS03470.1, EXR78298.1, EXR60585.1, EXR56157.1, EXR52400.1, EXR43918.1, EXR25984.1, EXR11505.1, EXR04588.1, EXR01272.1, EXQ97317.1, EXI55575.1, EXI47891.1, EXI47581.1, EXI43885.1, EXI41269.1, EXI30931.1, EXI24105.1, EXI20605.1, EXH92317.1, EXH59569.1, EXH42683.1, EXH21653.1, EXH06213.1, EXH00082.1, EXG94719.1, EXG75433.1, EXG69339.1, EXG62813.1, EXG62706.1, EXG58480.1, EXG50436.1, EXG47840.1, EXG44858.1, EXG36547.1, EXG23676.1, EXG20531.1, EXF99713.1, EXF65291.1, EXF16438.1, EXF05515.1, EXE46500.1, EXD99316.1, EXD85865.1, EXD83605.1, EXD79786.1, EXD76476.1, EXD71645.1, EXD61374.1, EXD49274.1, EXD39555.1, EXD32105.1, EXD20434.1, EXD10769.1, EXC94016.1, EXC88251.1, EXC83834.1, EXC74782.1, EXC46951.1, EXC42813.1, EXC22813.1, EXC13374.1, EXB94423.1, EXB63876.1, EXB58540.1, EXB19803.1, EXB13703.1, EXB00440.1, EXA80698.1, ETR04901.1, EKP47335.1, EKB40805.1, EGT99204.1 WP_001072852.1 fig|1221255.3.peg.2077, fig|992405.3.peg.3308, fig|1200351.3.peg.289, fig|903922.3.peg.3525, fig|1200350.3.peg.284, fig|933263.3.peg.1029, fig|1168591.3.peg.3293 621 625 yes 1889109 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1260, 866779 Finegoldia magna, Finegoldia magna SY403409CC001050417 Bacteria UP000003483 488929807, 341592333 EGS35219.1 WP_002840882.1 fig|866779.4.peg.204 433 433 yes 1889110 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 596155 Salmonella enterica, Salmonella enterica subsp. enterica serovar Infantis str. SARB27 Bacteria UP000054489, UP000004564 446030578, 353073914 EHB39678.1 WP_000108433.1 fig|596155.6.peg.4270 626 631 yes 1889111 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1454606, 1454603, 1173877, 1410933, 1079473, 766761, 763921, 763920, 749947, 749948, 749952 Salmonella enterica, Salmonella enterica subsp. enterica serovar Montevideo str. USDA-ARS-USMARC-1921, Salmonella enterica subsp. enterica serovar Montevideo str. USDA-ARS-USMARC-1903, Salmonella enterica subsp. enterica serovar Montevideo str. FVM_628064, Salmonella enterica subsp. enterica serovar Muenster str. CFSAN004344, Salmonella enterica subsp. enterica serovar Montevideo str. 8387, Salmonella enterica subsp. enterica serovar Montevideo str. 4441 H, Salmonella enterica subsp. enterica serovar Montevideo str. 42N, Salmonella enterica subsp. enterica serovar Montevideo str. 29N, Salmonella enterica subsp. enterica serovar Montevideo str. SARB30, Salmonella enterica subsp. enterica serovar Montevideo str. LQC 10, Salmonella enterica subsp. enterica serovar Montevideo str. SARB31 Bacteria UP000054489, UP000033051, UP000032211, UP000027430, UP000018555, UP000017264, UP000005547, UP000003435, UP000003404, UP000004590, UP000003700, UP000004212 446030579, 808195702, 764053397, 646665961, 564536934, 554199265, 363578524, 363574858, 363561366, 363560492, 363549353, 363548551 AKD14584.1, AJQ72169.1, KDQ89258.1, ETC33918.1, ESG37736.1, EHL62330.1, EHL58719.1, EHL45487.1, EHL44636.1, EHL33708.1, EHL32920.1 WP_000108434.1 fig|749952.3.peg.4556, fig|763921.3.peg.2188, fig|763920.3.peg.3613, fig|749948.3.peg.4250, fig|766761.3.peg.769, fig|749947.3.peg.4213 626 631 yes 1889112 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 59201, 859199, 882868, 882862, 882860, 984242, 984241, 763922, 984240, 882869, 882867, 882866, 882865, 882864, 882863, 871593, 871592, 871591, 871590, 871589, 871588, 871587, 871586, 859198, 858318, 858317, 858316, 858315, 858314, 858313, 789332, 766762, 763919, 749951, 749950, 749949, 745021, 745020, 745019, 745018, 745017, 745015 Salmonella enterica, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Montevideo str. 507440-20, Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008286, Salmonella enterica subsp. enterica serovar Montevideo str. CT_02035327, Salmonella enterica subsp. enterica serovar Montevideo str. CT_02035321, Salmonella enterica subsp. enterica serovar Montevideo str. CT_02035320, Salmonella enterica subsp. enterica serovar Montevideo str. CT_02035318, Salmonella enterica subsp. enterica serovar Montevideo str. 80959-06, Salmonella enterica subsp. enterica serovar Montevideo str. CT_02035278, Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008287, Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008285, Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008284, Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008283, Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008282, Salmonella enterica subsp. enterica serovar Montevideo str. IA_2009159199, Salmonella enterica subsp. enterica serovar Montevideo str. 315731156, Salmonella enterica subsp. enterica serovar Montevideo str. 2009085258, Salmonella enterica subsp. enterica serovar Montevideo str. 2009083312, Salmonella enterica subsp. enterica serovar Montevideo str. MB111609-0052, Salmonella enterica subsp. enterica serovar Montevideo str. MB110209-0055, Salmonella enterica subsp. enterica serovar Montevideo str. MB102109-0047, Salmonella enterica subsp. enterica serovar Montevideo str. MB101509-0077, Salmonella enterica subsp. enterica serovar Montevideo str. 556152, Salmonella enterica subsp. enterica serovar Montevideo str. 609460, Salmonella enterica subsp. enterica serovar Montevideo str. 556150-1, Salmonella enterica subsp. enterica serovar Montevideo str. 609458-1, Salmonella enterica subsp. enterica serovar Montevideo str. 446600, Salmonella enterica subsp. enterica serovar Montevideo str. 413180, Salmonella enterica subsp. enterica serovar Montevideo str. 366867, Salmonella enterica subsp. enterica serovar Montevideo str. 414877, Salmonella enterica subsp. enterica serovar Montevideo str. MD_MDA09249507, Salmonella enterica subsp. enterica serovar Montevideo str. 81038-01, Salmonella enterica subsp. enterica serovar Montevideo str. 19N, Salmonella enterica subsp. enterica serovar Montevideo str. CASC_09SCPH15965, Salmonella enterica subsp. enterica serovar Montevideo str. OH_2009072675, Salmonella enterica subsp. enterica serovar Montevideo str. NC_MB110209-0054, Salmonella enterica subsp. enterica serovar Montevideo str. 515920-2, Salmonella enterica subsp. enterica serovar Montevideo str. 515920-1, Salmonella enterica subsp. enterica serovar Montevideo str. 495297-4, Salmonella enterica subsp. enterica serovar Montevideo str. 495297-3, Salmonella enterica subsp. enterica serovar Montevideo str. 495297-1, Salmonella enterica subsp. enterica serovar Montevideo str. 315996572 Bacteria UP000054489, UP000033855, UP000004373, UP000005073, UP000005333, UP000004287, UP000004428, UP000003347, UP000002974, UP000004437, UP000003102, UP000005696, UP000005542, UP000005281, UP000004124, UP000003470, UP000005720, UP000005789, UP000003427, UP000005028, UP000005793, UP000004164, UP000006244, UP000004357, UP000006451, UP000005151, UP000006434, UP000003236, UP000004618, UP000005935, UP000003514, UP000003398, UP000003190, UP000006191, UP000004122, UP000004868, UP000004192, UP000006448, UP000006192, UP000005312, UP000005575, UP000004432, UP000006189 446030577, 703998429, 605514748, 372205458, 366076973, 366075960, 366069028, 366065615, 366064099, 366054525, 323268447, 323263940, 323262054, 323256923, 323252583, 323249700, 323242592, 323240075, 323235761, 323230979, 323225733, 323221340, 323218051, 323211611, 323202175, 323200686, 323193394, 322688126, 322679359, 322679201, 322670975, 322669746, 322665563, 322657301, 322655902, 322650798, 322646800, 322635206, 322631493, 322626658, 322625944, 322617284, 322616273 KGR31742.1, AHW11984.1, EHP18969.1, EHN41001.1, EHN40003.1, EHN33157.1, EHN29802.1, EHN28304.1, EHN18876.1, EGA51917.1, EGA47454.1, EGA45618.1, EGA40635.1, EGA36424.1, EGA33607.1, EGA26614.1, EGA24121.1, EGA19843.1, EGA15096.1, EGA09954.1, EGA05762.1, EGA02764.1, EFZ96448.1, EFZ87231.1, EFZ85759.1, EFZ78604.1, EFY84090.1, EFY75406.1, EFY75254.1, EFY67107.1, EFY65891.1, EFY61748.1, EFY53580.1, EFY52203.1, EFY47191.1, EFY43304.1, EFY31924.1, EFY28250.1, EFY23460.1, EFY22759.1, EFY14186.1, EFY13183.1 WP_000108432.1 fig|871593.3.peg.3300, fig|763919.3.peg.4438, fig|745018.3.peg.193, fig|749950.3.peg.1819, fig|858317.4.peg.2881, fig|882868.3.peg.3112, fig|745020.4.peg.3609, fig|789332.3.peg.713, fig|984242.3.peg.3082, fig|858315.3.peg.4547, fig|871586.3.peg.2682, fig|766762.3.peg.456, fig|882869.3.peg.4513, fig|984241.3.peg.13, fig|745019.4.peg.4037, fig|745017.4.peg.4580, fig|882863.4.peg.570, fig|745021.4.peg.4331, fig|763922.3.peg.612, fig|882860.3.peg.321, fig|871587.3.peg.623, fig|745015.3.peg.1049, fig|749951.3.peg.1270, fig|882867.3.peg.4579, fig|871590.3.peg.1597, fig|858314.3.peg.96, fig|749949.3.peg.1264, fig|871589.3.peg.2425, fig|882864.4.peg.2225, fig|984240.3.peg.4646, fig|871592.3.peg.1304, fig|859198.4.peg.3063, fig|871588.3.peg.2137, fig|871591.3.peg.1245, fig|882866.3.peg.1888, fig|882865.3.peg.2508, fig|859199.4.peg.363, fig|882862.3.peg.4128, fig|858318.3.peg.18, fig|858313.3.peg.4063 626 631 yes 1889113 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 219571, 1163408 Rhodanobacter fulvus, Rhodanobacter fulvus Jip2 Bacteria UP000004210 494141842, 388432302 EIL89316.1 WP_007081592.1 fig|1163408.3.peg.2010 607 610 yes 1889114 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314290 Vibrio sp. MED222 Bacteria UP000004451 497533974, 85833939 EAQ52101.1 WP_009848172.1 fig|314290.3.peg.3372 640 649 yes 1889115 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 883166 Staphylococcus simulans ACS-120-V-Sch1 Bacteria UP000001329 410875150 EKS23077.1 fig|883166.5.peg.2420 269 269 no 1889116 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410681, 1116472 Methyloglobulus morosus, Methylococcaceae bacterium KoM1 Bacteria UP000017842 558564288, 557869462 ESS72491.1 WP_023494493.1 624 626 yes 1889117 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 217159, 536227 Clostridium carboxidivorans, Clostridium carboxidivorans P7 Bacteria UP000002830 494120406, 848259093, 296050130, 255512024 AKN29521.1, EFG89554.1, EET88306.1 WP_007060184.1 fig|536227.3.peg.1268 436 437 yes 1889118 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1505232, 1313304 Chitinivibrio alkaliphilus, candidate division TG3 bacterium ACht1 Bacteria UP000017148 550655143, 550267481 ERP39160.1 WP_022635873.1 427 427 yes 1889119 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1234603 Candidatus Moranella endobia PCVAL Bacteria UP000013002 478755741 AGJ61300.1 fig|1234603.3.peg.286 362 362 yes 1889120 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 964, 757424 Herbaspirillum seropedicae, Herbaspirillum seropedicae SmR1 Bacteria UP000036083, UP000000329 502997495, 852455075, 300072553 AKN64135.1, ADJ61952.1 WP_013232471.1 fig|757424.7.peg.436 636 637 yes 1889121 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 911243, 1114970 Pseudomonas sp. CFII68, Pseudomonas fluorescens F113 Bacteria UP000014868, UP000005437 504102285, 515428406, 359758490 EPJ76487.1, AEV60569.1 WP_014336271.1 fig|1114970.3.peg.546 628 629 yes 1889122 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 180454 Anopheles gambiae str. PEST Invertebrates 158284399, 157021122 EAU78027.2 XP_001230318.2 75 90 no 1889123 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 397865, 880074 Barnesiella viscericola, Barnesiella viscericola DSM 18177 Bacteria UP000018901 644091100, 570740785 AHF11545.1 WP_025277287.1 567 567 yes 1889124 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717, 698965 Corynebacterium diphtheriae, Corynebacterium diphtheriae CDCE 8392 Bacteria UP000033584, UP000007156 504072230, 372104967 AEX71029.1 WP_014306224.1 fig|698965.3.peg.31 592 599 yes 1889125 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285562, 1120227 Streptomyces coelicoflavus, Streptomyces coelicoflavus ZG0656 Bacteria UP000003638 494630938, 371551509 EHN78798.1 WP_007388882.1 fig|1120227.3.peg.1573 600 613 yes 1889126 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1339264 Pseudomonas aeruginosa, Pseudomonas aeruginosa ID4365 Bacteria UP000065817, UP000024798 759853439, 618780434 KAJ17145.1 WP_043544796.1 627 627 yes 1889127 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28124, 553175 Porphyromonas endodontalis, Porphyromonas endodontalis ATCC 35406 Bacteria UP000004295 490464395, 229316143 EEN82070.1 WP_004334946.1 fig|553175.3.peg.1597, fig|553198.3.peg.223 592 592 yes 1889128 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 193, 137722 Azospirillum lipoferum, Azospirillum sp. B510 Bacteria UP000002040 502738171, 288909678 WP_012973155.1 fig|137722.3.peg.583 573 575 yes 1889129 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 642, 29489 Aeromonas enteropelogenes Bacteria UP000036234 516374611, 848286760 KMK97096.1 WP_017764644.1 662 680 yes 1889130 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 519084627 WP_020240502.1 626 631 yes 1889131 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 396005 bacterium QM42 Bacteria 519051979 WP_020207854.1 636 638 yes 1889132 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28026, 547043, 1454376, 1263060 Bifidobacterium pseudocatenulatum, Bifidobacterium pseudocatenulatum DSM 20438, Bifidobacterium pseudocatenulatum IPLA36007, Bifidobacterium pseudocatenulatum CAG:263 Bacteria, Environmental samples UP000028994, UP000027914, UP000018036 547837443, 672980571, 656093692, 781879306, 524474473 KFI75880.1, KEF28310.1 WP_022245189.1 628 879 yes 1889133 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 634, 349968 Yersinia bercovieri, Yersinia bercovieri ATCC 43970 Bacteria UP000047825, UP000010319 491419777, 238713542 EEQ05573.1 WP_005277576.1 fig|349968.5.peg.3157 648 671 yes 1889134 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1182713, 1182654 Escherichia coli, Escherichia coli KTE126, Escherichia coli KTE47 Bacteria UP000036210, UP000014170, UP000010679 486208237, 508462110, 431080045 EOW31732.1, ELD86857.1 WP_001553808.1 fig|1182713.3.peg.4787, fig|1182654.3.peg.4781 626 631 yes 1889135 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 866777 Bifidobacterium breve, Bifidobacterium breve ACS-071-V-Sch8b Bacteria UP000029049, UP000008279 504296465, 333110853 AEF27869.1 WP_014483567.1 fig|866777.3.peg.544 638 918 yes 1889136 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 649754 Corynebacterium ammoniagenes DSM 20306 Bacteria UP000006015 295967174 EFG80445.1 522 536 yes 1889137 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1238219 Vibrio parahaemolyticus V-223/04 Bacteria 582096649 EVU11355.1 133 133 no 1889138 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 927, 555778 Halothiobacillus neapolitanus, Halothiobacillus neapolitanus c2 Bacteria UP000009102 502585610, 261835588 ACX95355.1 WP_012823391.1 fig|555778.5.peg.501 624 629 yes 1889139 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1203561 Corynebacterium sp. KPL1824 Bacteria UP000017092 552831235, 550754074 ERS53364.1 WP_023028767.1 620 643 yes 1889140 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82996, 1348660, 682634, 1206776 Serratia plymuthica, Serratia plymuthica S13, Serratia odorifera 4Rx13, Serratia plymuthica A30 Bacteria UP000025240, UP000014900, UP000014524, UP000010163 491092354, 521009644, 514424061, 407756617 AGP42646.1, AGO53267.1, EKF66732.1 WP_004953962.1 fig|682634.3.peg.4871, fig|1206776.3.peg.336 633 647 yes 1889141 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 69823, 546271 Selenomonas sputigena, Selenomonas sputigena ATCC 35185 Bacteria UP000011124 503506005, 329746307 AEB99663.1 WP_013740666.1 fig|546271.3.peg.1415 433 435 yes 1889142 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1112214 Sphingomonas sp. PAMC 26605 Bacteria 497870188 WP_010184344.1 632 635 yes 1889143 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1005431 Escherichia coli, Escherichia coli 99.0848 Bacteria UP000036210, UP000011597 487430300, 444558953 ELV36212.1 WP_001688273.1 fig|1005431.3.peg.4855 626 631 yes 1889144 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 251698, 573066, 629258 Pseudomonas syringae pv. tabaci ATCC 11528, Pseudomonas syringae pv. aesculi str. 0893_23 Bacteria UP000034159, UP000003496 492046499, 821149199, 666927393, 331009733, 330865864 KKY53756.1, KEZ70278.1, EGH89789.1, EGH00573.1 WP_005731099.1 627 629 yes 1889145 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 364106 Escherichia coli UTI89 Bacteria UP000001952 756614449, 91074373 AJM26796.1, ABE09254.1 fig|656390.3.peg.5068, fig|1169325.3.peg.4563, fig|405955.13.peg.4463, fig|749536.3.peg.1533, fig|1181775.3.peg.3034, fig|1182672.3.peg.4309, fig|1181773.3.peg.566, fig|1182665.3.peg.5030, fig|1182662.3.peg.5137, fig|1169326.3.peg.4430, fig|1169341.3.peg.4113, fig|656388.3.peg.4996, fig|1169403.3.peg.4336, fig|1169401.3.peg.4300, fig|1182712.3.peg.1650, fig|469598.5.peg.4847, fig|1182666.3.peg.5035, fig|714962.3.peg.4500, fig|869729.3.peg.3569, fig|585035.6.peg.4362, fig|1169404.3.peg.4372, fig|752789.3.peg.1933, fig|656398.3.peg.5083, fig|1169346.3.peg.1404, fig|1169316.3.peg.4976, fig|1169317.3.peg.5262, fig|364106.7.peg.3745, fig|1181782.3.peg.4373, fig|1182709.3.peg.396, fig|1182669.3.peg.5051 626 635 yes 1889146 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 872, 665942, 457398 Desulfovibrio sp. 6_1_46AFAA, Desulfovibrio sp. 3_1_syn3 Bacteria UP000006424, UP000003982 495960859, 345046139, 302862174 EGW50031.1, EFL85108.1 WP_008685438.1 fig|457398.5.peg.2347, fig|665942.3.peg.2953 420 426 no 1889147 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 580 580 yes 1889148 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 662 668 yes 1889149 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316, 477228 Pseudomonas stutzeri, Pseudomonas sp. TS44 Bacteria UP000037382, UP000010139 489379441, 387970553 EIK54831.1 WP_003286145.1 fig|477228.3.peg.126 627 627 yes 1889150 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310636, 1310604, 1343074, 1343072, 903897, 903893, 1149135 Acinetobacter baumannii, Acinetobacter baumannii 1429530, Acinetobacter baumannii 984213, Acinetobacter baumannii CI79, Acinetobacter baumannii CI86, Acinetobacter baumannii Naval-18, Acinetobacter baumannii OIFC143, Acinetobacter baumannii 107m Bacteria UP000028632, UP000021152, UP000021300, UP000018950, UP000018917, UP000006962, UP000008755, UP000017249 446995597, 821309615, 821305657, 821304187, 821302066, 821295116, 821293095, 587826860, 587777370, 572038986, 572036691, 400388985, 395552979, 551228237 KKZ47383.1, KKZ43507.1, KKZ42069.1, KKZ39969.1, KKZ33135.1, KKZ31151.1, EXB17828.1, EXA71113.1, ETR92661.1, ETR90432.1, EJP52057.1, EJG18987.1 WP_001072853.1 fig|1116235.3.peg.1307, fig|903897.3.peg.738, fig|1221258.3.peg.1618, fig|903893.3.peg.3720, fig|933265.3.peg.908 631 635 yes 1889151 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1748, 1171373 Propionibacterium acidipropionici, Propionibacterium acidipropionici ATCC 4875 Bacteria UP000067247, UP000000214 504884893, 410824488 AFV91103.1 WP_015071995.1 fig|1171373.8.peg.3292 590 595 yes 1889152 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 889237 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni LMG 23210 Bacteria UP000065538, UP000005976 489024198, 380679561 EIB94403.1 WP_002934638.1 fig|889237.3.peg.189 430 430 yes 1889153 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76832, 883151, 883153 Myroides odoratimimus, Myroides odoratimimus CCUG 12700, Myroides odoratimimus CCUG 3837 Bacteria UP000052233, UP000014547, UP000005148 493309280, 514212939, 404603291 EPH08656.1, EKB02966.1 WP_006266783.1 fig|883151.3.peg.3016, fig|883153.3.peg.3010 604 604 yes 1889154 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 549169, 279714 Lutiella nitroferrum, Lutiella nitroferrum 2002 Bacteria UP000003165 496242555, 224600476 EEG06668.1 WP_008955940.1 fig|279714.3.peg.3947 286 286 yes 1889155 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 941449 Desulfovibrio sp. X2 Bacteria UP000014960 527034008, 523466837 EPR38729.1 WP_020881513.1 419 420 no 1889156 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 485, 528360 Neisseria gonorrhoeae, Neisseria gonorrhoeae SK-93-1035 Bacteria UP000027314, UP000002761 489798203, 268625901 EEZ58301.1 WP_003702094.1 624 633 yes 1889157 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1852, 471857 Saccharomonospora viridis, Saccharomonospora viridis DSM 43017 Bacteria UP000030848, UP000000841 506267955, 256587287 ACU98420.1 WP_015787730.1 fig|471857.5.peg.3522 545 548 yes 1889158 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1173487 Halorubrum sp. AJ67 Archaea 568635162 V6DT65 V6DT65_9EURY 303 448 no 1889159 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116036 Escherichia coli, Escherichia coli 2875150 Bacteria UP000036210, UP000012379 485783849, 476806410 ENB07444.1 WP_001406417.1 fig|1116036.3.peg.4816 626 631 yes 1889160 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 579 581 yes 1889161 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144344 Bradyrhizobium sp. YR681 Bacteria UP000007272 495415788, 398224341 EJN10652.1 WP_008140486.1 fig|1144344.3.peg.5613 623 632 yes 1889162 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 995, 929556 Flexibacter canadensis, Solitalea canadensis DSM 3403 Bacteria UP000007590 504494991, 379655814 AFD08870.1 WP_014682093.1 623 623 yes 1889163 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46429, 690566 Sphingobium chlorophenolicum, Sphingobium chlorophenolicum L-1 Bacteria UP000028411, UP000007150 503613850, 334102258 AEG49682.1 WP_013847926.1 614 622 yes 1889164 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 367190 Yersinia similis Bacteria UP000046327 644961488, 588286787, 802321590 AHK19523.1 WP_025382243.1 657 687 yes 1889165 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 849, 469605 Fusobacterium gonidiaformans, Fusobacterium sp. 3_1_5R Bacteria UP000002975 496077065, 313684667 EFS21502.1 WP_008801572.1 433 433 yes 1889166 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1125979 Rhizobium sp. PDO1-076 Bacteria UP000017669 494876891, 375054893 EHS51199.1 WP_007602981.1 fig|1125979.3.peg.2830 601 610 yes 1889167 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1352532, 1352533, 1352525, 1351799, 1351809, 1351794, 1351787, 1352513, 1352519, 1351783, 1352520, 1352518, 1352531, 1352523, 1352521, 1352515, 1352526, 1351775 Neisseria gonorrhoeae GC1-182, Neisseria gonorrhoeae CH811, Neisseria gonorrhoeae SK12684, Neisseria gonorrhoeae MU_NG4, Neisseria gonorrhoeae MU_NG18, Neisseria gonorrhoeae NOR_2011_03-06, Neisseria gonorrhoeae ATL_2011_05-13, Neisseria gonorrhoeae SK29471, Neisseria gonorrhoeae SK17973, Neisseria gonorrhoeae ATL_2011_01_17, Neisseria gonorrhoeae SK16942, Neisseria gonorrhoeae SK22871, Neisseria gonorrhoeae SK708, Neisseria gonorrhoeae SK14515, Neisseria gonorrhoeae SK16259, Neisseria gonorrhoeae SK28355, Neisseria gonorrhoeae SK8976, Neisseria gonorrhoeae SK33414 Bacteria UP000035973, UP000036301, UP000036493, UP000036500, UP000036205, UP000036476, UP000035971, UP000036252, UP000036194, UP000036192, UP000036404, UP000036428, UP000036223, UP000035944, UP000036103, UP000036358, UP000036216, UP000036284 830242700, 830217072, 830214960, 830195182, 830185120, 830177105, 830114043, 830105442, 830102380, 830100090, 830085584, 830081049, 830078191, 830073152, 830071551, 830060438, 830045075, 830044277 KLT20580.1, KLT00053.1, KLS98685.1, KLS84167.1, KLS76993.1, KLS71024.1, KLS24883.1, KLS18506.1, KLS16473.1, KLS14863.1, KLS04611.1, KLS01567.1, KLR99498.1, KLR96487.1, KLR95345.1, KLR87709.1, KLR77020.1, KLR76272.1 624 655 yes 1889168 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1175444, 1041930 Methanocella conradii, Methanocella sp. HZ254 Archaea UP000005233 504218702, 379321014 AFC99966.1 WP_014405804.1 H8I8R2 H8I8R2_METCZ 405 409 yes 1889169 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1124926, 28142 Salmonella enterica, Salmonella enterica subsp. enterica serovar Berta str. ATCC 8392, Salmonella enterica subsp. enterica serovar Berta Bacteria UP000054489, UP000017296, UP000054376 555255416, 787906596, 787906469, 554309857 KJV22092.1, KJV21973.1, ESH46028.1 WP_023238510.1 626 631 yes 1889170 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 883166 Staphylococcus simulans ACS-120-V-Sch1 Bacteria UP000001329 410875149 EKS23076.1 fig|883166.5.peg.2419 277 277 no 1889171 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 211668 Colwellia piezophila Bacteria 517859060 WP_019029268.1 646 657 yes 1889172 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1178482 Halomonas sp. BJGMM-B45 Bacteria UP000063795 546178099, 545314274 ERL51464.1 WP_021818850.1 645 645 yes 1889173 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1438791, 1328395, 1263083 Klebsiella pneumoniae, Klebsiella pneumoniae MGH-68, Klebsiella pneumoniae UCICRE 10, Klebsiella variicola CAG:634 Bacteria, Environmental samples UP000036212, UP000027511, UP000017298, UP000017950 547387609, 839732407, 821218702, 636377387, 555048848, 524234679 KMI05666.1, KKY90844.1, KDL54662.1, ESL93122.1 WP_022064760.1 626 631 yes 1889174 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 427923, 589865 Desulfurivibrio alkaliphilus, Desulfurivibrio alkaliphilus AHT2 Bacteria UP000001508 502928797, 296925436 ADH86246.1 WP_013163773.1 fig|589865.3.peg.468 430 430 yes 1889175 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1438677, 1438676, 1269010, 1281219, 1281187, 1281181, 1281178, 1281150, 1281140, 1281063, 1281043, 1281002, 1280977, 1181728, 1181765, 1169364, 1169394, 1169384, 1182664, 1181751 Escherichia coli, Escherichia coli BIDMC 73, Escherichia coli BIDMC 72, Escherichia coli 910096-2, Escherichia coli UMEA 3215-1, Escherichia coli UMEA 3122-1, Escherichia coli UMEA 3088-1, Escherichia coli UMEA 3053-1, Escherichia coli HVH 225 (4-1273116), Escherichia coli HVH 213 (4-3042928), Escherichia coli HVH 128 (4-7030436), Escherichia coli HVH 107 (4-5860571), Escherichia coli HVH 55 (4-2646161), Escherichia coli HVH 26 (4-5703913), Escherichia coli KTE182, Escherichia coli KTE219, Escherichia coli KTE85, Escherichia coli KTE157, Escherichia coli KTE129, Escherichia coli KTE57, Escherichia coli KTE205 Bacteria UP000036210, UP000027189, UP000027527, UP000017291, UP000016341, UP000016118, UP000016249, UP000016071, UP000016259, UP000016315, UP000016029, UP000016066, UP000016433, UP000016005, UP000014179, UP000014116, UP000010531, UP000010659, UP000010695, UP000010610, UP000010574 486185283, 838798259, 635832449, 635827361, 553712122, 535674235, 535541566, 535518179, 535498295, 535380366, 535333370, 535007674, 534915157, 534742125, 534632371, 508524099, 508359368, 431700772, 431638025, 431581458, 431113752, 430989788 KLX80633.1, KDG13559.1, KDG08527.1, ESE27340.1, EQY09836.1, EQW79761.1, EQW56735.1, EQW37632.1, EQV22246.1, EQU76026.1, EQR55490.1, EQQ64568.1, EQO95203.1, EQN89000.1, EOW92702.1, EOV30784.1, ELJ65702.1, ELJ06073.1, ELI53907.1, ELE17404.1, ELD06237.1 WP_001540379.1 fig|1181765.3.peg.4231, fig|1181751.3.peg.4505, fig|1169364.3.peg.4342, fig|1169384.3.peg.4396, fig|1182664.3.peg.4996, fig|1169394.3.peg.4222, fig|1181728.3.peg.4567 626 631 yes 1889176 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 411361, 1227487 Halosarcina pallida, Halosarcina pallida JCM 14848 Archaea 495658832, 445681996 ELZ34420.1 WP_008383411.1 M0DG32 M0DG32_9EURY 457 488 yes 1889177 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 3694 Populus trichocarpa Plants UP000006729 UP000006729 566150962, 550348168 ERP66127.1 XP_006369558.1 336 412 no 1889178 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 365349, 1192197 Pelosinus fermentans, Pelosinus fermentans JBW45 Bacteria UP000005361 495233014, 763686071 AJQ28321.1 WP_007957785.1 fig|1192197.3.peg.2752 432 432 yes 1889179 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40989, 882082 Saccharomonospora cyanea, Saccharomonospora cyanea NA-134 Bacteria UP000002791 491602057, 374663491 EHR63369.1 WP_005459619.1 543 546 yes 1889180 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 380, 1117943 Sinorhizobium fredii, Sinorhizobium fredii HH103 Bacteria UP000007735 504098579, 365184085 WP_014332573.1 fig|380.5.peg.6019 605 611 yes 1889181 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 502 512 yes 1889182 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1001586 Leptospira interrogans serovar Bulgarica str. Mallika Bacteria UP000006609 400351615 EJP03834.1 212 222 no 1889183 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 308 318 no 1889184 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324, 1235458 Stenotrophomonas maltophilia, Stenotrophomonas maltophilia AU12-09 Bacteria UP000034806, UP000011974 491561513, 460866875 EMI48633.1 WP_005419099.1 fig|1235458.3.peg.2951 613 614 yes 1889185 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2203, 323259 Methanospirillum hungatei, Methanospirillum hungatei JF-1 Archaea UP000001941 499767441, 88187900 ABD40897.1 WP_011448175.1 Q2FP19 Q2FP19_METHJ fig|323259.5.peg.1206 395 403 no 1889186 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1131552 Methylomonas sp. MK1 Bacteria 521973287 WP_020484558.1 621 622 yes 1889187 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 891974 Plautia stali symbiont Bacteria UP000016901 498302743, 549067894 WP_010616899.1 631 640 yes 1889188 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317, 1095103, 1194078, 1194395 Pseudomonas syringae, Pseudomonas syringae pv. actinidiae ICMP 18884, Pseudomonas syringae pv. actinidiae ICMP 18801, Pseudomonas syringae pv. actinidiae ICMP 19097 Bacteria UP000028642, UP000025140, UP000015875, UP000015811 516279208, 620043618, 519322834, 519312948 KAK37340.1, EPN82686.1, EPN73979.1 WP_017683171.1 627 629 yes 1889189 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 997878, 997879 Bacteroides fragilis, Bacteroides fragilis CL03T00C08, Bacteroides fragilis CL03T12C07 Bacteria UP000036847, UP000003838, UP000003014 492246151, 392652644, 392649918 EIY46302.1, EIY43590.1 WP_005788048.1 fig|997879.3.peg.3614, fig|997878.3.peg.2472 564 564 yes 1889190 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406, 1413214 Paenibacillus polymyxa, Paenibacillus polymyxa SQR-21 Bacteria UP000031922, UP000019588 644725689, 723616722, 595632175 AIY10095.1, AHM64433.1 WP_025364021.1 591 614 yes 1889191 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 654, 1073383 Aeromonas veronii, Aeromonas veronii AMC34 Bacteria UP000051545, UP000006087 491485206, 404624896 EKB21714.1 WP_005342947.1 fig|1073383.3.peg.1282 645 663 yes 1889192 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2172, 224719 Methanobrevibacter sp. AbM4 Archaea UP000014066 511305868, 509083826 AGN16072.1 WP_016357775.1 R9SH39 R9SH39_9EURY 432 434 yes 1889193 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262885 Eubacterium sp. CAG:248 Environmental samples UP000018194 547795689, 524417759 WP_022205615.1 434 435 yes 1889194 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262790 Clostridium sp. CAG:277 Environmental samples UP000018281 548247331, 524769339 WP_022465191.1 434 435 yes 1889195 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29508, 1193051 Leptospira meyeri, Leptospira meyeri serovar Hardjo str. Went 5 Bacteria UP000007992 490923568, 408463227 EKJ86952.1 WP_004785437.1 fig|1193051.3.peg.388 499 503 yes 1889196 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168935 Thalassospira lucentensis Bacteria 550981999 WP_022730099.1 597 600 yes 1889197 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310581 Acinetobacter baumannii, Acinetobacter baumannii 34654 Bacteria UP000028632, UP000020896 691041387, 588041652 EXD23676.1 WP_031992181.1 621 625 yes 1889198 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 991997 Vibrio cholerae, Vibrio cholerae BJG-01 Bacteria UP000028983, UP000004304 445993252, 341649284 EGS73277.1 WP_000071107.1 fig|991997.6.peg.893 639 645 yes 1889199 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 1095659, 991998 Vibrio cholerae, Vibrio cholerae O1 str. 87395, Vibrio cholerae HE-09 Bacteria UP000028983, UP000012090, UP000005295 445993253, 669350117, 469679959, 341639393 KFD80535.1, EMP96021.1, EGS64011.1 WP_000071108.1 fig|1095659.3.peg.56, fig|991998.7.peg.486 639 645 yes 1889200 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 592313 Vibrio cholerae, Vibrio cholerae 12129(1) Bacteria UP000028983, UP000005032 445993250, 229335421 EEO00904.1 WP_000071105.1 fig|592313.3.peg.253 639 645 yes 1889201 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 140100, 593585 Vibrio albensis, Vibrio cholerae bv. albensis VL426 Bacteria UP000054169, UP000005144 445993251, 229338545 EEO03562.1 WP_000071106.1 fig|593585.3.peg.1553 639 645 yes 1889202 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 593590 Vibrio cholerae, Vibrio cholerae TMA 21 Bacteria UP000028983, UP000005582 445993256, 229347161 EEO12122.1 WP_000071111.1 fig|593590.3.peg.3592 639 645 yes 1889203 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2322, 644295 Methanohalobium evestigatum, Methanohalobium evestigatum Z-7303 Archaea UP000000391 502959243, 298674697, 298287685 ADI73651.1 WP_013194219.1, YP_003726447.1 D7E727 D7E727_METEZ 427 427 yes 1889204 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 437898, 762967 Sutterella parvirubra, Sutterella parvirubra YIT 11816 Bacteria UP000004956 495818005, 378597817 EHY31056.1 WP_008542584.1 fig|762967.3.peg.1229 382 382 yes 1889205 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 470, 1310627 Acinetobacter baumannii, Acinetobacter baumannii 1284800 Bacteria UP000028632, UP000027056 757516781, 630494467 KCY04067.1 WP_042781610.1 91 91 no 1889206 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1084, 1150469 Rhodospirillum photometricum, Rhodospirillum photometricum DSM 122 Bacteria UP000033220 504227601, 378402948 WP_014414703.1 561 564 yes 1889207 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630, 994476 Yersinia enterocolitica, Yersinia enterocolitica subsp. palearctica 105.5R(r) Bacteria UP000029427, UP000009271 503414421, 755413997, 685179136, 685168578, 325664149, 812174743, 802325951 AJJ27008.1, KGA66747.1, KGA56267.1, ADZ40793.1 WP_013649082.1 fig|940289.3.peg.3736, fig|994476.3.peg.312 634 655 yes 1889208 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317, 1324931, 1365665, 629270 Pseudomonas syringae, Pseudomonas syringae pv. syringae B301D, Pseudomonas syringae pv. syringae str. B301D-R, Pseudomonas syringae pv. aceris str. M302273PT Bacteria UP000028642, UP000034018, UP000019858, UP000004879 489497951, 817606176, 590452540, 330971523 AKF44158.1, EXL29346.1, EGH71589.1 WP_003402862.1 627 629 yes 1889209 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204, 1073353 Campylobacter showae, Campylobacter sp. CC57C Bacteria UP000011782 489043336, 459277734 EMG29759.1 WP_002953636.1 fig|1073353.3.peg.2188 443 444 yes 1889210 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392003 Mycobacterium avium 11-0986 Bacteria UP000029542 564205494 ETB40609.1 460 461 yes 1889211 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1487582 Peptococcaceae bacterium SCADC Bacteria UP000028991 738844769, 672908380, 672906497, 669259898 KFI37412.1, KFI35691.1, KFD41745.1 WP_036734282.1 433 433 yes 1889212 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262903 Methanoculleus sp. CAG:1088 Archaea UP000018376 548649871, 524838020 WP_022532575.1 R7PZF1 R7PZF1_9EURY 437 441 yes 1889213 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 637 640 yes 1889214 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446558, 1446567, 1446571, 1446559, 1446563 Escherichia coli, Escherichia coli O121:H19 str. 2009EL1302, Escherichia coli O121:H19 str. 2010C-4989, Escherichia coli O121:H19 str. 2011C-3216, Escherichia coli O121:H19 str. 2009EL1412, Escherichia coli O121:H19 str. 2010C-4254 Bacteria UP000036210, UP000024109, UP000024292, UP000023954, UP000023963, UP000023832 693040801, 796817611, 788892413, 788877263, 607808212, 606794928, 606775852, 606516124, 606414414 KJY08409.1, KJW43302.1, KJW28887.1, EZE87912.1, EYY34723.1, EYY16712.1, EYV71156.1, EYU73823.1 WP_032212910.1 626 631 yes 1889215 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 283909 Capitella teleta Invertebrates 443725941 ELU13313.1 425 430 no 1889216 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158170 Thioalkalivibrio sp. ALE12 Bacteria 518388140 WP_019558347.1 627 629 yes 1889217 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262900 Fusobacterium sp. CAG:649 Environmental samples UP000017972 547450361, 524244292 WP_022069983.1 433 433 yes 1889218 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053250 Bacillus cereus, Bacillus cereus VDM062 Bacteria UP000036076, UP000006961 488120871, 401311131 EJS16439.1 WP_002192268.1 fig|1053250.3.peg.587 586 586 yes 1889219 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116135 Escherichia coli, Escherichia coli MP021552.12 Bacteria UP000036210, UP000012414 487414361, 476040581 EMU65949.1 WP_001681899.1 fig|1116135.3.peg.4506 626 631 yes 1889220 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262895 Eubacterium sp. CAG:86 Environmental samples UP000017940 546468753, 523998060 WP_021866930.1 434 435 yes 1889221 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 88036 Selaginella moellendorffii Plants UP000001514 302793765, 300153456 EFJ20094.1 XP_002978647.1 316 454 no 1889222 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 876, 525146 Desulfovibrio desulfuricans, Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Bacteria UP000002598 501718542, 219868202 ACL48537.1 WP_012624264.1 fig|525146.3.peg.731 419 426 no 1889223 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314330 Enterobacter sp. DC1 Bacteria UP000019282 695736508, 584245324 EWG64791.1 WP_032662964.1 626 631 yes 1889224 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487 Neisseria meningitidis Bacteria UP000050419 610425856 AHW74732.1 625 671 yes 1889225 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217418 Cupriavidus necator HPC(L) Bacteria UP000053474 493626387, 554360836 ESH97979.1 WP_006578514.1 629 632 yes 1889226 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1402533, 1402507 Pseudomonas aeruginosa, Pseudomonas aeruginosa BWHPSA041, Pseudomonas aeruginosa BWHPSA007 Bacteria UP000065817, UP000021615, UP000017283 518556757, 574056057, 552693074 ETV32671.1, ERZ06585.1 WP_019726964.1 627 627 yes 1889227 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570924 Thermus sp. NMX2.A1 Bacteria UP000018848 740187541, 568399448 ETN88983.1 WP_038029669.1 433 435 yes 1889228 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 157784 Pseudomonas thermotolerans Bacteria 516564241 WP_017939427.1 627 627 yes 1889229 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 1310162, 1295400, 1295394, 889225, 757425, 360112, 360108 Campylobacter jejuni, Campylobacter jejuni BJ-CJD101, Campylobacter jejuni subsp. jejuni ICDCCJ07004, Campylobacter jejuni ICDCCJ07002, Campylobacter jejuni subsp. jejuni 1997-11, Campylobacter jejuni subsp. jejuni ICDCCJ07001, Campylobacter jejuni subsp. jejuni HB93-13, Campylobacter jejuni subsp. jejuni 260.94 Bacteria UP000065538, UP000030756, UP000014010, UP000014004, UP000003363, UP000008121, UP000003450, UP000003151 488944029, 527844623, 477596552, 477594404, 380647935, 315017722, 85842764, 85841386 EPW32970.1, ENI13561.1, ENI11468.1, EIB64820.1, ADT65815.1, EAQ59976.1, EAQ58634.1 WP_002855104.1 fig|757425.3.peg.509, fig|889225.3.peg.551, fig|360108.3.peg.1639, fig|1295400.3.peg.1061, fig|360112.3.peg.405, fig|1295394.3.peg.1684 430 430 yes 1889230 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83341, 1108045 Gordonia rhizosphera, Gordonia rhizosphera NBRC 16068 Bacteria UP000008363 493379879, 403203807 WP_006336148.1 fig|1108045.3.peg.4075 546 550 yes 1889231 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 77133 uncultured bacterium Environmental samples UP000041370 406937145 EKD70685.1 548 549 yes 1889232 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262979 Tannerella sp. CAG:51 Environmental samples UP000018150 548167703, 524677709 WP_022389668.1 565 565 yes 1889233 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 585346738 WP_024228356.1 626 631 yes 1889234 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1000569 Megasphaera sp. UPII 135-E Bacteria UP000004137 494635054, 341589343 EGS32624.1 WP_007392998.1 431 432 yes 1889235 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 346, 1156940 Xanthomonas citri, Xanthomonas citri pv. mangiferaeindicae LMG 941 Bacteria UP000004140 489578883, 380689278 WP_003483329.1 fig|1156940.3.peg.809 624 625 yes 1889236 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 332056, 452662 Sphingobium japonicum, Sphingobium japonicum UT26S Bacteria UP000007753 502806452, 292676684 WP_013041428.1 fig|452662.3.peg.3162 611 619 yes 1889237 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 293256, 1121439 Desulfovibrio alkalitolerans, Desulfovibrio alkalitolerans DSM 16529 Bacteria UP000014975 527043575, 523462345 EPR34317.1 WP_020886779.1 415 419 no 1889238 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316, 1212549 Pseudomonas stutzeri, Pseudomonas stutzeri B1SMN1 Bacteria UP000037382, UP000014842 520865396, 516323552 EPL64289.1 WP_020305817.1 627 627 yes 1889239 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1426, 634956 Geobacillus thermoglucosidasius, Geobacillus thermoglucosidasius C56-YS93 Bacteria UP000033360, UP000007149 503643454, 335363668 AEH49348.1 WP_013877530.1 573 573 yes 1889240 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1460641 Bacillus sp. JCM 19047 Bacteria UP000019370 737415178, 585382358 WP_035396178.1 590 590 yes 1889241 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1326980 Sulfolobales archaeon AZ1 Archaea UP000054284 583848118 EWG07812.1 W7KYH0 W7KYH0_9CREN 421 421 yes 1889242 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 249 250 no 1889243 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 95606 Sphingomonas-like bacterium B12 Bacteria 550943880 WP_022692282.1 280 282 no 1889244 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 930166 Pseudomonas brassicacearum Bacteria UP000060335 643459263, 591390970 AHL31863.1 WP_025211519.1 628 629 yes 1889245 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053232 Bacillus cereus, Bacillus cereus VD131 Bacteria UP000036076, UP000014014 507035566, 500400890 EOP16747.1 WP_016107259.1 fig|1053232.3.peg.5928 586 586 yes 1889246 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1145134, 1145133, 1145132, 1095665, 1095675, 1095694 Neisseria meningitidis, Neisseria meningitidis 97027, Neisseria meningitidis 64182, Neisseria meningitidis 65012, Neisseria meningitidis 63006, Neisseria meningitidis 65014, Neisseria meningitidis 63041 Bacteria UP000050419, UP000013342, UP000013362, UP000013319, UP000010736, UP000010751, UP000010761 488175969, 485305932, 485299846, 485299490, 432274988, 432251342, 432213197 EOB70477.1, EOB64781.1, EOB64458.1, ELL30066.1, ELL06711.1, ELK69122.1 WP_002247177.1 fig|1145132.3.peg.2615, fig|1095675.3.peg.2719, fig|1095694.3.peg.2757, fig|1095665.3.peg.2642, fig|1145133.3.peg.2599, fig|1145134.3.peg.2589 625 633 yes 1889247 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 191028, 1002340, 1577898, 1577899 Phaeobacter gallaeciensis ANG1, Leisingera sp. ANG-S, Leisingera sp. ANG-S3 Bacteria UP000031201, UP000031185, UP000031455 518124448, 743076074, 742742351, 742714365 KID08244.1, KIC53306.1, KIC25966.1 WP_019294656.1 596 604 yes 1889248 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54252, 694429 Pyrolobus fumarii, Pyrolobus fumarii 1A Archaea UP000001037 503792989, 343460870 AEM39306.1 WP_014026983.1 G0EH82 G0EH82_PYRF1 432 433 yes 1889249 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 937772 gamma proteobacterium IMCC1989 Bacteria UP000010300 497355977, 330419452 EGG93849.1 WP_009670190.1 626 627 yes 1889250 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 710685 Mycobacterium rhodesiae NBB3 Bacteria UP000005442 359819055 AEV71868.1 fig|710685.3.peg.1253 484 493 yes 1889251 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 452627 Amphritea japonica Bacteria 518452331 WP_019622538.1 624 626 yes 1889252 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1081893 Escherichia coli, Escherichia coli T924_01 Bacteria UP000036210, UP000016314 545142774, 536900913 ERC81626.1 WP_021501418.1 626 631 yes 1889253 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1402, 766760 Bacillus licheniformis, Bacillus licheniformis 9945A Bacteria UP000036721, UP000014068 521286386, 510141683 AGN35414.1 WP_020450654.1 fig|766760.3.peg.1034 591 591 yes 1889254 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 225991, 1457173 Comamonas aquatica, Comamonas aquatica DA1877 Bacteria UP000020766 759669461, 594554761 EXU78805.1 WP_043386970.1 625 644 yes 1889255 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263063 Clostridium bartlettii CAG:1329 Environmental samples UP000017980 547452515, 524245858 WP_022072058.1 434 434 yes 1889256 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 320324, 1347342 Formosa agariphila, Formosa agariphila KMM 3901 Bacteria UP000016160 740744218, 537741728 WP_038529504.1 618 618 yes 1889257 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 303682 Thauera sp. 28 Bacteria UP000013096 489022244, 479303024 ENO91124.1 WP_002932728.1 638 638 yes 1889258 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 320799, 1223545 Gordonia soli, Gordonia soli NBRC 108243 Bacteria UP000011666 494898798, 443885393 WP_007624843.1 fig|1223545.3.peg.4616 551 559 yes 1889259 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 77133 uncultured bacterium Environmental samples UP000041370 406878490 EKD27381.1 535 535 yes 1889260 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1565415 Streptomyces sp. DUT180 Bacteria 515469003 WP_016906330.1 594 598 yes 1889261 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 214, 936155 Helicobacter felis, Helicobacter felis ATCC 49179 Bacteria UP000007934 503234021, 315131682 WP_013468682.1 fig|936155.3.peg.246 444 445 yes 1889262 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262921 Prevotella sp. CAG:1185 Environmental samples UP000018054 547227442, 524105058 WP_021964452.1 565 566 yes 1889263 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 1659703, 1340854 Enterobacter sp. GN02226, Enterobacter cloacae str. Hanford Bacteria UP000036272, UP000014965 527036243, 829456420, 523467901 KLR46969.1, EPR39765.1 WP_020882985.1 626 631 yes 1889264 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 347483, 1163407 Rhodanobacter spathiphylli, Rhodanobacter spathiphylli B39 Bacteria UP000003226 495083298, 388435840 EIL92732.1 WP_007808122.1 fig|1163407.3.peg.2128 608 610 yes 1889265 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1131285 zeta proteobacterium SCGC AB-137-I08 Bacteria 517098789 WP_018287607.1 618 619 yes 1889266 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 159749 Thalassiosira oceanica Plants UP000007974 397572785 EJK48404.1 543 739 yes 1889267 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 313627 Bacillus sp. NRRL B-14911 Bacteria UP000004554 89084433 EAR63583.1 581 581 yes 1889268 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1144666, 1144668, 981333 Acinetobacter sp. CIP 102143, Acinetobacter sp. CIP 102529, Acinetobacter parvus DSM 16617 Bacteria UP000018424, UP000018446, UP000023776 490818656, 480346613, 479944082, 479887048 ENX66680.1, ENU90389.1, ENU37368.1 WP_004680755.1 fig|1144668.3.peg.99, fig|1144666.3.peg.787, fig|981333.3.peg.1716 626 631 yes 1889269 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43080, 427318 Sulfolobus islandicus, Sulfolobus islandicus M.16.27 Archaea UP000002307 502138132, 228019523, 259517494 ACP54930.1 WP_012718704.1 C3N4K5 THIC_SULIA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7258817 432 433 yes 1889270 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281195, 945433 Escherichia coli, Escherichia coli UMEA 3152-1, Escherichia coli WV_060327 Bacteria UP000036210, UP000016322, UP000003756 485728995, 535558321, 320197111 EQW96135.1, EFW71729.1 WP_001356990.1 fig|945433.3.peg.585, fig|562.376.peg.134 626 631 yes 1889271 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 617 636 yes 1889272 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1124955 Salmonella enterica, Salmonella enterica subsp. enterica serovar Miami str. 1923 Bacteria UP000054489, UP000017310 555233872, 554206322 ESG44572.1 WP_023220658.1 626 631 yes 1889273 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 519089807 WP_020245682.1 626 631 yes 1889274 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 38323, 1134508, 1134509, 1402979, 1402980 Bartonella henselae, Bartonella henselae JK 53, Bartonella henselae str. Zeus, Bartonella henselae JK 41, Bartonella henselae JK 42 Bacteria UP000019802, UP000027158, UP000027273, UP000018960, UP000018959 736432117, 654332568, 654328385, 572289491, 572284937, 605048378 KEC62333.1, KEC57995.1, ETS12300.1, ETS07884.1 WP_034454221.1 601 610 yes 1889275 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1299334, 1299333 Mycobacterium xenopi 4042, Mycobacterium xenopi 3993 Bacteria UP000023198 576475184, 576429110 EUA68730.1, EUA22819.1 171 187 no 1889276 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1119528 Methyloversatilis sp. FAM1 Bacteria 518759084 WP_019916543.1 638 638 yes 1889277 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 862513 Neisseria meningitidis ATCC 13091 Bacteria UP000005526 304337383 EFM03556.1 625 658 yes 1889278 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 190893, 1384040 Vibrio coralliilyticus, Vibrio coralliilyticus OCN008 Bacteria UP000033403, UP000016334 545087917, 536746510 ERB63639.1 WP_021457721.1 640 646 yes 1889279 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632, 992177 Yersinia pestis, Yersinia pestis PY-95 Bacteria UP000000815 UP000031825, UP000005995 488358931, 391689720 EIT22815.1 WP_002428316.1 fig|992173.3.peg.4071, fig|992157.3.peg.3912, fig|992167.3.peg.3761, fig|992159.3.peg.3720, fig|992133.3.peg.4185, fig|992146.3.peg.4076, fig|992147.3.peg.4083, fig|992170.3.peg.4053, fig|992171.3.peg.4041, fig|992174.3.peg.3910, fig|992139.3.peg.4156, fig|992166.3.peg.3685, fig|992160.3.peg.3896, fig|992178.3.peg.4106, fig|992162.3.peg.3907, fig|992136.3.peg.3935, fig|992185.3.peg.3774, fig|992150.3.peg.3812, fig|992176.3.peg.3875, fig|992154.3.peg.3836, fig|992137.3.peg.4106, fig|992177.3.peg.4111, fig|992145.3.peg.4172, fig|992149.3.peg.4129, fig|992144.3.peg.3952 442 453 yes 1889280 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151372 Clostridium difficile F501 Bacteria UP000015712 531527838 EQI12126.1 81 82 no 1889281 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28132, 575612 Prevotella melaninogenica, Prevotella melaninogenica D18 Bacteria UP000003989 490494943, 288333978 EFC72422.1 WP_004361131.1 525 525 yes 1889282 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992174 Yersinia pestis, Yersinia pestis PY-92 Bacteria UP000000815 UP000031825, UP000005991 488358429, 391675989 EIT10455.1 WP_002427814.1 179 207 no 1889283 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 512565 Actinoplanes missouriensis 431 Bacteria UP000007882 381369046 456 507 yes 1889284 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 992185, 992176, 992174, 992170, 992167, 992162, 992160, 992154, 992150, 992149, 992146, 992147, 992145, 992144, 992139, 992136 Yersinia pestis PY-113, Yersinia pestis PY-94, Yersinia pestis PY-92, Yersinia pestis PY-88, Yersinia pestis PY-71, Yersinia pestis PY-61, Yersinia pestis PY-59, Yersinia pestis PY-52, Yersinia pestis PY-45, Yersinia pestis PY-42, Yersinia pestis PY-32, Yersinia pestis PY-34, Yersinia pestis PY-29, Yersinia pestis PY-25, Yersinia pestis PY-13, Yersinia pestis PY-10 Bacteria UP000006018, UP000005691, UP000005991, UP000003581, UP000005703, UP000003504, UP000003918, UP000004366, UP000003090, UP000003689, UP000003270, UP000004134, UP000003008, UP000005318, UP000004911, UP000003852 391726218, 391676144, 391675928, 391648685, 391633695, 391609893, 391596125, 391564849, 391536939, 391534587, 391519270, 391518496, 391517357, 391506433, 391485243, 391469397 EIT55597.1, EIT10585.1, EIT10397.1, EIS86168.1, EIS73064.1, EIS52243.1, EIS40092.1, EIS13012.1, EIR87876.1, EIR85754.1, EIR71919.1, EIR71206.1, EIR70171.1, EIR60353.1, EIR41411.1, EIR27179.1 fig|992173.3.peg.4071, fig|992157.3.peg.3912, fig|992160.3.peg.3896, fig|992162.3.peg.3907, fig|992167.3.peg.3761, fig|992146.3.peg.4076, fig|992185.3.peg.3774, fig|992159.3.peg.3720, fig|992150.3.peg.3812, fig|992133.3.peg.4185, fig|992154.3.peg.3836, fig|992147.3.peg.4083, fig|992170.3.peg.4053, fig|992171.3.peg.4041, fig|992177.3.peg.4111, fig|992174.3.peg.3910, fig|992139.3.peg.4156, fig|992136.3.peg.3935, fig|992166.3.peg.3685, fig|992145.3.peg.4172, fig|992149.3.peg.4129, fig|992176.3.peg.3875, fig|992137.3.peg.4106, fig|992144.3.peg.3952, fig|992178.3.peg.4106 430 441 yes 1889285 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2173 Methanobrevibacter smithii Archaea 518093182 WP_019263390.1 419 420 yes 1889286 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324, 1333853 Stenotrophomonas maltophilia, Stenotrophomonas maltophilia MF89 Bacteria UP000034806, UP000016053 544779912, 533225185 EQM80086.1 WP_021203613.1 613 614 yes 1889287 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 174, 1193007 Leptospira borgpetersenii, Leptospira borgpetersenii str. 200701203 Bacteria UP000011783 490410285, 456887503 EMF98545.1 WP_004283194.1 516 517 yes 1889288 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1261060 Gardnerella vaginalis JCP7672 Bacteria UP000014621 514592107 EPI53419.1 609 872 yes 1889289 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65958, 1234668 Gluconacetobacter oboediens, Gluconacetobacter xylinus NBRC 13693 Bacteria UP000032683 498200038, 775246740 WP_010514194.1 605 613 yes 1889290 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 936563 Fusobacterium sp. CM22 Bacteria UP000020631 696271293, 576668736 EUB19924.1 WP_032847734.1 433 433 yes 1889291 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 745310 Sphingomonas sp. MM-1 Bacteria UP000011816 505271200, 469479066 AGH49291.1 WP_015458302.1 613 621 yes 1889292 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 381445 Amycolatopsis nigrescens Bacteria 522158702 WP_020669910.1 542 545 yes 1889293 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 224911, 374 Bradyrhizobium japonicum USDA 110 Bacteria UP000002526 UP000002526 27381770, 499401932, 47606163, 27354939 NP_773299.1, WP_011089399.1 Q89FP0 THIC_BRADU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 321870 fig|224911.1.peg.6659 623 632 yes 1889294 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397532 Marinobacter sp. EVN1 Bacteria UP000017112 550790927 ERS88690.1 585 585 yes 1889295 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 89053, 1220574 Gordonia amicalis, Gordonia amicalis NBRC 100051 = JCM 11271 Bacteria UP000035024 493480117, 441452798 WP_006435015.1 fig|1220574.3.peg.729 551 563 yes 1889296 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1216470 Enterobacter sp. SST3 Bacteria UP000006268 495778884, 400213779 EJO44716.1 WP_008503463.1 fig|1216470.3.peg.4167 626 631 yes 1889297 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144708 Pseudomonas sp. GM41(2012) Bacteria UP000007282 495428666, 576710361 EUB76792.1 WP_008153363.1 627 629 yes 1889298 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1284352 Paenibacillus sp. A9 Bacteria 516424533 WP_017813931.1 580 580 yes 1889299 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 91359 Enterovibrio calviensis Bacteria 515580502 WP_017013236.1 637 637 yes 1889300 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 319017 Bradyrhizobium sp. WSM471 Bacteria UP000005774 494887614, 374425630 EHR05163.1 WP_007613661.1 623 632 yes 1889301 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1827, 191292, 931223, 1429046, 1301088 Rhodococcus aetherivorans, Rhodococcus sp. BCP1, Rhodococcus rhodochrous ATCC 21198, Rhodococcus sp. EsD8 Bacteria UP000034779, UP000019064, UP000013013 493995565, 816217373, 634564951, 573523663, 482631892 AKE91169.1, KDE12093.1, ETT23379.1 WP_006938227.1 fig|1301088.3.peg.2861 526 538 yes 1889302 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 879567, 1322246 Desulfovibrio sp. C1TLV30, Desulfovibrio piezophilus C1TLV30 Bacteria UP000011724 505227014, 451895184 WP_015414116.1 434 434 yes 1889303 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1076, 258594 Rhodopseudomonas palustris, Rhodopseudomonas palustris CGA009 Bacteria UP000032515, UP000001426 499472477, 47606075, 39650495 WP_011159117.1 P61427 THIC_RHOPA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 573033 fig|258594.1.peg.3558 656 666 yes 1889304 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 889241 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni LMG 23223 Bacteria UP000065538, UP000003068 488961861, 380603562 EIB23653.1 WP_002872885.1 fig|889241.3.peg.1337 430 430 yes 1889305 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 92490 Erwinia toletana Bacteria 516413656 WP_017803054.1 634 647 yes 1889306 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1208661 Cronobacter dublinensis 582 Bacteria UP000009361 426285431 285 289 no 1889307 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1208661 Cronobacter dublinensis 582 Bacteria UP000009361 426285430 316 319 yes 1889308 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1772, 246196 Mycobacterium smegmatis, Mycobacterium smegmatis str. MC2 155 Bacteria UP000029911, UP000029906 500045984, 118470952, 698956144, 698947861, 698938668, 399229134, 118172239 AIU18679.1, AIU12055.1, AIU05430.1, AFP36627.1, ABK73135.1 WP_011726702.1, YP_884565.1 1744730 fig|246196.1.peg.143 391 475 no 1889309 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 649831 Actinoplanes sp. N902-109 Bacteria UP000013541 505431934, 492003158 AGL14478.1 WP_015619036.1 fig|649831.3.peg.958 525 527 yes 1889310 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36809 Mycobacterium abscessus Bacteria UP000046141 515775192 WP_017207792.1 550 551 yes 1889311 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1439940 Pseudomonas sp. BAY1662 Bacteria UP000019475 739175985, 588311470 EXF45337.1 WP_037039995.1 627 627 yes 1889312 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 129922 Saccharomonospora halophila Bacteria 518639153 WP_019809290.1 541 557 yes 1889313 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 155194, 1094491 Bartonella bovis, Bartonella bovis 91-4 Bacteria UP000014038 498387018, 478418412 ENN92114.1 WP_010700981.1 598 608 yes 1889314 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1800, 710421 Mycobacterium chubuense, Mycobacterium chubuense NBB4 Bacteria UP000036176, UP000006057 504626712, 390614172 AFM15322.1 WP_014813814.1 fig|710421.3.peg.493 516 524 yes 1889315 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1131277 alpha proteobacterium SCGC AB-629-F11 Bacteria 516677003 WP_018036140.1 187 187 no 1889316 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1118156 Stenotrophomonas maltophilia SKK35 Bacteria UP000012178 475006150 fig|1118156.3.peg.3111 614 646 yes 1889317 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173365, 697282 Methylobacter tundripaludum, Methylobacter tundripaludum SV96 Bacteria UP000004664 493947957, 344263357 EGW23628.1 WP_006891877.1 625 626 yes 1889318 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 380021, 1124983, 1420599 Pseudomonas sp. CHA0, Pseudomonas fluorescens CHA0, Pseudomonas protegens Cab57 Bacteria UP000013940, UP000031621 505446821, 500240188, 610524495 AGL82346.1 WP_015633923.1 fig|1124983.3.peg.553 628 629 yes 1889319 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1029983, 1194151 Salmonella enterica, Salmonella enterica subsp. enterica serovar Abony str. 0014, Salmonella enterica subsp. enterica serovar Norwich str. CFSAN001077 Bacteria UP000054489, UP000017326, UP000017371 555263136, 605547959, 554441855 AHW26537.1, ESJ64406.1 WP_023244818.1 626 631 yes 1889320 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65093 Halothece sp. PCC 7418 Bacteria UP000010481 505039031, 428690964 AFZ44258.1 WP_015226133.1 fig|65093.3.peg.2224 457 458 yes 1889321 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35795, 1423892 Ehrlichia muris, Ehrlichia muris AS145 Bacteria UP000018689 568197549, 566059796 AHC39099.1 WP_024071913.1 553 553 yes 1889322 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1083, 1150626 Phaeospirillum molischianum, Phaeospirillum molischianum DSM 120 Bacteria UP000004169 488817881, 380682409 WP_002730287.1 fig|1150626.3.peg.2878 605 611 yes 1889323 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 523831 Salmonella enterica, Salmonella enterica subsp. houtenae str. ATCC BAA-1581 Bacteria UP000054489, UP000004436 446030430, 379049242 EHY67137.1 WP_000108285.1 fig|523831.5.peg.4109 626 631 yes 1889324 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717, 698970 Corynebacterium diphtheriae, Corynebacterium diphtheriae HC04 Bacteria UP000033584, UP000007154 504075007, 372113960 AEX80018.1 WP_014309001.1 fig|698970.3.peg.29 592 599 yes 1889325 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324 Stenotrophomonas maltophilia Bacteria UP000034806 498169826 WP_010483982.1 613 614 yes 1889326 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423 Bacillus subtilis Bacteria UP000030083 727791032, 635177857 KDE21901.1 WP_033885177.1 590 590 yes 1889327 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29360, 642492 Clostridium lentocellum, Clostridium lentocellum DSM 5427 Bacteria UP000008467 503421525, 326541028 ADZ82887.1 WP_013656186.1 435 435 yes 1889328 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 469606 Fusobacterium nucleatum, Fusobacterium sp. 4_1_13 Bacteria UP000004925 496078766, 229430476 EEO40688.1 WP_008803273.1 fig|469606.3.peg.909 433 433 yes 1889329 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 155892, 1292034 Caulobacter vibrioides, Caulobacter crescentus OR37 Bacteria UP000053705, UP000013063 490756218, 480899348 ENZ82310.1 WP_004618518.1 fig|1292034.3.peg.1854 612 612 3EPO, 3EPN, 4S2A yes 1889330 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 517, 568707, 518, 1427985, 1331228, 1331233, 1331240, 1331245, 1331242, 1331243, 1331241, 1331238, 1331236, 1331237, 1331234, 1331235, 1331232, 1331231, 1331229, 1331230, 1331227, 1331226, 1331225, 1331224, 1331223, 1331221, 1331222, 1331220, 1331219, 1331218, 1331215, 1331213, 1331214, 1331260, 1458262, 1458266, 1458261, 1458265, 1458260, 1458259, 1331204, 1458269, 1331203, 1458263, 1458258, 1458257, 1458256, 1331201, 1331200, 1331250, 1331199, 1331198, 1331216, 1331239, 1458264, 1331254, 1208659, 1208657, 1208658, 257310, 257311, 519 Bordetella bronchiseptica 253, Bordetella bronchiseptica, Bordetella bronchiseptica KM22, Bordetella bronchiseptica MBORD678, Bordetella bronchiseptica MBORD762, Bordetella bronchiseptica MO275, Bordetella bronchiseptica SO10328, Bordetella bronchiseptica OSU553, Bordetella bronchiseptica RB630, Bordetella bronchiseptica OSU095, Bordetella bronchiseptica MBORD901, Bordetella bronchiseptica MBORD839, Bordetella bronchiseptica MBORD849, Bordetella bronchiseptica MBORD782, Bordetella bronchiseptica MBORD785, Bordetella bronchiseptica MBORD731, Bordetella bronchiseptica MBORD707, Bordetella bronchiseptica MBORD681, Bordetella bronchiseptica MBORD698, Bordetella bronchiseptica MBORD675, Bordetella bronchiseptica MBORD670, Bordetella bronchiseptica MBORD668, Bordetella bronchiseptica MBORD665, Bordetella bronchiseptica MBORD635, Bordetella bronchiseptica MBORD624, Bordetella bronchiseptica MBORD632, Bordetella bronchiseptica MBORD595, Bordetella bronchiseptica MBORD591, Bordetella bronchiseptica M85/00/2, Bordetella bronchiseptica GA96-01, Bordetella bronchiseptica F2, Bordetella bronchiseptica F4563, Bordetella hinzii F-1, Bordetella bronchiseptica E014, Bordetella bronchiseptica E013, Bordetella bronchiseptica E012, Bordetella bronchiseptica E010, Bordetella bronchiseptica D993, Bordetella bronchiseptica D989, Bordetella bronchiseptica CARE970018BB, Bordetella bronchiseptica D756, Bordetella bronchiseptica CA90 BB1334, Bordetella bronchiseptica C4, Bordetella bronchiseptica B18-5 (C3), Bordetella bronchiseptica A1-7, Bordetella bronchiseptica 980, Bordetella bronchiseptica 7E71, Bordetella bronchiseptica 3E44, Bordetella bronchiseptica 345, Bordetella bronchiseptica 00-P-2796, Bordetella bronchiseptica 00-P-2730, Bordetella bronchiseptica ISU-CA 90 BB 02, Bordetella bronchiseptica MO211, Bordetella bronchiseptica 980-2, Bordetella bronchiseptica OSU-O54, Bordetella bronchiseptica Bbr77, Bordetella bronchiseptica 1289, Bordetella bronchiseptica MO149, Bordetella bronchiseptica RB50, Bordetella parapertussis 12822, Bordetella parapertussis Bacteria UP000007564, UP000064190, UP000028136, UP000027181, UP000027133, UP000027277, UP000027102, UP000027201, UP000027146, UP000027040, UP000027077, UP000027261, UP000027228, UP000027166, UP000027348, UP000027264, UP000027260, UP000027325, UP000027117, UP000027011, UP000027221, UP000027141, UP000027095, UP000027039, UP000027050, UP000027074, UP000027253, UP000027313, UP000027150, UP000027103, UP000027267, UP000027229, UP000027112, UP000027149, UP000027071, UP000027250, UP000027163, UP000027342, UP000027312, UP000027063, UP000027081, UP000027019, UP000027025, UP000027017, UP000027119, UP000025652, UP000025777, UP000025463, UP000026036, UP000025756, UP000025971, UP000025404, UP000009318, UP000026640, UP000026564, UP000009317, UP000009313, UP000008036, UP000001027, UP000001421, UP000064286 489904012, 412340406, 673490269, 649799338, 633975676, 633972414, 633968437, 633592227, 633587342, 633584440, 633572416, 633568439, 633568290, 633560373, 633552214, 633548351, 633543983, 633543803, 633531888, 633530352, 633523549, 633521917, 633513503, 633512564, 633502357, 633496833, 633496547, 633488004, 633487963, 633464801, 633450797, 633445485, 633441813, 633438447, 633433381, 633427204, 633425413, 633417727, 633410585, 633400274, 633397899, 633395165, 633393869, 633383099, 633375815, 633373672, 627902148, 627896919, 627893408, 627884113, 627874139, 627869138, 620715946, 620713123, 620701340, 620693659, 410589004, 410568580, 410563554, 408770240, 408445397, 47606138, 47606134, 33575339, 33565091 KFJ56705.1, KDS81044.1, KDD94079.1, KDD90881.1, KDD86965.1, KDD63184.1, KDD58546.1, KDD55812.1, KDD44229.1, KDD40391.1, KDD40249.1, KDD32617.1, KDD24740.1, KDD21000.1, KDD16786.1, KDD16608.1, KDD04991.1, KDD03497.1, KDC96887.1, KDC95288.1, KDC87097.1, KDC86187.1, KDC76330.1, KDC71070.1, KDC70794.1, KDC62935.1, KDC62896.1, KDC46993.1, KDC34048.1, KDC29044.1, KDC25573.1, KDC22420.1, KDC17548.1, KDC11673.1, KDC09966.1, KDC02689.1, KDB96045.1, KDB86177.1, KDB83914.1, KDB81265.1, KDB80049.1, KDB69801.1, KDB62876.1, KDB60841.1, KCV56892.1, KCV51980.1, KCV48683.1, KCV40161.1, KCV31299.1, KCV26993.1, KAK74892.1, KAK72164.1, KAK60716.1, KAK53728.1 WP_003807441.1, YP_006969161.1 Q7WQM6, Q7W1Q0 THIC_BORBR, THIC_BORPA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 502059, 507132 fig|1208657.3.peg.304, fig|1208658.3.peg.291, fig|1208665.3.peg.621, fig|257311.1.peg.292, fig|257310.1.peg.300, fig|568707.3.peg.3209, fig|1208659.3.peg.2318 636 637 yes 1889331 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 470, 1310616 Acinetobacter baumannii, Acinetobacter baumannii 400834 Bacteria UP000028632, UP000021711 691042867, 587901324 EXB89600.1 WP_031992866.1 118 118 no 1889332 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 910039 candidate division OP8 bacterium SCGC AAA252-K06 Bacteria 551130670 WP_022809290.1 247 247 no 1889333 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1298607 Psychrobacter sp. JCM 18902 Bacteria UP000019502 589903414 538 570 no 1889334 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1075768 Janthinobacterium sp. CG3 Bacteria 516490885 WP_017879329.1 635 637 yes 1889335 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 861360 Arthrobacter arilaitensis Re117 Bacteria UP000006878 307745645 fig|861360.3.peg.2556 572 580 yes 1889336 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2162, 1204725 Methanobacterium formicicum, Methanobacterium formicicum DSM 3637 Archaea UP000062768, UP000007360 490129249, 407816513 EKF87075.1 WP_004029653.1 K2RWC1 K2RWC1_METFO 432 432 yes 1889337 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28184, 1049986, 1088542, 1088541, 996804, 1001589 Leptospira weilii, Leptospira weilii str. Ecochallenge, Leptospira weilii str. UI 13098, Leptospira weilii str. LNT 1234, Leptospira weilii str. 2006001855, Leptospira weilii str. 2006001853 Bacteria UP000012249, UP000012118, UP000012098, UP000012101, UP000001338 488692023, 476391734, 464298102, 464236090, 464136836, 410780542 EMY15687.1, EMN92488.1, EMN44317.1, EMM74111.1, EKR65129.1 WP_002616171.1 487 487 yes 1889338 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 195253 Synechococcus sp. PCC 6312 Bacteria UP000010379 504937757, 427377364 AFY61316.1 WP_015124859.1 fig|195253.3.peg.2248 460 461 yes 1889339 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 361575, 930171 Arthrobacter phenanthrenivorans, Arthrobacter phenanthrenivorans Sphe3 Bacteria UP000031196, UP000008639 503366743, 323469805 ADX73490.1 WP_013601404.1 fig|930171.3.peg.2335 593 609 yes 1889340 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1187851 Rhodovulum sp. PH10 Bacteria UP000002930 495658102, 402501761 EJW13405.1 WP_008382681.1 fig|1187851.3.peg.337 617 626 yes 1889341 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 1357297 Serratia marcescens, Serratia marcescens EGD-HP20 Bacteria UP000055021, UP000016500 545149873, 542024565 ERH70226.1 WP_021505239.1 632 647 yes 1889342 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2335, 1157948, 1157949 Thermotoga sp. 2812B, Thermotoga sp. EMP Bacteria UP000030637, UP000006349 495468247, 728864513, 402812018 AIY85693.1, EJX26498.1 WP_008192937.1 fig|1157949.3.peg.417 424 424 yes 1889343 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 795666 Ralstonia sp. PBA Bacteria UP000004277 497206605, 392717729 EIZ05289.1 WP_009520867.1 fig|795666.3.peg.127 628 633 yes 1889344 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1196829, 1196830 Salmonella enterica, Salmonella enterica subsp. enterica serovar Nchanga str. CFSAN001091, Salmonella enterica subsp. enterica serovar Nchanga str. CFSAN001092 Bacteria UP000054489, UP000017608, UP000017547 555268944, 554406352, 554402429 ESJ35806.1, ESJ32477.1 WP_023250107.1 626 631 yes 1889345 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 408672 Nocardioidaceae bacterium Broad-1 Bacteria UP000003498 495634425, 325951241 EGD43282.1 WP_008359004.1 558 562 yes 1889346 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 667019 Curvibacter putative symbiont of Hydra magnipapillata Bacteria 260222378 279 292 no 1889347 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1035197 Prevotella sp. oral taxon 473 str. F0040 Bacteria UP000010460 429146545 EKX89597.1 fig|1035197.3.peg.1281 614 624 yes 1889348 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106654, 1217670 Acinetobacter genomosp. 13TU, Acinetobacter nosocomialis NIPH 2119 Bacteria UP000051466, UP000013145 490848861, 479896942 ENU46585.1 WP_004710924.1 fig|1217670.3.peg.2587 621 625 yes 1889349 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 57705, 485914 Halomicrobium mukohataei, Halomicrobium mukohataei DSM 12286 Archaea UP000001746 506243476, 257388343, 257170650 ACV48409.1 WP_015763251.1, YP_003178116.1 C7NXH5 C7NXH5_HALMD 7451832 fig|485914.4.peg.1553 463 475 yes 1889350 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 164546 Cupriavidus taiwanensis Bacteria 516629887 WP_018004674.1 624 626 yes 1889351 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 77133 uncultured bacterium Environmental samples UP000041370 406939875 EKD72808.1 520 521 yes 1889352 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 1659718, 1619250, 550, 1329833, 1329829, 1329826 Enterobacter sp. GN02825, Enterobacter sp. 44593, Enterobacter cloacae, Enterobacter sp. MGH 37, Enterobacter sp. MGH 25, Enterobacter sp. MGH 22 Bacteria UP000036222, UP000033465, UP000036177, UP000020521, UP000017278, UP000017407 556480186, 829272314, 770950627, 768613735, 578280292, 555177694, 555177368 KLP70923.1, KJL51042.1, KJI46907.1, EUM40124.1, ESN20135.1, ESN19954.1 WP_023331766.1 626 631 yes 1889353 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 1365661 Campylobacter jejuni, Campylobacter jejuni K1 Bacteria UP000065538, UP000024636 695517726, 631617586 KDA33470.1 WP_032589549.1 430 430 yes 1889354 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 215689 Erwinia sp. Ejp617 Bacteria UP000006865 504355883, 310766087 ADP11037.1 WP_014542985.1 fig|215689.3.peg.1459 631 644 yes 1889355 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 452 483 yes 1889356 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 75379 Thiomonas intermedia K12 Bacteria UP000002185 295795858 ADG30648.1 fig|75379.3.peg.1795 624 669 yes 1889357 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1235990 Halyomorpha halys symbiont Bacteria UP000060036 806963120, 549073074 AKC32319.1 612 616 yes 1889358 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1564, 696281 Desulfotomaculum ruminis, Desulfotomaculum ruminis DSM 2154 Bacteria UP000009234 503606139, 334090093 AEG58433.1 WP_013840215.1 fig|696281.4.peg.139 431 432 yes 1889359 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1097667 Patulibacter sp. I11 Bacteria UP000005143 494845200, 365817286 EHN12261.1 WP_007571300.1 fig|1097667.3.peg.860 429 433 yes 1889360 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287277 Mesorhizobium sp. LNJC399B00 Bacteria UP000020135 563530854, 563074369 ESX99143.1 WP_023737078.1 596 611 yes 1889361 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28035, 904354 Staphylococcus lugdunensis, Staphylococcus lugdunensis VCU150 Bacteria UP000057304, UP000025468 739690666, 620696648 KAK56113.1 WP_037545212.1 578 578 yes 1889362 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 442694, 925776 Xanthomonas perforans, Xanthomonas perforans 91-118 Bacteria UP000035394, UP000004638 495849134, 821987584, 821984253, 821980903, 821976270, 821973594, 821968795, 821966162, 821959681, 821954949, 821950186, 821944229, 821941041, 821936676, 821933494, 821931405, 821925564, 821920052, 821917631, 821914902, 821901590, 821900435, 821897374, 821896873, 821886840, 821882146, 821880147, 821871469, 821870502, 821866573, 821858987, 821857659, 821856548, 325542985 KLD36328.1, KLD33070.1, KLD29958.1, KLD25538.1, KLD23020.1, KLD18316.1, KLD15708.1, KLD09377.1, KLD04705.1, KLD00002.1, KLC94217.1, KLC91065.1, KLC86786.1, KLC83739.1, KLC81688.1, KLC75937.1, KLC70552.1, KLC68196.1, KLC65528.1, KLC52495.1, KLC51346.1, KLC48308.1, KLC47811.1, KLC37992.1, KLC33337.1, KLC31356.1, KLC22872.1, KLC21913.1, KLC18015.1, KLC10616.1, KLC09299.1, KLC08198.1, EGD14434.1 WP_008573713.1 624 625 yes 1889363 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 885581, 646529 Desulfosporosinus acidophilus, Desulfosporosinus acidophilus SJ4 Bacteria UP000002892 504640327, 391355732 AFM41431.1 WP_014827429.1 423 423 yes 1889364 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 687 Vibrio gazogenes Bacteria 543169357 WP_021021264.1 654 660 yes 1889365 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 709797 Bradyrhizobiaceae bacterium SG-6C Bacteria UP000003148 497423039, 338231152 EGP06292.1 WP_009737237.1 634 643 yes 1889366 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 1339276 Bacteroides fragilis, Bacteroides fragilis str. DS-208 Bacteria UP000036847, UP000020414 695529273, 596024594 EXZ05279.1 WP_032594227.1 564 564 yes 1889367 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1214915 Mycobacterium smegmatis MKD8 Bacteria UP000011200 440630497 ELQ92268.1 391 432 no 1889368 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1400168 Klebsiella pneumoniae, Klebsiella pneumoniae BIDMC 52 Bacteria UP000036212, UP000023147 694069658, 583522979 EWD86548.1 WP_032415969.1 626 631 yes 1889369 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 667632 Burkholderia sp. JPY347 Bacteria 517250192 WP_018439010.1 642 643 yes 1889370 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 72174 Citromicrobium bathyomarinum Bacteria 497922248 WP_010236404.1 624 629 yes 1889371 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 60893, 880072 Desulfobacca acetoxidans, Desulfobacca acetoxidans DSM 11109 Bacteria UP000000483 503472961, 328454684 AEB10513.1 WP_013707622.1 fig|880072.3.peg.2880 424 424 yes 1889372 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1229484 alpha proteobacterium LLX12A Bacteria 516069416 WP_017499999.1 624 631 yes 1889373 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 238, 1216967 Elizabethkingia meningoseptica, Elizabethkingia meningoseptica NBRC 12535 Bacteria UP000064940, UP000014120 510824801, 507153026 EOR31173.1 WP_016197972.1 fig|1216967.5.peg.584 602 602 yes 1889374 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 101571 Burkholderia ubonensis Bacteria UP000066652 497778572 WP_010092756.1 642 643 yes 1889375 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1409786, 1314835, 1235805 Escherichia coli, Escherichia coli K02, Escherichia coli MP1, Escherichia coli SWW33 Bacteria UP000036210, UP000020359, UP000023390, UP000012503 487680468, 601461226, 587644087, 476632527 EYT03484.1, EWY51096.1, EMZ39051.1 WP_001765329.1 fig|1235805.3.peg.3966 626 631 yes 1889376 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43595, 1293054 Halanaerobium saccharolyticum, Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643 Bacteria UP000012063 491632425, 460787438 WP_005489961.1 fig|1293054.3.peg.2245 428 428 yes 1889377 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 177400 Anaerophaga thermohalophila Bacteria 515146864 WP_016775544.1 426 426 yes 1889378 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717, 1450523, 1450522, 1206107, 698971, 698969, 257309 Corynebacterium diphtheriae, Corynebacterium diphtheriae bv. gravis str. ISS 4749, Corynebacterium diphtheriae bv. gravis str. ISS 4746, Corynebacterium diphtheriae str. Aberdeen, Corynebacterium diphtheriae VA01, Corynebacterium diphtheriae HC03, Corynebacterium diphtheriae NCTC 13129 Bacteria UP000033584, UP000036598, UP000035560, UP000016138, UP000007155, UP000007159, UP000002198 499236421, 827488209, 827482224, 803298092, 535920777, 372118561, 372111701, 47606072, 38198929 KLN43156.1, KLN37268.1, KKA81935.1, ERA51269.1, AEX82295.1, AEX77760.1 WP_010933961.1 P61424 THIC_CORDI Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 519714 fig|698971.3.peg.29, fig|698969.3.peg.33, fig|257309.1.peg.29 592 599 yes 1889379 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 595 631 yes 1889380 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 837, 1227270 Porphyromonas gingivalis, Porphyromonas gingivalis F0569 Bacteria UP000028798, UP000016655 545425884, 543956047 ERJ66348.1 WP_021664399.1 587 587 yes 1889381 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 54120, 679926 Methanoplanus petrolearius, Methanoplanus petrolearius DSM 11571 Archaea UP000006565 503093451, 307155717 ADN35097.1 WP_013328276.1 E1RFU5 E1RFU5_METP4 414 422 no 1889382 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1095674 Neisseria meningitidis, Neisseria meningitidis 61103 Bacteria UP000050419, UP000010762 488179208, 432257253 ELL12556.1 WP_002250416.1 fig|1095674.3.peg.2555 625 633 yes 1889383 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 431596 Paenibacillus sp. DCY16 Bacteria 518366604 WP_019536811.1 586 586 yes 1889384 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626933, 742817 Odoribacter laneus, Odoribacter laneus YIT 12061 Bacteria UP000004892 496427157, 373227017 EHP49338.1 WP_009136004.1 fig|742817.3.peg.911 583 584 yes 1889385 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262917 Prevotella sp. CAG:1031 Environmental samples UP000018183 512184317, 511626291 WP_016411007.1 567 568 yes 1889386 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 816, 702447, 469588, 556258 Bacteroides xylanisolvens SD CC 1b, Bacteroides sp. 2_1_22, Bacteroides sp. D1 Bacteria UP000004862, UP000005775, UP000003361 495292300, 294445464, 262355151, 229445351, 584446140 EFG14119.1, EEZ04242.1, EEO51142.1 WP_008017054.1 fig|556258.5.peg.2790, fig|702447.3.peg.1576, fig|469588.3.peg.1945 565 565 yes 1889387 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2160, 1379702, 1641383 Methanobacterium sp. MB1, Methanobacterium sp. 42_16 Archaea UP000017867, UP000054221 566004138, 557945604 WP_023991248.1 A0A101HCG9, U6E9J1 A0A101HCG9_9EURY, U6E9J1_9EURY 432 432 yes 1889388 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2322, 644295 Methanohalobium evestigatum, Methanohalobium evestigatum Z-7303 Archaea UP000000391 502960535, 298675992, 298288980 ADI74946.1 WP_013195511.1, YP_003727742.1 D7EAE7 D7EAE7_METEZ 419 426 yes 1889389 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262913 Parabacteroides sp. CAG:409 Environmental samples UP000018199 548237743, 524760551 WP_022456031.1 564 564 yes 1889390 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144330 Pseudomonas sp. GM48 Bacteria UP000007293 495266790, 398162459 EJM50653.1 WP_007991545.1 fig|1144330.3.peg.5103 628 629 yes 1889391 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 208962, 1440052 Escherichia albertii, Escherichia albertii KF1 Bacteria UP000066054, UP000018871 643604306, 569537493 AHE59800.1 WP_025237912.1 626 631 yes 1889392 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053191 Bacillus cereus, Bacillus cereus BAG5X2-1 Bacteria UP000036076, UP000006611 446737193, 859503185, 401133852 KMP27419.1, EJQ41475.1 WP_000814449.1 fig|1053191.3.peg.5194 586 586 yes 1889393 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053179 Bacillus cereus, Bacillus cereus BAG2X1-1 Bacteria UP000036076, UP000006980 446737190, 401657366 EJS74876.1 WP_000814446.1 fig|1053179.3.peg.273 586 586 yes 1889394 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1053169, 1053171 Bacillus cereus BAG1O-3, Bacillus cereus BAG1X1-2 Bacteria UP000014549, UP000006958 446737196, 513461959, 401631597 EPF10096.1, EJS49392.1 WP_000814452.1 fig|1053169.3.peg.4281, fig|1053171.3.peg.4518 586 586 yes 1889395 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217704 Acinetobacter sp. NIPH 284 Bacteria UP000018441 491305109, 480142204 ENW79371.1 WP_005163112.1 fig|1217704.3.peg.2795 626 631 yes 1889396 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265, 1341157 Ruminococcus flavefaciens, Ruminococcus flavefaciens 007c Bacteria UP000019365 739437839, 585220047 EWM54420.1 WP_037297879.1 437 437 yes 1889397 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053207 Bacillus cereus, Bacillus cereus HuB1-1 Bacteria UP000036076, UP000002927 446737195, 402454124 EJV85917.1 WP_000814451.1 fig|1053207.3.peg.516 586 586 yes 1889398 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 519, 1208660 Bordetella parapertussis, Bordetella parapertussis Bpp5 Bacteria UP000064286, UP000008035 504851662, 410471095, 408441205 WP_015038764.1, YP_006894376.1 636 637 yes 1889399 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1069617, 1069608 Neisseria meningitidis, Neisseria meningitidis 80179, Neisseria meningitidis 93003 Bacteria UP000050419, UP000005243, UP000002929 488162014, 402333185, 402315126 EJU68496.1, EJU50692.1 WP_002233222.1 fig|1069608.3.peg.2681, fig|1069617.3.peg.2792 625 633 yes 1889400 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1196322 Clostridium sp. Maddingley MBC34-26 Bacteria UP000001325 495697325, 410602068 EKQ56562.1 WP_008421904.1 fig|1196322.3.peg.1868 436 436 yes 1889401 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1236481 Bacillus stratosphericus LAMA 585 Bacteria UP000012071 460148033 EMI12440.1 fig|1236481.3.peg.3582 595 641 yes 1889402 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 232270 Alicyclobacillus pohliae Bacteria 516852573 WP_018131143.1 593 593 yes 1889403 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158155 Thioalkalivibrio sp. AKL7 Bacteria 518442028 WP_019612235.1 627 629 yes 1889404 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2426 Teredinibacter turnerae Bacteria 517088080 WP_018276898.1 638 639 yes 1889405 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 139208, 743718 Isoptericola variabilis, Isoptericola variabilis 225 Bacteria UP000009236 503603726, 334106518 AEG43408.1 WP_013837802.1 fig|743718.4.peg.606 572 575 yes 1889406 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 1350472, 1161904, 1161745 Bifidobacterium longum, Bifidobacterium longum subsp. longum 7-1B, Bifidobacterium longum subsp. longum 35B, Bifidobacterium longum subsp. longum 2-2B Bacteria UP000028505, UP000028383, UP000004446, UP000005929 494117146, 665776187, 386411584, 386408581 KEY26013.1, EIJ26303.1, EIJ23490.1 WP_007056927.1 fig|1161745.3.peg.1680, fig|1161904.3.peg.573 643 917 yes 1889407 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1413, 649639 Bacillus cellulosilyticus, Bacillus cellulosilyticus DSM 2522 Bacteria UP000001401 503255574, 315475301 ADU31904.1 WP_013490235.1 fig|649639.3.peg.3993 597 597 yes 1889408 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 675809 Vibrio cholerae, Vibrio cholerae CT 5369-93 Bacteria UP000028983, UP000003385 487841630, 262032099 EEY50673.1 WP_001915096.1 639 645 yes 1889409 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1172180 Streptomyces sp. 351MFTsu5.1 Bacteria 518978236 WP_020134111.1 601 611 yes 1889410 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1718, 1198672, 1232383, 1232381, 1075088 Corynebacterium glutamicum, Corynebacterium glutamicum Z188, Corynebacterium glutamicum SCgG2, Corynebacterium glutamicum SCgG1, Corynebacterium glutamicum S9114 Bacteria UP000031556, UP000014845, UP000014221, UP000014220, UP000004086 489955566, 519799263, 509089825, 509086801, 344043489 EPP40782.1, AGN22069.1, AGN19046.1, EGV39182.1 WP_003858873.1 fig|1075088.3.peg.2977, fig|1232381.3.peg.1499, fig|1232383.3.peg.1503 586 587 yes 1889411 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1229487 Flavobacterium sp. WG21 Bacteria 516067372 WP_017497955.1 607 607 yes 1889412 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29511, 1218599 Leptospira wolbachii, Leptospira wolbachii serovar Codice str. CDC Bacteria UP000013984 505587919, 501484417 EOQ97759.1 WP_015680449.1 502 505 yes 1889413 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 399 401 no 1889414 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 742725 Alistipes indistinctus YIT 12060 Bacteria UP000006008 353348276 EHB92548.1 fig|742725.3.peg.803 507 508 yes 1889415 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1085029 halophilic archaeon J07HB67 Archaea 541203373 ERH11353.1 U1QVK1 U1QVK1_9EURY 415 441 yes 1889416 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 188626 Dermacoccus sp. Ellin185 Bacteria UP000003057 308432915 EFP56823.1 599 621 yes 1889417 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 930773 Salmonella enterica, Salmonella enterica subsp. enterica serovar Senftenberg str. ATCC 8400 Bacteria UP000054489, UP000017273 554958700, 554091538 ESF33502.1 WP_023203718.1 626 631 yes 1889418 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1123045 Ponticaulis koreensis Bacteria 550944907 WP_022693309.1 645 653 yes 1889419 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1412559 Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120677 Bacteria UP000068391 603402725 AHS25362.1 626 631 yes 1889420 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1155715 Streptomyces sp. CcalMP-8W Bacteria 517301056 WP_018489874.1 588 601 yes 1889421 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 303, 1268068, 1144337 Pseudomonas putida, Pseudomonas sp. G5(2012), Pseudomonas sp. GM78 Bacteria UP000054813, UP000014290, UP000007302 495338802, 820907048, 665416940, 510310538, 398235595 KKX58261.1, KEX89787.1, EPA95786.1, EJN21411.1 WP_008063536.1 fig|1268068.3.peg.3590, fig|1144337.3.peg.5057 628 629 yes 1889422 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1400165 Klebsiella pneumoniae, Klebsiella pneumoniae BIDMC 47 Bacteria UP000036212, UP000023159 694074950, 583543714, 641641393 EWE07123.1 WP_032420776.1 fig|426117.7.peg.1145, fig|398261.3.peg.4677 626 631 yes 1889423 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358, 1082932 Agrobacterium tumefaciens, Agrobacterium tumefaciens CCNWGS0286 Bacteria UP000064781, UP000003554 489600394, 355537101 EHH06361.1 WP_003504836.1 fig|1082932.3.peg.1879 600 607 yes 1889424 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29291, 259564 Methanococcoides burtonii, Methanococcoides burtonii DSM 6242 Archaea UP000001979 499818092, 91711741 ABE51668.1 WP_011498826.1 Q12Y08 Q12Y08_METBU fig|259564.8.peg.660 429 429 yes 1889425 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 519085393 WP_020241268.1 302 304 yes 1889426 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1173025 Geitlerinema sp. PCC 7407 Bacteria UP000010383 427986449 AFY67593.1 fig|1173025.3.peg.3491 459 461 yes 1889427 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 249058, 1108044 Gordonia otitidis, Gordonia otitidis NBRC 100426 Bacteria UP000005038 494444070, 377524532 WP_007237341.1 fig|1108044.3.peg.869 549 561 yes 1889428 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 184914, 1144275 Corallococcus coralloides, Corallococcus coralloides DSM 2259 Bacteria UP000007587 504209411, 380734471 AFE10473.1 WP_014396513.1 fig|1144275.3.peg.3769 620 623 yes 1889429 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1267534 Acidobacteriaceae bacterium KBS 89 Bacteria 522206605 WP_020714072.1 479 489 yes 1889430 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1006005, 1006006 Metallosphaera cuprina, Metallosphaera cuprina Ar-4 Archaea UP000007812 503503157, 329567215 AEB95320.1 WP_013737818.1 F4G3F0 F4G3F0_METCR 433 433 yes 1889431 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1400022 Escherichia coli, Escherichia coli D6-113.11 Bacteria UP000036210, UP000028871 693053910, 665439505, 633881771 WP_032222272.1 626 631 yes 1889432 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 380, 1185652 Sinorhizobium fredii, Sinorhizobium fredii USDA 257 Bacteria UP000006180 504575942, 390127493 AFL50874.1 WP_014763044.1 fig|1185652.3.peg.2370 598 610 yes 1889433 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106649, 1217656 Acinetobacter guillouiae, Acinetobacter guillouiae NIPH 991 Bacteria UP000013148 490954754, 479974837 ENV18964.1 WP_004816569.1 fig|1217656.3.peg.54 626 631 yes 1889434 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33059, 637389 Acidithiobacillus caldus, Acidithiobacillus caldus ATCC 51756 Bacteria UP000005522 491006697, 640842097 AIA55982.1 WP_004868416.1 fig|637389.3.peg.299 619 620 yes 1889435 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 501497 Thermodesulfatator sp. AT1325 Bacteria 551229123 WP_022852924.1 431 435 yes 1889436 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 93217, 1380774 Pandoraea sp. RB-44 Bacteria UP000018548 564965962, 564127321 AHB74824.1 WP_023872078.1 637 638 yes 1889437 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263045 Bacteroides finegoldii CAG:203 Environmental samples UP000018058 547869056, 524513845 WP_022275285.1 562 562 yes 1889438 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262898 Faecalibacterium sp. CAG:82 Environmental samples UP000018070 547849302, 524488447 WP_022256440.1 435 436 yes 1889439 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1003237 Azospirillum amazonense Y2 Bacteria UP000018435 346917773 EGY00019.1 fig|1003237.3.peg.4479 607 617 yes 1889440 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 588 880 yes 1889441 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262825 Clostridium sp. CAG:590 Environmental samples UP000017939 546685602, 524003488 WP_021884946.1 434 434 yes 1889442 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1047068 519095687 WP_020251562.1 422 422 yes 1889443 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397533 Marinobacter sp. EN3 Bacteria UP000017083 550686676 ERS10879.1 585 585 yes 1889444 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1232188 Clostridium botulinum CFSAN001628 Bacteria UP000010454 428756021 EKX78609.1 fig|1232188.3.peg.3550 96 96 no 1889445 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 712288, 861452 Fusobacterium sp. oral taxon 370, Fusobacterium sp. oral taxon 370 str. F0437 Bacteria UP000003908 496967024, 357069484 EHI79391.1 WP_009423017.1 fig|861452.3.peg.317 433 433 yes 1889446 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 891, 281689 Desulfuromonas acetoxidans, Desulfuromonas acetoxidans DSM 684 Bacteria UP000005695 492848065, 95133248 EAT14914.1 WP_006002019.1 fig|891.1.peg.557, fig|281689.4.peg.2797 435 435 yes 1889447 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 697286 Paenibacillus larvae subsp. larvae 08-100 Bacteria UP000018834 567771303 ETK28651.1 599 603 yes 1889448 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78120 Succinispira mobilis Bacteria 518718754 WP_019879460.1 431 431 yes 1889449 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 152794, 196164 Corynebacterium efficiens, Corynebacterium efficiens YS-314 Bacteria UP000002618 493821867, 259166055, 29337061 EEW50609.1 WP_006769370.1 Q8FPT3 THIC_COREF Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 300296 fig|196164.1.peg.1407, fig|196164.6.peg.1406 579 580 yes 1889450 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265470 Desulfurispora thermophila Bacteria 516757160 WP_018086732.1 418 424 yes 1889451 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 80880, 1458275 Hylemonella gracilis, Hylemonella gracilis str. Niagara R Bacteria UP000023268 737634633, 597956981 EYC50169.1 WP_035604675.1 628 637 yes 1889452 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 382, 693982 Sinorhizobium meliloti, Sinorhizobium meliloti AK83 Bacteria UP000028953, UP000008705 503616204, 334097897 AEG55907.1 WP_013850280.1 600 611 yes 1889453 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280948 Hyphomonas sp. 22II1-22F38 Bacteria UP000024547 737583198, 630776924 KCZ58434.1 WP_035554163.1 625 625 yes 1889454 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 889230 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni 1213 Bacteria UP000065538, UP000005708 489010457, 380661843 EIB77711.1 WP_002921011.1 fig|889230.3.peg.15 430 430 yes 1889455 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 1256995, 1256996, 1328431 Klebsiella oxytoca, Klebsiella oxytoca OK-1, Klebsiella oxytoca KA-2, Klebsiella oxytoca MGH 42 Bacteria UP000030350, UP000021012, UP000020027, UP000017341 556468390, 577052084, 577049638, 555135146 EUC89935.1, EUC87697.1, ESM77942.1 WP_023320146.1 626 631 yes 1889456 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28090 Acinetobacter lwoffii Bacteria 498011555 WP_010325711.1 627 630 yes 1889457 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144333 Pseudomonas sp. GM55 Bacteria UP000007268 495292174, 398189160 EJM76443.1 WP_008016928.1 fig|1144333.3.peg.1240 628 629 yes 1889458 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47917, 1332071 Serratia fonticola, Serratia fonticola AU-AP2C Bacteria UP000061771, UP000017022 546166219, 544006739 ERK05576.1 WP_021808061.1 633 647 yes 1889459 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 674, 1259812 Vibrio mimicus, Vibrio mimicus CAIM 602 Bacteria UP000053748, UP000011930 491669090, 449078672 EMB49604.1 WP_005525232.1 fig|1259812.3.peg.2543 640 646 yes 1889460 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262956 Ruminococcus sp. CAG:379 Environmental samples UP000018306 547957145, 524640585 WP_022357622.1 436 436 yes 1889461 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 376804 Bacteroides barnesiae Bacteria 517540650 WP_018710858.1 564 564 yes 1889462 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1007105 Pusillimonas sp. T7-7 Bacteria UP000008737 503507324, 330428115 AEC19449.1 WP_013741985.1 fig|1007105.3.peg.893 636 637 yes 1889463 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1354301 Clostridium sp. BL8 Bacteria UP000015873 544870794, 530689255 EQB87397.1 WP_021284153.1 437 437 yes 1889464 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413502, 693216 Cronobacter turicensis, Cronobacter turicensis z3032 Bacteria UP000002069 502535128, 260215274 WP_012814952.1 fig|413502.6.peg.294, fig|693216.3.peg.293 626 633 yes 1889465 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1288794, 1238221 Vibrio parahaemolyticus, Vibrio parahaemolyticus EN9701072, Vibrio parahaemolyticus VPTS-2009 Bacteria UP000028114, UP000032089, UP000024628 646517568, 820938361, 820930594, 778239642, 758045832, 655764908, 655673867, 589848050 KKX88486.1, KKX81044.1, KJR33652.1, KIT55077.1, KEE48461.1, KED68295.1, EXJ25121.1 WP_025548309.1 640 646 yes 1889466 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1444770 Xylella fastidiosa XfPE Bacteria UP000020406 586882902 EWS77273.1 583 585 yes 1889467 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43660, 1117320 Pseudoalteromonas undina, Pseudoalteromonas undina NCIMB 2128 Bacteria UP000016534 498076368, 540297049 ERG59955.1 WP_010390524.1 645 650 yes 1889468 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28090, 1217667 Acinetobacter lwoffii, Acinetobacter lwoffii CIP 70.31 Bacteria 491243253, 480084674 ENW23155.1 WP_005101459.1 fig|1217667.3.peg.3376 627 631 yes 1889469 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2015 Nocardiopsis prasina Bacteria 516111933 WP_017542513.1 551 555 yes 1889470 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78355 Streptomyces somaliensis Bacteria 498153712 WP_010467868.1 590 592 yes 1889471 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553191, 871562 Bifidobacterium dentium JCVIHMP022, Bifidobacterium dentium ATCC 27679 Bacteria UP000003457, UP000003323 308221245, 304554370 EFO77548.1, EFM42278.1 630 855 yes 1889472 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262747 Bacteroides sp. CAG:702 Environmental samples UP000017962 547308917, 524202052 WP_022040883.1 563 563 yes 1889473 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 270495 Fangia hongkongensis Bacteria 517111835 WP_018300653.1 616 616 yes 1889474 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1286094 Streptomyces aurantiacus JA 4570 Bacteria UP000014629 514327354 EPH40442.1 549 550 yes 1889475 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 748658 Thioalkalivibrio sp. ASLr1 Bacteria 518471287 WP_019641494.1 626 629 yes 1889476 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314262 Roseobacter sp. MED193 Bacteria UP000005943 497494868, 85825326 EAQ45525.1 WP_009809066.1 fig|314262.3.peg.4050 598 608 yes 1889477 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 427923, 589865 Desulfurivibrio alkaliphilus, Desulfurivibrio alkaliphilus AHT2 Bacteria UP000001508 502928842, 296925481 ADH86291.1 WP_013163818.1 fig|589865.4.peg.1637 422 435 yes 1889478 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 52133 Acinetobacter venetianus Bacteria 518215649 WP_019385857.1 626 631 yes 1889479 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42838, 429009 Ammonifex degensii, Ammonifex degensii KC4 Bacteria UP000002620 506218420, 260864211 ACX51317.1 WP_015738195.1 fig|429009.3.peg.144 433 434 yes 1889480 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 655816, 703612 Bacillus subtilis subsp. spizizenii str. W23, Bacillus subtilis subsp. spizizenii ATCC 6633 Bacteria UP000002233, UP000003914 305411822, 296150219 ADM36941.1, EFG91107.1 fig|703612.3.peg.2846, fig|655816.3.peg.898 591 591 yes 1889481 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 629268 Pseudomonas syringae pv. aptata str. DSM 50252 Bacteria UP000005484 330983327 EGH81430.1 177 177 no 1889482 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 453851 Henriciella marina Bacteria 516888009 WP_018149110.1 646 646 yes 1889483 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263086 Megamonas funiformis CAG:377 Environmental samples UP000018249 547819061, 524451406 WP_022227730.1 433 434 yes 1889484 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 453415 uncultured Aquificae bacterium Environmental samples 374850324 452 455 yes 1889485 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116194 Escherichia coli, Escherichia coli P0305260.5 Bacteria UP000036210, UP000012213 487376483, 477340080 ENG09284.1 WP_001649571.1 fig|1116194.3.peg.4235 626 631 yes 1889486 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380763 Paenibacillus sp. Br Bacteria UP000054119 738773895, 595753107 EXX87406.1 WP_036667044.1 586 586 yes 1889487 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 756892, 1341679, 1217660 Acinetobacter sp. A648, Acinetobacter indicus CIP 110367, Acinetobacter indicus ANC 4215 Bacteria UP000053942, UP000018415, UP000018443 514971407, 554742313, 514091167 ESK47386.1, EPF71270.1 WP_016659693.1 fig|1217660.3.peg.2284 627 631 yes 1889488 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281194 Escherichia coli, Escherichia coli UMEA 3151-1 Bacteria UP000036210, UP000016354 545269208, 536014310 ERB13529.1 WP_021559615.1 626 631 yes 1889489 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 662, 314291 Vibrio splendidus 12B01 Bacteria UP000005350 490874663, 84375737 EAP92633.1 WP_004736664.1 fig|617148.3.peg.2270, fig|617145.3.peg.4347, fig|617147.3.peg.1410, fig|314291.3.peg.2030, fig|1136162.3.peg.868, fig|530557.3.peg.3838 640 649 yes 1889490 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1419876 Blastomonas sp. CACIA14H2 Bacteria UP000019523 564013482, 563281711 ESZ86285.1 WP_023838883.1 625 634 yes 1889491 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 607712, 1032488 Neisseria shayeganii, Neisseria shayeganii 871 Bacteria UP000003019 496411160, 348012508 EGY51453.1 WP_009120024.1 fig|1032488.3.peg.2208 621 624 yes 1889492 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1223307 Streptomyces sp. PVA 94-07 Bacteria UP000017765 557416181, 556922660 ESQ05271.1 WP_023418274.1 595 597 yes 1889493 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 511 513 yes 1889494 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 611 616 yes 1889495 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29581 Janthinobacterium lividum Bacteria UP000023814 498079186 WP_010393342.1 636 637 yes 1889496 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263021 Firmicutes bacterium CAG:41 Environmental samples UP000018139 547821272, 524454958 WP_022229750.1 434 434 yes 1889497 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1159870 Bordetella sp. FB-8 Bacteria 518779861 WP_019937150.1 636 637 yes 1889498 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 518892169 WP_020048044.1 598 605 yes 1889499 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 673519 Vibrio harveyi 1DA3 Bacteria UP000004396 269831294 EEZ85445.1 641 732 yes 1889500 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444076, 1444186, 1444074, 1444234, 1444253, 1444278, 1444259, 1444192 Escherichia coli, Escherichia coli 8-415-05_S1_C2, Escherichia coli 5-172-05_S3_C3, Escherichia coli 2-474-04_S1_C2, Escherichia coli 2-222-05_S4_C2, Escherichia coli 3-475-03_S4_C2, Escherichia coli 3-105-05_S4_C3, Escherichia coli 2-011-08_S4_C3, Escherichia coli 1-392-07_S3_C3 Bacteria UP000036210, UP000028017, UP000027996, UP000028004, UP000027718, UP000027942, UP000027688, UP000027836, UP000023804 692985580, 660317194, 660050398, 652190727, 652077528, 650134129, 650029144, 649987924, 611062860 KEO05179.1, KEL46615.1, KDY99781.1, KDX93574.1, KDU53850.1, KDT52635.1, KDT13154.1, EZJ65555.1 WP_032174862.1 626 631 yes 1889501 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2702 Gardnerella vaginalis Bacteria UP000037770 497679472 WP_009993656.1 220 465 no 1889502 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106649, 1330038, 1217655 Acinetobacter guillouiae, Acinetobacter guillouiae MSP4-18, Acinetobacter guillouiae CIP 63.46 Bacteria UP000014597, UP000013121 490863269, 514266369, 479907575 EPH38281.1, ENU56567.1 WP_004725307.1 fig|1217655.3.peg.4229 626 631 yes 1889503 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317, 1205752 Pseudomonas syringae, Pseudomonas syringae BRIP39023 Bacteria UP000028642, UP000011212 489527211, 440376747 ELQ13410.1 WP_003431959.1 fig|1205752.4.peg.1187 627 629 yes 1889504 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1049933 Leptospira interrogans str. L1207 Bacteria UP000012093 464243792 EMN50705.1 137 138 no 1889505 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1007084, 886738 Candidatus Nitrosoarchaeum limnia, Nitrosopumilaceae archaeon SFB1 Archaea UP000004348 494643333, 329138746 EGG42988.1 WP_007401277.1 F3KI31 F3KI31_9ARCH 440 440 yes 1889506 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56454, 863365 Xanthomonas hortorum, Xanthomonas hortorum pv. carotae str. M081 Bacteria UP000018527 565807835, 564590455 ETC87021.1 WP_023905023.1 624 625 yes 1889507 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 103816, 1114960 Rhodococcus pyridinivorans, Rhodococcus pyridinivorans AK37 Bacteria UP000005064 493599550, 359734660 EHK83632.1 WP_006552237.1 fig|1114960.4.peg.2317 571 585 yes 1889508 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 408, 882800 Methylobacterium extorquens, Methylobacterium extorquens DSM 13060 Bacteria UP000004382 489696905, 373565921 EHP91942.1 WP_003601061.1 fig|882800.3.peg.3116 625 630 yes 1889509 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 702444 Bacteroides ovatus SD CC 2a Bacteria UP000019383 292640948, 584443770 EFF59166.1 537 541 yes 1889510 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310825, 1310892 Acinetobacter baumannii, Acinetobacter baumannii 1064293_46, Acinetobacter baumannii 44895_8 Bacteria UP000028632, UP000027048, UP000020883 691020589, 629026767, 593853868 KCW24621.1, EXT11289.1 WP_031980416.1 621 625 yes 1889511 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 407 518936952 WP_020092827.1 622 628 yes 1889512 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 396, 1128399 Rhizobium phaseoli, Rhizobium phaseoli Ch24-10 Bacteria UP000034829 515106460, 821565301 KKZ83530.1 WP_016735570.1 601 610 yes 1889513 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 223527, 1072583 Halomonas boliviensis, Halomonas boliviensis LC1 Bacteria UP000005756 494171509, 357970855 EHJ93300.1 WP_007111236.1 631 634 yes 1889514 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 645, 1216980 Aeromonas salmonicida, Aeromonas salmonicida subsp. masoucida NBRC 13784 Bacteria UP000052231, UP000024990 755118400, 612335073 WP_042468927.1 644 668 yes 1889515 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1317122 Aquimarina sp. 22II-S11-z7 Bacteria UP000023541 736107098, 610628822 EZH74858.1 WP_034239705.1 619 619 yes 1889516 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 153233 Oceanicaulis alexandrii Bacteria 550951970 WP_022700365.1 621 630 yes 1889517 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 209882 Fusobacterium nucleatum, Fusobacterium nucleatum subsp. vincentii ATCC 49256 Bacteria UP000006454 492573605, 27886781 EAA23917.1 WP_005890869.1 fig|209882.4.peg.1425 433 433 yes 1889518 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1771, 1150599 Mycobacterium phlei, Mycobacterium phlei RIVM601174 Bacteria UP000004033 489983986, 383337604 EID15979.1 WP_003887051.1 fig|1150599.3.peg.1151 528 529 yes 1889519 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1321783, 1321784 Peptostreptococcaceae bacterium oral taxon 113, Peptostreptococcaceae bacterium oral taxon 113 str. W5053 Bacteria UP000016618 545437043, 543977281 ERJ81304.1 WP_021674842.1 436 437 yes 1889520 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 92003 Azoarcus toluclasticus Bacteria 517817782 WP_018987990.1 638 638 yes 1889521 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310678, 1310651, 1310647 Acinetobacter baumannii, Acinetobacter baumannii 263903-1, Acinetobacter baumannii 230853, Acinetobacter baumannii 1461402 Bacteria UP000028632, UP000054080, UP000023773, UP000023791 736664044, 630419177, 587881646, 587841471 KCX36559.1, EXB70581.1, EXB32074.1 WP_034671016.1 626 630 yes 1889522 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 283734 Staphylococcus pseudintermedius Bacteria UP000069715 519063551 WP_020219426.1 578 578 yes 1889523 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40988, 882081, 1114959 Saccharomonospora azurea, Saccharomonospora azurea NA-128, Saccharomonospora azurea SZMC 14600 Bacteria UP000004705, UP000003647 491583932, 379255210, 359738505 EHY89136.1, EHK87390.1 WP_005441500.1 fig|1114959.3.peg.2113, fig|882081.3.peg.2149 544 546 yes 1889524 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1235798 Dorea sp. 5-2 Bacteria UP000014211 510887294, 507818853 EOS75243.1 WP_016221025.1 fig|1235798.3.peg.4612 433 434 yes 1889525 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29485, 527004 Yersinia rohdei, Yersinia rohdei ATCC 43380 Bacteria UP000031914, UP000010311 490854437, 755395463, 238708994, 811540291 AJJ12701.1, EEQ01244.1 WP_004716485.1 fig|527004.3.peg.3593 654 677 yes 1889526 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1301086 Bacillus sp. GeD10 Bacteria UP000013202 493974517, 482659121 WP_006917602.1 fig|1301086.3.peg.741 586 586 yes 1889527 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1525, 1325331 Moorella thermoacetica, Moorella thermoacetica Y72 Bacteria UP000067720, UP000063718 647357441, 586909953 WP_025773025.1 420 426 yes 1889528 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1525, 1325331 Moorella thermoacetica, Moorella thermoacetica Y72 Bacteria UP000067720, UP000063718 647357443, 586909954 WP_025773026.1 432 432 yes 1889529 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1173021 cyanobacterium PCC 7702 Bacteria 515891353 WP_017321936.1 455 457 yes 1889530 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 258533 Mycobacterium cosmeticum Bacteria UP000028870 738449961, 597300560 WP_036401146.1 516 520 yes 1889531 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33889, 1229781 Brevibacterium casei, Brevibacterium casei S18 Bacteria UP000009879 496830916, 425480397 EKU47563.1 WP_009377357.1 fig|1229781.4.peg.1492 585 596 yes 1889532 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29507, 1193050 Leptospira kirschneri, Leptospira kirschneri str. H2 Bacteria UP000006336 490917744, 410006061 EKO59834.1 WP_004779627.1 fig|1193050.3.peg.3508 436 490 yes 1889533 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 160846, 1230458 Natrialba taiwanensis, Natrialba taiwanensis DSM 12281 Archaea 493880415, 445635770 ELY88937.1 WP_006826695.1 L9ZTQ6 L9ZTQ6_9EURY 455 464 yes 1889534 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 1328430 Klebsiella oxytoca, Klebsiella oxytoca MGH 41 Bacteria UP000030350, UP000021473 695834030, 838846725, 583716288 KLY28718.1, EWF78343.1 WP_032747408.1 626 631 yes 1889535 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 324057 Paenibacillus sp. JDR-2 Bacteria UP000002510 502363929, 247542392 ACS99410.1 WP_012772732.1 fig|324057.4.peg.727 586 587 yes 1889536 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1144661, 1217988 Acinetobacter sp. CIP 101934, Acinetobacter schindleri CIP 107287 Bacteria UP000018437, UP000018440 491034682, 480162472, 480000844 ENW99268.1, ENV43067.1 WP_004896364.1 fig|1217988.3.peg.3091, fig|1221311.3.peg.1284, fig|1144661.3.peg.2873 627 631 yes 1889537 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1104682 Pseudomonas syringae pv. actinidiae ICMP 18804 Bacteria UP000015681 519225995 EPN07493.1 83 83 no 1889538 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 1035817 Bifidobacterium longum, Bifidobacterium longum subsp. longum KACC 91563 Bacteria UP000028505, UP000008938 504298393, 338754179 AEI97168.1 WP_014485495.1 fig|1035817.4.peg.586 635 917 yes 1889539 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 516583387 WP_017958426.1 603 605 yes 1889540 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2711, 85681 Citrus sinensis, Citrus clementina Plants UP000027120, UP000030687 568870595, 567864760, 567864758, 567864756, 567864754, 567864752, 557526963, 557526962, 557526961, 557526960, 557526959 ESR38269.1, ESR38268.1, ESR38267.1, ESR38266.1, ESR38265.1 XP_006488485.1, XP_006425029.1, XP_006425028.1, XP_006425027.1, XP_006425026.1, XP_006425025.1 553 646 yes 1889541 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 748224 Faecalibacterium cf. prausnitzii KLE1255 Bacteria UP000006028 310623205 EFQ06644.1 446 454 yes 1889542 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36809 Mycobacterium abscessus Bacteria UP000046141 515403304 WP_016892452.1 545 546 yes 1889543 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053192 Bacillus cereus, Bacillus cereus BAG6O-1 Bacteria UP000036076, UP000003125 446737201, 402422486 EJV54724.1 WP_000814457.1 fig|1053192.3.peg.347 586 586 yes 1889544 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053249, 1053183 Bacillus cereus, Bacillus cereus VDM053, Bacillus cereus BAG3X2-1 Bacteria UP000036076, UP000014029, UP000006981 446737206, 500433829, 401109111 EOP47756.1, EJQ17039.1 WP_000814462.1 fig|1053183.3.peg.362, fig|1053249.3.peg.5935 586 586 yes 1889545 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053210 Bacillus cereus, Bacillus cereus HuB4-10 Bacteria UP000036076, UP000006990 446737204, 401168832 EJQ76084.1 WP_000814460.1 fig|1053210.3.peg.4411 586 586 yes 1889546 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 877424 rumen bacterium NK4A179 Bacteria 551040779 WP_022784429.1 445 446 yes 1889547 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1125641 Escherichia coli, Escherichia coli P0301867.2 Bacteria UP000036210, UP000012311 486163048, 476737237 ENA41815.1 WP_001526596.1 fig|1125641.3.peg.4478 626 631 yes 1889548 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1379702 Methanobacterium sp. MB1 Archaea UP000017867 566004199, 557945665 WP_023991309.1 U6EAR8 U6EAR8_9EURY 424 424 yes 1889549 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1133849 Nocardia brasiliensis ATCC 700358 Bacteria UP000006304 407311999 AFU05900.1 536 537 yes 1889550 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 256847, 313628 Lentisphaera araneosa, Lentisphaera araneosa HTCC2155 Bacteria UP000004947 494489519, 149138675 EDM27081.1 WP_007278990.1 322 322 no 1889551 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1117645 Elizabethkingia anophelis Bacteria UP000053163 737618194, 609718385, 609710771 WP_035588659.1 602 602 yes 1889552 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 452652 Kitasatospora setae KM-6054 Bacteria UP000007076 311897377 fig|452652.3.peg.3987 598 601 yes 1889553 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717, 698967, 698966 Corynebacterium diphtheriae, Corynebacterium diphtheriae HC01, Corynebacterium diphtheriae 241 Bacteria UP000033584, UP000007157, UP000007868 504067098, 372107219, 371579427 AEX73280.1, AEX43094.1 WP_014301092.1 fig|698967.3.peg.30, fig|698966.3.peg.31 592 599 yes 1889554 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 52133, 1191460 Acinetobacter venetianus, Acinetobacter venetianus RAG-1 = CIP 110063 Bacteria UP000018445 491014669, 479996489 ENV38943.1 WP_004876377.1 626 631 yes 1889555 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1310611 Acinetobacter baumannii 466760 Bacteria UP000022459 587901151 EXB89433.1 142 142 no 1889556 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573569 Francisella sp. TX077308 Bacteria UP000000490 503688840, 336446775 AEI36081.1 WP_013922916.1 fig|573569.4.peg.1154 592 592 yes 1889557 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 575565 Acinetobacter sp. SH024 Bacteria UP000004924 292827292 EFF85656.1 621 626 yes 1889558 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630, 1262467 Yersinia enterocolitica, Yersinia enterocolitica (type O:2) str. YE3094/96 Bacteria UP000029427, UP000018119 812240188, 812207010, 812140024, 802930036, 510414464 634 655 yes 1889559 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 212663 Vibrio tasmaniensis Bacteria 515665968 WP_017098568.1 640 649 yes 1889560 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1288788, 1288793, 1288797, 1288786, 1288783, 1288791, 1288796, 1288780, 1173954, 1238223, 1238194, 1238197, 1238196, 1238195, 1238224, 1238231, 745023 Vibrio parahaemolyticus, Vibrio parahaemolyticus 3631, Vibrio parahaemolyticus EN2910, Vibrio parahaemolyticus EN9901310, Vibrio parahaemolyticus 3324, Vibrio parahaemolyticus 846, Vibrio parahaemolyticus 12315, Vibrio parahaemolyticus EN9701173, Vibrio parahaemolyticus 97-10290, Vibrio parahaemolyticus O4:K12 str. K1203, Vibrio parahaemolyticus VPCR-2009, Vibrio parahaemolyticus SBR10290, Vibrio parahaemolyticus 3256, Vibrio parahaemolyticus 12310, Vibrio parahaemolyticus 10296, Vibrio parahaemolyticus VPCR-2010, Vibrio parahaemolyticus 10290, Vibrio parahaemolyticus 10329 Bacteria UP000028114, UP000032455, UP000032064, UP000032104, UP000032053, UP000032109, UP000032059, UP000032072, UP000032115, UP000028005, UP000025065, UP000021120, UP000019065, UP000018505, UP000018507, UP000016004, UP000015860, UP000005074 491639831, 821233902, 821233399, 820938810, 820912665, 807096163, 807091403, 807078004, 807076864, 778229021, 758733641, 758733539, 758726758, 758725991, 758721379, 758708573, 758705845, 758703217, 758690871, 758690470, 758689403, 758683879, 758675365, 758673488, 758019256, 758008331, 757992993, 757988160, 757984322, 757978573, 757976201, 757970853, 741246064, 738585916, 726144998, 655786560, 655780483, 655772934, 655768452, 655760449, 655756986, 655751815, 655746692, 655735773, 655733592, 655731434, 655721109, 655711944, 655646383, 655644527, 589849154, 575550248, 573516297, 562752113, 560386947, 532616111, 532376850, 328471301 KKY96649.1, KKY96174.1, KKX88930.1, KKX63719.1, KKC84934.1, KKC80267.1, KKC67038.1, KKC65983.1, KJR23613.1, KIV36136.1, KIV36041.1, KIV29391.1, KIV28302.1, KIV24106.1, KIV11550.1, KIV08858.1, KIV06274.1, KIU94152.1, KIU93759.1, KIU92702.1, KIU87280.1, KIU78859.1, KIU77007.1, KIT30850.1, KIT20785.1, KIT05619.1, KIT00895.1, KIS97114.1, KIS91489.1, KIS89150.1, KIS83886.1, KHT69799.1, KHQ89270.1, KHF15553.1, KEE68517.1, KEE62816.1, KEE55913.1, KEE51845.1, KEE44281.1, KEE41136.1, KEE36496.1, KEE31935.1, KEE22573.1, KEE20796.1, KEE18984.1, KEE09982.1, KEE01931.1, KED44241.1, KED42638.1, EXJ26175.1, ETX50446.1, ETT16088.1, ESW41844.1, ESV66128.1, EQM49739.1, EQL83545.1, EGF42200.1 WP_005497360.1 640 646 yes 1889561 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 1249634 Serratia marcescens, Serratia marcescens FGI94 Bacteria UP000055021, UP000011001 505157131, 440050735 AGB80638.1 WP_015344233.1 fig|1249634.3.peg.235 632 644 yes 1889562 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263065 Clostridium clostridioforme CAG:132 Environmental samples UP000018009 547791482, 524415874 WP_022201662.1 434 435 yes 1889563 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 542, 627343, 1194424, 622759 Zymomonas mobilis, Zymomonas mobilis subsp. mobilis CP4, Zymomonas mobilis subsp. mobilis NRRL B-12526, Zymomonas mobilis subsp. mobilis NCIMB 11163 Bacteria UP000019436, UP000019428, UP000000319 502557899, 586617664, 586608918, 559150580, 258552636 AHJ72530.1, AHJ70676.1, AHB10370.1, ACV75582.1 WP_012817461.1 fig|622759.3.peg.1143 602 604 yes 1889564 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1156937 Methylacidiphilum fumariolicum SolV Bacteria UP000004837 384525220 fig|1156937.4.peg.2577 632 640 yes 1889565 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702, 698950 Gardnerella vaginalis, Gardnerella vaginalis 284V Bacteria UP000037770, UP000004256 490214211, 388053321 EIK76312.1 WP_004112596.1 fig|698950.3.peg.466 609 881 yes 1889566 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1203559 Corynebacterium sp. KPL1818 Bacteria UP000017169 552858390, 550757977 ERS56781.1 WP_023031152.1 620 643 yes 1889567 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 196, 1507806, 1244528 Campylobacter fetus, Campylobacter fetus subsp. testudinum, Campylobacter sp. 03-427 Bacteria UP000031165, UP000031107, UP000017761 557308677, 742918663, 556853829 AJB45059.1, AGZ81306.1 WP_023384475.1 449 450 yes 1889568 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1111120 Acidaminococcus sp. BV3L6 Bacteria UP000016624 545612392, 544360227 ERL18577.1 WP_021736858.1 434 434 yes 1889569 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 330, 1182590 Pseudomonas pseudoalcaligenes, Pseudomonas pseudoalcaligenes CECT 5344 Bacteria UP000033611, UP000032841 489554565, 652790131, 582003016 WP_003459151.1 627 627 yes 1889570 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1304888 Geovibrio thiophilus L21-Ace-BES Bacteria 551223560 WP_022851081.1 425 425 yes 1889571 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 188937 Methanosarcina acetivorans C2A Archaea UP000002487 UP000002487 19914030 AAM03714.1 Q8TU14 Q8TU14_METAC fig|188937.1.peg.260 406 422 no 1889572 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 717785 Hyphomicrobium sp. MC1 Bacteria UP000000494 337758469 fig|82.3.peg.1025 611 614 yes 1889573 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 179878 Sphingomonas elodea Bacteria 498230024 WP_010544180.1 618 625 yes 1889574 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116193 Escherichia coli, Escherichia coli P0305260.4 Bacteria UP000036210, UP000012412 487374554, 477330246 ENF99839.1 WP_001647908.1 fig|1116193.3.peg.4237 626 631 yes 1889575 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 519089267 WP_020245142.1 626 631 yes 1889576 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 254408 Singularimonas variicoloris Bacteria 522140071 WP_020651280.1 626 629 yes 1889577 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1155739, 489825 Moorea producens, Lyngbya majuscula 3L Bacteria UP000003959 495457575, 332353832 EGJ33322.1 WP_008182267.1 455 457 yes 1889578 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 419109, 1238219 Vibrio parahaemolyticus AQ3810, Vibrio parahaemolyticus V-223/04 Bacteria UP000019490 588745397, 582096652 EXF66884.1, EVU11357.1 226 232 no 1889579 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 794903 Opitutaceae bacterium TAV5 Bacteria UP000003813 573472102 AHF89113.1 648 667 yes 1889580 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 398, 698761 Rhizobium tropici, Rhizobium tropici CIAT 899 Bacteria UP000010996 505155613, 440042513 AGB74491.1 WP_015342715.1 fig|698761.4.peg.5326 601 608 yes 1889581 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 283168, 709991 Odoribacter splanchnicus DSM 20712 Bacteria UP000006657 503376297, 324311163 ADY31716.1 WP_013610958.1 fig|709991.3.peg.633 585 585 yes 1889582 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56, 1254432 Sorangium cellulosum, Sorangium cellulosum So0157-2 Bacteria UP000014803 522824370, 521004593 AGP37596.1 WP_020737069.1 462 465 yes 1889583 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 550, 1659708, 1659717, 1400155, 1329852, 1329854 Enterobacter cloacae, Enterobacter sp. GN02358, Enterobacter sp. GN02768, Enterobacter cloacae UCI 50, Enterobacter cloacae UCICRE 3, Enterobacter cloacae UCICRE 9 Bacteria UP000036177, UP000036190, UP000036366, UP000020869, UP000017342, UP000017521 556351283, 838651998, 829401986, 829297668, 578172482, 555078373, 555049097 KLW35889.1, KLQ93394.1, KLP90789.1, EUL32832.1, ESM21613.1, ESL93369.1 WP_023299074.1 626 631 yes 1889584 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 75294, 882086 Saccharomonospora xinjiangensis, Saccharomonospora xinjiangensis XJ-54 Bacteria UP000004691 493281246, 383462772 EID54862.1 WP_006239009.1 546 548 yes 1889585 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59538 Pantholops hodgsonii Mammals 556729356 XP_005960391.1 608 613 yes 1889586 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 102232 Gloeocapsa sp. PCC 73106 Bacteria UP000011180 493575035, 442789341 ELR99003.1 WP_006528189.1 fig|102232.3.peg.1217 453 457 yes 1889587 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 357276, 997876, 997875, 457391 Bacteroides dorei, Bacteroides dorei CL02T12C06, Bacteroides dorei CL02T00C15, Bacteroides sp. 3_1_33FAA Bacteria UP000028592, UP000005974, UP000003300, UP000003976 671717254, 392636315, 392626967, 263235182 AII69526.1, EIY30198.1, EIY21009.1, EEZ20706.1 fig|997875.3.peg.4169, fig|997876.3.peg.3759, fig|457391.3.peg.2437, fig|483217.6.peg.2165 565 565 yes 1889588 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1339265 Pseudomonas aeruginosa, Pseudomonas aeruginosa IGB83 Bacteria UP000065817, UP000024853 685943276, 618774378 KAJ11459.1 WP_031673032.1 627 627 yes 1889589 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1276653 Klebsiella pneumoniae, Klebsiella pneumoniae 700603 Bacteria UP000036212, UP000011985 490312325, 749627584, 471238150 KII55543.1, EMR15654.1 WP_004206747.1 fig|1276653.3.peg.4863 626 631 yes 1889590 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 283686, 1455607 Enterobacter radicincitans, Kosakonia radicincitans UMEnt01/12 Bacteria UP000027068 737925073, 635189410 KDE33276.1 WP_035890313.1 626 631 yes 1889591 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55205, 632518 Caldicellulosiruptor owensensis, Caldicellulosiruptor owensensis OL Bacteria UP000006889 503176599, 311774359 ADQ03846.1 WP_013411260.1 fig|632518.3.peg.266 420 422 yes 1889592 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 1191061 Klebsiella oxytoca, Klebsiella oxytoca E718 Bacteria UP000030350, UP000003127 504650003, 394344053 AFN30174.1 WP_014837105.1 fig|1191061.3.peg.236 626 631 yes 1889593 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 637905 Shewanella violacea DSS12 Bacteria UP000002350 293327611 fig|637905.5.peg.2291 647 662 yes 1889594 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47951 Vibrio cyclitrophicus Bacteria 515139060 WP_016767818.1 640 649 yes 1889595 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1266911 Thioalkalivibrio sp. ALRh Bacteria 518422056 WP_019592263.1 627 629 yes 1889596 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56774, 883109 Eubacterium infirmum, Eubacterium infirmum F0142 Bacteria UP000004504 492846198, 371968244 EHO85706.1 WP_006000152.1 fig|883109.3.peg.823 436 437 yes 1889597 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 591167 Streptomyces flavogriseus ATCC 33331 Bacteria UP000002066 503921186, 320009704 ADW04554.1 WP_014155180.1 fig|591167.6.peg.3205 589 609 yes 1889598 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 130081 Galdieria sulphuraria Plants UP000030680 545710520, 452824042 EME31048.1 XP_005707568.1 556 648 yes 1889599 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 516924999 WP_018168818.1 627 629 yes 1889600 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 502558 Eggerthella sp. YY7918 Bacteria UP000008929 338904308 fig|502558.4.peg.895 461 465 yes 1889601 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46506, 1073351 Bacteroides stercoris, Bacteroides sp. CC31F Bacteria UP000056419, UP000014614 514974455, 514222101 EPH17351.1 WP_016662664.1 fig|1073351.3.peg.3075 562 562 yes 1889602 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 16 518720308 WP_019880884.1 624 626 yes 1889603 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1491, 941968 Clostridium botulinum, Clostridium botulinum H04402 065 Bacteria UP000030128, UP000008979 504334526, 322807229 WP_014521628.1 fig|941968.4.peg.2986 437 437 yes 1889604 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 291644, 997887 Bacteroides salyersiae, Bacteroides salyersiae CL02T12C01 Bacteria UP000005150 494745781, 392666968 EIY60480.1 WP_007481189.1 fig|997887.3.peg.3317 564 564 yes 1889605 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 430914, 1033806 Halorhabdus tiamatea, Halorhabdus tiamatea SARL4B Archaea UP000015381 495799188, 543100739, 528527072 ERJ06474.1 WP_008523767.1 F7PFH8 F7PFH8_9EURY 454 481 yes 1889606 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 831 Butyrivibrio fibrisolvens Bacteria 551011138 WP_022755644.1 436 437 yes 1889607 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 412597 Paracoccus sp. TRP Bacteria 498082329 WP_010396485.1 591 599 yes 1889608 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 579138 Zymomonas mobilis subsp. pomaceae ATCC 29192 Bacteria UP000000491 336294788 AEI37895.1 fig|579138.3.peg.1056 605 607 yes 1889609 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444138, 1116185 Escherichia coli, Escherichia coli 3-073-06_S3_C1, Escherichia coli P0304816.9 Bacteria UP000036210, UP000027682, UP000012309 487359779, 652255321, 477296558 KDZ60557.1, ENF67556.1 WP_001634891.1 fig|1116185.3.peg.4296 626 631 yes 1889610 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 668331, 533247 Raphidiopsis brookii, Raphidiopsis brookii D9 Bacteria UP000052137 496702338, 281197445 EFA72342.1 WP_009343881.1 453 457 yes 1889611 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 190893 Vibrio coralliilyticus Bacteria UP000033403 518107408 WP_019277616.1 640 646 yes 1889612 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1764, 1381559 Mycobacterium avium, Mycobacterium avium subsp. hominissuis 10-5606 Bacteria UP000018551 564971232, 564198434 ETB35230.1 WP_023874736.1 457 458 yes 1889613 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1238231 Vibrio parahaemolyticus 10290 Bacteria UP000015860 532376407 EQL83111.1 132 137 no 1889614 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1238231 Vibrio parahaemolyticus 10290 Bacteria UP000015860 532376408 EQL83112.1 228 228 no 1889615 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3988 Ricinus communis Plants UP000008311 255569269, 223535038 EEF36720.1 XP_002525602.1 543 643 yes 1889616 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28108, 529120 Alteromonas macleodii, Alteromonas macleodii ATCC 27126 Bacteria UP000031168, UP000006102 504760695, 406372414 AFS35669.1 WP_014947797.1 630 636 yes 1889617 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317, 1194418, 1194401, 1194403, 1194402, 1194421, 1194420, 1194408, 1194417, 1194416, 1194409, 1194407, 1189079, 1198673, 1194423, 1194406, 1194415, 1194422, 629266 Pseudomonas syringae, Pseudomonas syringae pv. actinidiae ICMP 9617, Pseudomonas syringae pv. actinidiae ICMP 19094, Pseudomonas syringae pv. actinidiae ICMP 19095, Pseudomonas syringae pv. actinidiae ICMP 18883, Pseudomonas syringae pv. actinidiae ICMP 19099, Pseudomonas syringae pv. actinidiae ICMP 19100, Pseudomonas syringae pv. actinidiae ICMP 19070, Pseudomonas syringae pv. actinidiae ICMP 9855, Pseudomonas syringae pv. actinidiae ICMP 19102, Pseudomonas syringae pv. actinidiae ICMP 19104, Pseudomonas syringae pv. actinidiae ICMP 19068, Pseudomonas syringae pv. actinidiae ICMP 19072, Pseudomonas syringae pv. theae ICMP 3923, Pseudomonas syringae pv. actinidiae ICMP 19071, Pseudomonas syringae pv. actinidiae ICMP 19073, Pseudomonas syringae pv. actinidiae ICMP 19103, Pseudomonas syringae pv. actinidiae ICMP 19098, Pseudomonas syringae pv. actinidiae str. M303091 Bacteria UP000028642, UP000024661, UP000015793, UP000015802, UP000015740, UP000015676, UP000015754, UP000015654, UP000015675, UP000015904, UP000014862, UP000015641, UP000014874, UP000015822, UP000018845, UP000015741, UP000014871, UP000014869, UP000005282 489472026, 627403142, 519279917, 519272064, 519259302, 519249875, 519240654, 519238867, 519228228, 519219975, 519211161, 519200131, 519191037, 519178921, 519170997, 519164027, 519159455, 519158403, 330963737 KCU95491.1, EPN49957.1, EPN44017.1, EPN35733.1, EPN27764.1, EPN19915.1, EPN18398.1, EPN09440.1, EPN02360.1, EPM94955.1, EPM85787.1, EPM78610.1, EPM67901.1, EPM60965.1, EPM54556.1, EPM50336.1, EPM49339.1, EGH63997.1 WP_003377115.1 627 629 yes 1889618 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217696 Acinetobacter sp. NIPH 2036 Bacteria UP000014559 514964943, 514156132 EPG35676.1 WP_016653262.1 fig|1217696.3.peg.3000 626 631 yes 1889619 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666684 Afipia sp. 1NLS2 Bacteria UP000004041 496698764, 298590427 EFI50630.1 WP_009340307.1 632 642 yes 1889620 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 63186 Zobellia galactanivorans Bacteria UP000008898 503760906, 339734415 WP_013994982.1 fig|63186.3.peg.3570 619 619 yes 1889621 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144671 Acinetobacter sp. CIP 53.82 Bacteria UP000018455 491323650, 480151091 ENW88076.1 WP_005181616.1 fig|1144671.3.peg.2532 627 631 yes 1889622 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1118153 Halomonas sp. GFAJ-1 Bacteria UP000004512 496386883, 359298195 EHK62413.1 WP_009095873.1 fig|1118153.6.peg.358 634 638 yes 1889623 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 945692, 644548 Gordonia neofelifaecis, Gordonia sp. AD-6 Bacteria UP000035065 497365177, 326197833 EGD55020.1 WP_009679390.1 553 560 yes 1889624 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 479435 Kribbella flavida DSM 17836 Bacteria UP000007967 283808219 ADB30058.1 fig|479435.4.peg.3361 538 545 yes 1889625 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 257438, 1381097, 1291534 Gluconobacter thailandicus, Gluconobacter thailandicus NBRC 3257, Gluconobacter thailandicus NBRC 3255 Bacteria UP000018209, UP000011890 494493152, 530288459, 453330697 WP_007282621.1 fig|1291534.3.peg.1091 605 631 yes 1889626 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1501391, 1262692 Alistipes sp. 627, Alistipes sp. CAG:157 Bacteria, Environmental samples UP000030889, UP000018346 547375720, 725665077, 524233476 KHE42222.1 WP_022064162.1 572 576 yes 1889627 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 194, 936554 Campylobacter sp. FOBRC14 Bacteria UP000006957 497336239, 401016342 EJP75108.1 WP_009650452.1 fig|360105.6.peg.1421, fig|936554.3.peg.1321 443 444 yes 1889628 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 307124 Meiothermus timidus Bacteria 517278628 WP_018467446.1 433 435 yes 1889629 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 875328 Mycobacterium sp. 506 Bacteria UP000009224 503593261, 333485003 AEF34395.1 WP_013827337.1 fig|875328.3.peg.396 545 547 yes 1889630 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 116 118 no 1889631 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1238193 Vibrio parahaemolyticus, Vibrio parahaemolyticus VP2007-095 Bacteria UP000028114, UP000015803 545080657, 821242945, 726136476, 655634826, 655611855, 655610769, 655607011, 532379124 KKZ05473.1, KHF07631.1, KED34050.1, KED13867.1, KED12874.1, KED09730.1, EQL85814.1 WP_021450630.1 640 646 yes 1889632 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1681, 883062, 1263058 Bifidobacterium bifidum, Bifidobacterium bifidum S17, Bifidobacterium bifidum CAG:234 Bacteria, Environmental samples UP000035497, UP000006869, UP000018218 503128539, 309250962, 524369980 ADO52710.1 WP_013363200.1 fig|883062.5.peg.517 638 918 yes 1889633 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 688 Aliivibrio logei Bacteria 560192586 WP_023604436.1 640 648 yes 1889634 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562020 Neisseria meningitidis N1568 Bacteria UP000003192 325127319 EGC50254.1 fig|562020.3.peg.2626 625 648 yes 1889635 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1716, 1203566, 1203557, 1203562 Corynebacterium sp. KPL1859, Corynebacterium sp. KPL1814, Corynebacterium sp. KPL1855 Bacteria UP000017123, UP000017166, UP000017096 552794205, 550777880, 550764744, 550756739 ERS75922.1, ERS63649.1, ERS55933.1 WP_023026576.1 621 643 yes 1889636 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262872 Dorea sp. CAG:105 Environmental samples UP000017921 546437893, 523990274 WP_021861543.1 435 436 yes 1889637 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 32046, 269084 Synechococcus elongatus, Synechococcus elongatus PCC 6301 Bacteria UP000001175 499561982, 81596642, 56685421 WP_011242765.1 Q5N4X6 THIC_SYNP6 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 932891 fig|269084.3.peg.2138 452 456 yes 1889638 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 293075, 1257025 Leptospira genomosp. 4, Leptospira terpstrae serovar Hualin str. LT 11-33 Bacteria UP000012371 489065340, 476495925 EMY60110.1 WP_002975355.1 500 504 yes 1889639 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1241906 Gordonia sp. NB4-1Y Bacteria UP000011989 464805630 EMP12127.1 fig|1241906.3.peg.2970 98 102 no 1889640 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1495314 Methanoculleus sp. MH98A Archaea 851216599, 635279006 KDE56362.1 WP_048111895.1 A0A063ZIB5 A0A063ZIB5_9EURY 419 424 yes 1889641 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 31234 Caenorhabditis remanei Invertebrates UP000008281 308449277, 308251922 EFO95874.1 XP_003087911.1 326 326 yes 1889642 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 207954 Neptuniibacter caesariensis Bacteria UP000002171 494080972, 89080814 EAR60055.1 WP_007023012.1 628 631 yes 1889643 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 909768, 1343073, 1217689 Acinetobacter baumannii CI78, Acinetobacter sp. ANC 4052 Bacteria UP000018955, UP000013986 507073343, 572042918, 500635624 ETR96422.1, EOQ75034.1 WP_016144117.1 fig|1217689.3.peg.1136 621 625 yes 1889644 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1428, 1195464 Bacillus thuringiensis, Bacillus thuringiensis MC28 Bacteria UP000031834, UP000006284 446737198, 407385382 AFU15883.1 WP_000814454.1 fig|1195464.3.peg.4533 586 586 yes 1889645 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43655, 1117314 Pseudoalteromonas citrea, Pseudoalteromonas citrea NCIMB 1889 Bacteria UP000027154, UP000016487 498051396, 540257227 ERG19382.1 WP_010365552.1 645 650 yes 1889646 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1076588 gamma proteobacterium Hiromi1 Bacteria UP000031631 751601596, 574956890 WP_041069751.1 626 629 yes 1889647 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 837, 1030843 Porphyromonas gingivalis, Porphyromonas gingivalis TDC60 Bacteria UP000028798, UP000009221 503581976, 333804257 WP_013816052.1 fig|1030843.3.peg.1263 587 587 yes 1889648 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1343740 Streptomyces rapamycinicus NRRL 5491 Bacteria UP000030183 521358252 AGP56569.1 588 589 yes 1889649 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384, 754764 Rhizobium leguminosarum, Rhizobium leguminosarum bv. trifolii WSM597 Bacteria UP000005092 489691355, 392849407 EJB01929.1 WP_003595540.1 601 608 yes 1889650 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28131, 246198 Prevotella intermedia, Prevotella intermedia 17 Bacteria UP000067008, UP000010099 504522119, 386375423 AFJ08266.1 WP_014709221.1 fig|246198.10.peg.1071 526 526 yes 1889651 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1563, 768706 Desulfosporosinus orientis, Desulfosporosinus orientis DSM 765 Bacteria UP000006346 503951011, 357213579 AET68197.1 WP_014185005.1 fig|768706.3.peg.2660 420 426 yes 1889652 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1563, 768706 Desulfosporosinus orientis, Desulfosporosinus orientis DSM 765 Bacteria UP000006346 503951010, 357213578 AET68196.1 WP_014185004.1 fig|768706.3.peg.2659 422 432 yes 1889653 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1235794 Enterorhabdus caecimuris B7 Bacteria UP000014204 507792729 EOS50522.1 fig|1235794.3.peg.910 454 456 yes 1889654 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 987057 Burkholderia sp. TJI49 Bacteria UP000003049 325520067 EGC99285.1 642 643 yes 1889655 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28035, 904352, 1409679, 904346 Staphylococcus lugdunensis, Staphylococcus lugdunensis VCU148, Staphylococcus aureus UCIM6116, Staphylococcus epidermidis VCU139 Bacteria UP000057304, UP000026325, UP000022478, UP000003083 488423467, 620701890, 580832092, 374840333 KAK61260.1, EVI53861.1, EHS03832.1 WP_002492852.1 fig|904346.3.peg.1755 578 578 yes 1889656 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1716, 1203564, 1203558, 1203560, 1203563, 1203567 Corynebacterium sp. KPL1857, Corynebacterium sp. KPL1817, Corynebacterium sp. KPL1821, Corynebacterium sp. KPL1856, Corynebacterium sp. KPL1860 Bacteria UP000017098, UP000017176, UP000017152, UP000017094, UP000017122 552775686, 550779181, 550760599, 550754499, 550748867, 550746936 ERS77206.1, ERS59590.1, ERS53788.1, ERS48266.1, ERS46414.1 WP_023021621.1 619 643 yes 1889657 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144338 Pseudomonas sp. GM79 Bacteria UP000007512 495349935, 398233631 EJN19550.1 WP_008074661.1 fig|1144338.3.peg.4786 628 629 yes 1889658 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1583098, 1216362 Fusobacterium hwasookii, Fusobacterium nucleatum ChDC F128 Bacteria UP000004829 492667469, 402257957 EJU08430.1 WP_005916399.1 433 433 yes 1889659 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 222 222 no 1889660 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1311138 Acinetobacter baumannii, Acinetobacter baumannii 42057_6 Bacteria UP000028632, UP000023974 691038105, 610935673 EZI43489.1 WP_031990606.1 621 625 yes 1889661 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 152475, 713585 Thioalkalivibrio thiocyanoxidans, Thioalkalivibrio paradoxus ARh 1 Bacteria UP000005289 493798669, 570728448 AHE99756.1 WP_006746636.1 625 629 yes 1889662 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 871585, 48296, 1310709, 1310685, 1310642, 1310824, 1310720, 1310723, 1310764, 1310791, 1310788, 1310756, 1310711, 1310724, 1310834, 1310670, 1310652, 1310608, 903916, 1147132 Acinetobacter calcoaceticus PHEA-2, Acinetobacter genomosp. 3, Acinetobacter baumannii 1288284, Acinetobacter baumannii 72431, Acinetobacter baumannii 1451147, Acinetobacter baumannii 1264765, Acinetobacter baumannii 478810, Acinetobacter baumannii 1564232, Acinetobacter baumannii 826659, Acinetobacter baumannii 742879, Acinetobacter baumannii 225588, Acinetobacter baumannii 1294243, Acinetobacter baumannii 723929, Acinetobacter baumannii 1245249, Acinetobacter baumannii 263903-2, Acinetobacter baumannii 907131, Acinetobacter baumannii 1475718, Acinetobacter baumannii 1295259, Acinetobacter baumannii WC-136, Acinetobacter pittii 42F Bacteria UP000007477, UP000051522, UP000027130, UP000027022, UP000027043, UP000027251, UP000021488, UP000022865, UP000023199, UP000020888, UP000022254, UP000022715, UP000021979, UP000021821, UP000020028, UP000022283, UP000019943, UP000022741, UP000009876, UP000019188 488049783, 375136780, 820741874, 630565309, 630487091, 630448601, 630395907, 602217446, 602199152, 593651412, 593646492, 593618368, 593556530, 589536496, 589452443, 589185237, 588150251, 587888244, 587806174, 425697157, 325124225, 553273710 KKX42053.1, KCY70558.1, KCX97445.1, KCX63295.1, KCX15318.1, EYT46125.1, EYT28240.1, EXS31346.1, EXS26522.1, EXR99605.1, EXR40103.1, EXI16174.1, EXH34942.1, EXG30351.1, EXE25226.1, EXB76959.1, EXA98300.1, EKU66842.1, ADY83748.1 WP_002121180.1, YP_004997430.1 fig|981332.3.peg.1375, fig|1221304.3.peg.1167, fig|1221302.3.peg.1900, fig|871585.3.peg.3159, fig|1221309.3.peg.2988, fig|575565.3.peg.2180, fig|903916.3.peg.3469, fig|1086014.3.peg.3544, fig|1221289.3.peg.829 621 625 yes 1889663 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 221287 Mastigocladopsis repens Bacteria 515887118 WP_017317701.1 457 459 yes 1889664 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1490, 1233170 Clostridium bifermentans, Clostridium bifermentans ATCC 19299 Bacteria UP000015671 545058158, 531762185 EQK38488.1 WP_021431275.1 437 437 yes 1889665 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570 570 yes 1889666 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 748811, 1223802 sulfur-oxidizing bacterium DSM 22779, Sulfuritalea hydrogenivorans sk43H Bacteria UP000031637 751633140, 572102764 WP_041100944.1 619 619 yes 1889667 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 552810, 552811 Dehalogenimonas lykanthroporepellens, Dehalogenimonas lykanthroporepellens BL-DC-9 Bacteria UP000002349 502983342, 299527706 ADJ26174.1 WP_013218318.1 fig|552811.9.peg.911 431 432 yes 1889668 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106592, 1416753 Ensifer adhaerens, Ensifer adhaerens OV14 Bacteria UP000027454, UP000065540 645057978, 589089342 AHK46097.1 WP_025429258.1 599 607 yes 1889669 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1268622 Acidovorax sp. MR-S7 Bacteria UP000030646 519075020, 524557754 WP_020230895.1 614 618 yes 1889670 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1772, 710686 Mycobacterium smegmatis, Mycobacterium smegmatis JS623 Bacteria UP000029911 505117392, 433295083 AGB20903.1 WP_015304494.1 fig|710686.3.peg.450 511 520 yes 1889671 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 656383 Escherichia coli H120 Bacteria UP000003137 323943589 EGB39698.1 fig|656383.3.peg.4912 578 598 no 1889672 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 552 555 yes 1889673 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33894, 572418 Mycobacterium africanum, Mycobacterium africanum GM041182 Bacteria UP000025286, UP000000298 503754667, 339329848 WP_013988743.1 fig|572418.5.peg.457 544 547 yes 1889674 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217701 Acinetobacter sp. ANC 3880 Bacteria UP000013100 491457051, 480339055 ENX59254.1 WP_005314830.1 fig|1217701.3.peg.2683 626 631 yes 1889675 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43357, 1449976 Kutzneria albida, Kutzneria albida DSM 43870 Bacteria UP000019225 662166653, 578005625 AHH93883.1 WP_030111537.1 551 553 yes 1889676 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144307 Sphingobium sp. AP49 Bacteria UP000006480 494980814, 397724906 EJK85367.1 WP_007706838.1 fig|1144307.3.peg.942 624 631 yes 1889677 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 411464 Desulfovibrio piger ATCC 29098 Bacteria UP000003676 212673238 EEB33721.1 419 431 no 1889678 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487174, 742726 Barnesiella intestinihominis, Barnesiella intestinihominis YIT 11860 Bacteria UP000006044 496137656, 404337411 EJZ63865.1 WP_008862163.1 fig|742726.3.peg.1786 566 566 yes 1889679 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 948, 1392508 Anaplasma phagocytophilum, Anaplasma phagocytophilum str. CRT35 Bacteria UP000033356, UP000053182 763234850, 633297623 KDB57044.1 WP_044104954.1 557 557 yes 1889680 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1390, 1446792, 1150475 Bacillus amyloliquefaciens, Bacillus sp. Pc3, Bacillus amyloliquefaciens subsp. plantarum UCMB5036 Bacteria UP000027101, UP000031124, UP000011722 505229976, 857391673, 743682522, 452079103 KMO07749.1, AJC24654.1 WP_015417078.1 fig|1150475.3.peg.835 590 590 yes 1889681 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1332080, 1114964 Sphingobium baderi, Sphingobium sp. LL03 Bacteria UP000056968, UP000052225 544831625, 530253659 EQA96486.1 WP_021247452.1 612 619 yes 1889682 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1193011 Leptospira fainei serovar Hurstbridge str. BUT 6 Bacteria UP000014540 514179537 EPG73079.1 524 526 yes 1889683 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 171695, 667014 Thermodesulfatator indicus, Thermodesulfatator indicus DSM 15286 Bacteria UP000006793 503672808, 335358457 AEH44138.1 WP_013906884.1 fig|667014.3.peg.260 421 435 no 1889684 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1118157 Stenotrophomonas maltophilia RA8 Bacteria UP000012177 475055624 fig|391008.3.peg.3344, fig|1118157.3.peg.3465 614 646 yes 1889685 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2221, 1090322 Methanolobus tindarius, Methanolobus tindarius DSM 2278 Archaea 564600013, 563512603 ETA67977.1 WP_023845113.1 W9DWA8 W9DWA8_METTI 406 415 no 1889686 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 386429 Pseudoalteromonas sp. BSi20495 Bacteria UP000003050 495411085, 358049105 WP_008135783.1 fig|386429.3.peg.1792 645 650 yes 1889687 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 589 593 yes 1889688 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 222630733 EEE62865.1 175 620 no 1889689 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1476583 Deinococcus phoenicis Bacteria UP000020492 736331036, 597707541 EYB67782.1 WP_034357653.1 603 613 yes 1889690 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 1324967 Campylobacter jejuni, Campylobacter jejuni 255 Bacteria UP000065538, UP000024683 695520252, 631604140 KDA20293.1 WP_032590740.1 430 430 yes 1889691 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 368454, 1230455 Halorubrum arcis, Halorubrum arcis JCM 13916 Archaea 495268207, 445822798 EMA72560.1 WP_007992962.1 M0PUP9 M0PUP9_9EURY 446 478 yes 1889692 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 113287, 887929 Pseudoramibacter alactolyticus, Pseudoramibacter alactolyticus ATCC 23263 Bacteria UP000004754 493647477, 315621299 EFV01269.1 WP_006599072.1 421 437 yes 1889693 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280947 Hyphomonas sp. BH-BN04-4 Bacteria UP000027190 736736332, 630776044 KCZ57591.1 WP_034740254.1 622 631 yes 1889694 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314344 Mariprofundus ferrooxydans Bacteria UP000037016 517106592 WP_018295410.1 621 621 yes 1889695 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 894, 577650 Desulfobulbus propionicus, Desulfobulbus propionicus DSM 2032 Bacteria UP000006365 505938916, 320122531 ADW18077.1 WP_015724617.1 fig|577650.3.peg.2049 429 429 yes 1889696 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1069610 Neisseria meningitidis, Neisseria meningitidis NM255 Bacteria UP000050419, UP000004369 488164064, 402314941 EJU50508.1 WP_002235272.1 fig|1069610.3.peg.2605 625 633 yes 1889697 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 421, 857087 Methylomonas methanica, Methylomonas methanica MC09 Bacteria UP000008888 503585862, 333809041 AEG01711.1 WP_013819938.1 fig|857087.3.peg.3403 621 622 yes 1889698 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262850 Collinsella sp. CAG:166 Environmental samples UP000018358 547476279, 524274197 WP_022094509.1 326 345 no 1889699 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29507, 1049942 Leptospira kirschneri, Leptospira kirschneri serovar Cynopteri str. 3522 CT Bacteria UP000014590 514400637, 514167089 EPG48825.1 WP_016560896.1 440 494 yes 1889700 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46503, 999420 Parabacteroides merdae, Parabacteroides merdae CL03T12C32 Bacteria UP000006271 491869560, 409223272 EKN16209.1 WP_005643401.1 567 568 yes 1889701 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1173028 Oscillatoria sp. PCC 10802 Bacteria 516326911 WP_017717570.1 455 457 yes 1889702 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 553 556 no 1889703 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1125643 Escherichia coli, Escherichia coli P0302293.7 Bacteria UP000036210, UP000012323 486170743, 477114756 END94607.1 WP_001533885.1 fig|1125643.3.peg.4346 626 631 yes 1889704 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2331, 572479 Halanaerobium praevalens, Halanaerobium praevalens DSM 2228 Bacteria UP000006866 504365523, 309388712 ADO76592.1 WP_014552625.1 fig|572479.3.peg.444 428 428 yes 1889705 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 184917, 1206767 Desulfovibrio magneticus, Desulfovibrio magneticus str. Maddingley MBC34 Bacteria UP000006272 493978892, 409981346 EKO37928.1 WP_006921865.1 fig|1206767.3.peg.3319 431 437 yes 1889706 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 1659706, 1659713, 1619244, 1329841 Enterobacter sp. GN02283, Enterobacter sp. GN02548, Enterobacter sp. 35669, Enterobacter sp. BIDMC 29 Bacteria UP000036274, UP000036002, UP000033379, UP000021164 754494695, 829431984, 829344432, 771175786, 578246749 KLR22827.1, KLQ36781.1, KJN28205.1, EUM06847.1 WP_041911590.1 626 631 yes 1889707 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 186802, 665940 Clostridium sp. 7_3_54FAA Bacteria UP000005044 496654851, 354821235 EHF05627.1 WP_009297344.1 fig|665940.3.peg.2770 434 435 yes 1889708 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 640 649 yes 1889709 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265495 Thioalkalivibrio sp. ALE23 Bacteria 517852376 WP_019022584.1 627 629 yes 1889710 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263107 Ruminococcus obeum CAG:39 Environmental samples UP000018059 548167174, 524674953 WP_022389175.1 436 436 yes 1889711 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 876 Desulfovibrio desulfuricans Bacteria 518846189 WP_020002079.1 419 429 no 1889712 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913865 Desulfosporosinus sp. OT Bacteria UP000004928 497304414, 344328002 EGW39406.1 WP_009618631.1 fig|913865.3.peg.2481 418 428 no 1889713 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 913865 Desulfosporosinus sp. OT Bacteria UP000004928 497304412, 344328001 EGW39405.1 WP_009618629.1 fig|913865.3.peg.2480 422 432 yes 1889714 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169319 Citrobacter sp. KTE30 Bacteria UP000014032 507080534, 500555884 EOQ20008.1 WP_016151289.1 fig|1169319.3.peg.4613 626 632 yes 1889715 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1519, 1408889 Clostridium tyrobutyricum, Clostridium tyrobutyricum DIVETGP Bacteria UP000019482 516360811, 587649559 WP_017750844.1 433 433 yes 1889716 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 383631 Methylophilales bacterium HTCC2181 Bacteria UP000054262 495381519, 118440046 EAV46673.1 WP_008106230.1 fig|383631.3.peg.267 624 630 yes 1889717 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1496, 1151259 Clostridium difficile, Clostridium difficile CD22 Bacteria UP000058232, UP000015805 544960847, 531124498 EQE29222.1 WP_021365458.1 433 433 yes 1889718 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1161412 Prevotella sp. ICM33 Bacteria UP000019890 739042618, 573500481 ETT00949.1 WP_036922994.1 525 525 yes 1889719 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913077 Salmonella enterica subsp. enterica serovar Johannesburg str. S5-703 Bacteria UP000003921 353600807 EHC56587.1 fig|913081.3.peg.4828, fig|913071.3.peg.4364, fig|913077.3.peg.4495, fig|913084.3.peg.4511 87 89 no 1889720 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 1263833 Serratia marcescens, Serratia marcescens VGH107 Bacteria UP000055021, UP000011735 491068251, 453066197 EMF07148.1 WP_004929880.1 fig|1263833.3.peg.675 632 647 yes 1889721 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1412588 Salmonella enterica, Salmonella enterica subsp. enterica serovar Enteritidis str. EC20130345 Bacteria UP000054489, UP000023648 740641219, 603350137 AHR38770.1 WP_038426679.1 626 631 yes 1889722 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287232 Mesorhizobium sp. LNHC220B00 Bacteria UP000021223 563577347, 563162454 ESY85905.1 WP_023782503.1 596 611 yes 1889723 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56448, 69929 Xanthomonas arboricola, Xanthomonas arboricola pv. pruni Bacteria UP000050499, UP000050394 759357142, 630371335 KCX00957.1 WP_043087531.1 624 625 yes 1889724 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423 Bacillus subtilis Bacteria UP000030083 518543523 WP_019713730.1 590 590 yes 1889725 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 597 597 yes 1889726 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 1659710, 1643815, 1619246, 550, 1400148, 1400147, 1329827 Enterobacter sp. GN02454, Enterobacter sp. GN02225, Enterobacter sp. 42202, Enterobacter cloacae, Enterobacter cloacae UCI 29, Enterobacter cloacae UCI 24, Enterobacter sp. MGH 23 Bacteria UP000036430, UP000035149, UP000033688, UP000036177, UP000027538, UP000020696, UP000017523 556488855, 829372688, 822865937, 771045098, 723220291, 635786681, 578223686, 555187457 KLQ64550.1, KLG23578.1, KJM29940.1, AIX52943.1, KDF68062.1, EUL83855.1, ESN29990.1 WP_023336586.1 626 631 yes 1889727 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 137716 Ideonella sp. B508-1 Bacteria 551360663 WP_022980010.1 293 296 yes 1889728 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 284 294 no 1889729 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 133448, 500640 Citrobacter youngae, Citrobacter youngae ATCC 29220 Bacteria UP000003880 493739211, 291067282 EFE05391.1 WP_006688370.1 626 632 yes 1889730 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262882 Eubacterium sp. CAG:180 Environmental samples UP000018411 547237459, 524116088 WP_021973634.1 436 436 yes 1889731 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 629268 Pseudomonas syringae pv. aptata str. DSM 50252 Bacteria UP000005484 330983155 EGH81258.1 195 195 no 1889732 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 164451, 572478 Vulcanisaeta distributa, Vulcanisaeta distributa DSM 14429 Archaea UP000006681 503100536, 307594337, 307549538 ADN49603.1 WP_013335328.1, YP_003900654.1 E1QST6 E1QST6_VULDI 413 428 no 1889733 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454753 Candidatus Caldatribacterium saccharofermentans Bacteria 516485701 WP_017874145.1 430 431 yes 1889734 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 1365654 Campylobacter jejuni, Campylobacter jejuni 20176 Bacteria UP000065538, UP000024950 763401456, 631618846 KDA34684.1 WP_044258326.1 430 430 yes 1889735 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3702 Arabidopsis thaliana Plants UP000006548 UP000006548 557805280 O82392 THIC_ARATH Phosphomethylpyrimidine synthase, chloroplastic 556 582 4N7Q, 4S29, 4S28, 4S27, 4S26, 4S25 4.1.99.17 yes 1889736 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1736, 903814 Eubacterium limosum, Eubacterium limosum KIST612 Bacteria UP000061973, UP000006873 503146965, 308740656 ADO38316.1 WP_013381626.1 fig|903814.3.peg.3100 443 444 yes 1889737 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 502821 Halomonas sp. S18214 Bacteria 515481387 WP_016914655.1 635 638 yes 1889738 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 196164 Corynebacterium efficiens YS-314 Bacteria UP000002618 23493246 Q8FPT3 THIC_COREF Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 300296 fig|196164.1.peg.1407 592 650 yes 1889739 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47490, 1421016, 1094508 Thermoanaerobacterium aotearoense, Thermoanaerobacterium aotearoense SCUT27, Thermoanaerobacterium saccharolyticum JW/SL-YS485 Bacteria UP000019481, UP000006178 504571216, 569526434, 389570042 ETO38184.1, AFK86447.1 WP_014758318.1 fig|1094508.3.peg.1461 434 434 yes 1889740 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 279369 Sphingopyxis baekryungensis Bacteria 550924559 WP_022673029.1 625 635 yes 1889741 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 382, 1107881 Sinorhizobium meliloti, Sinorhizobium meliloti CCNWSX0020 Bacteria UP000028953, UP000004038 489624976, 359504700 EHK77232.1 WP_003529416.1 fig|1107881.3.peg.2941 600 611 yes 1889742 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1493, 573061 Clostridium cellulovorans, Clostridium cellulovorans 743B Bacteria UP000002730 497760423, 302578497 ADL52509.1 WP_010074607.1 fig|573061.3.peg.4328 435 435 yes 1889743 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2315, 937775 Methanoplanus limicola, Methanoplanus limicola DSM 2279 Archaea UP000005741 490178215, 373907004 EHQ35108.1 WP_004076839.1 H1YZ84 H1YZ84_9EURY 414 422 no 1889744 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1164990 Richelia intracellularis Bacteria UP000019767 739360747, 605042039 WP_037222091.1 457 459 yes 1889745 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630, 1262466 Yersinia enterocolitica, Yersinia enterocolitica (type O:3) str. YE12/03 Bacteria UP000029427, UP000018145 554499211, 510590703 WP_023160956.1 617 628 yes 1889746 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 49338, 138119 Desulfitobacterium hafniense, Desulfitobacterium hafniense Y51 Bacteria UP000054623, UP000001946 698316732, 89333595 fig|138119.3.peg.1673 431 435 yes 1889747 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83986, 1201294, 86622 Methanoculleus bourgensis, Methanoculleus bourgensis MS2, Methanoculleus sp. MAB1 Archaea UP000009007, UP000069850 504680091, 396938962 WP_014867193.1 A0A167STY3, A0A0X3BLN9, I7LJP8 A0A167STY3_9EURY, A0A0X3BLN9_9EURY, I7LJP8_METBM 419 424 yes 1889748 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43080 Sulfolobus islandicus Archaea 515103015 WP_016732185.1 433 433 yes 1889749 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83816, 634498 Methanobrevibacter ruminantium, Methanobrevibacter ruminantium M1 Archaea UP000008680 502720262, 288559701, 288542411 ADC46295.1 WP_012955246.1, YP_003423187.1 D3E0P9 D3E0P9_METRM 10381443 423 424 yes 1889750 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 1460691 Pseudomonas sp. P482 Bacteria UP000027121 497907409, 641462993 KDN99534.1 WP_010221565.1 fig|314608.4.peg.1075 627 628 yes 1889751 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 516867878 WP_018138208.1 627 629 yes 1889752 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 853, 411483 Faecalibacterium prausnitzii, Faecalibacterium prausnitzii A2-165 Bacteria UP000004619 492708545, 257199449 EEU97733.1 WP_005930119.1 fig|411483.3.peg.521 435 436 yes 1889753 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317, 1357279 Pseudomonas syringae, Pseudomonas syringae CC1557 Bacteria UP000028642, UP000019089 644970075, 574599422 AHG43006.1 WP_025390829.1 627 629 yes 1889754 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 443143 Geobacter sp. M18 Bacteria UP000001442 505933791, 320128093 ADW15653.1 WP_015722472.1 fig|443143.3.peg.898 433 435 yes 1889755 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66865, 1283301 Streptomyces afghaniensis, Streptomyces afghaniensis 772 Bacteria UP000015001 519330937, 514942216 EPJ40740.1 WP_020271169.1 592 594 yes 1889756 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 409998, 1193069 Leptospira wolffii, Leptospira wolffii str. Khorat-H2 Bacteria UP000014564 514353557, 514176578 EPG66286.1 WP_016545285.1 530 531 yes 1889757 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1202716, 858455 Rhodomicrobium sp. JA755, Rhodomicrobium sp. JA643 Bacteria UP000026572 739381602, 617472840 KAI93245.1 WP_037242283.1 348 351 no 1889758 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 441501 Corynebacterium massiliense Bacteria 551241879 WP_022862240.1 607 609 yes 1889759 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116131 Escherichia coli, Escherichia coli P02997067.6 Bacteria UP000036210, UP000012363 485876411, 476939003 ENC28285.1 WP_001472684.1 fig|1116131.3.peg.5040 626 631 yes 1889760 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262848 Clostridium sp. CAG:964 Environmental samples UP000018136 547894323, 524550826 WP_022299066.1 437 437 yes 1889761 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 426114 Thiomonas sp. 3As Bacteria UP000002372 294339898 624 672 yes 1889762 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36808 Corynebacterium bovis Bacteria 497952044 WP_010266200.1 568 574 yes 1889763 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1385935 Leptolyngbya sp. Heron Island J Bacteria UP000017515 553083054 ESA34825.1 439 440 yes 1889764 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1137848 Clostridium arbusti Bacteria 497925243 WP_010239399.1 433 433 yes 1889765 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29449, 993047 Rhizobium etli, Rhizobium etli CNPAF512 Bacteria UP000003712 490815170, 327189856 EGE56991.1 WP_004677276.1 fig|993047.3.peg.4701 600 610 yes 1889766 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 177439 Desulfotalea psychrophila LSv54 Bacteria UP000000602 81641443, 50877387 Q6AK99 THIC_DESPS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 424972 fig|177439.1.peg.2498 433 434 yes 1889767 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 32008, 640512 Burkholderia sp. CCGE1003 Bacteria UP000001550 503103920, 307583672 ADN57070.1 WP_013338692.1 fig|640512.3.peg.3701 642 643 yes 1889768 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28175, 675816 Vibrio orientalis, Vibrio orientalis CIP 102891 Bacteria UP000003515 490552507, 342814104 EGU49056.1 WP_004417616.1 fig|675816.3.peg.142 640 646 yes 1889769 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1069622 Neisseria meningitidis, Neisseria meningitidis NM3001 Bacteria UP000050419, UP000005054 488172455, 402342823 EJU77979.1 WP_002243663.1 fig|1069622.3.peg.1871 625 633 yes 1889770 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 837, 1195243 Porphyromonas gingivalis, Porphyromonas gingivalis JCVI SC001 Bacteria UP000028798, UP000016542 490722107, 482527495 EOA10330.1 WP_004584667.1 587 587 yes 1889771 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 742814 Fusobacterium necrophorum subsp. funduliforme 1_1_36S Bacteria UP000003092 371655726 EHO21064.1 fig|742814.3.peg.610 393 395 yes 1889772 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 948, 1392507 Anaplasma phagocytophilum, Anaplasma phagocytophilum str. Norway variant2 Bacteria UP000033356, UP000053801 763281397, 633295289 KDB54793.1 WP_044142798.1 557 557 yes 1889773 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173468 Salmonella enterica, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000200 Bacteria UP000054489, UP000017602 555257095, 554323339 ESH59870.1 WP_023239852.1 626 631 yes 1889774 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111504, 1094552 Bartonella birtlesii, Bartonella birtlesii LL-WM9 Bacteria UP000008748 493637469, 395411802 EJF78323.1 WP_006589246.1 fig|1094552.3.peg.323 601 610 yes 1889775 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 505 515 yes 1889776 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35619, 467200 Streptomyces griseoflavus, Streptomyces griseoflavus Tu4000 Bacteria UP000037504, UP000002968 491067664, 302477332 EFL40425.1 WP_004929295.1 594 598 yes 1889777 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 379896 Paenibacillus fonticola Bacteria 518468309 WP_019638516.1 593 593 yes 1889778 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116070 Escherichia coli, Escherichia coli P0301867.7 Bacteria UP000036210, UP000012292 485911435, 477441899 ENH05860.1 WP_001490383.1 fig|1116070.3.peg.4465 626 631 yes 1889779 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1034, 883079 Afipia clevelandensis, Afipia clevelandensis ATCC 49720 Bacteria UP000001095 488800532, 410888056 EKS35860.1 WP_002712938.1 fig|883079.3.peg.2103 634 643 yes 1889780 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 147266, 1156935 Agrobacterium albertimagni, Agrobacterium albertimagni AOL15 Bacteria UP000007123 493775800, 407749671 EKF61182.1 WP_006724270.1 fig|1156935.5.peg.282 603 612 yes 1889781 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29448 Bradyrhizobium elkanii Bacteria UP000032215 515290801 WP_016840910.1 622 632 yes 1889782 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537210 Mycobacterium tuberculosis T17 Bacteria UP000026440 289542092 EFD45741.1 529 546 yes 1889783 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 479433 Catenulispora acidiphila DSM 44928 Bacteria UP000000851 256364129 ACU77626.1 fig|479433.5.peg.8938 595 601 yes 1889784 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 364410, 1052004 Granulibacter bethesdensis, Granulibacter bethesdensis CGDNIH3 Bacteria UP000019438 644184019, 586600091 AHJ61852.1 WP_025285691.1 603 610 yes 1889785 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262975 Sutterella sp. CAG:351 Environmental samples UP000018107 548225413, 524746506 WP_022444353.1 513 514 yes 1889786 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1299333 Mycobacterium xenopi 3993 Bacteria UP000023198 576429109 EUA22818.1 96 141 no 1889787 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 290512 Prosthecochloris aestuarii DSM 271 Bacteria UP000002725 290457625 B4S9A9 THIC_PROA2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6848918 561 562 yes 1889788 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169161 Streptomyces sp. CNY243 Bacteria 517681666 WP_018851874.1 597 602 yes 1889789 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81462, 525903 Thermanaerovibrio acidaminovorans, Thermanaerovibrio acidaminovorans DSM 6589 Bacteria UP000002030 502633533, 269792968, 269100603 ACZ19590.1 WP_012870101.1, YP_003317872.1 10290843 fig|525903.4.peg.275 418 428 yes 1889790 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314722, 743721 Pseudoxanthomonas suwonensis, Pseudoxanthomonas suwonensis 11-1 Bacteria UP000033067, UP000008632 503299479, 317464578 ADV26310.1 WP_013534140.1 fig|743721.3.peg.469 622 625 yes 1889791 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2293, 879212 Desulfobacter postgatei, Desulfobacter postgatei 2ac9 Bacteria UP000005778 490173402, 389400881 EIM63103.1 WP_004072039.1 429 429 yes 1889792 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 691, 1219067 Vibrio natriegens, Vibrio natriegens NBRC 15636 Bacteria UP000014847 520913971, 519121591 EPM42107.1 WP_020333407.1 640 646 yes 1889793 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4155 Mimulus guttatus Plants UP000030748 848863444, 604342519, 604342518 EYU41549.1, EYU41548.1 XP_012832487.1 552 647 yes 1889794 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36745, 931276 Clostridium saccharoperbutylacetonicum, Clostridium saccharoperbutylacetonicum ATCC 27021 Bacteria UP000011728 505203842, 451783650 AGF54618.1 WP_015390944.1 fig|931276.4.peg.4819 435 436 yes 1889795 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1450694 Bacillus sp. TS-2 Bacteria UP000019504 591277505 588 588 yes 1889796 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144308 Brevibacillus sp. BC25 Bacteria UP000007278 495002196, 398028010 EJL21534.1 WP_007728210.1 fig|1144308.3.peg.5225 584 584 yes 1889797 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 191026, 1121451 Desulfovibrio hydrothermalis, Desulfovibrio hydrothermalis AM13 = DSM 14728 Bacteria UP000010808 505150605, 436842830, 432171736 WP_015337707.1, YP_007327208.1 419 421 no 1889798 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1125634 Escherichia coli, Escherichia coli 174750 Bacteria UP000036210, UP000012316 490119011, 476272968 EMW91228.1 WP_004019540.1 fig|1125634.3.peg.4779 626 631 yes 1889799 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 419186, 1230459 Natrinema gari, Natrinema gari JCM 14663 Archaea 495733039, 445624233 ELY77622.1 WP_008457618.1 L9YVX0 L9YVX0_9EURY 456 481 yes 1889800 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1244869 Magnetospirillum sp. SO-1 Bacteria UP000011744 495889166, 452966663 EME71672.1 WP_008613745.1 fig|1244869.3.peg.401 602 618 yes 1889801 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354356, 700598 Niastella koreensis, Niastella koreensis GR20-10 Bacteria UP000005438 503985797, 361060886 AEV99877.1 WP_014219791.1 fig|700598.3.peg.3664 628 628 yes 1889802 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 378211 Methyloversatilis universalis Bacteria 517038847 WP_018227665.1 642 642 yes 1889803 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 859350 marine archaeal group 1 strain BD31 Archaea 386805735 EIJ65242.1 I3D0J9 I3D0J9_9ARCH 451 453 yes 1889804 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1495314 Methanoculleus sp. MH98A Archaea 635277753 KDE55231.1 A0A063ZEB7 A0A063ZEB7_9EURY 413 429 no 1889805 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 548, 1028307 Enterobacter aerogenes, Enterobacter aerogenes KCTC 2190 Bacteria UP000056714, UP000008881 505806251, 336248129, 822780451, 334734185 KLF39305.1, AEG96560.1 WP_015704012.1, YP_004591839.1 fig|1028307.3.peg.1627 626 631 yes 1889806 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 69218, 500639 Enterobacter cancerogenus, Enterobacter cancerogenus ATCC 35316 Bacteria UP000030397, UP000003468 493176210, 288316961 EFC55899.1 WP_006176760.1 626 631 yes 1889807 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 587753, 1415170 Pseudomonas chlororaphis, Pseudomonas chlororaphis subsp. aurantiaca PB-St2 Bacteria UP000027603, UP000018756 565889032, 564818908 ETD35412.1 WP_023970195.1 628 629 yes 1889808 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 254759 Bacillus fordii Bacteria 517535363 WP_018705571.1 594 594 yes 1889809 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 376805, 667015 Bacteroides salanitronis, Bacteroides salanitronis DSM 18170 Bacteria UP000007486 503384825, 324320240 ADY38131.1 WP_013619486.1 fig|667015.3.peg.3778 563 563 yes 1889810 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 1659712, 1104326 Enterobacter sp. GN02534, Enterobacter cloacae subsp. dissolvens SDM Bacteria UP000036266, UP000002891 504643145, 829353035, 392323056 KLQ45320.1, AFM58009.1 WP_014830247.1 626 631 yes 1889811 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1417296 Defluviimonas sp. 20V17 Bacteria UP000026305 737872649, 632829878 KDB04802.1 WP_035839464.1 590 598 yes 1889812 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169154 Streptomyces sp. CNT372 Bacteria 517675933 WP_018846141.1 589 591 yes 1889813 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1122247 Mycobacterium hassiacum DSM 44199 Bacteria UP000006265 407376433 EKF25362.1 fig|1122247.3.peg.575 497 497 yes 1889814 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 494419 Arthrobacter sp. TB 23 Bacteria 518314057 WP_019484264.1 568 573 yes 1889815 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158154 Thioalkalivibrio sp. AKL6 Bacteria 516880876 WP_018144983.1 627 629 yes 1889816 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 243231, 35554, 663917 Geobacter sulfurreducens PCA, Geobacter sulfurreducens, Geobacter sulfurreducens KN400 Bacteria UP000000577 UP000000577, UP000032622, UP000000389 39995711, 499243726, 779733956, 298504722, 39982475 AJY70358.1, ADI83445.1, AAR33935.1 NP_951662.1, WP_010941266.1 380895 fig|243231.1.peg.600, fig|663917.3.peg.588 436 436 yes 1889817 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 868131 Methanobacterium sp. SWAN-1 Archaea UP000009231 503590579, 333824491 AEG17153.1 WP_013824655.1 F6D7S4 F6D7S4_METPW 432 432 yes 1889818 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1286, 1405498 Staphylococcus simulans, Staphylococcus simulans UMC-CNS-990 Bacteria UP000058481, UP000017131 552759906, 550797793 ERS93030.1 WP_023015807.1 581 581 yes 1889819 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 935593 Neisseria meningitidis, Neisseria meningitidis M04-240196 Bacteria UP000050419, UP000007481 504394487, 325206945 ADZ02398.1 WP_014581589.1 fig|935593.3.peg.2649 625 633 yes 1889820 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 550672 Escherichia coli B088 Bacteria UP000002798 291321331 EFE60772.1 233 236 no 1889821 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550672 Escherichia coli B088 Bacteria UP000002798 291321330 EFE60771.1 377 379 yes 1889822 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 864702 Oscillatoriales cyanobacterium JSC-12 Bacteria UP000001332 497242634, 410710584 EKQ68091.1 WP_009556856.1 454 457 yes 1889823 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40215, 1217665 Acinetobacter junii, Acinetobacter junii NIPH 182 Bacteria UP000018463 491095767, 480021260 ENV62169.1 WP_004957371.1 fig|1217665.3.peg.2860 626 631 yes 1889824 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47951 Vibrio cyclitrophicus Bacteria 498126490 WP_010440646.1 640 649 yes 1889825 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 497954666 WP_010268822.1 598 600 yes 1889826 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1390 Bacillus amyloliquefaciens Bacteria UP000027101 515986725 WP_017417308.1 590 590 yes 1889827 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 477976, 768670 Calditerrivibrio nitroreducens, Calditerrivibrio nitroreducens DSM 19672 Bacteria UP000007039 503216220, 312939476 ADR18668.1 WP_013450881.1 fig|768670.3.peg.831 425 425 yes 1889828 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 273526 Serratia marcescens, Serratia marcescens subsp. marcescens Db11 Bacteria UP000055021, UP000018979 644369012, 560176211 WP_025304947.1 632 647 yes 1889829 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 624 636 yes 1889830 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262958 Ruminococcus sp. CAG:403 Environmental samples UP000017925 548209425, 524729555 WP_022429158.1 439 439 yes 1889831 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 889487 Streptomyces sp. S4 Bacteria 498330176 WP_010644332.1 595 597 yes 1889832 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1238219 Vibrio parahaemolyticus V-223/04 Bacteria 582096643 EVU11350.1 361 361 no 1889833 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1335422, 1138871, 1232724, 1138383, 1138382, 487521 Mycobacterium intracellulare MIN_061107_1834, Mycobacterium yongonense 05-1390, Mycobacterium indicus pranii MTCC 9506, Mycobacterium intracellulare MOTT-64, Mycobacterium intracellulare MOTT-02, Mycobacterium intracellulare ATCC 13950 Bacteria UP000022954, UP000014801, UP000007329, UP000008003, UP000008002, UP000008004 576337635, 521368349, 405131466, 378812118, 378806863, 378801690 ETZ32233.1, AGP66184.1, AFS16721.1, AFC56252.1, AFC50998.1, AFC45826.1 fig|487521.5.peg.683, fig|1168288.3.peg.3905, fig|1232724.3.peg.4766, fig|1138382.3.peg.4603, fig|1168287.3.peg.4735, fig|1214063.3.peg.954 532 534 yes 1889834 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1022, 395493 Beggiatoa alba, Beggiatoa alba B18LD Bacteria UP000005744 488760822, 386427950 EIJ41778.1 WP_002684033.1 623 628 yes 1889835 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1454753 Candidatus Caldatribacterium saccharofermentans Bacteria 516485060 WP_017873504.1 153 154 no 1889836 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263028, 813 Firmicutes bacterium CAG:536, Chlamydia trachomatis Environmental samples, Bacteria UP000018332, UP000037498 547475000, 815051263, 524271291 WP_022093368.1 443 443 yes 1889837 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262974 Succinatimonas sp. CAG:777 Environmental samples UP000018241 546740743, 524009973 WP_021889403.1 485 518 yes 1889838 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 72000 Kocuria rhizophila Bacteria UP000036229 518139343 WP_019309551.1 591 617 yes 1889839 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81972 Arabidopsis lyrata subsp. lyrata Plants UP000008694 297822681, 297325062 EFH55482.1 XP_002879223.1 556 645 4N7Q, 4S29, 4S28, 4S27, 4S26, 4S25 yes 1889840 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 471 Acinetobacter calcoaceticus Bacteria UP000032475 515957169 WP_017387752.1 621 625 yes 1889841 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1192124 Burkholderia sp. lig30 Bacteria UP000027020 740930976, 632868190 KDB05986.1 WP_038716007.1 642 643 yes 1889842 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 909768, 1310689, 1217672 Acinetobacter baumannii 1578804, Acinetobacter pittii CIP 70.29 Bacteria UP000022740 491221124, 588218371, 480075968 EXE90997.1, ENW14654.1 WP_005079439.1 fig|1217672.3.peg.1652 621 625 yes 1889843 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 411486 Clostridium sp. M62/1 Bacteria UP000004936 291073660 EFE11024.1 428 429 yes 1889844 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 277, 504728 Meiothermus ruber, Meiothermus ruber DSM 1279 Bacteria UP000032107, UP000006655 502779322, 481062588, 290471381 AGK05751.1, ADD28800.1 WP_013014298.1 fig|504728.4.peg.2017 434 436 yes 1889845 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316, 96563, 996285 Pseudomonas stutzeri, Pseudomonas stutzeri LMG 11199T, Pseudomonas stutzeri DSM 4166 Bacteria UP000037382, UP000008932, UP000000481 503750125, 338803221, 327482470 AEJ07053.1, AEA85780.1 WP_013984201.1 fig|96563.4.peg.3769, fig|996285.3.peg.3932 627 627 yes 1889846 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1226755 Paenibacillus sp. FSL R7-269 Bacteria UP000019056 738798939, 573558053 ETT56768.1 WP_036690061.1 562 564 yes 1889847 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1379159 Dyella jiangningensis Bacteria UP000024387 740837947, 612505857 AHX15695.1 WP_038623230.1 622 625 yes 1889848 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1224164 Corynebacterium vitaeruminis DSM 20294 Bacteria UP000019222 582019736 AHI23079.1 603 606 yes 1889849 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262928 Prevotella sp. CAG:487 Environmental samples UP000018275 547259177, 524139753 WP_021994242.1 566 567 yes 1889850 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 848, 936562, 1316588, 1196653 Fusobacterium sp. CM21, Fusobacterium nucleatum CTI-7, Fusobacterium nucleatum subsp. fusiforme ATCC 51190 Bacteria UP000019058, UP000017138, UP000007653 492657537, 573491434, 551185060, 395488030 ETS92246.1, ERT48894.1, EJG08924.1 WP_005913510.1 fig|1196653.3.peg.1289 433 433 yes 1889851 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 361055 Rubritalea marina Bacteria 517799750 WP_018969958.1 682 702 yes 1889852 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28068, 983917 Rubrivivax gelatinosus, Rubrivivax gelatinosus IL144 Bacteria UP000007883 504242652, 381380079 WP_014429754.1 fig|983917.3.peg.3480 622 636 yes 1889853 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40215, 575587 Acinetobacter junii, Acinetobacter junii SH205 Bacteria UP000018442 491545923, 262310968 EEY92055.1 WP_005403539.1 626 631 yes 1889854 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1763, 1299331, 1324269, 1299329, 1168288, 1168287 Mycobacterium intracellulare 1956, Mycobacterium sp. TKK-01-0059, Mycobacterium avium 2285 (S), Mycobacterium sp. H4Y, Mycobacterium sp. MOTT36Y Bacteria UP000029901, UP000028319, UP000031751, UP000012622, UP000002868 495536802, 698187618, 657001881, 576459844, 576435141, 442765181, 386791488 AIT87494.1, KEF98264.1, EUA53451.1, EUA28826.1, ELR83179.1, AFJ37607.1 WP_008261381.1 fig|1168288.3.peg.3905, fig|1232724.3.peg.4766, fig|487521.5.peg.683, fig|1168287.3.peg.4735, fig|1214063.3.peg.954 543 546 yes 1889855 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397528 Halomonas sp. PBN3 Bacteria UP000017115 552548379, 550790021 ERS87799.1 WP_023006365.1 629 629 yes 1889856 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1744, 754252 Propionibacterium freudenreichii, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1 Bacteria UP000049199, UP000000936 502926950, 296923000 WP_013161926.1 fig|754252.3.peg.2007 625 634 yes 1889857 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1218169 Pseudomonas putida S11 Bacteria UP000010133 402213416 EJT84765.1 fig|1218169.3.peg.3406 606 606 yes 1889858 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 189518, 173, 996803, 1218578, 1049930, 1001588, 996802, 573825 Leptospira interrogans serovar Lai str. 56601, Leptospira interrogans, Leptospira interrogans str. 2002000626, Leptospira interrogans str. 2002000632, Leptospira interrogans str. 2002000623, Leptospira interrogans str. 2002000621, Leptospira interrogans str. 2002000624, Leptospira interrogans serovar Lai str. IPAV Bacteria UP000001408 UP000001408, UP000037872, UP000012329, UP000011887, UP000001333, UP000001084, UP000006264, UP000005628 24213680, 487898812, 476382335, 463304001, 410581028, 410573816, 409942691, 353457056, 24194490, 29337055 EMY02105.1, EMJ71806.1, EKQ48843.1, EKQ36860.1, EKN88299.1, AER01601.1, AAN48179.1 NP_711161.1, WP_001972278.1 Q8F7G5 THIC_LEPIN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 290434 fig|189518.1.peg.980, fig|1218579.3.peg.5510, fig|996803.3.peg.1295, fig|1049912.3.peg.620, fig|1218578.3.peg.3147, fig|1049911.3.peg.1922 441 495 yes 1889859 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 86661, 1053243, 1053244, 714359 Bacillus cereus VD196, Bacillus cereus VD200, Bacillus thuringiensis BMB171 Bacteria UP000014023, UP000006513, UP000001658 446737228, 500346401, 401288390, 296326702 EOO64724.1, EJR94143.1, ADH09630.1 WP_000814484.1 fig|714359.3.peg.5153, fig|1053244.3.peg.5216, fig|1209364.3.peg.5519, fig|1053243.3.peg.4288 586 586 yes 1889860 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 1339336 Bacteroides fragilis, Bacteroides fragilis str. 34-F-2 #13 Bacteria UP000036847, UP000020197 695526826, 595926841 EXY35515.1 WP_032593164.1 564 564 yes 1889861 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169155 Streptomyces sp. CNT302 Bacteria 517720439 WP_018890647.1 591 595 yes 1889862 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 121872, 1227489 Haloterrigena thermotolerans, Haloterrigena thermotolerans DSM 11522 Archaea 493700476, 445657736 ELZ10560.1 WP_006650258.1 M0BI85 M0BI85_9EURY 448 476 yes 1889863 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 546271 Selenomonas sputigena ATCC 35185 Bacteria UP000011124 260862225 EEX76725.1 440 443 yes 1889864 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 876270 Beijerinckiaceae bacterium SOP9 Bacteria 519018240 WP_020174115.1 610 612 yes 1889865 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1182682 Escherichia coli, Escherichia coli KTE75 Bacteria UP000036210, UP000010714 486244877, 431150238 ELE51295.1 WP_001562420.1 fig|1182682.3.peg.4947 626 631 yes 1889866 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47678, 997873 Bacteroides caccae, Bacteroides caccae CL03T12C61 Bacteria UP000002965 491935966, 392627849 EIY21884.1 WP_005680886.1 fig|997873.3.peg.1700 562 562 yes 1889867 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 515256 Bartonella sp. 1-1C Bacteria 319406916 600 608 yes 1889868 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 291176, 1094557 Bartonella melophagi, Bartonella melophagi K-2C Bacteria UP000009017 494742014, 395423587 EJF89781.1 WP_007477422.1 fig|1094557.3.peg.873 602 611 yes 1889869 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 936381 Selenomonas sp. CM52 Bacteria UP000003116 497332205, 402277993 EJU27059.1 WP_009646418.1 fig|936381.3.peg.1621 433 435 yes 1889870 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262741 Bacteroides sp. CAG:530 Environmental samples UP000018392 547712812, 524317376 WP_022129476.1 568 568 yes 1889871 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 469603 Fusobacterium nucleatum, Fusobacterium sp. 3_1_33 Bacteria UP000005768 496074342, 260196854 EEW94376.1 WP_008798849.1 433 433 yes 1889872 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1240557 Thioalkalivibrio sp. ALJ3 Bacteria 517690721 WP_018860929.1 627 629 yes 1889873 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1177931 Thiovulum sp. ES Bacteria UP000005330 495628000, 394445339 EJF06269.1 WP_008352579.1 fig|1177931.3.peg.1636 342 344 yes 1889874 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56688, 1227468, 1227467, 1227486 Halorubrum distributum JCM 10118, Halorubrum distributum JCM 9100, Halorubrum terrestre JCM 10247 Archaea UP000011614 490736237, 445702982, 445694543, 445682743 ELZ54921.1, ELZ46668.1, ELZ35156.1 WP_004598565.1 M0DI31, M0EHX3, M0F4G3 M0DI31_9EURY, M0EHX3_9EURY, M0F4G3_9EURY 446 478 yes 1889875 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 220697, 1123366 Thalassospira xiamenensis, Thalassospira xiamenensis M-5 = DSM 17429 Bacteria UP000007127 494149427, 745807722 AJD50418.1 WP_007089172.1 fig|1123366.3.peg.988 603 607 yes 1889876 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 243231, 35554, 663917 Geobacter sulfurreducens PCA, Geobacter sulfurreducens, Geobacter sulfurreducens KN400 Bacteria UP000000577 UP000000577, UP000032622, UP000000389 39998096, 499246095, 779732854, 298507037, 39985041, 47606073 AJY69256.1, ADI85760.1, AAR36397.1 NP_954047.1, WP_010943635.1 P61425 THIC_GEOSL Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 383321 fig|663917.3.peg.2955, fig|243231.1.peg.2985 430 435 yes 1889877 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262739 Bacteroides sp. CAG:443 Environmental samples UP000018098 547824981, 524457449 WP_022233299.1 564 564 yes 1889878 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 516393808 WP_017783207.1 662 680 yes 1889879 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 346377 Echinicola pacifica Bacteria 517285185 WP_018474003.1 623 623 yes 1889880 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 190898, 1286635 Desulfotignum phosphitoxidans, Desulfotignum phosphitoxidans DSM 13687 Bacteria UP000014216 494021969, 474490580 EMS81499.1 WP_006964241.1 fig|1286635.3.peg.665 427 427 yes 1889881 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287334 Mesorhizobium sp. LSJC277A00 Bacteria UP000021660 563460503, 562942627 ESW63430.1 WP_023685604.1 596 611 yes 1889882 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1079478 Salmonella enterica, Salmonella enterica subsp. enterica serovar Muenchen str. baa1674 Bacteria UP000054489, UP000017420 555234484, 554209463 ESG47613.1 WP_023221194.1 626 631 yes 1889883 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116050, 1116048 Escherichia coli, Escherichia coli P0299917.4, Escherichia coli P0299917.2 Bacteria UP000036210, UP000012306, UP000012190 485880465, 476964447, 476955338 ENC52239.1, ENC43806.1 WP_001476037.1 fig|1116050.3.peg.4511, fig|1116048.3.peg.4479 626 631 yes 1889884 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262756 Blautia sp. CAG:257 Environmental samples UP000018056 547447100, 524240388 WP_022066969.1 433 434 yes 1889885 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1346290 Methyloversatilis sp. 3t Bacteria 517223529 WP_018412347.1 637 641 yes 1889886 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37329, 247156 Nocardia farcinica, Nocardia farcinica IFM 10152 Bacteria UP000057820, UP000006820 499525210, 81602361, 54018798 WP_011211850.1 Q5YNS3 THIC_NOCFA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 771051 fig|247156.1.peg.5110 545 547 yes 1889887 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 529 547 yes 1889888 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 454155, 762982 Paraprevotella xylaniphila, Paraprevotella xylaniphila YIT 11841 Bacteria UP000005546 495899325, 329576608 EGG58111.1 WP_008623904.1 574 575 yes 1889889 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 171164, 797114 Halosimplex carlsbadense, Halosimplex carlsbadense 2-9-1 Archaea 493938642, 445674922 ELZ27457.1 WP_006882881.1 M0CYF4 M0CYF4_9EURY 437 467 yes 1889890 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324, 1429851 Stenotrophomonas maltophilia, Stenotrophomonas maltophilia 5BA-I-2 Bacteria UP000034806, UP000019252 727708496, 581973756 EVT73736.1 WP_033831956.1 613 614 yes 1889891 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 488939, 555779 Desulfonatronospira thiodismutans, Desulfonatronospira thiodismutans ASO3-1 Bacteria UP000005496 496143890, 298511362 EFI35264.1 WP_008868397.1 430 430 yes 1889892 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1111106 Ancylobacter sp. FA202 Bacteria 517198805 WP_018387623.1 600 605 yes 1889893 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 891968 Anaerobaculum mobile DSM 13181 Bacteria UP000006061 390619746 AFM20893.1 fig|891968.3.peg.228 424 424 yes 1889894 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29471, 218491 Pectobacterium atrosepticum, Pectobacterium atrosepticum SCRI1043 Bacteria UP000028791, UP000007966 499404403, 81646547, 49609719 WP_011091870.1 Q6DAM0 THIC_PECAS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 604591 fig|218491.3.peg.3490 631 664 yes 1889895 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 999414 Fusobacterium nucleatum, Fusobacterium nucleatum subsp. animalis OT 420 Bacteria UP000004565 492647665, 371958848 EHO76549.1 WP_005910430.1 fig|999414.3.peg.1677 433 433 yes 1889896 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570, 571 Klebsiella oxytoca Bacteria UP000030350 515712542, 838825090, 828948658, 828930448 KLY07226.1, AKL23862.1, AKL06936.1 WP_017145142.1 626 631 yes 1889897 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1328324, 1438807, 1438704, 1400179, 1328426 Klebsiella pneumoniae, Klebsiella pneumoniae subsp. pneumoniae KPNIH27, Klebsiella pneumoniae UCI 62, Klebsiella pneumoniae BWH 46, Klebsiella pneumoniae UCI 34, Klebsiella pneumoniae BIDMC 40 Bacteria UP000036212, UP000027188, UP000027556, UP000027504, UP000020975, UP000017379 545106033, 640850875, 636446170, 635955649, 583472568, 554973096 AIA39979.1, KDM22864.1, KDH35821.1, EWD36522.1, ESL17805.1 WP_021469531.1 fig|441771.4.peg.1110, fig|441770.4.peg.1112, fig|413999.4.peg.1131 626 631 yes 1889898 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 530 530 yes 1889899 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265470 Desulfurispora thermophila Bacteria 516755795 WP_018085806.1 429 432 yes 1889900 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 83984, 410358 Methanocorpusculum labreanum, Methanocorpusculum labreanum Z Archaea UP000000365 500157907, 124362568 ABN06376.1 WP_011832577.1 A2SPX0 A2SPX0_METLZ fig|410358.8.peg.201 412 421 no 1889901 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1080187 Cupriavidus sp. UYPR2.512 Bacteria 517123487 WP_018312305.1 624 626 yes 1889902 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 263909, 1073574 Gordonia araii, Gordonia araii NBRC 100433 Bacteria UP000035088 494531118, 358245609 WP_007320569.1 fig|1073574.3.peg.368 555 560 yes 1889903 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 663, 314288 Vibrio alginolyticus, Vibrio alginolyticus 12G01 Bacteria UP000066605, UP000005966 491521180, 91188274 EAS74573.1 WP_005378810.1 fig|314288.3.peg.3732 640 646 yes 1889904 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1220534 Methanobacterium sp. Maddingley MBC34 Archaea 495787966, 410600705 EKQ55230.1 WP_008512545.1 K6TSB9 K6TSB9_9EURY 424 424 yes 1889905 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 816, 457387, 585544, 657309 Bacteroides sp. 1_1_30, Bacteroides sp. D22, Bacteroides xylanisolvens XB1A Bacteria UP000004085, UP000003817, UP000008795 495919099, 335938668, 298272667, 295083979 EGN00557.1, EFI14234.1 WP_008643678.1 fig|657309.4.peg.2437, fig|585544.3.peg.1536, fig|457387.3.peg.3314 565 565 yes 1889906 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 90245, 1401065 Oligella urethralis, Oligella urethralis DNF00040 Bacteria UP000029629 516658336, 690783489 KGF30396.1 WP_018025928.1 622 624 yes 1889907 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632, 992171 Yersinia pestis, Yersinia pestis PY-89 Bacteria UP000000815 UP000031825, UP000004729 488357737, 391653043 EIS90051.1 WP_002427122.1 fig|992173.3.peg.4071, fig|992157.3.peg.3912, fig|992167.3.peg.3761, fig|992159.3.peg.3720, fig|992133.3.peg.4185, fig|992146.3.peg.4076, fig|992147.3.peg.4083, fig|992170.3.peg.4053, fig|992171.3.peg.4041, fig|992174.3.peg.3910, fig|992139.3.peg.4156, fig|992166.3.peg.3685, fig|992160.3.peg.3896, fig|992178.3.peg.4106, fig|992162.3.peg.3907, fig|992136.3.peg.3935, fig|992185.3.peg.3774, fig|992150.3.peg.3812, fig|992176.3.peg.3875, fig|992154.3.peg.3836, fig|992137.3.peg.4106, fig|992177.3.peg.4111, fig|992145.3.peg.4172, fig|992149.3.peg.4129, fig|992144.3.peg.3952 442 457 yes 1889908 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 511 512 yes 1889909 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1768, 1299327 Mycobacterium kansasii, Mycobacterium kansasii 732 Bacteria UP000027649, UP000020425 738447634, 576420818 EUA14565.1 WP_036398823.1 541 544 yes 1889910 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 79329, 485918 Chitinophaga pinensis, Chitinophaga pinensis DSM 2588 Bacteria UP000002215 502444292, 256034575 ACU58119.1 WP_012788295.1 fig|485918.5.peg.2965 609 609 yes 1889911 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281158 Escherichia coli, Escherichia coli KOEGE 33 (68a) Bacteria UP000036210, UP000016294 545251130, 535400235 EQV41705.1 WP_021548903.1 626 631 yes 1889912 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 613198 Prochlorococcus sp. W7 Bacteria 518307499 WP_019477706.1 454 457 yes 1889913 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 658659 Erysipelotrichaceae bacterium 3_1_53 Bacteria UP000006223 496572390, 308915130 EFP60905.1 WP_009273508.1 337 337 yes 1889914 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263111 Sutterella wadsworthensis CAG:135 Environmental samples UP000018089 547260471, 524143962 WP_021995347.1 392 393 yes 1889915 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116118, 1116002 Escherichia coli, Escherichia coli BCE034_MS-14, Escherichia coli C-34666 Bacteria UP000036210, UP000012274, UP000012237 487476578, 476093364, 476091975 EMV16894.1, EMV15549.1 WP_001697304.1 fig|1116002.3.peg.5037, fig|1116118.3.peg.4849 626 631 yes 1889916 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1797, 1078020 Mycobacterium thermoresistibile, Mycobacterium thermoresistibile ATCC 19527 Bacteria UP000069654, UP000004915 490024160, 356479236 EHI12373.1 WP_003926637.1 fig|1078020.3.peg.3105 527 531 yes 1889917 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262865 Coraliomargarita sp. CAG:312 Environmental samples UP000017918 548261242, 524788067 WP_022478447.1 577 579 yes 1889918 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 142864, 56107 Cylindrospermum stagnale, Cylindrospermum stagnale PCC 7417 Bacteria UP000010475 505021130, 428259029 AFZ24979.1 WP_015208232.1 fig|56107.3.peg.3079 455 457 yes 1889919 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 224719 Methanobrevibacter sp. AbM4 Archaea UP000014066 511306036, 509083905 AGN16151.1 WP_016357854.1 R9SJ45 R9SJ45_9EURY 424 424 yes 1889920 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 450749 Veillonella sp. 6_1_27 Bacteria UP000005750 495878124, 294455863 EFG24227.1 WP_008602703.1 434 434 yes 1889921 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 457421 Clostridiales bacterium 1_7_47FAA Bacteria UP000004695 495992412, 239517016 EEQ56882.1 WP_008716991.1 fig|457421.5.peg.2200 434 435 yes 1889922 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 526 528 yes 1889923 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1223, 317619 Prochlorothrix hollandica, Prochlorothrix hollandica PCC 9006 Bacteria UP000034681 516317043, 815936620 KKJ01159.1 WP_017713737.1 458 462 yes 1889924 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 997335, 997336, 997337, 997338, 997339, 997340, 997341, 997342, 997343, 997344, 997345, 984250 Salmonella enterica, Salmonella enterica subsp. enterica serovar Newport str. VA_R100506907, Salmonella enterica subsp. enterica serovar Newport str. VA_R100512570, Salmonella enterica subsp. enterica serovar Newport str. VA_R100512572, Salmonella enterica subsp. enterica serovar Newport str. WA_14881, Salmonella enterica subsp. enterica serovar Newport str. WA_14882, Salmonella enterica subsp. enterica serovar Newport str. WA_14885, Salmonella enterica subsp. enterica serovar Newport str. WA_14900, Salmonella enterica subsp. enterica serovar Newport str. RI_10P068, Salmonella enterica subsp. enterica serovar Newport str. RI_10P069, Salmonella enterica subsp. enterica serovar Newport str. RI_10P078, Salmonella enterica subsp. enterica serovar Newport str. RI_10P079, Salmonella enterica subsp. enterica serovar Newport str. 637564_17 Bacteria UP000054489, UP000017263, UP000017421, UP000017355, UP000017501, UP000017345, UP000017422, UP000017529, UP000017368, UP000017489, UP000017488, UP000017432, UP000017603 554627492, 555753635, 553556880, 553554215, 553551616, 553545299, 553539652, 553537951, 553531632, 553529738, 553522198, 553519051, 553457469 ESO54947.1, ESC79173.1, ESC76585.1, ESC74063.1, ESC67930.1, ESC62406.1, ESC60744.1, ESC54555.1, ESC52698.1, ESC45261.1, ESC42175.1, ESB82160.1 WP_023165635.1 626 631 yes 1889925 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 574560, 1389415 Photorhabdus temperata, Photorhabdus temperata J3 Bacteria UP000017133 552944900, 550872630 ERT11800.1 WP_023045532.1 619 642 yes 1889926 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 420915 Pseudoalteromonas sp. Bsi20439 Bacteria UP000004843 495740507, 358041131 WP_008465086.1 fig|420915.3.peg.1070 646 650 yes 1889927 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1079800, 1211777 Rhizobium sp. CCGE 503, Rhizobium mesoamericanum STM3625 Bacteria UP000009319 494792893, 408748838 WP_007528301.1 fig|1211777.3.peg.3925 600 608 yes 1889928 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1465757 Peptoniphilus senegalensis Bacteria 517938259 WP_019108467.1 432 433 yes 1889929 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1229485 gamma proteobacterium WG36 Bacteria 516062168 WP_017492751.1 634 655 yes 1889930 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1207075 Pseudomonas sp. UW4 Bacteria UP000010397 504906104, 426265552 AFY17629.1 WP_015093206.1 fig|1207075.3.peg.438 627 629 yes 1889931 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29507, 437752 Leptospira kirschneri, Leptospira kirschneri serovar Mozdok Bacteria UP000030546 515122037, 704448728 KGR69200.1 WP_016750974.1 440 494 yes 1889932 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29575, 743973, 937774, 1091497 Taylorella equigenitalis, Taylorella equigenitalis ATCC 35865, Taylorella equigenitalis MCE9, Taylorella equigenitalis 14/56 Bacteria UP000053619, UP000003121, UP000007472 503287717, 695104810, 394349790, 317109397, 399115005 KGK33228.1, AFN35704.1, ADU92143.1 WP_013522378.1 fig|937774.3.peg.1176, fig|743973.3.peg.616 622 624 yes 1889933 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 935297 Vibrio cholerae, Vibrio cholerae LMA3984-4 Bacteria UP000028983, UP000006792 445993246, 327482970 AEA77377.1 WP_000071101.1 fig|935297.7.peg.61 640 646 yes 1889934 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35518, 1161902 Eubacterium nodatum, Eubacterium nodatum ATCC 33099 Bacteria UP000018868 736818650, 567339371 ETJ99551.1 WP_034820304.1 436 437 yes 1889935 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 303, 931281 Pseudomonas putida, Pseudomonas putida BIRD-1 Bacteria UP000054813, UP000008715 504405506, 313500901 ADR62267.1 WP_014592608.1 fig|931281.3.peg.4751 625 626 yes 1889936 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1161401 Maricaulis sp. JL2009 Bacteria 550949238 WP_022697633.1 624 631 yes 1889937 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1234592 Vibrio sp. 712i1 Bacteria 516229555 WP_017633518.1 640 646 yes 1889938 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169151 Micromonospora sp. CNB394 Bacteria 517614371 WP_018784579.1 530 530 yes 1889939 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 585348346 WP_024229963.1 626 631 yes 1889940 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151372 Clostridium difficile F501 Bacteria UP000015712 531517204 EQI02081.1 347 347 no 1889941 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1243180 Haloferax sp. BAB2207 Archaea 495882905, 432197228 ELK53626.1 WP_008607484.1 L5NSJ3 L5NSJ3_9EURY 437 465 yes 1889942 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626931, 742727 Bacteroides oleiciplenus, Bacteroides oleiciplenus YIT 12058 Bacteria UP000009872 496421540, 425727153 EKU90014.1 WP_009130387.1 fig|742727.4.peg.2916 572 572 yes 1889943 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 256839, 1353536 Shewanella decolorationis, Shewanella decolorationis S12 Bacteria UP000017548 555469019, 553947672 ESE41322.1 WP_023267002.1 675 717 yes 1889944 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 531, 313594 Polaribacter irgensii, Polaribacter irgensii 23-P Bacteria UP000003053 490707524, 88780723 EAR11902.1 WP_004570862.1 fig|1248440.3.peg.3626, fig|313594.3.peg.2142 619 619 yes 1889945 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 913241 Salmonella enterica subsp. enterica serovar Alachua str. R6-377 Bacteria UP000004642 353562868 EHC29367.1 fig|913241.3.peg.4447 420 422 yes 1889946 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 528348 Neisseria gonorrhoeae DGI2 Bacteria UP000002765 291011739 EFE03735.1 624 671 yes 1889947 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263066, 999406, 999404, 999408 Clostridium clostridioforme CAG:511, Clostridium clostridioforme 90A6, Clostridium clostridioforme 90A3, Clostridium clostridioforme 90A8 Environmental samples, Bacteria UP000018273, UP000013180, UP000013010, UP000013085 488658592, 480762024, 480674607, 480665146, 524831838 ENZ60873.1, ENZ18019.1, ENZ08884.1 WP_002587556.1 fig|999408.3.peg.5101, fig|999403.4.peg.371, fig|999404.4.peg.5286, fig|742735.4.peg.3579, fig|999405.4.peg.2628, fig|999409.3.peg.3618, fig|999406.3.peg.3786 468 496 yes 1889948 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 194867 Sphingomonas sp. ATCC 31555 Bacteria 518200728 WP_019370936.1 615 623 yes 1889949 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1447530 Pseudomonas aeruginosa, Pseudomonas aeruginosa 3575 Bacteria UP000065817, UP000023904 685892216, 611851775 EZO28146.1 WP_031633455.1 627 627 yes 1889950 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1121960 Halomonas zhanjiangensis Bacteria 517748813 WP_018919021.1 635 636 yes 1889951 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358 358 yes 1889952 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 253, 1218103 Chryseobacterium indologenes, Chryseobacterium indologenes NBRC 14944 Bacteria UP000037953, UP000019060 736733745, 573450740 WP_034737703.1 603 603 yes 1889953 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1329838 Enterobacter sp. BIDMC 26 Bacteria UP000022813 695753116, 578264935 EUM24910.1 WP_032679366.1 626 631 yes 1889954 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 79209, 768704 Desulfosporosinus meridiei, Desulfosporosinus meridiei DSM 13257 Bacteria UP000005262 504715585, 402253497 AFQ43772.1 WP_014902687.1 434 434 yes 1889955 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 420950, 1094980 Methanolobus psychrophilus, Methanolobus psychrophilus R15 Archaea UP000000459 504866335, 409169846 AFV23721.1 WP_015053437.1 K4MNV0 K4MNV0_9EURY 428 429 yes 1889956 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666686 Bacillus sp. 1NLA3E Bacteria UP000013300 505406394, 484576638 AGK53436.1 WP_015593496.1 594 594 yes 1889957 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 889251 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni 2008-894 Bacteria UP000065538, UP000004418 488980946, 380631428 EIB49622.1 WP_002891780.1 fig|889251.3.peg.20 430 430 yes 1889958 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 38288, 585529 Corynebacterium genitalium, Corynebacterium genitalium ATCC 33030 Bacteria UP000004208 491433726, 300533479 EFK54540.1 WP_005291519.1 592 595 yes 1889959 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1160718 Streptomyces auratus AGR0001 Bacteria UP000009036 396995350 EJJ06367.1 fig|1160718.3.peg.2848 291 294 yes 1889960 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1160718 Streptomyces auratus AGR0001 Bacteria UP000009036 396995198 EJJ06216.1 300 301 no 1889961 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173798 Salmonella enterica, Salmonella enterica subsp. enterica serovar Albany str. ATCC 51960 Bacteria UP000054489, UP000017480 555259658, 554360365 ESH97538.1 WP_023241985.1 626 631 yes 1889962 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151397 Clostridium difficile P6 Bacteria UP000015720 531622682 EQJ01864.1 147 147 no 1889963 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151397 Clostridium difficile P6 Bacteria UP000015720 531622683 EQJ01865.1 254 254 no 1889964 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61624, 1116391 Bacillus mucilaginosus, Paenibacillus mucilaginosus 3016 Bacteria UP000007523 504176356, 378567073 AFC27383.1 WP_014368280.1 597 607 yes 1889965 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305900 Endozoicomonas elysicola Bacteria UP000027997 658304863 KEI73256.1 575 584 yes 1889966 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1678, 1457184, 1161743, 469594 Bifidobacterium longum subsp. longum 72B, Bifidobacterium longum subsp. longum 44B, Bifidobacterium sp. 12_1_47BFAA Bacteria UP000028415, UP000004495, UP000003025 494118920, 665776160, 386415328, 316916951 KEY25987.1, EIJ29861.1, EFV38337.1 WP_007058699.1 fig|469594.3.peg.19, fig|1161743.3.peg.1469 635 917 yes 1889967 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56731 Rhizobium giardinii Bacteria 517140464 WP_018329282.1 601 611 yes 1889968 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 623, 766150 Shigella flexneri, Shigella flexneri K-315 Bacteria UP000029282, UP000005407 447199681, 391258588 EIQ17681.1 WP_001276937.1 fig|766150.3.peg.3876 626 631 yes 1889969 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1203261 Prochlorococcus sp. W2 Bacteria 518304159 WP_019474367.1 440 441 yes 1889970 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 622, 941429 Shigella dysenteriae, Shigella dysenteriae CDC 74-1112 Bacteria UP000003206 447199680, 320172744 EFW47978.1 WP_001276936.1 fig|622.8.peg.4737, fig|941429.3.peg.4761 626 631 yes 1889971 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1145195, 1145194, 1145193, 1145192, 1145191, 1145190, 1145189, 1145188, 1145187, 1145186, 1145185, 1145184, 1145183, 1145182, 1145181, 1145158 Neisseria meningitidis, Neisseria meningitidis NM3223, Neisseria meningitidis NM165, Neisseria meningitidis NM80, Neisseria meningitidis NM51, Neisseria meningitidis NM27, Neisseria meningitidis NM3164, Neisseria meningitidis NM3158, Neisseria meningitidis NM3144, Neisseria meningitidis NM3131, Neisseria meningitidis NM3222, Neisseria meningitidis NM3042, Neisseria meningitidis NM90, Neisseria meningitidis NM115, Neisseria meningitidis NM271, Neisseria meningitidis 2003051, Neisseria meningitidis 73704 Bacteria UP000050419, UP000013386, UP000013363, UP000013345, UP000013321, UP000013649, UP000013377, UP000013312, UP000013311, UP000013349, UP000013385, UP000013384, UP000013336, UP000013344, UP000013352, UP000013388, UP000013380 488185016, 485424056, 485423780, 485419755, 485417876, 485417254, 485412820, 485411354, 485411240, 485406147, 485404787, 485404306, 485399166, 485398273, 485397566, 485392287, 485348233 EOC80337.1, EOC80087.1, EOC76325.1, EOC74610.1, EOC74036.1, EOC69881.1, EOC68547.1, EOC68439.1, EOC63699.1, EOC62469.1, EOC62043.1, EOC57208.1, EOC56391.1, EOC55741.1, EOC50793.1, EOC09945.1 WP_002256224.1 fig|1145183.3.peg.2486, fig|1145185.3.peg.2572, fig|1077282.3.peg.2315, fig|1145194.3.peg.2474, fig|1079752.3.peg.1985, fig|1145190.3.peg.2561, fig|1145181.3.peg.2577, fig|1145184.3.peg.2647, fig|1055328.3.peg.2099, fig|1145189.3.peg.2472, fig|1145182.3.peg.2474, fig|1145187.3.peg.2448, fig|1145158.3.peg.2540, fig|1145193.3.peg.2417, fig|1145192.3.peg.2442, fig|1145191.3.peg.2503, fig|1145195.3.peg.2441, fig|1145186.3.peg.2536, fig|1079756.3.peg.2267, fig|1079755.3.peg.1819, fig|1145188.3.peg.2409 625 633 yes 1889972 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 119532, 756067 Microcoleus vaginatus, Microcoleus vaginatus FGP-2 Bacteria UP000004988 493685318, 333455536 EGK84182.1 WP_006635436.1 455 457 yes 1889973 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 269261, 749222 Nitratifractor salsuginis, Nitratifractor salsuginis DSM 16511 Bacteria UP000008633 503319938, 319419802 ADV46912.1 WP_013554599.1 fig|749222.3.peg.1660 452 455 yes 1889974 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 45851, 511680 Butyrivibrio crossotus, Butyrivibrio crossotus DSM 2876 Bacteria UP000006238 491792283, 292809718 EFF68923.1 WP_005602262.1 435 436 yes 1889975 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 581 583 no 1889976 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84595, 1112204 Gordonia polyisoprenivorans, Gordonia polyisoprenivorans VH2 Bacteria UP000009154 504124838, 375751051 AFA71871.1 WP_014358824.1 555 563 yes 1889977 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 366650, 981368 Xanthomonas alfalfae, Xanthomonas axonopodis pv. citrumelo F1 Bacteria UP000001276 503857005, 346650961 AEO43585.1 WP_014090999.1 fig|981368.3.peg.3356 623 625 yes 1889978 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294, 463794 Pseudomonas fluorescens, Pseudomonas fluorescens BBc6R8 Bacteria UP000060991, UP000005790 489302038, 562778979 ESW53107.1 WP_003209499.1 628 634 yes 1889979 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84595 Gordonia polyisoprenivorans Bacteria 519016556 WP_020172431.1 552 558 yes 1889980 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262918 Prevotella sp. CAG:1058 Environmental samples UP000018314 546366922, 523980024 WP_021851805.1 565 565 yes 1889981 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 518453572 WP_019623779.1 627 629 yes 1889982 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56448 Xanthomonas arboricola Bacteria UP000050499 515425081 WP_016902677.1 624 625 yes 1889983 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 552, 1255309 Erwinia amylovora, Erwinia amylovora Ea644 Bacteria UP000013125 490271839, 478726019 WP_004167972.1 fig|1255309.3.peg.256 631 644 yes 1889984 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 500638 Edwardsiella tarda ATCC 23685 Bacteria UP000003692 291092344 EFE24905.1 630 648 yes 1889985 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 457406 Micromonospora sp. M42 Bacteria UP000030692 759610066, 585247958 EWM67490.1 WP_043328264.1 201 201 no 1889986 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 457406 Micromonospora sp. M42 Bacteria UP000030692 585247959 EWM67491.1 317 317 yes 1889987 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1175306 Herbaspirillum sp. GW103 Bacteria UP000004194 495610172, 386432317 EIJ45145.1 WP_008334751.1 fig|1175306.3.peg.4451 636 637 yes 1889988 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 493915 Pseudoalteromonas sp. NJ631 Bacteria 515784792 WP_017217233.1 645 650 yes 1889989 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 102116, 111780 Stanieria cyanosphaera, Stanieria cyanosphaera PCC 7437 Bacteria UP000010473 505008274, 428271781 AFZ37722.1 WP_015195376.1 fig|111780.3.peg.4402 461 461 yes 1889990 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28035, 883164, 525377, 698737, 1034809 Staphylococcus lugdunensis, Staphylococcus lugdunensis ACS-027-V-Sch2, Staphylococcus epidermidis M23590, Staphylococcus lugdunensis HKU09-01, Staphylococcus lugdunensis N920143 Bacteria UP000057304, UP000001347, UP000004055, UP000002041, UP000011123 488390846, 410875682, 315495788, 289179540, 339893841 EKS23597.1, EFU84119.1, ADC86785.1 WP_002460231.1 fig|525377.3.peg.1414, fig|1034809.4.peg.629, fig|883164.3.peg.1287, fig|698737.3.peg.630 578 578 yes 1889991 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 146939, 640081 Azospira oryzae, Dechlorosoma suillum PS Bacteria UP000005633 504001543, 359353665 AEV24836.1 WP_014235537.1 fig|640081.3.peg.406 637 638 yes 1889992 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423, 1236548 Bacillus subtilis, Bacillus subtilis subsp. inaquosorum KCTC 13429 Bacteria UP000030083, UP000011182 489332397, 443347256 ELS61315.1 WP_003239647.1 fig|1236548.3.peg.2757 590 590 yes 1889993 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444241, 1444136, 1444218 Escherichia coli, Escherichia coli 7-233-03_S4_C2, Escherichia coli 1-392-07_S3_C1, Escherichia coli 1-250-04_S4_C1 Bacteria UP000036210, UP000027776, UP000027918, UP000024244 693137314, 660217537, 651827572, 611048315 KEN09303.1, KDX02205.1, EZJ51947.1 WP_032279831.1 626 631 yes 1889994 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 453852, 926559 Joostella marina, Joostella marina DSM 19592 Bacteria UP000004690 495886815, 386424409 EIJ38239.1 WP_008611394.1 618 618 yes 1889995 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 644968 Desulfovibrio sp. FW1012B Bacteria UP000004662 496470902, 357580963 EHJ46296.1 WP_009179747.1 418 437 no 1889996 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717, 698972 Corynebacterium diphtheriae, Corynebacterium diphtheriae INCA 402 Bacteria UP000033584, UP000007867 504068660, 371581673 AEX45339.1 WP_014302654.1 fig|698972.3.peg.33 592 599 yes 1889997 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 180, 1162668 Leptospirillum ferrooxidans, Leptospirillum ferrooxidans C2-3 Bacteria UP000007382 504262701, 383083791 WP_014449803.1 fig|1162668.3.peg.1948 461 464 yes 1889998 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 932213 Yersinia sp. M24tronco3 Bacteria UP000011072 497324919, 383293942 EIC82297.1 WP_009639132.1 fig|932213.3.peg.4546 634 655 yes 1889999 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262976 Sutterella sp. CAG:397 Environmental samples UP000018105 548024237, 524660500 WP_022373752.1 608 620 yes 1890000 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1764, 1391998 Mycobacterium avium, Mycobacterium avium subsp. paratuberculosis 08-8281 Bacteria UP000054432 564824834, 564165832 ETB08893.1 WP_023862980.1 131 132 no 1890001 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 710999 uncultured Vibrionales bacterium HF0010_22E23 Bacteria 297180832 ADI17038.1 444 444 no 1890002 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1150600 Arcticibacter svalbardensis MN12-7 Bacteria UP000014174 507723785 EOR94170.1 fig|1150600.3.peg.2639 436 436 no 1890003 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2176, 547558 Methanohalophilus mahii, Methanohalophilus mahii DSM 5219 Archaea UP000001059 502803370, 294496556, 292667555 ADE37404.1 WP_013038346.1, YP_003543049.1 D5E8B6 D5E8B6_METMS 10321527 406 414 no 1890004 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 517853408 WP_019023616.1 627 629 yes 1890005 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144664 Acinetobacter sp. CIP 102129 Bacteria UP000023777 490900415, 479938512 ENU85272.1 WP_004762352.1 fig|1144664.3.peg.2613 626 631 yes 1890006 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1211847 Xylella fastidiosa 6c Bacteria UP000018712 564927192 ETE22230.1 595 629 yes 1890007 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 688245 Comamonas testosteroni CNB-2 Bacteria UP000002360 262210128 ACY34226.1 fig|688245.4.peg.3700, fig|563045.3.peg.4134 625 657 yes 1890008 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1754, 1198630, 880478 Thermoanaerobacter thermohydrosulfuricus WC1, Thermoanaerobacter siderophilus SR4 Bacteria UP000013242, UP000005110 490539299, 475638540, 392291227 EMT38102.1, EIV99670.1 WP_004404444.1 fig|1198630.3.peg.2403, fig|880478.3.peg.1824 431 432 yes 1890009 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 376806 Bacteroides gallinarum Bacteria 517496144 WP_018666721.1 559 560 yes 1890010 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 530 530 yes 1890011 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53399, 582899 Hyphomicrobium denitrificans, Hyphomicrobium denitrificans ATCC 51888 Bacteria UP000002033 502979851, 299524143 ADJ22612.1 WP_013214827.1 fig|582899.7.peg.823 639 643 yes 1890012 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1223544 Gordonia sihwensis NBRC 108236 Bacteria UP000035083 441457406 fig|1223544.3.peg.3568 555 563 yes 1890013 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219, 59919 Prochlorococcus marinus, Prochlorococcus marinus subsp. pastoris str. CCMP1986 Bacteria UP000001026 499445774, 47606121, 33634385 WP_011133238.1 Q7UZP7 THIC_PROMP Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 566983 fig|59919.1.peg.1607 452 456 yes 1890014 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 246167 Vibrio crassostreae Bacteria UP000049932 515639845 WP_017072445.1 640 649 yes 1890015 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1172185 Nocardia sp. 348MFTsu5.1 Bacteria 518949437 WP_020105312.1 545 553 yes 1890016 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 243063 Thioalkalivibrio thiocyanodenitrificans Bacteria 517043821 WP_018232639.1 626 629 yes 1890017 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1142511 Wigglesworthia glossinidia endosymbiont of Glossina morsitans morsitans (Yale colony) Bacteria UP000009061 375158024 AFA41090.1 616 623 yes 1890018 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 1659716, 1354030 Enterobacter sp. GN02730, Enterobacter cloacae P101 Bacteria UP000035975, UP000018832 643378017, 829233668, 570290031 KLP40618.1, AHE72216.1 WP_025206413.1 626 631 yes 1890019 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 547045 Neisseria sicca ATCC 29256 Bacteria UP000005365 255048052 EET43516.1 317 484 no 1890020 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47920, 573060 Acidovorax delafieldii, Acidovorax delafieldii 2AN Bacteria UP000003856 492279472, 241364835 EER59808.1 WP_005797369.1 fig|573060.3.peg.2553 625 630 yes 1890021 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316, 1196835 Pseudomonas stutzeri, Pseudomonas stutzeri CCUG 29243 Bacteria UP000037382, UP000006063 504631801, 390981730 AFM31723.1 WP_014818903.1 fig|1196835.3.peg.472 627 627 yes 1890022 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 80679, 765912 Thioflavicoccus mobilis, Thioflavicoccus mobilis 8321 Bacteria UP000010816 505093547, 431829395 AGA90508.1 WP_015280649.1 fig|765912.4.peg.1701 627 630 yes 1890023 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 33952, 931626 Acetobacterium woodii, Acetobacterium woodii DSM 1030 Bacteria UP000007177 504121863, 375302112 AFA48246.1 WP_014355849.1 fig|931626.3.peg.1560 421 427 no 1890024 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65959, 945681 Acetobacter pomorum, Acetobacter pomorum DM001 Bacteria UP000029426, UP000018454 493058376, 685626972, 326697427 KGB24707.1, EGE49085.1 WP_006115101.1 606 625 yes 1890025 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33952, 931626 Acetobacterium woodii, Acetobacterium woodii DSM 1030 Bacteria UP000007177 504121864, 375302113 AFA48247.1 WP_014355850.1 fig|931626.3.peg.1561 421 426 yes 1890026 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 1261072 Bifidobacterium breve, Bifidobacterium breve JCP7499 Bacteria UP000029049, UP000016510 518557936, 542992592 ERI88125.1 WP_019728143.1 637 917 yes 1890027 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33044, 1094553 Bartonella doshiae, Bartonella doshiae NCTC 12862 Bacteria UP000008945 490993192, 395415514 EJF81948.1 WP_004854924.1 fig|1094553.3.peg.394 602 611 yes 1890028 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644, 1453502 Aeromonas hydrophila, Aeromonas veronii AD9 Bacteria UP000032249, UP000024306 759438636, 610713161 EZH82508.1 WP_043160890.1 641 659 yes 1890029 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 583 613 yes 1890030 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 755732 Fluviicola taffensis DSM 16823 Bacteria UP000007463 327320291 AEA44783.1 fig|755732.3.peg.2838 615 615 yes 1890031 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262936 Prevotella sp. CAG:873 Environmental samples UP000018078 548234921, 524758252 WP_022453398.1 571 571 yes 1890032 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281233, 1169361 Escherichia coli, Escherichia coli UMEA 3271-1, Escherichia coli KTE44 Bacteria UP000036210, UP000016306, UP000010583 486166295, 536025457, 430935565 ERB24475.1, ELC55875.1 WP_001529692.1 fig|1169361.3.peg.5177 626 631 yes 1890033 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 199737 uncultured candidate division WS3 bacterium Environmental samples 82523685 429 429 yes 1890034 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 92645, 864073 Herbaspirillum frisingense, Herbaspirillum frisingense GSF30 Bacteria UP000006772 493509274, 481869617 EOA04465.1 WP_006463641.1 636 637 yes 1890035 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 863643, 635013 Thermincola potens, Thermincola potens JR Bacteria UP000002377 502884637, 296030824 ADG81592.1 WP_013119613.1 fig|635013.3.peg.767 439 439 yes 1890036 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39956, 908290 Methylobacterium mesophilicum, Methylobacterium mesophilicum SR1.6/6 Bacteria UP000012488 498368191, 473437369 EMS44004.1 WP_010682347.1 fig|908290.3.peg.526 621 628 yes 1890037 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310759 Acinetobacter baumannii, Acinetobacter baumannii 573719 Bacteria UP000028632, UP000022150 691142397, 593641545 EXS21739.1 WP_032055614.1 621 625 yes 1890038 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 304736, 432331 Sulfurihydrogenibium yellowstonense, Sulfurihydrogenibium yellowstonense SS-5 Bacteria UP000005540 494810115, 237692370 EEP61355.1 WP_007545523.1 fig|432331.4.peg.116 448 453 yes 1890039 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 38293, 675817 Photobacterium damselae, Photobacterium damselae subsp. damselae CIP 102761 Bacteria UP000003579 491444559, 268163742 EEZ42238.1 WP_005302347.1 638 642 yes 1890040 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262824 Clostridium sp. CAG:58 Environmental samples UP000018263 547868158, 524510862 WP_022274438.1 435 435 yes 1890041 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 615 yes 1890042 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1226324 Blautia sp. KLE 1732 Bacteria UP000016485 542993809 ERI89215.1 436 441 yes 1890043 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487 Neisseria meningitidis Bacteria UP000050419 518103663 WP_019273871.1 523 524 yes 1890044 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158165 Thioalkalivibrio sp. ALMg11 Bacteria 517778068 WP_018948276.1 627 629 yes 1890045 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173, 436145, 338215, 1249484, 1049934, 1049819, 1049925, 1049905, 1049806, 1049903, 1049929, 1049795, 1049932, 1049920, 1001596, 1049940, 1193040, 1001598, 1001599, 1001597, 1193028, 1049938, 1049902, 1049906, 1049927, 1193060, 1193019, 1193039, 1049937, 1001587, 1049931, 1049924, 267671 Leptospira interrogans, Leptospira interrogans serovar Muenchen, Leptospira interrogans serovar Bratislava, Leptospira interrogans serovar Copenhageni str. M20, Leptospira interrogans str. MMD3731, Leptospira interrogans serovar Copenhageni str. HAI0188, Leptospira interrogans serovar Pomona str. UT364, Leptospira interrogans serovar Grippotyphosa str. UI 12769, Leptospira interrogans serovar Bataviae str. UI 08561, Leptospira interrogans serovar Grippotyphosa str. UI 08434, Leptospira interrogans serovar Pyrogenes str. R168, Leptospira interrogans serovar Autumnalis str. LP101, Leptospira interrogans str. L0996, Leptospira interrogans serovar Medanensis str. L0448, Leptospira interrogans serovar Djasiman str. LT1649, Leptospira interrogans str. UT126, Leptospira interrogans str. FPW1039, Leptospira interrogans serovar Copenhageni str. LT2050, Leptospira interrogans serovar Grippotyphosa str. LT2186, Leptospira interrogans serovar Canicola str. LT1962, Leptospira interrogans serovar Lora str. TE 1992, Leptospira interrogans str. UI 12758, Leptospira interrogans serovar Grippotyphosa str. UI 08368, Leptospira interrogans serovar Hebdomadis str. R499, Leptospira interrogans serovar Pyrogenes str. 2006006960, Leptospira santarosai str. HAI1594, Leptospira interrogans serovar Icterohaemorrhagiae str. Verdun LP, Leptospira interrogans str. Brem 329, Leptospira interrogans str. UI 12621, Leptospira interrogans serovar Pomona str. Pomona, Leptospira interrogans str. FPW2026, Leptospira interrogans serovar Pomona str. Kennewicki LC82-25, Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Bacteria UP000037872, UP000036291, UP000034903, UP000012186, UP000012148, UP000012105, UP000012152, UP000012140, UP000012133, UP000012155, UP000012123, UP000012096, UP000012125, UP000012102, UP000012150, UP000011968, UP000012164, UP000011778, UP000011776, UP000011781, UP000011754, UP000001340, UP000001331, UP000001149, UP000001146, UP000002842, UP000002846, UP000002847, UP000006324, UP000006266, UP000006959, UP000006994, UP000007037 488000514, 829079675, 822489988, 476491482, 464361351, 464337279, 464311199, 464289050, 464273454, 464266575, 464259724, 464246992, 464232505, 464221981, 464161399, 463282494, 462453150, 456982866, 456967684, 456824871, 455791378, 410775746, 410769413, 410766735, 410753968, 410432114, 410366635, 410345407, 409961506, 409945932, 400361303, 400327899, 59798773 KLO77123.1, AKH79079.1, EMY51835.1, EMO36989.1, EMO19588.1, EMO01200.1, EMN84878.1, EMN73064.1, EMN67820.1, EMN62461.1, EMN52588.1, EMN42082.1, EMN33555.1, EMM89142.1, EMJ52798.1, EMJ33969.1, EMG19332.1, EMG09017.1, EMF73297.1, EMF43194.1, EKR55737.1, EKR44655.1, EKR37418.1, EKR15626.1, EKP76472.1, EKP22026.1, EKO96503.1, EKO25251.1, EKN95946.1, EJP17270.1, EJO80139.1 WP_002072371.1 Q72NZ8 THIC_LEPIC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 661326 fig|1291365.3.peg.115, fig|996832.3.peg.3933, fig|996827.3.peg.2004, fig|1001598.3.peg.2040, fig|267671.5.peg.3216, fig|1291308.3.peg.4706, fig|996821.3.peg.812, fig|996862.3.peg.1823, fig|1001597.3.peg.2122, fig|996838.3.peg.1209, fig|1291318.3.peg.2495, fig|1001602.3.peg.4185, fig|996814.3.peg.1865, fig|996824.3.peg.2063, fig|996854.3.peg.1358, fig|1049802.3.peg.1366, fig|1291316.3.peg.4373, fig|996845.3.peg.3327, fig|1049929.3.peg.317, fig|996860.3.peg.2153, fig|996828.3.peg.1571, fig|1291342.3.peg.1203, fig|1049940.3.peg.2067, fig|1291324.3.peg.2242, fig|996831.3.peg.2209, fig|1193040.3.peg.3535, fig|1291321.3.peg.3385, fig|1193029.3.peg.5343, fig|1291340.3.peg.2910, fig|1049924.3.peg.5530, fig|1049803.3.peg.305, fig|1049805.3.peg.3875, fig|267671.1.peg.2601, fig|996835.3.peg.2323, fig|1049921.3.peg.4152, fig|1291343.3.peg.2225, fig|1049909.3.peg.1075, fig|1291366.3.peg.3261, fig|1291337.3.peg.3384, fig|996843.3.peg.1433, fig|996811.3.peg.1597, fig|996861.3.peg.2077, fig|996834.3.peg.1129, fig|1291307.3.peg.409, fig|1291354.3.peg.2987, fig|1291309.3.peg.901, fig|996837.3.peg.916, fig|1049903.3.peg.912, fig|1193014.3.peg.2329, fig|1049922.3.peg.3267, fig|1291335.3.peg.1751, fig|1049821.3.peg.807, fig|1291334.3.peg.3558, fig|1291357.3.peg.1373, fig|1291315.3.peg.605, fig|1193042.3.peg.3836, fig|1291361.3.peg.4894, fig|1218574.3.peg.2494, fig|1049819.3.peg.4049, fig|1049913.3.peg.201, fig|1240691.3.peg.2583, fig|996856.3.peg.2457, fig|1049936.3.peg.2259, fig|996829.3.peg.2846, fig|1291330.3.peg.1826, fig|1291341.3.peg.296, fig|1049907.3.peg.640, fig|1001599.3.peg.942, fig|1291364.3.peg.3901, fig|1049795.3.peg.3497, fig|996839.3.peg.1389, fig|1049932.3.peg.1014, fig|1049807.3.peg.4745, fig|1049920.3.peg.1374, fig|996858.3.peg.1945, fig|1291344.3.peg.1842, fig|1193060.3.peg.2208, fig|1291351.3.peg.2932, fig|1049806.3.peg.1973, fig|1291355.3.peg.4501, fig|1291353.3.peg.2073, fig|996857.3.peg.2288, fig|1291320.3.peg.3717, fig|1291339.3.peg.215, fig|1291328.3.peg.562, fig|996846.3.peg.3151, fig|996850.3.peg.883, fig|1291356.3.peg.3862, fig|996851.3.peg.2089, fig|1291347.3.peg.478, fig|1001986.3.peg.3725, fig|996840.3.peg.1766, fig|1049926.3.peg.2337, fig|1193028.3.peg.4647, fig|1291348.3.peg.2896, fig|1085543.3.peg.2547, fig|1291336.3.peg.678, fig|996842.3.peg.1990, fig|996847.3.peg.962, fig|996863.3.peg.991, fig|996825.3.peg.2512, fig|1291319.3.peg.2338, fig|1291352.3.peg.2231, fig|996853.3.peg.2085, fig|1291333.3.peg.1057, fig|996809.3.peg.3370, fig|1291358.3.peg.2032, fig|1291325.3.peg.399, fig|996849.3.peg.1904, fig|1049801.3.peg.1413, fig|996822.3.peg.1419, fig|1291331.3.peg.2205, fig|1291346.3.peg.4439, fig|1001987.3.peg.909, fig|1291329.3.peg.736, fig|1291359.3.peg.4108, fig|1291345.3.peg.2419, fig|1240692.3.peg.572, fig|1291317.3.peg.3348, fig|996830.3.peg.1058, fig|996836.3.peg.3269, fig|1049935.3.peg.749, fig|996823.3.peg.410, fig|1291360.3.peg.715, fig|996816.3.peg.4453, fig|1001587.6.peg.128, fig|1291332.3.peg.406, fig|1049931.3.peg.1146, fig|1049928.3.peg.624, fig|1193019.3.peg.2896, fig|1001591.3.peg.1477, fig|1085542.3.peg.1104, fig|996859.3.peg.129, fig|1049938.3.peg.3667, fig|1291327.3.peg.3107, fig|996848.3.peg.442, fig|1049905.3.peg.1563, fig|1049820.3.peg.898, fig|1049908.3.peg.769, fig|1291338.3.peg.3171, fig|1049937.3.peg.5644, fig|996833.3.peg.616, fig|1193039.3.peg.3102, fig|1049902.3.peg.1103 441 495 yes 1890046 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1124968 Salmonella enterica, Salmonella enterica subsp. enterica serovar Stanley str. ATCC 7308 Bacteria UP000054489, UP000017313 554959522, 554105543 ESF46980.1 WP_023204412.1 626 631 yes 1890047 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 346045 Amycolatopsis benzoatilytica Bacteria 522153199 WP_020664407.1 544 547 yes 1890048 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1403540 Halomonas sp. BCO4 Bacteria UP000019279 759813110, 584387177 EWH03889.1 WP_043510175.1 629 629 yes 1890049 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 847, 556268 Oxalobacter formigenes, Oxalobacter formigenes HOxBLS Bacteria UP000003973 492538922, 229378354 EEO28445.1 WP_005878158.1 fig|556268.6.peg.2020 636 637 yes 1890050 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40990, 928724 Saccharomonospora glauca, Saccharomonospora glauca K62 Bacteria UP000005087 491608937, 384523483 EIF00679.1 WP_005466495.1 543 545 yes 1890051 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 584, 1125694 Proteus mirabilis, Proteus mirabilis WGLW6 Bacteria UP000033762, UP000005363 490369492, 404596810 EKA97328.1 WP_004249138.1 fig|1125694.3.peg.2783 620 650 yes 1890052 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173805 Salmonella enterica, Salmonella enterica subsp. enterica serovar Cerro str. 5569 Bacteria UP000054489, UP000018569 565889480, 564582193 ETC77016.1 WP_023970599.1 626 631 yes 1890053 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 88274 delta proteobacterium NaphS2 Bacteria UP000003834 493470443, 300441307 EFK05676.1 WP_006425526.1 427 427 yes 1890054 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 592 592 yes 1890055 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1120045, 990285 Rhizobium grahamii, Rhizobium sp. CCGE 502 Bacteria UP000014411 514395835, 512775109 EPE95917.1 WP_016556695.1 601 608 yes 1890056 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 654, 1073385 Aeromonas veronii, Aeromonas veronii AMC35 Bacteria UP000051545, UP000005385 491500072, 404627782 EKB24582.1 WP_005357766.1 fig|1073385.3.peg.860 645 663 yes 1890057 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1031, 870187 Thiothrix nivea, Thiothrix nivea DSM 5205 Bacteria UP000005317 488797384, 386422061 EIJ35896.1 WP_002709790.1 626 629 yes 1890058 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1365187, 1211705 Vibrio parahaemolyticus, Vibrio parahaemolyticus CFSAN001595, Vibrio parahaemolyticus BB22OP Bacteria UP000028114, UP000027728, UP000010823 505110403, 651242228, 432509788 KDV00181.1, AGB11305.1 WP_015297505.1 fig|1211705.3.peg.2909 640 646 yes 1890059 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 1334630 Enterobacter cloacae, Enterobacter cloacae EC_38VIM1 Bacteria UP000036177, UP000016565 544826986, 528777816 EPY94041.1 WP_021242962.1 626 631 yes 1890060 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1249627 Thiorhodococcus sp. AK35 Bacteria UP000019460 760064916, 589834923 EXJ17259.1 WP_043747772.1 627 630 yes 1890061 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 368405, 1127672 Glaciecola chathamensis, Glaciecola chathamensis S18K6 Bacteria UP000006320 495266608, 410137187 WP_007991363.1 fig|1127672.3.peg.4046 620 626 yes 1890062 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2173, 1263088 Methanobrevibacter smithii, Methanobrevibacter smithii CAG:186 Archaea UP000018189 518092254, 524835682 WP_019262462.1 R7PYK6 R7PYK6_9EURY 432 432 yes 1890063 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1150997, 1094979 Marinobacter manganoxydans, Marinobacter manganoxydans MnI7-9 Bacteria UP000003208 495446140, 357227313 EHJ05775.1 WP_008170834.1 fig|1094979.3.peg.875 621 625 yes 1890064 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 253839 Streptomyces sp. C Bacteria UP000005763 302444516 EFL16332.1 565 566 yes 1890065 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 576, 1667327 Klebsiella sp., Klebsiella quasipneumoniae subsp. quasipneumoniae Bacteria UP000019765 635563378, 591283954 626 687 yes 1890066 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28141, 1208592 Cronobacter sakazakii, Cronobacter sakazakii 680 Bacteria UP000027472, UP000009360 495171577, 816220225, 426324691 AKE93613.1 WP_007896373.1 fig|1159614.3.peg.165, fig|1208592.3.peg.2514 626 633 yes 1890067 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1458357 Burkholderia sp. MP-1 Bacteria UP000025405 737538291, 620640301 KAK42419.1 WP_035511643.1 642 643 yes 1890068 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28133, 1073366 Prevotella nigrescens, Prevotella sp. CC14M Bacteria UP000018727 565842837, 564728139 ETD28110.1 WP_023926028.1 526 526 yes 1890069 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 715451 Alteromonas sp. enrichment culture clone SN2 Environmental samples UP000000683 503552018, 332995127 AEF05182.1 WP_013786094.1 fig|715451.3.peg.3709 639 645 yes 1890070 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1131276 alpha proteobacterium SCGC AB-629-G21 Bacteria 516681496 WP_018039384.1 369 369 no 1890071 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28108, 1004787 Alteromonas macleodii, Alteromonas macleodii str. 'Balearic Sea AD45' Bacteria UP000031168, UP000006308 504790825, 407289278 AFT93590.1 WP_014977927.1 fig|1004787.3.peg.105 630 636 yes 1890072 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 676, 1336753 Vibrio fluvialis, Vibrio fluvialis I21563 Bacteria UP000051756, UP000014855 521102767, 519728372 EPP19766.1 WP_020433610.1 640 649 yes 1890073 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570156, 1452721 Pseudoalteromonas sp. LMEB 39, Pseudoalteromonas lipolytica SCSIO 04301 Bacteria UP000050378, UP000021443 739100759, 584420240 EWH05829.1 WP_036971427.1 645 650 yes 1890074 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 126385, 1256988, 1256989 Providencia alcalifaciens, Providencia alcalifaciens 205/92, Providencia alcalifaciens R90-1475 Bacteria UP000022311, UP000020208 739092505, 577073465, 577072583 EUD09726.1, EUD08979.1 WP_036963423.1 623 655 yes 1890075 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1150600 Arcticibacter svalbardensis MN12-7 Bacteria UP000014174 507723786 EOR94171.1 fig|1150600.3.peg.2640 186 186 no 1890076 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 985010 Pseudomonas sp. TJI-51 Bacteria UP000004224 497367123, 324103585 EGC00891.1 WP_009681336.1 625 626 yes 1890077 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 657322 Faecalibacterium prausnitzii SL3/3 Bacteria UP000007059 295103431 435 436 yes 1890078 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76761 Pseudomonas veronii Bacteria UP000051329 516460944 WP_017849782.1 627 629 yes 1890079 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1235798 Dorea sp. 5-2 Bacteria UP000014211 510888357, 507816195 EOS72680.1 WP_016222003.1 fig|1235798.3.peg.5673 348 376 no 1890080 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053189 Bacillus cereus, Bacillus cereus BAG5X1-1 Bacteria UP000036076, UP000006600 488127622, 401145705 EJQ53228.1 WP_002198830.1 fig|1053189.3.peg.273 586 586 yes 1890081 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34038, 745277 Rahnella aquatilis, Rahnella aquatilis CIP 78.65 = ATCC 33071 Bacteria UP000028611 505737363, 668990385, 371590267 KFD02184.1, AEX53997.1 WP_015699033.1 fig|745277.3.peg.4066 634 654 yes 1890082 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406 Paenibacillus polymyxa Bacteria UP000031922 518515935 WP_019686142.1 591 614 yes 1890083 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262753 Bacteroides sp. CAG:927 Environmental samples UP000017907 514416222, 514045747 WP_016564054.1 568 568 yes 1890084 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29442 Pseudomonas tolaasii Bacteria 515539577 WP_016972630.1 627 629 yes 1890085 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 913865 Desulfosporosinus sp. OT Bacteria UP000004928 344328050 EGW39451.1 fig|913865.3.peg.2408 421 421 yes 1890086 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 662598 Neisseria meningitidis alpha14 Bacteria UP000002054 254667691 fig|662598.3.peg.149 625 633 yes 1890087 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 491921 Megamonas rupellensis Bacteria 517829861 WP_019000069.1 433 434 yes 1890088 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 3055 Chlamydomonas reinhardtii Plants UP000006906 UP000006906 159479348, 158274123 EDO99907.1 XP_001697755.1 162 256 no 1890089 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 340188, 1094506, 1410916, 1410919, 1410922, 1410918, 1410924, 1410920, 1410923, 1410925, 1410931, 1410921, 1410930, 1410927, 1410917, 1410928, 1410926, 1410929, 1124928 Salmonella enterica, Salmonella enterica subsp. enterica serovar Cerro, Salmonella enterica subsp. enterica serovar Cerro FSL R8-0235, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001588, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001589, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001670, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001587, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001673, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001590, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001671, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001679, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001697, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001669, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001692, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001681, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001674, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001690, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001680, Salmonella enterica subsp. enterica serovar Cerro str. CFSAN001691, Salmonella enterica subsp. enterica serovar Cerro str. 818 Bacteria UP000054489, UP000036385, UP000025412, UP000018567, UP000018552, UP000018565, UP000018529, UP000018575, UP000018558, UP000018531, UP000018577, UP000018570, UP000018528, UP000018562, UP000018541, UP000018539, UP000018560, UP000018561, UP000018546, UP000017473 555250506, 856822820, 627373382, 564560249, 564558270, 564551328, 564544325, 564536133, 564523360, 564521770, 564521651, 564511897, 564511480, 564501164, 564500621, 564492632, 564486111, 564478206, 564475183, 554286965 KMN25425.1, KCU90680.1, ETC56475.1, ETC54558.1, ETC47820.1, ETC41122.1, ETC33139.1, ETC20533.1, ETC18978.1, ETC18863.1, ETC09357.1, ETC08953.1, ETB98917.1, ETB98388.1, ETB90622.1, ETB84232.1, ETB76445.1, ETB73504.1, ESH22370.1 WP_023234037.1 626 631 yes 1890090 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1329895, 1096930 Novosphingobium lindaniclasticum, Novosphingobium sp. LE124 Bacteria UP000015527 544815739, 530277497 EQB19647.1 WP_021232143.1 612 634 yes 1890091 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263048 Bacteroides intestinalis CAG:315 Environmental samples UP000018219 548170072, 524683942 WP_022391839.1 574 574 yes 1890092 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 444922 Psychromonas ossibalaenae Bacteria 518446750 WP_019616957.1 642 658 yes 1890093 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 693985 Pseudomonas savastanoi pv. savastanoi NCPPB 3335 Bacteria UP000005729 298160497 EFI01520.1 625 627 yes 1890094 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 668, 312309 Aliivibrio fischeri, Vibrio fischeri ES114 Bacteria UP000035964, UP000000537 499580130, 59710639, 835721825, 59478740, 75431916 KLU79014.1, AAW84527.1 WP_011260913.1, YP_203415.1 Q5E8W9 THIC_VIBF1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 942877 fig|312309.11.peg.34 640 644 yes 1890095 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717 Corynebacterium diphtheriae Bacteria UP000033584 515263102 WP_016830275.1 592 599 yes 1890096 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 509 509 yes 1890097 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375, 476282 Bradyrhizobium japonicum, Bradyrhizobium japonicum SEMIA 5079 Bacteria UP000030904, UP000025221 746086027, 627784556 AHY53773.1 WP_039153095.1 623 632 yes 1890098 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1049910 Leptospira interrogans serovar Icterohaemorrhagiae str. Verdun HP Bacteria UP000012092 464317624 EMO05116.1 154 154 no 1890099 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39152, 267377 Methanococcus maripaludis, Methanococcus maripaludis S2 Archaea UP000000590 499483491 WP_011170131.1 P61428 THIC_METMP Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 532373 fig|267377.1.peg.187 426 426 yes 1890100 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1242992 Leptospira sp. B5-022 Bacteria UP000011981 463332467 EMJ97379.1 fig|1242992.3.peg.3399 528 529 yes 1890101 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 530 530 yes 1890102 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28448, 1296990 Gluconacetobacter xylinus, Gluconacetobacter xylinus E25 Bacteria UP000019231 645068631, 582023541 AHI26883.1 WP_025439710.1 605 613 yes 1890103 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 1144335, 1144334 Pseudomonas sp. GM67, Pseudomonas sp. GM60 Bacteria UP000007281, UP000007508 495303144, 398201065, 398196696 EJM87956.1, EJM83695.1 WP_008027894.1 fig|1144335.3.peg.2825, fig|1144334.3.peg.2104 627 629 yes 1890104 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287182 Mesorhizobium sp. L48C026A00 Bacteria UP000019863 563192190 ESZ15243.1 512 516 yes 1890105 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644, 1416915, 1419584, 1418107, 1418110, 1288394 Aeromonas hydrophila, Aeromonas hydrophila NJ-35, Aeromonas hydrophila J-1, Aeromonas hydrophila pc104A, Aeromonas hydrophila AL09-71, Aeromonas hydrophila ML09-119 Bacteria UP000032249, UP000035432, UP000031528, UP000023727, UP000023719, UP000014069 511288951, 827374297, 748235715, 615568199, 613731280, 507219702 AKJ36484.1, AJE38186.1, AHX67761.1, AHX30966.1, AGM42239.1 WP_016349218.1 fig|1288394.3.peg.458 645 663 yes 1890106 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1330036 Osedax symbiont Rs1 Bacteria UP000014822 518638333, 515419199 EPJ47784.1 WP_019808487.1 629 631 yes 1890107 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 837, 1321823, 1227269, 1227271 Porphyromonas gingivalis, Porphyromonas gingivalis W4087, Porphyromonas gingivalis F0568, Porphyromonas gingivalis F0570 Bacteria UP000028798, UP000016650, UP000016641, UP000016630 545423619, 543984594, 543958578, 543958190 ERJ88020.1, ERJ68674.1, ERJ68311.1 WP_021662296.1 587 587 yes 1890108 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 491919 Brachymonas chironomi Bacteria 517545241 WP_018715449.1 618 630 yes 1890109 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262954 Ruminococcus sp. CAG:330 Environmental samples UP000018377 548189265, 524705106 WP_022410106.1 442 443 yes 1890110 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1268072 Paenibacillus sabinae T27 Bacteria UP000019772 605574967 AHV97634.1 274 274 yes 1890111 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1268072 Paenibacillus sabinae T27 Bacteria UP000019772 605574966 AHV97633.1 294 294 no 1890112 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54571, 953739 Streptomyces venezuelae, Streptomyces venezuelae ATCC 10712 Bacteria UP000058026, UP000006854 504847804, 328883754 WP_015034906.1 594 597 yes 1890113 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28091, 1051985 Neisseria weaveri, Neisseria weaveri LMG 5135 Bacteria UP000004938 490412481, 343966845 EGV35097.1 WP_004285131.1 fig|1051985.3.peg.2141 621 624 yes 1890114 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29430, 1217986 Acinetobacter haemolyticus, Acinetobacter haemolyticus NIPH 261 Bacteria UP000013208 491229670, 480084160 ENW22668.1 WP_005087925.1 fig|1217986.3.peg.62 626 631 yes 1890115 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 516388856 WP_017778532.1 645 663 yes 1890116 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 118562, 634502, 696747 Arthrospira platensis, Arthrospira platensis str. Paraca, Arthrospira platensis NIES-39 Bacteria UP000010114, UP000006803 493668657, 647980376, 291565864 KDR57391.1 WP_006618999.1 460 462 yes 1890117 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111504 Bartonella birtlesii Bacteria 515763723 WP_017196323.1 601 610 yes 1890118 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1131286 zeta proteobacterium SCGC AB-137-J06 Bacteria 517095446 WP_018284264.1 272 272 no 1890119 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 614, 1346614 Serratia liquefaciens, Serratia liquefaciens ATCC 27592 Bacteria UP000033102, UP000014922 525775061, 523444656 AGQ33566.1 WP_020828732.1 633 647 yes 1890120 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 119912, 997330, 938142, 904139, 321314 Salmonella enterica, Salmonella enterica subsp. enterica serovar Choleraesuis, Salmonella enterica subsp. enterica serovar Choleraesuis str. 0006, Salmonella enterica subsp. enterica serovar Choleraesuis str. ATCC 10708, Salmonella enterica subsp. enterica serovar Choleraesuis str. SCSA50, Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67 Bacteria UP000054489, UP000028944, UP000017567, UP000017553, UP000003971, UP000000538 486186304, 674192474, 554313161, 554292381, 322717112, 62130248, 75479219 AIK95069.1, ESH49365.1, ESH28609.1, EFZ08683.1, AAX67951.1 WP_001541272.1 Q57H61 THIC_SALCH Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 902472 fig|904139.4.peg.2909, fig|321314.4.peg.3770 626 631 yes 1890121 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 667127 Klebsiella pneumoniae, Klebsiella pneumoniae subsp. rhinoscleromatis ATCC 13884 Bacteria UP000036212, UP000003765 490248171, 259038890 EEW40058.1 WP_004146299.1 fig|667127.3.peg.5011 626 631 yes 1890122 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 541095 Corynebacterium lubricantis Bacteria 517108394 WP_018297212.1 571 576 yes 1890123 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 85558, 698760 Streptomyces turgidiscabies, Streptomyces turgidiscabies Car8 Bacteria UP000066359, UP000010931 493417959, 440283638 ELP70876.1 WP_006373815.1 fig|698760.3.peg.500 600 606 yes 1890124 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 717609, 608506 Caldicellulosiruptor obsidiansis, Caldicellulosiruptor obsidiansis OB47 Bacteria UP000000347 503054709, 302573888 ADL41679.1 WP_013289685.1 fig|608506.3.peg.384 419 420 yes 1890125 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1344585, 641526 Winogradskyella psychrotolerans, Winogradskyella sp. RS-3 Bacteria UP000014962 527071513, 523604000 EPR72717.1 WP_020895242.1 619 619 yes 1890126 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 641107 Clostridium sp. DL-VIII Bacteria UP000005106 496459686, 357169675 EHI97849.1 WP_009168531.1 436 436 yes 1890127 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36861 Thiobacillus denitrificans Bacteria UP000064243 516743889 WP_018078303.1 646 647 yes 1890128 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116096, 1116100 Escherichia coli, Escherichia coli p0305293.8, Escherichia coli p0305293.12 Bacteria UP000036210, UP000012399, UP000012368 487394070, 477401379, 477371373 ENG68091.1, ENG39602.1 WP_001665095.1 fig|1116100.3.peg.4668, fig|1116096.3.peg.4731 626 631 yes 1890129 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550 563 yes 1890130 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1496, 1215061, 1225722, 1215060, 1215059 Clostridium difficile, Clostridium difficile E10, Clostridium difficile E1, Clostridium difficile T20, Clostridium difficile T5 Bacteria UP000058232, UP000018043, UP000018272, UP000018146, UP000018344 497591367, 549292637, 549285382, 549281703, 549281501 WP_009905551.1 433 433 yes 1890131 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992172, 992169, 992164, 992159, 992158, 992155 Yersinia pestis, Yersinia pestis PY-90, Yersinia pestis PY-76, Yersinia pestis PY-64, Yersinia pestis PY-58, Yersinia pestis PY-56, Yersinia pestis PY-53 Bacteria UP000000815 UP000031825, UP000003564, UP000005986, UP000004572, UP000005994, UP000005712, UP000003767 488351595, 391658695, 391645717, 391611798, 391591913, 391581477, 391566278 EIS95074.1, EIS83566.1, EIS53938.1, EIS36420.1, EIS27355.1, EIS14289.1 WP_002420980.1 207 226 no 1890132 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 581 582 yes 1890133 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 427078 Salsuginibacillus kocurii Bacteria 517754102 WP_018924310.1 593 594 yes 1890134 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1381111 Corynebacterium pseudodiphtheriticum 090104 Bacteria UP000016653 543387143 ERJ45301.1 605 613 yes 1890135 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54005, 908338 Peptoniphilus harei, Peptoniphilus harei ACS-146-V-Sch2b Bacteria UP000003705 492764758, 312845435 EFR32830.1 WP_005956909.1 432 433 yes 1890136 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 32008, 640510 Burkholderia sp. CCGE1001 Bacteria UP000007095 503354331, 323383693 ADX55784.1 WP_013588992.1 fig|640510.3.peg.5213 642 643 yes 1890137 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169855 Rhodobacteraceae bacterium PD-2 Bacteria UP000023196 564609738, 563421301 ETA50314.1 WP_023850968.1 597 600 yes 1890138 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1402, 1126218 Bacillus licheniformis, Bacillus licheniformis WX-02 Bacteria UP000036721, UP000003265 489272264, 383438088 EID45863.1 WP_003179984.1 fig|1126218.3.peg.1121 591 591 yes 1890139 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1496, 1151411 Clostridium difficile, Clostridium difficile P29 Bacteria UP000058232, UP000015800 545047124, 531680065 EQJ57524.1 WP_021421563.1 433 433 yes 1890140 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 506534 Rheinheimera sp. A13L Bacteria UP000004282 496176254, 335878006 EGM75954.1 WP_008900761.1 635 650 yes 1890141 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1238222 Vibrio parahaemolyticus, Vibrio parahaemolyticus VPTS-2010 Bacteria UP000028114, UP000024521 686214084, 589861426 EXJ38124.1 WP_031815741.1 640 646 yes 1890142 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 13435255 AAK26130.1 550 628 yes 1890143 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 1297579, 469604 Fusobacterium nucleatum, Fusobacterium nucleatum CC53, Fusobacterium sp. 3_1_36A2 Bacteria UP000011978, UP000016231 496075551, 465145560, 256719711 EMP16897.1, EEU33266.1 WP_008800058.1 fig|469604.3.peg.748 433 433 yes 1890144 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 293085, 1218591 Leptospira genomosp. 3, Leptospira vanthielii serovar Holland str. Waz Holland Bacteria UP000012227 489066355, 476503333 EMY71626.1 WP_002976353.1 502 504 yes 1890145 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1054217 Thermoplasmatales archaeon BRNA1 Archaea UP000012076 505305927, 472832775 AGI48512.1 WP_015493029.1 M4YQ41 M4YQ41_9EURY 437 440 yes 1890146 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 627192 Sphingobium sp. SYK-6 Bacteria UP000001275 503840680, 345135413 WP_014074674.1 fig|627192.4.peg.495 617 624 yes 1890147 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 442 442 yes 1890148 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 142461, 870968 Vibrio ichthyoenteri, Vibrio ichthyoenteri ATCC 700023 Bacteria UP000004605 493764515, 342801881 EGU37333.1 WP_006713148.1 640 645 yes 1890149 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 885581, 646529 Desulfosporosinus acidophilus, Desulfosporosinus acidophilus SJ4 Bacteria UP000002892 504640350, 391355755 AFM41454.1 WP_014827452.1 422 432 yes 1890150 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1124991 Morganella morganii subsp. morganii KT Bacteria UP000011834 455419417 AGG29747.1 620 649 yes 1890151 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 885581, 646529 Desulfosporosinus acidophilus, Desulfosporosinus acidophilus SJ4 Bacteria UP000002892 504640351, 391355756 AFM41455.1 WP_014827453.1 420 433 yes 1890152 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 514865841 WP_016604463.1 226 245 no 1890153 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1496, 1151389, 1151382, 1151381, 1151358, 1151356, 1151310, 1151264 Clostridium difficile, Clostridium difficile Y358, Clostridium difficile Y231, Clostridium difficile Y215, Clostridium difficile DA00275, Clostridium difficile DA00261, Clostridium difficile 840, Clostridium difficile CD41 Bacteria UP000058232, UP000015652, UP000015737, UP000015843, UP000015665, UP000015833, UP000015669, UP000015835 544964942, 531588721, 531559424, 531552221, 531473307, 531466277, 531304672, 531139616 EQI69655.1, EQI41611.1, EQI34908.1, EQH61600.1, EQH54788.1, EQF99860.1, EQE43951.1 WP_021369008.1 427 427 yes 1890154 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 548480 Bifidobacterium longum, Bifidobacterium longum subsp. infantis ATCC 55813 Bacteria UP000028505, UP000004443 494113286, 227212815 EEI80696.1 WP_007054064.1 fig|548480.3.peg.952 635 917 yes 1890155 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 105972 Methylosarcina fibrata Bacteria 522053484 WP_020564693.1 621 622 yes 1890156 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265425 Salinimonas chungwhensis Bacteria 517814059 WP_018984267.1 618 622 yes 1890157 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 335952, 1227457 Halococcus thailandensis, Halococcus thailandensis JCM 13552 Archaea 495017018, 445799279 EMA49660.1 WP_007743027.1 M0MZ21 M0MZ21_9EURY 449 481 yes 1890158 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1312922 Cupriavidus sp. WS Bacteria 519050064 WP_020205939.1 625 628 yes 1890159 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262884 Eubacterium sp. CAG:202 Environmental samples UP000017996 547825891, 524458584 WP_022234158.1 434 434 yes 1890160 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 367189, 797209 Haladaptatus paucihalophilus, Haladaptatus paucihalophilus DX253 Archaea 495254313, 320550814 EFW92464.1 WP_007979068.1 E7QSQ5 E7QSQ5_9EURY 457 479 yes 1890161 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1249483 Leptospira yanagawae serovar Saopaulo str. Sao Paulo Bacteria UP000013996 501478214 EOQ87693.1 506 511 yes 1890162 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40214, 575586 Acinetobacter johnsonii, Acinetobacter johnsonii SH046 Bacteria UP000053042, UP000012047 491543375, 262315199 EEY96239.1 WP_005400993.1 627 630 yes 1890163 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053233 Bacillus cereus, Bacillus cereus VD133 Bacteria UP000036076, UP000014018 507039307, 500311833 EOO32960.1 WP_016110978.1 fig|1053233.3.peg.3459 586 586 yes 1890164 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1482 Virgibacillus halodenitrificans Bacteria 635569884 593 594 yes 1890165 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1854, 981405, 1352929 Frankia sp. Allo2, Frankia sp. CcI6 Bacteria UP000028535, UP000019524 564016693, 667814995, 563313949 KFB03559.1, ETA02249.1 WP_023840840.1 622 657 yes 1890166 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 653685, 1423, 1034836, 1001582, 999891, 692420 Bacillus subtilis, Bacillus amyloliquefaciens XH7, Bacillus amyloliquefaciens LL3, Bacillus amyloliquefaciens TA208, Bacillus amyloliquefaciens DSM7 Bacteria UP000030083, UP000001437, UP000000308, UP000008307, UP000006562 503116897, 703580506, 341826736, 328910896, 328552499, 307605724 AIW32867.1, AEK87987.1, AEB62492.1, AEB22991.1 WP_013351590.1 fig|1001582.3.peg.938, fig|1034836.4.peg.809, fig|999891.3.peg.819, fig|692420.6.peg.1037 590 590 yes 1890167 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2238, 272569 Haloarcula marismortui, Haloarcula marismortui ATCC 43049 Archaea UP000001169 499542702, 55377988, 55230713, 68053064 AAV46132.1 WP_011223485.1, YP_135838.1 Q5V2X0 THIC_HALMA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 747719 fig|272569.1.peg.1107 454 480 yes 1890168 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262780 Clostridium sp. CAG:221 Environmental samples UP000018176 547754479, 524362274 WP_022167136.1 434 435 yes 1890169 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 90736 Moritella marina Bacteria 518272319 WP_019442527.1 640 668 yes 1890170 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1357295 Klebsiella pneumoniae, Klebsiella pneumoniae EGD-HP19 Bacteria UP000036212, UP000019480 544903140, 588304549 EXF38691.1 WP_021314092.1 626 631 yes 1890171 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263039 Bacteroides clarus CAG:160 Environmental samples UP000018226 547809916, 524436760 WP_022219145.1 560 561 yes 1890172 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1238, 1227812 Piscirickettsia salmonis, Piscirickettsia salmonis LF-89 = ATCC VR-1361 Bacteria UP000065118, UP000037680 701645248, 546140051 KGP97307.1, ERL61643.1 623 627 yes 1890173 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 879307, 1009464 Gardnerella vaginalis 315-A, Gardnerella vaginalis HMP9231 Bacteria UP000003666, UP000009050 333601923, 333393234 EGL13357.1, AEF31152.1 fig|1009464.3.peg.903, fig|879307.3.peg.1126 609 872 yes 1890174 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1123862 Klebsiella pneumoniae, Klebsiella pneumoniae subsp. pneumoniae Kp13 Bacteria UP000036212, UP000018866 644807304, 569555190 AHE46927.1 WP_025368557.1 626 631 yes 1890175 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 435 Acetobacter aceti Bacteria 498354771 WP_010668927.1 265 270 no 1890176 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380763 Paenibacillus sp. Br Bacteria UP000054119 738686540, 595754512, 595750178 EXX88693.1, EXX84791.1 WP_036586201.1 586 586 yes 1890177 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37487, 765910 Marichromatium purpuratum, Marichromatium purpuratum 984 Bacteria UP000005275 491366641, 570731487 AHF02650.1 WP_005224552.1 627 630 yes 1890178 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633, 396595 Thioalkalivibrio sp. K90mix Bacteria UP000009099 502746571, 288942957 ADC70656.1 WP_012981555.1 fig|396595.4.peg.139, fig|748652.3.peg.2238 627 629 yes 1890179 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298855 Novosphingobium sp. B-7 Bacteria 550927888 WP_022676350.1 616 621 yes 1890180 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168697 Salinispora arenicola Bacteria 517621704 WP_018791912.1 530 530 yes 1890181 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702, 1261058 Gardnerella vaginalis, Gardnerella vaginalis JCP7276 Bacteria UP000037770, UP000014591 523600193, 514596826 EPI57582.1 WP_020760233.1 609 872 yes 1890182 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 996, 1041826 Flavobacterium columnare, Flavobacterium columnare ATCC 49512 Bacteria UP000058566, UP000005638 503931879, 365737505 AEW86598.1 WP_014165873.1 604 604 yes 1890183 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 657323 Ruminococcus sp. SR1/5 Bacteria UP000007055 291547259 434 434 yes 1890184 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285, 563045 Comamonas testosteroni, Comamonas testosteroni S44 Bacteria UP000029609, UP000004078 489159703, 298718823 EFI59796.1 WP_003069354.1 625 647 yes 1890185 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2014, 446468 Nocardiopsis dassonvillei, Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 Bacteria UP000002219 502919732, 296847081 ADH69101.1 WP_013154708.1 fig|446468.4.peg.3896 552 564 yes 1890186 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1145178, 1095691, 1095692, 1095693, 1095697 Neisseria meningitidis, Neisseria meningitidis 98002, Neisseria meningitidis 97014, Neisseria meningitidis 2002038, Neisseria meningitidis 2006087, Neisseria meningitidis 97021 Bacteria UP000050419, UP000014593, UP000010735, UP000010727, UP000010760, UP000010745 488174524, 514068748, 432220029, 432219050, 432214118, 432207025 EPF53711.1, ELK75856.1, ELK74898.1, ELK70025.1, ELK63020.1 WP_002245732.1 fig|1145178.3.peg.2590, fig|1095697.3.peg.2633, fig|1095691.3.peg.2673, fig|1095693.3.peg.2649, fig|1095692.3.peg.2476 625 633 yes 1890187 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 652708, 575590 Bacteroidetes oral taxon 274, Bacteroidetes oral taxon 274 str. F0058 Bacteria UP000004685 496508823, 298275543 EFI17094.1 WP_009217106.1 583 583 yes 1890188 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1400860, 1400861 Candidatus Contendobacter odensis, Candidatus Contendobacter odensis Run_B_J11 Bacteria UP000019184 736407601, 577004566 WP_034430370.1 626 629 yes 1890189 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 378211, 1000565 Methyloversatilis universalis, Methyloversatilis universalis FAM5 Bacteria UP000005019 495336481, 333443798 EGK71759.1 WP_008061217.1 638 638 yes 1890190 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 691437 Geobacillus sp. C56-T3 Bacteria UP000000380 502909256, 297252033 ADI25479.1 WP_013144232.1 fig|691437.3.peg.431 562 562 yes 1890191 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 376219 Arthrospira sp. PCC 8005 Bacteria UP000032946 585308605, 375324655 459 461 yes 1890192 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 866771 Prevotella disiens FB035-09AN Bacteria UP000003610 302483413 EFL46419.1 533 533 yes 1890193 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151334 Clostridium difficile DA00165 Bacteria UP000015837 531384351 EQG76342.1 42 50 no 1890194 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1121961 Hirschia maritima Bacteria 517825554 WP_018995762.1 622 630 yes 1890195 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 765840, 1230338 Moraxella sp. CI24, Moraxella macacae 0408225 Bacteria UP000023795 497453007, 429541357 ELA09385.1 WP_009767205.1 fig|1230338.3.peg.706 635 638 yes 1890196 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 889239 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni LMG 23216 Bacteria UP000065538, UP000002976 488960148, 380599385 EIB19755.1 WP_002871180.1 fig|889239.3.peg.1004 430 430 yes 1890197 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2180, 523846 Methanothermus fervidus, Methanothermus fervidus DSM 2088 Archaea UP000002315 503178921, 311224448 ADP77304.1 WP_013413582.1 E3GYC2 E3GYC2_METFV 421 421 yes 1890198 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43657, 1268239 Pseudoalteromonas luteoviolacea, Pseudoalteromonas luteoviolacea B = ATCC 29581 Bacteria UP000031327, UP000011175 491635018, 441748449 WP_005492549.1 fig|1268239.3.peg.1600 645 650 yes 1890199 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 816, 997885, 665954, 556259, 702443, 469590 Bacteroides ovatus CL02T12C04, Bacteroides ovatus 3_8_47FAA, Bacteroides sp. D2, Bacteroides ovatus SD CMC 3f, Bacteroides sp. 2_2_4 Bacteria UP000003801, UP000003356, UP000003135, UP000005825, UP000003969 490431423, 392675122, 335934654, 313696729, 292631228, 229451397 EIY68564.1, EGM96637.1, EFS33564.1, EFF49862.1, EEO57188.1 WP_004303540.1 fig|556259.3.peg.4476, fig|702443.3.peg.5237, fig|469590.5.peg.3910, fig|665954.3.peg.1114, fig|997885.3.peg.334 565 565 yes 1890200 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56426, 696125 Bartonella clarridgeiae, Bartonella clarridgeiae 73 Bacteria UP000009101 503310092, 319402544 WP_013544753.1 fig|696125.3.peg.380 599 608 yes 1890201 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 240237 Woodsholea maritima Bacteria 518805087 WP_019961041.1 626 635 yes 1890202 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1280982 Escherichia coli, Escherichia coli HVH 31 (4-2602156) Bacteria UP000036210, UP000016309 545163584, 534655658 EQO11946.1 WP_021518346.1 626 631 yes 1890203 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33045, 634504 Bartonella grahamii, Bartonella grahamii as4aup Bacteria UP000001489 502296867, 240267302 ACS50890.1 WP_012754919.1 fig|634504.3.peg.599 602 611 yes 1890204 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644076 Silicibacter sp. TrichCH4B Bacteria UP000005082 496467627, 259347506 EEW59283.1 WP_009176472.1 fig|644076.3.peg.1150 596 604 yes 1890205 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1763, 1795, 700508 Mycobacterium neoaurum, Mycobacterium sp. VKM Ac-1815D Bacteria UP000033686, UP000018763 518343494, 772770814, 565684100 KJQ51735.1, AHC23960.1 WP_019513701.1 509 522 yes 1890206 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1773, 675522, 675521, 675512 Mycobacterium tuberculosis, Mycobacterium tuberculosis SUMu011, Mycobacterium tuberculosis SUMu010, Mycobacterium tuberculosis SUMu001 Bacteria UP000065426, UP000005934, UP000004824, UP000005346 490008359, 308363686, 308359745, 308216868 EFP52537.1, EFP48596.1, EFO76267.1 WP_003911173.1 544 547 yes 1890207 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 673860 Aciduliprofundum sp. MAR08-339 Archaea UP000010814 432134916 AGB04185.1 L0HJK0 L0HJK0_ACIS0 435 442 yes 1890208 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116082, 1116080, 1116087, 1116086, 1116085, 1116084, 1125645, 1116152, 1125644 Escherichia coli, Escherichia coli P0305260.8, Escherichia coli P0305260.6, Escherichia coli P0305260.13, Escherichia coli P0305260.12, Escherichia coli P0305260.11, Escherichia coli P0305260.10, Escherichia coli P0305260.2, Escherichia coli P0299438.2, Escherichia coli P0305260.1 Bacteria UP000036210, UP000012362, UP000012259, UP000012281, UP000012194, UP000012299, UP000012369, UP000012204, UP000012435, UP000012312 486201897, 729895616, 477353314, 477342328, 477315242, 477311389, 477309044, 477299976, 477124819, 476695336, 476684678 KHH88044.1, ENG22118.1, ENG11413.1, ENF85500.1, ENF81783.1, ENF79584.1, ENF70861.1, ENE04137.1, ENA00564.1, EMZ90092.1 WP_001550036.1 fig|1116082.3.peg.4349, fig|1125645.3.peg.4387, fig|1125644.3.peg.4149, fig|1116080.3.peg.4187, fig|1116087.3.peg.4265, fig|1116084.3.peg.4239, fig|1116152.3.peg.4160, fig|1116086.3.peg.4233, fig|1116085.3.peg.4273 626 631 yes 1890209 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 303, 1215087 Pseudomonas putida, Pseudomonas putida S12 Bacteria UP000054813, UP000017753 518267358, 734576806 AJA14020.1 WP_019437566.1 625 626 yes 1890210 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 768710 Desulfosporosinus youngiae DSM 17734 Bacteria UP000005104 374415362 EHQ87797.1 418 428 no 1890211 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 339862, 768710 Desulfosporosinus youngiae, Desulfosporosinus youngiae DSM 17734 Bacteria UP000005104 495054423, 374415363 EHQ87798.1 WP_007779259.1 422 432 yes 1890212 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1042877 Thermococcus sp. 4557 Archaea UP000000874 503777991, 340809146 AEK72303.1 WP_014011988.1 G0HLR2 G0HLR2_THES4 426 426 yes 1890213 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 698960 Gardnerella vaginalis 00703Dmash Bacteria UP000033074 388062766 EIK85371.1 fig|698960.3.peg.958 609 885 yes 1890214 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 108007, 926567 Thermanaerovibrio velox, Thermanaerovibrio velox DSM 12556 Bacteria UP000005730 493631169, 363983360 EHM09567.1 WP_006583061.1 418 429 yes 1890215 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 478749 Bryantella formatexigens DSM 14469 Bacteria UP000005561 255268627 EET61832.1 fig|478749.5.peg.895 434 435 yes 1890216 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34 Myxococcus xanthus Bacteria 521967248 WP_020478853.1 309 309 yes 1890217 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554 Pectobacterium carotovorum Bacteria UP000053038 497987596 WP_010301752.1 631 659 yes 1890218 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 50340 Pseudomonas fuscovaginae Bacteria UP000037883 516513604 WP_017902042.1 627 629 yes 1890219 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1311131 Acinetobacter baumannii 45057_4 Bacteria UP000023559 601347907 EYR98828.1 378 378 yes 1890220 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1311131 Acinetobacter baumannii 45057_4 Bacteria UP000023559 601347906 EYR98827.1 219 247 no 1890221 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1390, 1384051, 1091041 Bacillus amyloliquefaciens, Bacillus amyloliquefaciens UASWS BA1, Bacillus amyloliquefaciens IT-45 Bacteria UP000027101, UP000016639, UP000006456 505201415, 544265044, 449851571 ERK82683.1, AGF28563.1 WP_015388517.1 590 590 yes 1890222 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 13769, 547559 Natrialba magadii, Natrialba magadii ATCC 43099 Archaea UP000001879 490325733, 445576394 ELY30849.1 WP_004215204.1 L9V1A0 L9V1A0_NATMM 445 486 yes 1890223 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 58135, 760568 Desulfotomaculum kuznetsovii, Desulfotomaculum kuznetsovii DSM 6115 Bacteria UP000054111, UP000009229 503587348, 333821246 AEG13909.1 WP_013821424.1 fig|760568.4.peg.312 421 432 yes 1890224 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562729 Rheinheimera sp. E407-8 Bacteria UP000004374 383702690 fig|562729.3.peg.2744 587 591 yes 1890225 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 675815 Vibrio sp. RC586 Bacteria UP000006226 445993267, 262348890 EEY98029.1 WP_000071122.1 640 646 yes 1890226 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 482564, 179408 Oscillatoria nigroviridis, Oscillatoria sp. PCC 7112 Bacteria UP000010478 504989615, 428241653 AFZ07439.1 WP_015176717.1 fig|179408.3.peg.3738 455 457 yes 1890227 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1112216 Sphingomonas sp. PAMC 26617 Bacteria 497847469 WP_010161625.1 637 639 yes 1890228 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1438675, 1445862, 1328438, 1328436, 1328437, 1328439, 1328441, 1328440, 1328442, 1328443, 1328444, 1400156, 1400157, 1389420, 1389419, 1328445, 1433129 Escherichia coli, Escherichia coli BIDMC 71, Escherichia coli BIDMC 82, Escherichia coli BIDMC 6, Escherichia coli BIDMC 2B, Escherichia coli BIDMC 3, Escherichia coli BIDMC 9, Escherichia coli BIDMC 17A, Escherichia coli BIDMC 15, Escherichia coli BIDMC 17B, Escherichia coli BIDMC 19A, Escherichia coli BIDMC 19B, Escherichia coli BIDMC 43a, Escherichia coli BIDMC 43b, Escherichia coli LAU-EC9, Escherichia coli LAU-EC8, Escherichia coli BIDMC 19C, Escherichia coli IS5 Bacteria UP000036210, UP000027546, UP000024254, UP000021799, UP000019870, UP000022721, UP000021746, UP000020939, UP000019917, UP000022975, UP000021579, UP000020410, UP000021413, UP000020338, UP000018663, UP000018729, UP000017155, UP000018893 550713485, 723233348, 635821334, 612266883, 575663219, 575642257, 575629120, 575621783, 575619133, 575615405, 575615047, 575608653, 575598449, 575586885, 575577110, 564941842, 564907684, 550208556, 568392751 AIX65991.1, KDG02555.1, EZQ60426.1, ETY61697.1, ETY40970.1, ETY28000.1, ETY20756.1, ETY18167.1, ETY14449.1, ETY14115.1, ETY07777.1, ETX97658.1, ETX86225.1, ETX76569.1, ETE36472.1, ETE08033.1, ERO99018.1 WP_022646394.1 626 631 yes 1890229 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 102129 Leptolyngbya sp. PCC 7375 Bacteria UP000009889 493564320, 425762469 EKV03322.1 WP_006517690.1 fig|102129.3.peg.4786 453 455 yes 1890230 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116126, 1116033, 1116032 Escherichia coli, Escherichia coli 2846750, Escherichia coli 2872000, Escherichia coli 2871950 Bacteria UP000036210, UP000012305, UP000012326, UP000012275 487506032, 476654893, 476129425, 476129334 EMZ61060.1, EMV51662.1, EMV51576.1 WP_001705591.1 fig|1116126.3.peg.4382, fig|1116033.3.peg.4571, fig|1116032.3.peg.4491 626 631 yes 1890231 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2209, 1236903 Methanosarcina mazei, Methanosarcina mazei Tuc01 Archaea UP000034872, UP000011718 505223819, 452208803, 452098705 AGF95645.1 WP_015410921.1, YP_007488917.1 M1Q042 M1Q042_METMZ 398 398 no 1890232 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1332069 Pantoea sp. AS-PWVM4 Bacteria UP000016607 544759582, 544006623 ERK05465.1 WP_021186419.1 631 641 yes 1890233 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 155194, 1094492 Bartonella bovis, Bartonella bovis m02 Bacteria UP000014026 498388257, 478419719 ENN93395.1 WP_010702217.1 fig|1094492.3.peg.428 598 608 yes 1890234 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 119394, 688269 Thermotoga thermarum, Thermotoga thermarum DSM 5069 Bacteria UP000006804 503698575, 335365491 AEH51436.1 WP_013932651.1 fig|688269.3.peg.1413 438 438 yes 1890235 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28125, 1401072, 868129, 553171 Prevotella bivia, Prevotella bivia DNF00650, Prevotella bivia DSM 20514, Prevotella bivia JCVIHMP010 Bacteria UP000029607, UP000002786, UP000016040 490466486, 690787856, 388593481, 282588066 KGF34501.1, EIM33719.1, EFB93245.1 WP_004337024.1 523 523 yes 1890236 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262749 Bacteroides sp. CAG:714 Environmental samples UP000018068 547938517, 524614108 WP_022340007.1 565 565 yes 1890237 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35746, 1227459 Haloferax gibbonsii, Haloferax gibbonsii ATCC 33959 Archaea UP000066124 491117659, 445728425 ELZ80031.1 WP_004976114.1 M0H6A4 M0H6A4_9EURY 436 465 yes 1890238 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 671228, 879309 Veillonella sp. oral taxon 158, Veillonella sp. oral taxon 158 str. F0412 Bacteria UP000003565 496721980, 313441164 EFR59591.1 WP_009352399.1 434 434 yes 1890239 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55208, 561231 Pectobacterium wasabiae, Pectobacterium wasabiae WPP163 Bacteria UP000029436, UP000000315 502581639, 261603589 ACX86075.1 WP_012822040.1 fig|561231.5.peg.211 631 646 yes 1890240 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 693977 Deinococcus proteolyticus MRP Bacteria UP000007718 324316094 ADY27208.1 fig|693977.3.peg.2376 576 595 yes 1890241 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 379, 348824 Rhizobium sp. LPU83 Bacteria UP000019443 636778919, 584454763 WP_024315360.1 603 608 yes 1890242 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 595460 Rhodopirellula sp. SWK7 Bacteria UP000012028 496387315, 460847688 EMI45223.1 WP_009096305.1 fig|595460.3.peg.2430 439 441 yes 1890243 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 38303, 525264 Corynebacterium pseudogenitalium, Corynebacterium pseudogenitalium ATCC 33035 Bacteria UP000003020 491466683, 311303659 EFQ79738.1 WP_005324444.1 588 593 yes 1890244 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1549 Clostridium sporosphaeroides Bacteria 518916149 WP_020072024.1 436 437 yes 1890245 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1214121, 160492 Xylella fastidiosa 32, Xylella fastidiosa 9a5c Bacteria UP000018676, UP000000812 564938138, 9106981 ETE32841.1, AAF84694.1 Q9PC93 THIC_XYLFA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2137509 fig|160492.1.peg.1881 595 629 yes 1890246 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1120938 Actinomadura flavalba Bacteria 517485639 WP_018656216.1 574 578 yes 1890247 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281250, 1182690 Escherichia coli, Escherichia coli UMEA 3489-1, Escherichia coli KTE84 Bacteria UP000036210, UP000018732, UP000010685 486354724, 565521908, 431353271 ETF33743.1, ELG40025.1 WP_001591316.1 fig|1182690.3.peg.155 626 631 yes 1890248 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 355249 Streptomyces sp. Tu6071 Bacteria UP000003955 495099799, 332745619 EGJ76060.1 WP_007824622.1 598 600 yes 1890249 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 338188, 997888 Bacteroides finegoldii, Bacteroides thetaiotaomicron CL09T03C10 Bacteria UP000007995 495035465, 408473996 EKJ92518.1 WP_007760998.1 562 562 yes 1890250 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262778 Clostridium sp. CAG:169 Environmental samples UP000018302 547606153, 524303590 WP_022116818.1 435 435 yes 1890251 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1078083 Staphylococcus sp. HGB0015 Bacteria UP000014407 512476001, 512049395 EPD49039.1 WP_016426030.1 fig|1078083.3.peg.1794 578 578 yes 1890252 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37372, 1235804 Helicobacter bilis, Helicobacter bilis WiWa Bacteria UP000029870, UP000012527 490188964, 696180384, 696178385, 476631880 KGL23971.1, KGL22171.1, EMZ38411.1 WP_004087563.1 fig|1235804.3.peg.1581 452 453 yes 1890253 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 370405, 395494 Gallionella capsiferriformans, Gallionella capsiferriformans ES-2 Bacteria UP000001235 503059778, 302582841 ADL56852.1 WP_013294754.1 fig|395494.3.peg.678 623 623 yes 1890254 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1447529 Pseudomonas aeruginosa, Pseudomonas aeruginosa 3574 Bacteria UP000065817, UP000023845 685902757, 611863020 EZO39317.1 WP_031642968.1 627 627 yes 1890255 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2173 Methanobrevibacter smithii Archaea 518094332 WP_019264540.1 423 424 yes 1890256 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287233 Mesorhizobium sp. LNHC221B00 Bacteria UP000020036 563573165, 563155879 ESY79450.1 WP_023778384.1 596 611 yes 1890257 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1167634, 85698, 562971, 1216976 Achromobacter xylosoxidans NH44784-1996, Achromobacter xylosoxidans, Achromobacter xylosoxidans C54, Achromobacter xylosoxidans NBRC 15126 Bacteria UP000013965, UP000056101, UP000057095, UP000018702 528984359, 493434409, 846570733, 690304567, 566054479, 317401217, 777202327, 507100967 KMJ91024.1, AIR54103.1, AHC50152.1, EFV81861.1 YP_008029676.1, WP_006389952.1 636 637 yes 1890258 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 253107, 1227499 Natronolimnobius innermongolicus, Natronolimnobius innermongolicus JCM 12255 Archaea 494468350, 445607300 ELY61187.1 WP_007257850.1 L9XHV6 L9XHV6_9EURY 458 482 yes 1890259 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1335421 Mycobacterium intracellulare MIN_052511_1280 Bacteria UP000022140 576332103 ETZ26742.1 532 534 yes 1890260 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 665939 Campylobacter sp. 10_1_50 Bacteria UP000004588 496651653, 363651213 EHL90290.1 WP_009294474.1 fig|665939.3.peg.888 431 431 yes 1890261 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34067, 1198232, 522456 Cycloclasticus sp. 7-ME, Cycloclasticus sp. PY97M Bacteria UP000015380, UP000015462 511757060, 528327267, 511531968 AGS38530.1, EPD13254.1 WP_016390377.1 619 621 yes 1890262 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1280946 Hyphomonas sp. 25B14_1 Bacteria UP000027037 736794340, 630772517 KCZ54225.1 WP_034796543.1 567 567 no 1890263 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 649841, 1163617 sulfur-oxidizing bacterium NBRC 105220, Sulfuricella denitrificans skB26 Bacteria UP000015559 496498784, 540595559 WP_009207320.1 618 623 yes 1890264 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1126, 1160285 Microcystis aeruginosa, Microcystis aeruginosa PCC 9809 Bacteria UP000004775 490266169, 389828953 WP_004162805.1 fig|1160285.3.peg.4942 457 460 yes 1890265 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 880, 526222 Desulfovibrio salexigens, Desulfovibrio salexigens DSM 2638 Bacteria UP000002601 506332491, 242122698 ACS80394.1 WP_015852210.1 fig|526222.3.peg.2339 420 422 no 1890266 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40214, 1217663 Acinetobacter johnsonii, Acinetobacter johnsonii CIP 64.6 Bacteria UP000053042, UP000013109 490830720, 479890791 ENU40822.1 WP_004692806.1 fig|1217663.3.peg.400 627 630 yes 1890267 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 529 534 yes 1890268 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 741978 blood disease bacterium R229 Bacteria 344168474 629 631 yes 1890269 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84096, 1423140, 1027371 Gordonia alkanivorans, Gordonia alkanivorans CGMCC 6845, Gordonia alkanivorans NBRC 16433 Bacteria UP000035035, UP000003558 493400840, 563357518, 343765807 ETA06653.1 WP_006356939.1 551 563 yes 1890270 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913075 Salmonella enterica subsp. enterica serovar Inverness str. R8-3668 Bacteria UP000003532 353590358 EHC48901.1 fig|913075.3.peg.4602 181 198 no 1890271 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702, 525284, 585528 Gardnerella vaginalis, Gardnerella vaginalis ATCC 14019, Gardnerella vaginalis ATCC 14018 Bacteria UP000037770, UP000001453, UP000035707 503164877, 311114511, 310946005, 757812338 ADP38709.1 WP_013399538.1, YP_003985732.1 fig|525284.18.peg.624 609 881 yes 1890272 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3695 Populus trichocarpa x Populus deltoides Plants 118489266 ABK96438.1 553 637 yes 1890273 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1009418 Verrucomicrobia bacterium SCGC AAA164-M04 Bacteria 518994584 WP_020150459.1 675 699 yes 1890274 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1217675, 1173062 Acinetobacter schindleri NIPH 900, Acinetobacter sp. HA Bacteria UP000018438, UP000018434 490948282, 479967766, 388609226 ENV12235.1, EIM38418.1 WP_004810108.1 fig|1173062.3.peg.2399, fig|1217675.3.peg.2717 627 631 yes 1890275 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262876 Eggerthella sp. CAG:298 Environmental samples UP000018266 547962635, 524648087 WP_022362863.1 431 435 yes 1890276 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1517, 698948 Thermoanaerobacterium thermosaccharolyticum, Thermoanaerobacterium thermosaccharolyticum M0795 Bacteria UP000010845 505124180, 433292771 AGB18593.1 WP_015311282.1 fig|698948.3.peg.927 432 433 yes 1890277 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1182725 Escherichia coli, Escherichia coli KTE146 Bacteria UP000036210, UP000010643 486387883, 431410723 ELG93876.1 WP_001601079.1 fig|1182725.3.peg.20 626 631 yes 1890278 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1157637 Streptomyces sp. BoleA5 Bacteria 517384257 WP_018558190.1 579 581 yes 1890279 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36854, 756499 Desulfitobacterium dehalogenans, Desulfitobacterium dehalogenans ATCC 51507 Bacteria UP000006053 504606780, 390524664 AFM00395.1 WP_014793882.1 428 432 yes 1890280 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 574566 Coccomyxa sp. C-169 Plants UP000007264 545359944, 384247361 EIE20848.1 XP_005645392.1 546 560 yes 1890281 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 262668, 1217648 Acinetobacter beijerinckii, Acinetobacter beijerinckii CIP 110307 Bacteria UP000017670 491202616, 480067533 ENW06374.1 WP_005060958.1 fig|1217648.3.peg.2050 626 631 yes 1890282 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1288036 Mycobacterium marinum MB2 Bacteria UP000014976 521812284 EPQ71501.1 474 508 yes 1890283 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 516726685 WP_018068074.1 598 605 yes 1890284 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219, 74547 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9313 Bacteria UP000001423 499442074, 47606124, 33640546 WP_011129538.1 Q7V906 THIC_PROMM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 567252 fig|74547.1.peg.160 457 459 yes 1890285 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1321821 Porphyromonas gingivalis F0185 Bacteria UP000016634 543978438 ERJ82357.1 599 609 yes 1890286 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40373 Acinetobacter sp. CIP-A165 Bacteria UP000013225 490806114, 479881055 ENU31933.1 WP_004668237.1 fig|40373.3.peg.240 626 631 yes 1890287 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28173, 1051649, 1238446, 1238451, 1238449, 1238448, 1238441, 1238432, 1238445, 1238431, 1238430 Vibrio nigripulchritudo, Vibrio nigripulchritudo ATCC 27043, Vibrio nigripulchritudo SFn27, Vibrio nigripulchritudo Wn13, Vibrio nigripulchritudo SO65, Vibrio nigripulchritudo SFn135, Vibrio nigripulchritudo FTn2, Vibrio nigripulchritudo ENn2, Vibrio nigripulchritudo Pon4, Vibrio nigripulchritudo BLFn1, Vibrio nigripulchritudo AM115 Bacteria UP000033748, UP000004979, UP000018158, UP000018029, UP000018371, UP000018224, UP000018247, UP000017989, UP000018203, UP000018323, UP000018251 549691144, 490542545, 342819739, 549131451, 549032338, 549021931, 549013693, 548993880, 548991693, 548975772, 548972356, 548962891, 548952396 EGU54576.1 YP_008622876.1, WP_004407669.1 640 646 yes 1890288 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2162, 1204725 Methanobacterium formicicum, Methanobacterium formicicum DSM 3637 Archaea UP000062768, UP000007360 490129314, 407816572 EKF87134.1 WP_004029716.1 K2RFF9 K2RFF9_METFO 424 424 yes 1890289 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 654, 1073384, 998088 Aeromonas veronii, Aeromonas veronii AER397, Aeromonas veronii B565 Bacteria UP000051545, UP000005386, UP000000312 491490969, 404619658, 328806461 EKB16567.1, AEB51660.1 WP_005348704.1 fig|1073384.3.peg.96, fig|998088.4.peg.3663 645 663 yes 1890290 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65058, 1258583 Corynebacterium ulcerans, Corynebacterium ulcerans NCTC 12077 Bacteria UP000029905, UP000018265 560541661, 559270520 ESU57793.1 WP_023635915.1 558 569 yes 1890291 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 512649, 1219077 Vibrio azureus, Vibrio azureus NBRC 104587 Bacteria UP000016567 545474937, 543445080 WP_021711234.1 640 646 yes 1890292 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 563177, 933801 Acidianus hospitalis, Acidianus hospitalis W1 Archaea UP000008458 503541931, 332694624 AEE94091.1 WP_013776007.1 F4B3Q4 F4B3Q4_ACIHW 442 442 yes 1890293 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2248, 1227484 Halorubrum saccharovorum, Halorubrum saccharovorum DSM 1137 Archaea UP000053331 490145613, 445691072 ELZ43267.1 WP_004045944.1 M0E8M8 M0E8M8_9EURY 452 482 yes 1890294 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65058, 996634 Corynebacterium ulcerans, Corynebacterium ulcerans 0102 Bacteria UP000029905, UP000002821 504649442, 698189559, 393403252 AIT89434.1 WP_014836544.1 556 569 yes 1890295 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 338188, 483215 Bacteroides finegoldii, Bacteroides finegoldii DSM 17565 Bacteria UP000003768 495029502, 260621727 EEX44598.1 WP_007755058.1 562 562 yes 1890296 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 198431 uncultured prokaryote Environmental samples 374849798 444 447 yes 1890297 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76112, 1123367 Thauera linaloolentis, Thauera linaloolentis 47Lol = DSM 12138 Bacteria UP000013232 490461663, 479302463 ENO90563.1 WP_004332226.1 637 638 yes 1890298 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469614, 1262981 Erysipelotrichaceae bacterium 6_1_45, Erysipelotrichaceae bacterium CAG:64 Bacteria, Environmental samples UP000003818, UP000018179 496094342, 371657057, 524554119 EHO22367.1 WP_008818849.1 fig|469614.3.peg.3786 435 435 yes 1890299 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265734, 1265738 Rhodopirellula maiorica, Rhodopirellula maiorica SM1 Bacteria UP000011991 495974155, 460165809 EMI19388.1 WP_008698734.1 fig|1265738.3.peg.3681 441 442 yes 1890300 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151280 Clostridium difficile CD104 Bacteria UP000015902 531189508 EQE92123.1 205 215 no 1890301 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1085389, 1053178 Bacillus cereus, Bacillus cereus B5-2, Bacillus cereus BAG2O-3 Bacteria UP000036076, UP000014035, UP000014002 507006531, 500542791, 500398760 EOQ07324.1, EOP14670.1 WP_016085544.1 fig|1053178.3.peg.333, fig|1085389.3.peg.5725 586 586 yes 1890302 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151280 Clostridium difficile CD104 Bacteria UP000015902 531189527 EQE92142.1 222 222 no 1890303 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 263, 676032 Francisella tularensis, Francisella sp. 3523 Bacteria UP000029036, UP000008303 504361411, 332184266 AEE26520.1 WP_014548513.1 fig|676032.3.peg.1225 592 592 yes 1890304 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1267535 Acidobacteriaceae bacterium KBS 96 Bacteria 522212674 WP_020719793.1 457 462 yes 1890305 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1270 Micrococcus luteus Bacteria UP000032023 738364342, 612094752 EZP53193.1 WP_036316596.1 591 607 yes 1890306 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1409962, 1409963, 1409966, 1203546, 1203544 Klebsiella pneumoniae, Klebsiella pneumoniae MRSN 2404, Klebsiella pneumoniae MRSN 3562, Klebsiella pneumoniae MRSN HE12, Klebsiella pneumoniae subsp. pneumoniae WGLW3, Klebsiella pneumoniae subsp. pneumoniae WGLW1 Bacteria UP000036212, UP000034121, UP000033975, UP000034466, UP000005792, UP000005355 490281971, 839155915, 816118524, 816092110, 816071294, 405598901, 405589339 KMB35225.1, KKJ65584.1, KKJ39580.1, KKJ19031.1, EKB72089.1, EKB62907.1 WP_004177870.1 fig|1162297.3.peg.1196, fig|1203544.3.peg.4935 626 631 yes 1890307 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1773 Mycobacterium tuberculosis Bacteria UP000065426 515092225 WP_016721438.1 544 547 yes 1890308 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 330, 1149133 Pseudomonas pseudoalcaligenes, Pseudomonas pseudoalcaligenes KF707 Bacteria UP000033611, UP000011163 489548433, 442901024 ELS27023.1 WP_003453073.1 627 627 yes 1890309 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1267512 Klebsiella pneumoniae, Klebsiella pneumoniae subsp. pneumoniae B5055 Bacteria UP000036212, UP000014613 514078213, 513499823 EPF42638.1 WP_016530433.1 fig|1267512.3.peg.2678 602 604 yes 1890310 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68570, 1434306, 1395572, 1316445 Streptomyces albulus, Streptomyces albulus ZpM, Streptomyces albulus PD-1, Streptomyces albulus CCRC 11814 Bacteria UP000026918, UP000032720, UP000019597, UP000014149 514430979, 785759166, 636568065, 594647387, 508095475 AKA04954.1, AIA04750.1, EXU91490.1, EOT05556.1 WP_016570815.1 fig|1316445.3.peg.573 591 594 yes 1890311 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 1316587 Fusobacterium nucleatum, Fusobacterium nucleatum CTI-6 Bacteria UP000017154 552906428, 551182416 ERT46327.1 WP_023037928.1 433 433 yes 1890312 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1173957, 1238192, 1238202 Vibrio parahaemolyticus, Vibrio parahaemolyticus 98-513-F52, Vibrio parahaemolyticus VP2007-007, Vibrio parahaemolyticus 50 Bacteria UP000028114, UP000027788, UP000022971, UP000019048 659006126, 738584086, 655779470, 582060760, 573513809 KHQ87448.1, KEE61931.1, EVT77697.1, ETT13715.1 WP_029838768.1 640 646 yes 1890313 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42684, 1214242 Streptomyces collinus, Streptomyces collinus Tu 365 Bacteria UP000015423 529243689, 529198850 AGS70596.1 WP_020941058.1 592 594 yes 1890314 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 334771, 583356 Ignisphaera aggregans, Ignisphaera aggregans DSM 17230 Archaea UP000001304 503068784, 305663694, 304378263 ADM28102.1 WP_013303752.1, YP_003859982.1 E0SPP6 E0SPP6_IGNAA 422 422 yes 1890315 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1470593 Pseudomonas sp. RIT357 Bacteria UP000024021 696315012, 612105620 EZP63918.1 WP_032890434.1 627 629 yes 1890316 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262878 Eubacterium sp. CAG:115 Environmental samples UP000018005 547217059, 524094867 WP_021957341.1 437 437 yes 1890317 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 211586, 70863 Shewanella oneidensis MR-1, Shewanella oneidensis Bacteria UP000008186 UP000008186 24373992, 499384930, 24348446, 29337050 AAN55479.1 NP_718035.1, WP_011072421.1 Q8EED7 THIC_SHEON Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 201589 fig|211586.1.peg.2216 678 721 yes 1890318 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 723171 Vibrio sp. F10 Bacteria 515605607 WP_017038207.1 640 649 yes 1890319 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 196015 Caldimonas manganoxidans Bacteria 518390523 WP_019560730.1 622 626 yes 1890320 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553088 Chitiniphilus shinanonensis Bacteria 517576291 WP_018746499.1 636 637 yes 1890321 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 423351, 714943 Mucilaginibacter paludis, Mucilaginibacter paludis DSM 18603 Bacteria UP000002774 495788493, 373895070 EHQ30967.1 WP_008513072.1 627 627 yes 1890322 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 1339279, 1339282 Bacteroides fragilis, Bacteroides fragilis str. 20793-3, Bacteroides fragilis str. 2-F-2 #7 Bacteria UP000036847, UP000021122, UP000023248 695494668, 596189779, 595901158 EYA38664.1, EXY21760.1 WP_032579957.1 564 564 yes 1890323 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 343, 487909, 1205753 Xanthomonas translucens, Xanthomonas translucens pv. undulosa, Xanthomonas translucens DAR61454 Bacteria UP000055854, UP000035194, UP000011213 489562789, 828454342, 440377148 AKK68741.1, ELQ13800.1 WP_003467316.1 fig|1205753.3.peg.1114 620 625 yes 1890324 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 357276, 997877 Bacteroides dorei, Bacteroides dorei CL03T12C01 Bacteria UP000028592, UP000004019 671711312, 392647971 AII63585.1, EIY41661.1 fig|997877.3.peg.27 565 565 yes 1890325 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1049970 Leptospira kmetyi serovar Malaysia str. Bejo-Iso9 Bacteria UP000018730 529320547 EQA52690.1 522 522 yes 1890326 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 219748 Clostridium tunisiense Bacteria 515984306 WP_017414889.1 437 437 yes 1890327 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285450, 1352936 Streptomyces roseochromogenus, Streptomyces roseochromogenes subsp. oscitans DS 12.976 Bacteria UP000017984 559008736, 558537366 EST28635.1 WP_023548682.1 592 594 yes 1890328 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151308 Clostridium difficile 655 Bacteria UP000015794 531293368 EQF89112.1 137 137 no 1890329 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 3880 Medicago truncatula Plants UP000002051 388517931 AFK47027.1 200 212 no 1890330 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262758 Blautia sp. CAG:52 Environmental samples UP000018177 547758408, 524366785 WP_022170808.1 435 436 yes 1890331 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 57676 Rhizobium mongolense Bacteria 550969306 WP_022717601.1 600 608 yes 1890332 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 116 117 no 1890333 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 101192, 867904 Methanomethylovorans hollandica, Methanomethylovorans hollandica DSM 15978 Archaea UP000010866 505136437, 435850314, 433660944 AGB48370.1 WP_015323539.1, YP_007311900.1 L0KUL6 L0KUL6_METHD 429 429 yes 1890334 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717, 1450520, 1206106, 698963 Corynebacterium diphtheriae, Corynebacterium diphtheriae bv. mitis str. ISS 3319, Corynebacterium diphtheriae DSM 43988, Corynebacterium diphtheriae C7 (beta) Bacteria UP000033584, UP000035512, UP000016295, UP000007160 504084433, 827486470, 535931081, 372102631, 777191047 KLN41455.1, ERA61009.1, AEX66228.1 WP_014318427.1 fig|698963.3.peg.31 592 599 yes 1890335 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 262489 delta proteobacterium MLMS-1 Bacteria UP000005853 494504267, 93453136 EAT03607.1 WP_007293728.1 fig|262489.4.peg.3138 428 428 yes 1890336 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406 Paenibacillus polymyxa Bacteria UP000031922 515234288 WP_016819331.1 591 614 yes 1890337 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197222, 1128912 Glaciecola mesophila, Glaciecola mesophila KMM 241 Bacteria UP000006263 494050467, 410153543 WP_006992578.1 fig|1128912.3.peg.2111 620 628 yes 1890338 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158184 Thioalkalivibrio sp. ALM2T Bacteria 518424380 WP_019594587.1 627 629 yes 1890339 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1150591 Mycobacterium xenopi RIVM700367 Bacteria UP000003584 383331057 EID09576.1 fig|1150591.3.peg.4094 546 549 yes 1890340 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 471871 Clostridium sporogenes ATCC 15579 Bacteria UP000006610 187772130 EDU35932.1 444 444 yes 1890341 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316 Pseudomonas stutzeri Bacteria UP000037382 740871173, 627772095 AHY41318.1 WP_038656421.1 626 626 yes 1890342 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262962 Ruminococcus sp. CAG:57 Environmental samples UP000018131 547882030, 524531232 WP_022287424.1 256 256 no 1890343 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 471 Acinetobacter calcoaceticus Bacteria UP000032475 516051335 WP_017481918.1 621 625 yes 1890344 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314263, 89187 Roseovarius nubinhibens, Roseovarius nubinhibens ISM Bacteria UP000005954 497499936, 83836273 EAP75571.1 WP_009814134.1 fig|89187.3.peg.2294 594 606 yes 1890345 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 497321 Thauera sp. 63 Bacteria UP000013007 490421241, 479286404 ENO74504.1 WP_004293502.1 638 638 yes 1890346 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 93369 Pseudaminobacter salicylatoxidans Bacteria 518001735 WP_019171943.1 606 610 yes 1890347 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1162282 Rhodanobacter sp. 115 Bacteria UP000004557 495485419, 388441212 EIL97508.1 WP_008210105.1 fig|1162282.3.peg.961 624 625 yes 1890348 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 515264, 857293 Caloramator australicus, Caloramator australicus RC3 Bacteria UP000007652 496184216, 397161675 WP_008908723.1 fig|857293.11.peg.1368 415 415 yes 1890349 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262836 Clostridium sp. CAG:75 Environmental samples UP000018032 547293125, 524182611 WP_022025846.1 320 340 no 1890350 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 328812, 999418 Parabacteroides goldsteinii, Parabacteroides goldsteinii CL02T12C30 Bacteria UP000036166, UP000006330 494930701, 409217970 EKN10943.1 WP_007656735.1 fig|999418.3.peg.3821 567 567 yes 1890351 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61624, 997761 Bacillus mucilaginosus, Paenibacillus mucilaginosus K02 Bacteria UP000007392 504462086, 384088091 AFH59527.1 WP_014649188.1 fig|997761.3.peg.425 597 607 yes 1890352 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 125587470 EAZ28134.1 558 588 yes 1890353 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1218598 Leptospira weilii serovar Ranarum str. ICFT Bacteria UP000012313 476506504 EMY78672.1 443 516 yes 1890354 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 945689 Xylella fastidiosa EB92.1 Bacteria UP000004011 338178897 EGO81875.1 fig|405441.5.peg.1198, fig|183190.5.peg.1174, fig|945689.3.peg.1607 561 563 yes 1890355 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 301375, 1110509 Methanosaeta harundinacea, Methanosaeta harundinacea 6Ac Archaea UP000053961, UP000005877 504398657, 357208951 AET63571.1 WP_014585759.1 G7WL17 G7WL17_METH6 433 433 yes 1890356 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537010 Desulfitobacterium hafniense DP7 Bacteria UP000004416 361852131 EHL04401.1 fig|537010.4.peg.4574 431 435 yes 1890357 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2180, 523846 Methanothermus fervidus, Methanothermus fervidus DSM 2088 Archaea UP000002315 503178608, 311224135 ADP76991.1 WP_013413269.1 E3GXF9 E3GXF9_METFV 425 425 yes 1890358 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 701175, 796620 Vibrio sp. N384, Vibrio sp. SP2010 Bacteria UP000030421, UP000002943 497286529, 309369729 EFP97242.1 WP_009600746.1 fig|796620.3.peg.1442 640 645 yes 1890359 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294, 1284404 Pseudomonas fluorescens, Pseudomonas fluorescens FH5 Bacteria UP000060991, UP000018841 696328731, 567817256 ETK38665.1 WP_032904056.1 627 629 yes 1890360 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33057, 303682, 305700 Thauera sp. 28, Thauera sp. 27 Bacteria UP000013096, UP000013140 489015332, 479305813, 479294550 ENO93913.1, ENO82650.1 WP_002925854.1 638 638 yes 1890361 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56957, 751945 Thermus oshimai, Thermus oshimai JL-2 Bacteria UP000000211 504878177, 410698215 AFV77282.1 WP_015065279.1 fig|751945.3.peg.2234, fig|1123390.3.peg.1522 432 435 yes 1890362 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 280239 Nocardiopsis chromatogenes Bacteria 516223002 WP_017626965.1 550 552 yes 1890363 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151334 Clostridium difficile DA00165 Bacteria UP000015837 531384627 EQG76618.1 67 70 no 1890364 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1400171 Klebsiella pneumoniae, Klebsiella pneumoniae UCI 18 Bacteria UP000036212, UP000023387 695818371, 839673830, 583505412 KMH47902.1, EWD69106.1 WP_032732188.1 626 631 yes 1890365 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116088 Escherichia coli, Escherichia coli P0305260.15 Bacteria UP000036210, UP000012350 487370187, 477325058 ENF94872.1 WP_001644095.1 fig|1116088.3.peg.3537 626 631 yes 1890366 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47877, 629267 Pseudomonas amygdali, Pseudomonas syringae pv. lachrymans str. M302278PT Bacteria UP000050412, UP000005479 492150080, 331014577 EGH94633.1 WP_005762982.1 628 629 yes 1890367 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43948, 595494 Tolumonas auensis, Tolumonas auensis DSM 9187 Bacteria UP000009073 502192362, 237500107 ACQ92700.1 WP_012729299.1 fig|595494.3.peg.1068 611 615 yes 1890368 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 102134, 767817 Desulfotomaculum gibsoniae, Desulfotomaculum gibsoniae DSM 7213 Bacteria UP000013520 493567769, 488454523 AGL00417.1 WP_006521071.1 432 432 yes 1890369 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1703 Brevibacterium linens Bacteria UP000031488 497570427 WP_009884611.1 590 612 yes 1890370 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158459, 1235834 Enterobacter sp. SP1, Enterobacter cloacae subsp. dissolvens SP1 Bacteria UP000019435 516029433, 586612286 AHJ75732.1 WP_017460016.1 626 630 yes 1890371 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151334 Clostridium difficile DA00165 Bacteria UP000015837 531383766 EQG75757.1 61 61 no 1890372 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384, 1033991 Rhizobium leguminosarum, Rhizobium leguminosarum bv. trifolii CB782 Bacteria UP000019085 645046839, 574593588 AHG48746.1 WP_025418141.1 602 608 yes 1890373 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 391904, 1682 Bifidobacterium longum, Bifidobacterium longum subsp. infantis ATCC 15697, Bifidobacterium longum subsp. infantis Bacteria UP000028505, UP000007256, UP000039602 501572767, 213523152, 735212830, 735210119, 735207453, 735204795, 735202145, 735199505, 735196838, 735194164, 320457781 ACJ51899.1 WP_012577180.1 fig|391904.3.peg.796 635 917 yes 1890374 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 163908 Anabaena sp. PCC 7108 Bacteria 515516437 WP_016949691.1 455 457 yes 1890375 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 395923, 685782 Bartonella rochalimae, Bartonella rochalimae ATCC BAA-1498 Bacteria UP000027336 737011310, 654324504, 319403905 KEC54201.1 WP_035007053.1 600 608 yes 1890376 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34073, 543728 Variovorax paradoxus, Variovorax paradoxus S110 Bacteria UP000050323, UP000000453 506347770, 239804266, 259518390 ACS21333.1 WP_015867489.1 C5CM74 THIC_VARPS Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7559822 fig|543728.3.peg.4723, fig|1150395.3.peg.590 624 628 yes 1890377 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 396323, 1341683, 1217652 Acinetobacter brisoui, Acinetobacter brisouii CIP 110357, Acinetobacter brisouii ANC 4119 Bacteria UP000053639, UP000018418, UP000018421 491040866, 554745361, 480005167 ESK50408.1, ENV47106.1 WP_004902535.1 fig|1217652.3.peg.1898 626 631 yes 1890378 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358 Agrobacterium tumefaciens Bacteria UP000064781 737225798, 618824832 KAJ33838.1 WP_035210238.1 599 607 yes 1890379 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 545276 Thioalkalivibrio sp. ALJ24 Bacteria 517766264 WP_018936472.1 627 629 yes 1890380 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217699 Acinetobacter sp. CIP 110321 Bacteria UP000016203 507094441, 505759095 EOR03195.1 WP_016165124.1 626 631 yes 1890381 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444165, 1444082, 1444268, 1444169, 1444140, 1444118, 1444216 Escherichia coli, Escherichia coli 3-020-07_S3_C2, Escherichia coli 3-020-07_S1_C2, Escherichia coli 2-474-04_S4_C3, Escherichia coli 3-373-03_S3_C2, Escherichia coli 3-267-03_S3_C1, Escherichia coli 2-011-08_S3_C1, Escherichia coli 1-176-05_S4_C1 Bacteria UP000036210, UP000027775, UP000028092, UP000028052, UP000028138, UP000028047, UP000027709, UP000024151 692998651, 658724540, 652213730, 652206837, 650086044, 650035104, 649969543, 611063015 KEJ65910.1, KDZ21554.1, KDZ15088.1, KDU07776.1, KDT58277.1, KDS95412.1, EZJ65700.1 WP_032185345.1 626 631 yes 1890382 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1049910 Leptospira interrogans serovar Icterohaemorrhagiae str. Verdun HP Bacteria UP000012092 464317622 EMO05114.1 272 282 no 1890383 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1423 Bacillus subtilis Bacteria UP000030083 518685306 WP_019846999.1 509 509 no 1890384 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1339284 Bacteroides fragilis str. 3397 T10 Bacteria UP000022725 595912744 EXY29776.1 260 260 no 1890385 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 446471 Xylanimonas cellulosilytica DSM 15894 Bacteria UP000002255 269304935 ACZ30485.1 fig|446471.6.peg.1492 579 587 yes 1890386 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204799, 1189611 Nitratireductor aquibiodomus, Nitratireductor aquibiodomus RA22 Bacteria UP000004622 494065157, 389665961 EIM77420.1 WP_007007228.1 fig|1189611.3.peg.631 597 604 yes 1890387 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 435998 Serratia marcescens, Serratia sp. WW4 Bacteria UP000055021, UP000011252 505189224, 445210427 AGE16097.1 WP_015376326.1 fig|435998.3.peg.291 632 647 yes 1890388 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 75612, 1419583 Pseudomonas mandelii, Pseudomonas mandelii PD30 Bacteria UP000026739 696520188, 633680411 KDD69966.1 WP_033055492.1 627 629 yes 1890389 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36870 Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis Bacteria UP000000562 30173415, 25166463 Q8D247 THIC_WIGBR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1734411 fig|36870.1.peg.505 603 604 yes 1890390 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 90371, 59201, 1124919 Salmonella enterica, Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar Agona str. 632182-2 Bacteria UP000054489, UP000028938, UP000033855, UP000017440 516011646, 818426445, 758751552, 758751518, 554361472 AKG32777.1, KIV48843.1, KIV48810.1, ESH98586.1 WP_017442229.1 626 631 yes 1890391 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59538 Pantholops hodgsonii Mammals 556746646 XP_005968787.1 612 612 yes 1890392 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1432555 Escherichia coli ISC7 Bacteria UP000019199 571180713 588 590 yes 1890393 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68213, 996637 Streptomyces griseoaurantiacus, Streptomyces griseoaurantiacus M045 Bacteria UP000003022 493110369, 329302179 EGG46071.1 WP_006141343.1 592 614 yes 1890394 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 497978, 980514, 1401639 Acinetobacter baumannii MDR-ZJ06, Acinetobacter baumannii TCDC-AB0715, Acinetobacter baumannii NCGM 237 Bacteria UP000009290, UP000006390, UP000016884 347592040, 323516360, 546203860 AEP04761.1, ADX90741.1 fig|992404.3.peg.3274, fig|1168590.3.peg.3325, fig|903896.3.peg.1493, fig|557600.3.peg.3160, fig|1221287.3.peg.1517, fig|1094474.3.peg.2883, fig|1094488.3.peg.664, fig|903917.3.peg.3835, fig|1221254.3.peg.3717, fig|903933.3.peg.3317, fig|886886.3.peg.2810, fig|981329.3.peg.1989, fig|1222033.3.peg.1220, fig|903895.3.peg.3590, fig|1217628.3.peg.3227, fig|1221256.3.peg.1087, fig|1221268.3.peg.3081, fig|525243.3.peg.879, fig|1217644.3.peg.3329, fig|1217636.3.peg.277, fig|1217673.3.peg.166, fig|903937.3.peg.837, fig|1221248.3.peg.236, fig|1221288.3.peg.3507, fig|1221271.3.peg.2874, fig|945556.3.peg.419, fig|1222031.3.peg.2179, fig|903914.3.peg.2311, fig|903920.3.peg.3367, fig|1221250.3.peg.81, fig|903925.3.peg.51, fig|1168588.3.peg.3611, fig|1094484.3.peg.838, fig|1216295.3.peg.292, fig|1116236.3.peg.1451, fig|903898.3.peg.580, fig|1221276.3.peg.211, fig|710094.4.peg.1881, fig|525242.3.peg.631, fig|1293574.3.peg.3060, fig|1198108.3.peg.2353, fig|1094479.3.peg.1163, fig|1224747.3.peg.3082, fig|1094480.3.peg.1718, fig|903901.3.peg.3745, fig|903894.3.peg.3009, fig|1094478.3.peg.1319, fig|903904.3.peg.3094, fig|1217646.3.peg.3355, fig|1221246.3.peg.2209, fig|1221277.3.peg.1668, fig|1210907.3.peg.2670, fig|1221266.3.peg.3470, fig|1221275.3.peg.1567, fig|1217630.3.peg.3465, fig|1221259.3.peg.486, fig|696749.3.peg.304, fig|1094477.3.peg.1723, fig|1217641.3.peg.794, fig|557601.3.peg.1361, fig|1217627.3.peg.3405, fig|1279013.3.peg.450, fig|1217640.3.peg.3399, fig|1221292.3.peg.4, fig|992403.3.peg.3051, fig|1221272.3.peg.2528, fig|1217985.3.peg.444, fig|903923.3.peg.2171, fig|400667.4.peg.265, fig|575584.3.peg.1939, fig|1217631.3.peg.3455, fig|903907.3.peg.326, fig|1116234.3.peg.985, fig|903912.3.peg.23, fig|405416.6.peg.373, fig|1221262.3.peg.346, fig|1221249.3.peg.498, fig|1221253.3.peg.23, fig|480119.5.peg.338, fig|1217642.3.peg.2669, fig|1278070.3.peg.520, fig|1221273.3.peg.1110, fig|903911.3.peg.1856, fig|592014.3.peg.1845, fig|1094475.3.peg.133, fig|509173.8.peg.3374, fig|886889.3.peg.430, fig|1217645.3.peg.273, fig|903926.3.peg.101, fig|1217635.3.peg.3443, fig|1217632.3.peg.3326, fig|903934.3.peg.34, fig|1221265.3.peg.2338, fig|1100841.3.peg.528, fig|981224.3.peg.23, fig|903903.3.peg.1192, fig|903924.3.peg.661, fig|903909.3.peg.2080, fig|903889.3.peg.2969, fig|945555.3.peg.3316, fig|889738.3.peg.3693, fig|903899.3.peg.3185, fig|1223564.3.peg.398, fig|1094481.3.peg.1061, fig|903892.3.peg.3047, fig|1094487.3.peg.888, fig|1217638.3.peg.286, fig|1221286.3.peg.3565, fig|981328.3.peg.350, fig|1116233.3.peg.1325, fig|1221290.3.peg.2383, fig|1221245.3.peg.3512, fig|497978.4.peg.304, fig|886888.3.peg.2978, fig|903931.3.peg.1889, fig|1217647.3.peg.2843, fig|1094486.3.peg.1107, fig|1217643.3.peg.3356, fig|903927.3.peg.26, fig|903906.3.peg.1533, fig|1224141.3.peg.326, fig|903935.3.peg.3702, fig|1224166.3.peg.516, fig|1221264.3.peg.3640, fig|1221251.3.peg.618, fig|1222032.3.peg.1613, fig|903908.3.peg.2661, fig|903932.3.peg.542, fig|1094471.3.peg.58, fig|1217637.3.peg.3302, fig|1221267.3.peg.2100, fig|1221270.3.peg.1485, fig|1094483.3.peg.1819, fig|903905.3.peg.79, fig|1094470.3.peg.2681, fig|980514.3.peg.314, fig|903919.3.peg.2436 621 626 yes 1890395 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570, 573, 1409961, 1438797, 1438727, 1400164, 1400176, 1328394, 1328425, 1284797, 1193292, 749535, 484021 Klebsiella pneumoniae, Klebsiella pneumoniae MRSN 1319, Klebsiella pneumoniae MGH-74, Klebsiella pneumoniae CHS 21, Klebsiella pneumoniae BIDMC 46b, Klebsiella pneumoniae UCI 25, Klebsiella pneumoniae UCICRE 8, Klebsiella pneumoniae BIDMC 36, Klebsiella pneumoniae DMC0799, Klebsiella pneumoniae subsp. pneumoniae 1084, Klebsiella sp. MS 92-3, Klebsiella pneumoniae NTUH-K2044 Bacteria UP000036212, UP000031269, UP000027549, UP000024851, UP000023295, UP000020590, UP000017456, UP000017262, UP000014848, UP000009209, UP000004004, UP000010106 497140519, 839788361, 839732687, 839721605, 839715994, 839700617, 839659309, 839652852, 839619190, 839294976, 749019955, 721488460, 712677887, 636405446, 612298765, 583548051, 583489259, 555048643, 554988282, 519465335, 402543854, 328536421, 238544785 KMI61100.1, KMI05936.1, KMH94974.1, KMH89425.1, KMH74247.1, KMH33679.1, KMH27306.1, KMG94010.1, KMD72919.1, KII01149.1, KGY32021.1, KGT65061.1, KDL82517.1, EZQ91620.1, EWE11436.1, EWD53095.1, ESL92918.1, ESL32871.1, EPO16329.1, AFQ68003.1, EGF62774.1 WP_009485012.1 fig|484021.4.peg.209, fig|749535.4.peg.2376, fig|1193292.6.peg.4795 626 631 yes 1890396 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1465, 1042163 Brevibacillus laterosporus, Brevibacillus laterosporus LMG 15441 Bacteria UP000005850 489430316, 666897539 AIG27216.1 WP_003335912.1 591 592 yes 1890397 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144670 Acinetobacter sp. CIP 51.11 Bacteria UP000018464 491390539, 480176487 ENX12949.1 WP_005248412.1 fig|1144670.3.peg.2754 627 631 yes 1890398 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1130300 crenarchaeote SCGC AAA261-F05 Archaea 516668993 WP_018032677.1 138 144 no 1890399 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 62319, 1227455 Halococcus saccharolyticus, Halococcus saccharolyticus DSM 5350 Archaea 492980261, 445795582 EMA46106.1 WP_006076928.1 M0MKC8 M0MKC8_9EURY 431 464 yes 1890400 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1192560, 1314885, 1194157, 1271863 Salmonella enterica, Salmonella enterica subsp. enterica serovar Cubana str. 76814, Salmonella enterica subsp. enterica serovar Cubana str. CVM42234, Salmonella enterica subsp. enterica serovar Cubana str. CFSAN001083, Salmonella enterica subsp. enterica serovar Cubana str. CFSAN002050 Bacteria UP000054489, UP000018534, UP000018510, UP000017373, UP000014943 526017495, 564143348, 560203646, 554414320, 523816300 ETA88728.1, ESV49946.1, ESJ42176.1, AGQ71581.1 WP_020838420.1 626 631 yes 1890401 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310778, 1310781, 1310770 Acinetobacter baumannii, Acinetobacter baumannii 426863, Acinetobacter baumannii 277047, Acinetobacter baumannii 1295549 Bacteria UP000028632, UP000022043, UP000021640, UP000021356 691045212, 593655734, 593608138, 593534129 EXS35556.1, EXR89808.1, EXR18585.1 WP_031994478.1 621 625 yes 1890402 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 246167 Vibrio crassostreae Bacteria UP000049932 515628713 WP_017061313.1 640 649 yes 1890403 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262938 Prevotella sp. CAG:924 Environmental samples UP000018357 546815310, 524019663 WP_021895452.1 524 524 yes 1890404 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 129337, 1482739, 1408282, 1095383, 1111068, 1406857, 1337888, 235909 Geobacillus sp. CAMR5420, Geobacillus sp. MAS1, Geobacillus sp. A8, Geobacillus thermoleovorans CCB_US3_UF5, Geobacillus thermoleovorans B23, Geobacillus kaustophilus GBlys, Geobacillus kaustophilus HTA426 Bacteria UP000027227, UP000018339, UP000015753, UP000005636, UP000029900, UP000016424, UP000001172 499549091, 635255054, 559464103, 530700990, 359286112, 618752257, 514404375, 81558096, 56378747 KDE50213.1, ESU72635.1, EQB95371.1, AEV17796.1 WP_011229874.1 Q5L325 THIC_GEOKA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 852196, 7568415 fig|1111068.3.peg.449, fig|235909.3.peg.1861 562 562 yes 1890405 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2061, 521096 Tsukamurella paurometabola, Tsukamurella paurometabola DSM 20162 Bacteria UP000001213 502893335, 296029545 ADG80315.1 WP_013128311.1 fig|521096.4.peg.4111 559 566 yes 1890406 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33029, 879306 Anaerococcus hydrogenalis, Anaerococcus hydrogenalis ACS-025-V-Sch4 Bacteria UP000005277 490954608, 325481272 EGC84313.1 WP_004816423.1 431 431 yes 1890407 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 504937, 1227488 Haloterrigena salina, Haloterrigena salina JCM 13891 Archaea 496172070, 445660304 ELZ13100.1 WP_008896577.1 M0BQB5 M0BQB5_9EURY 459 480 yes 1890408 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 291112 Photorhabdus asymbiotica Bacteria 502384269, 253779326 WP_012776585.1 fig|171440.1.peg.543, fig|291112.3.peg.464 619 645 yes 1890409 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1194405 Pseudomonas syringae pv. actinidiae ICMP 19096 Bacteria UP000018849 519276954 EPN47507.1 87 97 no 1890410 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 833, 59374 Fibrobacter succinogenes, Fibrobacter succinogenes subsp. succinogenes S85 Bacteria UP000001497 502575030, 302328123, 261371297 ADL27324.1, ACX74042.1 WP_012820272.1 fig|59374.5.peg.420 534 538 yes 1890411 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1194405 Pseudomonas syringae pv. actinidiae ICMP 19096 Bacteria UP000018849 519276959 EPN47510.1 369 369 yes 1890412 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1157634 Streptomyces sp. Amel2xE9 Bacteria 518825394 WP_019981348.1 600 607 yes 1890413 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 359407 519011411 WP_020167286.1 624 631 yes 1890414 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 195, 887313, 887281, 887314 Campylobacter coli, Campylobacter coli Z156, Campylobacter coli 7--1, Campylobacter coli Z163 Bacteria UP000062643, UP000003616, UP000004031, UP000004772 488873763, 380595497, 380547334, 380516320 EIB16227.1, EIA71256.1, EIA42453.1 WP_002785988.1 fig|887281.3.peg.981, fig|887314.3.peg.806, fig|887313.3.peg.866 429 430 yes 1890415 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 77133 uncultured bacterium Environmental samples UP000041370 407009664 EKE24751.1 627 631 yes 1890416 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 102134, 767817 Desulfotomaculum gibsoniae, Desulfotomaculum gibsoniae DSM 7213 Bacteria UP000013520 493567989, 488454725 AGL00619.1 WP_006521285.1 422 432 yes 1890417 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 187878, 593117 Thermococcus gammatolerans, Thermococcus gammatolerans EJ3 Archaea UP000001488 506339164, 240103326, 239910880, 259518383 ACS33771.1 WP_015858883.1, YP_002959635.1 C5A6A9 THIC_THEGJ Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7693147 426 426 yes 1890418 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 190898, 1286635 Desulfotignum phosphitoxidans, Desulfotignum phosphitoxidans DSM 13687 Bacteria UP000014216 494026333, 474485825 EMS77457.1 WP_006968532.1 fig|1286635.3.peg.4567 438 439 yes 1890419 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1465823 Herbaspirillum massiliense Bacteria 517969333 WP_019139541.1 636 637 yes 1890420 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1096546 Methylobacterium sp. GXF4 Bacteria UP000004753 494835240, 392728152 EIZ85461.1 WP_007561340.1 fig|1096546.3.peg.1794 622 628 yes 1890421 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1055192 Comamonas sp. B-9(2011) Bacteria 543580236 WP_021028579.1 625 644 yes 1890422 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317936 Nostoc sp. PCC 7107 Bacteria UP000010381 504925102, 427359254 AFY41976.1 WP_015112204.1 fig|317936.3.peg.1429 456 457 yes 1890423 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1085541, 1218577, 1218579 Leptospira interrogans serovar Australis str. 200703203, Leptospira interrogans str. 2002000631, Leptospira interrogans str. 2003000735 Bacteria UP000012220, UP000011940, UP000011982 476394542, 463312139, 463297951 EMY24053.1, EMJ78928.1, EMJ66525.1 fig|996802.3.peg.4830, fig|1049912.3.peg.620, fig|189518.1.peg.980, fig|996803.3.peg.1295, fig|1218577.3.peg.3595, fig|1218579.3.peg.5510, fig|1049930.3.peg.1376, fig|1001588.3.peg.5401, fig|1218578.3.peg.3147, fig|1085541.3.peg.391, fig|1049911.3.peg.1922 505 515 yes 1890424 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 607711, 1030841 Neisseria wadsworthii, Neisseria wadsworthii 9715 Bacteria UP000005336 496406375, 349797583 EGZ51341.1 WP_009115239.1 fig|1030841.3.peg.99 621 624 yes 1890425 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39947 Oryza sativa Japonica Group Plants UP000000763 UP000059680 115454593, 108710406, 215767700, 215697043, 113549368 ABF98201.1 NP_001050897.1 550 639 yes 1890426 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537007 Blautia hansenii DSM 20583 Bacteria UP000003755 260542458 EEX23027.1 437 437 yes 1890427 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 207949 Bermanella marisrubri Bacteria UP000004263 94425988 EAT10985.1 fig|207949.3.peg.2202 620 632 yes 1890428 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262930 Prevotella sp. CAG:5226 Environmental samples UP000018184 547498992, 524283329 WP_022101086.1 564 564 yes 1890429 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 245836 Nocardiopsis salina Bacteria 516208220 WP_017612183.1 549 553 yes 1890430 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626940, 626939 Phascolarctobacterium sp. YIT 12068, Phascolarctobacterium sp. YIT 12067 Bacteria UP000004923 496436746, 322413912 EFY04748.1 WP_009145591.1 433 433 yes 1890431 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 124, 314230 Blastopirellula marina, Blastopirellula marina DSM 3645 Bacteria UP000004358 488728889, 87287981 EAQ79879.1 WP_002652320.1 fig|314230.3.peg.1219 442 445 yes 1890432 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 997883, 997882 Bacteroides fragilis, Bacteroides fragilis CL07T12C05, Bacteroides fragilis CL07T00C01 Bacteria UP000036847, UP000003879, UP000004181 492264182, 392701751, 387778467 EIY94905.1, EIK40562.1 WP_005793499.1 fig|997883.3.peg.2841, fig|997882.3.peg.198 564 564 yes 1890433 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 540 540 yes 1890434 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1082, 1316936 Phaeospirillum fulvum, Phaeospirillum fulvum MGU-K5 Bacteria UP000015350 544701079, 528191451 EPY01757.1 WP_021132168.1 608 613 yes 1890435 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 669 Vibrio harveyi Bacteria UP000067422 516428207 WP_017817569.1 640 646 yes 1890436 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 247490 planctomycete KSU-1 Bacteria UP000002985 386404391 fig|247490.3.peg.1683 422 443 yes 1890437 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 63745, 580332 Sideroxydans lithotrophicus, Sideroxydans lithotrophicus ES-1 Bacteria UP000001625 502796060, 291585482 ADE13140.1 WP_013031036.1 fig|580332.3.peg.1385 622 623 yes 1890438 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1151120 Bacillus sp. 105MF Bacteria 517594942 WP_018765150.1 586 586 yes 1890439 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 566679 Bradyrhizobium sp. ORS375 Bacteria UP000003055 496322314, 365286326 WP_009031492.1 fig|566679.3.peg.6334 622 633 yes 1890440 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 496, 997348 Neisseria macacae, Neisseria macacae ATCC 33926 Bacteria UP000004982 489874771, 339887301 EGQ76872.1 WP_003778283.1 625 633 yes 1890441 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 471 Acinetobacter calcoaceticus Bacteria UP000032475 515959428 WP_017390011.1 621 625 yes 1890442 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1196346, 1232184, 1173443, 1173422, 1182192, 1182185, 1196349, 1173464, 1173466, 1173462, 1173473, 1173474, 1173425, 1173475, 1173428, 1173426, 1173476, 1173454, 1173429, 1173460, 1173430, 1173432, 1173433, 1173431, 1173477, 1173451, 1173434, 1173458, 1173436, 1173437, 1173439, 1173461, 1173438, 1173440, 1173469, 1173450, 1173455, 1173441, 1173442, 1173420, 1173447, 1173444, 1173446, 1173456, 1173423, 1173448, 1173478, 1173449, 1182175, 1182173, 1182174, 1182176, 1182178, 1182177, 1182180, 1182186, 1182181, 1182182, 1182184, 1182183, 1182187, 1182188, 1182189, 1182190, 1182191, 1183388, 1183387, 1182193, 1183389, 1183390, 1183392, 1183393, 1208626, 1196348, 1196347, 1208624, 1208625, 1208628, 1208627, 1208629, 1208623, 1208630, 1208622, 1173421, 1173459, 1173465, 1173453, 1173457, 1182172, 1183391, 1173463, 1124925, 1173427 Salmonella enterica, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001087, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001591, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000220, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000229, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000962, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000956, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001090, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000178, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000180, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000182, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000184, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000186, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000185, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000187, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000190, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000188, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000195, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000192, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000193, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000194, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000196, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000201, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000204, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000199, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000202, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000208, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000205, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000206, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000209, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000210, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000214, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000212, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000213, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000215, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000216, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000221, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000218, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000217, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000219, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000222, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000227, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000223, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000225, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000228, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000231, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000230, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000232, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000233, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000680, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000662, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000669, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000700, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000753, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000752, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000951, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000755, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000952, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000953, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000955, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000954, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000957, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000958, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000959, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000960, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000961, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000965, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000964, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000963, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000966, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000967, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000969, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000970, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001105, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001089, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001088, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001099, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001102, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001109, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001108, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001112, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001140, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001115, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN001118, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000226, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000211, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000179, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000203, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000191, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000661, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000968, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000183, Salmonella enterica subsp. enterica serovar Bareilly str. ATCC 9115, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000189 Bacteria UP000054489, UP000027468, UP000032122, UP000029687, UP000029740, UP000029731, UP000029686, UP000029720, UP000029199, UP000029190, UP000029178, UP000029155, UP000029197, UP000029201, UP000029189, UP000029188, UP000029198, UP000029183, UP000029150, UP000029186, UP000029159, UP000029160, UP000029157, UP000029175, UP000029166, UP000029142, UP000029143, UP000029182, UP000029151, UP000029163, UP000029148, UP000029162, UP000029169, UP000029149, UP000029167, UP000029174, UP000029144, UP000029152, UP000029158, UP000029200, UP000029193, UP000029177, UP000029173, UP000029192, UP000029141, UP000029195, UP000029168, UP000029196, UP000029140, UP000029176, UP000029164, UP000029179, UP000029145, UP000029146, UP000029172, UP000029191, UP000029154, UP000029156, UP000029185, UP000029291, UP000029147, UP000029271, UP000029301, UP000029255, UP000029269, UP000029318, UP000029287, UP000029263, UP000029277, UP000029328, UP000029294, UP000029281, UP000029323, UP000029319, UP000029297, UP000029312, UP000029321, UP000029333, UP000029332, UP000029296, UP000029258, UP000029311, UP000029253, UP000029279, UP000027458, UP000027462, UP000027431, UP000027445, UP000027474, UP000027435, UP000027459, UP000017582, UP000017486, UP000014989 526090050, 816130939, 753565573, 689486039, 689481155, 689476263, 689469330, 689465129, 677957532, 677955707, 677951926, 677943013, 677937322, 677933656, 677929266, 677925937, 677924829, 677916156, 677915576, 677907837, 677904945, 677894831, 677887060, 677883168, 677883099, 677873091, 677870737, 677869957, 677858767, 677854881, 677848052, 677839626, 677838944, 677836941, 677830347, 677826440, 677824697, 677813684, 677812670, 677805090, 677800213, 677796743, 677789942, 677782339, 677774382, 677771960, 677770955, 677769586, 677763131, 677744656, 677744631, 677740026, 677729459, 677725963, 677725046, 677711580, 677710006, 677709388, 677701141, 677700508, 677695562, 677683574, 677678354, 677677573, 677669913, 677667629, 677662264, 677660888, 677656099, 677647050, 677647026, 677643102, 677633033, 677629882, 677625970, 677623470, 677619659, 677610184, 677602217, 677601378, 677595269, 677588546, 677583483, 677581479, 646683931, 646678938, 646666911, 646660114, 646656811, 646649832, 646648112, 554334720, 554303753, 523814904 KDR07460.2, KIO79080.1, KGE47702.1, KGE43197.1, KGE38894.1, KGE32882.1, KGE28886.1, KFU66675.1, KFU64945.1, KFU61386.1, KFU52901.1, KFU47479.1, KFU43934.1, KFU39754.1, KFU36541.1, KFU35476.1, KFU27607.1, KFU27096.1, KFU19782.1, KFU17094.1, KFU07532.1, KFU00123.1, KFT96440.1, KFT96380.1, KFT86995.1, KFT84900.1, KFT84197.1, KFT73710.1, KFT70188.1, KFT63694.1, KFT55528.1, KFT54876.1, KFT52961.1, KFT46738.1, KFT43043.1, KFT41447.1, KFT30760.1, KFT29827.1, KFT22745.1, KFT18291.1, KFT15011.1, KFT08697.1, KFT01899.1, KFS94885.1, KFS92641.1, KFS91746.1, KFS90519.1, KFS84977.1, KFS67902.1, KFS67882.1, KFS63754.1, KFS53706.1, KFS50398.1, KFS49508.1, KFS36759.1, KFS35266.1, KFS34682.1, KFS27003.1, KFS26407.1, KFS22076.1, KFS11056.1, KFS06116.1, KFS05450.1, KFR98132.1, KFR95994.1, KFR90899.1, KFR89595.1, KFR85074.1, KFR77062.1, KFR77042.1, KFR73737.1, KFR64679.1, KFR61956.1, KFR58201.1, KFR55799.1, KFR52681.1, KFR44354.1, KFR37248.1, KFR36512.1, KFR31123.1, KFR24818.1, KFR19965.1, KFR18125.1, KDR02939.1, KDQ99350.1, KDQ89874.1, KDQ85132.1, KDQ82758.1, KDQ76549.1, KDQ74986.1, ESH71951.1, ESH39915.1, AGQ60673.1 WP_020839715.1 626 631 yes 1890443 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 663, 674977 Vibrio alginolyticus, Vibrio alginolyticus 40B Bacteria UP000066605, UP000006248 491528620, 269828639 EEZ82897.1 WP_005386245.1 640 646 yes 1890444 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1315967 Anoxybacillus flavithermus NBRC 109594 Bacteria UP000013057 479333987 fig|1315967.3.peg.1890 573 582 yes 1890445 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410620 Shinella zoogloeoides DD12 Bacteria UP000017832 631492015, 601177151 EYR78718.1 WP_024271319.1 600 607 yes 1890446 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 155900 uncultured organism Environmental samples 534502899 AGU11621.1 603 618 yes 1890447 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1348662 Corynebacterium argentoratense DSM 44202 Bacteria UP000016943 533215041 AGU14369.1 564 579 yes 1890448 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158179 Thioalkalivibrio sp. ALE28 Bacteria 517708020 WP_018878228.1 627 629 yes 1890449 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1123867 SAR86 cluster bacterium SAR86B Bacteria UP000010116 526786407, 400759470 EJP73652.1 WP_020857831.1 584 584 yes 1890450 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 294, 1038923, 994484 Pseudomonas fluorescens, Pseudomonas fluorescens Q8r1-96, Pseudomonas brassicacearum subsp. brassicacearum NFM421 Bacteria UP000060991, UP000006009, UP000006692 489289606, 757240276, 388008989, 327375309 KIR13737.1, EIK70240.1, AEA66659.1 WP_003197160.1 fig|994484.3.peg.551, fig|1038923.3.peg.547, fig|1085031.4.peg.1028 628 629 yes 1890451 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 75659 Duganella zoogloeoides Bacteria 518767079 WP_019924368.1 638 638 yes 1890452 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81408, 1220594 Geobacillus caldoxylosilyticus, Geobacillus caldoxylosilyticus NBRC 107762 Bacteria UP000023561 755056657, 611292193 WP_042408786.1 572 573 yes 1890453 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 337191 Gordonia sp. KTR9 Bacteria UP000003281 403643915 AFR47155.1 fig|337191.3.peg.691 422 880 no 1890454 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444174, 1444199, 1444146, 1444075, 1444281, 1444090, 1444269, 1444211, 1444239, 1444279, 1444143, 1444171, 1444137, 1444054, 1444156, 1444181, 1444205, 1444097, 1444232, 1444068, 1444120, 1444194, 1444094, 1444148, 1444079, 1444038, 1444036, 1444051, 1444092, 1444106, 1444132, 1444160, 1116186, 1125652 Escherichia coli, Escherichia coli 6-537-08_S3_C2, Escherichia coli 6-537-08_S3_C3, Escherichia coli 6-537-08_S3_C1, Escherichia coli 7-233-03_S1_C2, Escherichia coli 6-175-07_S4_C3, Escherichia coli 6-319-05_S1_C2, Escherichia coli 5-172-05_S4_C3, Escherichia coli 5-172-05_S4_C1, Escherichia coli 5-172-05_S4_C2, Escherichia coli 3-373-03_S4_C3, Escherichia coli 4-203-08_S3_C1, Escherichia coli 4-203-08_S3_C2, Escherichia coli 3-020-07_S3_C1, Escherichia coli 3-020-07_S1_C1, Escherichia coli 2-474-04_S3_C2, Escherichia coli 2-222-05_S3_C3, Escherichia coli 2-210-07_S4_C1, Escherichia coli 2-210-07_S1_C3, Escherichia coli 2-177-06_S4_C2, Escherichia coli 2-177-06_S1_C2, Escherichia coli 2-156-04_S3_C1, Escherichia coli 3-373-03_S3_C3, Escherichia coli 2-052-05_S1_C3, Escherichia coli 2-011-08_S3_C2, Escherichia coli 1-182-04_S1_C2, Escherichia coli 2-052-05_S1_C1, Escherichia coli 2-005-03_S1_C1, Escherichia coli 1-182-04_S1_C1, Escherichia coli 2-005-03_S1_C3, Escherichia coli 1-182-04_S1_C3, Escherichia coli 1-110-08_S3_C1, Escherichia coli 1-110-08_S3_C2, Escherichia coli P0304816.10, Escherichia coli 179100 Bacteria UP000036210, UP000027945, UP000028063, UP000028031, UP000028032, UP000028120, UP000027869, UP000028043, UP000028147, UP000028014, UP000027689, UP000027630, UP000027698, UP000027938, UP000027748, UP000028087, UP000027810, UP000027717, UP000027797, UP000027839, UP000027873, UP000027817, UP000028113, UP000027837, UP000027288, UP000027207, UP000027174, UP000023875, UP000024162, UP000024101, UP000024289, UP000021226, UP000022114, UP000012216, UP000012295 486030835, 660223641, 660187770, 660179359, 660167310, 660151756, 660116514, 660061965, 660038342, 660023850, 660023411, 660020902, 660008915, 652228510, 652215484, 652182689, 652067354, 651810086, 651771452, 651762734, 651749466, 651718176, 650048583, 649985350, 632183939, 632170548, 632165077, 611138504, 611128427, 611110658, 611090636, 598714125, 598711818, 477247146, 477046557 KEN15221.1, KEM80310.1, KEM72058.1, KEM60249.1, KEM45312.1, KEM11213.1, KEL57817.1, KEL36234.1, KEL22062.1, KEL21640.1, KEL19368.1, KEL07633.1, KDZ35477.1, KDZ23241.1, KDY92297.1, KDX83857.1, KDW85623.1, KDW48591.1, KDW40424.1, KDW27700.1, KDV97671.1, KDT71342.1, KDT10661.1, KDA77924.1, KDA66235.1, KDA61283.1, EZK37525.1, EZK27793.1, EZK10782.1, EZJ91774.1, EYE18535.1, EYE16382.1, ENF20533.1, END29879.1 WP_001504932.1 fig|1116186.3.peg.4312, fig|1125652.3.peg.4487 626 631 yes 1890455 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 993513 Escherichia coli, Escherichia coli cloneA_i1 Bacteria UP000036210, UP000004615 485736531, 355349333 EHF98541.1 WP_001363762.1 fig|993513.3.peg.4250 626 631 yes 1890456 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28126, 873513 Prevotella buccae, Prevotella buccae ATCC 33574 Bacteria UP000003112 490476514, 315249379 EFU29396.1 WP_004346901.1 532 536 yes 1890457 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 51589, 634497, 1417673 Haloarcula hispanica, Haloarcula hispanica ATCC 33960, Haloarcula hispanica N601 Archaea UP000005629, UP000018572 503806592, 344212054, 564122329, 343783409 AHB66151.1, AEM57386.1 WP_014040586.1, YP_004796374.1 V5TLH1, G0HTX9 V5TLH1_HALHI, G0HTX9_HALHT 455 480 yes 1890458 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 457395 Bacteroides sp. 9_1_42FAA Bacteria UP000005103 229455906 EEO61627.1 fig|457395.6.peg.2558 565 565 yes 1890459 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 889247 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni ATCC 33560 Bacteria UP000065538, UP000005609 488971455, 380625067, 777189485 EIB43675.1 WP_002882387.1 fig|889247.3.peg.1414 430 430 yes 1890460 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33934, 1267580 Anoxybacillus flavithermus, Anoxybacillus flavithermus TNO-09.006 Bacteria UP000031249, UP000024388 491029216, 432000875 ELK21766.1 WP_004890904.1 fig|1267580.3.peg.1652 561 562 yes 1890461 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 239984 Nocardiopsis ganjiahuensis Bacteria 516156298 WP_017585079.1 551 555 yes 1890462 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 101564 Pseudomonas alcaliphila Bacteria 516274677 WP_017678640.1 627 627 yes 1890463 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1076, 652103 Rhodopseudomonas palustris, Rhodopseudomonas palustris DX-1 Bacteria UP000032515, UP000001402 503266877, 315600856 ADU43391.1 WP_013501538.1 fig|652103.3.peg.4116 656 666 yes 1890464 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 935588 Neisseria meningitidis, Neisseria meningitidis M01-240355 Bacteria UP000050419, UP000007099 504395211, 325204990 ADZ00444.1 WP_014582313.1 fig|935588.3.peg.2701 625 633 yes 1890465 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2880 Ectocarpus siliculosus Plants UP000002630 298708972 552 640 yes 1890466 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 659243 Bacillus sp. PD-A10 Bacteria 515505204 WP_016938458.1 590 590 yes 1890467 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1005400 Escherichia coli, Escherichia coli 90.0091 Bacteria UP000036210, UP000010175 486012969, 427217146 EKV86218.1 WP_001502809.1 fig|1005400.3.peg.5165 626 631 yes 1890468 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 698956 Gardnerella vaginalis 1400E Bacteria UP000004884 388058160 EIK80958.1 fig|698956.3.peg.910 609 881 yes 1890469 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 766154 Shigella flexneri 1235-66 Bacteria 391306367 EIQ64124.1 fig|766154.3.peg.7777 626 632 yes 1890470 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29282, 1227453 Haloarcula japonica, Haloarcula japonica DSM 6131 Archaea 490730048, 445779731 EMA30647.1 WP_004592432.1 M0LAQ0 M0LAQ0_HALJP 455 480 yes 1890471 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 32008, 1097668, 758796 Burkholderia sp. YI23, Burkholderia sp. RPE67 Bacteria UP000006801, UP000031658 503956938, 357935141, 636793893 AET88700.1 WP_014190932.1 fig|1097668.3.peg.947 642 643 yes 1890472 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 283811, 446470 Stackebrandtia nassauensis, Stackebrandtia nassauensis DSM 44728 Bacteria UP000000844 502781222, 290567662 ADD40627.1 WP_013016198.1 fig|446470.4.peg.4529 515 516 yes 1890473 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 125, 530564 Pirellula staleyi, Pirellula staleyi DSM 6068 Bacteria UP000001887 502674557, 283437612 ADB16054.1 WP_012910317.1 fig|530564.3.peg.1428 447 451 yes 1890474 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 243090, 265488, 1263868, 1263867, 993516, 993517, 991778 Rhodopirellula baltica SH 1, Rhodopirellula europaea SH398, Rhodopirellula europaea 6C, Rhodopirellula baltica SWK14, Rhodopirellula baltica SH28, Rhodopirellula baltica WH47 Bacteria UP000001025 UP000001025, UP000011996, UP000011529, UP000010959, UP000007993, UP000006222 32474698, 494541543, 460275395, 448883916, 436441762, 408497728, 327540729, 47606118, 32445237 EMI29156.1, EMB14423.1, ELP34954.1, EKK02247.1, EGF27298.1 NP_867692.1, WP_007326663.1 Q7UP26 THIC_RHOBA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 558087 fig|1263867.3.peg.5201, fig|1263868.3.peg.287, fig|243090.1.peg.4032, fig|991778.3.peg.2918, fig|993517.3.peg.2632, fig|993516.3.peg.1010 439 441 yes 1890475 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1764 Mycobacterium avium Bacteria 518565680 WP_019735887.1 548 550 yes 1890476 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 1161744 Bifidobacterium longum, Bifidobacterium longum subsp. longum 1-6B Bacteria UP000028505, UP000006410 494115638, 386412090 EIJ26781.1 WP_007055420.1 fig|1161744.3.peg.652 635 917 yes 1890477 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 374, 754504 Bradyrhizobium japonicum SEMIA 5080 Bacteria UP000024900 654718655, 694287786 KGJ67068.1 WP_028176294.1 623 632 yes 1890478 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470 Acinetobacter baumannii Bacteria UP000028632 487920818 WP_001994284.1 277 277 yes 1890479 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1208663 Cronobacter sakazakii 701 Bacteria UP000009355 426320970 404 407 yes 1890480 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 136094, 638303 Thermocrinis albus, Thermocrinis albus DSM 14484 Bacteria UP000002043 502757063, 289182397 ADC89641.1 WP_012992047.1 fig|638303.3.peg.1002 452 455 yes 1890481 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116192 Escherichia coli, Escherichia coli P0305260.3 Bacteria UP000036210, UP000012253 487372440, 477328430 ENF98102.1 WP_001646083.1 fig|1116192.3.peg.4251 626 631 yes 1890482 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630 630 yes 1890483 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 388384 Pseudoalteromonas sp. BSi20652 Bacteria UP000005499 495446424, 357918611 WP_008171118.1 fig|388384.3.peg.3064 645 650 yes 1890484 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1265656 Salmonella enterica, Salmonella enterica subsp. enterica serovar Agona str. 57.A.08 Bacteria UP000054489, UP000013453 493949565, 485005046 WP_006893464.1 626 631 yes 1890485 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 338, 1118965, 1127439 Xanthomonas axonopodis pv. malvacearum str. GSPB1386, Xanthomonas axonopodis pv. malvacearum str. GSPB2388 Bacteria UP000001337, UP000001144 492652475, 410707462, 410702007 EKQ65914.1, EKQ60519.1 WP_005911999.1 fig|1127439.3.peg.2320, fig|1118965.3.peg.734 624 625 yes 1890486 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 79885, 398511 Bacillus pseudofirmus, Bacillus pseudofirmus OF4 Bacteria UP000001544 502725841, 288545669 ADC49552.1 WP_012960825.1 fig|398511.4.peg.1450 592 592 yes 1890487 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 103855, 1331255, 1331256, 1331259, 1331262, 1331261 Bordetella hinzii, Bordetella hinzii 1277, Bordetella hinzii 4161, Bordetella hinzii CA90 BAL1384, Bordetella hinzii OH87 BAL007II, Bordetella hinzii L60 Bacteria UP000036132, UP000026696, UP000026615, UP000025383, UP000025748, UP000026379 657873373, 625332875, 625329052, 625314807, 625306187, 625305537 KCB47227.1, KCB43480.1, KCB30006.1, KCB21788.1, KCB21164.1 WP_029577935.1 636 637 yes 1890488 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 123841, 537970 Helicobacter canadensis, Helicobacter canadensis MIT 98-5491 Bacteria UP000002987 493706164, 313131050, 253511208 EFR48667.1, EES89867.1 WP_006655861.1 fig|537970.5.peg.2270 442 443 yes 1890489 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1101195 Methylophilaceae bacterium 11 Bacteria UP000022668 643538181, 577705486 EUJ11632.1 WP_025225076.1 624 627 yes 1890490 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 326544, 1129794 Glaciecola psychrophila, Glaciecola psychrophila 170 Bacteria UP000006323 494909834, 469487532, 410168917 AGH47385.1 WP_007635875.1 fig|1129794.3.peg.864 646 654 yes 1890491 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168657, 547146, 547144, 547145, 547143 Hydrogenobaculum sp. SN, Hydrogenobaculum sp. HO, Hydrogenobaculum sp. SHO, Hydrogenobaculum sp. 3684 Bacteria UP000011888, UP000011725, UP000031630, UP000032381 505232607, 469932961, 452882732, 334105446, 333119029 AGH93738.1, AGG15436.1, AEG46791.1, AEF19503.1 WP_015419709.1 fig|547143.3.peg.1127, fig|547144.3.peg.1129, fig|547146.3.peg.189 450 453 yes 1890492 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 212695 uncultured Flavobacteria bacterium Environmental samples 377345042 618 618 yes 1890493 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204042 Dickeya zeae Bacteria 518684915 WP_019846608.1 629 653 yes 1890494 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 296 Pseudomonas fragi Bacteria UP000065958 498342103 WP_010656259.1 627 629 yes 1890495 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 99007, 698757 Pyrobaculum oguniense, Pyrobaculum oguniense CH Archaea UP000009062 504114229, 379005710, 375161163 AFA40775.1 WP_014348215.1, YP_005261382.1 H6QBY3 H6QBY3_PYROT 421 434 no 1890496 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33047, 1094497 Bartonella vinsonii, Bartonella vinsonii subsp. berkhoffii str. Winnie Bacteria UP000011726 505211785, 451901108 AGF75570.1 WP_015398887.1 fig|1094497.3.peg.499 602 611 yes 1890497 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1195457 Streptomyces sp. SM8 Bacteria UP000006751 406691028 EKC94799.1 fig|1195457.3.peg.2286 595 597 yes 1890498 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84405, 760142 Hippea maritima, Hippea maritima DSM 10411 Bacteria UP000008139 503447392, 327181833 AEA34014.1 WP_013682053.1 fig|760142.3.peg.1064 428 428 yes 1890499 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444037 Escherichia coli, Escherichia coli 2-011-08_S1_C1 Bacteria UP000036210, UP000027281 693171571, 632159068 KDA56079.1 WP_032303891.1 626 631 yes 1890500 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 628, 1437823, 406817 Xenorhabdus nematophila, Xenorhabdus nematophila AN6/1, Xenorhabdus nematophila ATCC 19061 Bacteria UP000031446, UP000032806, UP000008075 502948376, 733161052, 297628109 WP_013183352.1 625 663 yes 1890501 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1384060 Rhodococcus sp. P27 Bacteria UP000016008 536662234 ERB54164.1 534 543 yes 1890502 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262888 Eubacterium sp. CAG:274 Environmental samples UP000017904 547840583, 524478556 WP_022248164.1 438 440 yes 1890503 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310894 Acinetobacter baumannii, Acinetobacter baumannii 44895_10 Bacteria UP000028632, UP000021600 691093934, 593878672 EXT35270.1 WP_032022786.1 621 625 yes 1890504 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1763, 1796, 1802 Mycobacterium senegalense, Mycobacterium farcinogenes Bacteria UP000035252, UP000030709 738438159, 828271184, 823099010, 633839436 KLO52203.1, KLI08471.1 WP_036389408.1 541 543 yes 1890505 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298 516483311 WP_017871755.1 600 603 yes 1890506 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204037, 561229 Dickeya zeae Ech1591 Bacteria UP000002735 506328453, 247540049 ACT08670.1 WP_015848172.1 fig|1224148.3.peg.8234, fig|561229.3.peg.3940 631 655 yes 1890507 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3847 Glycine max Plants UP000008827 UP000008827 356566163 XP_003551304.1 548 647 yes 1890508 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262786 Clostridium sp. CAG:264 Environmental samples UP000018342 547202580, 524081011 WP_021943643.1 349 356 no 1890509 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1201294 Methanoculleus bourgensis MS2 Archaea UP000009007 396939153 I7J909 I7J909_METBM 413 438 no 1890510 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 379064, 755178 Cyanobacterium aponinum, Cyanobacterium aponinum PCC 10605 Bacteria UP000010480 505031052, 428682955 AFZ52422.1 WP_015218154.1 fig|755178.3.peg.282 457 460 yes 1890511 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76020 Amycolatopsis alba Bacteria 522120691 WP_020631900.1 545 547 yes 1890512 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310776 Acinetobacter baumannii, Acinetobacter baumannii 1413735 Bacteria UP000028632, UP000020199 691111667, 593525947 EXR10604.1 WP_032032826.1 621 625 yes 1890513 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158756 Thioalkalivibrio sp. ALJ7 Bacteria 516873069 WP_018141137.1 626 629 yes 1890514 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 983544 Lacinutrix sp. 5H-3-7-4 Bacteria UP000008297 503636183, 334727342 AEH01480.1 WP_013870259.1 fig|983544.3.peg.1644 620 620 yes 1890515 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626938, 762983 Succinatimonas hippei, Succinatimonas hippei YIT 12066 Bacteria UP000018458 496435196, 322415631 EFY06377.1 WP_009144043.1 474 504 yes 1890516 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 366648, 427082 Xanthomonas fuscans, Xanthomonas fuscans subsp. aurantifolii str. ICPB 10535 Bacteria UP000005603 495248044, 292604026 EFF47423.1 WP_007972803.1 624 625 yes 1890517 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053204, 1053201 Bacillus cereus, Bacillus cereus HuA2-9, Bacillus cereus HuA2-1 Bacteria UP000036076, UP000013994, UP000004136 488067697, 500288783, 402445577 EOO12976.1, EJV77446.1 WP_002139094.1 fig|1053204.3.peg.5007, fig|1053201.3.peg.4928 586 586 yes 1890518 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 160386, 1110505 Corynebacterium casei, Corynebacterium casei UCMA 3821 Bacteria UP000004840 493875094, 356609090 WP_006821516.1 590 604 yes 1890519 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1226754 Paenibacillus sp. FSL R5-192 Bacteria UP000019041 573541284 ETT40225.1 596 605 yes 1890520 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294 Pseudomonas fluorescens Bacteria UP000060991 515552755 WP_016985681.1 628 629 yes 1890521 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287182 Mesorhizobium sp. L48C026A00 Bacteria UP000019863 563846430, 563187966 ESZ11074.1 WP_023802514.1 596 611 yes 1890522 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 52226, 500635 Mitsuokella multacida, Mitsuokella multacida DSM 20544 Bacteria UP000003671 492431194, 260848189 EEX68196.1 WP_005842309.1 434 435 yes 1890523 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2189, 880724 Methanotorris igneus, Methanotorris igneus Kol 5 Archaea UP000009227 503564839, 333751233 AEF96312.1 WP_013798915.1 F6BCV1 F6BCV1_METIK 426 426 yes 1890524 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29484, 349966 Yersinia frederiksenii, Yersinia frederiksenii ATCC 33641 Bacteria UP000044306, UP000005500 490850352, 685055568, 238721292 KGA46721.1, EEQ12967.1 WP_004712414.1 fig|349966.3.peg.4069 640 664 yes 1890525 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 517433 Pantoea sp. aB Bacteria UP000004279 496209225, 304353164 EFM17546.1 WP_008927147.1 631 640 yes 1890526 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40216, 903900 Acinetobacter radioresistens, Acinetobacter radioresistens WC-A-157 Bacteria UP000018456 491548169, 400205124 EJO36105.1 WP_005405783.1 fig|903900.3.peg.693 626 630 yes 1890527 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 110321 Sinorhizobium medicae Bacteria 516640975 WP_018012554.1 597 610 yes 1890528 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1248727 endosymbiont of unidentified scaly snail isolate Monju Bacteria UP000015562 759382123, 530671378 WP_043108530.1 627 630 yes 1890529 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37482 Laceyella sacchari Bacteria 550989557 WP_022736987.1 582 582 yes 1890530 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116061 Escherichia coli, Escherichia coli MP021017.5 Bacteria UP000036210, UP000012376 487428981, 476051783 EMU76623.1 WP_001688139.1 fig|1116061.3.peg.4484 626 631 yes 1890531 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 35701, 498761 Heliobacterium modesticaldum, Heliobacterium modesticaldum Ice1 Bacteria UP000008550 501240112, 167592882 ABZ84630.1 WP_012283130.1 fig|498761.3.peg.1861 453 465 no 1890532 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 378548, 983920 Novosphingobium nitrogenifigens, Novosphingobium nitrogenifigens DSM 19370 Bacteria UP000004728 495341884, 326207734 EGD58545.1 WP_008066618.1 618 620 yes 1890533 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33060, 349967 Yersinia mollaretii, Yersinia mollaretii ATCC 43969 Bacteria UP000038753, UP000003027 491015068, 238717490 EEQ09332.1 WP_004876776.1 fig|349967.3.peg.3228 654 687 yes 1890534 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1161942, 213810 Ruminococcus champanellensis, Ruminococcus sp. 18P13 Bacteria UP000007054 505371331, 291544417 WP_015558433.1 436 436 yes 1890535 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 199, 1242969 Campylobacter concisus, Campylobacter concisus ATCC 51562 Bacteria UP000066049, UP000016627 544657782, 543206243 ERJ25447.1 WP_021091419.1 432 432 yes 1890536 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 1144332, 1144321 Pseudomonas sp. GM50, Pseudomonas sp. GM102 Bacteria UP000007513, UP000007514 495177794, 398184531, 398108944 EJM71978.1, EJL98889.1 WP_007902586.1 fig|1144321.3.peg.3622, fig|1144332.3.peg.12 628 629 yes 1890537 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1345697 Geobacillus sp. JF8 Bacteria UP000015500 530781817, 530456196 AGT30772.1 WP_020958583.1 562 562 yes 1890538 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29507, 1240687 Leptospira kirschneri, Leptospira kirschneri serovar Bulgarica str. Nikolaevo Bacteria UP000011980 523624761, 463363323 EMK25024.1 WP_020763002.1 fig|1240687.3.peg.1371 436 490 yes 1890539 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396858 Marinobacter sp. ES-1 Bacteria UP000035072 550664106 ERP89945.1 585 585 yes 1890540 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314254 Oceanicaulis alexandrii HTCC2633 Bacteria UP000006011 497487638, 83852127 EAP89981.1 WP_009801836.1 fig|314254.3.peg.2379 621 630 yes 1890541 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 387343, 797210 Halopiger xanaduensis, Halopiger xanaduensis SH-6 Archaea UP000006794 503647311, 336255273, 335339262 AEH38501.1 WP_013881387.1, YP_004598380.1 F8D369 F8D369_HALXS 461 480 yes 1890542 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 519089557 WP_020245432.1 626 631 yes 1890543 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901 Salmonella enterica Bacteria UP000054489 446030431 WP_000108286.1 626 631 yes 1890544 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 226186, 818 Bacteroides thetaiotaomicron VPI-5482, Bacteroides thetaiotaomicron Bacteria UP000001414 UP000001414, UP000066931 29346060, 499419908, 29337954, 47606164 AAO75757.1 NP_809563.1, WP_011107372.1 Q8AA15 THIC_BACTN Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 350178 fig|226186.1.peg.650 565 565 yes 1890545 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553190 Gardnerella vaginalis 409-05 Bacteria UP000001888 283441855 ADB14321.1 fig|553190.4.peg.780, fig|682148.3.peg.221 602 885 yes 1890546 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 560405189 WP_023622725.1 640 646 yes 1890547 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 77133 uncultured bacterium Environmental samples UP000041370 406895986 EKD40398.1 385 408 no 1890548 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1127483 Cupriavidus basilensis OR16 Bacteria UP000005808 373097821 EHP38942.1 fig|1127483.3.peg.6889 486 486 yes 1890549 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1482 Virgibacillus halodenitrificans Bacteria 635572020 609 612 yes 1890550 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 205844, 1088721 Novosphingobium pentaromativorans, Novosphingobium pentaromativorans US6-1 Bacteria UP000029913 494069909, 698181439, 357600261 AIT80964.1, EHJ61959.1 WP_007011971.1 fig|1088721.3.peg.1043 618 626 yes 1890551 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 420402 Marinobacterium rhizophilum Bacteria 522172518 WP_020681067.1 625 626 yes 1890552 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1286632 Zhouia amylolytica AD3 Bacteria UP000018850 568803270 ETN94744.1 582 582 yes 1890553 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314266 Sphingomonas sp. SKA58 Bacteria UP000005395 497509008, 94422739 EAT07774.1 WP_009823206.1 fig|314266.4.peg.2068 623 631 yes 1890554 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 665959 Bacillus sp. 2_A_57_CT2 Bacteria UP000003283 496693984, 317394488 EFV75232.1 WP_009335527.1 594 594 yes 1890555 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 574560, 1221520 Photorhabdus temperata, Photorhabdus temperata subsp. temperata M1021 Bacteria UP000015813 544913076, 530711049 EQC01912.1 WP_021322849.1 619 642 yes 1890556 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1458425 Comamonadaceae bacterium A1 Bacteria UP000067461 780234033, 635595862 WP_045531436.1 636 643 yes 1890557 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 550674 Escherichia coli, Escherichia coli B093 Bacteria UP000036210, UP000003158 447199649, 371616156 EHO04524.1 WP_001276905.1 fig|550674.3.peg.4511 626 631 yes 1890558 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1513, 1231072 Clostridium tetani, Clostridium tetani 12124569 Bacteria UP000029689, UP000017784 557697371, 557604808, 557255509 WP_023437673.1, YP_008772919.1 347 347 yes 1890559 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 659, 1454202 Photobacterium phosphoreum, Photobacterium phosphoreum ANT220 Bacteria UP000032485, UP000019762 738901531, 758796339 WP_036788484.1 634 637 yes 1890560 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 550677 Escherichia coli, Escherichia coli B354 Bacteria UP000036210, UP000004683 447199643, 291468025 EFF10524.1 WP_001276899.1 626 631 yes 1890561 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1001989, 1403943, 869672 Escherichia coli, Escherichia coli PCN033, Escherichia coli DORA_A_5_14_21, Escherichia coli 97.0259 Bacteria UP000036210, UP000004770, UP000018853, UP000018743 447199642, 828391077, 566286451, 386155521 AKK50907.1, ETJ27511.1, EIH11872.1 WP_001276898.1 fig|1001989.3.peg.3971, fig|869672.4.peg.3942, fig|869678.3.peg.4256 626 631 yes 1890562 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446551, 1281115, 1281017, 1196033, 656393 Escherichia coli, Escherichia coli O119:H4 str. 03-3458, Escherichia coli HVH 188 (4-2356988), Escherichia coli HVH 79 (4-2512823), Escherichia coli SEPT362, Escherichia coli H299 Bacteria UP000036210, UP000023955, UP000016125, UP000016300, UP000011574, UP000005749 447199645, 838767612, 606962685, 535213632, 534815545, 449315660, 331077046 KLX50380.1, EYZ93491.1, EQT57547.1, EQP67086.1, EMD05798.1, EGI48262.1 WP_001276901.1 fig|656393.3.peg.5192, fig|1196033.3.peg.4268 626 631 yes 1890563 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444129, 1127356, 656437 Escherichia coli, Escherichia coli 5-366-08_S3_C1, Escherichia coli 4_1_47FAA, Escherichia coli TA143 Bacteria UP000036210, UP000027643, UP000004464, UP000002778 447199644, 746680913, 660093501, 373243273, 331057167 KIE72129.1, KEL88565.1, EHP62786.1, EGI29159.1 WP_001276900.1 fig|1127356.3.peg.5375, fig|656437.3.peg.4486 626 631 yes 1890564 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 983545 Glaciecola sp. 4H-3-7+YE-5 Bacteria UP000006544 503519452, 332174005 AEE23259.1 WP_013753864.1 fig|983545.3.peg.2456 620 626 yes 1890565 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 997296 Bacillus methanolicus PB1 Bacteria UP000010523 387587473 EIJ79795.1 589 589 yes 1890566 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 414 Methylococcus capsulatus Bacteria 515934067 WP_017364650.1 622 624 yes 1890567 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 521377, 1188261 Bacillus sp. GMBE72, Bacillus marmarensis DSM 21297 Bacteria UP000017170 550549389, 549460295 ERN51654.1 WP_022629525.1 592 592 yes 1890568 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 748280 Pseudogulbenkiania sp. NH8B Bacteria UP000001274 503852809, 345644952, 345642607 WP_014086803.1 fig|748280.3.peg.3914, fig|748280.3.peg.1613 635 636 yes 1890569 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 52022, 526227 Meiothermus silvanus, Meiothermus silvanus DSM 9946 Bacteria UP000001916 502921939, 296849293 ADH62308.1 WP_013156915.1 fig|526227.4.peg.1211 434 436 yes 1890570 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444188, 1116130 Escherichia coli, Escherichia coli 7-233-03_S3_C3, Escherichia coli 199900.1 Bacteria UP000036210, UP000027724, UP000012197 487631950, 660205610, 476668705 KEM97588.1, EMZ74502.1 WP_001739756.1 fig|1116130.3.peg.4518 626 631 yes 1890571 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1125965, 1391729 Brevundimonas sp. TAR-001, Brevundimonas abyssalis TAR-001 Bacteria UP000016569 545461725, 543414226 WP_021698414.1 617 622 yes 1890572 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571800 Psychrobacter sp. G Bacteria UP000014806 521255916, 521014659 AGP47719.1 WP_020442481.1 604 628 yes 1890573 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 653733 bacterium S5 Bacteria UP000002572 316946771 ADU66247.1 fig|653733.3.peg.1699 450 460 yes 1890574 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37919, 543736 Rhodococcus opacus, Rhodococcus opacus PD630 Bacteria UP000028488, UP000019682 491393862, 589068692, 356660151 AHK33551.1, EHI40515.1 WP_005251724.1 541 548 yes 1890575 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262978 Tannerella sp. CAG:118 Environmental samples UP000018396 547189990, 524056489 WP_021931772.1 373 374 yes 1890576 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1200300, 1184251 Thermogladius cellulolyticus, Thermogladius cellulolyticus 1633 Archaea UP000005270 504550584, 388526238 AFK51436.1 WP_014737686.1 I3TF98 I3TF98_THEC1 423 447 no 1890577 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 187303 Methylocystis sp. SC2 Bacteria UP000005263 504702700, 401772902 WP_014889802.1 fig|187303.17.peg.353 608 611 yes 1890578 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 485, 528359 Neisseria gonorrhoeae, Neisseria gonorrhoeae SK-92-679 Bacteria UP000027314, UP000002806 489797861, 268625469 EEZ57869.1 WP_003701752.1 624 633 yes 1890579 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262977 Sutterella sp. CAG:521 Environmental samples UP000018289 548255289, 524780618 WP_022472820.1 498 523 yes 1890580 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2724, 582402 Hirschia baltica, Hirschia baltica ATCC 49814 Bacteria UP000002745 506308325, 254043155 ACT59950.1 WP_015828100.1 fig|582402.5.peg.2317 622 630 yes 1890581 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262935 Prevotella sp. CAG:755 Environmental samples UP000018353 547008678, 524035078 WP_021909763.1 577 577 yes 1890582 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53413 Xanthomonas axonopodis Bacteria UP000054035 515724225 WP_017156825.1 624 625 yes 1890583 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1329825 Enterobacter sp. MGH 16 Bacteria UP000017317 556497555, 555206011 ESN48484.1 WP_023345242.1 626 631 yes 1890584 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375288, 658663, 563193, 1262912 Porphyromonas sp. 31_2, Parabacteroides sp. D13, Parabacteroides sp. CAG:2 Bacteria, Environmental samples UP000027795, UP000003956, UP000018197 496308254, 659417653, 256738895, 524400973 KEJ86753.1, EEU52220.1 WP_009017432.1 fig|563193.3.peg.1792 565 565 yes 1890585 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262919 Prevotella sp. CAG:1092 Environmental samples UP000017987 547255584, 524137708 WP_021990921.1 373 373 yes 1890586 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 146907 Desulfitobacterium sp. PCE1 Bacteria 518688690 WP_019850383.1 428 432 yes 1890587 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 635, 1288122, 718251, 498217, 1263550 Edwardsiella tarda C07-087, Edwardsiella tarda FL6-60, Edwardsiella tarda EIB202, Edwardsiella piscicida Bacteria UP000012006, UP000002230, UP000002634, UP000027363 502610039, 469761863, 304557610, 267983196, 635155553 AGH72281.1, ADM40274.1, ACY83025.1 WP_012847056.1 fig|1288122.3.peg.146, fig|718251.5.peg.152, fig|498217.4.peg.165 627 643 yes 1890588 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1078089 Bacteroides sp. HPS0048 Bacteria UP000017815 488623221, 482610814 EOA58850.1 WP_002559933.1 fig|1078089.3.peg.1926 564 564 yes 1890589 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28173, 1238447 Vibrio nigripulchritudo, Vibrio nigripulchritudo SFn118 Bacteria UP000033748, UP000018326 550275515, 548986066 WP_022602178.1 640 646 yes 1890590 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1261, 596329 Peptostreptococcus anaerobius, Peptostreptococcus anaerobius 653-L Bacteria UP000004206 488932918, 289156108 EFD04771.1 WP_002843993.1 436 436 yes 1890591 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1001601 Leptospira interrogans serovar Zanoni str. LT2156 Bacteria UP000012089 464172668 EMM97051.1 505 515 yes 1890592 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144340 Pseudomonas sp. GM84 Bacteria UP000007504 495370334, 398252443 EJN37632.1 WP_008095047.1 fig|1144340.3.peg.2734 627 628 yes 1890593 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286804, 679197 Segniliparus rugosus, Segniliparus rugosus ATCC BAA-974 Bacteria UP000004816 494732456, 316254910 EFV14205.1 WP_007468322.1 537 539 yes 1890594 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262691 Akkermansia sp. CAG:344 Environmental samples UP000017903 548176872, 524687324 WP_022398376.1 608 608 yes 1890595 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116059 Escherichia coli, Escherichia coli MP021017.3 Bacteria UP000036210, UP000012421 487443345, 476064625 EMU89200.1 WP_001690275.1 fig|1116059.3.peg.4704 626 631 yes 1890596 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1453472 Escherichia coli, Escherichia coli 1140 Bacteria UP000036210, UP000023917 693008011, 662002131 KEP78715.1 WP_032192209.1 626 631 yes 1890597 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1233100 Bacillus subtilis XF-1 Bacteria UP000011821 449027498 AGE62737.1 fig|1302650.3.peg.901, fig|1233100.3.peg.970 566 566 yes 1890598 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 343, 1195885 Xanthomonas translucens, Xanthomonas translucens pv. graminis ART-Xtg29 Bacteria UP000055854, UP000009390 497292828, 422795412 EKU24112.1 WP_009607045.1 fig|1195885.3.peg.2895 620 625 yes 1890599 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 881893, 1237149 Fulvivirga imtechensis, Fulvivirga imtechensis AK7 Bacteria UP000011135 497269400, 441434726 ELR68167.1 WP_009583617.1 fig|1237149.3.peg.5765 623 623 yes 1890600 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67760, 573063 Methanocaldococcus infernus, Methanocaldococcus infernus ME Archaea UP000002061 502864851, 295433910 ADG13081.1 WP_013099827.1 D5VR78 D5VR78_METIM 424 424 yes 1890601 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56730 Rhizobium gallicum Bacteria 517255721 WP_018444539.1 600 607 yes 1890602 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487732 Corynebacterium ulceribovis Bacteria 516654275 WP_018023264.1 560 563 yes 1890603 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 593750 Methanoregula formicicum SMSP Archaea UP000010824 432137238 AGB02165.1 L0HDV3 L0HDV3_METFS 405 461 no 1890604 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1490, 1233171 Clostridium bifermentans, Clostridium bifermentans ATCC 638 Bacteria UP000015688 545060142, 531766903 EQK43146.1 WP_021433237.1 437 437 yes 1890605 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28182, 1085540 Leptospira noguchii, Leptospira noguchii serovar Autumnalis str. ZUN142 Bacteria UP000012153 490575999, 464365031 EMO39409.1 WP_004441019.1 444 496 yes 1890606 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 88189 Thermus igniterrae Bacteria 516806752 WP_018110357.1 433 435 yes 1890607 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446762 Escherichia coli, Escherichia coli O86:H34 str. 99-3124 Bacteria UP000036210, UP000024092 693210531, 606539438 EYV93221.1 WP_032329490.1 626 631 yes 1890608 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446704, 754086 Escherichia coli, Escherichia coli O174:H8 str. 04-3038, Escherichia coli STEC_DG131-3 Bacteria UP000036210, UP000024282, UP000005491 447199646, 607004161, 345352638 EZA32774.1, EGW84883.1 WP_001276902.1 fig|754086.3.peg.5263 626 631 yes 1890609 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 698961 Gardnerella vaginalis 6119V5 Bacteria UP000033041 388064532 EIK87066.1 fig|698961.3.peg.1062 602 885 yes 1890610 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 723171 Vibrio sp. F10 Bacteria 515602044 WP_017034644.1 640 649 yes 1890611 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 509635 Pedobacter sp. V48 Bacteria UP000019145 576321907 ETZ21597.1 627 627 yes 1890612 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 527005 Yersinia ruckeri ATCC 29473 Bacteria UP000054139 238705720 EEP98114.1 646 669 yes 1890613 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 271417, 1268236 Aeromonas molluscorum, Aeromonas molluscorum 848 Bacteria UP000013526 492609481, 485942116 EOD54845.1 WP_005902167.1 fig|1268236.3.peg.2404 649 670 yes 1890614 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144304 Caulobacter sp. AP07 Bacteria UP000007300 494944394, 398037180 EJL30379.1 WP_007670422.1 fig|1144304.3.peg.3007 607 615 yes 1890615 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1133319, 1445607 Bacteroides reticulotermitis, Bacteroides reticulotermitis JCM 10512 Bacteria UP000019131 763299321, 576505862 WP_044159426.1 565 565 yes 1890616 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1095771 Ruminococcus sp. JC304 Bacteria 517990247 WP_019160455.1 435 436 yes 1890617 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 860, 469599 Fusobacterium periodonticum, Fusobacterium sp. 2_1_31 Bacteria UP000003301 496069647, 689620376 KGE62531.1 WP_008794154.1 fig|469599.3.peg.1069 433 433 yes 1890618 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 201089 uncultured Desulfobacterium sp. Environmental samples 308272414 432 432 yes 1890619 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 1203540 Bifidobacterium breve, Bifidobacterium breve HPH0326 Bacteria UP000029049, UP000014395 512635158, 512076441 EPD75650.1 WP_016462427.1 fig|1203540.3.peg.803 638 918 yes 1890620 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717, 1166015 Corynebacterium diphtheriae, Corynebacterium diphtheriae bv. intermedius str. NCTC 5011 Bacteria UP000033584, UP000003091 489950040, 387981723 EIK55268.1 WP_003853347.1 fig|1166015.3.peg.2283 592 599 yes 1890621 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 645 660 yes 1890622 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67348 Streptomyces prunicolor Bacteria 517884899 WP_019055107.1 591 612 yes 1890623 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169159 Streptomyces sp. CNY228 Bacteria 517724663 WP_018894871.1 595 597 yes 1890624 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 252305 Oceanicola batsensis HTCC2597 Bacteria UP000004318 84390003 EAQ02637.1 fig|252305.3.peg.2180 589 592 yes 1890625 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 849, 469615 Fusobacterium gonidiaformans, Fusobacterium gonidiaformans ATCC 25563 Bacteria UP000019281 498366046, 313691351 EFS28186.1 WP_010680202.1 433 433 yes 1890626 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 545533, 1129374 Alishewanella jeotgali, Alishewanella jeotgali KCTC 22429 Bacteria UP000012046 496235310, 374571381 EHR42509.1 WP_008949345.1 fig|1129374.4.peg.295 598 623 yes 1890627 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913063 Salmonella enterica subsp. enterica serovar Adelaide str. A4-669 Bacteria UP000004906 353562582 EHC29175.1 fig|913063.3.peg.4468 367 374 no 1890628 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280666 Butyrivibrio sp. AE3009 Bacteria 551035683 WP_022779500.1 434 434 yes 1890629 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39669, 679901 Methanosalsum zhilinae, Methanosalsum zhilinae DSM 4017 Archaea UP000006622 503663999, 336476714, 335930095 AEH60636.1 WP_013898075.1, YP_004615855.1 F7XKN0 F7XKN0_METZD 426 426 yes 1890630 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 69042 Synechococcus sp. WH 5701 Bacteria UP000002935 87283553 EAQ75508.1 161 165 no 1890631 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 807, 1094555, 1094554 Bartonella elizabethae, Bartonella elizabethae F9251, Bartonella elizabethae Re6043vi Bacteria UP000008941, UP000008942 492190092, 395430109, 395417624 EJF96160.1, EJF83961.1 WP_005773789.1 fig|1094554.3.peg.718, fig|1094555.3.peg.797 598 606 yes 1890632 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 559 559 yes 1890633 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1095699 Neisseria meningitidis, Neisseria meningitidis 98080 Bacteria UP000050419, UP000010750 488174049, 432200722 ELK56811.1 WP_002245257.1 fig|1095699.3.peg.2694 625 633 yes 1890634 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1404244, 1404245 Corynebacterium glycinophilum, Corynebacterium glycinophilum AJ 3170 Bacteria UP000023703 740761712, 610392520 AHW63483.1 WP_038546996.1 575 585 yes 1890635 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1292037 Amycolatopsis vancoresmycina DSM 44592 Bacteria UP000014139 486082244 EOD65254.1 fig|1292037.4.peg.5206 540 542 yes 1890636 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 759851, 1027292 Sporosarcina sp. 6062, Sporosarcina newyorkensis 2681 Bacteria UP000005316 497179052, 339621433 EGQ25992.1 WP_009498660.1 591 591 yes 1890637 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 225196 Geopsychrobacter electrodiphilus Bacteria 522166069 WP_020677277.1 433 435 yes 1890638 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053224, 1053203 Bacillus cereus, Bacillus cereus VD021, Bacillus cereus HuA2-4 Bacteria UP000036076, UP000014040, UP000007000 488072382, 500355385, 401157458 EOO73008.1, EJQ64856.1 WP_002143779.1 fig|1053224.3.peg.3942, fig|1053203.3.peg.5064 586 586 yes 1890639 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28182, 1001595 Leptospira noguchii, Leptospira noguchii serovar Panama str. CZ214 Bacteria UP000015442 515783126, 529331635 EQA72748.1 WP_017215585.1 442 496 yes 1890640 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 582514, 582515 Rubidibacter lacunae, Rubidibacter lacunae KORDI 51-2 Bacteria UP000016960 550281600, 549081598 ERN40888.1 WP_022607976.1 459 460 yes 1890641 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 549 550 yes 1890642 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 62320, 543526 Haloterrigena turkmenica, Haloterrigena turkmenica DSM 5511 Archaea UP000001903 502707324, 284164614, 284014269 ADB60220.1 WP_012942526.1, YP_003402893.1 D2RPW1 D2RPW1_HALTV 10311321 457 480 yes 1890643 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 188144 Enterovibrio norvegicus Bacteria 515572229 WP_017005025.1 643 643 yes 1890644 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 598467 Brenneria sp. EniD312 Bacteria UP000002759 496405941, 353677477 EHD23510.1 WP_009114805.1 630 649 yes 1890645 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630, 1194086 Yersinia enterocolitica, Yersinia enterocolitica subsp. enterocolitica WA-314 Bacteria UP000029427, UP000004718 491317711, 755285886, 685186300, 404511630 AJI83517.1, KGA73868.1, EKA25499.1 WP_005175678.1 fig|1194086.3.peg.3893 634 655 yes 1890646 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 95607 Rhodopseudomonas sp. B29 Bacteria 550972033 WP_022720247.1 636 646 yes 1890647 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 7213 Ceratitis capitata Invertebrates 498978876 XP_004528964.1 518 523 yes 1890648 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 574750 Cupriavidus sp. SK4 Bacteria UP000023556 737853354, 601444605 EYS91724.1 WP_035820575.1 624 626 yes 1890649 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 318425, 1440774 Mycobacterium aromaticivorans, Mycobacterium aromaticivorans JS19b1 Bacteria UP000022835 738391300, 635710753 KDF00447.1 WP_036343088.1 454 521 yes 1890650 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1969 Streptomyces chartreusis Bacteria 497718652 WP_010032836.1 592 594 yes 1890651 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1157635 Streptomyces sp. ATexAB-D23 Bacteria 517379668 WP_018553939.1 595 597 yes 1890652 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 545 547 yes 1890653 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1198114 Granulicella tundricola MP5ACTX9 Bacteria UP000000343 321162610 ADW68315.1 fig|696844.5.peg.1924 495 523 yes 1890654 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1085538 Leptospira interrogans serovar Bataviae str. HAI135 Bacteria UP000012139 464348883 EMO28274.1 222 298 no 1890655 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1085538 Leptospira interrogans serovar Bataviae str. HAI135 Bacteria UP000012139 464348886 EMO28277.1 111 111 no 1890656 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1078764 Corynebacterium sp. HFH0082 Bacteria UP000014413 512048150 EPD47818.1 fig|1078764.3.peg.1098 560 572 yes 1890657 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1298609 Psychrobacter sp. JCM 18901 Bacteria UP000019501 589896710 246 291 no 1890658 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 86959 Zymophilus raffinosivorans Bacteria 518383247 WP_019553454.1 433 435 yes 1890659 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263062 Butyrivibrio crossotus CAG:259 Environmental samples UP000018300 547223793, 524099361 WP_021960963.1 435 436 yes 1890660 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 403191, 1230453 Haloferax elongans, Haloferax elongans ATCC BAA-1513 Archaea 495601438, 445731035 ELZ82622.1 WP_008326017.1 M0HFW2 M0HFW2_9EURY 458 482 yes 1890661 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 154, 665571 Spirochaeta thermophila, Spirochaeta thermophila DSM 6192 Bacteria UP000001296 503078048, 306531585 ADN01119.1 WP_013312960.1 fig|665571.4.peg.145 423 424 yes 1890662 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1192034 Chondromyces apiculatus DSM 436 Bacteria UP000019678 599562050 EYF00431.1 545 576 yes 1890663 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 537937 Bifidobacterium longum, Bifidobacterium longum subsp. infantis CCUG 52486 Bacteria UP000028505, UP000005084 494112535, 239516407 EEQ56274.1 WP_007053315.1 fig|537937.5.peg.2068 635 917 yes 1890664 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 585366062 WP_024247646.1 626 631 yes 1890665 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281225, 1281223, 1281162, 1281060 Escherichia coli, Escherichia coli UMEA 3230-1, Escherichia coli UMEA 3221-1, Escherichia coli KOEGE 56 (169a), Escherichia coli HVH 125 (4-2634716) Bacteria UP000036210, UP000016373, UP000016028, UP000016317, UP000016283 545231302, 535704161, 535700986, 535421108, 534990731 EQY39147.1, EQY36044.1, EQV61938.1, EQR38961.1 WP_021530915.1 626 631 yes 1890666 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1330043, 1313, 1431339 Bacillus bombysepticus str. Wang, Streptococcus pneumoniae, Bacillus thuringiensis DB27 Bacteria UP000031778, UP000029709, UP000030682 662063656, 612492487, 814306268, 806775775, 589233388 AHX21155.1 WP_030029377.1 586 586 yes 1890667 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 225196 Geopsychrobacter electrodiphilus Bacteria 522164138 WP_020675346.1 433 433 yes 1890668 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 877455 Methanobacterium sp. 17A1 Archaea UP000007490 503411370, 325331618 ADZ10680.1 WP_013646031.1 F0T746 F0T746_METLA 424 424 yes 1890669 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263031 Firmicutes bacterium CAG:56 Environmental samples UP000018123 547617584, 524305869 WP_022117941.1 435 436 yes 1890670 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 440 441 yes 1890671 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1300253 Alteromonas macleodii str. 'English Channel 615' Bacteria UP000014909 521321490 AGP76553.1 602 602 yes 1890672 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1010838 Mycobacterium avium subsp. paratuberculosis S397 Bacteria UP000004813 336460346 EGO39246.1 fig|1078005.3.peg.3590, fig|262316.1.peg.3913, fig|1078003.3.peg.4298, fig|1029814.3.peg.1689, fig|1078002.3.peg.92, fig|1078004.3.peg.4309, fig|1029813.3.peg.4021, fig|1199187.3.peg.4155, fig|1029821.3.peg.4056, fig|1010838.3.peg.1675, fig|1029818.3.peg.1792 531 532 yes 1890673 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 816, 1339348, 1339349, 1235787, 457393, 1263055 Bacteroides uniformis str. 3978 T3 i, Bacteroides uniformis str. 3978 T3 ii, Bacteroides uniformis dnLKV2, Bacteroides sp. 4_1_36, Bacteroides uniformis CAG:3 Bacteria, Environmental samples UP000028100, UP000028013, UP000014212, UP000004735, UP000018282 495940029, 649553861, 649541745, 507748032, 316903713, 524693126 KDS60409.1, KDS48625.1, EOS07049.1, EFV25557.1 WP_008664608.1 fig|1235787.3.peg.2870, fig|457393.3.peg.2507 560 560 yes 1890674 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543, 575, 1005996, 54291 Raoultella planticola, Raoultella planticola ATCC 33531, Raoultella ornithinolytica Bacteria UP000030492, UP000028648, UP000056624 695766974, 721572973, 669000438, 619494363 KGZ16273.1, KFD11960.1, KAJ94112.1 WP_032689994.1 626 631 yes 1890675 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47951 Vibrio cyclitrophicus Bacteria 515169461 WP_016797956.1 640 649 yes 1890676 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 1357398 Fusobacterium nucleatum, Fusobacterium nucleatum 13_3C Bacteria UP000022236 696314732, 576330905 ETZ25555.1 WP_032890154.1 433 433 yes 1890677 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1412530 Salmonella enterica subsp. enterica serovar Enteritidis str. EC20121004 Bacteria UP000062657 603584261 AHS51885.1 229 229 no 1890678 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 803, 1134501, 1134502, 1134503, 1134504, 1134505, 1134506, 1134507, 1402975, 1402974, 1402976, 1402977, 1402978, 283165 Bartonella quintana, Bartonella quintana JK 39, Bartonella quintana JK 67, Bartonella quintana JK 68, Bartonella quintana JK 56, Bartonella quintana JK 63, Bartonella quintana JK 31, Bartonella quintana JK 19, Bartonella quintana JK 12, Bartonella quintana JK 7, Bartonella quintana JK 73, Bartonella quintana JK 73rel, Bartonella quintana BQ2-D70, Bartonella quintana str. Toulouse Bacteria UP000027184, UP000027350, UP000027143, UP000027226, UP000027183, UP000027248, UP000027292, UP000018929, UP000018920, UP000018945, UP000018978, UP000018935, UP000000597 499492559, 654338880, 654338505, 654337555, 654334967, 654332387, 654331023, 654330443, 572296395, 572295563, 572293479, 572291739, 572288858, 81647158, 49239553 KEC68172.1, KEC67801.1, KEC66857.1, KEC64360.1, KEC61828.1, KEC60509.1, KEC59992.1, ETS19018.1, ETS18189.1, ETS16187.1, ETS14501.1, ETS11694.1 WP_011179199.1 Q6G099 THIC_BARQU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 602533 fig|283165.1.peg.361 583 588 yes 1890679 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44674, 760154 Sulfurospirillum barnesii, Sulfurospirillum barnesii SES-3 Bacteria UP000006176 504581689, 390192856 AFL67911.1 WP_014768791.1 fig|760154.4.peg.599 621 622 yes 1890680 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305, 1091042 Ralstonia solanacearum, Ralstonia solanacearum K60-1 Bacteria UP000029286, UP000003425 489365439, 378963558 WP_003272291.1 fig|1091042.3.peg.2937 629 631 yes 1890681 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 222984, 1227494 Natrinema altunense, Natrinema altunense JCM 12890 Archaea 494168032, 445638275 ELY91412.1 WP_007107761.1 M0A0Q2 M0A0Q2_9EURY 457 481 yes 1890682 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1310660, 1310621, 981334 Acinetobacter baumannii 983759, Acinetobacter baumannii 869535, Acinetobacter radioresistens DSM 6976 Bacteria UP000023786, UP000023794, UP000018429 491164616, 588137782, 587947911, 480051655, 403187746 EXE13537.1, EXC34185.1, ENV90755.1 WP_005022988.1 fig|981334.3.peg.610, fig|1221310.3.peg.434 626 630 yes 1890683 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 159449 Streptomyces scabrisporus Bacteria 522045984 WP_020557193.1 581 593 yes 1890684 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1131266 Marine Group I thaumarchaeote SCGC AB-629-I23 Archaea 519092422 WP_020248297.1 442 442 yes 1890685 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 391036 Ehrlichia sp. HF Bacteria UP000023762 763336808, 612494498 AHX04341.1 WP_044195137.1 553 553 yes 1890686 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158291 Thiomonas sp. FB-6 Bacteria 517743020 WP_018913228.1 627 628 yes 1890687 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1355388 Elizabethkingia meningoseptica 502 Bacteria UP000015692 530697663 EQB92141.1 575 575 yes 1890688 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43080 Sulfolobus islandicus Archaea 515102543 WP_016731721.1 432 433 yes 1890689 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1339284 Bacteroides fragilis str. 3397 T10 Bacteria UP000022725 595924038 EXY33648.1 307 307 yes 1890690 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913080 Salmonella enterica subsp. enterica serovar Mississippi str. A4-633 Bacteria UP000003218 353612671 EHC64988.1 fig|913080.3.peg.4407 147 148 no 1890691 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 420950, 1094980 Methanolobus psychrophilus, Methanolobus psychrophilus R15 Archaea UP000000459 504866628, 409170146 AFV24021.1 WP_015053730.1 K4MPX7 K4MPX7_9EURY 406 415 no 1890692 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 58138, 485916 Desulfotomaculum acetoxidans, Desulfotomaculum acetoxidans DSM 771 Bacteria UP000002217 506237477, 257778647 ACV62541.1 WP_015757252.1 fig|485916.4.peg.4102 430 431 yes 1890693 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 992011 Vibrio sp. HENC-02 Bacteria UP000008367 408890870 EKM28857.1 fig|992011.3.peg.3341 640 646 yes 1890694 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1279027 Hippea alviniae Bacteria 550921413 WP_022669933.1 427 428 yes 1890695 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 516018956 WP_017449539.1 640 646 yes 1890696 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 983548 Krokinobacter sp. 4H-3-7-5 Bacteria UP000008290 503517696, 332171375 AEE20630.1 WP_013752137.1 fig|983548.3.peg.2736 619 619 yes 1890697 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 396513 Staphylococcus carnosus subsp. carnosus TM300 Bacteria UP000000444 222420694 fig|396513.4.peg.598 427 467 no 1890698 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28031, 1231627, 714961 Lysinibacillus fusiformis, Lysinibacillus fusiformis ZB2, Lysinibacillus fusiformis ZC1 Bacteria UP000029429, UP000009389, UP000004048 490354038, 422947168, 298725422 EKU41567.1, EFI66067.1 WP_004233811.1 fig|714961.3.peg.4535, fig|1231627.3.peg.3518 592 592 yes 1890699 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 396513 Staphylococcus carnosus subsp. carnosus TM300 Bacteria UP000000444 222420695 fig|396513.4.peg.599 136 136 no 1890700 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 125627 Thiothrix flexilis Bacteria 522048724 WP_020559933.1 586 587 yes 1890701 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263550, 1578828 Edwardsiella piscicida, Edwardsiella sp. EA181011 Bacteria UP000027363, UP000035881 779991662, 834904226, 635158810 AKM46257.1 WP_045428271.1 627 643 yes 1890702 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1068978 Amycolatopsis methanolica 239 Bacteria UP000062973 672360659 AIJ26537.1 544 547 yes 1890703 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 749532, 749545 Escherichia coli, Escherichia coli MS 78-1, Escherichia coli MS 182-1 Bacteria UP000036210, UP000004107, UP000003134 447199669, 300847491, 300418053 EFK75251.1, EFK01364.1 WP_001276925.1 626 631 yes 1890704 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 752786 Escherichia coli, Escherichia coli 541-1 Bacteria UP000036210, UP000003243 447199668, 388409212 EIL69531.1 WP_001276924.1 fig|752786.3.peg.18 626 631 yes 1890705 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446581, 1117111, 1097579, 1105330, 1281080, 1116047, 869686 Escherichia coli, Escherichia coli O128:H2 str. 2011C-3317, Escherichia coli P4-NR, Escherichia coli P4-96, Escherichia coli TW07509, Escherichia coli HVH 147 (4-5893887), Escherichia coli P0299917.1, Escherichia coli 9.0111 Bacteria UP000036210, UP000027742, UP000017911, UP000018257, UP000016024, UP000016107, UP000012365, UP000005347 447199667, 748029632, 729843293, 729827531, 651680351, 558713099, 558711342, 536870069, 535082386, 476698087, 386214983 KIG41220.1, KHH37156.1, KHH21735.1, KDV62529.1, EST64385.1, EST62653.1, ERC52420.1, EQS28904.1, ENA03276.1, EII25387.1 WP_001276923.1 fig|869686.3.peg.4563, fig|1116047.3.peg.4200 626 631 yes 1890706 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444231, 1337384, 752785 Escherichia coli, Escherichia coli 2-156-04_S4_C2, Escherichia coli SCD1, Escherichia coli 541-15 Bacteria UP000036210, UP000027673, UP000017568, UP000004544 447199666, 652003641, 553018106, 388394120 KDX23589.1, ESA25059.1, EIL55435.1 WP_001276922.1 fig|752785.3.peg.1937 626 631 yes 1890707 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 447199665 WP_001276921.1 626 631 yes 1890708 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 623, 766153, 766145 Shigella flexneri, Shigella flexneri K-1770, Shigella flexneri VA-6 Bacteria UP000029282, UP000005352, UP000004258 447199663, 391247136, 333010727 EIQ06390.1, EGK30155.1 WP_001276919.1 fig|766153.3.peg.4260, fig|766145.3.peg.36 626 631 yes 1890709 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 623, 766147, 766148 Shigella flexneri, Shigella flexneri K-227, Shigella flexneri K-272 Bacteria UP000029282, UP000004520, UP000004461 447199662, 333014318, 332998858 EGK33672.1, EGK18453.1 WP_001276918.1 fig|766147.3.peg.4017, fig|766148.3.peg.4195 626 631 yes 1890710 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 623, 766161, 766146, 766160 Shigella flexneri, Shigella flexneri 6603-63, Shigella flexneri K-218, Shigella flexneri 4343-70 Bacteria UP000029282, UP000007298, UP000005465, UP000004607 447199661, 684117742, 397902421, 332998961, 332751452 KFZ99244.1, EJL18740.1, EGK18551.1, EGJ81854.1 WP_001276917.1 fig|766161.3.peg.16, fig|766146.3.peg.4529, fig|766160.3.peg.3725 626 631 yes 1890711 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1069495 Escherichia coli, Escherichia coli XH001 Bacteria UP000036210, UP000004812 447199660, 344191690 EGV45800.1 WP_001276916.1 fig|1069495.4.peg.4064 626 631 yes 1890712 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 135735 Bacillus endophyticus Bacteria UP000036202 518224518 WP_019394726.1 589 589 yes 1890713 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 913028 Yersinia enterocolitica W22703 Bacteria 330863068 634 657 yes 1890714 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1069, 648757 Rhodomicrobium vannielii, Rhodomicrobium vannielii ATCC 17100 Bacteria UP000001399 503185371, 311220282 ADP71650.1 WP_013420032.1 fig|648757.3.peg.538 612 618 yes 1890715 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305, 1431453, 1031711 Ralstonia solanacearum, Ralstonia solanacearum P673, Ralstonia solanacearum Po82 Bacteria UP000029286, UP000021416, UP000007953 504431143, 577751661, 334197359 EUJ13508.1, AEG70544.1 WP_014618245.1 fig|1031711.3.peg.3184 629 631 yes 1890716 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 512030 Acidovorax sp. NO-1 Bacteria UP000003485 496179209, 363416827 EHL23923.1 WP_008903716.1 fig|512030.4.peg.964 623 631 yes 1890717 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68911, 1227492 Natrialba chahannaoensis, Natrialba chahannaoensis JCM 10990 Archaea 493162809, 445641266 ELY94348.1 WP_006169249.1 M0AAH4 M0AAH4_9EURY 473 488 yes 1890718 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 95486, 1396830 Burkholderia cenocepacia, Burkholderia cenocepacia KC-01 Bacteria UP000065887, UP000032887 558019299, 557792863 ESS36956.1 WP_023477848.1 642 643 yes 1890719 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 517342256 WP_018517748.1 599 605 yes 1890720 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 992012 Vibrio sp. HENC-03 Bacteria UP000008371 497390980, 408887889 EKM26379.1 WP_009705193.1 fig|992012.3.peg.1360 640 646 yes 1890721 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1198452 Janthinobacterium sp. HH01 Bacteria UP000011616 495720611, 444791060 ELX12607.1 WP_008445190.1 fig|1198452.4.peg.1206 637 638 yes 1890722 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 655338, 1403537 Clostridiaceae bacterium AeB, Fervidicella metallireducens AeB Bacteria UP000019681 737397921, 599129820 EYE88663.1 WP_035379320.1 437 437 yes 1890723 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 49186 Marinobacterium stanieri Bacteria 498010346 WP_010324502.1 628 629 yes 1890724 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1496, 1151413, 1151421, 1151407, 1151367, 1215071 Clostridium difficile, Clostridium difficile P31, Clostridium difficile P45, Clostridium difficile P23, Clostridium difficile F253, Clostridium difficile E19 Bacteria UP000058232, UP000015829, UP000015774, UP000015719, UP000015817, UP000018286 497578362, 531817489, 531708767, 531668302, 531530979, 549331257 EQK92018.1, EQJ85812.1, EQJ45917.1, EQI15040.1 WP_009892546.1 339 366 no 1890725 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913072 Salmonella enterica subsp. enterica serovar Give str. S5-487 Bacteria UP000006003 353582572 EHC43190.1 fig|913072.3.peg.4425 181 204 no 1890726 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 507750, 862517 Peptoniphilus duerdenii, Peptoniphilus duerdenii ATCC BAA-1640 Bacteria UP000003280 496176957, 304372173 EFM25767.1 WP_008901464.1 436 438 yes 1890727 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40567, 446462 Actinosynnema mirum, Actinosynnema mirum DSM 43827 Bacteria UP000002213 502426160, 255918881 ACU34392.1 WP_012783055.1 fig|446462.6.peg.433 541 547 yes 1890728 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1124962 Salmonella enterica, Salmonella enterica subsp. enterica serovar Poona str. ATCC BAA-1673 Bacteria UP000054489, UP000017517 555220935, 554175262 ESG14576.1 WP_023213640.1 626 631 yes 1890729 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 206672, 216816, 1300227, 1679, 1457186, 1457185, 1350473, 1298922, 205913, 1205679, 77133, 565042, 722911 Bifidobacterium longum NCC2705, Bifidobacterium longum, Bifidobacterium longum subsp. longum GT15, Bifidobacterium longum subsp. longum, Bifidobacterium longum subsp. longum EK13, Bifidobacterium longum subsp. longum EK5, Bifidobacterium longum subsp. longum 17-1B, Bifidobacterium longum D2957, Bifidobacterium longum DJO10A, Bifidobacterium longum subsp. longum CECT 7347, uncultured bacterium, Bifidobacterium longum subsp. longum JCM 1217, Bifidobacterium longum subsp. longum F8 Bacteria, Environmental samples UP000000439, UP000028505, UP000030089, UP000029007, UP000028299, UP000028314, UP000028233, UP000017045, UP000002419, UP000018160, UP000041370, UP000007255, UP000007063 23464740, 499380394, 703668679, 672966816, 665781482, 665778456, 665771884, 512436695, 189427430, 23325309, 540723281, 530777013, 320456377, 291516130, 47606179 AIW43995.1, KFI62294.1, KEY31218.1, KEY28241.1, KEY21773.1, EPE38317.1, ACD97578.1, AAN23979.1 NP_695343.1, WP_011067965.1 Q8G7X1 THIEC_BIFLO Thiamine biosynthesis bifunctional protein ThiEC 6143960, 280393, 7771834 fig|206672.1.peg.112, fig|722911.3.peg.28, fig|565042.3.peg.1382, fig|205913.6.peg.149 635 917 yes 1890730 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1299323 Mycobacterium abscessus 1948 Bacteria UP000021210 576469321 EUA62915.1 148 148 no 1890731 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1299323 Mycobacterium abscessus 1948 Bacteria UP000021210 576469320 EUA62914.1 341 370 no 1890732 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39669, 679901 Methanosalsum zhilinae, Methanosalsum zhilinae DSM 4017 Archaea UP000006622 503665185, 336477904, 335931285 AEH61826.1 WP_013899261.1, YP_004617045.1 F7XMF3 F7XMF3_METZD 419 426 yes 1890733 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 246167 Vibrio crassostreae Bacteria UP000049932 515636998 WP_017069598.1 640 649 yes 1890734 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446702, 1169378, 1181742 Escherichia coli, Escherichia coli O169:H41 str. F9792, Escherichia coli KTE117, Escherichia coli KTE196 Bacteria UP000036210, UP000024121, UP000010704, UP000010496 486419522, 607432582, 431551580, 431466299 EZB23159.1, ELI25565.1, ELH46375.1 WP_001612144.1 fig|1181742.3.peg.232, fig|1169378.3.peg.4133 626 631 yes 1890735 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 712401, 1127694 Neisseria sp. oral taxon 020, Neisseria sp. oral taxon 020 str. F0370 Bacteria UP000010457 496985899, 429160242 EKY02717.1 WP_009427641.1 fig|1127694.3.peg.2634 622 626 yes 1890736 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28442, 662477 Haloarcula vallismortis, Haloarcula vallismortis ATCC 29715 Archaea 490650503, 445759047 EMA10334.1 WP_004515497.1 M0JQR5 M0JQR5_HALVA 455 480 yes 1890737 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053195 Bacillus cereus, Bacillus cereus BAG6X1-2 Bacteria UP000036076, UP000006986 488052542, 401137776 EJQ45354.1 WP_002123939.1 fig|1053195.3.peg.4664 586 586 yes 1890738 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913086 Salmonella enterica subsp. enterica serovar Wandsworth str. A4-580 Bacteria UP000003536 353665419 EHD03552.1 181 193 no 1890739 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47877, 629259 Pseudomonas amygdali, Pseudomonas syringae pv. morsprunorum str. M302280PT Bacteria UP000050412, UP000004549 492063675, 330873824 EGH07973.1 WP_005736887.1 627 629 yes 1890740 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 364410, 1052095 Granulibacter bethesdensis, Granulibacter bethesdensis CGDNIH4 Bacteria UP000019437 644464178, 586602715 AHJ64475.1 WP_025319411.1 603 610 yes 1890741 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314253 Nitrobacter sp. Nb-311A Bacteria UP000003725 497484525, 85697181 EAQ35062.1 WP_009798723.1 fig|314253.3.peg.2289 636 646 yes 1890742 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644283 Micromonospora aurantiaca ATCC 27029 Bacteria UP000001908 302572786 ADL48988.1 fig|644283.3.peg.3283 530 530 yes 1890743 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 140626 Lachnobacterium bovis Bacteria 551004081 WP_022748781.1 438 441 yes 1890744 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1125974 Thermoanaerobacter indiensis Bacteria 518749702 WP_019907952.1 431 432 yes 1890745 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 859657 Ralstonia solanacearum PSI07 Bacteria UP000006858 299079943 fig|859657.5.peg.4897 629 631 yes 1890746 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 199, 1242966 Campylobacter concisus, Campylobacter concisus UNSW3 Bacteria UP000066049, UP000016636 544650217, 543203449 ERJ22767.1 WP_021084238.1 431 431 yes 1890747 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1510466, 1229908 Candidatus Nitrosopumilus koreensis, Candidatus Nitrosopumilus koreensis AR1 Archaea UP000006101 504775744, 407462082, 407045704 AFS80457.1 WP_014962846.1, YP_006773399.1 K0B5T1 K0B5T1_9ARCH 451 453 yes 1890748 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 710111 Frankia sp. QA3 Bacteria UP000003979 392288362 EIV94386.1 577 596 yes 1890749 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144336 Pseudomonas sp. GM74 Bacteria UP000007290 495323263, 398207517 EJM94266.1 WP_008048009.1 fig|1144336.3.peg.1371 628 629 yes 1890750 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 125216 518291774 WP_019461982.1 601 609 yes 1890751 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 92938 Fischerella muscicola Bacteria 515358618 WP_016866611.1 458 459 yes 1890752 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1390, 1449088 Bacillus amyloliquefaciens, Bacillus amyloliquefaciens subsp. plantarum TrigoCor1448 Bacteria UP000027101, UP000019448 644172776, 589091698 AHK48450.1 WP_025284452.1 590 590 yes 1890753 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1391999 Mycobacterium avium 10-5560 Bacteria UP000018600 564215852 ETB48272.1 464 465 yes 1890754 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262909 Odoribacter sp. CAG:788 Environmental samples UP000018100 547252914, 524132974 WP_021988491.1 579 582 yes 1890755 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1639108, 1441930 Serratia multitudinisentens, Serratia fonticola RB-25 Bacteria UP000019030 640473606, 573929238 AHG20535.1 WP_024914158.1 fig|369723.3.peg.1319 633 647 yes 1890756 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262774 Clostridium sp. CAG:127 Environmental samples UP000018025 547249844, 524130750 WP_021985482.1 433 434 yes 1890757 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37636, 743525 Thermus scotoductus, Thermus scotoductus SA-01 Bacteria UP000053099, UP000008087 505921468, 320150426 ADW21804.1 WP_015717081.1 fig|743525.8.peg.1145 437 443 yes 1890758 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262776 Clostridium sp. CAG:149 Environmental samples UP000017912 547229942, 524106559 WP_021966755.1 447 449 yes 1890759 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1453999 Candidatus Accumulibacter sp. SK-02 Bacteria UP000021315 736950594, 668685076 KFB77373.1 WP_034947430.1 638 638 yes 1890760 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1001586 Leptospira interrogans serovar Bulgarica str. Mallika Bacteria UP000006609 400351621 EJP03840.1 227 227 no 1890761 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1331277 Bordetella pertussis STO1-CHOC-0017 Bacteria UP000018678 565776852 ETH84925.1 636 1134 yes 1890762 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 530 530 yes 1890763 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33952, 931626 Acetobacterium woodii, Acetobacterium woodii DSM 1030 Bacteria UP000007177 504120605, 375300853 AFA46987.1 WP_014354591.1 fig|931626.3.peg.188 435 437 yes 1890764 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1241935 Sulfolobus islandicus LAL14/1 Archaea UP000013006 478753655 AGJ62227.1 M9U7W4 M9U7W4_SULIS 171 172 no 1890765 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34305 Lotus japonicus Plants 388501574 AFK38853.1 420 435 yes 1890766 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28034 Sulfobacillus thermosulfidooxidans Bacteria 521043525 WP_020375549.1 581 581 yes 1890767 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83455, 1278073 Myxococcus stipitatus, Myxococcus stipitatus DSM 14675 Bacteria UP000011131 505162179, 441488326 AGC45021.1 WP_015349281.1 fig|1278073.3.peg.3778 621 624 yes 1890768 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 438 Acetobacter pasteurianus Bacteria UP000037575 517918415 WP_019088623.1 606 626 yes 1890769 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 332056, 1301087 Sphingobium japonicum, Sphingobium japonicum BiD32 Bacteria UP000013201 494016427, 482643438 WP_006958770.1 fig|1301087.3.peg.2724 655 663 yes 1890770 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310815, 1310826, 1310673, 1310668, 1310625, 1310648, 1310733, 1310783, 1310798, 1310782, 1310740, 1310719, 1310721, 1310813, 1310686, 1310653, 1096996, 903910, 903913 Acinetobacter baumannii, Acinetobacter baumannii 756476, Acinetobacter baumannii 1195185_80, Acinetobacter baumannii 1499986, Acinetobacter baumannii 754286, Acinetobacter baumannii 496487, Acinetobacter baumannii 110912, Acinetobacter baumannii 1195185_11, Acinetobacter baumannii 214216, Acinetobacter baumannii 14216, Acinetobacter baumannii 1170863, Acinetobacter baumannii 457946, Acinetobacter baumannii 607805, Acinetobacter baumannii 1533268, Acinetobacter baumannii 722310, Acinetobacter baumannii 397971, Acinetobacter baumannii 951631, Acinetobacter baumannii BJAB0715, Acinetobacter baumannii OIFC110, Acinetobacter baumannii WC-692 Bacteria UP000028632, UP000027139, UP000027324, UP000027309, UP000027155, UP000027233, UP000023028, UP000021450, UP000023176, UP000021702, UP000022297, UP000020441, UP000020694, UP000021982, UP000022514, UP000022137, UP000020632, UP000014804, UP000007837, UP000006084 446995598, 672212783, 656771646, 656770214, 630572443, 630519091, 630492750, 630467174, 630442962, 602205573, 602202343, 593601006, 593587901, 593504507, 589520661, 589520575, 589471987, 589164524, 588192989, 587953878, 522368682, 408714777, 404563645 KFG11580.1, KEF50211.1, KEF48806.1, KCY77136.1, KCY26911.1, KCY02637.1, KCX79898.1, KCX58295.1, EYT34593.1, EYT31394.1, EXR82828.1, EXR70252.1, EXQ90104.1, EXI00846.1, EXI00761.1, EXH53673.1, EXG10209.1, EXE66415.1, EXC39588.1, AGQ04945.1, EKL59910.1, EKA68846.1 WP_001072854.1 fig|903913.3.peg.2503, fig|903910.3.peg.1362 621 625 yes 1890771 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1800, 710421 Mycobacterium chubuense, Mycobacterium chubuense NBB4 Bacteria UP000036176, UP000006057 504618441, 390619105 AFM20254.1 WP_014805543.1 fig|710421.3.peg.5579 526 533 yes 1890772 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901 Salmonella enterica Bacteria UP000054489 583091250 WP_024155698.1 626 631 yes 1890773 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1009852 Comamonas testosteroni ATCC 11996 Bacteria UP000003186 371451266 EHN64307.1 fig|1009852.3.peg.3720 625 654 yes 1890774 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 619 619 yes 1890775 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42235, 1054862 Streptomyces bottropensis, Streptomyces bottropensis ATCC 25435 Bacteria UP000030760 491625369, 456387059 EMF52572.1 WP_005482909.1 595 614 yes 1890776 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1414836 Xanthomonas arboricola pv. pruni str. MAFF 311562 Bacteria UP000019143 575385590 478 478 no 1890777 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1390, 1457158 Bacillus amyloliquefaciens, Bacillus amyloliquefaciens EBL11 Bacteria UP000027101, UP000020942 696292602, 597504137 EYB34760.1 WP_032868244.1 590 590 yes 1890778 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1190575 Neisseria meningitidis, Neisseria meningitidis NM003 Bacteria UP000050419, UP000015677 545066913, 530909831 EQD07938.1 WP_021438804.1 625 633 yes 1890779 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262740 Bacteroides sp. CAG:462 Environmental samples UP000018063 548163259, 524669334 WP_022386079.1 566 566 yes 1890780 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469585 Bacteroides sp. 1_1_14 Bacteria UP000003951 496036817, 298261564 EFI04430.1 WP_008761324.1 527 529 yes 1890781 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 15368 Brachypodium distachyon Plants UP000008810 UP000008810 357119153 XP_003561310.1 549 643 yes 1890782 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1502, 742739 Clostridium perfringens, Clostridium perfringens WAL-14572 Bacteria UP000059070, UP000003745 489572518, 373227842 EHP50152.1 WP_003476964.1 fig|742739.3.peg.103 436 436 yes 1890783 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1461766 Pseudoalteromonas sp. SCSIO_11900 Bacteria UP000023530 739111471, 586921440 EWS98514.1 WP_036981185.1 645 650 yes 1890784 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423, 1453990, 1302650 Bacillus subtilis, Bacillus subtilis HJ5, Bacillus subtilis subsp. subtilis str. BAB-1 Bacteria UP000030083, UP000033029, UP000012069 505295881, 808339417, 472253614 AKD34275.1, AGI28145.1 WP_015482983.1 fig|1302650.3.peg.901, fig|1233100.3.peg.970 590 590 yes 1890785 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 164330, 1234381 Thauera aminoaromatica, Thauera aminoaromatica S2 Bacteria UP000013042 490455381, 479289952 ENO78052.1 WP_004326186.1 639 639 yes 1890786 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 656024 Frankia symbiont of Datisca glomerata Bacteria UP000001549 503638702, 334858330 AEH08804.1 WP_013872778.1 569 614 yes 1890787 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 557 571 yes 1890788 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28172, 675813 Vibrio metschnikovii, Vibrio metschnikovii CIP 69.14 Bacteria UP000005604 490528616, 260613346 EEX38545.1 WP_004393824.1 640 644 yes 1890789 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1124 Chlorogloeopsis fritschii Bacteria 515385089 WP_016877430.1 455 457 yes 1890790 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 758829 Escherichia coli, Escherichia coli ECA-0157 Bacteria UP000036210, UP000018331 559164368, 558741310 EST88911.1 WP_023563232.1 626 631 yes 1890791 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1234606 Gayadomonas joobiniege Bacteria 516014052 WP_017444635.1 636 637 yes 1890792 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1385985, 1346330 Sphingobacterium paucimobilis, Sphingobacterium paucimobilis HER1398 Bacteria UP000016584 544635851, 543401285 ERJ58064.1 WP_021071544.1 607 607 yes 1890793 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1437444 Hydrogenophaga sp. T4 Bacteria UP000019362 586633083 EWS63740.1 439 445 yes 1890794 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1157640 Streptomyces sp. FxanaC1 Bacteria 516770274 WP_018092155.1 592 595 yes 1890795 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1403540 Halomonas sp. BCO4 Bacteria UP000019279 759821858, 584381595 EWG98692.1 WP_043517830.1 629 629 yes 1890796 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 658656 Lachnospiraceae bacterium 6_1_37FAA Bacteria UP000006471 496264097, 325470278 EGC73510.1 WP_008977482.1 434 435 yes 1890797 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 69527, 1227495 Natrinema pallidum, Natrinema pallidum DSM 3751 Archaea 493196153, 445621263 ELY74739.1 WP_006186316.1 L9YKS7 L9YKS7_9EURY 457 481 yes 1890798 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 520141 Mycobacterium tuberculosis T85 Bacteria UP000025335 289712060 EFD76072.1 276 277 no 1890799 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1605895, 424182 Rhizobium sp. LMB-1, Rhizobium sp. IRBG74 Bacteria UP000016944 549789959, 549127077 WP_022556897.1 599 607 yes 1890800 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1470558 Cupriavidus sp. SK-3 Bacteria UP000023560 737902109, 645569211 KDP85774.1 WP_035868410.1 625 628 yes 1890801 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 1400186 Serratia marcescens, Serratia marcescens BIDMC 44 Bacteria UP000055021, UP000022574 727166662, 575542316 ETX42747.1 WP_033636733.1 632 647 yes 1890802 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 398626, 1357400 Helicobacter macacae, Helicobacter macacae MIT 99-5501 Bacteria UP000018731 565845640, 564722130 ETD22163.1 WP_023928717.1 458 458 yes 1890803 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 525258, 525259 Clostridium difficile NAP07, Clostridium difficile NAP08 Bacteria UP000003072, UP000003227 296429999, 296259429 EFH15848.1, EFH06293.1 455 457 yes 1890804 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144341 Pantoea sp. YR343 Bacteria UP000007506 495383703, 398207213 EJM93966.1 WP_008108410.1 fig|1144341.3.peg.3449 631 640 yes 1890805 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 996 Flavobacterium columnare Bacteria UP000058566 117583101 ABK41833.1 250 251 no 1890806 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 136845, 1299319 Pseudomonas putida LF54 Bacteria UP000017057 545907308, 544277897 ERL00515.1 WP_021783856.1 625 626 yes 1890807 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1128427 filamentous cyanobacterium ESFC-1 Bacteria 517210682 WP_018399500.1 459 460 yes 1890808 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 46541, 391009 Thermosipho melanesiensis, Thermosipho melanesiensis BI429 Bacteria UP000001110 501004852, 149793988 ABR31436.1 WP_012057795.1 fig|391009.4.peg.1643 420 425 no 1890809 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 3343 Pinus lambertiana Plants 361068421 AEW08522.1 87 87 no 1890810 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 1334564 Serratia marcescens, Serratia marcescens SM39 Bacteria UP000055021, UP000031665 751568242, 573012795 WP_041037140.1 632 647 yes 1890811 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 330, 1453503 Pseudomonas pseudoalcaligenes, Pseudomonas mendocina AD6 Bacteria UP000033611, UP000023842 739138506, 610708929 EZH78444.1 WP_037003423.1 628 631 yes 1890812 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 203523 Longispora albida Bacteria 517158987 WP_018347805.1 534 537 yes 1890813 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1131283 zeta proteobacterium SCGC AB-133-C04 Bacteria 517097127 WP_018285945.1 622 622 yes 1890814 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1040988 Mesorhizobium sp. WSM4349 Bacteria 517265335 WP_018454153.1 623 632 yes 1890815 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 748247 Azoarcus sp. KH32C Bacteria UP000007106 505250291, 358638794 WP_015437393.1 fig|748247.4.peg.3770 638 638 yes 1890816 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463164 Klebsiella sp. 07A044 Bacteria UP000019761 591278980 626 687 yes 1890817 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310772, 1310683 Acinetobacter baumannii, Acinetobacter baumannii 1130196, Acinetobacter baumannii 1566109 Bacteria UP000028632, UP000020533, UP000023341 691023337, 593534493, 588205848 EXR18935.1, EXE78758.1 WP_031982167.1 621 625 yes 1890818 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 130048, 1227454 Halobiforma nitratireducens, Halobiforma nitratireducens JCM 10879 Archaea 493722414, 445791613 EMA42251.1 WP_006671835.1 M0M928 M0M928_9EURY 455 494 yes 1890819 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 28901, 1029986 Salmonella enterica, Salmonella enterica subsp. enterica serovar Enteritidis str. 50-5646 Bacteria UP000054489, UP000010956 487610050, 435311476 ELO85615.1 WP_001734379.1 366 369 no 1890820 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1402519 Pseudomonas aeruginosa, Pseudomonas aeruginosa BWHPSA019 Bacteria UP000065817, UP000017370 553785391, 552374511 ERW33221.1 WP_023116792.1 627 627 yes 1890821 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29466, 686660 Veillonella parvula, Veillonella parvula ATCC 17745 Bacteria UP000054707, UP000004102 490833553, 282580170 EFB85572.1 WP_004695637.1 434 434 yes 1890822 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 860, 620833 Fusobacterium periodonticum, Fusobacterium periodonticum D10 Bacteria UP000005809 492803554, 404590439 EKA92842.1 WP_005968740.1 fig|620833.3.peg.1843 433 433 yes 1890823 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204669 Candidatus Koribacter versatilis Ellin345 Bacteria UP000002432 94551384 ABF41308.1 fig|204669.6.peg.2291 483 489 yes 1890824 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 518634 Bifidobacterium breve, Bifidobacterium breve DSM 20213 Bacteria UP000029049, UP000035069 489927017, 672955412, 291381340, 781875815 KFI51031.1, EFE88858.1 WP_003830353.1 fig|518634.5.peg.504 635 917 yes 1890825 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 133924, 999552 Leisingera methylohalidivorans, Leisingera methylohalidivorans DSM 14336 Bacteria UP000018780 568322233, 568225518 AHD01440.1 WP_024090786.1 601 608 yes 1890826 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1509, 1075091 Clostridium sporogenes, Clostridium sporogenes PA 3679 Bacteria UP000051171, UP000005747 489592208, 365977048 EHN13151.1 WP_003496652.1 437 437 yes 1890827 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 50340 Pseudomonas fuscovaginae Bacteria UP000037883 518192644 WP_019362852.1 627 629 yes 1890828 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 518, 1331217 Bordetella bronchiseptica, Bordetella bronchiseptica M435/02/3 Bacteria UP000064190, UP000027235 704418031, 633455051 KDC38071.1 WP_033469488.1 636 637 yes 1890829 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 1421017, 1927, 1265868 Streptomyces rimosus R6-500, Streptomyces rimosus, Streptomyces rimosus subsp. rimosus ATCC 10970 Bacteria UP000027715, UP000028432, UP000011074 490076770, 655930432, 655923149, 440622570 KEF15178.1, KEF08104.1, ELQ85349.1 WP_003978930.1 fig|1265868.3.peg.102 590 593 yes 1890830 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1203257 Streptomyces sp. AA1529 Bacteria 518186495 WP_019356703.1 602 604 yes 1890831 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 559778211 WP_023585915.1 640 646 yes 1890832 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1132442 Bacillus sp. 37MA Bacteria 517202889 WP_018391707.1 583 583 yes 1890833 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4558 Sorghum bicolor Plants UP000000768 UP000018409 242038557, 449632353, 241920527 AGF08968.1, EER93671.1 XP_002466673.1 550 640 yes 1890834 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116044 Escherichia coli, Escherichia coli P0299438.9 Bacteria UP000036210, UP000012396 485872819, 476938172 ENC27468.1 WP_001469634.1 fig|1116044.3.peg.4245 626 631 yes 1890835 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 551947 Bradyrhizobium sp. STM 3843 Bacteria UP000002686 365419576 fig|551947.3.peg.5891 223 232 no 1890836 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 378211 Methyloversatilis universalis Bacteria 517041792 WP_018230610.1 638 638 yes 1890837 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144663 Acinetobacter sp. CIP 102082 Bacteria UP000018448 490915884, 479949079 ENU95044.1 WP_004777787.1 fig|1144663.3.peg.2274 626 631 yes 1890838 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111781 Leptolyngbya sp. PCC 7376 Bacteria UP000010389 504948026, 427356657 AFY39380.1 WP_015135128.1 fig|111781.3.peg.3542 460 461 yes 1890839 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454, 1131731 Bacillus azotoformans, Bacillus azotoformans LMG 9581 Bacteria UP000006315 489425561, 409930187 EKN67190.1 WP_003331236.1 fig|1131731.3.peg.2030 594 594 yes 1890840 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59803 Sphingomonas echinoides Bacteria 498091859 WP_010406015.1 629 637 yes 1890841 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 138595, 1125712 Olsenella profusa, Olsenella profusa F0195 Bacteria UP000016638 545597176, 544350819 ERL09555.1 WP_021725537.1 436 437 yes 1890842 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 271065, 1091494 Methylomicrobium sp. 20Z, Methylomicrobium alcaliphilum 20Z Bacteria UP000008315 503913164, 357404025, 351716690 WP_014147158.1, YP_004915949.1 fig|271065.3.peg.667 621 622 yes 1890843 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 182262, 1331007 Agarivorans albus, Agarivorans albus MKT 106 Bacteria UP000014461 511823033, 511671978 WP_016402004.1 637 645 yes 1890844 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47880, 743720 Pseudomonas fulva, Pseudomonas fulva 12-X Bacteria UP000032068, UP000000686 503559160, 333117600 AEF24114.1 WP_013793236.1 fig|743720.3.peg.4148 627 628 yes 1890845 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 981384 Ruegeria sp. TW15 Bacteria 498123393 WP_010437549.1 594 599 yes 1890846 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158318 Desulfurobacterium sp. TC5-1 Bacteria 551219496 WP_022847434.1 434 434 yes 1890847 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 165694, 687861 Bartonella schoenbuchensis, Bartonella schoenbuchensis R1 Bacteria 631776137, 319408262 603 612 yes 1890848 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116069, 1116068 Escherichia coli, Escherichia coli P0301867.5, Escherichia coli P0301867.4 Bacteria UP000036210, UP000012410, UP000012308 485897233, 477433658, 476728542 ENG98017.1, ENA33320.1 WP_001487709.1 fig|1116068.3.peg.4748, fig|1116069.3.peg.4790 626 631 yes 1890849 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 655186 uncultured SUP05 cluster bacterium Environmental samples UP000009383 269468766 EEZ80378.1 195 196 no 1890850 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 859, 1441736, 1441732, 1441734 Fusobacterium necrophorum, Fusobacterium necrophorum BFTR-2, Fusobacterium necrophorum BL, Fusobacterium necrophorum BFTR-1 Bacteria UP000027094, UP000027473, UP000027210 737950357, 635326315, 635315495, 635311499 KDE74855.1, KDE65127.1, KDE61606.1 WP_035914269.1 433 433 yes 1890851 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34085, 1228997 Riemerella anatipestifer, Riemerella anatipestifer RA-CH-1 Bacteria UP000060579, UP000006276 504751386, 403313339 AFR36180.1 WP_014938488.1 fig|1228997.3.peg.1585 618 618 yes 1890852 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1042376 Flavobacteriaceae bacterium S85 Bacteria 497822743 WP_010136899.1 620 620 yes 1890853 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 90270, 925777 Xanthomonas gardneri, Xanthomonas gardneri ATCC 19865 Bacteria UP000035578, UP000005023 493495218, 821788343, 821775926, 821768773, 821762691, 821759941, 821757887, 821752707, 821748998, 821741716, 821740784, 325548885 KLB42485.1, KLB30493.1, KLB23739.1, KLB17969.1, KLB15425.1, KLB13548.1, KLB08623.1, KLB05132.1, KLA98163.1, KLA97274.1, EGD19827.1 WP_006449838.1 624 625 yes 1890854 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310641, 1217634, 1217629, 903921 Acinetobacter baumannii, Acinetobacter baumannii 1440422, Acinetobacter baumannii NIPH 410, Acinetobacter baumannii NIPH 80, Acinetobacter baumannii Naval-82 Bacteria UP000028632, UP000021090, UP000014561, UP000013021, UP000002844 446995608, 587863325, 514155640, 480128876, 410407342 EXB53097.1, EPG35193.1, ENW66398.1, EKP59328.1 WP_001072864.1 fig|903921.3.peg.1032, fig|1217634.3.peg.3548, fig|1217629.3.peg.3784, fig|1221252.3.peg.2395 621 625 yes 1890855 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310693, 1310750, 1310701, 1310694, 1310563, 1310564 Acinetobacter baumannii, Acinetobacter baumannii 655378, Acinetobacter baumannii 1064293_45, Acinetobacter baumannii 268680, Acinetobacter baumannii 232184, Acinetobacter baumannii 972082, Acinetobacter baumannii 1043794 Bacteria UP000028632, UP000020453, UP000020855, UP000020255, UP000020591, UP000023228, UP000021692 446995609, 602191369, 589420051, 588238593, 588224049, 588113340, 587984089 EYT20535.1, EXH04248.1, EXF10530.1, EXE96541.1, EXD91703.1, EXC68529.1 WP_001072865.1 621 625 yes 1890856 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 470 Acinetobacter baumannii Bacteria UP000028632 446995600 WP_001072856.1 262 266 no 1890857 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 909768, 470, 1439317, 1310779, 1310734, 1310692, 1310665, 1310599, 1310626, 903929, 903930, 903890 Acinetobacter baumannii, Acinetobacter baumanii BIDMC 57, Acinetobacter baumannii 1424608, Acinetobacter baumannii 216872, Acinetobacter baumannii 532279, Acinetobacter baumannii 1525283, Acinetobacter baumannii 781407, Acinetobacter baumannii 21871, Acinetobacter baumannii OIFC087, Acinetobacter baumannii OIFC099, Acinetobacter baumannii OIFC032 Bacteria UP000028632, UP000027208, UP000020320, UP000022744, UP000020528, UP000022266, UP000022243, UP000023480, UP000002845, UP000002835, UP000006612 446995601, 794655527, 742929632, 636481920, 593578342, 589494869, 588212144, 588156079, 588072647, 587879165, 410384368, 410380201, 400382694 KJX73023.1, AJB49687.1, KDM58267.1, EXR61124.1, EXH75642.1, EXE84871.1, EXE30817.1, EXD53572.1, EXB68143.1, EKP36878.1, EKP32790.1, EJP41372.1 WP_001072857.1 fig|903890.3.peg.635, fig|1221308.3.peg.3836, fig|903929.3.peg.2444, fig|903930.3.peg.3030 621 625 yes 1890858 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 470 Acinetobacter baumannii Bacteria UP000028632 446995602 WP_001072858.1 344 348 no 1890859 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470 Acinetobacter baumannii Bacteria UP000028632 446995603 WP_001072859.1 621 625 yes 1890860 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1311137, 1311142, 1311135, 1310633, 1311097, 1311117, 1311091, 1311096, 1311095, 1311093, 1311092, 1311136, 1311090, 1311089, 1311088, 1311115, 1311116, 1311144, 1310598, 1310592, 1311108, 1311109, 1311111, 1311145, 1311143, 1311110, 1311112, 1311141, 1311024, 1311015, 1311016, 1311017, 1311018, 1311019, 1311020, 1311022, 1311023, 1310760, 1310769, 1310771, 1310745, 1310744, 1310737, 1310742, 1310828, 1310691, 1310676, 1310588, 1310595, 1310596, 1310590, 1310571, 1310624 Acinetobacter baumannii, Acinetobacter baumannii 42057_5, Acinetobacter baumannii 45052_2, Acinetobacter baumannii 42057_3, Acinetobacter baumannii 940793, Acinetobacter baumannii 45075_10, Acinetobacter baumannii 25569_10, Acinetobacter baumannii 45075_4, Acinetobacter baumannii 45075_9, Acinetobacter baumannii 45075_8, Acinetobacter baumannii 45075_6, Acinetobacter baumannii 45075_5, Acinetobacter baumannii 42057_4, Acinetobacter baumannii 45075_3, Acinetobacter baumannii 45075_2, Acinetobacter baumannii 45075_1, Acinetobacter baumannii 25569_8, Acinetobacter baumannii 25569_9, Acinetobacter baumannii 45052_4, Acinetobacter baumannii 1121032, Acinetobacter baumannii 1039621, Acinetobacter baumannii 25569_1, Acinetobacter baumannii 25569_2, Acinetobacter baumannii 25569_4, Acinetobacter baumannii 45052_5, Acinetobacter baumannii 45052_3, Acinetobacter baumannii 25569_3, Acinetobacter baumannii 25569_5, Acinetobacter baumannii 45052_1, Acinetobacter baumannii 25493_10, Acinetobacter baumannii 25493_1, Acinetobacter baumannii 25493_2, Acinetobacter baumannii 25493_3, Acinetobacter baumannii 25493_4, Acinetobacter baumannii 25493_5, Acinetobacter baumannii 25493_6, Acinetobacter baumannii 25493_8, Acinetobacter baumannii 25493_9, Acinetobacter baumannii 1406589, Acinetobacter baumannii 1276470-86, Acinetobacter baumannii 1058283, Acinetobacter baumannii 480175, Acinetobacter baumannii 1237893, Acinetobacter baumannii 1271213, Acinetobacter baumannii 1188188, Acinetobacter baumannii 472237-120, Acinetobacter baumannii 42887, Acinetobacter baumannii 43926, Acinetobacter baumannii 562700, Acinetobacter baumannii 29280, Acinetobacter baumannii 1075025, Acinetobacter baumannii 1040094, Acinetobacter baumannii 1032241, Acinetobacter baumannii 1202252 Bacteria UP000028632, UP000027057, UP000027123, UP000027213, UP000027319, UP000027245, UP000027127, UP000027291, UP000027185, UP000027052, UP000027091, UP000027301, UP000027307, UP000027247, UP000027065, UP000027343, UP000024235, UP000024009, UP000024268, UP000021418, UP000022565, UP000023552, UP000023549, UP000023546, UP000023545, UP000023558, UP000022380, UP000022020, UP000023540, UP000020360, UP000022763, UP000021333, UP000021557, UP000023422, UP000021059, UP000023214, UP000020471, UP000023007, UP000023051, UP000021895, UP000022771, UP000023511, UP000021383, UP000022451, UP000023246, UP000020052, UP000023177, UP000020622, UP000020530, UP000020315, UP000023445, UP000020646, UP000022350, UP000019968 446995604, 630631834, 630626260, 630621579, 630473237, 630455576, 630428903, 630391538, 630385161, 630382958, 629041824, 629036186, 629021257, 629012616, 629008084, 629001262, 610957791, 610951637, 610928668, 602211054, 602210499, 601399863, 601391590, 601389923, 601381947, 601381741, 601367075, 601338895, 601333912, 598622844, 598615475, 598608801, 598607169, 598602641, 598596757, 598594927, 598587396, 598579078, 593680097, 593557194, 593499694, 589526962, 589442939, 589434346, 589424871, 589168739, 588209666, 588179121, 588059777, 588046979, 588022068, 587977544, 587972613, 587786246 KCZ26789.1, KCZ21670.1, KCZ17343.1, KCX85139.1, KCX69494.1, KCX45972.1, KCX11144.1, KCX04876.1, KCX02733.1, KCW38615.1, KCW33270.1, KCW19653.1, KCW11381.1, KCW06964.1, KCW00373.1, EZI64772.1, EZI58805.1, EZI36761.1, EYT39978.1, EYT39433.1, EYS48753.1, EYS40704.1, EYS39070.1, EYS31403.1, EYS31204.1, EYS17319.1, EYR90111.1, EYR85453.1, EYD68351.1, EYD61701.1, EYD55269.1, EYD53739.1, EYD49454.1, EYD43786.1, EYD42033.1, EYD35083.1, EYD27388.1, EXS58643.1, EXR40758.1, EXQ85459.1, EXI07060.1, EXH25842.1, EXH17871.1, EXH08939.1, EXG14319.1, EXE82453.1, EXE52974.1, EXD41112.1, EXD28755.1, EXD05106.1, EXC62221.1, EXC57453.1, EXA79273.1 WP_001072860.1 621 625 yes 1890861 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1398971 Acinetobacter baumannii, Acinetobacter baumannii UH5107 Bacteria UP000028632, UP000018963 446995606, 741465460, 741461812, 741458059, 741370237, 571687467 KHW79939.1, KHW76489.1, KHW72900.1, KHV88230.1, ETQ77119.1 WP_001072862.1 621 625 yes 1890862 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1455315, 1217633, 903902 Acinetobacter baumannii, Acinetobacter baumannii LAC-4, Acinetobacter baumannii NIPH 335, Acinetobacter baumannii OIFC098 Bacteria UP000028632, UP000024059, UP000013036, UP000007987 446995607, 725884779, 607868890, 480102790, 408693042 AIY38884.1, EZF14161.1, ENW40831.1, EKL38654.1 WP_001072863.1 fig|1217633.3.peg.3460, fig|903902.3.peg.3492 621 625 yes 1890863 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 564 575 yes 1890864 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 105481 Poa secunda Plants 12240033 AAG49550.1 481 643 yes 1890865 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1435146 Morganella sp. EGD-HP17 Fungi UP000020722 738468653, 570277760 ETO41410.1 WP_036419167.1 620 649 yes 1890866 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 937777 Deinococcus peraridilitoris DSM 19664 Bacteria UP000010467 429128797 AFZ65812.1 fig|937777.3.peg.217 605 611 yes 1890867 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263052 Bacteroides plebeius CAG:211 Environmental samples UP000018372 547321248, 524221014 WP_022052533.1 566 566 yes 1890868 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 298657, 1117319 Pseudoalteromonas spongiae, Pseudoalteromonas spongiae UST010723-006 Bacteria UP000016503 498246940, 540292259 ERG53277.1 WP_010561096.1 643 652 yes 1890869 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 189 Novospirillum itersonii Bacteria 518475424 WP_019645631.1 616 618 yes 1890870 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158169 Thioalkalivibrio sp. ALE9 Bacteria 517709075 WP_018879283.1 627 629 yes 1890871 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36819, 1238180 Amycolatopsis azurea, Amycolatopsis azurea DSM 43854 Bacteria UP000014137 491302568, 449419917 EMD25434.1 WP_005160571.1 fig|1238180.3.peg.4843 545 547 yes 1890872 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1207063 Oceanibaculum indicum P24 Bacteria UP000006746 407202282 EKE72275.1 fig|1207063.3.peg.2809 606 612 yes 1890873 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 761194 Pseudonocardia sp. P1 Bacteria 497927877 WP_010242033.1 544 548 yes 1890874 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 514866014 WP_016604534.1 419 430 yes 1890875 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 367189, 797209 Haladaptatus paucihalophilus, Haladaptatus paucihalophilus DX253 Archaea 516846707 WP_018128681.1 E7QSQ5 E7QSQ5_9EURY 458 480 yes 1890876 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 457403 Fusobacterium nucleatum, Fusobacterium sp. 11_3_2 Bacteria UP000004160 495968966, 336163976 EGN66890.1 WP_008693545.1 fig|457403.3.peg.1585 433 433 yes 1890877 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 59201, 1387330, 1323580, 1321366, 1194158, 941190, 997333, 997334 Salmonella enterica, Salmonella enterica subsp. enterica, Salmonella enterica subsp. enterica serovar 9,12:l,v:- str. 94293, Salmonella enterica subsp. enterica serovar Oranienburg str. S-76, Salmonella enterica subsp. enterica serovar Saintpaul str. S-70, Salmonella enterica subsp. enterica serovar Eastbourne str. CFSAN001084, Salmonella enterica subsp. enterica serovar Chester str. ATCC 11997, Salmonella enterica subsp. enterica serovar Oranienburg str. 0250, Salmonella enterica subsp. enterica serovar Oranienburg str. 701 Bacteria UP000054489, UP000033855, UP000026604, UP000017752, UP000017763, UP000017527, UP000017541, UP000017550, UP000017288 555222223, 735752220, 619500854, 556545278, 556539757, 554405007, 554280022, 554181125, 554177011 KHP22539.1, KAJ98417.1, ESP77315.1, ESP72266.1, ESJ34642.1, ESH15699.1, ESG20250.1, ESG16261.1 WP_023214836.1 626 631 yes 1890878 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2188, 456320 Methanococcus voltae, Methanococcus voltae A3 Archaea UP000007722 502945883, 297378976 ADI37131.1 WP_013180859.1 D7DQK4 D7DQK4_METV3 426 426 yes 1890879 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1502, 883064 Clostridium perfringens, Clostridium perfringens F262 Bacteria UP000059070, UP000005358 489575942, 380305654 EIA17931.1 WP_003480388.1 fig|883064.3.peg.679 436 436 yes 1890880 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1224, 1440764, 180282 Thermomonas brevis DSM 15422, Delftia tsuruhatensis Bacteria UP000027696 515976844, 822135608, 657324487 KLD87984.1, KEH07007.1 WP_017407427.1 625 647 yes 1890881 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 674, 1400797, 1400798 Vibrio mimicus, Vibrio mimicus CAIM 1882, Vibrio mimicus CAIM 1883 Bacteria UP000053748, UP000016868, UP000016852 550010120, 548722104, 548721848 ERM63429.1, ERM63284.1 WP_022577360.1 640 646 yes 1890882 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 518, 1331202 Bordetella bronchiseptica, Bordetella bronchiseptica 99-R-0433 Bacteria UP000064190, UP000026567 704407679, 627907794 KCV62011.1 WP_033465397.1 636 637 yes 1890883 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29581 Janthinobacterium lividum Bacteria UP000023814 736745401, 612082010 EZP40773.1 WP_034749177.1 636 637 yes 1890884 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29288, 694430 Natronococcus occultus, Natronococcus occultus SP4 Archaea UP000010878 505133464, 435846655, 433672923 AGB37115.1 WP_015320566.1, YP_007308905.1 L0JXT1 L0JXT1_9EURY 494 598 yes 1890885 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 262776, 1165867 Rhodococcus imtechensis, Rhodococcus imtechensis RKJ300 = JCM 13270 Bacteria UP000006447 494511849, 383833139 EID72605.1 WP_007301307.1 fig|1165867.3.peg.7522 541 548 yes 1890886 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 102125 Xenococcus sp. PCC 7305 Bacteria UP000011203 493556809, 442793131 ELS02589.1 WP_006510308.1 fig|102125.3.peg.3134 459 461 yes 1890887 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67825, 637910 Citrobacter rodentium, Citrobacter rodentium ICC168 Bacteria UP000032873, UP000001889 502671936, 756136278, 282950787 KIQ49065.1 WP_012907750.1 fig|637910.3.peg.3576 626 631 yes 1890888 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1194156 Salmonella enterica, Salmonella enterica subsp. enterica serovar Havana str. CFSAN001082 Bacteria UP000054489, UP000017294 555275425, 554417198 ESJ44487.1 WP_023254141.1 626 631 yes 1890889 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 431554 Spirosoma spitsbergense Bacteria 522090135 WP_020601344.1 625 625 yes 1890890 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28141, 1138308 Cronobacter sakazakii, Cronobacter sakazakii ES15 Bacteria UP000027472, UP000002877 504542687, 387853095 AFK01193.1 WP_014729789.1 fig|1138308.5.peg.3619 626 633 yes 1890891 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 209639, 1318628 Marinobacter lipolyticus, Marinobacter lipolyticus SM19 Bacteria UP000016540 501089598, 499159551 EON90656.1 WP_012139836.1 fig|1318628.3.peg.3585 622 625 yes 1890892 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 167539, 1219 Prochlorococcus marinus subsp. marinus str. CCMP1375, Prochlorococcus marinus Bacteria UP000001420 33241220, 499438456, 33238750, 47606127 AAQ00815.1 NP_876162.1, WP_011125920.1 Q7V9Q8 THIC_PROMA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 565214 fig|167539.1.peg.1768 466 468 yes 1890893 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 149715, 443254 Marinitoga piezophila, Marinitoga piezophila KA3 Bacteria UP000007161 504062384, 372101402 AEX85306.1 WP_014296378.1 fig|443254.7.peg.870 432 433 yes 1890894 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36841 Clostridium glycolicum Bacteria 517418256 WP_018589904.1 434 434 yes 1890895 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263034 Akkermansia muciniphila CAG:154 Environmental samples UP000018106 547787670, 524406710 WP_022198239.1 607 607 yes 1890896 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68204, 1284664 Streptomyces gancidicus, Streptomyces gancidicus BKS 13-15 Bacteria UP000011732 493097219, 455648244 EMF27124.1 WP_006134029.1 fig|1284664.3.peg.4098 595 598 yes 1890897 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 394104 Endoriftia persephone 'Hot96_1+Hot96_2' Bacteria 110589332 ABG77175.1 181 197 no 1890898 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 260552 Microbulbifer agarilyticus Bacteria 497817432 WP_010131588.1 630 645 yes 1890899 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 414, 243233 Methylococcus capsulatus, Methylococcus capsulatus str. Bath Bacteria UP000006821 499264525, 53756940, 81680977 AAU91231.1 WP_010961919.1 Q603T9 THIC_METCA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 764537 fig|243233.4.peg.2636 622 624 yes 1890900 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1420917 Marinobacter sp. R9SW1 Bacteria UP000035081 752688239, 582029478 AHI32813.1 WP_041336140.1 622 625 yes 1890901 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570, 573, 1409964, 72407, 1406314, 1329843, 1438811, 1438803, 1438795, 1438788, 1438789, 1438772, 1438798, 1438805, 1438786, 1328371, 1328379, 1328381, 1328405, 1328415, 1400163, 1400166, 1400167, 1400169, 1400173, 1400177, 1431455, 1328337, 1328362, 1328364, 1328366, 1328368, 1328370, 1328378, 1328380, 1328384, 1328390, 1328391, 1328416, 1328418, 1328420, 1328427, 1269006, 1381121, 1284818, 1284817, 1284834, 1284833, 1236101, 1226115, 1203547, 1203545, 665944, 1379687 Klebsiella pneumoniae, Klebsiella pneumoniae MRSN 3852, Klebsiella pneumoniae subsp. pneumoniae, Klebsiella pneumoniae subsp. pneumoniae PittNDM01, Enterobacter sp. BIDMC 33B, Klebsiella pneumoniae UCI 68, Klebsiella pneumoniae UCI 56, Klebsiella pneumoniae MGH-72, Klebsiella pneumoniae MGH 65, Klebsiella pneumoniae MGH 66, Klebsiella pneumoniae CHS 66, Klebsiella pneumoniae MGH-75, Klebsiella pneumoniae UCI 60, Klebsiella pneumoniae MGH 63, Klebsiella pneumoniae MGH 35, Klebsiella pneumoniae MGH 47, Klebsiella pneumoniae BWH 2, Klebsiella pneumoniae BIDMC 11, Klebsiella pneumoniae BIDMC 18D, Klebsiella pneumoniae BIDMC 46a, Klebsiella pneumoniae BIDMC 48, Klebsiella pneumoniae BIDMC 51, Klebsiella pneumoniae BIDMC 53, Klebsiella pneumoniae UCI 20, Klebsiella pneumoniae UCI 26, Klebsiella pneumoniae NB60, Hafnia alvei BIDMC 31, Klebsiella pneumoniae MGH 17, Klebsiella pneumoniae MGH 19, Klebsiella pneumoniae MGH 21, Klebsiella pneumoniae MGH 30, Klebsiella pneumoniae MGH 32, Klebsiella pneumoniae MGH 46, Klebsiella pneumoniae MGH 48, Klebsiella pneumoniae BWH 28, Klebsiella pneumoniae UCICRE 2, Klebsiella pneumoniae UCICRE 4, Klebsiella pneumoniae BIDMC 21, Klebsiella pneumoniae BIDMC 23, Klebsiella pneumoniae BIDMC 25, Klebsiella pneumoniae BIDMC 41, Escherichia coli 909957, Klebsiella pneumoniae 303K, Klebsiella pneumoniae UHKPC179, Klebsiella pneumoniae UHKPC57, Klebsiella pneumoniae KP-11, Klebsiella pneumoniae KP-7, Klebsiella pneumoniae JHCK1, Klebsiella pneumoniae subsp. pneumoniae KpQ3, Klebsiella pneumoniae subsp. pneumoniae WGLW5, Klebsiella pneumoniae subsp. pneumoniae WGLW2, Klebsiella sp. 4_1_44FAA, Klebsiella pneumoniae BJ1-GA Bacteria UP000036212, UP000034728, UP000060052, UP000028499, UP000027897, UP000027560, UP000027543, UP000027557, UP000027537, UP000027498, UP000027526, UP000024494, UP000024667, UP000025113, UP000021604, UP000021859, UP000020864, UP000020189, UP000022601, UP000023457, UP000022172, UP000021350, UP000023484, UP000021199, UP000020691, UP000019274, UP000021171, UP000017594, UP000017386, UP000017630, UP000017507, UP000017519, UP000017314, UP000017383, UP000017312, UP000017442, UP000017309, UP000017385, UP000017319, UP000017438, UP000017506, UP000017394, UP000017107, UP000014879, UP000014274, UP000014292, UP000014278, UP000012120, UP000011948, UP000004475, UP000004779, UP000004888, UP000019187 490282339, 839818712, 839810861, 839798982, 839778224, 839711975, 839694584, 839690569, 839681660, 839660154, 839659963, 839650113, 839619911, 839617678, 839594594, 839591235, 839585141, 839392788, 839242196, 839232473, 839215237, 839152680, 839127706, 839043375, 838998262, 838977105, 828954626, 820953039, 816085243, 770610019, 770609312, 736265830, 727657158, 723249693, 695190711, 695174242, 694252918, 694252239, 685504381, 674136407, 667710877, 656065034, 636468658, 636436204, 636399228, 636373386, 636367331, 636279570, 612329510, 612311618, 612282731, 583705246, 583687783, 583686144, 583617949, 583584788, 583557477, 583541407, 583538565, 583528524, 583507101, 583479556, 583437081, 575535700, 555210651, 555190376, 555190147, 555151940, 555149867, 555115522, 555106028, 555105933, 555084814, 555066185, 555020516, 555009257, 555001696, 554974642, 553376475, 549469501, 519543158, 510300794, 509684345, 509567473, 459674764, 407809810, 405610189, 405607838, 363645686, 758070604, 573070964 KMI91215.1, KMI83426.1, KMI71650.1, KMI51037.1, KMH85452.1, KMH68288.1, KMH64321.1, KMH55519.1, KMH34503.1, KMH34318.1, KMH24593.1, KMG94718.1, KMG92538.1, KMG69750.1, KMG66429.1, KMG60430.1, KME69766.1, KMD20613.1, KMD10991.1, KMB93941.1, KMB32061.1, KMB07314.1, KMA23721.1, KLZ78972.1, KLZ57978.1, AKL29061.1, AKH01550.1, KKJ32753.1, KJL07849.1, KJL07165.1, KHQ21930.1, KHF52564.1, AIX82317.1, KGK51365.1, AIT01334.1, KGJ38437.1, KGJ37782.1, KGB20298.1, AIK81679.1, AIG84126.1, KEF23283.1, KDM45158.1, KDM12983.1, KDL76346.1, KDL50686.1, KDL44696.1, KDK57458.1, EZR21777.1, EZR04160.1, EZQ75944.1, EWF67384.1, EWF50063.1, EWF48435.1, EWE80716.1, EWE47883.1, EWE20794.1, EWE04840.1, EWE02030.1, EWD92049.1, EWD70781.1, EWD43449.1, EWD04793.1, ETX36153.1, ESN52979.1, ESN32856.1, ESN32820.1, ESM94603.1, ESM92553.1, ESM58462.1, ESM49087.1, ESM48994.1, ESM27980.1, ESM10356.1, ESL64943.1, ESL53740.1, ESL46208.1, ESL19341.1, ESB02574.1, ERN59641.1, EPO89986.1, EPA87358.1, EOZ65126.1, EOY65826.1, EMH91381.1, EKF81061.1, EKB82999.1, EKB80790.1, EHL84947.1 WP_004178230.1 fig|1316939.3.peg.85, fig|1284834.3.peg.3721, fig|665944.3.peg.5151, fig|1037890.3.peg.3875, fig|1037908.3.peg.4371, fig|1203547.3.peg.4529, fig|1226115.3.peg.5045, fig|1284817.3.peg.5234, fig|1316938.3.peg.884, fig|1203545.3.peg.23, fig|1236101.6.peg.2411 626 631 yes 1890902 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413502, 1208590 Cronobacter turicensis, Cronobacter turicensis 564 Bacteria UP000009344 495041731, 426289514 WP_007766581.1 626 633 yes 1890903 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 29291, 259564 Methanococcoides burtonii, Methanococcoides burtonii DSM 6242 Archaea UP000001979 499819140, 91712804 ABE52731.1 WP_011499874.1 Q12UZ5 Q12UZ5_METBU fig|259564.8.peg.1757 406 415 no 1890904 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1292024 Desulfovibrio sp. Dsv1 Bacteria 550896106 WP_022656772.1 419 426 no 1890905 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 280699 Cyanidioschyzon merolae strain 10D Plants UP000007014 544211116, 449016270 XP_005535958.1 558 673 yes 1890906 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992166 Yersinia pestis, Yersinia pestis PY-66 Bacteria UP000000815 UP000031825, UP000003454 488355666, 391626380 EIS66741.1 WP_002425051.1 208 228 no 1890907 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632, 992166 Yersinia pestis, Yersinia pestis PY-66 Bacteria UP000000815 UP000031825, UP000003454 488355667, 391626363 EIS66727.1 WP_002425052.1 fig|992173.3.peg.4071, fig|992157.3.peg.3912, fig|992167.3.peg.3761, fig|992159.3.peg.3720, fig|992133.3.peg.4185, fig|992146.3.peg.4076, fig|992147.3.peg.4083, fig|992170.3.peg.4053, fig|992171.3.peg.4041, fig|992174.3.peg.3910, fig|992139.3.peg.4156, fig|992166.3.peg.3685, fig|992160.3.peg.3896, fig|992178.3.peg.4106, fig|992162.3.peg.3907, fig|992136.3.peg.3935, fig|992185.3.peg.3774, fig|992150.3.peg.3812, fig|992176.3.peg.3875, fig|992154.3.peg.3836, fig|992137.3.peg.4106, fig|992177.3.peg.4111, fig|992145.3.peg.4172, fig|992149.3.peg.4129, fig|992144.3.peg.3952 442 455 yes 1890908 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 196, 1093099, 1273266, 983328, 688354 Campylobacter fetus, Campylobacter fetus subsp. venerealis 97/608, Campylobacter fetus subsp. venerealis cfvi03/293, Campylobacter fetus subsp. venerealis NCTC 10354, Campylobacter fetus subsp. venerealis str. 84-112 Bacteria UP000031165, UP000029503, UP000018924, UP000003306, UP000032729 488937536, 691216787, 570722391, 342327085, 577005731 AIR80077.1, AHE93752.1, EGU23569.1 WP_002848611.1 449 450 yes 1890909 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 224308 Bacillus subtilis subsp. subtilis str. 168 Bacteria UP000001570 UP000030629 860678 AAA68243.1 P45740 THIC_BACSU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6132113, 37411, 6127580, 6136503 fig|224308.1.peg.878 590 590 no 1890910 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116098 Escherichia coli, Escherichia coli p0305293.10 Bacteria UP000036210, UP000012428 487387588, 477357432 ENG26099.1 WP_001659322.1 fig|1116098.3.peg.4630 626 631 yes 1890911 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1458461 bacterium Ec32 Bacteria UP000032160 763068005, 610512545 WP_043949714.1 611 626 yes 1890912 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 212663 Vibrio tasmaniensis Bacteria 515674800 WP_017107400.1 640 649 yes 1890913 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 445 447 yes 1890914 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 158877, 911023, 1002368 Yokenella regensburgei, Yokenella regensburgei ATCC 49455, Yokenella regensburgei ATCC 43003 Bacteria UP000028655, UP000003044 493870012, 669014209, 364574576 KFD24975.1, EHM52028.1 WP_006816562.1 fig|1002368.3.peg.20 626 632 yes 1890915 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 742741 Clostridium symbiosum WAL-14673 Bacteria UP000005841 323500876 EGB16795.1 453 458 yes 1890916 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 408, 272630 Methylobacterium extorquens, Methylobacterium extorquens AM1 Bacteria UP000009081 502289313, 240008139 ACS39365.1 WP_012752516.1 fig|272630.7.peg.1502 625 630 yes 1890917 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37636 Thermus scotoductus Bacteria UP000053099 518380707 WP_019550914.1 433 435 yes 1890918 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1094755 Bartonella sp. DB5-6 Bacteria UP000002643 494816712, 395414311 EJF80760.1 WP_007552120.1 fig|1094755.3.peg.286 601 610 yes 1890919 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40576, 1379676, 406818 Xenorhabdus bovienii, Xenorhabdus bovienii str. Jollieti, Xenorhabdus bovienii SS-2004 Bacteria UP000032930, UP000028510, UP000002045 502755326, 284852073, 666603605, 289176335 ADC02297.1 WP_012990310.1 fig|406818.4.peg.3636 625 657 yes 1890920 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 562, 1405293 Escherichia coli, Escherichia coli ATCC BAA-2209 Bacteria UP000036210, UP000018675 565902471, 564855087 ETD64563.1 WP_023981488.1 80 81 no 1890921 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314277 Marinomonas sp. MED121 Bacteria UP000003436 86163347 EAQ64623.1 640 689 yes 1890922 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1266844, 438, 940265, 1006554, 634459, 634458, 634457, 634456, 634455, 634454, 634453, 634452 Acetobacter pasteurianus 386B, Acetobacter pasteurianus, Acetobacter pasteurianus subsp. pasteurianus LMG 1262, Acetobacter pasteurianus NBRC 101655, Acetobacter pasteurianus IFO 3283-12, Acetobacter pasteurianus IFO 3283-01-42C, Acetobacter pasteurianus IFO 3283-32, Acetobacter pasteurianus IFO 3283-26, Acetobacter pasteurianus IFO 3283-22, Acetobacter pasteurianus IFO 3283-07, Acetobacter pasteurianus IFO 3283-03, Acetobacter pasteurianus IFO 3283-01 Bacteria UP000015386, UP000037575, UP000015606, UP000015603, UP000000953, UP000000952, UP000001621, UP000000951, UP000000950, UP000000949, UP000001620, UP000000948 529231327, 489722721, 528529123, 371478943, 371458159, 256655970, 256652916, 256649926, 256646873, 256643818, 256640763, 256637709, 256634653 YP_008392142.1, WP_003626837.1 fig|634452.3.peg.2604, fig|940265.3.peg.1251, fig|634458.3.peg.2542, fig|634457.3.peg.2609, fig|634456.3.peg.2608, fig|634459.3.peg.2614, fig|634455.3.peg.2610, fig|1006554.3.peg.2553, fig|634453.3.peg.2607, fig|634454.3.peg.2611 606 625 yes 1890923 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1367477 Bacillus infantis NRRL B-14911 Bacteria UP000017805 549640184, 548703921 AGX03281.1 WP_022543563.1 587 587 yes 1890924 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 700015 Coriobacterium glomerans PW2 Bacteria UP000006851 328456133 AEB07327.1 fig|700015.3.peg.1317 461 464 yes 1890925 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1202448 Enterobacter sp. Ag1 Bacteria UP000005486 495735581, 394729876 EJF29803.1 WP_008460160.1 fig|1202448.3.peg.3472 626 633 yes 1890926 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 984236 Salmonella enterica subsp. enterica serovar Kentucky str. ATCC 9263 Bacteria UP000017492 554240788 ESG77729.1 626 631 yes 1890927 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 556484 Phaeodactylum tricornutum CCAP 1055/1 Plants UP000000759 219123676, 217406107 EEC46047.1 XP_002182146.1 546 619 yes 1890928 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632955, 421052 Acinetobacter sp. A1PC16, Acinetobacter sp. G30 Bacteria UP000014568 514966423, 514101665 EPF81641.1 WP_016654725.1 fig|421052.3.peg.275 622 627 yes 1890929 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547043 Bifidobacterium pseudocatenulatum DSM 20438 Bacteria UP000028994 225157255 EEG70594.1 fig|547043.6.peg.1152 629 871 yes 1890930 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28182, 1193054 Leptospira noguchii, Leptospira noguchii str. Cascata Bacteria UP000018512 490588992, 474493831 EMS82214.1 WP_004454012.1 fig|1193054.3.peg.4745 442 496 yes 1890931 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 544 547 yes 1890932 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35517, 1321814 Eubacterium brachy, Eubacterium brachy ATCC 33089 Bacteria UP000017536 553956124, 553715930 ESE31001.1 WP_023152593.1 436 437 yes 1890933 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358, 1336745 Agrobacterium tumefaciens, Agrobacterium radiobacter DSM 30147 Bacteria UP000064781, UP000019107 523695032, 523372772 EPR07396.1 WP_020813439.1 600 607 yes 1890934 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81033, 1280953 Hyphomonas oceanitis, Hyphomonas oceanitis SCH89 Bacteria UP000024942 737565293, 630956766 KDA02794.1 WP_035537649.1 622 631 yes 1890935 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1470589 Pseudomonas sp. RIT288 Bacteria UP000023994 835651506, 612069611 EZP28628.1 WP_047600736.1 628 629 yes 1890936 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 473781 Sphingomonas sp. LH128 Bacteria UP000004402 496105288, 402262903 EJU12848.1 WP_008829795.1 409 415 no 1890937 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47420, 795665, 65786 Hydrogenophaga sp. PBC, Hydrogenophaga intermedia Bacteria UP000005985, UP000028878 497203632, 388265016, 633889169 EIK90576.1 WP_009517894.1 fig|795665.3.peg.2393 624 632 yes 1890938 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 126385, 1141661 Providencia alcalifaciens, Providencia alcalifaciens Dmel2 Bacteria UP000009348 493713422, 414102169 EKT63764.1 WP_006663012.1 fig|1141661.3.peg.3053 623 655 yes 1890939 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1288494 Nitrosospira sp. APG3 Bacteria UP000012179 490278303, 475054631 WP_004174251.1 fig|1288494.3.peg.143 626 635 yes 1890940 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263010 Firmicutes bacterium CAG:227 Environmental samples UP000018294 547898856, 524565692 WP_022303195.1 435 435 yes 1890941 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 72360 Bacillus mojavensis Bacteria 498019325 WP_010333481.1 590 590 yes 1890942 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169144 Bacillus sp. 123MFChir2 Bacteria 518907058 WP_020062933.1 586 586 yes 1890943 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263104, 718255, 657315 Roseburia intestinalis CAG:13, Roseburia intestinalis XB6B4, Roseburia intestinalis M50/1 Environmental samples, Bacteria UP000018030, UP000008953, UP000008807 505334164, 524295913, 291539644, 291535118 WP_015521266.1 433 434 yes 1890944 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36814, 931627 Mycobacterium rhodesiae, Mycobacterium rhodesiae JS60 Bacteria UP000004640 491285189, 353190333 EHB55843.1 WP_005143221.1 fig|931627.3.peg.3048 520 526 yes 1890945 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 339268, 1041522 Mycobacterium colombiense, Mycobacterium colombiense CECT 3035 Bacteria UP000006455 495043601, 400333329 EJO90823.1 WP_007768444.1 544 551 yes 1890946 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4572 Triticum urartu Plants UP000015106 473808483 EMS46732.1 560 603 yes 1890947 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 186802, 1151410, 658657, 908340 Clostridium difficile P28, Erysipelotrichaceae bacterium 21_3, Clostridium sp. HGF2 Bacteria UP000015734, UP000003424, UP000004918 496569809, 531686566, 371658351, 312957201 EQJ63938.1, EHO23633.1, EFR38830.1 WP_009270927.1 fig|658657.3.peg.4103, fig|908340.3.peg.889 435 435 yes 1890948 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992180, 992168, 992154, 992137 Yersinia pestis, Yersinia pestis PY-99, Yersinia pestis PY-72, Yersinia pestis PY-52, Yersinia pestis PY-11 Bacteria UP000000815 UP000031825, UP000003881, UP000002989, UP000004366, UP000006197 488322699, 391707119, 391635366, 391564893, 391470057 EIT38500.1, EIS74537.1, EIS13054.1, EIR27759.1 WP_002392084.1 179 203 no 1890949 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1190574, 935589, 935591 Neisseria meningitidis, Neisseria meningitidis NM151, Neisseria meningitidis NZ-05/33, Neisseria meningitidis M01-240149 Bacteria UP000050419, UP000015825, UP000007482, UP000007480 504393804, 530909937, 325208892, 325201322 EQD08037.1, ADZ04344.1, ADY96776.1 WP_014580906.1 fig|1123521.3.peg.2516, fig|935589.3.peg.2633, fig|1123522.3.peg.1039, fig|935591.3.peg.183, fig|1123520.3.peg.1105 625 633 yes 1890950 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 1203592 Streptomyces sp. HPH0547 Bacteria UP000014390 512670429, 512148831 EPD91332.1 WP_016472104.1 fig|1203592.3.peg.5303 592 593 yes 1890951 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 457425 Streptomyces albus J1074 Bacteria UP000012184 490047076, 477545335, 291355661 AGI89288.1, EFE82563.1 WP_003949438.1 595 597 yes 1890952 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 48664, 1131451 Xanthomonas fragariae, Xanthomonas fragariae LMG 25863 Bacteria UP000013234 488893769, 481586877 ENZ96260.1 WP_002804909.1 fig|1131451.6.peg.1360 624 625 yes 1890953 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 60133, 997353 Prevotella pallens, Prevotella pallens ATCC 700821 Bacteria UP000004123 492913599, 339618039 EGQ22641.1 WP_006043879.1 528 529 yes 1890954 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34103, 1286631 Sphaerotilus natans, Sphaerotilus natans subsp. natans DSM 6575 Bacteria UP000026714 739623190, 633289613 KDB53124.1 WP_037479659.1 612 617 yes 1890955 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280944 Hyphomonas sp. CY54-11-8 Bacteria UP000024460 736761771, 630766141 KCZ48141.1 WP_034765334.1 647 655 yes 1890956 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 32008, 871203, 406819 Burkholderia sp. OP-1, Burkholderia sp. SJ98 Bacteria UP000027451, UP000003359 495625994, 646752359, 413928927 KDR25094.1, EKS68215.1 WP_008350573.1 642 643 yes 1890957 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65555, 1167006 Desulfocapsa sulfexigens, Desulfocapsa sulfexigens DSM 10523 Bacteria UP000011721 505217899, 451907721 AGF79315.1 WP_015405001.1 fig|1167006.5.peg.3008 435 437 yes 1890958 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1760, 1110697 Nocardia asteroides NBRC 15531 Bacteria UP000017048 517879440, 549077779 WP_019049648.1 547 549 yes 1890959 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61305 Nocardiopsis synnemataformans Bacteria 516137150 WP_017567730.1 552 557 yes 1890960 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550 552 yes 1890961 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 921, 639283 Starkeya novella, Starkeya novella DSM 506 Bacteria UP000006633 502932775, 296929439 ADH90248.1 WP_013167751.1 fig|639283.3.peg.2955 600 603 yes 1890962 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537 538 yes 1890963 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28133, 702439 Prevotella nigrescens, Prevotella nigrescens F0103 Bacteria UP000011569 490496178, 444841285 ELX68302.1 WP_004362351.1 fig|702439.3.peg.495 526 526 yes 1890964 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 665937, 1262699 Anaerostipes sp. 3_2_56FAA, Anaerostipes sp. CAG:276 Bacteria, Environmental samples UP000004032, UP000018135 496598889, 316899191, 524495355 EFV21210.1 WP_009290979.1 433 433 yes 1890965 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262941 Roseburia sp. CAG:18 Environmental samples UP000018230 547315396, 524211468 WP_022046954.1 433 434 yes 1890966 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1328419 Klebsiella pneumoniae, Klebsiella pneumoniae BIDMC 24 Bacteria UP000036212, UP000017520 556241792, 555003056 ESL47556.1 WP_023285702.1 626 631 yes 1890967 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1049564 endosymbiont of Tevnia jerichonana (vent Tica) Bacteria UP000005167 345123082 EGW52993.1 fig|1049564.3.peg.3121 447 585 no 1890968 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81985 Capsella rubella Plants UP000029121 565472036, 482562528 EOA26718.1 XP_006293820.1 555 647 4N7Q, 4S29, 4S28, 4S27, 4S26, 4S25 yes 1890969 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 768491 Serratia sp. S4 Bacteria 516502894 WP_017891332.1 633 647 yes 1890970 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2371, 160492 Xylella fastidiosa, Xylella fastidiosa 9a5c Bacteria UP000028529, UP000000812 499196814, 24638289 WP_010894354.1 Q9PC93 THIC_XYLFA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2137509 fig|160492.1.peg.1881 594 601 yes 1890971 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287336 Mesorhizobium sp. LSJC280B00 Bacteria UP000021307 563453837, 562953519 ESW79473.1 WP_023679203.1 596 611 yes 1890972 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 70771, 444157 Thermoproteus neutrophilus, Thermoproteus neutrophilus V24Sta Archaea UP000001694 501318258, 171185000, 170934212 ACB39473.1 WP_012349893.1, YP_001793919.1 B1YCG0 B1YCG0_PYRNV 7321320 fig|444157.3.peg.534 421 443 no 1890973 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 685778 Sphingomonas sp. PR090111-T3T-6A Bacteria 518669456 WP_019831149.1 616 620 yes 1890974 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 160488, 303 Pseudomonas putida KT2440, Pseudomonas putida Bacteria UP000000556, UP000054813 26991600, 499257962, 24986690, 37999610 AAN70489.1 NP_747025.1, WP_010955502.1 Q88DA5 THIC_PSEPK Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 220561 fig|160488.1.peg.4855, fig|1079364.3.peg.385 625 626 yes 1890975 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 837, 1125722, 242619 Porphyromonas gingivalis, Porphyromonas gingivalis W50, Porphyromonas gingivalis W83 Bacteria UP000028798, UP000004270, UP000000588 492522142, 392611727, 34398009, 47606105 EIW94456.1, AAQ67069.1 WP_005873759.1 Q7MT71 THIC_PORGI Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 563298 fig|1125722.3.peg.459, fig|242619.1.peg.1811 587 587 yes 1890976 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33943, 562970 Bacillus tusciae, Bacillus tusciae DSM 2912 Bacteria UP000002368 502839436, 295410627 ADG05119.1 WP_013074412.1 fig|562970.4.peg.364 587 594 yes 1890977 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43306, 1294143 Pseudomonas denitrificans, Pseudomonas denitrificans ATCC 13867 Bacteria UP000012082 505292076, 472251615 AGI26329.1 WP_015479178.1 fig|1294143.3.peg.4528 626 626 yes 1890978 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570, 1328397 Klebsiella pneumoniae UCICRE 14 Bacteria UP000017593 556292412, 555027379 ESL72171.1 WP_023291597.1 626 631 yes 1890979 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 52764, 1094551 Bartonella alsatica, Bartonella alsatica IBS 382 Bacteria UP000008761 492497703, 395408627 EJF75237.1 WP_005865746.1 fig|1094551.3.peg.791 602 608 yes 1890980 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1055352 Streptomyces sp. W007 Bacteria UP000004626 364005785 EHM26846.1 fig|1055352.3.peg.4835 549 550 yes 1890981 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1121721 Gordonia kroppenstedtii Bacteria 516944769 WP_018177680.1 546 553 yes 1890982 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 521720 Pseudomonas sp. HY-24 Bacteria 551346529 WP_022965939.1 626 627 yes 1890983 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 518418734 WP_019588941.1 627 629 yes 1890984 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444081, 1438695, 1444215, 1417796, 1337385, 1281201, 1281175, 1280991, 1182711, 1181745, 1182707, 1182683, 1181781, 1181780, 1433131 Escherichia coli, Escherichia coli 1-392-07_S1_C2, Escherichia coli UCI 65, Escherichia coli 1-110-08_S4_C1, Escherichia coli LAU-EC10, Escherichia coli SCD2, Escherichia coli UMEA 3163-1, Escherichia coli UMEA 3033-1, Escherichia coli HVH 41 (4-2677849), Escherichia coli KTE121, Escherichia coli KTE199, Escherichia coli KTE115, Escherichia coli KTE76, Escherichia coli KTE237, Escherichia coli KTE236, Escherichia coli IS1 Bacteria UP000036210, UP000027629, UP000027244, UP000021515, UP000018753, UP000017336, UP000016026, UP000016286, UP000016002, UP000014159, UP000014102, UP000010503, UP000010681, UP000010533, UP000010621, UP000018892 486202820, 651802300, 635909365, 598690248, 564924919, 553018024, 535589681, 535485452, 534698417, 508456698, 508348297, 431359435, 431154696, 431075236, 431069641, 568388721 KDW78122.1, KDG89813.1, EYD97069.1, ETE20038.1, ESA24982.1, EQX26990.1, EQW24901.1, EQO54067.1, EOW26417.1, EOV19877.1, ELG46074.1, ELE55458.1, ELD82767.1, ELD77966.1 WP_001550405.1 fig|1181781.3.peg.4961, fig|1181745.3.peg.4020, fig|1182711.3.peg.3979, fig|1182707.3.peg.4341, fig|1181780.3.peg.4584, fig|1308540.3.peg.4301, fig|1182683.3.peg.4427 626 631 yes 1890985 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 1218933 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. carotovorum PCC21 Bacteria UP000053038, UP000003783 504726704, 402803987 AFR01625.1 WP_014913806.1 fig|1218933.3.peg.227 631 651 yes 1890986 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 388259, 1230460 Natronorubrum sulfidifaciens, Natronorubrum sulfidifaciens JCM 14089 Archaea 495438801, 445589458 ELY43690.1 WP_008163496.1 L9W2K4 L9W2K4_9EURY 466 480 yes 1890987 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1760, 591158 Streptomyces sp. AA4 Bacteria UP000003970 496375030, 302439512 EFL11328.1 WP_009084020.1 544 547 yes 1890988 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444071, 1444042, 1444147 Escherichia coli, Escherichia coli 2-316-03_S1_C2, Escherichia coli 2-316-03_S1_C1, Escherichia coli 2-005-03_S3_C2 Bacteria UP000036210, UP000027848, UP000027782, UP000027290 693029412, 658678166, 658677134, 632176206 KEJ21775.1, KEJ20805.1, KDA71212.1 WP_032205234.1 626 631 yes 1890989 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913073 Salmonella enterica subsp. enterica serovar Hvittingfoss str. A4-620 Bacteria UP000004517 353583574 EHC43895.1 fig|913073.3.peg.4408 246 247 no 1890990 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 329186, 1341155 Flavobacterium saliperosum, Flavobacterium saliperosum S13 Bacteria UP000018234 559199373, 558900807 ESU28033.1 WP_023575587.1 607 607 yes 1890991 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 72664, 98038 Eutrema salsugineum, Thellungiella halophila Plants UP000030689 567210201, 567210197, 557111189, 557111188, 312282721 ESQ51473.1, ESQ51472.1 XP_006410020.1, XP_006410019.1 555 644 4N7Q, 4S29, 4S28, 4S27, 4S26, 4S25 yes 1890992 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 229731, 358396 Halobiforma lacisalsi, Halobiforma lacisalsi AJ5 Archaea 494241891, 445776401 EMA27380.1 WP_007143756.1 M0L5W2 M0L5W2_9EURY 455 490 yes 1890993 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 369333 Paenibacillus terrigena Bacteria 517588157 WP_018758365.1 573 573 yes 1890994 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29508, 1218585 Leptospira meyeri, Leptospira meyeri serovar Semaranga str. Veldrot Semarang 173 Bacteria UP000011977 523639373, 463324397 EMJ90071.1 WP_020775582.1 fig|1218585.3.peg.348 499 503 yes 1890995 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 440512 Pseudomonas sp. Chol1 Bacteria UP000008490 495843845, 409119631 EKM96007.1 WP_008568424.1 fig|440512.3.peg.1942 627 627 yes 1890996 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 575540 Isosphaera pallida ATCC 43644 Bacteria UP000008631 319749710 ADV61470.1 fig|575540.3.peg.1128 466 476 yes 1890997 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 28892 Methanofollis liminatans DSM 4140 Archaea UP000005095 395441329 EJG06086.1 J0RX33 J0RX33_9EURY 414 426 no 1890998 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053218, 1053219 Bacillus cereus, Bacillus cereus MC118, Bacillus cereus MC67 Bacteria UP000036076, UP000014025, UP000006997 488088450, 500399409, 401193627 EOP15302.1, EJR00632.1 WP_002159847.1 fig|1053219.3.peg.2506, fig|1053218.3.peg.2590 586 586 yes 1890999 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 119858, 1274524 Bacillus sonorensis, Bacillus sonorensis L12 Bacteria UP000011907 493686448, 452976013 EME75829.1 WP_006636549.1 fig|1274524.3.peg.564 591 591 yes 1891000 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 380358 Xanthomonas albilineans GPE PC73 Bacteria UP000001890 283472774 fig|29447.3.peg.761 624 627 yes 1891001 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 873, 1262666 Desulfovibrio africanus, Desulfovibrio africanus PCS Bacteria UP000011922 492834130, 459315451 EMG36228.1 WP_005988084.1 fig|1262666.3.peg.2760 418 424 no 1891002 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570, 1125630, 573, 571, 72407, 1409965, 1328325, 1087440, 1225181, 1284827, 1284790, 1284819, 1284814, 1304917, 1400170, 1094170, 1438810, 1438808, 1438806, 1438804, 1438802, 1438800, 1438796, 1438792, 1438794, 1438790, 1438784, 1438782, 1438783, 1438781, 1438780, 1438779, 1438778, 1438777, 1438775, 1438776, 1438774, 1438773, 1438771, 1438770, 1438768, 1438769, 1438767, 1438765, 1438764, 1438763, 1438762, 1438761, 1438760, 1438759, 1438758, 1438757, 1438756, 1438755, 1438752, 1438750, 1438751, 1438747, 1438746, 1438745, 1438744, 1438743, 1438742, 1438741, 1438740, 1438739, 1438738, 1438737, 1438736, 1438735, 1438733, 1438734, 1438732, 1438731, 1438730, 1438729, 1438728, 1438726, 1438725, 1438723, 1438724, 1438720, 1438719, 1438717, 1438718, 1438715, 1438713, 1438712, 1438711, 1438709, 1438708, 1438705, 1438703, 1438701, 1438699, 1438698, 1328413, 1438714, 1438722, 1438748, 1438753, 1438766, 1310158, 1310159, 1420012, 1420013, 1328396, 1328367, 1328369, 1328377, 1328383, 1328389, 1328387, 1328398, 1328406, 1328407, 1328410, 1328412, 1328423, 1400162, 1400172, 1400175, 1400174, 1400178, 1400181, 1400182, 1400185, 1400184, 1263871, 1328408, 1328414, 1380908, 1341693, 1343063, 1304919, 1304916, 1304918, 1284792, 1284809, 1284808, 1284807, 1284806, 1284805, 1284804, 1284803, 1284802, 1284800, 1284799, 1284798, 1284795, 1284794, 1284793, 1284789, 1284791, 1284822, 1284801, 1284821, 1284796, 1304924, 1304923, 1304922, 1304921, 1304920, 1284832, 1284831, 1284830, 1284829, 1284828, 1284826, 1284825, 1284820, 1284824, 1284823, 1284816, 1284813, 1284815, 1284811, 1284810, 1284787, 1284788, 1228988, 1276652, 1236102, 1168064, 1168063, 1168062, 1128953, 1128954, 1128952, 1128950, 1128951, 1128948, 1128946, 1094171, 1094168, 1094169, 1094167, 1087444, 1087445, 1087443, 1087441, 1432550, 1432560, 1185418, 1185420, 1185419 Klebsiella pneumoniae subsp. pneumoniae HS11286, Klebsiella pneumoniae, Klebsiella oxytoca, Klebsiella pneumoniae subsp. pneumoniae, Klebsiella pneumoniae MRSN 6902, Klebsiella pneumoniae subsp. pneumoniae KPNIH28, Klebsiella pneumoniae subsp. pneumoniae KPNIH1, Klebsiella pneumoniae subsp. pneumoniae KPNIH24, Klebsiella pneumoniae VAKPC278, Klebsiella pneumoniae UHKPC05, Klebsiella pneumoniae UHKPC45, Klebsiella pneumoniae UHKPC 52, Klebsiella pneumoniae 160_1080, Klebsiella pneumoniae UCI 17, Klebsiella pneumoniae subsp. pneumoniae KPNIH10, Klebsiella pneumoniae UCI 67, Klebsiella pneumoniae UCI 63, Klebsiella pneumoniae UCI 61, Klebsiella pneumoniae UCI 59, Klebsiella pneumoniae UCI 55, Klebsiella pneumoniae MGH-79, Klebsiella pneumoniae MGH-73, Klebsiella pneumoniae MGH-69, Klebsiella pneumoniae MGH-71, Klebsiella pneumoniae MGH-67, Klebsiella pneumoniae MGH 59, Klebsiella pneumoniae MGH 51, Klebsiella pneumoniae MGH 52, Klebsiella pneumoniae CHS 80, Klebsiella pneumoniae CHS 76, Klebsiella pneumoniae CHS 75, Klebsiella pneumoniae CHS 74, Klebsiella pneumoniae CHS 73, Klebsiella pneumoniae CHS 71, Klebsiella pneumoniae CHS 72, Klebsiella pneumoniae CHS 70, Klebsiella pneumoniae CHS 67, Klebsiella pneumoniae CHS 65, Klebsiella pneumoniae CHS 64, Klebsiella pneumoniae CHS 62, Klebsiella pneumoniae CHS 63, Klebsiella pneumoniae CHS 61, Klebsiella pneumoniae CHS 59, Klebsiella pneumoniae CHS 58, Klebsiella pneumoniae CHS 57, Klebsiella pneumoniae CHS 56, Klebsiella pneumoniae CHS 55, Klebsiella pneumoniae CHS 54, Klebsiella pneumoniae CHS 53, Klebsiella pneumoniae CHS 52, Klebsiella pneumoniae CHS 51, Klebsiella pneumoniae CHS 50, Klebsiella pneumoniae CHS 49, Klebsiella pneumoniae CHS 46, Klebsiella pneumoniae CHS 44, Klebsiella pneumoniae CHS 45, Klebsiella pneumoniae CHS 41, Klebsiella pneumoniae CHS 40, Klebsiella pneumoniae CHS 39, Klebsiella pneumoniae CHS 38, Klebsiella pneumoniae CHS 37, Klebsiella pneumoniae CHS 36, Klebsiella pneumoniae CHS 35, Klebsiella pneumoniae CHS 34, Klebsiella pneumoniae CHS 33, Klebsiella pneumoniae CHS 32, Klebsiella pneumoniae CHS 31, Klebsiella pneumoniae CHS 30, Klebsiella pneumoniae CHS 29, Klebsiella pneumoniae CHS 27, Klebsiella pneumoniae CHS 28, Klebsiella pneumoniae CHS 26, Klebsiella pneumoniae CHS 25, Klebsiella pneumoniae CHS 24, Klebsiella pneumoniae CHS 23, Klebsiella pneumoniae CHS 22, Klebsiella pneumoniae CHS 20, Klebsiella pneumoniae CHS 19, Klebsiella pneumoniae CHS 17, Klebsiella pneumoniae CHS 18, Klebsiella pneumoniae CHS 14, Klebsiella pneumoniae CHS 13, Klebsiella pneumoniae CHS 11, Klebsiella pneumoniae CHS 12, Klebsiella pneumoniae CHS 09, Klebsiella pneumoniae CHS 07, Klebsiella pneumoniae CHS 06, Klebsiella pneumoniae CHS 05, Klebsiella pneumoniae CHS 03, Klebsiella pneumoniae CHS 02, Klebsiella pneumoniae BWH 47, Klebsiella pneumoniae BWH 45, Klebsiella pneumoniae BIDMC 68, Klebsiella pneumoniae BIDMC 60, Klebsiella pneumoniae BIDMC 55, Klebsiella pneumoniae BIDMC 18B, Klebsiella pneumoniae CHS 08, Klebsiella pneumoniae CHS 16, Klebsiella pneumoniae CHS 42, Klebsiella pneumoniae CHS 47, Klebsiella pneumoniae CHS 60, Klebsiella pneumoniae Kb140, Klebsiella pneumoniae Kb677, Klebsiella pneumoniae 30660/NJST258_1, Klebsiella pneumoniae 30684/NJST258_2, Klebsiella pneumoniae UCICRE 13, Klebsiella pneumoniae MGH 29, Klebsiella pneumoniae MGH 31, Klebsiella pneumoniae MGH 45, Klebsiella pneumoniae BWH 22, Klebsiella pneumoniae UCICRE 1, Klebsiella pneumoniae BWH 41, Klebsiella pneumoniae BIDMC 1, Klebsiella pneumoniae BIDMC 12A, Klebsiella pneumoniae BIDMC 12B, Klebsiella pneumoniae BIDMC 14, Klebsiella pneumoniae BIDMC 18A, Klebsiella pneumoniae BIDMC 34, Klebsiella pneumoniae BIDMC 45, Klebsiella pneumoniae UCI 19, Klebsiella pneumoniae UCI 22, Klebsiella pneumoniae UCI 21, Klebsiella pneumoniae UCI 33, Klebsiella pneumoniae UCI 38, Klebsiella pneumoniae UCI 41, Klebsiella pneumoniae UCI 44, Klebsiella pneumoniae UCI 43, Klebsiella pneumoniae ATCC BAA-2146, Klebsiella pneumoniae BIDMC 12C, Klebsiella pneumoniae BIDMC 18C, Klebsiella pneumoniae JM45, Klebsiella pneumoniae subsp. pneumoniae MP14, Klebsiella pneumoniae subsp. pneumoniae UKKV901664, Klebsiella pneumoniae 280_1220, Klebsiella pneumoniae 140_1040, Klebsiella pneumoniae 120_1020, Klebsiella pneumoniae UHKPC67, Klebsiella pneumoniae UHKPC02, Klebsiella pneumoniae UHKPC06, Klebsiella pneumoniae UHKPC31, Klebsiella pneumoniae UHKPC18, Klebsiella pneumoniae UHKPC17, Klebsiella pneumoniae UHKPC07, Klebsiella pneumoniae UHKPC59, Klebsiella pneumoniae UHKPC33, Klebsiella pneumoniae UHKPC61, Klebsiella pneumoniae DMC1316, Klebsiella pneumoniae DMC1097, Klebsiella pneumoniae UHKPC96, Klebsiella pneumoniae UHKPC77, Klebsiella pneumoniae UHKPC69, Klebsiella pneumoniae UHKPC28, Klebsiella pneumoniae UHKPC47, Klebsiella pneumoniae UHKPC32, Klebsiella pneumoniae UHKPC48, Klebsiella pneumoniae UHKPC29, Klebsiella pneumoniae DMC0526, Klebsiella pneumoniae 646_1568, Klebsiella pneumoniae 540_1460, Klebsiella pneumoniae 500_1420, Klebsiella pneumoniae 440_1540, Klebsiella pneumoniae 361_1301, Klebsiella pneumoniae VAKPC309, Klebsiella pneumoniae VAKPC297, Klebsiella pneumoniae VAKPC276, Klebsiella pneumoniae VAKPC270, Klebsiella pneumoniae VAKPC280, Klebsiella pneumoniae VAKPC269, Klebsiella pneumoniae VAKPC254, Klebsiella pneumoniae UHKPC22, Klebsiella pneumoniae VAKPC252, Klebsiella pneumoniae UHKPC04, Klebsiella pneumoniae UHKPC26, Klebsiella pneumoniae UHKPC27, Klebsiella pneumoniae UHKPC24, Klebsiella pneumoniae UHKPC01, Klebsiella pneumoniae UHKPC09, Klebsiella pneumoniae UHKPC40, Klebsiella pneumoniae UHKPC23, Klebsiella pneumoniae subsp. pneumoniae KpMDU1, Klebsiella pneumoniae ATCC BAA-1705, Klebsiella pneumoniae VA360, Klebsiella pneumoniae subsp. pneumoniae KPNIH23, Klebsiella pneumoniae subsp. pneumoniae KPNIH22, Klebsiella pneumoniae subsp. pneumoniae KPNIH21, Klebsiella pneumoniae subsp. pneumoniae KPNIH19, Klebsiella pneumoniae subsp. pneumoniae KPNIH20, Klebsiella pneumoniae subsp. pneumoniae KPNIH18, Klebsiella pneumoniae subsp. pneumoniae KPNIH16, Klebsiella pneumoniae subsp. pneumoniae KPNIH17, Klebsiella pneumoniae subsp. pneumoniae KPNIH14, Klebsiella pneumoniae subsp. pneumoniae KPNIH12, Klebsiella pneumoniae subsp. pneumoniae KPNIH11, Klebsiella pneumoniae subsp. pneumoniae KPNIH8, Klebsiella pneumoniae subsp. pneumoniae KPNIH9, Klebsiella pneumoniae subsp. pneumoniae KPNIH7, Klebsiella pneumoniae subsp. pneumoniae KPNIH5, Klebsiella pneumoniae subsp. pneumoniae KPNIH6, Klebsiella pneumoniae subsp. pneumoniae KPNIH4, Klebsiella pneumoniae subsp. pneumoniae KPNIH2, Klebsiella pneumoniae IS33, Escherichia coli ISC56, Klebsiella pneumoniae subsp. pneumoniae ST512-K30BO, Klebsiella pneumoniae subsp. pneumoniae ST258-K28BO, Klebsiella pneumoniae subsp. pneumoniae ST258-K26BO Bacteria UP000007841, UP000036212, UP000030350, UP000060052, UP000034622, UP000027427, UP000006499, UP000027423, UP000028373, UP000027829, UP000014300, UP000014299, UP000028208, UP000027786, UP000006475, UP000027053, UP000027298, UP000027500, UP000027565, UP000027315, UP000027566, UP000027531, UP000027326, UP000027505, UP000027553, UP000027524, UP000027266, UP000027577, UP000027176, UP000027212, UP000027339, UP000027512, UP000027297, UP000027278, UP000027167, UP000027113, UP000027347, UP000027509, UP000027255, UP000027001, UP000027444, UP000027501, UP000027259, UP000027061, UP000027541, UP000027032, UP000027198, UP000027055, UP000027029, UP000027355, UP000027574, UP000027569, UP000027283, UP000027211, UP000027520, UP000027299, UP000027169, UP000027534, UP000027282, UP000027548, UP000027532, UP000027162, UP000027460, UP000027099, UP000027561, UP000027335, UP000027175, UP000027203, UP000027528, UP000027269, UP000027513, UP000027258, UP000027041, UP000027522, UP000027263, UP000027516, UP000027554, UP000027517, UP000027008, UP000027529, UP000027550, UP000027525, UP000027168, UP000027028, UP000027104, UP000027209, UP000027523, UP000027575, UP000027151, UP000027578, UP000027518, UP000027270, UP000027576, UP000027137, UP000027571, UP000027572, UP000026269, UP000024634, UP000024029, UP000023868, UP000024057, UP000019659, UP000019654, UP000019583, UP000019586, UP000022934, UP000023012, UP000020774, UP000020958, UP000021696, UP000022621, UP000022716, UP000023497, UP000022786, UP000021399, UP000023335, UP000021419, UP000021231, UP000021861, UP000023343, UP000020531, UP000022708, UP000020838, UP000021006, UP000020118, UP000020220, UP000020093, UP000012013, UP000017147, UP000017153, UP000015544, UP000015060, UP000015747, UP000014866, UP000014846, UP000014829, UP000014839, UP000014849, UP000014851, UP000014828, UP000014859, UP000014872, UP000014863, UP000014820, UP000014853, UP000014884, UP000014825, UP000014838, UP000014832, UP000014833, UP000014873, UP000014840, UP000014834, UP000014308, UP000014255, UP000014248, UP000014250, UP000014277, UP000014312, UP000014275, UP000014282, UP000014298, UP000014311, UP000014289, UP000014272, UP000014273, UP000014297, UP000014304, UP000014267, UP000014256, UP000014284, UP000014291, UP000014302, UP000014251, UP000014260, UP000014271, UP000014309, UP000014283, UP000014031, UP000013110, UP000011998, UP000012147, UP000006472, UP000009018, UP000009030, UP000006476, UP000009041, UP000009034, UP000006493, UP000006484, UP000006485, UP000009040, UP000006498, UP000006489, UP000006486, UP000009031, UP000009042, UP000006487, UP000006495, UP000009021, UP000019200, UP000019186, UP000009314, UP000009322, UP000009329 488973398, 378976372, 839830589, 839800976, 839799018, 839790577, 839770511, 839714830, 839639599, 839633556, 839602028, 839566984, 839561465, 839560712, 839553108, 839544962, 839542727, 839534419, 839534044, 839526083, 839518208, 839512201, 839511688, 839504892, 839498043, 839493961, 839480259, 839477700, 839476846, 839474430, 839464025, 839463785, 839454659, 839448703, 839444118, 839434888, 839431052, 839426930, 839423711, 839408981, 839403414, 839394496, 839378512, 839374010, 839373841, 839364362, 839361631, 839361346, 839350361, 839343528, 839340876, 839325125, 839324317, 839321165, 839313584, 839309140, 839308822, 839297267, 839290267, 839277157, 839276779, 839276201, 839270094, 839260896, 839255730, 839250842, 839245024, 839223010, 839218728, 839213441, 839201382, 839200017, 839196374, 839186037, 839185866, 839180600, 839172118, 839162521, 839161728, 839146092, 839137167, 839133570, 839128677, 839111967, 839111244, 839108033, 839103408, 839100270, 839085885, 839084229, 839082577, 839072713, 839067843, 839067344, 839055505, 839055459, 839045496, 839038941, 839026510, 839025623, 839022888, 839011264, 839007269, 838994720, 838993928, 838985308, 838977069, 838968921, 838965835, 838959483, 838957857, 838949153, 838944692, 838937068, 838935753, 838928742, 838914480, 838912100, 838911847, 838907620, 838901405, 838895701, 838890024, 838884799, 838876550, 838870915, 838862889, 838860838, 838854686, 838840403, 838835242, 828973164, 828909666, 821674190, 816078307, 743008546, 742999101, 736289645, 736281337, 727665072, 723244274, 717154189, 717144531, 672218402, 672218095, 668911632, 662226583, 661927624, 661922223, 660577361, 657276921, 656944599, 656940425, 656933886, 656929372, 656922615, 655429350, 640845469, 636460585, 636458125, 636446381, 636436243, 636425857, 636418324, 636402058, 636388279, 636387359, 636369270, 636349156, 636338263, 636335007, 636332607, 636324719, 636316429, 636316393, 636312171, 636305218, 636299972, 636295481, 636286735, 636276158, 636275636, 636263079, 636262624, 636254219, 636248927, 636243582, 636238619, 636233267, 636227182, 636218559, 636215913, 636211447, 636206090, 636201978, 636190586, 636186384, 636179700, 636170878, 636160816, 636154337, 636153494, 636141226, 636136571, 636134578, 636120498, 636120462, 636118326, 636111947, 636101785, 636101643, 636090855, 636088317, 636087686, 636075607, 636069193, 636067379, 636061417, 636050494, 636048175, 636043382, 636039588, 636035925, 636026588, 636023289, 636012906, 636010701, 636005549, 636000004, 635995825, 635984430, 635982245, 635981974, 635969021, 635959002, 635942000, 635936766, 635925458, 635921370, 617121832, 612309505, 612300743, 612289035, 612283464, 597728235, 597722666, 595630829, 595620458, 583738018, 583722363, 583721849, 583693168, 583666498, 583658759, 583654957, 583647198, 583614270, 583608303, 583601417, 583586644, 583577003, 583523632, 583512393, 583494016, 583492934, 583479670, 583459942, 583457866, 583449252, 583445670, 582030386, 550197859, 550191782, 530347272, 525534937, 525532335, 519564394, 519557366, 519555467, 519542004, 519533623, 519531990, 519527382, 519517087, 519510873, 519505063, 519502722, 519497185, 519489361, 519487320, 519483969, 519470429, 519459507, 519454976, 519448863, 519443086, 519438677, 510359243, 510358344, 510350229, 510344633, 510340994, 510333847, 510325952, 510325445, 509719159, 509708280, 509699059, 509693953, 509685059, 509683860, 509669096, 509664232, 509660756, 509653558, 509647718, 509640674, 509631941, 509628998, 509627090, 509622664, 509619952, 509618124, 509606335, 509603549, 509575899, 507126381, 480518464, 471251237, 471239355, 460780454, 397449484, 397442663, 397435891, 397427789, 397426285, 397419735, 397409156, 397409070, 397401838, 397392820, 397391692, 397376938, 397373967, 397361679, 397357811, 397357670, 397342951, 397340631, 364515783, 758066049, 699969495, 572159991, 571156846, 427539621, 410123023, 410115496 KMJ03012.1, KMI73625.1, KMI71685.1, KMI63304.1, KMI43382.1, KMH88271.1, KMH14220.1, KMH08222.1, KMG77073.1, KMG42441.1, KMG36975.1, KMG36236.1, KMG28680.1, KMG20598.1, KMG18385.1, KMG10120.1, KMG09755.1, KMG01846.1, KMF94032.1, KMF88042.1, KMF87534.1, KMF80805.1, KMF74005.1, KMF69965.1, KMF56391.1, KMF53855.1, KMF53025.1, KMF50640.1, KMF40335.1, KMF40098.1, KMF31083.1, KMF25199.1, KMF20661.1, KMF11479.1, KMF07682.1, KMF03606.1, KMF00413.1, KME85812.1, KME80296.1, KME71452.1, KME55658.1, KME51223.1, KME51060.1, KME41640.1, KME38957.1, KME38678.1, KME27795.1, KME21015.1, KME18384.1, KME02769.1, KME01978.1, KMD98858.1, KMD91333.1, KMD86934.1, KMD86617.1, KMD75191.1, KMD68255.1, KMD55236.1, KMD54860.1, KMD54285.1, KMD48273.1, KMD39113.1, KMD34014.1, KMD29191.1, KMD23416.1, KMD01625.1, KMB97409.1, KMB92195.1, KMB80239.1, KMB78893.1, KMB75301.1, KMB65044.1, KMB64880.1, KMB59657.1, KMB51264.1, KMB41746.1, KMB40967.1, KMB25530.1, KMB16669.1, KMB13108.1, KMB08275.1, KMA91700.1, KMA90990.1, KMA87824.1, KMA83235.1, KMA80117.1, KMA65838.1, KMA64196.1, KMA62563.1, KMA52774.1, KMA47951.1, KMA47466.1, KMA35719.1, KMA35676.1, KMA25815.1, KMA19315.1, KMA06994.1, KMA06120.1, KMA03400.1, KLZ91853.1, KLZ87909.1, KLZ75461.1, KLZ74695.1, KLZ66124.1, KLZ57943.1, KLZ49854.1, KLZ46800.1, KLZ40501.1, KLZ38877.1, KLZ30251.1, KLZ25847.1, KLZ18267.1, KLZ16971.1, KLZ10043.1, KLY95878.1, KLY93517.1, KLY93272.1, KLY89085.1, KLY82942.1, KLY77278.1, KLY71660.1, KLY66464.1, KLY58295.1, KLY52696.1, KLY44743.1, KLY42719.1, KLY36626.1, KLY22438.1, KLY17325.1, AKL45908.1, AKK88114.1, KLA42320.1, KKJ25932.1, AJB59978.1, AJB78431.1, KHQ45692.1, KHQ36946.1, KHF60351.1, AIX76902.1, AIW74376.1, AIW68831.1, KFG15599.1, KFG15307.1, KFC45072.1, KEP95132.1, AIE26287.1, AIE20890.1, AID93867.1, KEG33513.1, KEF87999.1, KEF83835.1, KEF77302.1, KEF72789.1, KEF66033.1, KEC99533.1, AIA34577.1, KDM37126.1, KDM34693.1, KDM23073.1, KDM13020.1, KDM02721.1, KDL95289.1, KDL79155.1, KDL65447.1, KDL64535.1, KDL46608.1, KDL26652.1, KDL15836.1, KDL12609.1, KDL10236.1, KDL02373.1, KDK94119.1, KDK94084.1, KDK89908.1, KDK82979.1, KDK77748.1, KDK73287.1, KDK64578.1, KDK54060.1, KDK53540.1, KDK41038.1, KDK40584.1, KDK32212.1, KDK26937.1, KDK21613.1, KDK16686.1, KDK11358.1, KDK05325.1, KDJ96745.1, KDJ94134.1, KDJ89701.1, KDJ84367.1, KDJ80288.1, KDJ68951.1, KDJ64767.1, KDJ58135.1, KDJ49345.1, KDJ39367.1, KDJ32836.1, KDJ32073.1, KDJ19888.1, KDJ15257.1, KDJ13277.1, KDI99268.1, KDI99233.1, KDI97129.1, KDI90800.1, KDI80675.1, KDI80537.1, KDI69825.1, KDI67292.1, KDI66663.1, KDI54677.1, KDI48277.1, KDI46507.1, KDI40582.1, KDI29728.1, KDI27432.1, KDI22660.1, KDI18890.1, KDI15253.1, KDI06033.1, KDI02761.1, KDH92467.1, KDH90277.1, KDH85435.1, KDH79914.1, KDH75763.1, KDH64402.1, KDH62223.1, KDH61956.1, KDH49116.1, KDH39146.1, KDH22249.1, KDH17046.1, KDH05795.1, KDH01733.1, KAI86514.1, EZR02114.1, EZQ93521.1, EZQ82126.1, EZQ76651.1, EYB78389.1, EYB72821.1, AHM87617.1, AHM77215.1, EWF99831.1, EWF84327.1, EWF83816.1, EWF55389.1, EWF28930.1, EWF21239.1, EWF17460.1, EWF09753.1, EWE77075.1, EWE71151.1, EWE64324.1, EWE49701.1, EWE40154.1, EWD87189.1, EWD76058.1, EWD57791.1, EWD56718.1, EWD43562.1, EWD23985.1, EWD21938.1, EWD14470.1, EWD09852.1, AHI33720.1, ERO88446.1, ERO82510.1, AGT26505.1, EPS06538.1, EPS04176.1, EPP09895.1, EPP03398.1, EPP01622.1, EPO88852.1, EPO80914.1, EPO79391.1, EPO75022.1, EPO65189.1, EPO59344.1, EPO53834.1, EPO51666.1, EPO46409.1, EPO38985.1, EPO37067.1, EPO33983.1, EPO21177.1, EPO10785.1, EPO06537.1, EPO00807.1, EPN95341.1, EPN91163.1, EPB37248.1, EPB36446.1, EPB28775.1, EPB23465.1, EPB20003.1, EPB13329.1, EPB05944.1, EPB05461.1, EPA02855.1, EOZ92563.1, EOZ79889.1, EOZ74236.1, EOZ65806.1, EOZ64658.1, EOZ50679.1, EOZ46091.1, EOZ42733.1, EOZ35869.1, EOZ30283.1, EOZ23536.1, EOZ15263.1, EOZ12471.1, EOZ10637.1, EOZ06479.1, EOZ03899.1, EOZ02191.1, EOY90988.1, EOY88310.1, EOY69059.1, EOR19270.1, ENY59522.1, EMR28565.1, EMR16813.1, EMI37022.1, EJK39618.1, EJK33009.1, EJK26494.1, EJK18549.1, EJK17115.1, EJK10863.1, EJK00482.1, EJK00400.1, EJJ93455.1, EJJ84597.1, EJJ83523.1, EJJ69183.1, EJJ66336.1, EJJ54338.1, EJJ50551.1, EJJ50416.1, EJJ36104.1, EJJ33829.1, AEW58911.1 WP_002884310.1, YP_005224513.1 fig|1284815.3.peg.806, fig|1284826.3.peg.3062, fig|1094170.3.peg.4780, fig|1236102.6.peg.2307, fig|1128946.3.peg.4956, fig|1094168.3.peg.4737, fig|1284790.3.peg.809, fig|1276652.3.peg.2658, fig|1284801.3.peg.2558, fig|1304923.3.peg.1994, fig|1284829.3.peg.3184, fig|1185420.3.peg.754, fig|1284831.3.peg.3082, fig|1284830.3.peg.3168, fig|1284828.3.peg.3115, fig|1284832.3.peg.1643, fig|1128953.3.peg.4681, fig|1087441.3.peg.4942, fig|1284825.3.peg.4151, fig|1284824.3.peg.4936, fig|1284823.3.peg.2981, fig|1284819.3.peg.3508, fig|1304924.3.peg.921, fig|404589.10.peg.4132, fig|1168064.3.peg.4155, fig|1128950.3.peg.4913, fig|1284811.3.peg.159, fig|1128951.3.peg.4932, fig|1284822.3.peg.4259, fig|1284814.3.peg.3197, fig|1128948.3.peg.4821, fig|1094167.3.peg.4920, fig|1185418.3.peg.2631, fig|1168063.3.peg.4797, fig|1304922.3.peg.3074, fig|1284788.3.peg.471, fig|1284813.3.peg.682, fig|1284816.3.peg.871, fig|1284821.3.peg.1618, fig|1087445.3.peg.4849, fig|1125630.4.peg.210, fig|1128954.3.peg.4885, fig|1263871.3.peg.4855, fig|1304920.3.peg.2158, fig|1284827.3.peg.1653, fig|1128952.3.peg.4981, fig|1284810.3.peg.505, fig|1087440.3.peg.4958, fig|1212766.3.peg.3832, fig|1094169.3.peg.4974, fig|1284787.3.peg.3863, fig|1087444.3.peg.4750, fig|1284820.3.peg.2186, fig|1087443.3.peg.4643, fig|1094171.3.peg.4808, fig|1185419.3.peg.2467, fig|1168062.3.peg.4830, fig|1284796.3.peg.5002 626 631 yes 1891003 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1412544 Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120505 Bacteria UP000023712 603653976 AHS24111.1 347 350 no 1891004 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1235457 Ralstonia sp. AU12-08 Bacteria UP000015343 544771726, 528184422 EPX95362.1 WP_021197003.1 629 631 yes 1891005 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1007654 Bacillus sp. 916 Bacteria UP000005157 494650465, 393806887 EJD68218.1 WP_007408409.1 fig|1007654.3.peg.1479 590 590 yes 1891006 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36809 Mycobacterium abscessus Bacteria UP000046141 515405499 WP_016894595.1 545 546 yes 1891007 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 475067, 1107882 Mesorhizobium alhagi, Mesorhizobium alhagi CCNWXJ12-2 Bacteria UP000003250 496114248, 359250880 EHK54308.1 WP_008838755.1 fig|1107882.3.peg.5018 597 603 yes 1891008 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1404, 1348623 Bacillus megaterium, Bacillus megaterium NBRC 15308 Bacteria UP000036135, UP000029853 515134091, 753728773, 694294713, 675490803 AJI24542.1, KGJ73432.1, KFN08486.1 WP_016762883.1 589 589 yes 1891009 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 100053, 1049759 Leptospira alexanderi, Leptospira alexanderi serovar Manhao 3 str. L 60 Bacteria UP000018747 498262870, 529327950 EQA64570.1 WP_010577026.1 519 521 yes 1891010 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 113287, 887929 Pseudoramibacter alactolyticus, Pseudoramibacter alactolyticus ATCC 23263 Bacteria UP000004754 493647254, 315621546 EFV01511.1 WP_006598854.1 436 437 yes 1891011 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1757, 509192 Thermoanaerobacter ethanolicus, Thermoanaerobacter ethanolicus JW 200 Bacteria UP000003220 489967976, 325992247 EGD50715.1 WP_003871220.1 431 432 yes 1891012 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 498055, 1121015 Arenimonas oryziterrae, Arenimonas oryziterrae DSM 21050 Bacteria UP000029385 551351048, 675590704 KFN42456.1 WP_022970429.1 625 626 yes 1891013 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1007084, 859192 Candidatus Nitrosoarchaeum limnia, marine archaeal group 1 strain BG20 Archaea 497878779, 509753140 EPA05187.1 WP_010192935.1 S2EKK6 S2EKK6_9ARCH 440 440 yes 1891014 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1290, 904339, 435837 Staphylococcus hominis, Staphylococcus epidermidis VCU122, Staphylococcus hominis subsp. hominis C80 Bacteria UP000054429, UP000010129, UP000010143 488385265, 374823812, 313656655 EHR87804.1, EFS20394.1 WP_002454650.1 fig|435837.3.peg.206, fig|904339.3.peg.1190 580 580 yes 1891015 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324 Stenotrophomonas maltophilia Bacteria UP000034806 518491830 WP_019662037.1 613 614 yes 1891016 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44752, 1219028 Rhodococcus wratislaviensis, Rhodococcus wratislaviensis NBRC 100605 Bacteria UP000019491 739379819, 589256566 WP_037240613.1 541 548 yes 1891017 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1435036, 1217715 Acinetobacter sp. ANC 4253, Acinetobacter sp. ANC 3994 Bacteria UP000013086 490787885, 479866401 ENU18241.1 WP_004650043.1 fig|1217715.3.peg.3287 627 631 yes 1891018 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 32057 Calothrix sp. PCC 7103 Bacteria 518324431 WP_019494638.1 458 459 yes 1891019 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1165, 272123 Anabaena cylindrica, Anabaena cylindrica PCC 7122 Bacteria UP000010474 505026486, 428678171 AFZ56937.1 WP_015213588.1 fig|272123.3.peg.1559 455 457 yes 1891020 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204516 Bacteroides massiliensis Bacteria 517263922 WP_018452740.1 568 568 yes 1891021 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 455546 uncultured marine microorganism HF4000_APKG2J17 Environmental samples 167043520 ABZ08216.1 601 623 yes 1891022 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 610 629 yes 1891023 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 511062 Oceanimonas sp. GK1 Bacteria UP000007742 372983844 AEY00094.1 fig|511062.4.peg.337 642 651 yes 1891024 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76891, 715226 Asticcacaulis biprosthecium, Asticcacaulis biprosthecum C19 Bacteria UP000006512 493317938, 328839608 EGF89181.1 WP_006275302.1 610 613 yes 1891025 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 603 610 yes 1891026 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34058 Methylobacter marinus Bacteria 519003459 WP_020159334.1 621 622 yes 1891027 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1390, 1150476 Bacillus amyloliquefaciens, Bacillus amyloliquefaciens subsp. plantarum UCMB5113 Bacteria UP000027101, UP000015482 530665231, 530336663 WP_020955537.1 590 590 yes 1891028 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 797299 Halostagnicola larsenii XH-48 Archaea UP000019024 573480388 AHF98798.1 W0JJN5 W0JJN5_9EURY 474 498 yes 1891029 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 1385938, 1385943 Bifidobacterium breve, Bifidobacterium breve 12L, Bifidobacterium breve 2L Bacteria UP000029049, UP000019326, UP000019284 644321488, 585126620, 584612931 AHJ15994.1, EWH42221.1 WP_025299937.1 638 918 yes 1891030 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 124285 Nocardiopsis xinjiangensis Bacteria 516202564 WP_017608360.1 551 555 yes 1891031 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1390, 1225788 Bacillus amyloliquefaciens, Bacillus amyloliquefaciens subsp. plantarum AS43.3 Bacteria UP000027101, UP000010484 505052336, 429485960 AFZ89884.1 WP_015239438.1 fig|1225788.3.peg.881 590 590 yes 1891032 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1295009 Methanomassiliicoccus sp. Mx1-Issoire Archaea UP000014070 509093143 AGN27161.1 R9TBV2 R9TBV2_9EURY 420 424 yes 1891033 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 420 421 yes 1891034 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 991991, 991946 Vibrio cholerae, Vibrio cholerae CP1035, Vibrio cholerae HE45 Bacteria UP000028983, UP000008360, UP000000704 445993241, 408628704, 395956627 EKL01431.1, EJH67220.1 WP_000071096.1 fig|991946.3.peg.218, fig|991991.3.peg.143 639 645 yes 1891035 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 443144 Geobacter sp. M21 Bacteria UP000002380 506319315, 251777329 ACT19910.1 WP_015839090.1 fig|443144.3.peg.3808 432 435 yes 1891036 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 101192, 867904 Methanomethylovorans hollandica, Methanomethylovorans hollandica DSM 15978 Archaea UP000010866 505138032, 435851913, 433662543 AGB49969.1 WP_015325134.1, YP_007313499.1 L0L128 L0L128_METHD 425 425 yes 1891037 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310603 Acinetobacter baumannii, Acinetobacter baumannii 1294596 Bacteria UP000028632, UP000023787 736677268, 588679057 EXF57261.1 WP_034683652.1 626 630 yes 1891038 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65700, 1044999 Erwinia tracheiphila, Erwinia tracheiphila PSU-1 Bacteria UP000033924, UP000014135 510817873, 809011113, 507921653 KKF36823.1, EOS94518.1 WP_016191409.1 fig|1044999.3.peg.3017 631 644 yes 1891039 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 210408, 765913 Thiorhodococcus drewsii, Thiorhodococcus drewsii AZ1 Bacteria UP000004200 494098127, 343923365 EGV34057.1 WP_007038928.1 fig|765913.3.peg.214 627 630 yes 1891040 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1169338 Escherichia coli, Escherichia coli KTE19 Bacteria UP000036210, UP000014208 510912402, 508286960 EOU59917.1 WP_016233710.1 fig|1169338.3.peg.3749 626 631 yes 1891041 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33035 Blautia producta Bacteria 517424201 WP_018595468.1 434 435 yes 1891042 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 262668, 1217649 Acinetobacter beijerinckii, Acinetobacter beijerinckii ANC 3835 Bacteria UP000018417 491192509, 480069687 ENW08493.1 WP_005050860.1 fig|1217649.3.peg.76 626 631 yes 1891043 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1182724 Escherichia coli, Escherichia coli KTE144 Bacteria UP000036210, UP000010600 486387498, 431396298 ELG79780.1 WP_001600817.1 fig|1182724.3.peg.3974 626 631 yes 1891044 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 110319 Nocardioides sp. CF8 Bacteria UP000015971 498533320, 490488741 EON25120.1 WP_010831821.1 554 559 yes 1891045 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 129337, 550542, 544556 Geobacillus sp. Y412MC52, Geobacillus sp. Y412MC61 Bacteria UP000002223, UP000008468 503288263, 317110380, 261375156 ADU92872.1, ACX77899.1 WP_013522924.1 fig|550542.3.peg.2370, fig|544556.5.peg.1293 562 562 yes 1891046 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 250, 525257 Chryseobacterium gleum, Chryseobacterium gleum ATCC 35910 Bacteria UP000002969 489073891, 300506081 EFK37217.1 WP_002983846.1 603 603 yes 1891047 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 57029, 313595 Psychroflexus torquis, Psychroflexus torquis ATCC 700755 Bacteria UP000008514 504838992, 408470219 AFU70563.1 WP_015026094.1 619 619 yes 1891048 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262946 Roseburia sp. CAG:380 Environmental samples UP000017909 547901700, 524568491 WP_022305227.1 434 435 yes 1891049 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316 Pseudomonas stutzeri Bacteria UP000037382 518235216 WP_019405424.1 627 627 yes 1891050 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1400180 Klebsiella pneumoniae, Klebsiella pneumoniae UCI 37 Bacteria UP000036212, UP000023352 694087338, 583464372 EWD28391.1 WP_032432097.1 626 631 yes 1891051 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 159743, 985665 Paenibacillus terrae, Paenibacillus sp. HPL-003 Bacteria UP000032534, UP000005876 504045793, 357201159 AET59056.1 WP_014279787.1 fig|985665.3.peg.2269 593 595 yes 1891052 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 546, 1400136, 1432557 Citrobacter freundii, Citrobacter freundii UCI 31, Escherichia coli ISC11 Bacteria UP000030582, UP000023301, UP000019194 696376307, 838566589, 816226456, 763840815, 721544651, 575567360, 571187686 KLV51122.1, KKJ85310.1, KJC00697.1, KGY88004.1, ETX66953.1 WP_032950754.1 626 632 yes 1891053 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 296 Pseudomonas fragi Bacteria UP000065958 515154653 WP_016783276.1 627 629 yes 1891054 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59538 Pantholops hodgsonii Mammals 556747041 XP_005968980.1 575 583 yes 1891055 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2426 Teredinibacter turnerae Bacteria 517226721 WP_018415539.1 638 639 yes 1891056 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281258, 656440 Escherichia coli, Escherichia coli UMEA 3656-1, Escherichia coli TA206 Bacteria UP000036210, UP000016256, UP000003960 447199628, 535817029, 331052337 EQZ49552.1, EGI24375.1 WP_001276884.1 626 631 yes 1891057 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280663 Butyrivibrio sp. AE2015 Bacteria 551028940 WP_022773021.1 434 434 yes 1891058 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 621, 766141 Shigella boydii, Shigella boydii 5216-82 Bacteria UP000035613, UP000004081 447199627, 332083883 EGI89096.1 WP_001276883.1 fig|766141.3.peg.4661 626 631 yes 1891059 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 621, 932676 Shigella boydii, Shigella boydii ATCC 9905 Bacteria UP000035613, UP000004589 447199625, 320179543 EFW54494.1 WP_001276881.1 fig|621.8.peg.25, fig|932676.3.peg.3301 626 631 yes 1891060 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 620, 766138, 766142 Shigella boydii 965-58, Shigella dysenteriae 155-74 Bacteria UP000004209, UP000005200 447199624, 391264023, 332085399 EIQ23020.1, EGI90569.1 WP_001276880.1 fig|766138.3.peg.4891, fig|766142.3.peg.4403 626 631 yes 1891061 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116013 Escherichia coli, Escherichia coli 2762100 Bacteria UP000036210, UP000012310 492156374, 476232454 EMW51909.1 WP_005765950.1 fig|1116013.3.peg.4544 626 631 yes 1891062 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 377615, 717605 Thermobacillus composti, Thermobacillus composti KWC4 Bacteria UP000010795 505066965, 430733365 AGA57310.1 WP_015254067.1 587 588 yes 1891063 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 161879, 645127 Corynebacterium kroppenstedtii, Corynebacterium kroppenstedtii DSM 44385 Bacteria UP000001473 502206444, 237759180 ACR18430.1 WP_012732317.1 fig|645127.4.peg.1765 593 616 yes 1891064 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 411462 Dorea longicatena DSM 13814 Bacteria UP000004016 149751688 EDM61619.1 230 249 no 1891065 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1216932 Clostridium sp. M2/40 Bacteria UP000019426 584457259 437 437 yes 1891066 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1403344 Xylella fastidiosa Mul-MD Bacteria UP000019278 584118309 EWG14334.1 596 603 yes 1891067 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173940 Salmonella enterica, Salmonella enterica subsp. enterica serovar Worthington str. ATCC 9607 Bacteria UP000054489, UP000017551 554921815, 554064736 ESF08981.1 WP_023194459.1 626 631 yes 1891068 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 992010 Vibrio sp. HENC-01 Bacteria UP000008489 497382556, 408881566 EKM20442.1 WP_009696769.1 fig|992010.3.peg.1285 640 646 yes 1891069 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29483, 527002 Yersinia aldovae, Yersinia aldovae ATCC 35236 Bacteria UP000040411, UP000006231 490842627, 238701527 EEP94100.1 WP_004704699.1 fig|527002.3.peg.3565 652 677 yes 1891070 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1223565 Rhizobium sp. Pop5 Bacteria UP000006080 495805364, 403704168 EJZ20141.1 WP_008529943.1 292 297 yes 1891071 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1223565 Rhizobium sp. Pop5 Bacteria UP000006080 495805367, 403704158 EJZ20133.1 WP_008529946.1 306 306 no 1891072 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1089455 Mobilicoccus pelagius NBRC 104925 Bacteria UP000004367 377537441 fig|1089455.3.peg.1167 590 620 yes 1891073 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 50340 Pseudomonas fuscovaginae Bacteria UP000037883 498136264 WP_010450420.1 628 629 yes 1891074 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1264, 697329 Ruminococcus albus, Ruminococcus albus 7 Bacteria UP000006919 503264144, 315449084 ADU22648.1 WP_013498805.1 fig|697329.10.peg.2927 437 437 yes 1891075 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1429916 Afipia sp. Bat1 Bacteria UP000018975 736445514, 571922375 ETR78827.1 WP_034467390.1 624 633 yes 1891076 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168697 Salinispora arenicola Bacteria 517625794 WP_018796002.1 530 530 yes 1891077 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 70775, 1330531 Pseudomonas plecoglossicida, Pseudomonas plecoglossicida NB2011 Bacteria UP000031767, UP000014440 511762075, 511100663 EPB93597.1 WP_016395273.1 fig|1330531.3.peg.4420 627 628 yes 1891078 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144667 Acinetobacter sp. CIP 102159 Bacteria UP000023792 490894399, 479937132 ENU84079.1 WP_004756348.1 fig|1144667.3.peg.752 626 631 yes 1891079 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1204340 Pandoraea sp. B-6 Bacteria 515802082 WP_017232837.1 637 638 yes 1891080 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702, 682147 Gardnerella vaginalis, Gardnerella vaginalis AMD Bacteria UP000037770, UP000004317 490207938, 296888608 EFH27347.1 WP_004106346.1 608 876 yes 1891081 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 629773 Sphingomonas sp. Mn802worker Bacteria 518345216 WP_019515423.1 618 619 yes 1891082 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310640 Acinetobacter baumannii, Acinetobacter baumannii 342950 Bacteria UP000028632, UP000020455 691032841, 587914090 EXC01876.1 WP_031987869.1 621 625 yes 1891083 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 1339270 Bacteroides fragilis, Bacteroides fragilis str. I1345 Bacteria UP000036847, UP000022032 695480544, 596281909 EYB18753.1 WP_032573247.1 564 564 yes 1891084 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29329, 858215 Thermoanaerobacterium xylanolyticum, Thermoanaerobacterium xylanolyticum LX-11 Bacteria UP000007239 503554435, 333112840 AEF17777.1 WP_013788511.1 433 434 yes 1891085 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33995 Gluconacetobacter europaeus Bacteria UP000037566 498194062 WP_010508218.1 605 613 yes 1891086 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 654, 1347420 Aeromonas veronii, Aeromonas veronii Hm21 Bacteria UP000051545, UP000016378 544815007, 538454147 ERF62403.1 WP_021231605.1 645 663 yes 1891087 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 637 638 yes 1891088 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262963 Ruminococcus sp. CAG:579 Environmental samples UP000018387 547704276, 524315711 WP_022128043.1 437 437 yes 1891089 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 668, 1088719 Aliivibrio fischeri, Vibrio fischeri SR5 Bacteria UP000035964, UP000004521 491559235, 371495819 EHN71413.1 WP_005416821.1 fig|1088719.3.peg.34, fig|617135.3.peg.2816 640 644 yes 1891090 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1126, 721123 Microcystis aeruginosa, Microcystis aeruginosa PCC 9701 Bacteria UP000004047 490389406, 389882736 WP_004268861.1 fig|721123.3.peg.2323 457 460 yes 1891091 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43657, 1353533 Pseudoalteromonas luteoviolacea, Pseudoalteromonas luteoviolacea 2ta16 Bacteria UP000031327, UP000017820 557377183, 556909021 ESP94873.1 WP_023397740.1 645 650 yes 1891092 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 517307238 WP_018496056.1 598 605 yes 1891093 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615 Serratia marcescens Bacteria UP000055021 518286224 WP_019456432.1 632 647 yes 1891094 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1562, 868595 Desulfotomaculum carboxydivorans CO-1-SRB Bacteria UP000009226 503575558, 333748246 AEF93353.1 WP_013809634.1 fig|868595.4.peg.491 430 432 yes 1891095 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285091, 930169 Alcanivorax dieselolei, Alcanivorax dieselolei B5 Bacteria UP000050054, UP000006286 504805927, 407251840 AFT68947.1 WP_014993029.1 fig|930169.3.peg.646 623 625 yes 1891096 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173472, 1173471, 1182179, 1163747, 1173467 Salmonella enterica, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000236, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000235, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000754, Salmonella enterica subsp. enterica serovar Bareilly str. 2780, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000197 Bacteria UP000054489, UP000029181, UP000029161, UP000029171, UP000017381, UP000017475 446030549, 677760409, 677755490, 677720871, 554327757, 554323923 KFS82614.1, KFS77975.1, KFS45507.1, ESH64557.1, ESH60456.1 WP_000108404.1 626 631 yes 1891097 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1194149 Salmonella enterica, Salmonella enterica subsp. enterica serovar Hartford str. CFSAN001075 Bacteria UP000054489, UP000017367 446030548, 554458720 ESJ79708.1 WP_000108403.1 626 631 yes 1891098 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 187493, 1298593 Thalassolituus oleivorans, Thalassolituus oleivorans MIL-1 Bacteria UP000011866 505300123, 461492827 WP_015487225.1 fig|1298593.3.peg.2000 621 632 yes 1891099 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1248916 Sandarakinorhabdus sp. AAP62 Bacteria 516264631 WP_017668594.1 612 614 yes 1891100 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263022 Firmicutes bacterium CAG:424 Environmental samples UP000018167 547861258, 524505899 WP_022267890.1 313 314 yes 1891101 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 1439330, 1329856 Enterobacter cloacae, Enterobacter cloacae MGH 54, Enterobacter cloacae UCICRE 12 Bacteria UP000036177, UP000027551, UP000017344 556315495, 635773387, 555035086 KDF54839.1, ESL79415.1 WP_023294850.1 626 631 yes 1891102 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 382 Sinorhizobium meliloti Bacteria UP000028953 515835678 WP_017266431.1 600 611 yes 1891103 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 335659 Bradyrhizobium sp. S23321 Bacteria UP000007886 505721913, 381358039 WP_015684202.1 fig|335659.3.peg.1662 623 632 yes 1891104 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 64002 Nevskia ramosa Bacteria 551358999 WP_022978350.1 635 640 yes 1891105 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1053197, 1053199, 1053198 Bacillus cereus BtB2-4, Bacillus cereus CER074, Bacillus cereus CER057 Bacteria UP000003124, UP000006966, UP000006594 402430049, 401162832, 401149930 EJV62131.1, EJQ70185.1, EJQ57397.1 fig|1053246.3.peg.5167, fig|1053199.3.peg.343, fig|526997.3.peg.5472, fig|1053227.3.peg.327, fig|1053198.3.peg.5104, fig|1053197.3.peg.5103, fig|1053247.3.peg.368, fig|1053236.3.peg.5791, fig|1053248.3.peg.4533, fig|526972.3.peg.198 593 612 yes 1891106 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1056511 Photobacterium sp. AK15 Bacteria UP000011134 494735511, 441425804 ELR63297.1 WP_007470951.1 fig|1056511.3.peg.4710 637 641 yes 1891107 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 86170, 643648 Syntrophothermus lipocalidus, Syntrophothermus lipocalidus DSM 12680 Bacteria UP000000378 502939457, 297144274 ADI01031.1 WP_013174433.1 fig|643648.3.peg.258 425 425 yes 1891108 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144310 Rhizobium sp. CF080 Bacteria UP000007505 495047275, 576722549 EUC01126.1 WP_007772111.1 598 603 yes 1891109 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550984 Halomonas sp. HAL1 Bacteria UP000005692 496244278, 350599665 EHA15749.1 WP_008957663.1 fig|550984.5.peg.1706 633 633 yes 1891110 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1116369 Hoeflea sp. 108 Bacteria 517240940 WP_018429758.1 601 608 yes 1891111 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36809, 1185650, 319705, 1299321, 1335415, 1335412, 1335414, 1306401, 1303024, 1198627, 1001710, 1001709, 1001714, 1001712, 1001713, 1001711, 1001732, 1001707, 1001708, 1001706, 1001705, 1001704, 1001734, 1001733, 1001735, 1001730, 1001728, 1001729, 1001731, 1087483 Mycobacterium abscessus, Mycobacterium abscessus subsp. abcessus, Mycobacterium bolletii, Mycobacterium massiliense 1513, Mycobacterium abscessus MAB_091912_2455, Mycobacterium abscessus MAB_082312_2272, Mycobacterium abscessus MAB_091912_2446, Mycobacterium abscessus subsp. bolletii CRM-0020, Mycobacterium abscessus subsp. bolletii 50594, Mycobacterium massiliense str. GO 06, Mycobacterium massiliense 2B-0107, Mycobacterium massiliense 2B-1231, Mycobacterium massiliense CCUG 48898, Mycobacterium massiliense 2B-0912-S, Mycobacterium massiliense 2B-0307, Mycobacterium massiliense 2B-0912-R, Mycobacterium abscessus 5S-0921, Mycobacterium massiliense 1S-154-0310, Mycobacterium massiliense 2B-0626, Mycobacterium massiliense 1S-153-0915, Mycobacterium massiliense 1S-152-0914, Mycobacterium massiliense 1S-151-0930, Mycobacterium abscessus 5S-1215, Mycobacterium abscessus 5S-1212, Mycobacterium abscessus 5S-0817, Mycobacterium abscessus 5S-0708, Mycobacterium abscessus 5S-0304, Mycobacterium abscessus 5S-0421, Mycobacterium abscessus 5S-0422, Mycobacterium abscessus 47J26 Bacteria UP000046141, UP000030077, UP000030074, UP000023351, UP000023515, UP000022747, UP000018502, UP000014969, UP000013961, UP000009008, UP000002936, UP000005335, UP000002818, UP000003384, UP000002958, UP000005817, UP000004037, UP000005568, UP000005033, UP000003153, UP000004952, UP000003894, UP000003223, UP000003439, UP000004092, UP000005516, UP000006188, UP000005331, UP000003463, UP000003770 491203999, 701184618, 701180091, 690290106, 576473487, 576389766, 576384901, 560386116, 521564740, 506964452, 395458798, 392247747, 392245875, 392239905, 392192965, 392180066, 392178522, 392161398, 392154160, 392152760, 392148795, 392144022, 392138195, 392118475, 392104040, 392098866, 392096047, 392084043, 392082574, 392079048, 363994536, 353450293, 731179421 AIV19255.1, AIV14729.1, AIR41612.1, EUA67046.1, ETZ83792.1, ETZ78930.1, ESV65455.1, EPQ21695.1, AGM30833.1, AFN64461.1, EIV73223.1, EIV71352.1, EIV65398.1, EIV18589.1, EIV05718.1, EIV04175.1, EIU87088.1, EIU79866.1, EIU78467.1, EIU74513.1, EIU69747.1, EIU63932.1, EIU44243.1, EIU29826.1, EIU24660.1, EIU21842.1, EIU09868.1, EIU08400.1, EIU04875.1, EHM15757.1, EHB98688.1 WP_005062340.1 fig|1303024.3.peg.4327, fig|1001731.3.peg.4658, fig|1001709.3.peg.4053, fig|1001730.3.peg.3515, fig|1198627.3.peg.4101, fig|1001732.3.peg.4440, fig|1001714.3.peg.4212, fig|1162283.5.peg.1073, fig|1001710.3.peg.3350, fig|1001729.3.peg.3791, fig|1001728.3.peg.3538, fig|1162287.3.peg.466, fig|1087483.3.peg.3175, fig|1001708.3.peg.3989, fig|1001706.3.peg.3735, fig|1001712.3.peg.3992, fig|1001711.3.peg.4293, fig|1001734.3.peg.3536, fig|1001733.3.peg.3268, fig|1001735.3.peg.3139, fig|1001713.3.peg.3350, fig|1001704.3.peg.3364, fig|1001707.3.peg.3739, fig|1001705.3.peg.4388 545 546 yes 1891112 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1057002 Ensifer sp. Br816 Bacteria 517049874 WP_018238692.1 600 610 yes 1891113 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 134676 Actinoplanes sp. SE50/110 Bacteria UP000005440 504500691, 359833279 AEV81720.1 WP_014687793.1 fig|134676.3.peg.712 503 505 yes 1891114 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1156844 Streptomyces sp. HmicA12 Bacteria 517354185 WP_018529677.1 596 600 yes 1891115 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1461752 Sphingobium sp. Ant17 Bacteria UP000021537 759426898, 593811919 EXS71063.1 WP_043150143.1 653 664 yes 1891116 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1328417 Klebsiella pneumoniae, Klebsiella pneumoniae BIDMC 22 Bacteria UP000036212, UP000017586 556266544, 555015479 ESL59926.1 WP_023288121.1 626 631 yes 1891117 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81029, 1280949 Hyphomonas adhaerens, Hyphomonas adhaerens MHS-3 Bacteria UP000027446 737599253, 630938819 KCZ85156.1 WP_035569927.1 623 631 yes 1891118 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 698738 Oleispira antarctica RB-8 Bacteria UP000032749 508730807 638 641 yes 1891119 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 437897, 742816 Megamonas funiformis, Megamonas funiformis YIT 11815 Bacteria UP000005963 495815481, 374561169 EHR32517.1 WP_008540060.1 fig|742816.3.peg.2304 433 434 yes 1891120 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144342 Herbaspirillum sp. YR522 Bacteria UP000007507 495392752, 398214336 EJN00918.1 WP_008117453.1 fig|1144342.3.peg.3233 636 637 yes 1891121 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33903, 227882 Streptomyces avermitilis, Streptomyces avermitilis MA-4680 Bacteria UP000054019, UP000000428 499294434, 284867636, 47606149, 29607921 ADC10301.1 WP_010985692.1 Q82FI7 THIC_STRAW Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 227333 fig|227882.1.peg.4268 592 601 yes 1891122 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 658088 Lachnospiraceae bacterium 9_1_43BFAA Bacteria UP000003620 496557585, 330409191 EGG88642.1 WP_009263660.1 434 435 yes 1891123 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310718 Acinetobacter baumannii, Acinetobacter baumannii 1475764 Bacteria UP000028632, UP000020150 691047847, 589487101 EXH68127.1 WP_031995795.1 621 625 yes 1891124 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144309 Burkholderia sp. BT03 Bacteria UP000007299 495014206, 576729187 EUC17750.1 WP_007740217.1 642 643 yes 1891125 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1357269 Staphylococcus sp. EGD-HP3 Bacteria UP000016396 545089904, 537622986 ERF48448.1 WP_021459533.1 578 578 yes 1891126 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 816, 295405, 817, 1339304, 1339340, 1339339, 1339322, 1339318, 1339329, 1339331, 1339310, 1339320, 1339319, 1339332, 1339326, 1339328, 1339325, 1339324, 1339323, 1339330, 1339274, 1339303, 1339305, 1339306, 1339301, 1339294, 1339337, 1339295, 1339321, 1339317, 1339272, 1339273, 1339311, 1339298, 1339307, 1339299, 1339300, 1339292, 1339338, 1339327, 1339290, 1339271, 1339277, 1339278, 1339285, 1339316, 1339283, 1339289, 1339302, 1339313, 1339312, 1339309, 1339308, 1339293, 1073387, 665938, 469587, 457392, 272559 Bacteroides fragilis YCH46, Bacteroides fragilis, Bacteroides fragilis str. 3986 N3, Bacteroides fragilis str. 1007-1-F #6, Bacteroides fragilis str. 1007-1-F #5, Bacteroides fragilis str. S6R8, Bacteroides fragilis str. S6L5, Bacteroides fragilis str. S23L17, Bacteroides fragilis str. S38L3, Bacteroides fragilis str. 3783N1-6, Bacteroides fragilis str. S6R5, Bacteroides fragilis str. S6L8, Bacteroides fragilis str. S38L5, Bacteroides fragilis str. S36L5, Bacteroides fragilis str. S36L12, Bacteroides fragilis str. S24L34, Bacteroides fragilis str. S24L26, Bacteroides fragilis str. S24L15, Bacteroides fragilis str. S23L24, Bacteroides fragilis str. A7 (UDC12-2), Bacteroides fragilis str. 3986 T(B)13, Bacteroides fragilis str. 3986 N(B)22, Bacteroides fragilis str. 3719 T6, Bacteroides fragilis str. 3397 N3, Bacteroides fragilis str. 1007-1-F #9, Bacteroides fragilis str. 1007-1-F #3, Bacteroides fragilis str. 1007-1-F #10, Bacteroides fragilis str. S6R6, Bacteroides fragilis str. S6L3, Bacteroides fragilis str. J38-1, Bacteroides fragilis str. B1 (UDC16-1), Bacteroides fragilis str. 3783N1-8, Bacteroides fragilis str. 3725 D9(v), Bacteroides fragilis str. 3719 A10, Bacteroides fragilis str. 3397 T14, Bacteroides fragilis str. 3397 N2, Bacteroides fragilis str. 1007-1-F #7, Bacteroides fragilis str. 1007-1-F #4, Bacteroides fragilis str. S36L11, Bacteroides fragilis str. S13 L11, Bacteroides fragilis str. J-143-4, Bacteroides fragilis str. DS-71, Bacteroides fragilis str. DS-166, Bacteroides fragilis str. 3998 T(B) 4, Bacteroides fragilis str. 3998T(B)3, Bacteroides fragilis str. 3996 N(B) 6, Bacteroides fragilis str. 3986 N(B)19, Bacteroides fragilis str. 3986T(B)10, Bacteroides fragilis str. 3976T7, Bacteroides fragilis str. 3783N2-1, Bacteroides fragilis str. 3783N1-2, Bacteroides fragilis str. 3774 T13, Bacteroides fragilis str. 1007-1-F #8, Bacteroides fragilis HMW 615, Bacteroides sp. 2_1_56FAA, Bacteroides sp. 2_1_16, Bacteroides sp. 3_2_5, Bacteroides fragilis NCTC 9343 Bacteria UP000002197, UP000036847, UP000022647, UP000020935, UP000020856, UP000020474, UP000021466, UP000020274, UP000022345, UP000021175, UP000022450, UP000023441, UP000020053, UP000020620, UP000020419, UP000022653, UP000020683, UP000022819, UP000021519, UP000021728, UP000022978, UP000022280, UP000021084, UP000022058, UP000022068, UP000023428, UP000022433, UP000021499, UP000022005, UP000020285, UP000021470, UP000020682, UP000022575, UP000020262, UP000022784, UP000022581, UP000021025, UP000020314, UP000022082, UP000020732, UP000020740, UP000023349, UP000019914, UP000019974, UP000020773, UP000021400, UP000022567, UP000022118, UP000020723, UP000021095, UP000022040, UP000019993, UP000022683, UP000005831, UP000006425, UP000005743, UP000003869, UP000006731 492341708, 53713822, 663454631, 598896766, 598891026, 598880539, 598880050, 598874448, 598870926, 596277066, 596271733, 596266027, 596260579, 596255420, 596249176, 596242739, 596237433, 596232137, 596227056, 596221154, 596216027, 596210194, 596205460, 596200301, 596194923, 596173506, 596166637, 596161686, 596155678, 596150253, 596130613, 596122412, 596104255, 596099536, 596092975, 596088031, 596082666, 596071706, 596065247, 596058431, 596052273, 596044421, 596030698, 596017998, 596011230, 596004631, 595996086, 595971324, 595962702, 595956561, 595949520, 595942464, 595934047, 595890005, 404580694, 335945599, 263256775, 251946071, 81608438, 81314896, 60493474, 52216687 KER50119.1, EYE68648.1, EYE63141.1, EYE53413.1, EYE52952.1, EYE47669.1, EYE44333.1, EYB14577.1, EYB09817.1, EYB04653.1, EYA99990.1, EYA95623.1, EYA90350.1, EYA84748.1, EYA80079.1, EYA75468.1, EYA71049.1, EYA66066.1, EYA61969.1, EYA56582.1, EYA52332.1, EYA47796.1, EYA43186.1, EYA24421.1, EYA18536.1, EYA14117.1, EYA09075.1, EYA04131.1, EXZ88835.1, EXZ82777.1, EXZ67665.1, EXZ63485.1, EXZ57796.1, EXZ53259.1, EXZ48562.1, EXZ39011.1, EXZ33521.1, EXZ28235.1, EXZ24013.1, EXZ19004.1, EXZ09699.1, EXZ00197.1, EXY95185.1, EXY90255.1, EXY84240.1, EXY65280.1, EXY59967.1, EXY55705.1, EXY50897.1, EXY46131.1, EXY40539.1, EXY12851.1, EKA85403.1, EGN07409.1, EEZ28121.1, EES86478.1 WP_005815685.1, YP_099814.1 Q5LCA5, Q64T99 THIC_BACFN, THIC_BACFR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 828176, 732959 fig|469587.3.peg.1055, fig|272559.17.peg.2570, fig|295405.3.peg.2897, fig|1073387.4.peg.2727, fig|665938.3.peg.2756, fig|457392.3.peg.2697 564 564 yes 1891127 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316 Pseudomonas stutzeri Bacteria UP000037382 515815817 WP_017246570.1 627 627 yes 1891128 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204037, 579405 Dickeya dadantii Ech703 Bacteria UP000002734 506335647, 242133168 ACS87470.1 WP_015855366.1 fig|579405.3.peg.3936 631 650 yes 1891129 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 411472 Clostridium symbiosum ATCC 14940 Bacteria UP000016491 542975926 ERI73500.1 450 457 yes 1891130 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 104623 Serratia sp. ATCC 39006 Bacteria UP000017700 542097522, 555225927 ESN63380.1 WP_021014062.1 631 643 yes 1891131 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173950 Salmonella enterica, Salmonella enterica subsp. indica serovar 6,14,25:z10:1,(2),7 str. 1121 Bacteria UP000054489, UP000017304 554684806, 554037553 ESE83470.1 WP_023184706.1 626 631 yes 1891132 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262960 Ruminococcus sp. CAG:55 Environmental samples UP000018366 519805838 435 436 yes 1891133 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1042156 Clostridium sp. SY8519 Bacteria UP000008937 503743328, 338901938 WP_013977404.1 fig|1042156.4.peg.1530 435 436 yes 1891134 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 759350 Bifidobacterium longum, Bifidobacterium longum subsp. longum JDM301 Bacteria UP000028505, UP000006740 502906044, 666001104, 296183915 AIF90861.1, ADH00797.1 WP_013141020.1 fig|759350.3.peg.1332, fig|1266716.3.peg.698 635 917 yes 1891135 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 631, 349965 Yersinia intermedia, Yersinia intermedia ATCC 29909 Bacteria UP000041903, UP000005276 491334358, 238725710 EEQ17267.1 WP_005192317.1 fig|349965.3.peg.2540 652 672 yes 1891136 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423 Bacillus subtilis Bacteria UP000030083 518087645 WP_019257853.1 590 590 yes 1891137 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324 Stenotrophomonas maltophilia Bacteria UP000034806 518013606 WP_019183814.1 624 625 yes 1891138 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262757 Blautia sp. CAG:37 Environmental samples UP000018204 548243295, 524766873 WP_022461338.1 435 435 yes 1891139 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 606 612 yes 1891140 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 486, 869214 Neisseria lactamica, Neisseria lactamica Y92-1009 Bacteria UP000003015 489809039, 309379259 WP_003712900.1 fig|869214.3.peg.881 625 633 yes 1891141 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1335322, 1335420 Mycobacterium sp. MAC_080597_8934, Mycobacterium avium MAV_120809_2495 Bacteria UP000021997, UP000021111 576364327, 576353773 ETZ58596.1, ETZ48187.1 531 532 yes 1891142 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262785 Clostridium sp. CAG:253 Environmental samples UP000018071 547816179, 524444568 WP_022224991.1 434 435 yes 1891143 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262863 Coprococcus sp. CAG:782 Environmental samples UP000018002 547197371, 524074900 WP_021938666.1 435 436 yes 1891144 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 538379, 1329909 Sphingobium sp. P25, Sphingobium quisquiliarum P25 Bacteria UP000015525 544820937, 530267744 EQB10157.1 WP_021237153.1 611 615 yes 1891145 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287735, 1003200 Achromobacter sp. LMG 26845, Achromobacter xylosoxidans AXX-A Bacteria UP000004853 493436234, 338782633 EGP47005.1 WP_006391745.1 fig|1003200.3.peg.1645 636 637 yes 1891146 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144343 Phyllobacterium sp. YR531 Bacteria UP000007283 495398890, 398217503 EJN04020.1 WP_008123589.1 fig|1144343.3.peg.1695 600 605 yes 1891147 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1321822 Porphyromonas gingivalis F0566 Bacteria UP000016609 543982792 ERJ86392.1 599 609 yes 1891148 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 357 518855045 WP_020010935.1 600 607 yes 1891149 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1451189 Corynebacterium falsenii DSM 44353 Bacteria UP000019232 578014763 AHI03021.1 604 623 yes 1891150 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 621 631 yes 1891151 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1130304 crenarchaeote SCGC AAA261-N13 Archaea 516670819 WP_018033746.1 428 428 yes 1891152 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262953 Ruminococcus sp. CAG:254 Environmental samples UP000018181 547318133, 524215732 WP_022049570.1 440 441 yes 1891153 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204038, 590409 Dickeya dadantii, Dickeya dadantii Ech586 Bacteria UP000001446 502646646, 270342363 ACZ75128.1 WP_012882980.1 fig|590409.4.peg.234 629 653 yes 1891154 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1112209 Psychrobacter sp. PAMC 21119 Bacteria 497886606 WP_010200762.1 612 649 yes 1891155 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 774, 1293904, 1293905, 1293910, 1427331 Bartonella bacilliformis, Bartonella bacilliformis Ver075, Bartonella bacilliformis Peru38, Bartonella bacilliformis CUSCO5, Bartonella bacilliformis Peru-18 Bacteria UP000059456, UP000031736, UP000031739, UP000031741, UP000023119 737484191, 657181304, 657179591, 657176343, 601448056 KEG22569.1, KEG20874.1, KEG17666.1, EYS94993.1 WP_035463953.1 602 611 yes 1891156 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 897, 1121405 Desulfococcus multivorans, Desulfococcus multivorans DSM 2059 Bacteria UP000014977 527025523, 523468061 EPR39923.1 WP_020877253.1 432 432 yes 1891157 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316, 1212548 Pseudomonas stutzeri, Pseudomonas stutzeri NF13 Bacteria UP000037382, UP000011700 489395140, 452007302 EMD99559.1 WP_003301648.1 fig|1212548.4.peg.2748 626 626 yes 1891158 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116179, 1116103 Escherichia coli, Escherichia coli P0304816.3, Escherichia coli 180050 Bacteria UP000036210, UP000012215, UP000012198 487135095, 477466155, 476264840 ENH28663.1, EMW83404.1 WP_001627104.1 fig|1116179.3.peg.4297, fig|1116103.3.peg.4417 626 631 yes 1891159 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217712 Acinetobacter sp. NIPH 758 Bacteria UP000013049 490912064, 479944461 ENU90701.1 WP_004773980.1 fig|1217712.3.peg.3494 626 631 yes 1891160 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 71139 Eucalyptus grandis Plants UP000030711 702271096, 702271091, 702271082, 629120979, 629120978, 629120977, 629120976, 629120975 KCW85469.1, KCW85468.1, KCW85467.1, KCW85466.1, KCW85465.1 XP_010043455.1, XP_010043453.1, XP_010043452.1 556 647 yes 1891161 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1235788 Bacteroides massiliensis dnLKV3 Bacteria UP000014200 507751403 EOS10372.1 fig|1235788.3.peg.3441 565 565 yes 1891162 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 505 518 yes 1891163 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3760 Prunus persica Plants UP000006882 595836194, 462402849 EMJ08406.1 XP_007207207.1 536 538 yes 1891164 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317, 1194397 Pseudomonas syringae, Pseudomonas syringae pv. actinidiae ICMP 19101 Bacteria UP000028642, UP000015775 520967282, 519324717 EPN84371.1 WP_020363929.1 473 473 yes 1891165 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 936561 Fusobacterium sp. CM1 Bacteria UP000022778 696259615, 576686122 EUB39441.1 WP_032837239.1 433 433 yes 1891166 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262798 Clostridium sp. CAG:352 Environmental samples UP000018340 547858354, 524499451 WP_022265162.1 435 436 yes 1891167 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1121100 Bacteroides pyogenes DSM 20611 Bacteria UP000018842 567760411 498 498 no 1891168 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 540500 Psychrobacter lutiphocae Bacteria 518503812 WP_019674019.1 658 666 yes 1891169 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 77095, 752555 Prevotella bryantii, Prevotella bryantii B14 Bacteria UP000004524 493324209, 299776631 EFI73184.1 WP_006281474.1 564 564 yes 1891170 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1465 Brevibacillus laterosporus Bacteria 517499864 WP_018670441.1 591 592 yes 1891171 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 640132 Segniliparus rotundus DSM 44985 Bacteria UP000002247 296180814 ADG97720.1 fig|640132.3.peg.1265 543 552 yes 1891172 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1029823 Acinetobacter sp. P8-3-8 Bacteria 497798770 WP_010112954.1 635 639 yes 1891173 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1049804 Leptospira interrogans serovar Bataviae str. L1111 Bacteria UP000001148 410759494 EKR25706.1 505 515 yes 1891174 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76258 Vibrio rumoiensis Bacteria 515591717 WP_017024366.1 640 653 yes 1891175 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396 Bacillus cereus Bacteria UP000036076 516130507, 859522792, 821636592 KMP46451.1, KLA17496.1 WP_017561087.1 586 586 yes 1891176 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 135193 Paenibacillus daejeonensis Bacteria 522106335 WP_020617544.1 592 592 yes 1891177 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 85698, 762376 Achromobacter xylosoxidans, Achromobacter xylosoxidans A8 Bacteria UP000056101, UP000006876 503161988, 310763907 ADP19356.1 WP_013396649.1 fig|762376.5.peg.6075 636 637 yes 1891178 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 671143 NC10 bacterium 'Dutch sediment' Environmental samples UP000006898 506224357, 258592326 WP_015744132.1 fig|671143.5.peg.1383 440 442 yes 1891179 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33002, 694431 Desulfurella acetivorans, Desulfurella acetivorans A63 Bacteria UP000019023 644971642, 573478906 AHF97318.1 WP_025392396.1 427 427 yes 1891180 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1160895 Acidianus sp. ALE_1 Archaea 851188379, 612165332 EZQ01997.1 WP_048100388.1 A0A031LIN3 A0A031LIN3_9CREN 437 437 yes 1891181 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262932 Prevotella sp. CAG:604 Environmental samples UP000018295 547563274, 524294104 WP_022111616.1 240 240 no 1891182 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316997, 987059 Rubrivivax benzoatilyticus, Rubrivivax benzoatilyticus JA2 Bacteria UP000005494 497544727, 332112567 EGJ12360.1 WP_009858925.1 621 636 yes 1891183 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262769 Clostridium sp. CAG:1013 Environmental samples UP000018382 512135809, 511346716 WP_016404777.1 171 171 no 1891184 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 859058, 1238182 Caenispirillum sp. AK4, Caenispirillum salinarum AK4 Bacteria UP000009881 497228331, 425877966 EKV26689.1 WP_009542593.1 fig|1238182.3.peg.4152 606 608 yes 1891185 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1055328 Neisseria meningitidis NM233 Bacteria UP000005036 372200072 EHP14205.1 fig|1077282.3.peg.2315, fig|1145183.3.peg.2486, fig|1079756.3.peg.2267, fig|1079752.3.peg.1985, fig|1145184.3.peg.2647, fig|1079755.3.peg.1819, fig|1055328.3.peg.2099, fig|1145182.3.peg.2474, fig|1145187.3.peg.2448 625 658 yes 1891186 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61598 Lamprocystis purpurea Bacteria 521993284 WP_020504555.1 628 630 yes 1891187 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444062, 1444103, 1444157, 1116171 Escherichia coli, Escherichia coli 6-319-05_S1_C1, Escherichia coli 7-233-03_S1_C3, Escherichia coli 5-366-08_S3_C2, Escherichia coli P0304777.10 Bacteria UP000036210, UP000028101, UP000027702, UP000027758, UP000012432 489697840, 660204850, 660204628, 660082537, 477165061 KEM96842.1, KEM96625.1, KEL77855.1, ENE42166.1 WP_003601990.1 fig|1116171.3.peg.4685 626 631 yes 1891188 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1288787, 1238215 Vibrio parahaemolyticus, Vibrio parahaemolyticus 3355, Vibrio parahaemolyticus NIHCB0757 Bacteria UP000028114, UP000032112, UP000017027 546182646, 758019853, 655664891, 532606921 KIT31416.1, KED60157.1, EQM40723.1 WP_021823349.1 640 646 yes 1891189 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444061 Escherichia coli, Escherichia coli 6-175-07_S1_C1 Bacteria UP000036210, UP000028048 585350375, 660051155 KEL47346.1 WP_024231989.1 626 631 yes 1891190 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 981085 Morus notabilis Plants UP000030645 703130660, 587913681 EXC01484.1 XP_010104678.1 541 647 yes 1891191 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1125977 Pseudomonas sp. PAMC 25886 Bacteria 497855174 WP_010169330.1 628 629 yes 1891192 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144313 Flavobacterium sp. CF136 Bacteria UP000007287 495084055, 398071378 EJL62637.1 WP_007808879.1 fig|1144313.4.peg.2798 607 607 yes 1891193 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2173 Methanobrevibacter smithii Archaea 518096330 WP_019266538.1 432 432 yes 1891194 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354276, 61645, 550, 1329832 Enterobacter asburiae, Enterobacter cloacae, Enterobacter sp. MGH 34 Bacteria UP000036088, UP000036177, UP000017617 556474863, 771232047, 771026963, 736276922, 555143503 KJN69665.1, KJM14962.1, KHQ31871.1, ESM86242.1 WP_023326468.1 626 631 yes 1891195 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 348388, 1217705, 1217711 Acinetobacter sp. AG1, Acinetobacter sp. ANC 3862, Acinetobacter sp. NIPH 236 Bacteria UP000033844, UP000013248, UP000013190 490797253, 819913262, 480162093, 479877210 KKW79389.1, ENW98894.1, ENU28390.1 WP_004659392.1 fig|1217711.3.peg.471, fig|1217705.3.peg.2894 626 631 yes 1891196 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423, 1052588 Bacillus subtilis, Bacillus subtilis subsp. subtilis RO-NN-1 Bacteria UP000030083, UP000002652 504289121, 349593789 AEP89976.1 WP_014476223.1 fig|1052588.4.peg.913 590 590 yes 1891197 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 839, 264731 Prevotella ruminicola, Prevotella ruminicola 23 Bacteria UP000000927 502829218, 294472818 ADE82207.1 WP_013064194.1 fig|264731.4.peg.387 527 528 yes 1891198 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1681, 702459 Bifidobacterium bifidum, Bifidobacterium bifidum PRL2010 Bacteria UP000035497, UP000002312 503154965, 311063899, 827583692, 310866218 KLN86804.1, ADP35587.1 WP_013389626.1, YP_003970624.1 fig|702459.3.peg.498 637 918 yes 1891199 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298599 Vibrio owensii JCM 18904 Bacteria UP000026909 635167336 638 644 yes 1891200 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1121832 Fodinicurvata sediminis Bacteria 550979456 WP_022727565.1 598 601 yes 1891201 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 300, 1001585 Pseudomonas mendocina, Pseudomonas mendocina NK-01 Bacteria UP000028008, UP000008306 503479167, 328915882 AEB56713.1 WP_013713828.1 fig|1001585.3.peg.692 627 627 yes 1891202 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1385, 1246477, 1144311 Brevibacillus agri BAB-2500, Brevibacillus sp. CF112 Bacteria UP000010742, UP000007279 492406145, 432182736, 398054907 ELK40299.1, EJL47005.1 WP_005834379.1 fig|1246477.3.peg.4235, fig|1144311.3.peg.705 583 583 yes 1891203 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1035, 883080 Afipia felis, Afipia felis ATCC 53690 Bacteria UP000035762, UP000001342 488804258, 410881225 EKS29065.1 WP_002716664.1 fig|883080.3.peg.1648 628 638 yes 1891204 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 861208 Agrobacterium sp. H13-3 Bacteria UP000007455 325061793 ADY65484.1 fig|861208.3.peg.2537 600 608 yes 1891205 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1124967 Salmonella enterica, Salmonella enterica subsp. enterica serovar Soerenga str. 695 Bacteria UP000054489, UP000017504 554962019, 554131492 ESF72004.1 WP_023206546.1 626 631 yes 1891206 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 502025 Haliangium ochraceum DSM 14365 Bacteria UP000001880 262081739 ACY17708.1 fig|502025.10.peg.5288 536 567 yes 1891207 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 861365 Klebsiella pneumoniae subsp. rhinoscleromatis SB3432 Bacteria UP000013942 499528186 626 635 yes 1891208 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1232189 Clostridium botulinum CFSAN001627 Bacteria UP000011944 409741161 EKN41110.1 fig|1232189.3.peg.2410 437 437 yes 1891209 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28223, 651182 Desulfobacula toluolica, Desulfobacula toluolica Tol2 Bacteria UP000007347 504768482, 405104729 WP_014955584.1 fig|651182.5.peg.68 429 429 yes 1891210 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 1400152 Enterobacter cloacae, Enterobacter cloacae UCI 39 Bacteria UP000036177, UP000022610 695749496, 578198853 EUL59108.1 WP_032675760.1 626 631 yes 1891211 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 151895, 762903 Pedobacter saltans, Pedobacter saltans DSM 12145 Bacteria UP000000310 503397789, 324972967 ADY51951.1 WP_013632450.1 fig|762903.3.peg.2811 626 626 yes 1891212 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 372 373 yes 1891213 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 31958, 1156913 Amycolatopsis orientalis, Amycolatopsis orientalis HCCB10007 Bacteria UP000013968 511270438, 505820013 AGM09936.1 WP_016337620.1 fig|1156913.3.peg.7502 544 547 yes 1891214 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 489722, 1297569 Mesorhizobium metallidurans, Mesorhizobium metallidurans STM 2683 Bacteria UP000012062 496150247, 472143867 WP_008874754.1 fig|1297569.3.peg.2658 597 612 yes 1891215 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2371, 788929, 183190 Xylella fastidiosa, Xylella fastidiosa subsp. fastidiosa GB514, Xylella fastidiosa Temecula1 Bacteria UP000028529, UP000008704, UP000002516 499410369, 307579958, 32130180 ADN63927.1 WP_011097836.1 Q87CY6 THIC_XYLFT Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 2155377, 5575534 fig|405441.5.peg.1198, fig|183190.5.peg.1174, fig|945689.3.peg.1607 595 603 yes 1891216 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358, 1281779 Agrobacterium tumefaciens, Agrobacterium sp. Cherry 2E-2-2 Bacteria UP000064781, UP000012074 489616868, 474938335 EMS98011.1 WP_003521308.1 fig|1281779.3.peg.1931 600 607 yes 1891217 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 514843461 WP_016588655.1 446 457 yes 1891218 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84156, 572546 Archaeoglobus profundus, Archaeoglobus profundus DSM 5631 Archaea UP000001901 502705892, 284012833 ADB58786.1 WP_012941121.1 D2RF92 D2RF92_ARCPA 417 435 yes 1891219 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 645578 Methylovulum miyakonense Bacteria 518703884 WP_019865003.1 624 624 yes 1891220 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1938, 591159 Streptomyces viridochromogenes, Streptomyces viridochromogenes DSM 40736 Bacteria UP000037613, UP000004184 490089507, 302470259 EFL33352.1 WP_003991461.1 598 600 yes 1891221 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1112213 Sphingomonas sp. PAMC 26621 Bacteria 497900260 WP_010214416.1 637 639 yes 1891222 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 653930 Pseudomonas sp. BZ93 Bacteria UP000024226 612182660 EZQ18612.1 625 627 yes 1891223 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 817, 1339335 Bacteroides fragilis, Bacteroides fragilis str. 3-F-2 #6 Bacteria UP000036847, UP000019827 695499178, 596117010 EXZ78207.1 WP_032581572.1 203 203 no 1891224 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217693 Acinetobacter sp. NIPH 2171 Bacteria UP000013101 491375604, 480174127 ENX10654.1 WP_005233496.1 fig|1217693.3.peg.819 626 631 yes 1891225 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 329, 1366050 Ralstonia pickettii, Ralstonia pickettii DTP0602 Bacteria UP000029114, UP000016821 549494891, 546336329 AGW88578.1 WP_022533293.1 624 626 yes 1891226 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1055526 Candidatus Burkholderia kirkii UZHbot1 Bacteria UP000003511 350526879 fig|1055526.3.peg.3625 642 643 yes 1891227 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2426 Teredinibacter turnerae Bacteria 518433770 WP_019603977.1 638 639 yes 1891228 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 199, 929793 Campylobacter concisus, Campylobacter concisus UNSWCD Bacteria UP000066049, UP000003098 489030784, 384577599 EIF06880.1 WP_002941173.1 fig|929793.3.peg.1058 431 431 yes 1891229 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 77133 uncultured bacterium Environmental samples UP000041370 406981033 EKE02558.1 420 420 yes 1891230 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4533 Oryza brachyantha Plants UP000006038 573925730 XP_006650406.1 550 652 yes 1891231 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 999151, 1286106 Methylophaga lonarensis, Methylophaga lonarensis MPL Bacteria UP000012019 497410921, 471184272 EMR14377.1 WP_009725119.1 fig|1286106.3.peg.46 600 602 yes 1891232 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 45462, 1300222 Brevibacillus borstelensis, Brevibacillus borstelensis AK1 Bacteria UP000012081 489481410, 475661584 EMT54602.1 WP_003386392.1 fig|1300222.3.peg.704 595 598 yes 1891233 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 231455, 1217721 Dyella japonica, Dyella japonica A8 Bacteria UP000027987 518294843, 664783010 AIF45777.1 WP_019465051.1 622 625 yes 1891234 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1225179 Bartonella quintana RM-11 Bacteria UP000009208 403232389 AFR26132.1 fig|1225179.3.peg.531 594 595 yes 1891235 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1003110, 263358 Verrucosispora maris, Verrucosispora sp. AB-18-032 Bacteria UP000053246, UP000008308 503501254, 328813099 AEB47271.1 WP_013735915.1 fig|263358.5.peg.5350 530 530 yes 1891236 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287 Pseudomonas aeruginosa Bacteria UP000065817 518226579 WP_019396787.1 576 577 yes 1891237 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2285, 1435377 Sulfolobus acidocaldarius, Sulfolobus acidocaldarius SUSAZ Archaea UP000065473, UP000060777 568208531, 566046770 AHC50655.1 WP_024082895.1 V9S3H2 V9S3H2_9CREN 427 428 yes 1891238 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262687 Acidaminococcus sp. CAG:542 Environmental samples UP000018195 548295560, 524796952 WP_022487020.1 435 435 yes 1891239 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 171695, 667014 Thermodesulfatator indicus, Thermodesulfatator indicus DSM 15286 Bacteria UP000006793 503673641, 335359294 AEH44975.1 WP_013907717.1 fig|667014.3.peg.1134 433 434 yes 1891240 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1095667 Neisseria meningitidis, Neisseria meningitidis 77221 Bacteria UP000050419, UP000010746 488180440, 432270397 ELL25535.1 WP_002251648.1 fig|1095667.3.peg.2698 625 633 yes 1891241 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1175452 Peptoniphilus rhinitidis Bacteria 497930433 WP_010244589.1 432 433 yes 1891242 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 99598 Calothrix sp. PCC 7507 Bacteria UP000010390 504944386, 427352973 AFY35697.1 WP_015131488.1 fig|99598.3.peg.6003 455 457 yes 1891243 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1210046 Janibacter hoylei PVAS-1 Bacteria UP000004474 404557389 EKA62837.1 fig|1210046.3.peg.45 580 583 yes 1891244 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 199, 1242965 Campylobacter concisus, Campylobacter concisus UNSW2 Bacteria UP000066049, UP000016625 544659344, 543212521 ERJ31534.1 WP_021092956.1 431 431 yes 1891245 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 523791 Kangiella koreensis DSM 16069 Bacteria UP000001231 256794891 ACV25547.1 fig|523791.5.peg.117 614 615 yes 1891246 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1032505 Fusobacterium sp. OBRC1 Bacteria UP000023259 696258133, 576676671 EUB30246.1 WP_032835817.1 433 433 yes 1891247 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 665949 Tannerella sp. 6_1_58FAA_CT1 Bacteria UP000004488 496676756, 363642499 EHL81851.1 WP_009319246.1 fig|665949.3.peg.2949 565 565 yes 1891248 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1390, 1390372 Bacillus amyloliquefaciens, Bacillus amyloliquefaciens EGD-AQ14 Bacteria UP000027101, UP000016484 545133533, 542006096 ERH52009.1 WP_021494875.1 590 590 yes 1891249 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 521674 Planctomyces limnophilus DSM 3776 Bacteria UP000002220 296014333 ADG67572.1 fig|521674.4.peg.3690 516 617 yes 1891250 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 883156 Neisseria sp. ACS-216-V-Col6b Bacteria UP000009891 425715496 EKU78484.1 fig|883156.3.peg.1080 451 451 yes 1891251 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 596152 Desulfovibrio sp. U5L Bacteria UP000003968 496399942, 385733899 EIG54097.1 WP_009108932.1 418 437 no 1891252 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 941188 Salmonella enterica, Salmonella enterica subsp. enterica serovar Pomona str. ATCC 10729 Bacteria UP000054489, UP000004971 446030562, 366078071 EHN42077.1 WP_000108417.1 fig|941188.3.peg.4071 626 631 yes 1891253 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 28901, 913069 Salmonella enterica, Salmonella enterica subsp. enterica serovar Baildon str. R6-199 Bacteria UP000054489, UP000003651 446030560, 357953129 EHJ79788.1 WP_000108415.1 182 193 no 1891254 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 930777, 702983 Salmonella enterica, Salmonella enterica subsp. enterica serovar Paratyphi B str. ATCC 8759, Salmonella enterica subsp. enterica serovar Paratyphi B str. SARA56 Bacteria UP000054489, UP000017436, UP000017455 446030567, 554148244, 554037213 ESF88220.1, ESE83135.1 WP_000108422.1 626 631 yes 1891255 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 28901 Salmonella enterica Bacteria UP000054489 446030564 WP_000108419.1 515 518 no 1891256 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 859, 556263 Fusobacterium necrophorum, Fusobacterium sp. D12 Bacteria UP000004314 496293826, 340573874 EFS22443.2 WP_009005864.1 fig|556263.3.peg.50 433 433 yes 1891257 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553239 Vibrio breoganii Bacteria 515599451 WP_017032051.1 640 643 yes 1891258 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1172190 Sulfurimonas sp. AST-10 Bacteria UP000015520 544875387, 530446189 EQB34439.1 WP_021288420.1 465 466 yes 1891259 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 454171, 1303518 candidate division OP10 bacterium T49, Chthonomonas calidirosea T49 Bacteria UP000050785, UP000014227 512724987, 510023416 WP_016482997.1 444 449 yes 1891260 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 115808 Bradyrhizobium sp. ORS285 Bacteria UP000005989 493664133, 365269434 WP_006615392.1 fig|115808.3.peg.6544 622 633 yes 1891261 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82996 Serratia plymuthica Bacteria UP000025240 619730035 AHY05275.1 633 647 yes 1891262 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1764 Mycobacterium avium Bacteria 515075923 WP_016705731.1 530 532 yes 1891263 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1284629 Crocosphaera watsonii WH 0402 Bacteria UP000018130 543535992 205 205 no 1891264 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1284629 Crocosphaera watsonii WH 0402 Bacteria UP000018130 543535990 171 171 no 1891265 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1201294 Methanoculleus bourgensis MS2 Archaea UP000009007 396940206 I7KE49 I7KE49_METBM 405 455 no 1891266 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217695 Acinetobacter sp. NIPH 1859 Bacteria UP000013009 491420588, 480195914 ENX31921.1 WP_005278386.1 fig|1217695.3.peg.3698 626 631 yes 1891267 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553384, 1195246 Alishewanella sp. BL06, Alishewanella agri BL06 Bacteria UP000035062 496271295, 392607699 EIW90573.1 WP_008983333.1 fig|1195246.3.peg.366 598 623 yes 1891268 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 192259 Genlisea aurea Plants UP000015453 527192969 EPS63180.1 554 623 yes 1891269 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 80880, 887062 Hylemonella gracilis, Hylemonella gracilis ATCC 19624 Bacteria UP000016368 493341442, 332040066 EGI76451.1 WP_006298318.1 628 633 yes 1891270 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 457415 Synergistes sp. 3_1_syn1 Bacteria UP000003380 495988895, 363612080 EHL63638.1 WP_008713474.1 fig|457415.3.peg.3001 434 435 yes 1891271 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 653685, 1452, 1495315, 1529886, 334727, 720555 Bacillus atrophaeus, Bacillus subtilis subsp. niger, Bacillus atrophaeus subsp. globigii, Bacillus sp. C89, Bacillus atrophaeus 1942 Bacteria UP000031779, UP000029118, UP000028950, UP000003007, UP000006867 490565074, 751415414, 674581485, 673982435, 388473243, 310867880 AJF84201.1, KFK81661.1, AIK49131.1, EIM09989.1, ADP31355.1 WP_004430100.1 fig|334727.3.peg.2932, fig|743710.3.peg.514, fig|720558.3.peg.2542, fig|720557.3.peg.2251, fig|743711.3.peg.3393, fig|723889.3.peg.1020, fig|720555.4.peg.401, fig|903520.3.peg.2021, fig|723888.3.peg.147, fig|723892.3.peg.3710, fig|882455.3.peg.7, fig|882453.3.peg.2416, fig|720556.3.peg.320, fig|876283.3.peg.1076 590 590 yes 1891272 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35823, 459495 Arthrospira platensis C1 Bacteria UP000006749 493672228, 406714349 EKD09516.1 WP_006622561.1 459 461 yes 1891273 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294 Pseudomonas fluorescens Bacteria UP000060991 515705889 WP_017138489.1 628 634 yes 1891274 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 237727 Erythrobacter sp. NAP1 Bacteria UP000002995 494288437, 85687952 EAQ27956.1 WP_007165162.1 fig|237727.3.peg.2065 626 630 yes 1891275 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 518 Bordetella bronchiseptica Bacteria UP000064190 754778972, 613405676 WP_042142881.1 636 637 yes 1891276 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169350 Citrobacter sp. KTE32 Bacteria UP000014007 507087206, 500560763 EOQ24351.1 WP_016157946.1 fig|1169350.3.peg.4599 626 632 yes 1891277 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 489138 Halarchaeum acidiphilum Archaea 519066232 WP_020222107.1 437 464 yes 1891278 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47229, 883126 Massilia timonae, Massilia timonae CCUG 45783 Bacteria UP000009874 491913578, 425718350 EKU81297.1 WP_005667961.1 fig|883126.3.peg.3161 636 641 yes 1891279 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 658089 Lachnospiraceae bacterium 5_1_63FAA Bacteria UP000005278 496559422, 316893643 EFV15845.1 WP_009265497.1 433 433 yes 1891280 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265601 Streptomyces sp. PAMC26508 Bacteria UP000012995 505390834, 478747506 AGJ56086.1 WP_015577936.1 fig|1265601.4.peg.3450 586 612 yes 1891281 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1101192 Methylobacterium sp. 77 Bacteria 518748266 WP_019906555.1 626 635 yes 1891282 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1190581, 1190578, 1190573, 1190569, 1145167, 1145157, 1145143, 1145144, 1145141, 1145142, 1145140, 1145138, 1145139, 1145137, 1145136, 1145135, 1145131, 1145130, 1145129, 1145128, 1145125, 1145126, 1145123, 1145124, 1145122, 1145121, 1145120, 1145119, 1095666, 1095668, 1095669, 1095670, 1095671, 1095672, 1095673, 1095676, 1095677, 1095679, 1095680, 1095681, 1095682, 1095695, 1095696, 1095698, 1095700, 1069621, 1069616, 1069615, 1069614, 1069613, 1069611, 1069612, 1069609, 935599, 935598, 935594, 935592, 630588, 942513, 295996 Neisseria meningitidis, Neisseria meningitidis NM2866, Neisseria meningitidis NM518, Neisseria meningitidis NM045, Neisseria meningitidis 96037, Neisseria meningitidis 2001001, Neisseria meningitidis 73696, Neisseria meningitidis NM606, Neisseria meningitidis NM607, Neisseria meningitidis 2002007, Neisseria meningitidis NM604, Neisseria meningitidis 2000063, Neisseria meningitidis 2004085, Neisseria meningitidis 2003022, Neisseria meningitidis 98005, Neisseria meningitidis 97008, Neisseria meningitidis 96024, Neisseria meningitidis 70082, Neisseria meningitidis 61106, Neisseria meningitidis 63023, Neisseria meningitidis 97018, Neisseria meningitidis 75643, Neisseria meningitidis 75689, Neisseria meningitidis 96060, Neisseria meningitidis 94018, Neisseria meningitidis 2000080, Neisseria meningitidis 70021, Neisseria meningitidis 69176, Neisseria meningitidis 69155, Neisseria meningitidis 70030, Neisseria meningitidis 2001212, Neisseria meningitidis 2007056, Neisseria meningitidis NM3642, Neisseria meningitidis NM3652, Neisseria meningitidis 69096, Neisseria meningitidis 97020, Neisseria meningitidis 96023, Neisseria meningitidis 2004090, Neisseria meningitidis 4119, Neisseria meningitidis 12888, Neisseria meningitidis 9757, Neisseria meningitidis 9506, Neisseria meningitidis 70012, Neisseria meningitidis 88050, Neisseria meningitidis 68094, Neisseria meningitidis 87255, Neisseria meningitidis NM3081, Neisseria meningitidis 98008, Neisseria meningitidis NM576, Neisseria meningitidis 69166, Neisseria meningitidis NM2781, Neisseria meningitidis NM140, Neisseria meningitidis NM183, Neisseria meningitidis 93004, Neisseria meningitidis G2136, Neisseria meningitidis 961-5945, Neisseria meningitidis M13399, Neisseria meningitidis OX99.30304, Neisseria meningitidis alpha710, Neisseria meningitidis WUE 2594, Neisseria meningitidis alpha275 Bacteria UP000050419, UP000015798, UP000015862, UP000015891, UP000015804, UP000013356, UP000013314, UP000013316, UP000013335, UP000013323, UP000013358, UP000013368, UP000013326, UP000013663, UP000013371, UP000013381, UP000013387, UP000013334, UP000013333, UP000013328, UP000017220, UP000013367, UP000013374, UP000013324, UP000013361, UP000013310, UP000013355, UP000013369, UP000013327, UP000010749, UP000010759, UP000010754, UP000010728, UP000010737, UP000010756, UP000010726, UP000010747, UP000010766, UP000010752, UP000010738, UP000010755, UP000010731, UP000010734, UP000010743, UP000010730, UP000010732, UP000005241, UP000004392, UP000005057, UP000005072, UP000005027, UP000004809, UP000003115, UP000003130, UP000007479, UP000004866, UP000006022, UP000005562, UP000006929, UP000008638 488148738, 837359781, 530921294, 530915184, 530904745, 530900692, 485369541, 485347288, 485328519, 485327081, 485320536, 485320189, 485318819, 485313654, 485313564, 485311582, 485306902, 485306519, 485299222, 485293120, 485292683, 485292469, 485285983, 485285788, 485281204, 485279584, 485279339, 485272497, 485272463, 485272345, 432270849, 432269099, 432264670, 432263772, 432263501, 432257930, 432257489, 432251085, 432250778, 432244744, 432244489, 432238614, 432238490, 432212877, 432207330, 432206335, 432200950, 402340370, 402328706, 402327422, 402327066, 402323157, 402320915, 402320728, 402314824, 325199132, 325141400, 325133367, 325129359, 308390138, 810109166, 809897818, 809889564, 809885500, 809841072, 809834784, 809754810, 801291423, 801223786, 801162239, 801135424, 800245986, 319409648, 254673739 AKM89813.1, EQD18705.1, EQD12962.1, EQD03156.1, EQC99364.1, EOC29562.1, EOC09064.1, EOB91545.1, EOB90208.1, EOB84096.1, EOB83782.1, EOB82512.1, EOB77670.1, EOB77589.1, EOB75751.1, EOB71354.1, EOB71002.1, EOB64214.1, EOB58496.1, EOB58101.1, EOB57921.1, EOB51834.1, EOB51659.1, EOB47338.1, EOB45836.1, EOB45609.1, EOB39239.1, EOB39206.1, EOB39097.1, ELL25982.1, ELL24262.1, ELL19869.1, ELL18983.1, ELL18718.1, ELL13222.1, ELL12789.1, ELL06457.1, ELL06158.1, ELL00227.1, ELK99977.1, ELK94179.1, ELK94056.1, ELK68808.1, ELK63320.1, ELK62344.1, ELK57037.1, EJU75571.1, EJU64072.1, EJU62810.1, EJU62462.1, EJU58603.1, EJU56395.1, EJU56209.1, EJU50392.1, ADY94588.1, EGC63879.1, EGC56032.1, EGC52194.1, ADO32458.1 WP_002219946.1 fig|1095676.3.peg.2609, fig|942513.4.peg.166, fig|1095670.3.peg.2713, fig|1069614.3.peg.2687, fig|1095700.3.peg.2625, fig|1145136.3.peg.2630, fig|1145143.3.peg.900, fig|1069611.3.peg.2651, fig|1095669.3.peg.2616, fig|1145126.3.peg.2620, fig|1095677.3.peg.2752, fig|1095671.3.peg.2617, fig|1095695.3.peg.2719, fig|1145130.3.peg.2710, fig|1145142.3.peg.2677, fig|1079754.3.peg.1593, fig|1069612.3.peg.2616, fig|1145141.3.peg.2562, fig|1069609.3.peg.2868, fig|1145157.3.peg.2660, fig|1069621.3.peg.2896, fig|1095682.3.peg.2678, fig|1095696.3.peg.2631, fig|1172206.3.peg.2424, fig|935598.3.peg.2688, fig|1145131.3.peg.2655, fig|935592.3.peg.2483, fig|1095673.3.peg.2630, fig|1145122.3.peg.2540, fig|1095668.3.peg.2657, fig|1145135.3.peg.2543, fig|935599.3.peg.2611, fig|1069616.3.peg.2627, fig|1069615.3.peg.2593, fig|1095698.3.peg.2617, fig|1095679.3.peg.2625, fig|1145144.3.peg.2576, fig|1145119.3.peg.2717, fig|1095680.3.peg.2791, fig|1145140.3.peg.2625, fig|1095666.3.peg.2723, fig|1145129.3.peg.2645, fig|1095681.3.peg.2728, fig|1145139.3.peg.2564, fig|1145138.3.peg.2582, fig|1095672.3.peg.2718, fig|1145167.3.peg.2573, fig|1145123.3.peg.1738, fig|1145125.3.peg.2548, fig|1145124.3.peg.2538, fig|1069613.3.peg.2609, fig|1145121.3.peg.2648, fig|935594.3.peg.2712, fig|1145137.3.peg.2583, fig|1145120.3.peg.2661, fig|630588.3.peg.2731 625 633 yes 1891283 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1129897 Nitrolancetus hollandicus Lb Bacteria UP000004221 390174683 fig|1129897.3.peg.168 588 588 yes 1891284 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 425 425 yes 1891285 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 283734, 937773 Staphylococcus pseudintermedius, Staphylococcus pseudintermedius HKU10-03 Bacteria UP000069715, UP000007469 505962824, 317163228 ADV06771.1 WP_015729704.1 fig|937773.3.peg.2243 578 578 yes 1891286 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 639 645 yes 1891287 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 129337, 1422, 1233873 Geobacillus stearothermophilus, Geobacillus sp. GHH01 Bacteria UP000036745, UP000011251 505186793, 679860019, 674749890, 445205492 KFX31809.1, KFL16417.1, AGE20957.1 WP_015373895.1 fig|1233873.3.peg.385 562 562 yes 1891288 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1284392 Pseudomonas extremorientalis FH1 Bacteria UP000018863 727814388, 567648580 ETK23782.1 WP_033897850.1 628 629 yes 1891289 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 516074, 1141662 Providencia burhodogranariea, Providencia burhodogranariea DSM 19968 Bacteria UP000009336 496188327, 414096443 EKT58101.1 WP_008912834.1 fig|1141662.3.peg.2887 623 649 yes 1891290 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1126627 Bradyrhizobium sp. DOA9 Bacteria UP000066441 640606135, 608612846 WP_025034483.1 fig|663886.3.peg.1538, fig|1773.31.peg.2930, fig|336982.3.peg.1435, fig|478434.4.peg.2925, fig|663887.3.peg.1535, fig|555461.3.peg.1665, fig|537209.3.peg.1649, fig|707235.4.peg.1488, fig|478435.3.peg.1465, fig|478433.3.peg.1533 623 632 yes 1891291 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573 Klebsiella pneumoniae Bacteria UP000036212 516512679 WP_017901117.1 626 631 yes 1891292 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 797057 Amycolatopsis orientalis subsp. vinearia Bacteria 397911986 AFO69315.1 542 544 yes 1891293 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 92245, 717772 Thioalkalimicrobium aerophilum, Thioalkalimicrobium aerophilum AL2 Bacteria UP000005380 493505682, 570730851 AHF02071.1 WP_006460122.1 619 625 yes 1891294 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 745016, 745022 Salmonella enterica subsp. enterica serovar Montevideo str. 316111868, Salmonella enterica subsp. enterica serovar Montevideo str. 531954 Bacteria UP000028650, UP000004360 444832430, 322642608 ELX59644.1, EFY39203.1 fig|745022.3.peg.951 483 485 yes 1891295 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262870 Dialister sp. CAG:486 Environmental samples UP000017985 547522682, 524289241 WP_022106400.1 433 434 yes 1891296 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553220 Campylobacter gracilis RM3268 Bacteria UP000005709 257442593 EEV17732.1 fig|553220.3.peg.1401 492 493 yes 1891297 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 1445865 Serratia marcescens, Serratia marcescens BIDMC 81 Bacteria UP000055021, UP000023834 727190928, 612262905 EZQ56498.1 WP_033652709.1 632 647 yes 1891298 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1048680 Rhizobium sp. 42MFCr.1 Bacteria 517685652 WP_018855860.1 601 608 yes 1891299 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59732, 1144316 Chryseobacterium sp. CF314 Bacteria UP000007509 495119343, 398080330 EJL71147.1 WP_007844158.1 fig|1144316.3.peg.2559 603 603 yes 1891300 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280683 Butyrivibrio sp. NC2007 Bacteria 551024693 WP_022768823.1 438 441 yes 1891301 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 533240 Cylindrospermopsis raciborskii CS-505 Bacteria UP000052045 281195775 EFA70703.1 469 473 yes 1891302 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 1095657 Vibrio cholerae, Vibrio cholerae O1 str. NHCC-008D Bacteria UP000028983, UP000012154 488091248, 469752501 EMQ64765.1 WP_002162645.1 fig|1095657.3.peg.2909 639 645 yes 1891303 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61435, 1193807 Dehalococcoides ethenogenes, Dehalococcoides mccartyi DCMB5 Bacteria UP000054393, UP000011720 505219944, 452110629 AGG06361.1 WP_015407046.1 fig|1193807.4.peg.727 430 431 yes 1891304 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 763034 Bacteroides fluxus YIT 12057 Bacteria UP000003416 328529813 EGF56705.1 567 568 yes 1891305 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35818, 537972 Helicobacter pullorum, Helicobacter pullorum MIT 98-5489 Bacteria UP000037800, UP000003953 491162337, 239522883 EEQ62749.1 WP_005020719.1 fig|537972.5.peg.407 442 443 yes 1891306 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 549169, 1388764 Lutiella nitroferrum, Pseudogulbenkiania ferrooxidans EGD-HP2 Bacteria UP000016426 545111974, 537050337 ERE20760.1 WP_021474949.1 631 632 yes 1891307 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 293, 751586 Brevundimonas diminuta, Brevundimonas diminuta ATCC 11568 Bacteria UP000002955 489255926, 328846977 EGF96539.1 WP_003163872.1 619 635 yes 1891308 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28251, 1401326, 1401325, 867902 Ornithobacterium rhinotracheale, Ornithobacterium rhinotracheale H06-030791, Ornithobacterium rhinotracheale ORT-UMN 88, Ornithobacterium rhinotracheale DSM 15997 Bacteria UP000029645, UP000029420, UP000006051 504604834, 686579247, 686513620, 390522704 KGB65755.1, AIQ00166.1, AFL98435.1 WP_014791936.1 fig|867902.3.peg.2255 618 618 yes 1891309 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 253239, 663278 Ethanoligenens harbinense, Ethanoligenens harbinense YUAN-3 Bacteria UP000001551 503249543, 315469219 ADU25823.1 WP_013484204.1 fig|663278.4.peg.274 432 432 yes 1891310 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 332273 uncultured bacterium MedeBAC35C06 Environmental samples 67906501 AAY82608.1 481 481 yes 1891311 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 817, 1339279 Bacteroides fragilis, Bacteroides fragilis str. 20793-3 Bacteria UP000036847, UP000021122 695496034, 596188271 EYA37310.1 WP_032580493.1 343 364 no 1891312 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1193059 Leptospira santarosai str. CBC1416 Bacteria UP000012149 464390150 EMO60144.1 520 520 yes 1891313 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 252583, 1219080 Vibrio ezurae, Vibrio ezurae NBRC 102218 Bacteria UP000016562 545477993, 543449658 WP_021714134.1 640 641 yes 1891314 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262923 Prevotella sp. CAG:255 Environmental samples UP000017913 546380597, 523982447 WP_021853458.1 565 566 yes 1891315 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 400946, 1261130 Wohlfahrtiimonas chitiniclastica, Wohlfahrtiimonas chitiniclastica SH04 Bacteria UP000011617 495590919, 444508081 ELV08254.1 WP_008315498.1 fig|1261130.3.peg.926, fig|1123502.3.peg.1410 591 591 yes 1891316 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 718252 Faecalibacterium prausnitzii L2-6 Bacteria UP000008804 295102386 435 436 yes 1891317 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 883125 Klebsiella oxytoca, Klebsiella oxytoca 10-5250 Bacteria UP000030350, UP000005046 490229253, 376396784 EHT09423.1 WP_004127600.1 fig|883125.3.peg.3304 626 631 yes 1891318 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630 Yersinia enterocolitica Bacteria UP000029427 517910038 WP_019080246.1 635 670 yes 1891319 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 395568, 1125747 Glaciecola agarilytica, Glaciecola agarilytica NO2 Bacteria UP000008372 495581583, 410132090 WP_008306162.1 fig|1125747.3.peg.4361 620 626 yes 1891320 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 1036735 Bifidobacterium breve, Bifidobacterium breve 26M2 Bacteria UP000029049, UP000003804 489930123, 376165696 EHS84639.1 WP_003833445.1 fig|1036735.3.peg.1914 634 917 yes 1891321 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144327 Pseudomonas sp. GM25 Bacteria UP000007510 495227455, 398140387 EJM29349.1 WP_007952226.1 fig|1144327.3.peg.1364 628 629 yes 1891322 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 480, 857572 Moraxella catarrhalis, Moraxella catarrhalis B508 Bacteria UP000058148, UP000023796 490595877, 696614354, 672769105, 326575509 AIT42517.1, AIK00986.1, EGE25434.1 WP_004460897.1 fig|857572.3.peg.737 618 623 yes 1891323 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 549 Pantoea agglomerans Bacteria UP000050560 498358068, 610924559 EZI32743.1 WP_010672224.1 632 640 yes 1891324 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43776, 1230451 Haloarcula argentinensis, Haloarcula argentinensis DSM 12282 Archaea 491677877, 445773230 EMA24263.1 WP_005534019.1 M0KTJ7 M0KTJ7_HALAR 455 480 yes 1891325 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 225324, 553217 Enhydrobacter aerosaccus, Enhydrobacter aerosaccus SK60 Bacteria UP000053900, UP000010294 494180868, 257447472 EEV22477.1 WP_007116599.1 fig|553217.3.peg.1666 662 672 yes 1891326 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56877, 1002804 Helicobacter bizzozeronii, Helicobacter bizzozeronii CIII-1 Bacteria UP000008387 503655732, 335332587 WP_013889808.1 444 446 yes 1891327 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358, 1107544 Agrobacterium tumefaciens, Agrobacterium tumefaciens 5A Bacteria UP000064781, UP000003341 489612378, 358004667 EHJ96995.1 WP_003516819.1 599 607 yes 1891328 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1229489 beta proteobacterium L13 Bacteria 516077145 WP_017507728.1 633 634 yes 1891329 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717, 698964 Corynebacterium diphtheriae, Corynebacterium diphtheriae PW8 Bacteria UP000033584, UP000007153 504075766, 372116234 AEX68704.1 WP_014309760.1 fig|698964.3.peg.23 592 599 yes 1891330 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 657308 Gordonibacter pamelaeae 7-10-1-b Bacteria UP000008805 295106854 444 446 yes 1891331 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1328404, 1438697, 1328402, 1328386, 1328399, 1328400, 1328401, 1328403, 1328409, 1328421, 1400161, 1400160, 1328411 Klebsiella pneumoniae BIDMC 10, Klebsiella pneumoniae BIDMC 54, Klebsiella pneumoniae BIDMC 7A, Klebsiella pneumoniae BWH 36, Klebsiella pneumoniae BIDMC 2A, Klebsiella pneumoniae BIDMC 4, Klebsiella pneumoniae BIDMC 5, Klebsiella pneumoniae BIDMC 7B, Klebsiella pneumoniae BIDMC 13, Klebsiella pneumoniae BIDMC 32, Klebsiella pneumoniae BIDMC 42b, Klebsiella pneumoniae BIDMC 42a, Klebsiella pneumoniae BIDMC 16 Bacteria UP000027663, UP000027552, UP000021050, UP000022817, UP000020213, UP000022278, UP000020842, UP000020857, UP000022822, UP000022553, UP000023431, UP000019840, UP000017173 655430956, 635928006, 583738339, 583665967, 583639607, 583637597, 583636847, 583625596, 583605720, 583581919, 583566588, 583557533, 550186750 KED01132.1, KDH08304.1, EWG00024.1, EWF28402.1, EWF02190.1, EWF00204.1, EWE99471.1, EWE88272.1, EWE68589.1, EWE45042.1, EWE29847.1, EWE20847.1, ERO77480.1 258 261 no 1891332 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 202747, 563040 Sulfurimonas autotrophica, Sulfurimonas autotrophica DSM 16294 Bacteria UP000007803 503092495, 306979536 ADN09571.1 WP_013327324.1 fig|563040.3.peg.1535 466 468 yes 1891333 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 629262 Pseudomonas syringae pv. japonica str. M301072PT Bacteria UP000004471 330899862 EGH31281.1 627 629 yes 1891334 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1338032 Vibrio parahaemolyticus, Vibrio parahaemolyticus O1:K33 str. CDC_K4557 Bacteria UP000028114, UP000014945 527098025, 655798690, 655796553, 655792102, 655791939, 655704053, 655700163, 523835761 KEE78927.1, KEE77129.1, KEE73264.1, KEE73125.1, KED95176.1, KED91615.1, AGQ99627.1 WP_020904441.1 640 646 yes 1891335 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1328404, 1438697, 1328402, 1328386, 1328399, 1328400, 1328401, 1328403, 1328409, 1328421, 1400161, 1400160, 1328411 Klebsiella pneumoniae BIDMC 10, Klebsiella pneumoniae BIDMC 54, Klebsiella pneumoniae BIDMC 7A, Klebsiella pneumoniae BWH 36, Klebsiella pneumoniae BIDMC 2A, Klebsiella pneumoniae BIDMC 4, Klebsiella pneumoniae BIDMC 5, Klebsiella pneumoniae BIDMC 7B, Klebsiella pneumoniae BIDMC 13, Klebsiella pneumoniae BIDMC 32, Klebsiella pneumoniae BIDMC 42b, Klebsiella pneumoniae BIDMC 42a, Klebsiella pneumoniae BIDMC 16 Bacteria UP000027663, UP000027552, UP000021050, UP000022817, UP000020213, UP000022278, UP000020842, UP000020857, UP000022822, UP000022553, UP000023431, UP000019840, UP000017173 655430955, 635928005, 583738338, 583665966, 583639606, 583637596, 583636848, 583625595, 583605719, 583581918, 583566587, 583557532, 550186749 KED01131.1, KDH08303.1, EWG00023.1, EWF28401.1, EWF02189.1, EWF00203.1, EWE99472.1, EWE88271.1, EWE68588.1, EWE45041.1, EWE29846.1, EWE20846.1, ERO77479.1 362 364 yes 1891336 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33042, 1078091, 1078090 Coprococcus sp. HPP0048, Coprococcus sp. HPP0074 Bacteria UP000014415, UP000014401 512511139, 512062343, 512055442 EPD61783.1, EPD54961.1 WP_016439849.1 fig|1078090.3.peg.2767, fig|1078091.3.peg.2621 434 435 yes 1891337 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1305738, 1305739 Mycobacterium orygis, Mycobacterium orygis 112400015 Bacteria UP000012070 489497237, 475632541 EMT37279.1 WP_003402150.1 fig|1305739.3.peg.555 544 547 yes 1891338 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 126385, 1256992, 1256987 Providencia alcalifaciens, Providencia alcalifaciens PAL-2, Providencia alcalifaciens F90-2004 Bacteria UP000021168, UP000022577 739108166, 577059646, 573508735 EUC96867.1, ETT08833.1 WP_036978308.1 623 655 yes 1891339 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 554065 Chlorella variabilis Plants UP000008141 552821425, 307105495 EFN53744.1 XP_005845846.1 374 431 no 1891340 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 936564 Klebsiella sp. AS10 Bacteria UP000020761 695769792, 576688913 EUB42159.1 WP_032692778.1 626 631 yes 1891341 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262743 Bacteroides sp. CAG:598 Environmental samples UP000017916 546360090, 523974943 WP_021847080.1 572 572 yes 1891342 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 241425, 1173022 Crinalium epipsammum, Crinalium epipsammum PCC 9333 Bacteria UP000010472 505018215, 428249444 AFZ15224.1 WP_015205317.1 fig|1173022.3.peg.4797 455 457 yes 1891343 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 436 438 yes 1891344 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1232188 Clostridium botulinum CFSAN001628 Bacteria UP000010454 428756022 EKX78610.1 fig|1232188.3.peg.3551 289 293 no 1891345 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 669 Vibrio harveyi Bacteria UP000067422 515755423 WP_017188023.1 640 646 yes 1891346 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116151 Escherichia coli, Escherichia coli P0298942.15 Bacteria UP000036210, UP000012223 485814495, 476863104 ENB56866.1 WP_001434057.1 fig|1116151.3.peg.4667 626 631 yes 1891347 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 87 87 no 1891348 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1501, 1428454 Clostridium pasteurianum, Clostridium pasteurianum NRRL B-598 Bacteria UP000018681 565894133, 564868496 ETD70638.1 WP_023973879.1 436 436 yes 1891349 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 992001, 992000, 991945 Vibrio cholerae, Vibrio cholerae HE-46, Vibrio cholerae HE-40, Vibrio cholerae HE39 Bacteria UP000028983, UP000007830, UP000007982, UP000004586 445993249, 408666590, 408662620, 340044014 EKL37373.1, EKL33548.1, EGR04969.1 WP_000071104.1 fig|992000.3.peg.683, fig|991945.6.peg.83, fig|992001.3.peg.685 639 645 yes 1891350 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666 Vibrio cholerae Bacteria UP000028983 445993248, 669384903, 669380834, 669376796, 669357842, 811504451 KFE11055.1, KFE07507.1, KFE03981.1, KFD87191.1 WP_000071103.1 639 645 yes 1891351 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2186 Methanothermococcus thermolithotrophicus Archaea 516898069 WP_018154366.1 426 426 yes 1891352 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 991934, 992009, 991978, 991971, 991949, 991943, 991977, 992005, 991972, 991937, 992004, 991975, 991970, 991973, 991969, 991967, 991948 Vibrio cholerae, Vibrio cholerae HC-36A1, Vibrio cholerae HC-78A1, Vibrio cholerae HC-59B1, Vibrio cholerae HC-55B2, Vibrio cholerae HC-02C1, Vibrio cholerae HC-61A2, Vibrio cholerae HC-59A1, Vibrio cholerae HC-60A1, Vibrio cholerae HC-55C2, Vibrio cholerae HC-1A2, Vibrio cholerae HC-51A1, Vibrio cholerae HC-57A1, Vibrio cholerae HC-55A1, Vibrio cholerae HC-56A1, Vibrio cholerae HC-52A1, Vibrio cholerae HC-50A1, Vibrio cholerae HC-02A1 Bacteria UP000028983, UP000017121, UP000010421, UP000008376, UP000008486, UP000008375, UP000007994, UP000007991, UP000007826, UP000007984, UP000007833, UP000006781, UP000007562, UP000007378, UP000007377, UP000007563, UP000007124, UP000003149 445993243, 550388416, 443455597, 408871409, 408862822, 408855476, 408652579, 408646272, 408645087, 408637338, 408624519, 408060003, 408038585, 408028653, 408028347, 408023260, 408017521, 341641917 ERP70798.1, ELT19361.1, EKM10649.1, EKM02323.1, EKL95177.1, EKL23789.1, EKL17886.1, EKL16753.1, EKL09400.1, EKK97463.1, EKG94728.1, EKG74919.1, EKG65525.1, EKG65249.1, EKG60438.1, EKG55017.1, EGS66431.1 WP_000071098.1 fig|992004.3.peg.773, fig|992005.3.peg.852, fig|991943.3.peg.157, fig|991969.3.peg.828, fig|991977.3.peg.864, fig|991972.3.peg.773, fig|991949.3.peg.76, fig|991978.3.peg.76, fig|991973.3.peg.143, fig|992009.4.peg.751, fig|991970.3.peg.141, fig|991948.6.peg.145, fig|991971.3.peg.646, fig|991937.4.peg.88, fig|991975.3.peg.769, fig|991967.3.peg.72 639 645 yes 1891353 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 992002, 991941, 1051362, 991939 Vibrio cholerae, Vibrio cholerae HC-44C1, Vibrio cholerae HC-46B1, Vibrio cholerae HC-41B1, Vibrio cholerae HC-43B1 Bacteria UP000028983, UP000008491, UP000008374, UP000007824, UP000000705 445993242, 669388920, 408868073, 408859445, 408632452, 395947219, 811520057, 811514079, 808161586 KFE14541.1, EKM07418.1, EKL99103.1, EKL04903.1, EJH57875.1 WP_000071097.1 fig|992002.3.peg.97, fig|1051362.3.peg.97, fig|991941.3.peg.98, fig|991939.3.peg.197 639 645 yes 1891354 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 991944 Vibrio cholerae, Vibrio cholerae HE25 Bacteria UP000028983, UP000001607 445993245, 395956792 EJH67382.1 WP_000071100.1 fig|991944.3.peg.81 639 645 yes 1891355 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 991999 Vibrio cholerae, Vibrio cholerae HE-16 Bacteria UP000028983, UP000007358 445993244, 408057162 EKG92025.1 WP_000071099.1 fig|991999.3.peg.76 639 645 yes 1891356 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 1095662, 593586 Vibrio cholerae, Vibrio cholerae O1 str. 116063, Vibrio cholerae TM 11079-80 Bacteria UP000028983, UP000012144, UP000003652 445993247, 469673505, 229342929 EMP89882.1, EEO07919.1 WP_000071102.1 fig|1055325.3.peg.2578, fig|1095662.3.peg.763, fig|593586.3.peg.344 639 645 yes 1891357 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 1197727 Pseudomonas sp. Ag1 Bacteria UP000003350 495714543, 395336202 EJF68063.1 WP_008439122.1 fig|1240676.3.peg.3806, fig|1197727.3.peg.5988 628 634 yes 1891358 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 911242 Pseudomonas sp. CFII64 Bacteria UP000014850 520796901, 515429644 EPJ77440.1 WP_020293625.1 628 629 yes 1891359 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 667019 Curvibacter putative symbiont of Hydra magnipapillata Bacteria 260222379 362 364 no 1891360 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392, 1245029, 1437442 Bacillus anthracis, Bacillus anthracis str. Carbosap, Bacillus anthracis str. 95014 Bacteria UP000034470, UP000028410, UP000021880 727183784, 756780063, 666456083, 589835478 AJM78529.1, KEY92906.1, EXJ17760.1 WP_033646039.1 586 586 yes 1891361 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29530 Cytophaga aurantiaca Bacteria 517154020 WP_018342838.1 629 630 yes 1891362 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 337 Burkholderia glumae Bacteria UP000030878 515994729 WP_017425312.1 198 198 no 1891363 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116183, 1116182, 1116158, 1116039, 1116008, 1116010, 1116030, 1116112 Escherichia coli, Escherichia coli P0304816.7, Escherichia coli P0304816.6, Escherichia coli P0302308.10, Escherichia coli P0299438.4, Escherichia coli 2735000, Escherichia coli 2747800, Escherichia coli 2866750, Escherichia coli BCE002_MS12 Bacteria UP000036210, UP000012228, UP000012400, UP000012438, UP000012206, UP000012293, UP000012208, UP000012214, UP000012405 485865390, 477288104, 477274373, 477010272, 476908967, 476656581, 476251755, 476148082, 476106824 ENF59521.1, ENF46455.1, ENC95778.1, ENB99137.1, EMZ62707.1, EMW70578.1, EMV69898.1, EMV29809.1 WP_001463848.1 fig|1116039.3.peg.4548, fig|1116010.3.peg.4317, fig|1116182.3.peg.4727, fig|1116112.3.peg.4371, fig|1116030.3.peg.4475, fig|1116183.3.peg.4380, fig|1116158.3.peg.4354, fig|1116008.3.peg.4374 626 631 yes 1891364 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144325 Pseudomonas sp. GM21 Bacteria UP000007292 495222215, 398126793 EJM16218.1 WP_007946989.1 fig|1144325.3.peg.3822 627 629 yes 1891365 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 322095 Porphyromonas somerae Bacteria 516661943 WP_018028296.1 523 523 yes 1891366 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43662, 1117317 Pseudoalteromonas piscicida, Pseudoalteromonas piscicida JCM 20779 Bacteria UP000033599, UP000016521 498054671, 540273206 ERG33119.1 WP_010368827.1 645 650 yes 1891367 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47877, 53707, 629260 Pseudomonas amygdali, Pseudomonas syringae pv. lachrymans, Pseudomonas syringae pv. lachrymans str. M301315 Bacteria UP000050412, UP000037821, UP000006426 492086506, 821155458, 330984590 KKY59986.1, EGH82693.1 WP_005743016.1 627 629 yes 1891368 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1008, 694433 Saprospira grandis, Saprospira grandis DSM 2844 Bacteria UP000005113 488736013, 395320811 EJF53732.1 WP_002659412.1 623 623 yes 1891369 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935587 Neisseria meningitidis M6190 Bacteria UP000003694 325131284 EGC53995.1 fig|1145148.3.peg.2595, fig|1095688.3.peg.2733, fig|1145145.3.peg.2664, fig|1145173.3.peg.661, fig|768485.3.peg.1606, fig|1095683.3.peg.2653, fig|1145147.3.peg.2442, fig|768484.3.peg.675, fig|1145179.3.peg.2624, fig|1145154.3.peg.2599, fig|1095687.3.peg.2609, fig|272831.7.peg.2527, fig|1145172.3.peg.1567, fig|1145165.3.peg.2599, fig|1145163.3.peg.2642, fig|1145169.3.peg.2543, fig|1145146.3.peg.2627, fig|1145149.3.peg.2537, fig|935587.3.peg.2617, fig|935586.3.peg.2613, fig|1145151.3.peg.2226, fig|1095686.3.peg.2652, fig|1145164.3.peg.2571, fig|1145153.3.peg.2646, fig|1145155.3.peg.2544, fig|1145166.3.peg.2616, fig|1095684.3.peg.2602, fig|1145175.3.peg.2664, fig|1095685.3.peg.2624, fig|1145174.3.peg.2611, fig|1145152.3.peg.1714, fig|1145170.3.peg.1723, fig|1145156.3.peg.2568 625 671 yes 1891370 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 291331 Xanthomonas oryzae pv. oryzae KACC10331 Bacteria UP000006735 58425164 AAW74201.1 Q5H4C0 THIC_XANOR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 3990706, 1923491, 5516284, 953037 fig|291331.3.peg.947 572 573 yes 1891371 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28080, 306264 Campylobacter upsaliensis, Campylobacter upsaliensis RM3195 Bacteria UP000003335 490399674, 57016958 EAL53740.1 WP_004275070.1 fig|306264.1.peg.398 432 432 yes 1891372 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34037, 1151116, 741091 Rahnella aquatilis HX2, Rahnella sp. Y9602 Bacteria UP000007594, UP000007257 503342741, 380756011, 321170015 AFE60402.1, ADW75714.1 WP_013577402.1 fig|1151116.3.peg.4204, fig|741091.3.peg.4111 634 654 yes 1891373 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444252, 1116189, 1116128 Escherichia coli, Escherichia coli 3-373-03_S4_C2, Escherichia coli P0304816.13, Escherichia coli 2851500 Bacteria UP000036210, UP000027892, UP000012210, UP000012209 486435861, 650110617, 477264119, 476176377 KDU31063.1, ENF36686.1, EMV97399.1 WP_001617767.1 fig|1116128.3.peg.4577, fig|1116189.3.peg.4300 626 631 yes 1891374 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1912, 1203460, 1133850 Streptomyces hygroscopicus, Streptomyces hygroscopicus subsp. jinggangensis TL01, Streptomyces hygroscopicus subsp. jinggangensis 5008 Bacteria UP000011847, UP000007170 504486625, 451794519, 374101526 AGF64568.1, AEY90410.1 WP_014673727.1 fig|1203460.3.peg.5089 598 600 yes 1891375 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204, 553219 Campylobacter showae, Campylobacter showae RM3277 Bacteria UP000003107 490450680, 255300040 EET79317.1 WP_004321563.1 fig|553219.3.peg.1562 443 444 yes 1891376 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1056512 Grimontia sp. AK16 Bacteria UP000011223 488498158, 486370676 EOD77694.1 WP_002541600.1 637 637 yes 1891377 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 193, 862719 Azospirillum lipoferum, Azospirillum lipoferum 4B Bacteria UP000005667 504012840, 357422932 WP_014246834.1 fig|862719.3.peg.329 573 574 yes 1891378 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287275 Mesorhizobium sp. LNJC395A00 Bacteria UP000023495 563537330, 563085938 ESY10621.1 WP_023743461.1 596 611 yes 1891379 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 397288 Lachnospiraceae bacterium 3-1 Bacteria UP000014188 511034973, 507762840 EOS21539.1 WP_016289041.1 433 434 yes 1891380 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 516567972 WP_017943038.1 627 629 yes 1891381 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469597, 1262853 Coprobacillus sp. 8_2_54BFAA, Coprobacillus sp. CAG:183 Bacteria, Environmental samples UP000005559, UP000017960 496068206, 373913261, 524161570 EHQ45099.1 WP_008792713.1 fig|469597.3.peg.2994 435 435 yes 1891382 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 667126, 1069083 Methanocaldococcus sp. KIN24-T80, Methanocaldococcus villosus KIN24-T80 Archaea UP000053695 490728592, 478431945 ENN96273.1 WP_004590994.1 N6V1V4 N6V1V4_9EURY 425 425 yes 1891383 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 971, 927704 Selenomonas ruminantium, Selenomonas ruminantium subsp. lactilytica TAM6421 Bacteria UP000007887 504237507, 381366346 WP_014424609.1 437 437 yes 1891384 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 754476 Methylophaga sp. JAM1 Bacteria UP000009144 386275022 AFI84920.1 fig|754476.3.peg.2083 600 603 yes 1891385 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 1385942 Bifidobacterium breve, Bifidobacterium breve 689b Bacteria UP000029049, UP000019321 644561674, 585134870 AHJ23339.1 WP_025332374.1 636 918 yes 1891386 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 60847, 469382 Halogeometricum borinquense, Halogeometricum borinquense DSM 11551 Archaea UP000006663 492945557, 313126241, 445575134, 312292606 ELY29613.1, ADQ67066.1 WP_006054298.1, YP_004036511.1 E4NTL4 E4NTL4_HALBP 455 484 yes 1891387 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 712437, 1227272 Porphyromonas sp. oral taxon 278, Porphyromonas sp. oral taxon 278 str. W7784 Bacteria UP000016628 545427914, 543959676 ERJ69693.1 WP_021666277.1 606 608 yes 1891388 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1392499, 1049565, 1379689, 1226680 Klebsiella pneumoniae, Klebsiella pneumoniae 1158, Klebsiella pneumoniae KCTC 2242, Klebsiella pneumoniae T69, Klebsiella pneumoniae subsp. pneumoniae Ecl8 Bacteria UP000036212, UP000031116, UP000008890, UP000019181, UP000009316 491040255, 743574144, 727657349, 672603617, 339764617, 573044226, 414710767 AJC06873.1, KHF52749.1, AIJ42591.1, AEK00838.1 WP_004901924.1 fig|1226680.3.peg.5090, fig|1074486.3.peg.2394, fig|1049565.4.peg.4985 626 631 yes 1891389 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 572 580 yes 1891390 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 428994, 1346790 Sphingobium sp. HDIP04, Sphingobium chinhatense IP26 Bacteria UP000015528, UP000019104 530257605, 523385065 EQB00360.1, EPR18756.1 603 610 yes 1891391 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280941 Hyphomonas sp. T16B2 Bacteria UP000027006 736824815, 630769032 KCZ50925.1 WP_034826419.1 623 631 yes 1891392 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262980 Veillonella sp. CAG:933 Environmental samples UP000018347 546351209, 523970563 WP_021842361.1 451 451 yes 1891393 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1080712 Methanomassiliicoccus luminyensis Archaea 518008227 WP_019178435.1 416 420 yes 1891394 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 86, 1280952 Hyphomonas jannaschiana, Hyphomonas jannaschiana VP2 Bacteria UP000024816 737613712, 630937526 KCZ83867.1 WP_035584351.1 647 647 yes 1891395 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1297570 Mesorhizobium sp. STM 4661 Bacteria UP000012181 493377734, 474660532 WP_006334018.1 fig|1297570.3.peg.3876 597 611 yes 1891396 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53344 Staphylococcus delphini Bacteria 517996854 WP_019167062.1 578 578 yes 1891397 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 457390 Bacteroides sp. 3_1_23 Bacteria UP000003808 495923569, 298516603 EFI40484.1 WP_008648148.1 565 565 yes 1891398 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 118000, 522772 Denitrovibrio acetiphilus, Denitrovibrio acetiphilus DSM 12809 Bacteria UP000002012 502777250, 290886041 ADD69741.1 WP_013012226.1 fig|522772.5.peg.2191 423 423 yes 1891399 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2173 Methanobrevibacter smithii Archaea 518094428 WP_019264636.1 432 432 yes 1891400 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 866790 Methanothermobacter thermautotrophicus CaT2 Archaea UP000031654 427189938 T2GJB4 T2GJB4_9EURY 430 430 yes 1891401 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 202956, 1120929 Acinetobacter towneri, Acinetobacter towneri DSM 14962 = CIP 107472 Bacteria UP000023781 491117275, 480028490 ENV68904.1 WP_004975730.1 fig|1120929.3.peg.2256 626 631 yes 1891402 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53335, 553, 1332074, 706191, 1123863, 932677 Pantoea ananatis, Pantoea ananatis BRT175, Pantoea ananatis LMG 20103, Pantoea ananatis LMG 5342, Pantoea ananatis AJ13355 Bacteria UP000029850, UP000017028, UP000001702, UP000007861, UP000006690 502789144, 696218224, 548614731, 291150802, 365188649, 327396038 KGL57040.1, ERM13728.1, ADD75386.1 WP_013024120.1 fig|553.3.peg.4236, fig|706191.3.peg.232, fig|932677.3.peg.3896, fig|95608.3.peg.200 632 640 yes 1891403 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469608 Klebsiella sp. 1_1_55 Bacteria UP000010315 496083488, 289774315 EFD82322.1 WP_008807995.1 626 631 yes 1891404 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 75105, 1323664 Burkholderia caribensis, Burkholderia caribensis MBA4 Bacteria UP000056249, UP000019146 738031590, 575858833 ETY78069.1 WP_035990500.1 642 643 yes 1891405 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 641 684 yes 1891406 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 749953 Salmonella enterica, Salmonella enterica subsp. enterica serovar Montevideo str. ATCC BAA710 Bacteria UP000054489, UP000006202 446030580, 363559208 EHL43382.1 WP_000108435.1 fig|749953.3.peg.2535 626 631 yes 1891407 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 13690 Sphingobium yanoikuyae Bacteria UP000028534 498021322 WP_010335478.1 624 631 yes 1891408 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 300, 1197721 Pseudomonas mendocina, Pseudomonas mendocina DLHK Bacteria UP000028008, UP000006491 489339366, 400343695 EJO92067.1 WP_003246559.1 fig|1197721.3.peg.3689 627 627 yes 1891409 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262755 Blautia sp. CAG:237 Environmental samples UP000017983 547805971, 524430465 WP_022215358.1 436 436 yes 1891410 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 149 202 no 1891411 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 980584 Flavobacteriaceae bacterium HQM9 Bacteria 498208848 WP_010523004.1 620 620 yes 1891412 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 454154, 762968 Paraprevotella clara, Paraprevotella clara YIT 11840 Bacteria UP000003598 495896936, 355529734 EHG99159.1 WP_008621515.1 fig|706436.3.peg.2699, fig|762968.3.peg.2461 574 575 yes 1891413 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1637510, 1263090 Odoribacter sp. N54.MGS-14, Odoribacter splanchnicus CAG:14 Bacteria, Environmental samples UP000018252 547747123, 524354003 WP_022160309.1 585 585 yes 1891414 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294, 1038924 Pseudomonas fluorescens, Pseudomonas fluorescens SS101 Bacteria UP000060991, UP000003213 489280375, 388001406 EIK62735.1 WP_003188018.1 629 631 yes 1891415 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40214, 1217662 Acinetobacter johnsonii, Acinetobacter johnsonii ANC 3681 Bacteria UP000053042, UP000018444 491120165, 480034009 ENV73982.1 WP_004978606.1 fig|1217662.4.peg.501 627 630 yes 1891416 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 86661, 1396, 222523 Bacillus cereus, Bacillus cereus ATCC 10987 Bacteria UP000036076, UP000002527 446737218, 859607790, 42740318, 47606071 KMQ29085.1, AAS44241.1 WP_000814474.1 P61423 THIC_BACC1 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 648644 fig|1126681.3.peg.1752, fig|222523.1.peg.5305 586 586 yes 1891417 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469616 Fusobacterium mortiferum ATCC 9817 Bacteria UP000003415 340562189 EEO36131.2 441 458 yes 1891418 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28197, 944546 Arcobacter butzleri, Arcobacter butzleri ED-1 Bacteria UP000009194 504280884, 345468382 WP_014467986.1 fig|944546.4.peg.116 448 450 yes 1891419 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 118161 Pleurocapsa sp. PCC 7319 Bacteria 518334356 WP_019504563.1 459 460 yes 1891420 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33069, 450396 Pseudomonas viridiflava, Pseudomonas viridiflava UASWS0038 Bacteria UP000049942, UP000006332 491021784, 409760816 EKN45933.1 WP_004883483.1 fig|450396.6.peg.2762 627 629 yes 1891421 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42234 Streptomyces acidiscabies Bacteria UP000037151 498039957 WP_010354113.1 588 590 yes 1891422 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1385625 uncultured Thiohalocapsa sp. PB-PSB1 Environmental samples UP000017935 557399338, 557040205 ESQ16747.1 WP_023410068.1 368 368 yes 1891423 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262852 Collinsella sp. CAG:398 Environmental samples UP000018185 547948963, 524630489 WP_022349849.1 452 455 yes 1891424 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 370323, 1230457 Haloterrigena limicola, Haloterrigena limicola JCM 13563 Archaea 495284696, 445672659 ELZ25230.1 WP_008009450.1 M0CPN7 M0CPN7_9EURY 436 465 yes 1891425 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 587, 521000 Providencia rettgeri, Providencia rettgeri DSM 1131 Bacteria UP000054201, UP000003321 490385005, 291311467 EFE51920.1 WP_004264507.1 628 662 yes 1891426 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116115 Escherichia coli, Escherichia coli BCE019_MS-13 Bacteria UP000036210, UP000012360 487483940, 476112012 EMV34871.1 WP_001699482.1 fig|1116115.3.peg.4438 626 631 yes 1891427 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 64602, 29540 Natrialba asiatica, halophilic archaeon 172P1 Archaea 493049612, 445646190 ELY99179.1 WP_006110073.1 M0AKV1 M0AKV1_NATA1 456 464 yes 1891428 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 158899, 1005048 Collimonas fungivorans, Collimonas fungivorans Ter331 Bacteria UP000008392 503770628, 340551174 AEK60549.1 WP_014004704.1 639 640 yes 1891429 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1331258 Bordetella hinzii 8-296-03 Bacteria UP000025372 759485967, 849066694 KMM26530.1 WP_043206892.1 636 637 yes 1891430 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 406101 Asaia sp. SF2.1 Bacteria UP000018697 564617543 ETC99733.1 606 612 yes 1891431 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 549, 1332072 Pantoea agglomerans, Pantoea agglomerans Tx10 Bacteria UP000050560, UP000017021 550542889, 548609973 ERM09260.1 WP_022624881.1 632 640 yes 1891432 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 754523 Rhizobium leguminosarum bv. trifolii WSM1689 Bacteria UP000019020 573471174 AHF88053.1 324 325 no 1891433 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262751 Bacteroides sp. CAG:770 Environmental samples UP000018390 547880147, 524530578 WP_022285613.1 563 564 yes 1891434 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81682, 887061, 582744 Methylovorus sp. MP688, Methylovorus sp. SIP3-4 Bacteria UP000007036, UP000002743 503208658, 312441591, 253986997 ADQ85697.1, ACT51854.1 WP_013443319.1 fig|582744.3.peg.2536, fig|887061.3.peg.2469 624 627 yes 1891435 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28114 Porphyromonas levii Bacteria 517168783 WP_018357601.1 522 522 yes 1891436 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1227349 Paenibacillus sp. FSL H7-689 Bacteria UP000019061 573547944 ETT46796.1 596 605 yes 1891437 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 555793 Novosphingobium sp. Rr 2-17 Bacteria UP000004732 496284095, 392720759 EIZ78232.1 WP_008996133.1 fig|555793.3.peg.3146 618 624 yes 1891438 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454002 Candidatus Accumulibacter sp. BA-91 Bacteria UP000020077 736918999, 668677023 KFB71531.1 WP_034916618.1 638 638 yes 1891439 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 929506 Clostridium botulinum BKT015925 Bacteria UP000007806 329126594 AEB76539.1 fig|929507.3.peg.338, fig|929506.3.peg.2185, fig|929508.3.peg.1620 431 431 yes 1891440 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1182701 Escherichia coli, Escherichia coli KTE102 Bacteria UP000036210, UP000014213 510923318, 508443773 EOW13740.1 WP_016244103.1 fig|1182701.3.peg.932 626 631 yes 1891441 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 58343 Streptomyces canus Bacteria UP000053669 518963659 WP_020119534.1 599 601 yes 1891442 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294 Pseudomonas fluorescens Bacteria UP000060991 515542566 WP_016975619.1 628 629 yes 1891443 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1349820 Arthrobacter sp. AK-YN10 Bacteria UP000031809 545107718, 542110168 ERI39103.1 WP_021470804.1 594 610 yes 1891444 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 155975 Actinokineospora enzanensis Bacteria 517512297 WP_018682505.1 547 550 yes 1891445 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543913 beta proteobacterium CB Bacteria UP000011764 455440522 AGG33460.1 641 645 yes 1891446 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53335, 712898 Pantoea vagans C9-1 Bacteria UP000006631 503125078, 308059424 ADO11596.1 WP_013359739.1 fig|712898.3.peg.3621 631 640 yes 1891447 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 244365 Methylohalobius crimeensis Bacteria 551329876 WP_022949319.1 616 617 yes 1891448 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935597 Neisseria meningitidis CU385 Bacteria UP000003877 325139362 EGC61902.1 fig|935597.3.peg.2361 628 729 yes 1891449 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2746, 768066 Halomonas elongata, Halomonas elongata DSM 2581 Bacteria UP000008707 503098101, 307217762 WP_013332904.1 fig|768066.3.peg.2308 629 629 yes 1891450 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573 Klebsiella pneumoniae Bacteria UP000036212 515513386 WP_016946640.1 626 631 yes 1891451 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46469 Orenia marismortui Bacteria 517058611 WP_018247429.1 427 427 yes 1891452 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 497727, 1237085 Candidatus Nitrososphaera gargensis, Candidatus Nitrososphaera gargensis Ga9.2 Archaea UP000008037 504831064, 408403294, 408363890 AFU57620.1 WP_015018166.1, YP_006861277.1 K0ID82 K0ID82_NITGG 445 448 yes 1891453 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413888, 632292 Caldicellulosiruptor hydrothermalis, Caldicellulosiruptor hydrothermalis 108 Bacteria UP000006890 503169460, 311778493 ADQ07979.1 WP_013404121.1 fig|632292.3.peg.2383 419 421 yes 1891454 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65058, 945711 Corynebacterium ulcerans, Corynebacterium ulcerans 809 Bacteria UP000029905, UP000008886 504338849, 334697148 AEG81945.1 WP_014525951.1 fig|945711.3.peg.1471 558 569 yes 1891455 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116190 Escherichia coli, Escherichia coli P0304816.14 Bacteria UP000036210, UP000012357 490003152, 477258045 ENF30879.1 WP_003906070.1 fig|1116190.3.peg.4602 626 631 yes 1891456 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305, 1333539, 1262456 Ralstonia solanacearum, Ralstonia solanacearum SD54, Ralstonia solanacearum FQY_4 Bacteria UP000029286, UP000017823, UP000011880 515097579, 557810350, 469772452 ESS51122.1, AGH82642.1 WP_016726792.1 fig|1130829.4.peg.2467, fig|1262456.3.peg.121 629 631 yes 1891457 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 582, 1411647 Morganella morganii, Morganella morganii IS15 Bacteria UP000037663, UP000019195 738474894, 571171465 WP_036425215.1 620 649 yes 1891458 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 911045 Pseudovibrio sp. FO-BEG1 Bacteria UP000005634 504049764, 359342049 AEV35423.1 WP_014283758.1 594 599 yes 1891459 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 24, 399804 Shewanella putrefaciens, Shewanella putrefaciens 200 Bacteria UP000008209 504423505, 319426450 ADV54524.1 WP_014610607.1 fig|399804.3.peg.1914 659 716 yes 1891460 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1322, 658083, 1262983 Blautia hansenii, Lachnospiraceae bacterium 6_1_63FAA, Lachnospiraceae bacterium CAG:364 Bacteria, Environmental samples UP000004368, UP000017986 496540945, 330403792, 524466905 EGG83344.1 WP_009247093.1 435 435 yes 1891461 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632, 992159 Yersinia pestis, Yersinia pestis PY-58 Bacteria UP000000815 UP000031825, UP000005994 488353237, 391591893 EIS36402.1 WP_002422622.1 fig|992173.3.peg.4071, fig|992157.3.peg.3912, fig|992167.3.peg.3761, fig|992159.3.peg.3720, fig|992133.3.peg.4185, fig|992146.3.peg.4076, fig|992147.3.peg.4083, fig|992170.3.peg.4053, fig|992171.3.peg.4041, fig|992174.3.peg.3910, fig|992139.3.peg.4156, fig|992166.3.peg.3685, fig|992160.3.peg.3896, fig|992178.3.peg.4106, fig|992162.3.peg.3907, fig|992136.3.peg.3935, fig|992185.3.peg.3774, fig|992150.3.peg.3812, fig|992176.3.peg.3875, fig|992154.3.peg.3836, fig|992137.3.peg.4106, fig|992177.3.peg.4111, fig|992145.3.peg.4172, fig|992149.3.peg.4129, fig|992144.3.peg.3952 442 455 yes 1891462 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29430, 707232 Acinetobacter haemolyticus, Acinetobacter haemolyticus ATCC 19194 Bacteria UP000003085 490775420, 292825140 EFF83895.1 WP_004637614.1 626 631 yes 1891463 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 395922, 583355 Coraliomargarita akajimensis, Coraliomargarita akajimensis DSM 45221 Bacteria UP000000925 502809453, 293615552 ADE55707.1 WP_013044429.1 fig|583355.3.peg.2673 639 641 yes 1891464 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1049971, 1049972 Leptospira licerasiae str. MMD4847, Leptospira licerasiae serovar Varillal str. VAR 010 Bacteria UP000018720, UP000004889 404274149, 384113417 EJZ41468.1, EID99682.1 fig|1049972.3.peg.3789, fig|1049971.3.peg.2305, fig|996808.3.peg.3779 529 529 yes 1891465 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 52766, 632516 Caldicellulosiruptor lactoaceticus, Caldicellulosiruptor lactoaceticus 6A Bacteria UP000009257 503809120, 343965451 AEM74598.1 WP_014043114.1 418 420 yes 1891466 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1227352 Paenibacillus sp. FSL R7-277 Bacteria UP000019051 738836559, 573573509 ETT71997.1 WP_036726254.1 562 563 yes 1891467 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29362, 1330534 Clostridium papyrosolvens, Clostridium papyrosolvens C7 Bacteria UP000016860 523696090, 523378778 EPR13128.1 WP_020814464.1 436 436 yes 1891468 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 643473 Microchaete sp. PCC 7126 Bacteria 516249698 WP_017653661.1 458 459 yes 1891469 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630 Yersinia enterocolitica Bacteria UP000029427 517914212 WP_019084420.1 635 670 yes 1891470 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053231 Bacillus cereus, Bacillus cereus VD118 Bacteria UP000036076, UP000014019 507034950, 500450973 EOP63494.1 WP_016106647.1 fig|1053231.3.peg.5546 586 586 yes 1891471 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913082 Salmonella enterica subsp. enterica serovar Senftenberg str. A4-543 Bacteria UP000005065 353635289 EHC81642.1 fig|913082.3.peg.4095 89 91 no 1891472 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 232363 Synechococcus sp. CB0205 Bacteria 497999938 WP_010314094.1 459 461 yes 1891473 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 184917, 573370 Desulfovibrio magneticus, Desulfovibrio magneticus RS-1 Bacteria UP000009071 506342057, 239797633 WP_015861776.1 fig|573370.3.peg.3000 427 437 yes 1891474 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53399, 582899 Hyphomicrobium denitrificans, Hyphomicrobium denitrificans ATCC 51888 Bacteria UP000002033 502981363, 299525711 ADJ24180.1 WP_013216339.1 fig|582899.5.peg.192 626 630 yes 1891475 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197162, 639282 Deferribacter desulfuricans, Deferribacter desulfuricans SSM1 Bacteria UP000001520 502773335, 290754696 WP_013008319.1 fig|639282.3.peg.1616 424 425 yes 1891476 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 48296, 1217691 Acinetobacter genomosp. 3, Acinetobacter sp. ANC 4050 Bacteria UP000051522, UP000014024 507071659, 500627856 EOQ67566.1 WP_016142437.1 fig|1217691.3.peg.2572 621 625 yes 1891477 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 292, 1009846 Burkholderia cepacia, Burkholderia cepacia GG4 Bacteria UP000063625, UP000032866 504710434, 402248227 AFQ48681.1 WP_014897536.1 fig|1009846.3.peg.2368 642 643 yes 1891478 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 525909 Acidimicrobium ferrooxidans DSM 10331 Bacteria UP000000771 256009206 ACU54773.1 fig|525909.11.peg.1960 464 549 yes 1891479 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1177926 Bacillus sp. M 2-6 Bacteria UP000006234 388428491 EIL86288.1 fig|1076692.3.peg.1411, fig|1177926.3.peg.654 595 631 yes 1891480 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 629 637 yes 1891481 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262924 Prevotella sp. CAG:279 Environmental samples UP000018375 548217807, 524740465 WP_022437054.1 567 567 yes 1891482 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144305 Novosphingobium sp. AP12 Bacteria UP000007515 494959660, 398030632 EJL24041.1 WP_007685687.1 fig|1144305.3.peg.3724 618 624 yes 1891483 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454004 Candidatus Accumulibacter sp. BA-93 Bacteria UP000022141 759881002, 589615985 EXI87247.1 WP_043567715.1 638 638 yes 1891484 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1049789 Leptospira broomii str. 5399 Bacteria UP000015454 529316303 EQA44218.1 524 526 yes 1891485 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 1322347 Bifidobacterium longum, Bifidobacterium longum E18 Bacteria UP000028505, UP000018321 562751604, 560168596 ESV33883.1 WP_023658466.1 635 917 yes 1891486 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1220534 Methanobacterium sp. Maddingley MBC34 Archaea 410598207 EKQ52791.1 K6TYH9 K6TYH9_9EURY 126 126 no 1891487 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1291540, 1236689 Candidatus Methanomethylophilus alvus, Candidatus Methanomethylophilus alvus Mx1201 Archaea UP000012672 505318427, 477555743 AGI86383.1 WP_015505529.1 M9SK13 M9SK13_9EURY 437 441 yes 1891488 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151334 Clostridium difficile DA00165 Bacteria UP000015837 531384804 EQG76795.1 56 65 no 1891489 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632569, 882083 Saccharomonospora marina, Saccharomonospora marina XMU15 Bacteria UP000004926 496447521, 374658155 EHR52988.1 WP_009156366.1 544 548 yes 1891490 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 195, 887289 Campylobacter coli, Campylobacter coli 86119 Bacteria UP000062643, UP000005694 488892714, 380536471 EIA61099.1 WP_002803862.1 fig|887289.3.peg.1257 429 430 yes 1891491 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281237, 1281210, 1281024, 1182698, 1182681, 1182677, 1182676, 1169355, 1169354, 1169353, 1169343, 1182723, 749527 Escherichia coli, Escherichia coli UMEA 3304-1, Escherichia coli UMEA 3190-1, Escherichia coli HVH 87 (4-5977630), Escherichia coli KTE98, Escherichia coli KTE74, Escherichia coli KTE70, Escherichia coli KTE69, Escherichia coli KTE38, Escherichia coli KTE37, Escherichia coli KTE36, Escherichia coli KTE24, Escherichia coli KTE143, Escherichia coli MS 21-1 Bacteria UP000036210, UP000016253, UP000015988, UP000016034, UP000014177, UP000014110, UP000014163, UP000014092, UP000014196, UP000014194, UP000014105, UP000014165, UP000010715, UP000005688 447199685, 535746227, 535638289, 534848586, 508433484, 508413969, 508398114, 508388851, 508328715, 508314086, 508313421, 508294281, 431216497, 300456291 EQY80263.1, EQX74669.1, EQP99328.1, EOW03615.1, EOV84378.1, EOV68887.1, EOV59834.1, EOV00669.1, EOU86266.1, EOU85611.1, EOU66860.1, ELF14096.1, EFK19784.1 WP_001276941.1 fig|1182681.3.peg.4599, fig|749527.3.peg.3436, fig|1182676.3.peg.4846, fig|1169355.3.peg.4908, fig|1182723.3.peg.4645, fig|1169343.3.peg.4982, fig|1169354.3.peg.5064, fig|1182677.3.peg.4958, fig|1182698.3.peg.890, fig|1169353.3.peg.5041 626 631 yes 1891492 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1077975 Gordonia rubripertincta NBRC 101908 Bacteria UP000010744 403199379 fig|1077975.4.peg.2403 551 563 yes 1891493 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1078035, 1248823, 1446588, 1446585, 1446597, 1446586, 1446587, 1446589, 1446590, 1446591, 1446593, 1446592, 1446594, 1446595, 1446596, 1248902, 1389955 Escherichia coli, Escherichia coli O145:H28 str. 4865/96, Escherichia coli O145:H28 str. RM12581, Escherichia coli O145:NM str. 2010C-3508, Escherichia coli O145:NM str. 06-3484, Escherichia coli O145:NM str. 2010C-4557C2, Escherichia coli O145:NM str. 08-4270, Escherichia coli O145:NM str. 2010C-3507, Escherichia coli O145:NM str. 2010C-3509, Escherichia coli O145:NM str. 2010C-3510, Escherichia coli O145:NM str. 2010C-3511, Escherichia coli O145:NM str. 2010C-3517, Escherichia coli O145:NM str. 2010C-3516, Escherichia coli O145:NM str. 2010C-3518, Escherichia coli O145:NM str. 2010C-3521, Escherichia coli O145:NM str. 2010C-3526, Escherichia coli O145:H28 str. RM13514, Escherichia coli ATCC 35150 Bacteria UP000036210, UP000027030, UP000025231, UP000024195, UP000024153, UP000023802, UP000023861, UP000024302, UP000024112, UP000024125, UP000024145, UP000023975, UP000023838, UP000024183, UP000024064, UP000023924, UP000019021, UP000018859 447199686, 822924327, 788905238, 636546948, 636546193, 628080039, 607812953, 606937199, 606876692, 606647148, 606499528, 606487965, 606482682, 606481645, 606474161, 606472729, 606466977, 606457483, 606446757, 573971477, 567036790 KLG49666.1, KJW55411.1, KDM78423.1, KDM77693.1, AHY73565.1, EZE92380.1, EYZ69492.1, EYZ11909.1, EYW94860.1, EYV55309.1, EYV44099.1, EYV39023.1, EYV38065.1, EYV30933.1, EYV29587.1, EYV24044.1, EYV14864.1, EYV04580.1, AHG11742.1, ETJ68689.1 WP_001276942.1 626 631 yes 1891494 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 838, 1602172, 1602171, 1602169, 1602170, 1602168, 1262931 Prevotella sp. P5-125, Prevotella sp. P5-119, Prevotella sp. P4-76, Prevotella sp. P5-60, Prevotella sp. P4-65, Prevotella sp. CAG:592 Bacteria, Environmental samples UP000032083, UP000032046, UP000032108, UP000032121, UP000032114, UP000018343 547912859, 755256750, 755255684, 755250812, 755249578, 755249054, 524582287 KIP64403.1, KIP63394.1, KIP58722.1, KIP57535.1, KIP57048.1 WP_022315767.1 528 528 yes 1891495 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 473781 Sphingomonas sp. LH128 Bacteria UP000004402 496108454, 402259374 EJU09625.1 WP_008832961.1 fig|473781.5.peg.5481 209 215 no 1891496 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310638 Acinetobacter baumannii, Acinetobacter baumannii 1437282 Bacteria UP000028632, UP000020489 696300440, 587833916 EXB24718.1 WP_032875981.1 626 631 yes 1891497 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1381122 Rhodococcus erythropolis DN1 Bacteria UP000016045 532560197 EQM31064.1 532 543 yes 1891498 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 502790, 1268237 Aeromonas diversa, Aeromonas diversa 2478-85 Bacteria UP000023775 491496599, 480569875 ENY71711.1 WP_005354312.1 fig|1268237.3.peg.2349 662 680 yes 1891499 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 860, 469621 Fusobacterium periodonticum, Fusobacterium sp. 1_1_41FAA Bacteria UP000003964 496096824, 294480291 EFG28068.1 WP_008821331.1 433 433 yes 1891500 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 864069 Rhizobiales bacterium WSM3557 Bacteria UP000003947 497154984, 388590637 EIM30920.1 WP_009489059.1 614 616 yes 1891501 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116053 Escherichia coli, Escherichia coli P0299917.7 Bacteria UP000036210, UP000012418 485888817, 476989159 ENC75866.1 WP_001481858.1 fig|1116053.3.peg.3641 626 631 yes 1891502 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1111069 Thermus sp. CCB_US3_UF1 Bacteria UP000005635 504328640, 359290868 AEV16385.1 WP_014515742.1 fig|1111069.3.peg.1316 431 434 yes 1891503 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204039 Dickeya dianthicola Bacteria 570359969 WP_024108091.1 631 655 yes 1891504 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1194153 Salmonella enterica, Salmonella enterica subsp. enterica serovar Ohio str. CFSAN001079 Bacteria UP000054489, UP000017562 555282660, 554436322 ESJ59878.1 WP_023258446.1 626 631 yes 1891505 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 544644 Butyricimonas synergistica Bacteria 517147443 WP_018336261.1 582 582 yes 1891506 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 58135, 760568 Desulfotomaculum kuznetsovii, Desulfotomaculum kuznetsovii DSM 6115 Bacteria UP000054111, UP000009229 503587349, 333821247 AEG13910.1 WP_013821425.1 fig|760568.4.peg.313 419 424 yes 1891507 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992181 Yersinia pestis, Yersinia pestis PY-100 Bacteria UP000000815 UP000031825, UP000005172 488359665, 391710077 EIT41186.1 WP_002429050.1 179 205 no 1891508 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39777, 866778 Veillonella atypica, Veillonella atypica ACS-134-V-Col7a Bacteria UP000005942 491523560, 302515540 EFL57502.1 WP_005381187.1 434 434 yes 1891509 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 675810 Vibrio sp. RC341 Bacteria UP000004967 445993265, 260840763 EEX67312.1 WP_000071120.1 640 646 yes 1891510 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 662, 666, 756012, 671076 Vibrio cholerae, Vibrio mimicus SX-4, Vibrio mimicus VM573 Bacteria UP000028983, UP000005771, UP000003714 445993264, 669406285, 342322075, 258584576 KFE29830.1, EGU17869.1, EEW09313.1 WP_000071119.1 fig|671076.4.peg.3419, fig|756012.3.peg.3485 640 646 yes 1891511 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 674, 671074 Vibrio mimicus, Vibrio mimicus VM603 Bacteria UP000053748, UP000004827 445993263, 258581086 EEW06005.1 WP_000071118.1 fig|671074.4.peg.2829 640 646 yes 1891512 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 674, 675820 Vibrio mimicus, Vibrio mimicus VM223 Bacteria UP000053748, UP000004929 445993262, 262027985 EEY46646.1 WP_000071117.1 640 646 yes 1891513 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 674, 675806 Vibrio mimicus, Vibrio mimicus MB-451 Bacteria UP000053748, UP000004603 445993261, 261893902 EEY39888.1 WP_000071116.1 640 646 yes 1891514 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666, 345074 Vibrio cholerae, Vibrio cholerae RC385 Bacteria UP000028983, UP000004696 445993260, 297533999 EFH72839.1 WP_000071115.1 639 645 yes 1891515 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 420952 Burkholderia bryophila Bacteria 518909549 WP_020065424.1 642 643 yes 1891516 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 672, 1437872 Vibrio vulnificus, Vibrio vulnificus BAA87 Bacteria UP000054370, UP000021731 515989562, 674453143, 674449294, 674441039, 586664414 KFK68651.1, KFK65491.1, KFK58383.1, EWS67836.1 WP_017420145.1 639 647 yes 1891517 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 190893, 675814 Vibrio coralliilyticus, Vibrio coralliilyticus ATCC BAA-450 Bacteria UP000033403, UP000003067 494015172, 260608946 EEX35106.1 WP_006957532.1 640 646 yes 1891518 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 192952 Methanosarcina mazei Go1 Archaea UP000000595 20905457 AAM30721.1 Q8PY39 THIC2_METMA Phosphomethylpyrimidine synthase 2 {ECO:0000255|HAMAP-Rule:MF_00089} 248990 fig|192952.1.peg.1025 434 435 yes 1891519 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1206777 Pseudomonas syringae Lz4W Bacteria UP000011925 489534231, 459962558 EMI08533.1 WP_003438961.1 fig|1206777.3.peg.600 627 629 yes 1891520 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992179, 992161, 992132, 992131 Yersinia pestis, Yersinia pestis PY-98, Yersinia pestis PY-60, Yersinia pestis PY-06, Yersinia pestis PY-05 Bacteria UP000000815 UP000031825, UP000003219, UP000003862, UP000003318, UP000004229 488304014, 391693569, 391595477, 391441393, 391437738 EIT26306.1, EIS39520.1, EIR01885.1, EIQ98567.1 WP_002374780.1 208 227 no 1891521 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1335420 Mycobacterium avium MAV_120809_2495 Bacteria UP000021111 576363065 ETZ57366.1 438 439 yes 1891522 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 34 Myxococcus xanthus Bacteria 521967039 WP_020478644.1 311 314 no 1891523 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 1415559, 457428, 1200984 Streptomyces sp. WM6391, Streptomyces lividans TK24, Streptomyces lividans 1326 Bacteria UP000033691, UP000002769, UP000014062 490072829, 807137870, 672370796, 509519584, 289700655 KKD15511.1, AIJ14678.1, EOY48897.1, EFD68084.1 WP_003975004.1 595 606 yes 1891524 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55518, 1430440 Magnetospirillum gryphiswaldense, Magnetospirillum gryphiswaldense MSR-1 v2 Bacteria UP000018922 568203960, 566554061 WP_024078324.1 600 605 yes 1891525 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 158500 Novosphingobium resinovorum Bacteria UP000024329 738617322, 612122384 EZP80354.1 WP_036527235.1 612 624 yes 1891526 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1154758 Pseudomonas avellanae BPIC 631 Bacteria UP000006668 407987466 EKG30261.1 fig|1154758.3.peg.4572 628 630 yes 1891527 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 223283, 251701 Pseudomonas syringae pv. tomato str. DC3000, Pseudomonas syringae group genomosp. 3 Bacteria UP000002515 28872090, 499417791, 28855344, 37999554 AAO58404.1 NP_794709.1, WP_011105255.1 Q87VG1 THIC_PSESM Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 337888, 6217215 fig|223283.1.peg.4847 628 629 yes 1891528 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1418096, 1418095 Xanthomonas arboricola pv. pruni MAFF 301427, Xanthomonas arboricola pv. pruni MAFF 301420 Bacteria UP000019142, UP000019084 575395239, 573454752 584 584 yes 1891529 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 382 Sinorhizobium meliloti Bacteria UP000028953 515846459 WP_017277212.1 600 611 yes 1891530 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1075090 Gordonia amarae NBRC 15530 Bacteria UP000006023 358238201 fig|1075090.3.peg.3891 563 576 yes 1891531 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354276, 550, 1333850, 1329810, 1329815, 1329819, 1329824, 1329853 Enterobacter cloacae, Enterobacter cloacae ECNIH2, Enterobacter sp. MGH 1, Enterobacter sp. MGH 6, Enterobacter sp. MGH 10, Enterobacter sp. MGH 15, Enterobacter cloacae UCICRE 5 Bacteria UP000036177, UP000027611, UP000022799, UP000023471, UP000021936, UP000022208, UP000017280 556387497, 838680664, 829419936, 829417779, 829411846, 829391758, 829385496, 829383775, 829334815, 829267672, 828981853, 828921037, 828911881, 828897884, 771290544, 771278785, 771215088, 771194835, 771130802, 771078933, 768628589, 742979925, 662712586, 578343635, 578327330, 578320281, 578291882, 555079579 KLW64346.1, KLR10940.1, KLR08860.1, KLR03060.1, KLQ83242.1, KLQ77057.1, KLQ75408.1, KLQ27272.1, KLP66349.1, AKL54086.1, AKK98715.1, AKK90137.1, AKK77094.1, KJO25747.1, KJO14385.1, KJN56681.1, KJN42035.1, KJM94177.1, KJM56064.1, KJI61520.1, AJB60840.1, AIE62165.1, EUN02698.1, EUM86596.1, EUM79663.1, EUM51603.1, ESM23208.1 WP_023302919.1 626 631 yes 1891532 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1401027, 1341181 Flavobacterium limnosediminis, Flavobacterium limnosediminis JC2902 Bacteria UP000018004 559210745, 558901725 ESU28944.1 WP_023578635.1 607 607 yes 1891533 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 403181, 662479 Haloferax mucosum, Haloferax mucosum ATCC BAA-1512 Archaea 495594047, 445745528 ELZ96995.1 WP_008318626.1 M0IJT9 M0IJT9_9EURY 441 469 yes 1891534 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1310591 Acinetobacter baumannii 942194 Bacteria UP000020623 588117292 EXD95519.1 364 374 no 1891535 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1168065 gamma proteobacterium BDW918 Bacteria UP000003473 495527760, 385278008 EIF41981.1 WP_008252405.1 fig|1168065.3.peg.3361 627 631 yes 1891536 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1310591 Acinetobacter baumannii 942194 Bacteria UP000020623 588117291 EXD95518.1 251 251 no 1891537 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053229 Bacillus cereus, Bacillus cereus VD107 Bacteria UP000036076, UP000006998 488102846, 401242498 EJR48873.1 WP_002174243.1 fig|1053229.3.peg.4136 586 586 yes 1891538 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 29760 Vitis vinifera Plants UP000009183 UP000009183 147853036 461 515 no 1891539 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1238220 Vibrio parahaemolyticus, Vibrio parahaemolyticus VPTS-2010_2 Bacteria UP000028114, UP000024735 646551718, 823652491, 589864462 KLI83456.1, EXJ40875.1 WP_025554103.1 640 646 yes 1891540 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 134534, 1217658, 1330039, 1217657 Acinetobacter gyllenbergii, Acinetobacter gyllenbergii NIPH 230, Acinetobacter gyllenbergii MTCC 11365, Acinetobacter gyllenbergii CIP 110306 Bacteria UP000017272, UP000014546, UP000014523 514348683, 554734319, 514262756, 514095140 ESK39475.1, EPH34700.1, EPF75154.1 WP_016540820.1 fig|1217657.3.peg.3061 626 631 yes 1891541 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 431 431 yes 1891542 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1428 Bacillus thuringiensis Bacteria UP000031834 516373731 WP_017763764.1 586 586 yes 1891543 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1239292 Thioalkalivibrio sp. ALgr3 Bacteria 517698638 WP_018868846.1 627 629 yes 1891544 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 574 yes 1891545 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 889233 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni 1854 Bacteria UP000065538, UP000005965 489016983, 380665685 EIB81249.1 WP_002927500.1 fig|889233.3.peg.650 430 430 yes 1891546 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1177931 Thiovulum sp. ES Bacteria UP000005330 495627619, 394445526 EJF06427.1 WP_008352198.1 107 107 no 1891547 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144328 Pseudomonas sp. GM30 Bacteria UP000007270 495242627, 576712253 EUB84187.1 WP_007967390.1 628 629 yes 1891548 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444276, 1444111, 1444274 Escherichia coli, Escherichia coli 3-020-07_S4_C3, Escherichia coli 3-267-03_S1_C3, Escherichia coli 1-182-04_S4_C3 Bacteria UP000036210, UP000027882, UP000028033, UP000024160 693103028, 652240186, 650035339, 611010051 KDZ46579.1, KDT58498.1, EZJ14976.1 WP_032257735.1 626 631 yes 1891549 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 228 Pseudoalteromonas haloplanktis Bacteria 515078613 WP_016708395.1 645 650 yes 1891550 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1214225 Acidocella sp. MX-AZ02 Bacteria UP000006217 409129272 EKM99132.1 fig|1214225.3.peg.2317 565 569 yes 1891551 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 452 460 yes 1891552 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76113, 1348657 Thauera terpenica, Thauera terpenica 58Eu Bacteria UP000015455 544832567, 528865088 EPZ16594.1 WP_021248350.1 638 638 yes 1891553 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1208321 Marinomonas sp. D104 Bacteria UP000018857 567424898, 566042270 ETI61641.1 WP_024023090.1 647 669 yes 1891554 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469589 Bacteroides sp. 2_1_33B Bacteria UP000004708 496047672, 262296964 EEY84894.1 WP_008772179.1 565 565 yes 1891555 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413496, 1128983, 1401659, 1208591 Cronobacter malonaticus ENBT0334, Cronobacter sakazakii CMCC 45402, Cronobacter malonaticus 681 Bacteria UP000032244, UP000018545, UP000009351 495055417, 758637593, 564119878, 426293860 KIU60568.1, AHB72199.1 WP_007780253.1 626 633 yes 1891556 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 213185, 647171 Methanotorris formicicus, Methanotorris formicicus Mc-S-70 Archaea 494103924, 373559399 EHP85698.1 WP_007044711.1 H1KZQ7 H1KZQ7_9EURY 426 426 yes 1891557 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 862962 Bacteroides fragilis, Bacteroides fragilis 638R Bacteria UP000036847, UP000008560 504064996, 301163504 WP_014298990.1 fig|817.1.peg.3441, fig|862962.3.peg.2616 564 564 yes 1891558 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1116375 Vibrio sp. EJY3 Bacteria UP000006799 503999379, 369842376 AEX23520.1 WP_014233373.1 fig|1116375.3.peg.3046 640 646 yes 1891559 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 906, 1285585, 1273103 Megasphaera sp. BL7, Megasphaera sp. NM10 Bacteria UP000014880, UP000014835 520879736, 519679110, 519678335 EPP15661.1, EPP14955.1 WP_020311363.1 433 433 yes 1891560 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487316, 1217676 Acinetobacter soli, Acinetobacter soli CIP 110264 Bacteria UP000053120, UP000018450 491070680, 480017705 ENV58834.1 WP_004932304.1 fig|1217676.3.peg.91 627 631 yes 1891561 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 680 Vibrio campbellii Bacteria UP000030534 498328993 WP_010643149.1 640 646 yes 1891562 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1119528 Methyloversatilis sp. FAM1 Bacteria 519007093 WP_020162968.1 642 642 yes 1891563 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 889 Desulfovibrio longus Bacteria 550910293 WP_022663373.1 427 428 yes 1891564 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992141 Yersinia pestis, Yersinia pestis PY-15 Bacteria UP000000815 UP000031825, UP000004749 488332099, 391486812 EIR42814.1 WP_002401484.1 208 227 no 1891565 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1470347 Candidatus Alistipes marseilloanorexicus Bacteria 518075976 WP_019246184.1 507 507 yes 1891566 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1121428 Desulfotomaculum hydrothermale Lam5 = DSM 18033 Bacteria UP000009315 411454878 fig|1121428.3.peg.1365 431 432 yes 1891567 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 653685, 1054400, 1423, 1338518 Bacillus amyloliquefaciens subsp. plantarum, Bacillus subtilis, Bacillus amyloliquefaciens subsp. plantarum UCMB5033 Bacteria UP000030083, UP000015481 530662309, 756870873, 703573261, 530332803 KIR04750.1, AIW29150.1 WP_020953945.1 590 590 yes 1891568 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573 Klebsiella pneumoniae Bacteria UP000036212 802149066, 597517114 WP_046043856.1 626 631 yes 1891569 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 1396518, 457431 Streptomyces sp. HCCB10043, Streptomyces roseosporus NRRL 15998 Bacteria UP000018316, UP000003986 493081511, 559243674, 291349134 ESU49956.1, EFE76038.1 WP_006126035.1 594 596 yes 1891570 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262744 Bacteroides sp. CAG:633 Environmental samples UP000018121 547750361, 524356877 WP_022163313.1 564 564 yes 1891571 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 517550444 WP_018720652.1 530 530 yes 1891572 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116091 Escherichia coli, Escherichia coli p0305293.3 Bacteria UP000036210, UP000012389 487398159, 477390358 ENG57518.1 WP_001667998.1 fig|1116091.3.peg.4659 626 631 yes 1891573 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 598 599 yes 1891574 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1157639 Streptomyces sp. FxanaD5 Bacteria 518355131 WP_019525338.1 595 598 yes 1891575 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1491, 1407017 Clostridium botulinum, Clostridium botulinum B str. Osaka05 Bacteria UP000030128, UP000054164 662072250, 559781825 WP_030036352.1 437 437 yes 1891576 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324, 1451188 Stenotrophomonas maltophilia, Stenotrophomonas maltophilia M30 Bacteria UP000034806, UP000022920 696382067, 814590593, 635551370 KKF86536.1, KDE92083.1 WP_032955989.1 613 614 yes 1891577 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 383911 Pseudoalteromonas sp. BSi20311 Bacteria UP000005146 495390777, 358025697 WP_008115478.1 fig|383911.3.peg.3526 645 650 yes 1891578 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 509 511 no 1891579 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 110 110 no 1891580 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61858, 1227500 Natronorubrum bangense, Natronorubrum bangense JCM 10635 Archaea 492959822, 445588872 ELY43111.1 WP_006067907.1 L9W1F3 L9W1F3_9EURY 456 481 yes 1891581 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 631454 Phyllobacteriaceae bacterium AMV1 Bacteria UP000017819 557406402 ESR26479.1 606 612 yes 1891582 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 565, 1115512 Escherichia hermannii, Escherichia hermannii NBRC 105704 Bacteria UP000010297 488369227, 377538849 WP_002438612.1 fig|1115512.3.peg.4029 626 633 yes 1891583 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 490 Neisseria sicca Bacteria 518100938 WP_019271146.1 625 633 yes 1891584 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 517644561 WP_018814769.1 530 530 yes 1891585 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 517341943 WP_018517435.1 600 607 yes 1891586 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935590 Neisseria meningitidis M0579 Bacteria UP000003557 325135272 EGC57893.1 fig|935590.3.peg.2627 625 671 yes 1891587 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1681, 1207543 Bifidobacterium bifidum, Bifidobacterium bifidum IPLA 20015 Bacteria UP000035497, UP000007366 489916094, 407296999 EKF16481.1 WP_003819491.1 fig|1207543.3.peg.309 637 683 yes 1891588 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1438793, 1438785, 1438706, 1438702, 1438809, 1328424, 1328363, 1328393 Klebsiella pneumoniae, Klebsiella pneumoniae MGH-70, Klebsiella pneumoniae MGH 60, Klebsiella pneumoniae BWH 48, Klebsiella pneumoniae BIDMC 69, Klebsiella pneumoniae UCI 64, Klebsiella pneumoniae BIDMC 35, Klebsiella pneumoniae MGH 18, Klebsiella pneumoniae UCICRE 7 Bacteria UP000036212, UP000027507, UP000027573, UP000027515, UP000027542, UP000024838, UP000021462, UP000017387, UP000017534 556377583, 846726472, 839780742, 839751724, 839743789, 839575641, 719632650, 636384732, 636356753, 635979427, 635942631, 612319016, 583572382, 555204780, 555052596 KMK37727.1, KMI53543.1, KMI24720.1, KMI16926.1, KMG51042.1, AIX01934.1, KDL61944.1, KDL34195.1, KDH59436.1, KDH22874.1, EZR11413.1, EWE35592.1, ESN47144.1, ESL96844.1 WP_023302347.1 626 631 yes 1891589 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 224308 Bacillus subtilis subsp. subtilis str. 168 Bacteria UP000001570 UP000030629 29713444, 1673401 AAO99664.1 P45740 THIC_BACSU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 6132113, 37411, 6127580, 6136503 fig|224308.1.peg.878 590 590 yes 1891590 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 347 Xanthomonas oryzae Bacteria UP000037499 518130895 WP_019301103.1 624 625 yes 1891591 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 628 629 yes 1891592 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 209639 Marinobacter lipolyticus Bacteria 517216377 WP_018405195.1 629 629 yes 1891593 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992182, 992171, 992151, 992135, 992129, 992127 Yersinia pestis, Yersinia pestis PY-101, Yersinia pestis PY-89, Yersinia pestis PY-46, Yersinia pestis PY-09, Yersinia pestis PY-03, Yersinia pestis PY-01 Bacteria UP000000815 UP000031825, UP000005020, UP000004729, UP000005370, UP000005404, UP000005342, UP000004531 488284092, 391710516, 391653102, 391550204, 391455724, 391421836, 391421522 EIT41567.1, EIS90107.1, EIR99842.1, EIR14820.1, EIQ84489.1, EIQ84207.1 WP_002355300.1 206 225 no 1891594 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397525 Acinetobacter sp. COS3 Bacteria UP000018430 552561357, 550675471 ERS00306.1 WP_023013648.1 626 631 yes 1891595 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1175444, 1041930 Methanocella conradii, Methanocella sp. HZ254 Archaea UP000005233 504218035, 379320346 AFC99298.1 WP_014405137.1 H8I5H9 H8I5H9_METCZ 417 432 yes 1891596 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263102 Prevotella copri CAG:164 Environmental samples UP000018361 547650132, 524307295 WP_022121899.1 563 564 yes 1891597 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1391994 Mycobacterium avium subsp. paratuberculosis 10-8425 Bacteria UP000031932 564213380 ETB46463.1 459 460 yes 1891598 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 645465 Streptomyces sp. e14 Bacteria UP000004704 292833614 EFF91963.1 592 594 yes 1891599 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47883, 96901 Pseudomonas synxantha, Pseudomonas sp. BG33R Bacteria UP000051278, UP000004740 492236488, 388007907 EIK69173.1 WP_005784175.1 628 634 yes 1891600 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43997, 592026 Catonella morbi, Catonella morbi ATCC 51271 Bacteria UP000018227 556508229, 554921531 ESL04513.1 WP_023353131.1 436 437 yes 1891601 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265494 Thioalkalivibrio sp. ALE11 Bacteria 518399159 WP_019569366.1 627 629 yes 1891602 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 61645, 550, 1560339, 1329845 Enterobacter asburiae, Enterobacter cloacae, Enterobacter sp. E20, Enterobacter cloacae BWH 31 Bacteria UP000036088, UP000036177, UP000030955, UP000017391 556425048, 829299212, 794250895, 794219989, 771382002, 768625542, 733357753, 555091833 KLP92309.1, KJX08793.1, KJW78825.1, KJP14362.1, KJI58555.1, KHK42887.1, ESM34960.1 WP_023309975.1 626 631 yes 1891603 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 246167, 1507980 Vibrio crassostreae, Vibrio sp. J2-31 Bacteria UP000049932, UP000041625 515630396, 857988787, 857958990, 857949143, 857942646, 857902183, 857894403, 857787478, 808416197, 808406216 WP_017062996.1 640 649 yes 1891604 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35742, 662476 Haloarcula sinaiiensis, Haloarcula sinaiiensis ATCC 33800 Archaea 491099195, 445762858 EMA14070.1 WP_004960796.1 M0K2J6 M0K2J6_9EURY 454 480 yes 1891605 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217714 Acinetobacter sp. ANC 3789 Bacteria UP000018452 490887956, 479934506 ENU81721.1 WP_004749910.1 fig|1217714.3.peg.333 626 631 yes 1891606 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 1218177 Streptomyces sp. GBA 94-10 Bacteria UP000017755 557420219, 556916143 ESP98788.1 WP_023422302.1 595 597 yes 1891607 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262828 Clostridium sp. CAG:62 Environmental samples UP000018137 548059265, 524664503 WP_022376587.1 435 435 yes 1891608 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28132, 553174 Prevotella melaninogenica, Prevotella melaninogenica ATCC 25845 Bacteria UP000001498 503029037, 302149174 ADK95436.1 WP_013264013.1 fig|553174.3.peg.327 525 525 yes 1891609 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 32022, 1408176, 1365660, 1365657, 1365656, 1327986, 1365655, 1295010, 889229, 889227, 889226, 889224, 889220, 889248, 889244, 889216, 1093789, 1093788, 718271, 195099 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni, Campylobacter jejuni subsp. jejuni F38011, Campylobacter jejuni Cj3, Campylobacter jejuni Cj1, Campylobacter jejuni 30318, Campylobacter jejuni 10227, Campylobacter jejuni 30286, Campylobacter jejuni subsp. jejuni HPC5, Campylobacter jejuni subsp. jejuni 87459, Campylobacter jejuni subsp. jejuni 51037, Campylobacter jejuni subsp. jejuni 1997-14, Campylobacter jejuni subsp. jejuni 1997-10, Campylobacter jejuni subsp. jejuni 53161, Campylobacter jejuni subsp. jejuni LMG 9081, Campylobacter jejuni subsp. jejuni LMG 23269, Campylobacter jejuni subsp. jejuni 51494, Campylobacter jejuni subsp. jejuni D2600, Campylobacter jejuni subsp. jejuni NW, Campylobacter jejuni subsp. jejuni S3, Campylobacter jejuni RM1221 Bacteria UP000065538, UP000032540, UP000031642, UP000024568, UP000024896, UP000024884, UP000024484, UP000024875, UP000023627, UP000005476, UP000003837, UP000003747, UP000004334, UP000003405, UP000005458, UP000004519, UP000003360, UP000005772, UP000005757, UP000006628, UP000000436 488956543, 756009794, 703557323, 631614681, 631612970, 631609029, 631605803, 631601508, 612154790, 380657430, 380654131, 380649721, 380645598, 380624425, 380621312, 380613676, 380602663, 356487947, 356485789, 315057873, 57166311, 73621976 AJK70617.1, AIW09708.1, KDA30617.1, KDA28933.1, KDA25103.1, KDA21941.1, KDA17701.1, AHW91493.1, EIB73502.1, EIB70507.1, EIB66409.1, EIB62626.1, EIB43077.1, EIB40123.1, EIB33146.1, EIB22914.1, EHI17885.1, EHI15777.1, ADT72202.1, AAW35090.1 WP_002867618.1 Q5HW14 THIC_CAMJR Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 833961, 2736413, 2749910 fig|889227.3.peg.769, fig|889229.3.peg.1195, fig|195099.3.peg.1010, fig|889216.3.peg.157, fig|889244.3.peg.68, fig|889248.3.peg.852, fig|889226.3.peg.833, fig|1093789.3.peg.460, fig|718271.4.peg.443, fig|889220.3.peg.304, fig|1093788.3.peg.969, fig|889224.3.peg.1184 430 430 yes 1891610 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1764, 1391993 Mycobacterium avium, Mycobacterium avium subsp. paratuberculosis 11-1786 Bacteria UP000029534 565059135, 564197592 ETB34617.1 WP_023883713.1 465 466 yes 1891611 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305 Ralstonia solanacearum Bacteria UP000029286 518547154 WP_019717361.1 629 631 yes 1891612 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 907, 1064535 Megasphaera elsdenii, Megasphaera elsdenii DSM 20460 Bacteria UP000029696, UP000010111 503782549, 341822890 WP_014016543.1 433 433 yes 1891613 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630 639 yes 1891614 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 673, 675812 Grimontia hollisae, Grimontia hollisae CIP 101886 Bacteria UP000067052, UP000003604 491643499, 262222821 EEY74130.1 WP_005501027.1 637 637 yes 1891615 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310681 Acinetobacter baumannii, Acinetobacter baumannii 1542444 Bacteria UP000028632, UP000021049 691062395, 588184219 EXE57935.1 WP_032005848.1 621 625 yes 1891616 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 382, 1230587 Sinorhizobium meliloti, Sinorhizobium meliloti Rm41 Bacteria UP000028953, UP000006184 504820990, 801177295, 407322862 KKA14960.1 WP_015008092.1 fig|1230587.3.peg.5720 601 611 yes 1891617 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396859 Marinobacter sp. C1S70 Bacteria UP000017125 550789707 ERS87487.1 585 585 yes 1891618 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28187, 574087 Acetohalobium arabaticum, Acetohalobium arabaticum DSM 5501 Bacteria UP000001661 503044002, 302204857 ADL13535.1 WP_013278978.1 fig|574087.3.peg.2083 427 427 yes 1891619 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 491952 Marinomonas sp. IVIA-Po-181 Bacteria UP000009230 333478330 AEF54991.1 fig|491952.3.peg.1991 639 680 yes 1891620 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59930, 292564 Cyanobium gracile, Cyanobium gracile PCC 6307 Bacteria UP000010388 504922655, 427346602 AFY29315.1 WP_015109757.1 fig|292564.3.peg.2089 458 462 yes 1891621 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 642, 1073377 Aeromonas hydrophila SSU Bacteria UP000005149 491450391, 404629312 EKB26073.1 WP_005308177.1 fig|1073377.4.peg.3991 645 663 yes 1891622 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 897, 1121405 Desulfococcus multivorans, Desulfococcus multivorans DSM 2059 Bacteria UP000014977 527025581, 523467841 EPR39706.1 WP_020877311.1 420 439 yes 1891623 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1773, 668349 Mycobacterium tuberculosis, Mycobacterium tuberculosis T67 Bacteria UP000065426, UP000026394 686017230, 623379357 KBJ48219.1 WP_031715172.1 544 547 yes 1891624 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 148813, 709032 Sulfuricurvum kujiense, Sulfuricurvum kujiense DSM 16994 Bacteria UP000008721 503224858, 313154644 ADR33322.1 WP_013459519.1 fig|709032.3.peg.918 457 458 yes 1891625 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1194398 Pseudomonas syringae pv. actinidiae ICMP 19079 Bacteria UP000015888 519292855 EPN59740.1 445 457 yes 1891626 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 480 480 yes 1891627 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144317 Acidovorax sp. CF316 Bacteria UP000004811 495132587, 394313934 EJE50896.1 WP_007857398.1 fig|1144317.3.peg.4199 623 631 yes 1891628 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 514843364 WP_016588558.1 209 228 no 1891629 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 274, 262724 Thermus thermophilus, Thermus thermophilus HB27 Bacteria UP000000592 499486130, 46196250, 81567752 AAS80667.1 WP_011172770.1 Q72KP6 THIC_THET2 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 499189 fig|262724.1.peg.319 433 435 yes 1891630 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 421 432 yes 1891631 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65555, 1167006 Desulfocapsa sulfexigens, Desulfocapsa sulfexigens DSM 10523 Bacteria UP000011721 505215995, 451905807 AGF77401.1 WP_015403097.1 fig|1167006.5.peg.930 620 620 yes 1891632 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3847 Glycine max Plants UP000008827 UP000008827 571489428, 356539595 XP_006591209.1, XP_003538282.1 541 648 yes 1891633 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 612 613 yes 1891634 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1217984 Bacillus cereus, Bacillus cereus FRI-35 Bacteria UP000036076, UP000011845 446737217, 401795898 AFQ09757.1 WP_000814473.1 fig|1217984.3.peg.1868 586 586 yes 1891635 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 629261 Pseudomonas syringae pv. mori str. 301020 Bacteria UP000003465 330886487 EGH20228.1 627 629 yes 1891636 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 696485, 1229493 Vibrio owensii, VIbrio owensii CAIM 1854 = LMG 25443 Bacteria UP000031586 519041074, 747028917 KIF48764.1 WP_020196949.1 640 646 yes 1891637 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 436 438 yes 1891638 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 104102, 749388 Acetobacter tropicalis, Acetobacter tropicalis NBRC 101654 Bacteria UP000029448, UP000004319 493606350, 338751445 WP_006558890.1 607 673 yes 1891639 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1446467, 1227739 Hymenobacter swuensis, Hymenobacter sp. DY53 Bacteria UP000019423 763123696, 586957826 AHJ99560.1 WP_044003607.1 625 625 yes 1891640 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570, 573, 1328376 Klebsiella pneumoniae, Klebsiella pneumoniae MGH 44 Bacteria UP000036212, UP000017406 556467703, 839765115, 839713502, 555119016 KMI38041.1, KMH86967.1, ESM61942.1 WP_023319462.1 626 631 yes 1891641 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 755731 Clostridium sp. BNL1100 Bacteria UP000007324 504079892, 373945599 AEY66520.1 WP_014313886.1 fig|755731.4.peg.2337 436 436 yes 1891642 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262754 Bacteroides sp. CAG:98 Environmental samples UP000018115 548316596, 524820861 WP_022506468.1 567 567 yes 1891643 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76759 Pseudomonas monteilii Bacteria UP000065993 515082663 WP_016712346.1 625 626 yes 1891644 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1427517 Xenorhabdus cabanillasii JM26 Bacteria UP000019197 575853353 625 661 yes 1891645 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262879 Eubacterium sp. CAG:146 Environmental samples UP000018404 546971475, 524032988 WP_021907192.1 434 434 yes 1891646 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 1400187 Serratia marcescens, Serratia marcescens BIDMC 50 Bacteria UP000055021, UP000020900 727181902, 575543695 ETX44117.1 WP_033644366.1 632 647 yes 1891647 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935543 Burkholderia sp. WSM4176 Bacteria 517232299 WP_018421117.1 642 643 yes 1891648 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 948, 1392505 Anaplasma phagocytophilum, Anaplasma phagocytophilum str. MRK Bacteria UP000033356, UP000053426 763291631, 633296460 KDB55937.1 WP_044152451.1 557 557 yes 1891649 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 1339275 Bacteroides fragilis, Bacteroides fragilis str. Ds-233 Bacteria UP000036847, UP000022285 695574121, 596036116 EXZ13773.1 WP_032601047.1 564 564 yes 1891650 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1294263 Clostridium straminisolvens JCM 21531 Bacteria UP000019109 575090636 148 149 no 1891651 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 869685, 1281248, 1280988, 1182693, 1169366, 1169399, 1169390, 1169386, 1169377, 1181761, 1181753, 1181729, 1181740, 1169360, 1182736, 1182696, 1182691, 1182679, 1181770, 1169335, 1169334, 753642 Escherichia coli, Escherichia coli 9.1649, Escherichia coli UMEA 3391-1, Escherichia coli HVH 38 (4-2774682), Escherichia coli KTE89, Escherichia coli KTE88, Escherichia coli KTE168, Escherichia coli KTE145, Escherichia coli KTE133, Escherichia coli KTE113, Escherichia coli KTE215, Escherichia coli KTE207, Escherichia coli KTE183, Escherichia coli KTE194, Escherichia coli KTE43, Escherichia coli KTE169, Escherichia coli KTE93, Escherichia coli KTE86, Escherichia coli KTE72, Escherichia coli KTE224, Escherichia coli KTE16, Escherichia coli KTE15, Escherichia coli NC101 Bacteria UP000036210, UP000032820, UP000016153, UP000016043, UP000014198, UP000010625, UP000010657, UP000010526, UP000010512, UP000010602, UP000010508, UP000010589, UP000010525, UP000010639, UP000010713, UP000010530, UP000010578, UP000010515, UP000010671, UP000010627, UP000010511, UP000010540, UP000005190 446039458, 822071684, 802475591, 746673844, 535780342, 534685895, 508415776, 431700907, 431656546, 431614722, 431597012, 431547451, 431492854, 431489603, 431459253, 431425831, 431288977, 431239293, 431187070, 431177237, 431145731, 431037489, 430911647, 430902712, 305854614 KLD43848.1, KKA62855.1, KIE65181.1, EQZ13602.1, EQO41721.1, EOV86264.1, ELJ65833.1, ELJ23527.1, ELI83859.1, ELI66937.1, ELI21830.1, ELH72452.1, ELH69229.1, ELH39567.1, ELH07878.1, ELF79730.1, ELF33934.1, ELE86590.1, ELE77171.1, ELE47341.1, ELD48471.1, ELC32922.1, ELC24559.1, EFM55050.1 WP_000117313.1 fig|1181761.3.peg.4480, fig|1169334.3.peg.4211, fig|869685.3.peg.285, fig|753642.3.peg.20, fig|1181740.3.peg.4799, fig|1182679.3.peg.4529, fig|1169386.3.peg.4192, fig|1169390.3.peg.4290, fig|1308983.3.peg.4636, fig|1182696.3.peg.4536, fig|1182736.3.peg.4449, fig|1169377.3.peg.4525, fig|1169360.3.peg.4243, fig|1181729.3.peg.3313, fig|1181770.3.peg.4416, fig|1182693.3.peg.4213, fig|1182691.3.peg.4610, fig|1181753.3.peg.142, fig|1169399.3.peg.4311, fig|1169335.3.peg.144, fig|1169366.3.peg.3990 626 631 yes 1891652 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1294263 Clostridium straminisolvens JCM 21531 Bacteria UP000019109 575090635 288 292 no 1891653 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354276, 1329813, 1329822 Enterobacter sp. MGH 4, Enterobacter sp. MGH 13 Bacteria UP000020388, UP000021912 695668668, 578330886, 578298253 EUM90093.1, EUM57891.1 WP_032626494.1 626 631 yes 1891654 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 629 647 yes 1891655 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 936351 Bifidobacterium breve, Bifidobacterium breve S27 Bacteria UP000029049, UP000019333 644612681, 585136656 AHJ25124.1 WP_025341833.1 635 917 yes 1891656 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1556, 1128398 Clostridium acidurici, Clostridium acidurici 9a Bacteria UP000006094 504779662, 407049582 AFS77627.1 WP_014966764.1 fig|1128398.3.peg.580 435 435 yes 1891657 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 292566, 13035 Dactylococcopsis salina, Dactylococcopsis salina PCC 8305 Bacteria UP000010482 505043081, 428695043 AFZ51193.1 WP_015230183.1 fig|13035.3.peg.2970 456 458 yes 1891658 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 552, 1027397, 1219359, 1407064, 1407063, 1407062, 1255308, 1255307, 1255306, 1255305, 1255304, 1255303, 665029, 716540 Erwinia amylovora, Erwinia amylovora ACW56400, Erwinia amylovora NBRC 12687, Erwinia amylovora LA637, Erwinia amylovora LA636, Erwinia amylovora LA635, Erwinia amylovora UPN527, Erwinia amylovora CFBP 1232, Erwinia amylovora 01SFR-BO, Erwinia amylovora CFBP 2585, Erwinia amylovora Ea266, Erwinia amylovora Ea356, Erwinia amylovora CFBP1430, Erwinia amylovora ATCC 49946 Bacteria UP000010182, UP000026940, UP000018602, UP000018506, UP000018508, UP000013252, UP000013111, UP000013146, UP000013272, UP000013217, UP000013229, UP000001841, UP000008873 490257778, 426277844, 635552942, 566690864, 565457548, 565426638, 478722076, 478718299, 478714521, 478710655, 478706913, 478703110, 291552157, 291197820 EKV55568.1 WP_004155007.1 fig|1255306.3.peg.256, fig|1255308.3.peg.255, fig|1255305.3.peg.255, fig|1255307.3.peg.255, fig|716540.3.peg.246, fig|1255304.3.peg.266, fig|1255303.3.peg.259, fig|665029.3.peg.277 631 644 yes 1891659 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1254439 Bifidobacterium thermophilum RBL67 Bacteria UP000011835 469498299 AGH40825.1 fig|1254439.12.peg.560 594 960 yes 1891660 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1248760 Blastomonas sp. AAP53 Bacteria 516265726 WP_017669689.1 628 634 yes 1891661 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 428031 Moritella sp. ArB0140 Bacteria 515790097 WP_017222506.1 653 689 yes 1891662 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354276, 550, 1329812, 1329823, 1432556 Enterobacter cloacae, Enterobacter sp. MGH 3, Enterobacter sp. MGH 14, Enterobacter cloacae ISC8 Bacteria UP000036177, UP000021243, UP000017108, UP000019204 550794715, 838695033, 829316551, 829310299, 794263891, 771171763, 771087370, 763839648, 742989464, 578344540, 550215250, 808680463, 571251350 KLW78581.1, KLQ09362.1, KLQ03224.1, KJX21263.1, KJN24601.1, KJM61720.1, KJB99552.1, AJB80065.1, EUN03599.1, ERP05603.1 WP_022650206.1 626 631 yes 1891663 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 593750 Methanoregula formicicum SMSP Archaea UP000010824 432136288 AGB01215.1 L0HB45 L0HB45_METFS 413 438 no 1891664 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 544, 546, 1297584, 1212820, 1173691 Citrobacter freundii, Citrobacter freundii GTC 09629, Citrobacter sp. L17, Citrobacter sp. A1 Bacteria UP000030582, UP000013524, UP000009391, UP000006187 489123273, 838554267, 486074534, 422892334, 394715713 KLV38878.1, EOD58484.1, EKU32196.1, EJF21505.1 WP_003033079.1 fig|1173691.3.peg.3547, fig|1297584.3.peg.3781, fig|1212820.3.peg.4534 626 632 yes 1891665 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1078086 Streptomyces sp. HGB0020 Bacteria UP000014410 512503259, 512057159 EPD56659.1 WP_016436999.1 fig|1078086.3.peg.7186 592 594 yes 1891666 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1443113 Yersinia enterocolitica LC20 Bacteria UP000019587 595643932 AHM76187.1 640 664 yes 1891667 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386078 Pseudomonas sp. EGD-AK9 Bacteria UP000016488 542138858 ERI54229.1 586 586 yes 1891668 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423 Bacillus subtilis Bacteria UP000030083 518542291 WP_019712498.1 590 590 yes 1891669 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1435047 Acinetobacter baumannii MDR_MMC4 Bacteria UP000019154 575766183 ETY67893.1 621 625 yes 1891670 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217710 Acinetobacter sp. NIPH 899 Bacteria UP000013070 490925380, 479951842 ENU97502.1 WP_004787245.1 fig|1217710.3.peg.3587 626 631 yes 1891671 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 930 Acidithiobacillus thiooxidans Bacteria 498325030 WP_010639186.1 627 628 yes 1891672 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 290053, 693979 Bacteroides helcogenes, Bacteroides helcogenes P 36-108 Bacteria UP000008630 503313260, 319417220 ADV44331.1 WP_013547921.1 fig|693979.3.peg.2477 568 570 yes 1891673 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 114 Gemmata obscuriglobus Bacteria 497732713 WP_010046897.1 441 442 yes 1891674 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 546, 1333848 Citrobacter freundii, Citrobacter freundii CFNIH1 Bacteria UP000030582, UP000025226 740850884, 619736133 AHY11372.1 WP_038636137.1 626 632 yes 1891675 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 530 530 yes 1891676 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 516396603 WP_017786001.1 667 685 yes 1891677 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1047068 519094469 WP_020250344.1 422 422 yes 1891678 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 213585, 1434117, 192952 Methanosarcina mazei S-6, Methanosarcina mazei WWM610, Methanosarcina mazei Go1 Archaea UP000033097, UP000033058, UP000000595 805367201, 805360299, 20904528 AKB64313.1, AKB40088.1, AAM29878.1 Q8Q0F4, A0A0E3PWG3, A0A0E3RIJ4 THIC1_METMA Phosphomethylpyrimidine synthase 1 {ECO:0000255|HAMAP-Rule:MF_00089} A0A0E3PWG3_METMZ, A0A0E3RIJ4_METMZ 248147 fig|192952.1.peg.182 462 473 yes 1891679 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1428, 529122 Bacillus thuringiensis, Bacillus thuringiensis YBT-1518 Bacteria UP000031834, UP000018566 558694093, 558582846 AHA74981.1 WP_023523510.1 586 586 yes 1891680 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 251701, 629265 Pseudomonas syringae group genomosp. 3, Pseudomonas syringae pv. maculicola str. ES4326 Bacteria UP000003811 494461468, 330960118 EGH60378.1 WP_007251035.1 627 629 yes 1891681 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28090, 981327 Acinetobacter lwoffii, Acinetobacter lwoffii NCTC 5866 Bacteria UP000018447 491236198, 480087544 ENW25974.1 WP_005094421.1 627 631 yes 1891682 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 562 Escherichia coli Bacteria UP000036210 519085383 WP_020241258.1 329 332 no 1891683 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 88036 Selaginella moellendorffii Plants UP000001514 302805847, 300147656 EFJ14319.1 XP_002984674.1 551 623 yes 1891684 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294, 1221522 Pseudomonas fluorescens, Pseudomonas fluorescens NCIMB 11764 Bacteria UP000060991, UP000017175 515905642, 550268206 ERP39739.1 WP_017336225.1 627 629 yes 1891685 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262805 Clostridium sp. CAG:43 Environmental samples UP000018284 547958504, 524644062 WP_022358877.1 63 64 no 1891686 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294, 1038922 Pseudomonas fluorescens, Pseudomonas fluorescens Q2-87 Bacteria UP000060991, UP000007289 489278820, 397887616 EJL04099.1 WP_003186482.1 fig|1038922.3.peg.347 628 629 yes 1891687 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34073, 595537 Variovorax paradoxus, Variovorax paradoxus EPS Bacteria UP000050323, UP000008917 503309062, 315598455 ADU39521.1 WP_013543723.1 fig|595537.3.peg.5430 624 628 yes 1891688 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 876 Desulfovibrio desulfuricans Bacteria 550906339 WP_022659507.1 419 426 no 1891689 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1412569 Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120994 Bacteria UP000023604 603577925 AHS50204.1 449 452 no 1891690 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 319003 Bradyrhizobium sp. WSM1253 Bacteria UP000005125 494874669, 385741360 EIG61556.1 WP_007600764.1 623 632 yes 1891691 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1392500, 1400183, 1328392, 1244085, 1267897, 1379688 Klebsiella pneumoniae, Klebsiella pneumoniae HK787, Klebsiella pneumoniae UCI 42, Klebsiella pneumoniae UCICRE 6, Klebsiella pneumoniae CG43, Klebsiella pneumoniae hvKP1, Klebsiella pneumoniae SA1 Bacteria UP000036212, UP000031117, UP000023036, UP000017290, UP000017137, UP000011501, UP000019201 490323372, 742684563, 583441605, 555052996, 549819688, 448875242, 573081790 AJB34762.1, EWD05800.1, ESL97241.1, AGX40305.1, EMB10265.1 WP_004212857.1 fig|1267897.3.peg.2842 626 631 yes 1891692 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1042876 Pseudomonas putida S16 Bacteria UP000000502 338840491 AEJ15296.1 fig|1042876.5.peg.4846, fig|1215088.3.peg.4824 626 627 yes 1891693 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1104682 Pseudomonas syringae pv. actinidiae ICMP 18804 Bacteria UP000015681 519226023 EPN07518.1 193 204 no 1891694 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 186192, 869210 Marinithermus hydrothermalis, Marinithermus hydrothermalis DSM 14884 Bacteria UP000007030 503469865, 328451579 AEB12480.1 WP_013704526.1 fig|869210.3.peg.1733 439 440 yes 1891695 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 876, 641491 Desulfovibrio desulfuricans, Desulfovibrio sp. ND132 Bacteria UP000007845 504087512, 323458213 EGB14078.1 WP_014321506.1 434 434 yes 1891696 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 301375, 1110509 Methanosaeta harundinacea, Methanosaeta harundinacea 6Ac Archaea UP000053961, UP000005877 504399025, 357209322 AET63942.1 WP_014586127.1 G7WN86 G7WN86_METH6 411 421 no 1891697 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1145159 Neisseria meningitidis, Neisseria meningitidis 81858 Bacteria UP000050419, UP000013309 488185787, 485350667 EOC12154.1 WP_002256995.1 fig|1145159.3.peg.2685 625 633 yes 1891698 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4113 Solanum tuberosum Plants UP000011115 565354279, 565354276 XP_006344043.1, XP_006344042.1 545 651 yes 1891699 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1030157 Sphingomonas sp. KC8 Bacteria 497812051 WP_010126235.1 615 619 yes 1891700 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1336203 Pseudomonas aeruginosa, Pseudomonas aeruginosa MH38 Bacteria UP000065817, UP000024473 727812472, 815974506, 751377279, 571151186 AKE72665.1, AJF53107.1 WP_033896094.1 627 627 yes 1891701 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286420 Hahella ganghwensis Bacteria 521079431 WP_020410338.1 619 620 yes 1891702 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29291, 259564 Methanococcoides burtonii, Methanococcoides burtonii DSM 6242 Archaea UP000001979 499818811, 91712474 ABE52401.1 WP_011499545.1 Q12VX5 Q12VX5_METBU fig|259564.8.peg.1423 420 427 yes 1891703 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 70775, 1586081, 303, 1435058, 1435044, 1388762, 1215088 Pseudomonas plecoglossicida, Pseudomonas sp. C5pp, Pseudomonas putida, Pseudomonas monteilii SB3101, Pseudomonas monteilii SB3078, Pseudomonas taiwanensis SJ9, Pseudomonas putida HB3267 Bacteria UP000031767, UP000031298, UP000054813, UP000018660, UP000018760, UP000018511, UP000010800 505084923, 752314507, 742791661, 694935329, 635296911, 567360190, 567352610, 562740593, 430795509 AJG17116.1, KIC84083.1, KGK27774.1, AHZ79653.1, AHC90178.1, AHC84807.1, ESW37812.1, AGA75704.1 WP_015272025.1 fig|1042876.5.peg.4846, fig|1215088.3.peg.4824 625 626 yes 1891704 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 913080 Salmonella enterica, Salmonella enterica subsp. enterica serovar Mississippi str. A4-633 Bacteria UP000054489, UP000003218 446619192, 353612687 EHC65000.1 WP_000696538.1 fig|913080.3.peg.4406 292 294 yes 1891705 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2711, 85681 Citrus sinensis, Citrus clementina Plants UP000027120, UP000030687 568870597, 567864768, 567864766, 567864764, 567864762, 557526967, 557526966, 557526965, 557526964 ESR38273.1, ESR38272.1, ESR38271.1, ESR38270.1 XP_006488486.1, XP_006425033.1, XP_006425032.1, XP_006425031.1, XP_006425030.1 553 646 yes 1891706 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262759 Brachyspira sp. CAG:484 Environmental samples UP000018274 547150465, 524857082 WP_021918417.1 424 424 yes 1891707 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1038866 Bradyrhizobium japonicum WSM2793 Bacteria 517129801 WP_018318619.1 623 632 yes 1891708 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 556 557 yes 1891709 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28123, 879243 Porphyromonas asaccharolytica, Porphyromonas asaccharolytica DSM 20707 Bacteria UP000006545 503526226, 332177252 AEE12942.1 WP_013760415.1 fig|879243.3.peg.970 590 590 yes 1891710 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 388640, 1094489 Bartonella australis, Bartonella australis Aust/NH1 Bacteria UP000011729 505210696, 451899827 AGF74290.1 WP_015397798.1 fig|1094489.3.peg.505 602 611 yes 1891711 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354276, 550, 1328422, 1410032, 1439324, 1329816, 1329836, 1329846, 1400150, 1400151, 1329844 Enterobacter cloacae, Klebsiella pneumoniae BIDMC 33A, Enterobacter cloacae MRSN 11489, Enterobacter cloacae BIDMC 66, Enterobacter sp. MGH 7, Enterobacter sp. BWH 37, Enterobacter cloacae BIDMC 8, Enterobacter cloacae UCI 35, Enterobacter cloacae UCI 36, Enterobacter cloacae BWH 29 Bacteria UP000036177, UP000032525, UP000031481, UP000027016, UP000020881, UP000020549, UP000020302, UP000020928, UP000020055, UP000017417 556463415, 838692864, 838668612, 838636825, 838635635, 838624401, 838621274, 829607670, 829602958, 822844807, 822573131, 794285801, 794261514, 794258126, 772516620, 772507011, 772496395, 772495848, 772491866, 772487720, 772475599, 772464090, 772462265, 771446056, 771435051, 771431266, 771415603, 771414267, 771398507, 771398306, 771386768, 771384271, 771362520, 771360692, 771346733, 771345885, 771344575, 771335333, 771333802, 771289737, 771276257, 771263224, 771247499, 771235033, 771062714, 771043923, 771030751, 771029726, 771008702, 770968706, 768665242, 768665207, 768661028, 768652278, 768649855, 768642318, 768638787, 768634180, 768618407, 768613452, 768605868, 768603603, 768598226, 768593898, 768587560, 768579458, 768566367, 768554589, 768554342, 766653701, 738553444, 736289064, 736254253, 733833977, 733829955, 733822424, 733820059, 733815656, 733806100, 733804495, 733803537, 733557040, 733556074, 733543250, 733542996, 733532974, 733520083, 733519190, 733519096, 728954958, 723106196, 635755673, 578325276, 578281084, 578266875, 578209505, 578205790, 555103431 KLW76432.1, KLW52358.1, KLW20832.1, KLW19655.1, KLW08528.1, KLW05416.1, KLR68584.1, KLR64004.1, KLG02800.1, KLE18925.1, KJX42345.1, KJX18926.1, KJX15688.1, KJQ44155.1, KJQ34702.1, KJQ24276.1, KJQ23759.1, KJQ19875.1, KJQ15827.1, KJQ04142.1, KJP92806.1, KJP91044.1, KJP76640.1, KJP65934.1, KJP62264.1, KJP46956.1, KJP45683.1, KJP30350.1, KJP30161.1, KJP18968.1, KJP16559.1, KJO95353.1, KJO93629.1, KJO80038.1, KJO79224.1, KJO78024.1, KJO69077.1, KJO67615.1, KJO25000.1, KJO11949.1, KJN99203.1, KJN84116.1, KJN71934.1, KJM42480.1, KJM28943.1, KJM16149.1, KJM15925.1, KJL93172.1, KJL63930.1, KJI97305.1, KJI97271.1, KJI93225.1, KJI84629.1, KJI82296.1, KJI74949.1, KJI71481.1, KJI67033.1, KJI51504.1, KJI46631.1, KJI39204.1, KJI36962.1, KJI31715.1, KJI27475.1, KJI21263.1, KJI13328.1, KJI00654.1, KJH89221.1, KJH88988.1, KJF29421.1, KHQ56948.1, KHQ45127.1, KHQ15213.1, KHM86157.1, KHM82226.1, KHM74809.1, KHM72520.1, KHM68208.1, KHM58795.1, KHM57224.1, KHM56311.1, KHM37419.1, KHM36473.1, KHM23833.1, KHM23588.1, KHM13837.1, KHM01154.1, KHM00315.1, KHM00230.1, KHG44234.1, KHC24335.1, KDF37247.1, EUM84582.1, EUM40912.1, EUM26830.1, EUL69719.1, EUL66019.1, ESM46505.1 WP_023315206.1 626 631 yes 1891712 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 693444 Enterobacteriaceae bacterium strain FGI 57 Bacteria UP000011002 440049100 AGB80158.1 626 659 yes 1891713 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59931 Synechococcus sp. WH 7805 Bacteria UP000001224 492912114, 88788240 EAR19396.1 WP_006042520.1 fig|59931.3.peg.1693 465 467 yes 1891714 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 397290 Lachnospiraceae bacterium A2 Bacteria UP000014150 511050156, 507789827 EOS47686.1 WP_016303988.1 433 434 yes 1891715 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 672, 914127 Vibrio vulnificus, Vibrio vulnificus MO6-24/O Bacteria UP000054370, UP000006905 503337958, 319933100 ADV87964.1 WP_013572619.1 fig|914127.3.peg.2921 639 647 yes 1891716 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1163065 Pseudomonas sp. CBZ-4 Bacteria 516344900 WP_017734933.1 628 629 yes 1891717 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 103855, 1331257 Bordetella hinzii, Bordetella hinzii 5132 Bacteria UP000036132, UP000026398 759503258, 625325217 KCB39779.1 WP_043224035.1 636 637 yes 1891718 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 43080, 930943 Sulfolobus islandicus, Sulfolobus islandicus HVE10/4 Archaea UP000006395 504325043, 385772594, 323476708 ADX81946.1 WP_014512145.1, YP_005645160.1 F0NNI8 F0NNI8_SULIH 164 211 no 1891719 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 136996, 1229491 Rhizobium lupini, Rhizobium lupini HPC(L) Bacteria UP000017668 493750148, 408486678 EKJ95003.1 WP_006699107.1 fig|1229491.3.peg.3160 599 607 yes 1891720 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 215, 1325130 Helicobacter fennelliae, Helicobacter fennelliae MRY12-0050 Bacteria UP000018143 565866008, 522683763 WP_023947806.1 452 453 yes 1891721 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305700 Thauera sp. 27 Bacteria UP000013140 489032495, 479289098 ENO77198.1 WP_002942875.1 638 638 yes 1891722 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169160 Streptomyces sp. CNS335 Bacteria 517670903 WP_018841111.1 598 602 yes 1891723 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1145127 Neisseria meningitidis 69100 Bacteria UP000013340 485286202 EOB52034.1 fig|1145127.3.peg.2704 512 545 no 1891724 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1416614, 1183438 Gloeobacter kilaueensis, Gloeobacter kilaueensis JS1 Bacteria UP000017396 554670595, 553882045 AGY57487.1 WP_023172577.1 455 459 yes 1891725 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573065 Asticcacaulis excentricus CB 48 Bacteria UP000001492 315416047 ADU12688.1 fig|573065.5.peg.293 613 617 yes 1891726 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44012, 550540 Ferrimonas balearica, Ferrimonas balearica DSM 9799 Bacteria UP000006683 503110803, 307631935 ADN76237.1 WP_013345543.1 fig|550540.3.peg.2056 635 646 yes 1891727 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 329, 1264675 Ralstonia pickettii, Ralstonia pickettii OR214 Bacteria UP000029114, UP000013280 490766155, 480895606 ENZ78722.1 WP_004628389.1 fig|1264675.3.peg.1249 633 635 yes 1891728 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56459, 1094180, 1094181, 1094174, 1184265, 1184266 Xanthomonas vasicola, Xanthomonas vasicola pv. vasculorum NCPPB 1381, Xanthomonas vasicola pv. vasculorum NCPPB 206, Xanthomonas vasicola pv. vasculorum NCPPB 1326, Xanthomonas vasicola pv. vasculorum NCPPB 890, Xanthomonas vasicola pv. vasculorum NCPPB 895 Bacteria UP000030936, UP000028162, UP000028171, UP000028165, UP000028167, UP000028161 498050243, 712765365, 704131561, 704122480, 704118004, 667161758, 667159261, 667149170, 667106095, 667097497 KGT83648.1, KGR63835.1, KGR56254.1, KGR52183.1, KFA36188.1, KFA33815.1, KFA24349.1, KFA03102.1, KEZ96828.1 WP_010364399.1 624 625 yes 1891729 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 523829, 702985 Salmonella enterica, Salmonella enterica subsp. enterica serovar Paratyphi B str. ATCC BAA-1585, Salmonella enterica subsp. enterica serovar Paratyphi B str. SARA62 Bacteria UP000054489, UP000017461, UP000017365 554681727, 554160054, 554029997 ESF99786.1, ESE76185.1 WP_023181683.1 626 631 yes 1891730 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 550, 1659711, 1329831, 1329839, 1329855, 718254 Enterobacter cloacae, Enterobacter sp. GN02457, Enterobacter sp. MGH 33, Enterobacter sp. BIDMC 27, Enterobacter cloacae UCICRE 11, Enterobacter cloacae subsp. cloacae NCTC 9394 Bacteria UP000036177, UP000037649, UP000021217, UP000020210, UP000017302, UP000008800 505382866, 838705663, 838693387, 838682562, 838661909, 829399588, 829367236, 829355729, 829280151, 822842132, 771374450, 771325874, 736283692, 733532382, 578295312, 578263460, 555036590, 295095118 KLW89111.1, KLW76947.1, KLW66210.1, KLW45696.1, KLQ91020.1, KLQ59274.1, KLQ47975.1, KLP76693.1, KLG00197.1, KJP07111.1, KJO60010.1, KHQ39800.1, KHM13301.1, EUM55014.1, EUM23482.1, ESL80914.1 WP_015569968.1 626 631 yes 1891731 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263869, 1263870 Rhodopirellula sallentina, Rhodopirellula sallentina SM41 Bacteria UP000011885 495949499, 460934834 EMI57999.1 WP_008674078.1 fig|1263870.3.peg.568 439 441 yes 1891732 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44255, 1245469 Agromonas oligotrophica, Agromonas oligotrophica S58 Bacteria UP000011841 505478479, 456353464 WP_015665036.1 fig|1245469.3.peg.1940 622 633 yes 1891733 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 1385939, 326426 Bifidobacterium breve, Bifidobacterium breve JCM 7017, Bifidobacterium breve UCC2003 Bacteria UP000029049, UP000019329, UP000000297 505251904, 585128983, 339479519 AHJ17773.1, ABE95987.1 WP_015439006.1 fig|326426.4.peg.1408 636 917 yes 1891734 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1379698 candidate division ZIXI bacterium RBG-1 Bacteria UP000015604 530551937 EQB63356.1 463 464 yes 1891735 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 437163 Halomicrobium katesii Archaea 517069807 WP_018258625.1 465 476 yes 1891736 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 231023 Pseudomonas sp. ND6 Bacteria UP000005268 388559762 AFK68903.1 fig|1196325.3.peg.1194, fig|1193146.3.peg.3495, fig|1081940.5.peg.4954, fig|1193499.3.peg.2265, fig|1227924.3.peg.5267, fig|231023.4.peg.1897, fig|351746.4.peg.4741 626 627 yes 1891737 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1234594 Pseudomonas sp. 313 Bacteria 516236796 WP_017640759.1 625 625 yes 1891738 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281269 Escherichia coli, Escherichia coli UMEA 3718-1 Bacteria UP000036210, UP000016336 545297978, 535863254 EQZ95023.1 WP_021578183.1 626 631 yes 1891739 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 183417, 1312367 Proteus hauseri, Proteus hauseri ZMd44 Bacteria UP000018077 559235756, 558647039 EST57519.1 WP_023583101.1 620 650 yes 1891740 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 935705, 149539, 1064551 Salmonella enterica, Salmonella enterica subsp. enterica serovar Thompson str. ATCC 8391, Salmonella enterica subsp. enterica serovar Enteritidis, Salmonella enterica subsp. enterica serovar Thompson str. RM6836 Bacteria UP000054489, UP000017632, UP000034332, UP000018500 516035551, 820766828, 808226514, 548716909 AKG83697.1, KKD72644.1, AGX12549.1 WP_017466134.1 626 631 yes 1891741 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 563, 630626 Escherichia blattae, Escherichia blattae DSM 4481 Bacteria UP000014042 488375875, 386925806, 403193226 AFJ48760.1 WP_002445260.1 fig|630626.3.peg.3628, fig|1115514.3.peg.3676 626 633 yes 1891742 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 497965 Cyanothece sp. PCC 7822 Bacteria UP000008206 503088584, 306983482 ADN15363.1 WP_013323432.1 fig|497965.5.peg.1571 454 456 yes 1891743 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1087449 Aquimarina agarilytica Bacteria 497863677 WP_010177833.1 620 620 yes 1891744 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262735 Bacteroides sp. CAG:1076 Environmental samples UP000018060 547233566, 524114684 WP_021970056.1 564 564 yes 1891745 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 317, 629264 Pseudomonas syringae, Pseudomonas syringae Cit 7 Bacteria UP000028642, UP000005924 489447315, 330955724 EGH55984.1 WP_003352720.1 157 157 no 1891746 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66269, 660596 Pantoea stewartii, Pantoea stewartii subsp. stewartii DC283 Bacteria UP000030462, UP000005050 493072184, 377815506 EHT98620.1 WP_006121505.1 fig|660596.6.peg.4302 632 640 yes 1891747 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 627 646 yes 1891748 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630, 1262465 Yersinia enterocolitica, Yersinia enterocolitica (type O:5,27) str. YE149/02 Bacteria UP000029427, UP000018099 554498689, 545725545 WP_023160435.1 617 628 yes 1891749 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1721, 1121353 Corynebacterium callunae, Corynebacterium callunae DSM 20147 Bacteria UP000011760 505464193, 459384361 AGG66652.1 WP_015651084.1 fig|1121353.3.peg.1235 596 598 yes 1891750 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1299330 Mycobacterium avium 2285 (R) Bacteria UP000029489 576445125 EUA38766.1 378 379 yes 1891751 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 546267 Neisseria polysaccharea ATCC 43768 Bacteria UP000003508 296838378 EFH22316.1 625 655 yes 1891752 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 1385940 Bifidobacterium breve, Bifidobacterium breve JCM 7019 Bacteria UP000029049, UP000019336 643504401, 585131212 AHJ19683.1 WP_025221914.1 642 917 yes 1891753 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1457154 Candidatus Accumulibacter sp. SK-01 Bacteria UP000019812 736923962, 668674726 KFB69957.1 WP_034921363.1 638 638 yes 1891754 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 541 542 yes 1891755 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262875 Eggerthella sp. CAG:209 Environmental samples UP000018042 547773111, 524382665 WP_022184501.1 440 442 yes 1891756 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 555500 Gillisia sp. ck-I2-15 Bacteria UP000007364 496280773, 407742344 EKF53947.1 WP_008992811.1 fig|555500.3.peg.3072 618 618 yes 1891757 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2277, 384616 Pyrobaculum islandicum, Pyrobaculum islandicum DSM 4184 Archaea UP000002595 500087168, 119872942, 119674350 ABL88606.1 WP_011763181.1, YP_930949.1 A1RUH4 A1RUH4_PYRIL 2045694 fig|384616.5.peg.1422 421 430 no 1891758 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2214 Methanosarcina acetivorans Archaea 499329827 WP_011020319.1 fig|188937.1.peg.260 406 415 no 1891759 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314280 Photobacterium profundum 3TCK Bacteria UP000003789 90326352 EAS42771.1 fig|314280.3.peg.4451 638 647 yes 1891760 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 565040 Bifidobacterium longum, Bifidobacterium longum subsp. infantis 157F Bacteria UP000028505, UP000008150 505911446, 716055515, 320460896 WP_015713748.1 fig|565040.3.peg.1411 635 917 yes 1891761 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1736, 903814 Eubacterium limosum, Eubacterium limosum KIST612 Bacteria UP000061973, UP000006873 503147802, 308741497 ADO39157.1 WP_013382463.1 fig|903814.3.peg.3908 421 427 yes 1891762 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1736, 903814 Eubacterium limosum, Eubacterium limosum KIST612 Bacteria UP000061973, UP000006873 503147803, 308741498 ADO39158.1 WP_013382464.1 fig|903814.3.peg.3909 421 427 yes 1891763 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423, 1052585 Bacillus subtilis, Bacillus subtilis subsp. spizizenii TU-B-10 Bacteria UP000030083, UP000002651 503879132, 349598036 AEP85824.1 WP_014113126.1 fig|1052585.4.peg.1068 590 590 yes 1891764 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1432552, 1411646 Klebsiella pneumoniae IS43, Klebsiella pneumoniae IS10 Bacteria UP000019183, UP000036621 571229587, 571203690 468 470 yes 1891765 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 657314 Ruminococcus obeum A2-162 Bacteria UP000008955 295109180 436 436 yes 1891766 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294, 743713 Pseudomonas fluorescens, Pseudomonas fluorescens R124 Bacteria UP000060991, UP000006045 489313667, 404302245 EJZ56207.1 WP_003221055.1 628 629 yes 1891767 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1329828 Enterobacter sp. MGH 24 Bacteria UP000017624 556486257, 555172473 ESN15513.1 WP_023334106.1 626 631 yes 1891768 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 72407, 1328382 Klebsiella pneumoniae, Klebsiella pneumoniae subsp. pneumoniae, Klebsiella pneumoniae BWH 15 Bacteria UP000036212, UP000060052, UP000020205 694076308, 723234606, 583675292 AIX67245.1, EWF37657.1 WP_032422050.1 626 631 yes 1891769 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 890402 Bifidobacterium longum, Bifidobacterium longum subsp. longum BBMN68 Bacteria UP000028505, UP000006891 503175896, 311773008 ADQ02496.1 WP_013410557.1 fig|890402.3.peg.169 635 917 yes 1891770 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1094563 Bartonella washoensis Sb944nv Bacteria UP000008947 395415141 EJF81576.1 fig|1094563.3.peg.296 574 583 yes 1891771 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1299325, 1299322, 1299324, 1335409, 1335410, 1335416, 1335417, 1001717, 1001724, 1001725, 1001719, 1001720, 1001718, 1001716, 1001715, 1001721, 1001723, 1001737, 1001739, 1001736, 1001738, 1001740, 1001741, 1001726, 1001727, 1001722 Mycobacterium abscessus 103, Mycobacterium chelonae 1518, Mycobacterium abscessus 21, Mycobacterium abscessus MAB_020201_1061, Mycobacterium abscessus MAB_020201_1075, Mycobacterium abscessus MAB_110811_1470, Mycobacterium abscessus MAB_110811_2726, Mycobacterium abscessus 3A-0810-R, Mycobacterium abscessus 4S-0116-S, Mycobacterium abscessus 4S-0116-R, Mycobacterium abscessus 3A-0930-S, Mycobacterium abscessus 3A-0930-R, Mycobacterium abscessus 3A-0731, Mycobacterium abscessus 3A-0122-S, Mycobacterium abscessus 3A-0122-R, Mycobacterium abscessus 3A-0119-R, Mycobacterium abscessus 4S-0206, Mycobacterium abscessus 6G-0728-R, Mycobacterium abscessus 6G-0212, Mycobacterium abscessus 6G-0728-S, Mycobacterium abscessus 6G-1108, Mycobacterium abscessus 6G-0125-R, Mycobacterium abscessus 6G-0125-S, Mycobacterium abscessus 4S-0726-RA, Mycobacterium abscessus 4S-0726-RB, Mycobacterium abscessus 4S-0303 Bacteria UP000029491, UP000020509, UP000020103, UP000020348, UP000019854, UP000022209, UP000022212, UP000004545, UP000004895, UP000003308, UP000004127, UP000004609, UP000003230, UP000006017, UP000003854, UP000003687, UP000005461, UP000005181, UP000003720, UP000006257, UP000004882, UP000003464, UP000003660, UP000003156, UP000006440, UP000004040 576487015, 576482238, 576454412, 576401317, 576397329, 576378129, 576368544, 392244471, 392234780, 392222640, 392220210, 392218894, 392209554, 392205841, 392198093, 392195100, 392183708, 392169844, 392163742, 392128118, 392126114, 392113838, 392111189, 392069999, 392066448, 392064451 EUA80534.1, EUA75770.1, EUA48030.1, ETZ95286.1, ETZ91310.1, ETZ72227.1, ETZ62752.1, EIV69949.1, EIV60278.1, EIV48163.1, EIV45734.1, EIV44419.1, EIV35126.1, EIV31424.1, EIV23707.1, EIV20719.1, EIV09359.1, EIU95522.1, EIU89431.1, EIU53868.1, EIU51865.1, EIU39607.1, EIU36959.1, EIT95846.1, EIT92296.1, EIT90300.1 fig|1001720.3.peg.4408, fig|1001736.3.peg.4257, fig|1001716.3.peg.4270, fig|1001723.3.peg.4020, fig|1001737.3.peg.4458, fig|1001722.3.peg.4012, fig|1246644.3.peg.85, fig|36809.5.peg.4274, fig|1001719.3.peg.4334, fig|1176125.3.peg.2236, fig|1001727.3.peg.3558, fig|1162284.3.peg.1886, fig|1001724.3.peg.3112, fig|1001726.3.peg.3947, fig|1091046.3.peg.4123, fig|1149134.5.peg.4675, fig|1001740.3.peg.3290, fig|1001725.3.peg.4020, fig|1175632.3.peg.4285, fig|1001715.3.peg.4493, fig|1001738.3.peg.4465, fig|1001718.3.peg.4535, fig|1158135.4.peg.233, fig|1001721.3.peg.4457, fig|1001739.3.peg.4277, fig|1001741.3.peg.4518, fig|1001717.3.peg.4460 514 514 yes 1891772 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217706 Acinetobacter sp. NIPH 2168 Bacteria UP000013173 491397707, 480187559 ENX23831.1 WP_005255554.1 fig|1217706.3.peg.418 626 631 yes 1891773 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1390, 1114958 Bacillus amyloliquefaciens, Bacillus amyloliquefaciens subsp. plantarum CAU B946 Bacteria UP000027101, UP000008361 504070670, 641403329, 371567545 KDN91374.1 WP_014304664.1 fig|999407.4.peg.2621, fig|997896.4.peg.4890, fig|997894.4.peg.2602, fig|411902.9.peg.2812, fig|997897.5.peg.2455, fig|997895.4.peg.1025, fig|997893.5.peg.852 590 590 yes 1891774 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 108980, 1257043 Acinetobacter ursingii, Acinetobacter ursingii ANC 3649 Bacteria UP000013276 491143419, 480041014 ENV80501.1 WP_005001820.1 fig|1257043.3.peg.644 626 638 yes 1891775 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1099853, 1349822 Barnesiella sp. NSB1, Coprobacter fastidiosus NSB1 Bacteria UP000016962 550265817, 548784968 ERM89342.1 WP_022600903.1 565 565 yes 1891776 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34073, 1246301 Variovorax paradoxus, Variovorax paradoxus B4 Bacteria UP000050323, UP000016223 540273471, 537387585 AGU51958.1 WP_021012608.1 624 628 yes 1891777 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1773, 1324261 Mycobacterium tuberculosis, Mycobacterium tuberculosis TKK-01-0051 Bacteria UP000065426, UP000025947 764894729, 625016615 KBZ68327.1 WP_044483599.1 543 551 yes 1891778 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 862751 Streptomyces sp. SA3_actE Bacteria UP000001397 503813212, 344316538 AEN11226.1 WP_014047206.1 593 603 yes 1891779 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 600 608 yes 1891780 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 754477 Methylophaga sp. JAM7 Bacteria UP000009145 504515668, 386270406 AFJ01320.1 WP_014702770.1 fig|754477.3.peg.138 600 602 yes 1891781 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 517697380 WP_018867588.1 627 629 yes 1891782 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1145177, 1069618, 604162 Neisseria meningitidis, Neisseria meningitidis NM134, Neisseria meningitidis 92045, Neisseria meningitidis 8013 Bacteria UP000050419, UP000014639, UP000005016, UP000002076 488168905, 514068045, 402334145, 261393365 EPF53069.1, EJU69439.1 WP_002240113.1 fig|604162.3.peg.2601, fig|1069618.3.peg.2678, fig|1145177.3.peg.2591 625 633 yes 1891783 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 488, 435832 Neisseria mucosa, Neisseria mucosa C102 Bacteria UP000029875, UP000003612 489844223, 317399752 EFV80415.1 WP_003747918.1 624 629 yes 1891784 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1053687 Neisseria meningitidis NM220 Bacteria UP000005400 372199803 EHP13987.1 fig|1053687.3.peg.2130 625 648 yes 1891785 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262792 Clostridium sp. CAG:299 Environmental samples UP000017929 547943654, 524621998 WP_022344839.1 445 448 yes 1891786 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2252, 523841 Haloferax mediterranei, Haloferax mediterranei ATCC 33500 Archaea UP000011603 490160943, 631805567, 445747978 AHZ23263.1, ELZ99428.1 WP_004059605.1 M0IUD4 M0IUD4_HALMT 440 471 yes 1891787 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43263, 1215092 Pseudomonas alcaligenes, Pseudomonas alcaligenes NBRC 14159 Bacteria UP000016560 545464432, 543437605 WP_021701041.1 627 627 yes 1891788 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1166016 Pectobacterium sp. SCC3193 Bacteria UP000008044 504511385, 385869842 AFI88362.1 WP_014698487.1 fig|1166016.3.peg.235 631 646 yes 1891789 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1097676 Pseudoalteromonas sp. BSi20429 Bacteria UP000003479 494858929, 358035499 WP_007585029.1 fig|1097676.3.peg.2802 645 650 yes 1891790 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217692 Acinetobacter sp. NIPH 298 Bacteria UP000018428 491336743, 480160101 ENW96938.1 WP_005194699.1 fig|1217692.3.peg.739 626 631 yes 1891791 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1426, 1223501 Geobacillus thermoglucosidasius, Geobacillus thermoglucosidasius NBRC 107763 Bacteria UP000033360, UP000024871 755031191, 794552888, 617767609 KJX70149.1 WP_042383901.1 573 573 yes 1891792 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3694 Populus trichocarpa Plants UP000006729 UP000006729 566186318, 566186316, 566186314, 550331040, 550331039, 550331038 EEE88076.2, ERP56838.1, ERP56837.1 XP_002314121.2, XP_006379041.1, XP_006379040.1 553 637 yes 1891793 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 157687 Leptotrichia wadei Bacteria 517312430 WP_018499108.1 433 433 yes 1891794 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2426, 377629 Teredinibacter turnerae, Teredinibacter turnerae T7901 Bacteria UP000009080 506300938, 237687335, 259518359 ACR14599.1 WP_015820713.1 C5BTK7 THIC_TERTT Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 7056453 fig|377629.3.peg.3663, fig|1073969.3.peg.4129 638 639 yes 1891795 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1768, 1299328, 1299326, 557599 Mycobacterium kansasii, Mycobacterium kansasii 824, Mycobacterium kansasii 662, Mycobacterium kansasii ATCC 12478 Bacteria UP000027649, UP000031745, UP000031766, UP000017786 556614138, 690333631, 690322093, 660932912, 576422001, 576410093, 556024742 AIR29299.1, AIR19720.1, KEP44245.1, EUA15747.1, EUA03892.1, AGZ51953.1 WP_023370252.1 545 548 yes 1891796 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262889 Eubacterium sp. CAG:38 Environmental samples UP000017954 548213541, 524735654 WP_022433002.1 434 435 yes 1891797 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116081 Escherichia coli, Escherichia coli P0305260.7 Bacteria UP000036210, UP000012238 487381058, 477343103 ENG12171.1 WP_001653596.1 fig|1116081.3.peg.4241 626 631 yes 1891798 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 869213 Cytophaga fermentans DSM 9555 Bacteria UP000019402 588492081 223 223 no 1891799 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 869213 Cytophaga fermentans DSM 9555 Bacteria UP000019402 588492080 197 197 no 1891800 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 379347, 1265309 Ruegeria mobilis, Ruegeria mobilis F1926 Bacteria UP000033703, UP000013243 491918343, 798778079, 481054997 KJZ24008.1, ENZ88999.1 WP_005671381.1 fig|1265309.4.peg.4219 596 604 yes 1891801 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 582419 Thermococcus sp. ES1 Archaea UP000019027 757128190, 573025824 AHF81358.1 WP_042682522.1 W0IA92 W0IA92_9EURY 429 429 yes 1891802 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2426 Teredinibacter turnerae Bacteria 516642339 WP_018013918.1 638 639 yes 1891803 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 882944, 882102 Listonella anguillarum M3, Listonella anguillarum 775 Bacteria UP000017459, UP000006800 537379273, 335340552 AGU56509.1, AEH31835.1 fig|882102.3.peg.245 641 684 yes 1891804 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 625 634 yes 1891805 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54308, 118163 Pleurocapsa minor, Pleurocapsa sp. PCC 7327 Bacteria UP000010382 504957723, 427980926 AFY78526.1 WP_015144825.1 fig|118163.3.peg.3680 457 458 yes 1891806 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 390884, 926556 Echinicola vietnamensis, Echinicola vietnamensis DSM 17526 Bacteria UP000010796 505080226, 430789654 AGA79783.1 WP_015267328.1 fig|926556.3.peg.3754 623 623 yes 1891807 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1407059 Pseudomonas aeruginosa PA38182 Bacteria UP000019224 575876356 536 582 no 1891808 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1295609, 795359 Thermodesulfobacterium geofontis, Thermodesulfobacterium sp. OPB45 Bacteria UP000006583 503675024, 334901594 AEH22400.1 WP_013909100.1 fig|795359.3.peg.287 441 442 yes 1891809 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61645, 640513 Enterobacter asburiae, Enterobacter asburiae LF7a Bacteria UP000036088, UP000008527 503834466, 345091348 AEN62984.1 WP_014068460.1 fig|640513.3.peg.388 626 631 yes 1891810 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 293387, 1178544 Bacillus altitudinis, Bacillus altitudinis 41KF2b Bacteria UP000030841, UP000026881 737733401, 635187563 KDE31466.1 WP_035702165.1 586 586 yes 1891811 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1111133 Clostridiales bacterium BV3Ac2 Bacteria UP000017087 553314302, 551693071 ERT64524.1 WP_023059200.1 436 438 yes 1891812 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 359408 Methylotenera mobilis Bacteria 518737151 WP_019896733.1 624 627 yes 1891813 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1396, 1405 Bacillus cereus, Bacillus mycoides Bacteria UP000036076, UP000035933 517611053, 753709255, 673974957 AJI19376.1, AIK37947.1 WP_018781261.1 586 586 yes 1891814 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423, 1227747, 645657 Bacillus subtilis, Bacillus subtilis Miyagi-4, Bacillus subtilis subsp. natto BEST195 Bacteria UP000030083, UP000029002, UP000006805 504292130, 675434347, 291483325 WP_014479232.1 590 590 yes 1891815 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 212663 Vibrio tasmaniensis Bacteria 515670736 WP_017103336.1 640 649 yes 1891816 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287226 Mesorhizobium sp. LNHC209A00 Bacteria UP000021677 563806239, 563165869 ESY89288.1 WP_023796534.1 596 611 yes 1891817 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 456163 Thermus sp. RLM Bacteria UP000053186 495907495, 380451653 EIA39255.1 WP_008632074.1 433 435 yes 1891818 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992184, 992153, 992148, 992134 Yersinia pestis, Yersinia pestis PY-103, Yersinia pestis PY-48, Yersinia pestis PY-36, Yersinia pestis PY-08 Bacteria UP000000815 UP000031825, UP000004817, UP000005718, UP000004173, UP000003231 488315075, 391723065, 391550679, 391531835, 391453722 EIT52803.1, EIS00271.1, EIR83293.1, EIR13007.1 WP_002384460.1 204 223 no 1891819 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 274, 798128 Thermus thermophilus, Thermus thermophilus JL-18 Bacteria UP000007388 504442786, 383509845 AFH39277.1 WP_014629888.1 fig|798128.4.peg.1359 433 435 yes 1891820 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 398743, 655815 Zunongwangia profunda, Zunongwangia profunda SM-A87 Bacteria UP000001654 502834677, 294980035 ADF50500.1 WP_013069653.1 fig|655815.4.peg.134 616 618 yes 1891821 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262698 Alistipes sp. CAG:831 Environmental samples UP000018094 547185643, 524053588 WP_021927593.1 577 577 yes 1891822 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 948, 1269275 Anaplasma phagocytophilum, Anaplasma phagocytophilum CRT38 Bacteria UP000033356, UP000053165 546157695, 482614396 EOA62132.1 WP_021799566.1 557 557 yes 1891823 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406, 886882, 1052684 Paenibacillus polymyxa, Paenibacillus polymyxa SC2, Paenibacillus polymyxa M1 Bacteria UP000031922, UP000006868, UP000001644 503134759, 309245217, 343095469 ADO54784.1 WP_013369420.1 fig|886882.3.peg.775, fig|1406.5.peg.755 595 604 yes 1891824 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 566 567 yes 1891825 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2322, 644295 Methanohalobium evestigatum, Methanohalobium evestigatum Z-7303 Archaea UP000000391 502958595, 298674049, 298287037 ADI73003.1 WP_013193571.1, YP_003725799.1 D7E5Y1 D7E5Y1_METEZ 406 419 no 1891826 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 1495331, 911240, 911244, 1037911 Pseudomonas sp. WCS374, Pseudomonas sp. CF150, Pseudomonas sp. CFT9, Pseudomonas fluorescens A506 Bacteria UP000027026, UP000014881, UP000014857, UP000002879 504529545, 646237579, 515463872, 515434524, 387161542 AIB39938.1, EPL12374.1, EPJ82676.1, AFJ56741.1 WP_014716647.1 fig|1037911.3.peg.479 627 629 yes 1891827 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 158080, 290398 Chromohalobacter salexigens, Chromohalobacter salexigens DSM 3043 Bacteria UP000000239 499825528, 91796177 ABE58316.1 WP_011506262.1 fig|290398.11.peg.978 631 633 yes 1891828 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 698759 Streptomyces ipomoeae 91-03 Bacteria UP000010411 428662814 EKX62218.1 fig|698759.3.peg.7083 589 608 yes 1891829 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 592 592 yes 1891830 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29507, 1049966 Leptospira kirschneri, Leptospira kirschneri str. H1 Bacteria UP000006253 490903650, 409956635 EKO15557.1 WP_004765572.1 436 490 yes 1891831 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 208441, 1284240 Amycolatopsis decaplanina, Amycolatopsis decaplanina DSM 44594 Bacteria UP000054226 494092602, 452949143 EME54614.1 WP_007033430.1 fig|1284240.4.peg.5717 545 547 yes 1891832 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992175, 992163 Yersinia pestis, Yersinia pestis PY-93, Yersinia pestis PY-63 Bacteria UP000000815 UP000031825, UP000004737, UP000003774 488354068, 391675576, 391610299 EIT10077.1, EIS52603.1 WP_002423453.1 208 227 no 1891833 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 272563, 1002369, 997827, 997828, 1496, 1215086, 1215085, 1215084, 1215083, 1215082, 1215081, 1215080, 1215079, 1215078, 1215076, 1215075, 1215074, 1215073, 1215072, 1215071, 1215070, 1215069, 1215068, 1215067, 1215066, 1215064, 1215065, 1215063, 1215062, 645463, 645462 Clostridium difficile 630, Clostridium difficile 70-100-2010, Clostridium difficile 002-P50-2011, Clostridium difficile 050-P50-2011, Clostridium difficile, Clostridium difficile T61, Clostridium difficile T14, Clostridium difficile T10, Clostridium difficile T19, Clostridium difficile E12, Clostridium difficile E23, Clostridium difficile E28, Clostridium difficile T3, Clostridium difficile E7, Clostridium difficile T17, Clostridium difficile E14, Clostridium difficile T6, Clostridium difficile T42, Clostridium difficile E24, Clostridium difficile E19, Clostridium difficile T23, Clostridium difficile E15, Clostridium difficile T11, Clostridium difficile T15, Clostridium difficile E25, Clostridium difficile T22, Clostridium difficile E16, Clostridium difficile CD002, Clostridium difficile E13, Clostridium difficile R20291, Clostridium difficile CD196 Bacteria UP000032222, UP000005183, UP000005503, UP000004108, UP000058232, UP000018270, UP000018239, UP000018307, UP000017927, UP000017910, UP000018391, UP000018108, UP000018012, UP000018349, UP000017922, UP000018222, UP000018164, UP000017933, UP000018301, UP000018286, UP000018250, UP000018285, UP000018097, UP000018317, UP000017994, UP000018229, UP000017953, UP000018379, UP000018351, UP000002070, UP000015885 760238777, 357555079, 357544418, 357542863, 777204476, 662239378, 662028349, 662025951, 549393664, 549390645, 549386699, 549382919, 549378749, 549374958, 549370960, 549366893, 549362700, 549353950, 549350263, 549345946, 549340412, 549336641, 549333884, 549329927, 549325724, 549321246, 549316776, 549312228, 549308195, 549302785, 549299155, 549296469, 260212978, 260209530 AJP11416.1, EHJ36772.1, EHJ26422.1, EHJ24898.1 fig|479834.4.peg.1171, fig|499176.4.peg.1292, fig|997828.4.peg.3746, fig|691160.5.peg.2264, fig|645462.3.peg.1703, fig|645463.3.peg.1705, fig|455631.3.peg.3557, fig|272563.8.peg.1780, fig|367459.5.peg.819, fig|479833.4.peg.1315, fig|1125976.4.peg.3482, fig|479832.7.peg.1316, fig|699037.5.peg.1845, fig|699033.6.peg.1737, fig|997827.4.peg.3100, fig|479831.4.peg.953, fig|699036.5.peg.1775, fig|699034.5.peg.1734, fig|1121308.3.peg.2154, fig|499175.4.peg.1345, fig|691161.5.peg.1456, fig|1002369.4.peg.2802 459 471 yes 1891834 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1348563 Salmonella enterica, Salmonella enterica subsp. enterica serovar Namur str. 05-2929 Bacteria UP000054489, UP000019600 685237917, 595745050 EXX80046.1 WP_031606150.1 626 631 yes 1891835 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992150 Yersinia pestis, Yersinia pestis PY-45 Bacteria UP000000815 UP000031825, UP000003090 488348034, 391536958 EIR87890.1 WP_002417419.1 179 206 no 1891836 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1209355 Acinetobacter sp. MDS7A Bacteria 518676432 WP_019838125.1 626 631 yes 1891837 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 51197, 645991 Syntrophobotulus glycolicus, Syntrophobotulus glycolicus DSM 8271 Bacteria UP000007488 503390161, 324965175 ADY55954.1 WP_013624822.1 fig|645991.3.peg.1793 432 433 yes 1891838 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 244366, 640131 Klebsiella variicola, Klebsiella variicola At-22 Bacteria UP000037523, UP000001907 502734194, 288892419 ADC60737.1 WP_012969178.1 fig|640131.3.peg.4834 626 631 yes 1891839 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281213 Escherichia coli, Escherichia coli UMEA 3200-1 Bacteria UP000036210, UP000016357 545277525, 535646717 EQX82909.1 WP_021564772.1 626 631 yes 1891840 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 519083170 WP_020239045.1 626 631 yes 1891841 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 153948 Nitrosomonas sp. AL212 Bacteria UP000001629 503414221, 325533225 ADZ27946.1 WP_013648882.1 fig|153948.3.peg.23 626 631 yes 1891842 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83656, 1114943 Streptomyces tsukubaensis, Streptomyces tsukubaensis NRRL18488 Bacteria UP000005940 493391932, 385667620 EIF91025.1 WP_006348093.1 fig|1114943.5.peg.3632 592 603 yes 1891843 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29321, 883169 Turicella otitidis, Turicella otitidis ATCC 51513 Bacteria UP000033941, UP000011016 490737718, 404387859, 394487944 EJZ82954.1 WP_004600026.1 fig|883169.3.peg.130 593 599 yes 1891844 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281171, 1280961, 1182686, 1182685, 1169329 Escherichia coli, Escherichia coli KOEGE 118 (317a), Escherichia coli HVH 6 (3-8296502), Escherichia coli KTE79, Escherichia coli KTE78, Escherichia coli KTE9 Bacteria UP000036210, UP000016415, UP000016409, UP000010666, UP000010596, UP000010593 486308933, 535456682, 534555510, 431347394, 431334664, 431269400 EQV96815.1, EQN15104.1, ELG34283.1, ELG21818.1, ELF60752.1 WP_001577511.1 fig|1182685.3.peg.4615, fig|1182686.3.peg.1503, fig|1169329.3.peg.230 626 631 yes 1891845 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173, 1193041 Leptospira interrogans, Leptospira interrogans str. HAI1536 Bacteria UP000037872, UP000012112 488106473, 464382503 EMO54117.1 WP_002177870.1 477 496 yes 1891846 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2378, 1123288, 411922 Sporomusa ovata, Sporomusa ovata DSM 2662, Sporomusa sp. An4 Bacteria UP000015521, UP000049855 544737967, 530352761, 808678135 EQB28718.1 WP_021166866.1 431 432 yes 1891847 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217698 Acinetobacter sp. NIPH 3623 Bacteria UP000013200 491423217, 480204954 ENX40759.1 WP_005281013.1 fig|1217698.3.peg.226 626 631 yes 1891848 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1385369 Skermanella stibiiresistens SB22 Bacteria UP000019486 587641265 EWY40280.1 609 610 yes 1891849 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116067, 1116072 Escherichia coli, Escherichia coli P0301867.3, Escherichia coli P0301867.11 Bacteria UP000036210, UP000012255, UP000012188 485893320, 477429302, 477002211 ENG93842.1, ENC88230.1 WP_001485170.1 fig|1116067.3.peg.4493, fig|1116072.3.peg.4495 626 631 yes 1891850 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53462, 1209984 Mycobacterium mageritense, Mycobacterium mageritense DSM 44476 Bacteria UP000028867 738479497, 602544198 WP_036429716.1 527 533 yes 1891851 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106590, 1042878 Cupriavidus necator, Cupriavidus necator N-1 Bacteria UP000053399, UP000006798 503721239, 338164536 AEI75591.1 WP_013955315.1 fig|1042878.5.peg.3143 624 626 yes 1891852 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 536231 Roseburia intestinalis L1-82 Bacteria UP000004828 257201340 EEU99624.1 449 469 yes 1891853 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47951, 1136163 Vibrio cyclitrophicus, Vibrio cyclitrophicus FF75 Bacteria UP000016872 515161046, 548712868 ERM58974.1 WP_016789610.1 640 649 yes 1891854 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053239 Bacillus cereus, Bacillus cereus VD156 Bacteria UP000036076, UP000006978 446737237, 401281838 EJR87743.1 WP_000814493.1 fig|1053239.3.peg.350 586 586 yes 1891855 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053167, 1053172 Bacillus cereus, Bacillus cereus BAG1O-1, Bacillus cereus BAG1X1-3 Bacteria UP000036076, UP000013998, UP000006993 446737235, 500353044, 401643058 EOO70876.1, EJS60762.1 WP_000814491.1 fig|1053172.3.peg.368, fig|1053167.3.peg.5926 586 586 yes 1891856 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053194, 1053180 Bacillus cereus, Bacillus cereus BAG6X1-1, Bacillus cereus BAG2X1-2 Bacteria UP000036076, UP000004381, UP000006963 446737233, 402425668, 401656570 EJV57814.1, EJS74085.1 WP_000814489.1 fig|1053194.3.peg.4888, fig|1053180.3.peg.348 586 586 yes 1891857 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 180957 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. brasiliensis Bacteria UP000053038, UP000032867 497971361, 684983850 KGA22019.1 WP_010285517.1 631 651 yes 1891858 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053181 Bacillus cereus, Bacillus cereus BAG2X1-3 Bacteria UP000036076, UP000006975 446737230, 401661068 EJS78538.1 WP_000814486.1 fig|1053181.3.peg.136 586 586 yes 1891859 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1160137 Nocardia sp. BMG111209 Bacteria 518770522 WP_019927811.1 413 418 no 1891860 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1306990 Streptomyces sp. R1-NS-10 Bacteria 517903194 WP_019073402.1 591 612 yes 1891861 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285679, 1150864 Micromonospora lupini, Micromonospora lupini str. Lupac 08 Bacteria UP000003448 494729333, 385882645 WP_007465199.1 fig|1150864.3.peg.5782 530 530 yes 1891862 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76831, 1583100, 883150, 883154, 883152 Myroides sp. A21, Myroides odoratimimus CCUG 10230, Myroides odoratimimus CIP 101113, Myroides odoratimimus CCUG 12901 Bacteria UP000031291, UP000005402, UP000004834, UP000003740 493302145, 736012973, 371641105, 371639679, 371639447 AJA68027.1, EHO06692.1, EHO05294.1, EHO05063.1 WP_006259739.1 fig|883154.3.peg.3303, fig|883150.3.peg.2843, fig|883152.3.peg.3350 604 604 yes 1891863 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2221, 1090322 Methanolobus tindarius, Methanolobus tindarius DSM 2278 Archaea 564601265, 563513701 ETA69075.1 WP_023846209.1 W9DTZ2 W9DTZ2_METTI 427 427 yes 1891864 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1214102 Mycobacterium fortuitum subsp. fortuitum DSM 46621 Bacteria UP000053406 403653465 EJZ08444.1 fig|1214102.3.peg.4800 530 531 yes 1891865 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1486991, 2342 Candidatus Sodalis pierantonius, primary endosymbiont of Sitophilus oryzae Bacteria UP000019025 643661003, 573019263 AHF74800.1 WP_025246535.1 594 608 yes 1891866 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 561879, 1178541 Bacillus safensis, Bacillus safensis FO-36b Bacteria UP000032451, UP000026882 736148405, 807225112, 635185208 KKD43280.1, KDE29123.1 WP_034279875.1 586 586 yes 1891867 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1305740, 626887 Marinobacter nanhaiticus, Marinobacter sp. D15-8W Bacteria UP000013165 490718248, 478767998 ENO12583.1 WP_004580813.1 fig|626887.3.peg.2857 624 626 yes 1891868 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1142394 Phycisphaera mikurensis NBRC 102666 Bacteria UP000007881 381388311 485 569 yes 1891869 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287292 Mesorhizobium sp. LSHC420B00 Bacteria UP000018524 563499155, 563058399 ESX83329.1 WP_023717067.1 596 611 yes 1891870 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262462 Yersinia enterocolitica (type O:5) str. YE53/03 Bacteria UP000032730 571260501 617 633 yes 1891871 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116075, 1116123 Escherichia coli, Escherichia coli P0302293.4, Escherichia coli 2726950 Bacteria UP000036210, UP000012358, UP000012298 486265810, 477148885, 476743602 ENE26824.1, ENA47915.1 WP_001567191.1 fig|1116123.3.peg.4577, fig|1116075.3.peg.4774 626 631 yes 1891872 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1337093 Loktanella cinnabarina LL-001 Bacteria UP000016566 543421239 599 603 yes 1891873 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29438, 875330, 875329 Pseudomonas savastanoi, Pseudomonas syringae pv. glycinea str. race 4, Pseudomonas syringae pv. glycinea str. B076 Bacteria UP000037867, UP000032703, UP000002992 490792399, 330872218, 320330982, 320321912 EGH06367.1, EFW86956.1, EFW78008.1 WP_004654545.1 fig|875330.5.peg.1239, fig|875329.4.peg.4727 627 629 yes 1891874 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1465809 Clostridium senegalense Bacteria 497982481 WP_010296637.1 436 436 yes 1891875 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 910039 candidate division OP8 bacterium SCGC AAA252-K06 Bacteria 551131180 WP_022809581.1 216 216 no 1891876 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1306162 Xenorhabdus nematophila F1 Bacteria UP000013496 484361128 fig|1306162.3.peg.2942 625 663 yes 1891877 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 287, 1441461, 1441460, 1447541, 1457392, 1402529, 1402531, 1402534, 1402539, 1402541, 1279008, 1279007, 1402488, 1402547, 1402546, 1402553, 1402565, 1402485, 1402499, 1402502, 1402503, 1402517, 1402552, 1402571, 1402577, 1402578, 1402579, 1402580, 1125698, 941193, 1078464 Pseudomonas aeruginosa, Pseudomonas aeruginosa C0324C, Pseudomonas aeruginosa C1913C, Pseudomonas aeruginosa BWH033, Pseudomonas aeruginosa PA96, Pseudomonas aeruginosa BWHPSA037, Pseudomonas aeruginosa BWHPSA039, Pseudomonas aeruginosa BWHPSA042, Pseudomonas aeruginosa BWHPSA047, Pseudomonas aeruginosa Z61, Pseudomonas aeruginosa PA1R, Pseudomonas aeruginosa PA1, Pseudomonas aeruginosa CF127, Pseudomonas aeruginosa BL06, Pseudomonas aeruginosa BL05, Pseudomonas aeruginosa BL12, Pseudomonas aeruginosa BL24, Pseudomonas aeruginosa 62, Pseudomonas aeruginosa S35004, Pseudomonas aeruginosa BWHPSA002, Pseudomonas aeruginosa BWHPSA003, Pseudomonas aeruginosa BWHPSA017, Pseudomonas aeruginosa BL11, Pseudomonas aeruginosa M9A.1, Pseudomonas aeruginosa C51, Pseudomonas aeruginosa C52, Pseudomonas aeruginosa CF77, Pseudomonas aeruginosa CF614, Pseudomonas sp. P179, Pseudomonas aeruginosa M18, Pseudomonas aeruginosa NCMG1179 Bacteria UP000065817, UP000027627, UP000027908, UP000024047, UP000023757, UP000020020, UP000021496, UP000021726, UP000019952, UP000021893, UP000017804, UP000017802, UP000017297, UP000017400, UP000017333, UP000017558, UP000017299, UP000017581, UP000017427, UP000017460, UP000017514, UP000017516, UP000017359, UP000017411, UP000017416, UP000017286, UP000017526, UP000017340, UP000017055, UP000009043, UP000003984 489253259, 763862832, 674746471, 653212157, 653190741, 611778602, 610418522, 574083524, 574075423, 574046765, 574016973, 573996742, 557712596, 557706796, 552724688, 552636610, 552626202, 552621884, 552585165, 552519330, 552469068, 552441294, 552439771, 552390477, 552279621, 552226315, 552193847, 552185652, 552178263, 552170431, 476645251, 347307450, 814549914, 675291654, 346060681 KJC22303.1, KFL13432.1, KEA31329.1, KEA11881.1, EZN55935.1, AHW73713.1, ETV59987.1, ETV51936.1, ETV23408.1, ETU93742.1, ETU73616.1, AHA24622.1, AHA18823.1, ERZ38075.1, ERY51131.1, ERY42648.1, ERY38369.1, ERY01853.1, ERX76213.1, ERX26590.1, ERW99210.1, ERW97695.1, ERW49038.1, ERV39683.1, ERU87309.1, ERU54696.1, ERU46612.1, ERU39300.1, ERU31679.1, EMZ51628.1, AEO77564.1 WP_003161275.1 fig|1193501.3.peg.1774, fig|1078464.3.peg.5435, fig|1208103.3.peg.57, fig|1168061.3.peg.2636, fig|941193.4.peg.5261 627 627 yes 1891878 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 261965 Kangiella aquimarina Bacteria 517452755 WP_018623550.1 621 627 yes 1891879 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 870903, 401053 Terriglobus saanensis, Acidobacterium sp. SP1PR4 Bacteria UP000006844 503333642, 319925495 ADV82570.1 WP_013568303.1 fig|401053.3.peg.1894 489 492 yes 1891880 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 657313 Ruminococcus torques L2-14 Bacteria UP000008956 291550800 435 436 yes 1891881 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 1339296, 1339297, 1339335 Bacteroides fragilis, Bacteroides fragilis str. 1009-4-F #7, Bacteroides fragilis str. 1009-4-F #10, Bacteroides fragilis str. 3-F-2 #6 Bacteria UP000036847, UP000020858, UP000020619, UP000019827 695482737, 596184367, 596178158, 596116915 EYA34312.1, EYA28542.1, EXZ78119.1 WP_032574377.1 564 564 yes 1891882 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 820, 997890, 997889 Bacteroides uniformis, Bacteroides uniformis CL03T12C37, Bacteroides uniformis CL03T00C23 Bacteria UP000006032, UP000005192 492414312, 392687007, 392677935 EIY80305.1, EIY71347.1 WP_005837102.1 fig|997889.3.peg.3887, fig|997890.3.peg.1328 560 560 yes 1891883 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 239974 Nocardiopsis sp. 20028 Bacteria 516151339 WP_017581919.1 553 555 yes 1891884 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 190898, 1286635 Desulfotignum phosphitoxidans, Desulfotignum phosphitoxidans DSM 13687 Bacteria UP000014216 494025477, 474486650 EMS78260.1 WP_006967691.1 fig|1286635.3.peg.3751 422 434 no 1891885 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543, 1444067, 1444039, 1286170, 883121 Escherichia coli 2-156-04_S1_C2, Escherichia coli 2-156-04_S1_C1, Raoultella ornithinolytica B6, Klebsiella oxytoca 10-5246 Bacteria UP000027694, UP000027660, UP000012982, UP000003031 490220068, 651835283, 651709977, 480478172, 376402465 KDX09586.1, KDV89689.1, AGJ88190.1, EHT15058.1 WP_004118441.1 fig|1286170.3.peg.3578, fig|883121.3.peg.23 626 631 yes 1891886 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1033802 Salinisphaera shabanensis E1L3A Bacteria UP000006242 543112594 ERJ20168.1 622 647 yes 1891887 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1310601, 1217716 Acinetobacter baumannii 479375, Acinetobacter ursingii NIPH 706 Bacteria UP000020573, UP000013054 491136909, 588052606, 480214140 EXD34164.1, ENX49795.1 WP_004995326.1 fig|1217716.3.peg.991 627 638 yes 1891888 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 827 Bacteroides ureolyticus Bacteria 517543123 WP_018713331.1 434 435 yes 1891889 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 252394 Actinoalloteichus spitiensis Bacteria 515069199 WP_016699078.1 549 554 yes 1891890 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 174, 1192866 Leptospira borgpetersenii, Leptospira borgpetersenii serovar Pomona str. 200901868 Bacteria UP000012159 488841693, 464394087 EMO62691.1 WP_002754099.1 511 511 yes 1891891 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 1328428, 883117 Klebsiella oxytoca, Klebsiella oxytoca MGH 27, Klebsiella oxytoca 10-5242 Bacteria UP000030350, UP000020202, UP000005152 490199158, 583731606, 376379739 EWF93509.1, EHS92490.1 WP_004097665.1 fig|883117.3.peg.4541 626 631 yes 1891892 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3885 Phaseolus vulgaris Plants UP000000226 593692386, 593692384, 561019958, 561019957 ESW18729.1, ESW18728.1 XP_007146735.1, XP_007146734.1 542 650 yes 1891893 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34078 Scytonema hofmanni Bacteria 516355111 WP_017745144.1 455 458 yes 1891894 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1069619, 663926 Neisseria meningitidis, Neisseria meningitidis NM2657, Neisseria meningitidis alpha153 Bacteria UP000050419, UP000003129 488169628, 402335465, 254671196 EJU70730.1 WP_002240836.1 fig|1069619.3.peg.2567 625 633 yes 1891895 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298865 Alteromonas sp. ALT199 Bacteria UP000022887 643753779, 588497428 EXF50726.1 WP_025257021.1 630 636 yes 1891896 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1266913 Thioalkalivibrio sp. HL-Eb18 Bacteria 516538854 WP_017926479.1 627 629 yes 1891897 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 638 Arsenophonus nasoniae Bacteria 284009054 582 586 yes 1891898 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 202952, 1330037, 1120926 Acinetobacter gerneri, Acinetobacter gerneri MTCC 9824, Acinetobacter gerneri DSM 14967 = CIP 107464 Bacteria UP000014964, UP000013117 491006390, 523902928, 479989389 EPR85250.1, ENV32383.1 WP_004868110.1 fig|1120926.3.peg.3666 624 628 yes 1891899 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413497, 1208656 Cronobacter dublinensis, Cronobacter dublinensis 1210 Bacteria UP000009342 495001250, 426741392 WP_007727265.1 fig|1159554.4.peg.2510, fig|1208656.3.peg.3310 626 633 yes 1891900 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 532 534 yes 1891901 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 28144, 1124929 Salmonella enterica, Salmonella enterica subsp. enterica serovar Derby, Salmonella enterica subsp. enterica serovar Derby str. 626 Bacteria UP000054489, UP000037475, UP000017538 555248049, 852269417, 554289872 KMM40626.1, ESH25709.1 WP_023231857.1 626 631 yes 1891902 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 92938 Fischerella muscicola Bacteria 515352773 WP_016864254.1 459 460 yes 1891903 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1198116 Thermoplasmatales archaeon SCGC AB-539-N05 Archaea UP000053781 495717683, 471673765 EMR73472.1 WP_008442262.1 M7T9V6 M7T9V6_9EURY 102 102 no 1891904 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1288971 Clostridium ultunense Esp Bacteria UP000011752 452994464 fig|1288971.3.peg.1856 495 583 no 1891905 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 261292 Nitrosomonas sp. Is79A3 Bacteria UP000000501 503733402, 338807032 AEJ03274.1 WP_013967478.1 fig|261292.4.peg.3798 627 631 yes 1891906 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 58097, 1320309 Salmonella enterica, Salmonella enterica subsp. enterica serovar Bovismorbificans, Salmonella enterica subsp. enterica serovar Bovismorbificans str. 3114 Bacteria UP000054489, UP000046388, UP000018770 538468015, 803157379, 537739371 WP_021001005.1 626 631 yes 1891907 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1284393 Pseudomonas brenneri FH4 Bacteria UP000018860 696286364, 567640731 ETK16204.1 WP_032862087.1 627 629 yes 1891908 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 516593908 WP_017968947.1 601 607 yes 1891909 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1053230 Bacillus cereus, Bacillus cereus VD115 Bacteria UP000036076, UP000006604 446737202, 401252120 EJR58386.1 WP_000814458.1 fig|1053230.3.peg.4469 586 586 yes 1891910 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42422, 748449 Halobacteroides halobius, Halobacteroides halobius DSM 5150 Bacteria UP000010880 505139378, 433669940 AGB40755.1 WP_015326480.1 fig|748449.3.peg.741 428 428 yes 1891911 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1229205 Burkholderia phenoliruptrix BR3459a Bacteria UP000010105 407236321 AFT86520.1 644 647 yes 1891912 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 262489 delta proteobacterium MLMS-1 Bacteria UP000005853 494505246, 93451593 EAT02396.1 WP_007294706.1 fig|262489.4.peg.4360 439 444 yes 1891913 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 174633 Candidatus Kuenenia stuttgartiensis Bacteria 91201902 442 443 yes 1891914 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310605 Acinetobacter baumannii, Acinetobacter baumannii 348935 Bacteria UP000028632, UP000020680 736699864, 587770169 EXA64311.1 WP_034705357.1 626 631 yes 1891915 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 521002 Methanobrevibacter smithii DSM 2374 Archaea 288860548 EFC92846.1 D2ZNJ9 D2ZNJ9_METSM 428 428 yes 1891916 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 490 Neisseria sicca Bacteria 515029225 WP_016686479.1 625 633 yes 1891917 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 551760, 76114 Aromatoleum aromaticum, Aromatoleum aromaticum EbN1 Bacteria UP000006552 499555990, 81598925, 56312403 WP_011236773.1 Q5P6L3 THIC_AROAE Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 814522 fig|76114.4.peg.254 638 638 yes 1891918 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1071390 Acinetobacter sp. NBRC 100985 Bacteria UP000012044 494744777, 358236225 WP_007480185.1 fig|1071390.3.peg.923 626 631 yes 1891919 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1255310 Erwinia amylovora MR1 Bacteria UP000013062 478730026 fig|1255310.3.peg.293 613 621 yes 1891920 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310609 Acinetobacter baumannii, Acinetobacter baumannii 1289694 Bacteria UP000028632, UP000020275 691130979, 587797223 EXA89707.1 WP_032046201.1 621 625 yes 1891921 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1236, 579607, 579537, 43655 Spongiobacter sp. S2292, Pseudoalteromonas sp. S3431, Pseudoalteromonas citrea Bacteria UP000033537, UP000027097, UP000027154 696493469, 798783642, 633469557, 633466556 KJZ28786.1, KDC51282.1, KDC48557.1 WP_033031961.1 645 650 yes 1891922 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1163710, 1073999 Cronobacter condimenti, Cronobacter sp. 1330 Bacteria UP000067320 494939883, 426549059 WP_007665911.1 fig|1073999.4.peg.746 626 633 yes 1891923 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 170573, 904314 Staphylococcus pettenkoferi, Staphylococcus epidermidis VCU012 Bacteria UP000008944 488401771, 365230820 EHM71896.1 WP_002471156.1 fig|904314.5.peg.304 578 578 yes 1891924 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262948 Roseburia sp. CAG:471 Environmental samples UP000018367 548177302, 524689881 WP_022398772.1 435 436 yes 1891925 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 597 632 yes 1891926 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 387341, 797302 Halovivax ruber, Halovivax ruber XH-70 Archaea UP000010846 505113117, 433637926, 433289730 AGB15553.1 WP_015300219.1, YP_007283686.1 L0I9P7 L0I9P7_HALRX 452 477 yes 1891927 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1460244 Streptomyces sp. PCS3-D2 Bacteria UP000024240 740070794, 606221755 EYU68906.1 WP_037920315.1 596 598 yes 1891928 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 457416 Veillonella sp. 3_1_44 Bacteria UP000005761 495991101, 294454468 EFG22842.1 WP_008715680.1 434 434 yes 1891929 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 706434 Megasphaera micronuciformis F0359 Bacteria UP000003195 310620145 EFQ03716.1 440 444 yes 1891930 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1235811 Prevotella disiens JCM 6334 = ATCC 29426 Bacteria UP000016660 543970920 ERJ76936.1 533 533 yes 1891931 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 997881, 997880 Bacteroides fragilis, Bacteroides fragilis CL05T12C13, Bacteroides fragilis CL05T00C42 Bacteria UP000036847, UP000003917, UP000004948 492304404, 392696824, 392696561 EIY90012.1, EIY89753.1 WP_005803711.1 fig|997881.3.peg.4326, fig|997880.3.peg.4322 564 564 yes 1891932 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2250, 931277 Halococcus morrhuae, Halococcus morrhuae DSM 1307 Archaea 490153707, 445797048 EMA47532.1 WP_004052383.1 M0MPB3 M0MPB3_HALMO 449 481 yes 1891933 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 179636, 596154, 596153, 1603291 Alicycliphilus denitrificans, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans BC, Alicycliphilus sp. B1 Bacteria UP000007938, UP000006626, UP000032901 503285825, 329311948, 317118918, 781561673 AEB86363.1, ADV01407.1 WP_013520486.1 fig|596154.3.peg.4066, fig|596153.3.peg.2275 609 615 yes 1891934 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 108150, 580331 Thermoanaerobacter italicus, Thermoanaerobacter italicus Ab9 Bacteria UP000001552 502760815, 289528735 ADD03087.1 WP_012995799.1 fig|580331.4.peg.1890 431 432 yes 1891935 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 337, 1176492, 626418 Burkholderia glumae, Burkholderia glumae LMG 2196, Burkholderia glumae BGR1 Bacteria UP000030878, UP000032606, UP000002187 502216392, 779723642, 731976275, 237875882 AJY65089.1, KHJ62543.1, ACR28215.1 WP_012735103.1 fig|1176492.3.peg.3315, fig|626418.3.peg.3816 642 643 yes 1891936 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1264, 1341156 Ruminococcus albus, Ruminococcus albus SY3 Bacteria UP000021369 739430252, 593020642 EXM38116.1 WP_037290311.1 437 437 yes 1891937 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1220535 alpha proteobacterium IMCC14465 Bacteria UP000004836 495794145, 402510641 EJW20903.1 WP_008518724.1 639 642 yes 1891938 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 52765, 632335 Caldicellulosiruptor kristjanssonii, Caldicellulosiruptor kristjanssonii 177R1B Bacteria UP000009256 503197073, 312179716 ADQ39886.1 WP_013431734.1 418 420 yes 1891939 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 456455, 1046627 Bizionia argentinensis, Bizionia argentinensis JUB59 Bacteria UP000003730 495911145, 344048863 EGV44466.1 WP_008635724.1 fig|1046627.3.peg.741 619 619 yes 1891940 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 246167 Vibrio crassostreae Bacteria UP000049932 515635174 WP_017067774.1 640 649 yes 1891941 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262927 Prevotella sp. CAG:485 Environmental samples UP000018062 548184978, 524700368 WP_022406016.1 571 571 yes 1891942 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 548 Enterobacter aerogenes Bacteria UP000056714 518924025, 838626577, 838612646, 822734639 KLW10674.1, KLV96887.1, KLE94078.1 WP_020079900.1 626 631 yes 1891943 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 261299, 1403940 Clostridium bartlettii, Clostridium bartlettii DORA_8_9 Bacteria UP000018833 567936143, 566233817 ETI96215.1 WP_024037249.1 434 434 yes 1891944 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571 Klebsiella oxytoca Bacteria UP000030350 515201040 WP_016809152.1 626 631 yes 1891945 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28108, 1300257, 1300256, 1300255 Alteromonas macleodii, Alteromonas macleodii str. 'Ionian Sea U8', Alteromonas macleodii str. 'Ionian Sea U7', Alteromonas macleodii str. 'Ionian Sea U4' Bacteria UP000031168, UP000014904, UP000014906, UP000014908 522829969, 521339288, 521335198, 521330632 AGP91875.1, AGP88022.1, AGP83936.1 WP_020742626.1 636 642 yes 1891946 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935547, 266835 Mesorhizobium loti R7A, Mesorhizobium loti MAFF303099 Bacteria UP000053249, UP000000552 20804219 Q98AZ3 THIC_RHILO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 87191 fig|266835.1.peg.4496 607 619 yes 1891947 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1764 Mycobacterium avium Bacteria 518525646 WP_019695853.1 373 374 yes 1891948 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 60890, 1423144 Phaeobacter gallaeciensis, Phaeobacter gallaeciensis DSM 26640 Bacteria UP000018782 568329405, 568230430 AHD10321.1 WP_024097958.1 594 602 yes 1891949 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263001 Firmicutes bacterium CAG:114 Environmental samples UP000018090 547168929, 524045342 WP_021919558.1 437 437 yes 1891950 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43658, 1117318 Pseudoalteromonas rubra, Pseudoalteromonas rubra ATCC 29570 Bacteria UP000036850, UP000016480 498072095, 540288337 ERG46559.1 WP_010386251.1 645 650 yes 1891951 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1282362 Asticcacaulis sp. AC466 Bacteria UP000017826 557833979, 557343702 ESQ83336.1 WP_023458772.1 615 616 yes 1891952 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 890399 Candidatus Magnetoglobus multicellularis str. Araruama Bacteria 571792838 ETR73175.1 428 428 yes 1891953 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 405212, 521098 Alicyclobacillus acidocaldarius, Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 Bacteria UP000001917 502519668, 257479338 ACV59657.1 WP_012811890.1 fig|521098.4.peg.1352 572 573 yes 1891954 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158160 Thioalkalivibrio sp. AKL17 Bacteria 517777087 WP_018947295.1 626 629 yes 1891955 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 180 Leptospirillum ferrooxidans Bacteria 31747770 AAO38379.1 66 73 no 1891956 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 180 Leptospirillum ferrooxidans Bacteria 31747778 AAO38383.1 198 198 no 1891957 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 171, 1242991 Leptospira sp. serovar Kenya str. Sh9 Bacteria UP000011969 515128536, 463348166 EMK11704.1 WP_016757387.1 fig|1049773.3.peg.385, fig|1242991.3.peg.2079 352 391 yes 1891958 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 551 552 yes 1891959 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 552 1225 yes 1891960 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1131274 gamma proteobacterium SCGC AB-629-P17 Bacteria 517212354 WP_018401172.1 621 622 yes 1891961 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1177179 Alcanivorax hongdengensis A-11-3 Bacteria UP000010164 407767580 EKF76017.1 fig|1177179.3.peg.184 625 632 yes 1891962 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106654, 1343071 Acinetobacter genomosp. 13TU, Acinetobacter nosocomialis M2 Bacteria UP000051466, UP000018240 549995285, 546290515 ERL68901.1 WP_022575147.1 621 625 yes 1891963 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281278 Escherichia coli, Escherichia coli UMEA 4076-1 Bacteria UP000036210, UP000015995 545301517, 535909348 ERA40192.1 WP_021581309.1 626 631 yes 1891964 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 1334632, 294, 321846, 1390371 Pseudomonas fluorescens PICF7, Pseudomonas fluorescens, Pseudomonas simiae, Pseudomonas fluorescens EGD-AQ6 Bacteria UP000032732, UP000060991, UP000032100, UP000016504 497899492, 785764594, 761529850, 755324692, 542001927 AJZ93111.1, AJP50168.1, KIQ12311.1, ERH47893.1 WP_010213648.1 628 634 yes 1891965 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310716 Acinetobacter baumannii, Acinetobacter baumannii 1482820 Bacteria UP000028632, UP000020330 691058542, 589482212 EXH63324.1 WP_032002689.1 621 625 yes 1891966 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 195, 1183379 Campylobacter coli, Campylobacter coli RM4661 Bacteria UP000062643, UP000019430 644977988, 589293060 AHK76356.1 WP_025398742.1 429 430 yes 1891967 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1328450 Escherichia coli, Escherichia coli BIDMC 39 Bacteria UP000036210, UP000017508 556198152, 554972446 ESL17161.1 WP_023281600.1 626 631 yes 1891968 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354276, 550, 1439329, 1329840, 1400146 Enterobacter cloacae, Enterobacter cloacae MGH 53, Enterobacter sp. BIDMC 28, Enterobacter cloacae UCI 23 Bacteria UP000036177, UP000027300, UP000019973, UP000020051 695719336, 838681183, 838669372, 822825933, 771429892, 635783079, 578257810, 578242849 KLW64856.1, KLW53117.1, KLF84160.1, KJP60926.1, KDF64493.1, EUM17861.1, EUM02965.1 WP_032646854.1 626 631 yes 1891969 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 288965, 720554 Clostridium clariflavum, Clostridium clariflavum DSM 19732 Bacteria UP000005435 504021683, 359826339 AEV69112.1 WP_014255677.1 fig|720554.3.peg.2674 432 432 yes 1891970 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287752 Aurantimonas manganoxydans SI85-9A1 Bacteria UP000000321 90334654 EAS48434.1 fig|287752.3.peg.83, fig|314269.3.peg.82 606 638 yes 1891971 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537011 Prevotella copri DSM 18205 Bacteria UP000004477 281403903 EFB34583.1 570 587 yes 1891972 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1458426 Comamonadaceae bacterium B1 Bacteria UP000066014 780241923, 635598129 WP_045535605.1 636 643 yes 1891973 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2223, 990316 Methanosaeta concilii, Methanosaeta concilii GP6 Archaea UP000007807 503484624, 328928438 AEB68240.1 WP_013719285.1 F4BU42 F4BU42_METCG 429 429 yes 1891974 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 530 530 yes 1891975 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 244363, 662475 Haloarcula californiae, Haloarcula californiae ATCC 33799 Archaea 494348715, 445761146 EMA12395.1 WP_007190107.1 M0JXR6 M0JXR6_9EURY 454 480 yes 1891976 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 182337, 634500 Erwinia billingiae, Erwinia billingiae Eb661 Bacteria UP000008793 502965329, 299060691 WP_013200305.1 fig|634500.5.peg.536 631 644 yes 1891977 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33037, 655811 Anaerococcus vaginalis, Anaerococcus vaginalis ATCC 51170 Bacteria UP000003821 490977228, 256399018 EEU12631.1 WP_004838997.1 fig|655811.4.peg.301 431 431 yes 1891978 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262786 Clostridium sp. CAG:264 Environmental samples UP000018342 547203029, 524080479 WP_021944077.1 435 436 yes 1891979 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 356662 Leeia oryzae Bacteria 516892284 WP_018151311.1 614 615 yes 1891980 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 363265, 1002367 Prevotella stercorea, Prevotella stercorea DSM 18206 Bacteria UP000004407 495176210, 357557091 EHJ38654.1 WP_007901004.1 fig|1002367.3.peg.1598 527 527 yes 1891981 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 588 589 yes 1891982 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 910311 Eggerthella sp. HGA1 Bacteria UP000006450 325488000 EGC90437.1 470 474 yes 1891983 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1101190 Methylopila sp. M107 Bacteria 519023456 WP_020179331.1 616 621 yes 1891984 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 859, 1095747 Fusobacterium necrophorum, Fusobacterium necrophorum subsp. funduliforme ATCC 51357 Bacteria UP000005618 492768250, 386904993 EIJ69774.1 WP_005958401.1 fig|1095747.3.peg.1175 433 433 yes 1891985 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 501497 Thermodesulfatator sp. AT1325 Bacteria 551228518 WP_022852323.1 421 434 no 1891986 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444149, 1444213, 1444088, 1444170, 1444175, 1444117, 1444057, 1444217, 1444245, 1444247, 1444050 Escherichia coli, Escherichia coli 2-052-05_S3_C2, Escherichia coli 7-233-03_S4_C1, Escherichia coli 4-203-08_S1_C2, Escherichia coli 3-475-03_S3_C2, Escherichia coli 2-005-03_S3_C3, Escherichia coli 2-005-03_S3_C1, Escherichia coli 3-267-03_S1_C1, Escherichia coli 1-182-04_S4_C1, Escherichia coli 1-182-04_S4_C2, Escherichia coli 1-392-07_S4_C2, Escherichia coli 1-176-05_S1_C1 Bacteria UP000036210, UP000027757, UP000027669, UP000027930, UP000027769, UP000027874, UP000027925, UP000028108, UP000024117, UP000023948, UP000024056, UP000023224 692987877, 660281794, 660247270, 659991602, 659982747, 651787789, 651777541, 650094229, 611054952, 611034722, 611024939, 598672426 KEN71877.1, KEN38077.1, KEK90800.1, KEK82275.1, KDW64224.1, KDW54438.1, KDU15509.1, EZJ58267.1, EZJ38757.1, EZJ29459.1, EYD80580.1 WP_032176779.1 626 631 yes 1891987 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 309799 Dictyoglomus thermophilum H-6-12 Bacteria UP000001733 206739773 ACI18831.1 fig|309799.3.peg.1498 414 417 no 1891988 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29497 Vibrio splendidus Bacteria UP000050463 518658226 WP_019820037.1 640 649 yes 1891989 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 382, 1235461, 698936 Sinorhizobium meliloti, Sinorhizobium meliloti GR4, Sinorhizobium meliloti BL225C Bacteria UP000028953, UP000011869, UP000008709 504340614, 429555301, 333816315 AGA10221.1, AEG08982.1 WP_014527716.1 605 616 yes 1891990 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262965 Ruminococcus sp. CAG:624 Environmental samples UP000017977 548303885, 524806180 WP_022494925.1 437 437 yes 1891991 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 309887, 709986 Deinococcus maricopensis, Deinococcus maricopensis DSM 21211 Bacteria UP000008635 503322696, 319756095 ADV67852.1 WP_013557357.1 fig|709986.3.peg.2225 619 633 yes 1891992 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1665, 1077972 Arthrobacter globiformis, Arthrobacter globiformis NBRC 12137 Bacteria UP000003828 489902621, 359303654 WP_003806054.1 fig|1077972.3.peg.4125 595 614 yes 1891993 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 325240 Shewanella baltica OS155 Bacteria UP000001557 125997449 ABN61524.1 fig|325240.15.peg.2323 215 224 no 1891994 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 517346554 WP_018522046.1 595 597 yes 1891995 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 298654 Frankia sp. EuI1c Bacteria UP000002484 311229483 ADP82338.1 fig|298654.3.peg.5057 558 571 yes 1891996 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 963 516021446 WP_017452029.1 636 637 yes 1891997 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 184064, 747365 Thermodesulfobium narugense, Thermodesulfobium narugense DSM 14796 Bacteria UP000011765 503521543, 332178448 AEE14137.1 WP_013755865.1 fig|747365.3.peg.508 432 432 yes 1891998 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 528 530 yes 1891999 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28452, 1218564, 1218565 Leptospira alstoni, Leptospira alstoni serovar Pingchang str. 80-412, Leptospira alstoni serovar Sichuan str. 79601 Bacteria UP000015445, UP000011988 523636358, 529337856, 463331360 EQA81763.1, EMJ96367.1 WP_020772682.1 fig|1218565.3.peg.1222 450 505 yes 1892000 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 717608 Clostridium cf. saccharolyticum K10 Bacteria UP000008797 295090610 447 449 yes 1892001 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1165841 Sulfurovum sp. AR Bacteria UP000003180 495520572, 385343438 EIF50159.1 WP_008245217.1 fig|1165841.3.peg.1757 623 629 yes 1892002 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 174, 1049767, 1049776, 1049782, 1193009 Leptospira borgpetersenii, Leptospira borgpetersenii serovar Javanica str. UI 09931, Leptospira borgpetersenii serovar Mini str. 201000851, Leptospira borgpetersenii str. UI 09149, Leptospira borgpetersenii str. 200801926 Bacteria UP000014570, UP000017056, UP000001145, UP000002837 488825988, 514172313, 478970452, 410741197, 410362343 EPG57927.1, ENO62534.1, EKQ89955.1, EKP13383.1 WP_002738394.1 fig|1291207.3.peg.1524, fig|1291205.3.peg.5705, fig|1049767.3.peg.3126, fig|1049765.3.peg.53, fig|1193009.3.peg.2480, fig|1049776.3.peg.516, fig|1049782.3.peg.3587 511 511 yes 1892003 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263053 Bacteroides stercoris CAG:120 Environmental samples UP000018395 547516563, 524285886 WP_022103435.1 562 562 yes 1892004 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 71433, 1082933 Mesorhizobium amorphae, Mesorhizobium amorphae CCNWGS0123 Bacteria UP000002949 493217607, 355544877 EHH13948.1 WP_006199668.1 fig|1082933.3.peg.244 597 611 yes 1892005 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 674529, 1263044 Bacteroides faecis, Bacteroides faecis CAG:32 Bacteria, Environmental samples UP000017967 498224145, 524564626 WP_010538301.1 566 566 yes 1892006 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1215077 Clostridium difficile E9 Bacteria UP000018066 549358419 460 471 yes 1892007 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 354 356 no 1892008 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1338034 Vibrio parahaemolyticus, Vibrio parahaemolyticus O1:Kuk str. FDA_R31 Bacteria UP000028114, UP000014929 526241892, 523825821 AGQ89691.1 WP_020839860.1 640 646 yes 1892009 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454000 Candidatus Accumulibacter sp. SK-11 Bacteria UP000020226 736894672, 589603009 EXI74899.1 WP_034893663.1 638 638 yes 1892010 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 73141, 765911 Thiocystis violascens, Thiocystis violascens DSM 198 Bacteria UP000006062 504592625, 390428259 AFL75324.1 WP_014779727.1 627 630 yes 1892011 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1261069, 1261070 Gardnerella vaginalis JCP8481A, Gardnerella vaginalis JCP8481B Bacteria UP000014586, UP000014572 514580845, 514580436 EPI43383.1, EPI43013.1 658 875 yes 1892012 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29159 Crassostrea gigas Invertebrates UP000005408 762167162, 405945202 EKC17208.1 XP_011421903.1 614 615 yes 1892013 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 166314 Synechococcus sp. WH 8109 Bacteria UP000002780 572996305 AHF62566.1 479 486 yes 1892014 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 231053 Saccharibacter floricola Bacteria 517809293 WP_018979501.1 587 588 yes 1892015 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53335, 1408177 Pantoea agglomerans Eh318 Bacteria UP000025295 497946901, 632530828 KDA94204.1 WP_010261057.1 632 640 yes 1892016 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 702113 Novosphingobium sp. PP1Y Bacteria UP000009242 503598102, 333938408 WP_013832178.1 fig|702113.7.peg.1032 618 622 yes 1892017 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3641 Theobroma cacao Plants UP000026915 590588280, 590588276, 590588269, 590588265, 590588256, 508786530, 508786529, 508786527, 508786526, 508786525 EOY33786.1, EOY33785.1, EOY33783.1, EOY33782.1, EOY33781.1 XP_007016167.1, XP_007016166.1, XP_007016164.1, XP_007016163.1, XP_007016162.1 545 648 yes 1892018 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263077 Eubacterium eligens CAG:72 Environmental samples UP000018175 547479836, 524278016 WP_022097795.1 434 435 yes 1892019 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1240348 Salmonella enterica, Salmonella enterica subsp. houtenae serovar 16:z4,z32:-- str. RKS3027 Bacteria UP000054489, UP000013116 489044650, 481049895 ENZ84497.1 WP_002954910.1 fig|1240348.7.peg.3921 626 631 yes 1892020 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1385944 Bifidobacterium breve 31L Bacteria UP000019286 584610631 EWH39929.1 638 917 yes 1892021 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446609, 1005435 Escherichia coli, Escherichia coli O157:H7 str. 06-3745, Escherichia coli 99.1762 Bacteria UP000036210, UP000023991, UP000011517 487463609, 606915465, 444641643 EYZ48869.1, ELW14871.1 WP_001693838.1 fig|1005435.3.peg.4957 626 631 yes 1892022 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 158850, 500637 Providencia rustigianii, Providencia rustigianii DSM 4541 Bacteria UP000005512 493867048, 282567649 EFB73184.1 WP_006813670.1 628 662 yes 1892023 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 545617 Bartonella sp. AR 15-3 Bacteria 319405342 599 608 yes 1892024 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 997350 Peptoniphilus indolicus ATCC 29427 Bacteria UP000003422 348663597 EGY80159.1 fig|997350.3.peg.669 431 431 yes 1892025 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 676, 1336752 Vibrio fluvialis, Vibrio fluvialis PG41 Bacteria UP000051756, UP000014854 520912234, 519728649 EPP20027.1 WP_020331859.1 640 649 yes 1892026 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 303, 1005395 Pseudomonas putida, Pseudomonas putida CSV86 Bacteria UP000054813, UP000010448 496891302, 428762535 EKX84738.1 WP_009399511.1 fig|1005395.3.peg.2524 627 629 yes 1892027 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217708 Acinetobacter sp. NIPH 2100 Bacteria UP000013196 491433522, 480208650 ENX44385.1 WP_005291315.1 fig|1217708.3.peg.301 626 631 yes 1892028 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 4577 Zea mays Plants UP000007305 414871951 216 223 no 1892029 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1415630 Pseudomonas sp. TKP Bacteria UP000018725 568198691, 566061038 AHC33139.1 WP_024073055.1 629 634 yes 1892030 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 703, 1315976 Plesiomonas shigelloides, Plesiomonas shigelloides 302-73 Bacteria UP000014012 499149735, 499066789 EON89110.1 WP_010863039.1 fig|1315976.3.peg.1390 642 658 yes 1892031 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 72520 Nannochloropsis gaditana Plants UP000019335 585109729 EWM27469.1 548 641 yes 1892032 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1248903, 1248915 Escherichia coli, Escherichia coli O145:H28 str. RM12761, Escherichia coli O145:H28 str. RM13516 Bacteria UP000036210, UP000025234, UP000019022 644953218, 788893971, 628031298, 573937637 KJW44694.1, AHY67765.1, AHG17442.1 WP_025380651.1 626 631 yes 1892033 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46354, 697303 Thermoanaerobacter wiegelii, Thermoanaerobacter wiegelii Rt8.B1 Bacteria UP000008276 503829366, 344033694 AEM79420.1 WP_014063360.1 431 432 yes 1892034 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 758793 Burkholderia sp. RPE64 Bacteria UP000013966 511284614, 506942603 WP_016344881.1 fig|758793.3.peg.972 642 643 yes 1892035 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2745, 1204738, 1346287 Halomonas titanicae BH1, Halomonas sp. A3H3 Bacteria UP000011651, UP000018258 496588712, 445565448, 532592978 ELY21558.1 WP_009287210.1 fig|1204738.3.peg.2317 631 634 yes 1892036 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406, 1429244 Paenibacillus polymyxa, Paenibacillus polymyxa CR1 Bacteria UP000031922, UP000018661 565997375, 565990636, 565673808 AHC18378.1 WP_023987003.1, YP_008910213.1 593 614 yes 1892037 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144315 Variovorax sp. CF313 Bacteria UP000007277 495102985, 398089723 EJL80228.1 WP_007827808.1 fig|1144315.3.peg.92 624 628 yes 1892038 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1160721 Ruminococcus sp. 80/3 Bacteria UP000027600 752689275, 571259382 WP_041337142.1 437 437 yes 1892039 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1216962 Helicobacter heilmannii ASB1.4 Bacteria UP000010821 408907713 442 444 yes 1892040 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375, 1037409 Bradyrhizobium japonicum, Bradyrhizobium japonicum USDA 6 Bacteria UP000030904, UP000005663 504305798, 846671425, 736034822, 354955366 KMJ99439.1, AJA61283.1 WP_014492900.1 fig|1037409.3.peg.2793 623 632 yes 1892041 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 662755 Corynebacterium resistens DSM 45100 Bacteria UP000000492 336101488 AEI09308.1 600 621 yes 1892042 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 645463, 645462 Clostridium difficile R20291, Clostridium difficile CD196 Bacteria UP000002070, UP000015885 260211439, 260207989 fig|699034.5.peg.63, fig|645462.3.peg.60, fig|479834.4.peg.1879, fig|645463.3.peg.60, fig|479832.7.peg.496, fig|499176.4.peg.2328, fig|699033.6.peg.61, fig|479833.4.peg.482, fig|455631.3.peg.1919 244 249 no 1892043 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1192593 Salmonella enterica, Salmonella enterica subsp. enterica serovar Enteritidis str. 2010K-0286 Bacteria UP000054489, UP000015796 515148415, 514652576 EPJ10209.1 WP_016777082.1 626 631 yes 1892044 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 658659 Erysipelotrichaceae bacterium 3_1_53 Bacteria UP000006223 496572389, 308915171 EFP60945.1 WP_009273507.1 77 77 no 1892045 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1717, 698968, 698973 Corynebacterium diphtheriae, Corynebacterium diphtheriae HC02, Corynebacterium diphtheriae BH8 Bacteria UP000033584, UP000007158, UP000007866 504083373, 372109471, 371583893 AEX75531.1, AEX47558.1 WP_014317367.1 fig|698968.3.peg.31, fig|698973.3.peg.31 592 599 yes 1892046 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 517056533 WP_018245351.1 600 607 yes 1892047 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 721133, 1231190 Nitratireductor sp. C115, Nitratireductor indicus C115 Bacteria UP000007374 497055928, 407430318 EKF42992.1 WP_009449892.1 fig|1231190.3.peg.1399 597 604 yes 1892048 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 585353469 WP_024235077.1 626 631 yes 1892049 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59600, 688270 Cellulophaga algicola, Cellulophaga algicola DSM 14237 Bacteria UP000008634 503316770, 319422851 ADV49960.1 WP_013551431.1 fig|688270.3.peg.2714 619 619 yes 1892050 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 858619 Corynebacterium variabile DSM 44702 Bacteria UP000006659 340534866 AEK37346.1 550 563 yes 1892051 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294, 746360 Pseudomonas fluorescens, Pseudomonas fluorescens WH6 Bacteria UP000060991, UP000004576 489263480, 311287169 EFQ65730.1 WP_003171320.1 627 629 yes 1892052 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 471, 981331, 1217653, 575585 Acinetobacter calcoaceticus, Acinetobacter calcoaceticus DSM 30006, Acinetobacter calcoaceticus ANC 3680, Acinetobacter calcoaceticus RUH2202 Bacteria UP000032475, UP000013024, UP000013274, UP000005126 489750450, 768323371, 480062542, 480056944, 262257584, 743951326 KJH55337.1, ENW01472.1, ENV95964.1, EEY76319.1 WP_003654459.1 fig|1217653.3.peg.623, fig|981331.3.peg.345, fig|575585.3.peg.2537, fig|1221295.3.peg.1417 621 625 yes 1892053 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 421628, 1354791 Ectothiorhodospira haloalkaliphila, Halorhodospira halochloris str. A Bacteria UP000019442 644117736, 589290073 AHK78216.1 WP_025280566.1 626 629 yes 1892054 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37330, 1415166 Nocardia nova, Nocardia nova SH22a Bacteria UP000019150 644668589, 576089547 AHH21937.1 WP_025353219.1 542 543 yes 1892055 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173, 214675 Leptospira interrogans, Leptospira interrogans serovar Manilae Bacteria UP000037872, UP000036269 642963311, 605703858 EYU62218.1 WP_025176374.1 441 495 yes 1892056 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36845, 1294142 Clostridium intestinale, Clostridium intestinale URNW Bacteria UP000016721 546161057, 544193726 ERK29697.1 WP_021802925.1 437 437 yes 1892057 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 13690, 883163 Sphingobium yanoikuyae, Sphingobium yanoikuyae ATCC 51230 Bacteria UP000028534, UP000009887 490319947, 425711753 EKU74768.1 WP_004209432.1 fig|883163.3.peg.2344 624 631 yes 1892058 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1773, 1423548 Mycobacterium tuberculosis, Mycobacterium tuberculosis BTB11-299 Bacteria UP000065426, UP000025501 685954710, 626961534 KCQ84822.1 WP_031676188.1 544 547 yes 1892059 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47758 Streptomyces sulphureus Bacteria 518377580 WP_019547787.1 595 598 yes 1892060 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173951 Salmonella enterica, Salmonella enterica subsp. salamae serovar 58:l,z13,z28:z6 str. 00-0163 Bacteria UP000054489, UP000017301 554676955, 554019914 ESE66368.1 WP_023177992.1 626 631 yes 1892061 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1206724 Nocardia brasiliensis NBRC 14402 Bacteria UP000026910 635329418 536 537 yes 1892062 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 119434, 1227485 Halorubrum tebenquichense, Halorubrum tebenquichense DSM 14210 Archaea 493679886, 445683157 ELZ35560.1 WP_006630085.1 M0DJD6 M0DJD6_9EURY 450 482 yes 1892063 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1310835 Acinetobacter baumannii 24860_1 Bacteria UP000023996 611010972 EZJ15872.1 365 374 no 1892064 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1310835 Acinetobacter baumannii 24860_1 Bacteria UP000023996 611010973 EZJ15873.1 251 251 no 1892065 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 716541 Enterobacter cloacae, Enterobacter cloacae subsp. cloacae ATCC 13047 Bacteria UP000036177, UP000002363 502860036, 296100625, 685449577, 295055084 KGB10389.1, ADF59822.1 WP_013095012.1, YP_003610771.1 fig|716541.4.peg.543 626 631 yes 1892066 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1438801, 1438799, 1438700, 1328374 Klebsiella pneumoniae, Klebsiella pneumoniae MGH-80, Klebsiella pneumoniae MGH-76, Klebsiella pneumoniae BIDMC 61, Klebsiella pneumoniae MGH 40 Bacteria UP000036212, UP000027533, UP000027558, UP000027536, UP000017610 556471713, 821223999, 636420911, 636411819, 635938975, 555124425 KKY96055.1, KDL97854.1, KDL88853.1, KDH19250.1, ESM67292.1 WP_023323453.1 626 631 yes 1892067 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281270 Escherichia coli, Escherichia coli UMEA 3805-1 Bacteria UP000036210, UP000016254 545298131, 535870371 ERA02052.1 WP_021578328.1 626 631 yes 1892068 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1501, 86416 Clostridium pasteurianum, Clostridium pasteurianum BC1 Bacteria UP000013523 505430034, 488452159 AGK98861.1 WP_015617136.1 fig|86416.3.peg.4124 433 433 yes 1892069 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 766499 Citreicella sp. 357 Bacteria UP000003110 497190024, 384466827 EIE51318.1 WP_009504286.1 fig|766499.3.peg.1848 590 593 yes 1892070 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553611, 1001530 Photobacterium leiognathi, Photobacterium leiognathi subsp. mandapamensis svers.1.1. Bacteria UP000032558, UP000003966 496273977, 328489235 WP_008986015.1 637 640 yes 1892071 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 93466, 771875 Fervidobacterium pennivorans, Fervidobacterium pennivorans DSM 9078 Bacteria UP000007384 504264132, 383109167 AFG34770.1 WP_014451234.1 fig|771875.3.peg.657 427 427 yes 1892072 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 796606 Bacillus methanolicus MGA3 Bacteria UP000010309 662717617, 387588779 AIE58827.1, EIJ81100.1 589 589 yes 1892073 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265 Ruminococcus flavefaciens Bacteria 518508002 WP_019678209.1 437 437 yes 1892074 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28199, 572480 Arcobacter nitrofigilis, Arcobacter nitrofigilis DSM 7299 Bacteria UP000000939 502899082, 296095963 ADG91913.1 WP_013134058.1 fig|572480.3.peg.246 448 449 yes 1892075 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1007104 Sphingomonas sp. S17 Bacteria UP000005315 332012752 EGI54818.1 fig|1007104.3.peg.2289 601 604 yes 1892076 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1716, 1203622, 1203624 Corynebacterium sp. KPL1989, Corynebacterium sp. KPL1995 Bacteria UP000017102, UP000017162 552766416, 550777032, 550742524 ERS75081.1, ERS42073.1 WP_023018301.1 603 610 yes 1892077 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 873, 690850 Desulfovibrio africanus, Desulfovibrio africanus str. Walvis Bay Bacteria UP000007844 504024459, 332551550 EGJ48594.1 WP_014258453.1 418 424 no 1892078 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 540988 Thermus sp. PRI-3838 Bacteria 551067621 WP_022798702.1 434 435 yes 1892079 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 366649, 338, 317013, 427081 Xanthomonas fuscans subsp. fuscans, Xanthomonas axonopodis pv. phaseoli, Xanthomonas fuscans subsp. aurantifolii str. ICPB 11122 Bacteria UP000030830, UP000030394, UP000004489 549714139, 495242962, 749806442, 746952784, 712958960, 712950951, 712948943, 712947698, 712574933, 700936754, 700930879, 700926970, 700926516, 695261014, 292598593, 549145078 KIJ02026.1, KIF11428.1, KGU54353.1, KGU47040.1, KGU45103.1, KGU43905.1, KGT56175.1, KGP35139.1, KGP29788.1, KGP26071.1, KGP25638.1, KGK67641.1, EFF42742.1 YP_008638002.1, WP_007967725.1 624 625 yes 1892080 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 263908, 1077974 Gordonia effusa, Gordonia effusa NBRC 100432 Bacteria UP000035034 494527508, 359311452 WP_007316960.1 fig|1077974.3.peg.1170 545 555 yes 1892081 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 535744, 1074000 Cronobacter genomosp. 1, Cronobacter sp. NCTC 9529 Bacteria UP000009354 494978706, 426508992 WP_007704730.1 626 633 yes 1892082 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 232348 Synechococcus sp. CB0101 Bacteria 497998200 WP_010312356.1 457 459 yes 1892083 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 1204474, 693991, 457405 Fusobacterium nucleatum, Fusobacterium nucleatum CTI-1, Fusobacterium nucleatum subsp. polymorphum F0401, Fusobacterium sp. 7_1 Bacteria UP000017136, UP000004941, UP000002799 495978220, 551108711, 511334327, 229433551 ERT39806.1, EHG19445.2, EEO43763.1 WP_008702799.1 fig|457405.10.peg.2366 433 433 yes 1892084 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 702976 Salmonella enterica, Salmonella enterica subsp. enterica serovar Enteritidis str. 22704 Bacteria UP000054489, UP000010970 487480383, 434968058 ELL60817.1 WP_001698400.1 fig|702976.3.peg.2393 626 631 yes 1892085 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 378211, 1000565 Methyloversatilis universalis, Methyloversatilis universalis FAM5 Bacteria UP000005019 495338341, 333442789 EGK70755.1 WP_008063077.1 638 638 yes 1892086 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630, 1329363, 1329364, 1329366, 1329365, 1071969, 1243181, 930944 Yersinia enterocolitica, Yersinia enterocolitica subsp. palearctica YE-P1, Yersinia enterocolitica subsp. palearctica YE-P4, Yersinia enterocolitica subsp. palearctica YE-150, Yersinia enterocolitica subsp. palearctica YE-149, Yersinia enterocolitica subsp. palearctica PhRBD_Ye1, Yersinia enterocolitica IP 10393, Yersinia enterocolitica subsp. palearctica Y11 Bacteria UP000029427, UP000014192, UP000014202, UP000014131, UP000014178, UP000004204, UP000010697, UP000008084 491308094, 507504460, 507503831, 507503813, 507496699, 351776935, 812059499, 803138142, 802272711, 431789866, 318607530 EOR74092.1, EOR73480.1, EOR73463.1, EOR66529.1, EHB19199.1 WP_005166085.1 fig|1329363.3.peg.3478, fig|1329366.3.peg.3490, fig|930944.6.peg.3485, fig|940288.3.peg.4164, fig|940287.3.peg.269, fig|1071969.3.peg.3958, fig|1329365.3.peg.3482, fig|1243181.3.peg.1450, fig|1329364.3.peg.3467 634 655 yes 1892087 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 257003 Sphingomonas phyllosphaerae Bacteria 550936340 WP_022684745.1 607 615 yes 1892088 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 29546, 1234378, 363253 Lawsonia intracellularis, Lawsonia intracellularis N343, Lawsonia intracellularis PHE/MN1-00 Bacteria UP000011822, UP000002430 499846286, 441493670, 94731628 AGC50364.1 WP_011527020.1 fig|1234378.3.peg.1015, fig|363253.4.peg.1016 419 425 no 1892089 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 264574 Oceanimonas smirnovii Bacteria 518777326 WP_019934615.1 642 651 yes 1892090 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 401473 Bifidobacterium dentium Bd1 Bacteria UP000008693 283103086 ADB10192.1 fig|401473.3.peg.1516, fig|473819.7.peg.1347 582 836 yes 1892091 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1187065 Mycobacterium sp. 012931 Bacteria UP000014966 521717417 EPQ49561.1 475 511 yes 1892092 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 688 Aliivibrio logei Bacteria 515590263 WP_017022923.1 640 648 yes 1892093 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 881, 882, 573059, 391774 Desulfovibrio vulgaris, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris RCH1, Desulfovibrio vulgaris DP4 Bacteria UP000002194, UP000001496, UP000009173 499241164, 46579822, 311234171, 120562936, 46449237 ADP87025.1, ABM28680.1, AAS95889.1 WP_010938704.1, YP_010630.1 206854 fig|391774.5.peg.1666, fig|882.1.peg.1405, fig|573059.3.peg.1174 419 429 no 1892094 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 434085 gamma proteobacterium IMCC2047 Bacteria UP000004485 330720236 EGG98606.1 fig|434085.3.peg.1817 371 372 yes 1892095 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47917, 1332070 Serratia fonticola, Serratia fonticola AU-P3(3) Bacteria UP000061771, UP000016623 544755282, 544006674 ERK05513.1 WP_021182167.1 633 647 yes 1892096 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263089 Odoribacter laneus CAG:561 Environmental samples UP000017974 547316288, 524213816 WP_022047815.1 583 584 yes 1892097 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116132 Escherichia coli, Escherichia coli MP021552.7 Bacteria UP000036210, UP000012303 487412330, 476031521 EMU57201.1 WP_001679974.1 fig|1116132.3.peg.5087 626 631 yes 1892098 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 821, 1235786 Bacteroides vulgatus, Bacteroides vulgatus dnLKV7 Bacteria UP000061587, UP000014151 511017587, 507737829 EOR96968.1 WP_016271936.1 fig|1235786.3.peg.4451 566 566 yes 1892099 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1348334 Lyngbya aestuarii BL J Bacteria UP000017127 550817700 ERT09088.1 443 443 yes 1892100 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286 517758323 WP_018928531.1 628 629 yes 1892101 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204, 1244083 Campylobacter showae, Campylobacter showae CSUNSWCD Bacteria UP000011939 497163481, 421960916 EKU12518.1 WP_009492964.1 fig|1244083.3.peg.464 442 443 yes 1892102 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262925 Prevotella sp. CAG:386 Environmental samples UP000018046 547844187, 524482759 WP_022251641.1 529 529 yes 1892103 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 516397968 WP_017787366.1 645 663 yes 1892104 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 93944 Nonomuraea sp. ATCC 39727 Bacteria 32487271 507 514 yes 1892105 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 884215, 871271 Candidatus Zinderia insecticola, Candidatus Zinderia insecticola CARI Bacteria UP000001303 503080480, 306482926 ADM89797.1 WP_013315374.1 307 483 no 1892106 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33995 Gluconacetobacter europaeus Bacteria UP000037566 517915479 WP_019085687.1 605 613 yes 1892107 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1190577, 996307 Neisseria meningitidis, Neisseria meningitidis NM0552, Neisseria meningitidis alpha522 Bacteria UP000050419, UP000015889 545067546, 530912968, 389606787 EQD10881.1 WP_021439171.1 625 633 yes 1892108 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 602 602 yes 1892109 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 348043, 1214101 Streptomyces davawensis, Streptomyces davawensis JCM 4913 Bacteria UP000008043 505472594, 408530780 WP_015659299.1 593 595 yes 1892110 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 649189 Streptomyces sp. ACT-1 Bacteria 490065636, 326658435 EGE43281.1 WP_003967839.1 583 606 yes 1892111 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 252966, 697281 Mahella australiensis, Mahella australiensis 50-1 BON Bacteria UP000008457 503547574, 332700281 AEE97222.1 WP_013781650.1 fig|697281.3.peg.2088 426 426 yes 1892112 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1174528 Fischerella sp. PCC 9339 Bacteria 515879348 WP_017309931.1 459 460 yes 1892113 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 86182 Curvibacter lanceolatus Bacteria 518403884 WP_019574091.1 616 621 yes 1892114 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626 631 yes 1892115 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54299, 251229 Chroococcidiopsis thermalis, Chroococcidiopsis thermalis PCC 7203 Bacteria UP000010384 504967526, 428009518 AFY88081.1 WP_015154628.1 fig|251229.3.peg.3053 455 456 yes 1892116 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1174684 Sphingopyxis sp. MC1 Bacteria UP000013072 489131232, 480612413 ENY82022.1 WP_003041019.1 fig|1174684.3.peg.805 621 628 yes 1892117 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262832 Clostridium sp. CAG:7 Environmental samples UP000018268 546486326, 524062391 WP_021871227.1 434 435 yes 1892118 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 412449 Leptospirillum ferrodiazotrophum Bacteria UP000009374 251772627 EES53192.1 451 454 yes 1892119 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262802 Clostridium sp. CAG:411 Environmental samples UP000018022 548221287, 524741853 WP_022440399.1 433 434 yes 1892120 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1391912, 1217688, 520708, 903915, 436717 Acinetobacter oleivorans CIP 110421, Acinetobacter sp. NIPH 542, Acinetobacter sp. NIPH 817, Acinetobacter baumannii WC-141, Acinetobacter sp. DR1 Bacteria UP000017334, UP000013138, UP000013056, UP000009393, UP000000392 490933281, 554738621, 480211216, 479956390, 422942563, 298701948 ESK43742.1, ENX46915.1, ENV01595.1, EKU37610.1, ADI92513.1 WP_004795134.1 fig|1217688.3.peg.748, fig|520708.3.peg.3484, fig|436717.3.peg.3605, fig|903915.3.peg.2843 621 625 yes 1892121 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 480, 749219, 857571, 857573, 857575, 857574, 857577, 857581, 857578, 1236608 Moraxella catarrhalis, Moraxella catarrhalis RH4, Moraxella catarrhalis O35E, Moraxella catarrhalis B507, Moraxella catarrhalis B502, Moraxella catarrhalis B503, Moraxella catarrhalis 12P80B1, Moraxella catarrhalis 7169, Moraxella catarrhalis 46P47B1, Moraxella catarrhalis BBH18 Bacteria UP000058148, UP000023784, UP000023780, UP000023782, UP000023783, UP000023793, UP000023797, UP000023789, UP000000930 489760198, 407813839, 326578072, 326574372, 326571833, 326571714, 326563082, 326561754, 326560712, 295919938 EKF84618.1, EGE27932.1, EGE24315.1, EGE21839.1, EGE21727.1, EGE13355.1, EGE12089.1, EGE11080.1, ADG60289.1 WP_003664145.1 fig|857578.3.peg.1471, fig|857575.3.peg.370, fig|857574.3.peg.440, fig|749219.3.peg.15, fig|857577.3.peg.1898, fig|857573.3.peg.1173, fig|857581.3.peg.313, fig|857571.5.peg.15 618 623 yes 1892122 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33046, 1094560 Bartonella taylorii, Bartonella taylorii 8TBB Bacteria UP000002648 490998644, 395428267 EJF94349.1 WP_004860367.1 fig|1094560.3.peg.1376 602 611 yes 1892123 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29498, 1051646, 866909 Vibrio tubiashii, Vibrio tubiashii ATCC 19109, Vibrio tubiashii NCIMB 1337 Bacteria UP000030463, UP000003836, UP000004438 490883374, 703563079, 384573787, 342819528 AIW15462.1, EIF04275.1, EGU54371.1 WP_004745347.1 fig|866909.3.peg.1876, fig|1051646.3.peg.2500 640 646 yes 1892124 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29303, 1003195 Streptomyces cattleya, Streptomyces cattleya NRRL 8057 Bacteria UP000006623 503909918, 365807329, 337767173 AEW95545.1 WP_014143912.1 fig|1126229.3.peg.2976 588 594 yes 1892125 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 511, 1156918 Alcaligenes faecalis, Alcaligenes faecalis subsp. faecalis NCIB 8687 Bacteria UP000068452, UP000004331 489898478, 393162832 EJC62887.1 WP_003801919.1 fig|1156918.4.peg.1492 637 638 yes 1892126 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53412, 1245471 Pseudomonas resinovorans, Pseudomonas resinovorans NBRC 106553 Bacteria UP000015503 512737257, 512379478 WP_016495069.1 fig|1245471.3.peg.5289 627 627 yes 1892127 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29497 Vibrio splendidus Bacteria UP000050463 515643294 WP_017075894.1 640 649 yes 1892128 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 544911 Massilia niastensis Bacteria 522145623 WP_020656831.1 635 637 yes 1892129 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 948, 1184254 Anaplasma phagocytophilum, Anaplasma phagocytophilum Dog2 Bacteria UP000033356, UP000024386 526476598, 526278964 AGR81360.1 WP_020849583.1 557 557 yes 1892130 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1307834 Gluconobacter frateurii NBRC 103465 Bacteria UP000053931 531093344 605 617 yes 1892131 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33047, 1094561 Bartonella vinsonii, Bartonella vinsonii subsp. arupensis Pm136co Bacteria UP000008948 491003807, 395432738 EJF98713.1 WP_004865528.1 fig|1094561.3.peg.306 602 611 yes 1892132 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 844, 273121 Wolinella succinogenes, Wolinella succinogenes DSM 1740 Bacteria UP000000422 499452266, 47606100, 34483951 WP_011139730.1 Q7M818 THIC_WOLSU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 580084 fig|273121.1.peg.1774 448 449 yes 1892133 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase ISS 1114 phosphomethylpyrimidine synthase (ThiC) 891, 281689 Desulfuromonas acetoxidans, Desulfuromonas acetoxidans DSM 684 Bacteria UP000005695 492846264, 95134121 EAT15779.1 WP_006000218.1 fig|281689.4.peg.1783, fig|891.1.peg.2189 434 435 no 1892134 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2285, 1028567, 1028566, 330779 Sulfolobus acidocaldarius, Sulfolobus acidocaldarius Ron12/I, Sulfolobus acidocaldarius N8, Sulfolobus acidocaldarius DSM 639 Archaea UP000065473, UP000011280, UP000011281, UP000001018 499596327, 449036961, 449034685, 68566631, 76363447 AGE72386.1, AGE70111.1, AAY79560.1 WP_011277061.1 Q4JCB9, A0A0U2Y1Q4, M1IZB0, M1ISC1 THIC_SULAC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} A0A0U2Y1Q4_9CREN, M1IZB0_9CREN, M1ISC1_9CREN 930263 fig|330779.3.peg.242 427 428 yes 1892135 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 779, 302409 Ehrlichia ruminantium, Ehrlichia ruminantium str. Gardel Bacteria UP000000533 499574671, 75432802, 58416636 WP_011255454.1 Q5FHG9 THIC_EHRRG Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 847015 fig|302409.3.peg.461 555 555 yes 1892136 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83816, 634498 Methanobrevibacter ruminantium, Methanobrevibacter ruminantium M1 Archaea UP000008680 502720071, 288559505, 288542215 ADC46099.1 WP_012955055.1, YP_003422991.1 D3DZE4 D3DZE4_METRM 10381246 432 432 yes 1892137 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1089444, 1231725 Dickeya solani, Dickeya sp. D s0432-1 Bacteria UP000031016, UP000017142 550643844, 549992130 ERO59281.1 WP_022631768.1 631 655 yes 1892138 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 221360 Synechococcus sp. RS9917 Bacteria UP000005593 494161260, 86168928 EAQ70184.1 WP_007100996.1 fig|221360.3.peg.1096 464 466 yes 1892139 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1224136 Enterobacteriaceae bacterium LSJC7 Bacteria 515944940 WP_017375523.1 626 642 yes 1892140 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|940296.3.peg.2183 624 671 yes 1892141 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1262850 Collinsella sp. CAG:166 Environmental samples UP000018358 547476278, 524274196 WP_022094508.1 108 109 no 1892142 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1088740, 1001994 Candidatus Nitrosoarchaeum koreensis, Candidatus Nitrosoarchaeum koreensis MY1 Archaea 494814604, 339519575 EGP93298.1 WP_007550012.1 F9CVJ6 F9CVJ6_9ARCH 439 439 yes 1892143 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 542, 264203 Zymomonas mobilis, Zymomonas mobilis subsp. mobilis ZM4 Bacteria UP000001173 499559344, 56542642, 81598350 AAV88796.1 WP_011240127.1 Q5NR58 THIC_ZYMMO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 956945, 7709606 fig|1231376.3.peg.1838, fig|264203.3.peg.668 602 604 yes 1892144 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1333523 Salinarchaeum sp. Harcht-Bsk1 Archaea UP000014072 521282030, 510881534, 507915806 AGN01404.1 WP_020446298.1, YP_008054202.1 R4W9D4 R4W9D4_9EURY 457 483 yes 1892145 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354276, 61645, 1400154 Enterobacter asburiae, Enterobacter cloacae UCI 49 Bacteria UP000036088, UP000020987 697054381, 829242070, 822839331, 578171306 KLP46972.1, KLF97433.1, EUL31658.1 WP_033146986.1 626 631 yes 1892146 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 118323, 56110 Oscillatoria acuminata, Oscillatoria acuminata PCC 6304 Bacteria UP000010367 504961549, 428001166 AFY82009.1 WP_015148651.1 fig|56110.3.peg.2834 456 457 yes 1892147 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 138074, 914128 Serratia symbiotica, Serratia symbiotica str. Tucson Bacteria UP000042738, UP000013568 493760200, 320030205 EFW12221.1 WP_006708926.1 633 647 yes 1892148 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1134474 Cellvibrio sp. BR Bacteria UP000003395 494917029, 387938383 EIK44936.1 WP_007643067.1 fig|1134474.3.peg.2500 641 642 yes 1892149 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1248732, 1145176, 1145168 Neisseria meningitidis, Neisseria meningitidis 992008, Neisseria meningitidis 2007461, Neisseria meningitidis 2004032 Bacteria UP000050419, UP000027902, UP000014596, UP000013382 488187544, 663090434, 514068120, 485371695 KER38732.1, EPF53141.1, EOC31565.1 WP_002258752.1 fig|1145176.3.peg.2529, fig|1145168.3.peg.2521 625 633 yes 1892150 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1118054 Brevibacillus sp. phR Bacteria 517951508 WP_019121716.1 567 567 yes 1892151 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1190572 Neisseria meningitidis, Neisseria meningitidis NM3139 Bacteria UP000050419, UP000015777 545065551, 530907845 EQD06066.1 WP_021437935.1 625 633 yes 1892152 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554 555 yes 1892153 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56877, 1002805 Helicobacter bizzozeronii, Helicobacter bizzozeronii CCUG 35545 Bacteria UP000004083 492874190, 375315331 WP_006018382.1 fig|1002805.5.peg.2206 445 446 yes 1892154 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 313628 Lentisphaera araneosa HTCC2155 Bacteria UP000004947 149136247 EDM24703.1 157 157 no 1892155 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 195522 Thermococcus nautilus Archaea UP000019434 757135352, 589909088 AHL22137.1 WP_042689602.1 W8NSP1 W8NSP1_9EURY 426 426 yes 1892156 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 937450 Oxalobacteraceae bacterium IMCC9480 Bacteria UP000004494 327548317 EGF33006.1 638 646 yes 1892157 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1685, 1385941 Bifidobacterium breve, Bifidobacterium breve NCFB 2258 Bacteria UP000029049, UP000019334 643833104, 585133011 AHJ21481.1 WP_025263093.1 637 917 yes 1892158 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 490, 1095748 Neisseria sicca, Neisseria sicca VK64 Bacteria UP000004473 489860396, 385699572 EIG29862.1 WP_003764036.1 fig|1095748.3.peg.563 625 633 yes 1892159 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 648999 Micromonospora sp. L5 Bacteria UP000008685 315408008 ADU06125.1 fig|648999.3.peg.3312 530 530 yes 1892160 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 330214 Candidatus Nitrospira defluvii Bacteria UP000001660 300604491 fig|330214.5.peg.1012 633 638 yes 1892161 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 91359 Enterovibrio calviensis Bacteria 515575538 WP_017008311.1 637 637 yes 1892162 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2251, 1227462, 1227463, 1227464 Haloferax sp. ATCC BAA-644, Haloferax sp. ATCC BAA-645, Haloferax sp. ATCC BAA-646 Archaea UP000011507, UP000011677 495850673, 445716569, 445715989, 445704067 ELZ68311.1, ELZ67741.1, ELZ55986.1 WP_008575252.1 M0G617, M0F7J9, M0G7P8 M0G617_9EURY, M0F7J9_9EURY, M0G7P8_9EURY 434 465 yes 1892163 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3641 Theobroma cacao Plants UP000026915 590588272, 508786528 EOY33784.1 XP_007016165.1 545 650 yes 1892164 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 818, 1235785 Bacteroides thetaiotaomicron, Bacteroides thetaiotaomicron dnLKV9 Bacteria UP000066931, UP000014207 511012981, 507743693 EOS02782.1 WP_016267379.1 fig|1235785.3.peg.839 565 565 yes 1892165 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 392736 Uliginosibacterium gangwonense Bacteria 517433410 WP_018604335.1 637 637 yes 1892166 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324 Stenotrophomonas maltophilia Bacteria UP000034806 515924527 WP_017355110.1 621 625 yes 1892167 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 573, 1284812 Klebsiella pneumoniae, Klebsiella pneumoniae UHKPC81 Bacteria UP000036212, UP000014314 523670880, 509602361 EOY87203.1 WP_020801588.1 fig|1284812.3.peg.423 626 631 yes 1892168 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1118154 Brevibacillus laterosporus GI-9 Bacteria UP000004427 372458941 fig|1118154.3.peg.1303 575 575 yes 1892169 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29497, 1051645 Vibrio splendidus, Vibrio splendidus ATCC 33789 Bacteria UP000050463, UP000003507 490879229, 342805479 EGU40742.1 WP_004741222.1 fig|1051645.3.peg.3384 640 649 yes 1892170 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1151308 Clostridium difficile 655 Bacteria UP000015794 531293384 EQF89128.1 278 278 no 1892171 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37372, 613026 Helicobacter bilis, Helicobacter bilis ATCC 43879 Bacteria UP000029870, UP000005085 491361727, 229374310 EEO24701.1 WP_005219645.1 fig|613026.4.peg.1790 452 453 yes 1892172 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 80867, 643561 Acidovorax avenae, Acidovorax avenae subsp. avenae ATCC 19860 Bacteria UP000002482 503358573, 323372414 ADX44683.1 WP_013593234.1 fig|643561.3.peg.3701 610 613 yes 1892173 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 167642, 572544 Ilyobacter polytropus, Ilyobacter polytropus DSM 2926 Bacteria UP000006875 503152968, 309748300 ADO82962.1 WP_013387629.1 fig|572544.3.peg.1218 426 426 yes 1892174 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 591157 Streptomyces sp. SPB78 Bacteria UP000005781 496358125, 302429362 EFL01178.1 WP_009067301.1 598 600 yes 1892175 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358220 Acidovorax sp. KKS102 Bacteria UP000006306 504825462, 407895273 AFU44482.1 WP_015012564.1 fig|358220.3.peg.774 627 634 yes 1892176 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 477693, 490899 Desulfurococcus kamchatkensis, Desulfurococcus kamchatkensis 1221n Archaea UP000006903 501636564, 218765052 ACL10451.1 WP_012607793.1 B8D338 B8D338_DESK1 fig|490899.4.peg.125 419 428 yes 1892177 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2358, 706587 Desulfomonile tiedjei, Desulfomonile tiedjei DSM 6799 Bacteria UP000006055 504621536, 390622275 AFM23482.1 WP_014808638.1 fig|706587.4.peg.855 409 411 yes 1892178 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 108980 Acinetobacter ursingii Bacteria 498274643 WP_010588799.1 627 638 yes 1892179 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1249480 uncultured Sulfuricurvum sp. RIFRC-1 Environmental samples UP000000224 505466213, 410995500 AFV96965.1 WP_015653089.1 fig|1249480.3.peg.658 456 458 yes 1892180 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 154, 869211 Spirochaeta thermophila, Spirochaeta thermophila DSM 6578 Bacteria UP000007254 504436722, 339410853 AEJ60418.1 WP_014623824.1 423 424 yes 1892181 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1299332 Mycobacterium ulcerans str. Harvey Bacteria UP000020681 576494315 EUA87742.1 382 383 yes 1892182 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46680 Pseudomonas nitroreducens Bacteria 516089846 WP_017520426.1 626 626 yes 1892183 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 530 530 yes 1892184 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28449, 546268 Neisseria subflava, Neisseria subflava NJ9703 Bacteria UP000004621 490654122, 284798021 EFC53368.1 WP_004519113.1 625 629 yes 1892185 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 203192, 1263865 Pseudomonas chloritidismutans, Pseudomonas chloritidismutans AW-1 Bacteria UP000017822 557814265, 557365695 ESQ99776.1 WP_023444878.1 626 626 yes 1892186 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1179778 Pseudomonas sp. M47T1 Bacteria UP000004339 495643618, 388277392 EIK96967.1 WP_008368197.1 fig|1179778.3.peg.1980 628 629 yes 1892187 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 515978262 WP_017408845.1 645 663 yes 1892188 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 593 596 yes 1892189 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 196024 Aeromonas hydrophila subsp. dhakensis Bacteria 498321185 WP_010635341.1 662 680 yes 1892190 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 636 647 yes 1892191 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 194, 1365662, 1183378, 1412897, 887312, 887308, 887285, 887307, 887284, 887298, 887296, 887297, 887283, 887295, 887293, 887291, 887287, 887286, 887280, 864566 Campylobacter jejuni K5, Campylobacter coli RM1875, Campylobacter coli K7, Campylobacter coli H56, Campylobacter coli LMG 9860, Campylobacter coli 151-9, Campylobacter coli LMG 9853, Campylobacter coli 67-8, Campylobacter coli 1961, Campylobacter coli 1948, Campylobacter coli 1957, Campylobacter coli 59-2, Campylobacter coli 1909, Campylobacter coli 1417, Campylobacter coli 1098, Campylobacter coli 84-2, Campylobacter coli 90-3, Campylobacter coli 111-3, Campylobacter coli JV20 Bacteria UP000024868, UP000019425, UP000018549, UP000005579, UP000005145, UP000003576, UP000005682, UP000004388, UP000004624, UP000005026, UP000005412, UP000004955, UP000005340, UP000005186, UP000004294, UP000005201, UP000005502, UP000005941, UP000003521 488868527, 631621649, 589297652, 564607614, 380592880, 380586803, 380581277, 380579171, 380565341, 380561979, 380559249, 380557591, 380556398, 380554441, 380548442, 380543195, 380533993, 380518302, 380518152, 304443709 KDA37175.1, AHK73798.1, ETC96676.1, EIB13732.1, EIB08076.1, EIB03004.1, EIB00976.1, EIA88087.1, EIA84876.1, EIA82411.1, EIA80798.1, EIA79649.1, EIA77903.1, EIA72347.1, EIA67414.1, EIA58843.1, EIA44400.1, EIA44251.1, EFM36366.1 WP_002780766.1 fig|887284.3.peg.866, fig|887291.3.peg.467, fig|887295.3.peg.167, fig|887285.3.peg.341, fig|887296.3.peg.50, fig|887286.3.peg.644, fig|887283.3.peg.1164, fig|887293.3.peg.16, fig|887307.3.peg.1039, fig|887297.3.peg.1462, fig|864566.3.peg.1381, fig|887287.3.peg.1500, fig|887298.3.peg.1352, fig|887280.3.peg.602, fig|887312.3.peg.682, fig|887308.3.peg.986 429 430 yes 1892192 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29494, 675811 Vibrio furnissii, Vibrio furnissii CIP 102972 Bacteria UP000051221, UP000005296 490862242, 260617387 EEX42570.1 WP_004724281.1 640 649 yes 1892193 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40519, 411473 Ruminococcus callidus, Ruminococcus callidus ATCC 27760 Bacteria UP000016662 545444982, 543994143 ERJ96946.1 WP_021682153.1 437 438 yes 1892194 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 45667, 195088, 240302, 156205 Halobacillus karajensis, Halobacillus dabanensis, Halobacillus trueperi Bacteria UP000028868, UP000028877, UP000028874 737535690, 662981991, 635348398, 635342029 WP_035509415.1 593 594 yes 1892195 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1155718 Streptomyces sp. MspMP-M5 Bacteria 517367564 WP_018542627.1 592 596 yes 1892196 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1217639 Acinetobacter baumannii, Acinetobacter baumannii NIPH 146 Bacteria UP000028632, UP000013052 490873778, 821296988, 479918663 KKZ34976.1, ENU66844.1 WP_004735779.1 fig|1217639.3.peg.770 641 645 yes 1892197 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1121927 Gordonia hirsuta DSM 44140 = NBRC 16056 Bacteria UP000053405 441455785 fig|1121927.3.peg.1190 533 538 yes 1892198 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 345341 Kutzneria sp. 744 Bacteria UP000030658 760036729, 585092430 EWM14371.1 WP_043719705.1 551 554 yes 1892199 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 169176, 1219035 Novosphingobium tardaugens, Novosphingobium tardaugens NBRC 16725 Bacteria UP000016568 545454446, 540736826 WP_021691439.1 617 624 yes 1892200 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 717610 498130456 WP_010444612.1 640 646 yes 1892201 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 95619 Pseudomonas sp. M1 Bacteria UP000019152 497299317, 568071940 ETM64793.1 WP_009613534.1 626 626 yes 1892202 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29497 Vibrio splendidus Bacteria UP000050463 515662857 WP_017095457.1 640 649 yes 1892203 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 341694, 596315 Peptostreptococcus stomatis, Peptostreptococcus stomatis DSM 17678 Bacteria UP000003244 495063430, 306493300 EFM65288.1 WP_007788260.1 434 434 yes 1892204 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59753, 1397526 Alcanivorax sp. PN-3 Bacteria UP000017088 552532480, 550685947 ERS10185.1 WP_022997203.1 623 625 yes 1892205 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1393669 uncultured bacterium Contigcl_289 Environmental samples 571052133 AHF25804.1 427 428 yes 1892206 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1507807, 1400346, 1144673, 1144662, 1144665, 1217668, 1217669, 1144674, 575588 Acinetobacter sp. MII, Acinetobacter lwoffii NIPH 512, Acinetobacter sp. CIP 64.7, Acinetobacter sp. CIP 101966, Acinetobacter sp. CIP 102136, Acinetobacter lwoffii NIPH 478, Acinetobacter lwoffii NIPH 715, Acinetobacter sp. CIP A162, Acinetobacter lwoffii SH145 Bacteria UP000029704, UP000013258, UP000013059, UP000013199, UP000018416, UP000018422, UP000018457, UP000018425 490407560, 692537863, 554687628, 480196703, 480189983, 480188819, 480089726, 479912867, 479865825, 262308036 KGH51228.1, ESJ94707.1, ENX32690.1, ENX26151.1, ENX25064.1, ENW28055.1, ENU61500.1, ENU17725.1, EEY89173.1 WP_004281076.1 fig|1144673.3.peg.237, fig|1217668.3.peg.2764, fig|1144662.3.peg.2860, fig|1217669.3.peg.2689, fig|1221307.3.peg.3319, fig|981327.3.peg.1614, fig|1144674.3.peg.180, fig|1144665.3.peg.396, fig|575588.3.peg.2135 627 631 yes 1892207 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217703 Acinetobacter sp. ANC 4105 Bacteria UP000013261 491333871, 480154336 ENW91260.1 WP_005191831.1 fig|1217703.3.peg.3244 626 631 yes 1892208 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 698955 Gardnerella vaginalis 55152 Bacteria UP000005936 388057326 EIK80158.1 fig|698955.3.peg.690 609 881 yes 1892209 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1496, 1151292 Clostridium difficile, Clostridium difficile CD160 Bacteria UP000058232, UP000015838 544986358, 531224228 EQF25054.1 WP_021384490.1 433 433 yes 1892210 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1297742 Myxococcus sp. (contaminant ex DSM 436) Bacteria UP000009026 488714655, 544274802 ERK92396.1 WP_002638531.1 623 627 yes 1892211 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294 Pseudomonas fluorescens Bacteria UP000060991 516095869 WP_017526449.1 628 629 yes 1892212 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 1409787 Klebsiella oxytoca, Klebsiella oxytoca G54 Bacteria UP000030350, UP000020179 695815421, 601460617 EYT02895.1 WP_032729273.1 626 631 yes 1892213 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 188144 Enterovibrio norvegicus Bacteria 515526266 WP_016959518.1 637 637 yes 1892214 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 645, 1324960 Aeromonas salmonicida, Aeromonas salmonicida subsp. pectinolytica 34mel Bacteria UP000052231, UP000015657 544710836, 530711751 EQC02448.1 WP_021141062.1 644 668 yes 1892215 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 827, 883165 Bacteroides ureolyticus, Staphylococcus pasteuri ACS-301-V-Sch3b Bacteria UP000014539 514958819, 514211784 EPH07515.1 WP_016647414.1 fig|883165.3.peg.1578 434 435 yes 1892216 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 981222 Candidatus Chloracidobacterium thermophilum B Bacteria UP000006791 347586736 AEP11266.1 fig|981222.3.peg.501 436 442 yes 1892217 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 202955, 1120928 Acinetobacter tjernbergiae, Acinetobacter tjernbergiae DSM 14971 = CIP 107465 Bacteria UP000017404 517508949, 554750961 ESK55861.1 WP_018679157.1 626 631 yes 1892218 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1036672 Tetrathiobacter kashmirensis WT001 Bacteria UP000005267 388536486 AFK61674.1 525 526 yes 1892219 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 861, 469617 Fusobacterium ulcerans, Fusobacterium ulcerans ATCC 49185 Bacteria UP000017807 492823899, 404288810 EFS26480.2 WP_005977854.1 425 425 yes 1892220 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263040 Bacteroides coprocola CAG:162 Environmental samples UP000018362 547666190, 524312499 WP_022124996.1 564 564 yes 1892221 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1387231 Pseudomonas sp. CMAA1215 Bacteria UP000017150 550109826 ERO63362.1 628 629 yes 1892222 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2223, 990316 Methanosaeta concilii, Methanosaeta concilii GP6 Archaea UP000007807 503484282, 328928092 AEB67894.1 WP_013718943.1 F4C003 F4C003_METCG 420 427 yes 1892223 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1238214, 1238198 Vibrio parahaemolyticus, Vibrio parahaemolyticus EKP-008, Vibrio parahaemolyticus 3259 Bacteria UP000028114, UP000018830, UP000015836 545084479, 567323764, 532415673 ETJ84929.1, EQM14791.1 WP_021454384.1 640 646 yes 1892224 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2176, 547558 Methanohalophilus mahii, Methanohalophilus mahii DSM 5219 Archaea UP000001059 502803276, 294496462, 292667461 ADE37310.1 WP_013038252.1, YP_003542955.1 D5E822 D5E822_METMS 10321431 427 427 yes 1892225 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 1085388 Bacillus cereus, Bacillus cereus BAG3O-1 Bacteria UP000036076, UP000013983 507065235, 500556778 EOQ20847.1 WP_016136043.1 fig|1085388.3.peg.5736 586 586 yes 1892226 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 517767287 WP_018937495.1 627 629 yes 1892227 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1563, 768706 Desulfosporosinus orientis, Desulfosporosinus orientis DSM 765 Bacteria UP000006346 503950731, 357213298 AET67916.1 WP_014184725.1 fig|768706.3.peg.2334 433 434 yes 1892228 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 72556, 1156919 Achromobacter piechaudii, Achromobacter piechaudii HLE Bacteria UP000036804, UP000006603 493261674, 400197939 EJO30902.1 WP_006224665.1 fig|1156919.3.peg.2704 636 637 yes 1892229 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1029984 Salmonella enterica, Salmonella enterica subsp. enterica serovar Enteritidis str. SARB17 Bacteria UP000054489, UP000010904 487594738, 435301261 ELO77299.1 WP_001728150.1 fig|1029984.3.peg.2642 626 631 yes 1892230 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1111454 Megasphaera sp. BV3C16-1 Bacteria UP000017090 553309021, 551686670 ERT58360.1 WP_023054080.1 433 433 yes 1892231 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29488, 243265 Photorhabdus luminescens, Photorhabdus luminescens subsp. laumondii TTO1 Bacteria UP000029997, UP000002514 499457407, 47606107, 36783919 WP_011144871.1 Q7N963 THIC_PHOLL Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 547921 fig|243265.1.peg.463 619 645 yes 1892232 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262937 Prevotella sp. CAG:891 Environmental samples UP000018147 548263906, 524789932 WP_022480929.1 440 440 yes 1892233 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 517710728 WP_018880936.1 627 629 yes 1892234 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35814, 1172205, 1331209, 1458267, 1331211, 1331210, 1331207, 1331208, 1331206, 1331251, 1331205, 1331212, 1247649, 1247648, 1247644, 1247647, 1247645, 1247646, 1281885, 1266729 Bordetella holmesii, Bordetella holmesii 44057, Bordetella bronchiseptica CDC-H643-BH, Bordetella bronchiseptica 04P3421, Bordetella bronchiseptica CDC-H785-BH, Bordetella bronchiseptica CDC-H719-BH, Bordetella bronchiseptica CDC-H629-BH, Bordetella bronchiseptica CDC-H635-BH, Bordetella bronchiseptica CDC-H585-BH, Bordetella bronchiseptica H680, Bordetella bronchiseptica CDC-H572-BH, Bordetella bronchiseptica CDC-H809-BH, Bordetella holmesii ATCC 51541, Bordetella holmesii 1058, Bordetella holmesii 30539, Bordetella holmesii 70147, Bordetella holmesii 35009, Bordetella holmesii 41130, Bordetella holmesii H558, Bordetella holmesii F627 Bacteria UP000029821, UP000026287, UP000026795, UP000026592, UP000026079, UP000026109, UP000026126, UP000026682, UP000026276, UP000026808, UP000026507, UP000019768, UP000023104, UP000020971, UP000020725, UP000021792, UP000020525, UP000011983, UP000012031 491158342, 695928603, 627855911, 627854560, 627852232, 627845411, 627838758, 620738296, 620731734, 620724604, 620723314, 620718025, 605568397, 595855794, 588976914, 585214362, 585210192, 585206254, 451922767, 451921625 AIT25804.1, KCV15528.1, KCV14354.1, KCV12358.1, KCV06386.1, KCV00523.1, KAK96366.1, KAK89921.1, KAK83129.1, KAK81903.1, KAK76870.1, AHV91631.1, EXX95624.1, EXF89416.1, EWM50533.1, EWM46370.1, EWM42435.1, EMD72911.1, EMD71770.1 WP_005016729.1 fig|1281885.3.peg.2735, fig|1172205.4.peg.3051, fig|1266729.3.peg.2788 636 637 yes 1892235 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29497 Vibrio splendidus Bacteria UP000050463 515660035 WP_017092635.1 640 649 yes 1892236 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 300, 1225174 Pseudomonas mendocina, Pseudomonas mendocina S5.2 Bacteria UP000028008, UP000028530 515932726, 667952404, 663687665 KFB13276.1, KES02821.1 WP_017363309.1 627 627 yes 1892237 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1165090, 946077 Imtechella halotolerans, Imtechella halotolerans K1 Bacteria UP000005938 495515161, 383834991 EID74422.1 WP_008239806.1 fig|946077.3.peg.1884 611 611 yes 1892238 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1282361 Asticcacaulis sp. AC402 Bacteria UP000017812 557336922 ESQ76732.1 614 618 yes 1892239 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 290336 Klebsiella oxytoca M5al Bacteria UP000002841 410374067 EKP28749.1 fig|290336.4.peg.1217 626 631 yes 1892240 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 151081 Pseudoalteromonas ruthenica Bacteria UP000033402 551325999 WP_022945442.1 645 649 yes 1892241 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1299334 Mycobacterium xenopi 4042 Bacteria 576475185 EUA68731.1 144 145 no 1892242 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287252 Mesorhizobium sp. LNHC252B00 Bacteria UP000020180 563147862 ESY71647.1 605 619 yes 1892243 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 129789, 1227491 Natrialba aegyptia, Natrialba aegyptia DSM 13077 Archaea 493714984, 445654564 ELZ07415.1 WP_006664547.1 M0B9B7 M0B9B7_9EURY 451 464 yes 1892244 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 136993 Methylosinus sp. LW4 Bacteria 517077380 WP_018266198.1 610 610 yes 1892245 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169156 Streptomyces sp. CNB091 Bacteria 517787152 WP_018957360.1 581 606 yes 1892246 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314264 Roseovarius sp. 217 Bacteria UP000004087 497505632, 85670067 EAQ24930.1 WP_009819830.1 fig|314264.3.peg.4780 597 600 yes 1892247 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 347 Xanthomonas oryzae Bacteria UP000037499 518133823 WP_019304031.1 624 625 yes 1892248 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 339, 990315 Xanthomonas campestris, Xanthomonas campestris pv. raphani 756C Bacteria UP000037537, UP000001633 504321779, 341938370 AEL08509.1 WP_014508881.1 fig|990315.4.peg.3436 623 625 yes 1892249 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 847, 556269 Oxalobacter formigenes, Oxalobacter formigenes OXCC13 Bacteria UP000005089 492548411, 229380518 EEO30609.1 WP_005881923.1 636 637 yes 1892250 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817, 1339280, 1339281 Bacteroides fragilis, Bacteroides fragilis str. 2-F-2 # 4, Bacteroides fragilis str. 2-F-2 #5 Bacteria UP000036847, UP000022272, UP000022569 695473576, 596077840, 595896536 EXZ44281.1, EXY17852.1 WP_032570708.1 564 564 yes 1892251 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1261057 Gardnerella vaginalis JCP7275 Bacteria UP000014557 514596474 EPI57246.1 609 872 yes 1892252 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 186931, 1255043 Thioalkalivibrio nitratireducens, Thioalkalivibrio nitratireducens DSM 14787 Bacteria UP000010809 505073380, 430012638 AGA35390.1 WP_015260482.1 fig|1255043.3.peg.3797 625 629 yes 1892253 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992183 Yersinia pestis, Yersinia pestis PY-102 Bacteria UP000000815 UP000031825, UP000003430 488360027, 391722868 EIT52625.1 WP_002429412.1 206 225 no 1892254 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 75906 Thermocrinis ruber Bacteria UP000018914 644376309, 570725525 AHE96841.1 WP_025306123.1 121 122 no 1892255 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 626 631 yes 1892256 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 271155 Flavobacterium antarcticum Bacteria 551199256 WP_022827321.1 619 619 yes 1892257 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 219305 Micromonospora sp. ATCC 39149 Bacteria UP000010307 494133233, 237882890 EEP71718.1 WP_007072994.1 fig|219305.4.peg.1193 530 530 yes 1892258 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 525283 Fusobacterium nucleatum, Fusobacterium nucleatum subsp. nucleatum ATCC 23726 Bacteria UP000003643 492615452, 296153695 EFG94512.1 WP_005904282.1 433 433 yes 1892259 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 174633 Candidatus Kuenenia stuttgartiensis Bacteria 91200875 411 412 yes 1892260 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 667585 Burkholderia sp. JPY251 Bacteria 517246470 WP_018435288.1 642 643 yes 1892261 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66821, 1150621 Sulfurospirillum multivorans, Sulfurospirillum multivorans DSM 12446 Bacteria UP000019322 644631714, 584601341 AHJ11993.1 WP_025343901.1 621 622 yes 1892262 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28126, 575611 Prevotella buccae, Prevotella buccae D17 Bacteria UP000005080 490472599, 288336541 EFC74914.1 WP_004343050.1 527 529 yes 1892263 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992185, 992178, 992176, 992173, 992170, 992162, 992139 Yersinia pestis, Yersinia pestis PY-113, Yersinia pestis PY-96, Yersinia pestis PY-94, Yersinia pestis PY-91, Yersinia pestis PY-88, Yersinia pestis PY-61, Yersinia pestis PY-13 Bacteria UP000000815 UP000031825, UP000006018, UP000005421, UP000005691, UP000003605, UP000003581, UP000003504, UP000004911 488327075, 391726249, 391691871, 391676168, 391666337, 391648718, 391609945, 391485278 EIT55624.1, EIT24762.1, EIT10606.1, EIT01820.1, EIS86198.1, EIS52292.1, EIR41441.1 WP_002396460.1 179 204 no 1892264 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702, 1261066 Gardnerella vaginalis, Gardnerella vaginalis JCP8108 Bacteria UP000037770, UP000014521 515213359, 514587190 EPI49065.1 WP_016812928.1 609 872 yes 1892265 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 454602 gamma proteobacterium CL-CB221 Bacteria 551339255 WP_022958675.1 625 628 yes 1892266 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 551 552 yes 1892267 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2251, 1227458, 1230452 Haloferax alexandrinus JCM 10717, Haloferax lucentense DSM 14919 Archaea 490164083, 445736467, 445723601 ELZ88011.1, ELZ75238.1 WP_004062734.1 M0GUI4, M0HU73 M0GUI4_HALL2, M0HU73_9EURY 437 465 yes 1892268 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 592316 Pantoea sp. At-9b Bacteria UP000001624 503272749, 316948066 ADU67541.1 WP_013507410.1 fig|592316.3.peg.5398 631 641 yes 1892269 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 636, 667121 Edwardsiella tarda, Edwardsiella tarda ATCC 15947 Bacteria UP000035028, UP000011707 491439815, 451313625 WP_005297608.1 fig|500638.3.peg.9, fig|1216965.3.peg.3225, fig|667121.5.peg.2376 630 642 yes 1892270 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 183, 929563 Leptonema illini, Leptonema illini DSM 21528 Bacteria UP000005737 488860729, 373875234 EHQ07228.1 WP_002772968.1 600 602 yes 1892271 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204037 568600107 WP_024104189.1 631 655 yes 1892272 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1127744 Bacillus sp. JS Bacteria UP000005213 504476187, 384930831 AFI27509.1 WP_014663289.1 fig|1127744.3.peg.943 590 590 yes 1892273 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 590061 Halomonas sp. KM-1 Bacteria 498315213 WP_010629369.1 629 629 yes 1892274 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54076 Thermococcus zilligii Archaea 498163645 WP_010477801.1 427 428 yes 1892275 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173, 1193044 Leptospira interrogans, Leptospira interrogans serovar Valbuzzi str. Valbuzzi Bacteria UP000037872, UP000017040 498364721, 478979946 ENO73506.1 WP_010678877.1 491 495 yes 1892276 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47951 Vibrio cyclitrophicus Bacteria 515166150 WP_016794676.1 640 649 yes 1892277 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39946 Oryza sativa Indica Group Plants UP000007015 125545258 EAY91397.1 560 588 yes 1892278 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 126385, 1256991, 1256993 Providencia alcalifaciens, Providencia alcalifaciens PAL-1, Providencia alcalifaciens PAL-3 Bacteria UP000020955, UP000019057 739082438, 577061538, 573499112 EUC98600.1, ETS99622.1 WP_036953595.1 623 655 yes 1892279 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2769 Chondrus crispus Plants 546301211, 507107591 XP_005711339.1 555 616 yes 1892280 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1511 Clostridium sticklandii Bacteria 503127558, 308826089 WP_013362219.1 fig|499177.3.peg.1995 436 436 yes 1892281 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 1445864 Serratia marcescens, Serratia marcescens BIDMC 80 Bacteria UP000055021, UP000023903 727188163, 839837510, 612272601 KMJ09881.1, EZQ66086.1 WP_033649986.1 632 647 yes 1892282 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29419, 1357399 Helicobacter canis, Helicobacter canis NCTC 12740 Bacteria UP000018688 565846724, 564727874 ETD27852.1 WP_023929704.1 451 452 yes 1892283 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298608 Psychrobacter sp. JCM 18900 Bacteria UP000019500 589900575 660 678 yes 1892284 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 185294 Prevotella paludivivens Bacteria 517274601 WP_018463419.1 528 529 yes 1892285 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 514851322 WP_016596415.1 448 459 yes 1892286 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 457427 Streptomyces hygroscopicus ATCC 53653 Bacteria UP000003963 302461639 EFL24732.1 589 592 yes 1892287 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4577 Zea mays Plants UP000007305 226532305, 195649785 ACG44360.1 NP_001151805.1 551 643 yes 1892288 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1078505 Paenibacillus sp. HGH0039 Bacteria UP000014406 512467949, 512146109 EPD88648.1 WP_016423639.1 fig|1078505.3.peg.2177 591 591 yes 1892289 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1156841 Streptomyces sp. ScaeMP-e10 Bacteria 517338343 WP_018513835.1 592 601 yes 1892290 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1223543 Gordonia paraffinivorans NBRC 108238 Bacteria UP000035021 453379298 fig|1223543.3.peg.3816 549 560 yes 1892291 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44930, 797304 Natronobacterium gregoryi, Natronobacterium gregoryi SP2 Archaea UP000011613 491747708, 429192961, 445609860, 429137179 ELY63646.1, AFZ74190.1 WP_005580841.1, YP_007178639.1 L0AMC2 L0AMC2_NATGS 458 468 yes 1892292 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173780 Salmonella enterica, Salmonella enterica subsp. diarizonae serovar 60:r:e,n,x,z15 str. 01-0170 Bacteria UP000054489, UP000017605 555266440, 554386046 ESJ18013.1 WP_023247918.1 626 631 yes 1892293 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1002339 Psychrobacter sp. 1501(2011) Bacteria UP000004919 494636985, 332975650 EGK12539.1 WP_007394929.1 658 666 yes 1892294 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 69525, 797303 Natrinema pellirubrum, Natrinema pellirubrum DSM 15624 Archaea UP000010843 493184641, 433592282, 445622170, 433307062 ELY75634.1, AGB32874.1 WP_006181278.1, YP_007281778.1 L0JNQ2 L0JNQ2_NATP1 453 481 yes 1892295 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547045 Neisseria sicca ATCC 29256 Bacteria UP000005365 255048053 EET43517.1 fig|547045.3.peg.2202 318 318 yes 1892296 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 545275 Thioalkalivibrio sp. ALE20 Bacteria 518420672 WP_019590879.1 627 629 yes 1892297 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702, 682148 Gardnerella vaginalis, Gardnerella vaginalis 5-1 Bacteria UP000037770, UP000004859 490210281, 297533070 EFH71954.1 WP_004108681.1 608 876 yes 1892298 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 311400, 69014 Thermococcus kodakarensis, Thermococcus kodakarensis KOD1 Archaea UP000000536 UP000000536 499568605, 73620925, 57158692 WP_011249388.1 Q5JD26 THIC_THEKO Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 938637 fig|69014.3.peg.318 428 428 yes 1892299 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 347481, 1121022 Asticcacaulis benevestitus, Asticcacaulis benevestitus DSM 16100 = ATCC BAA-896 Bacteria UP000017837 516746693, 557341917 ESQ81603.1 WP_018079691.1 617 618 yes 1892300 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 435897, 1444315 Lysobacter capsici, Lysobacter capsici AZ78 Bacteria UP000059881, UP000023435 738153865, 601089015 EYR66815.1 WP_036111234.1 625 628 yes 1892301 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 347, 129394, 383407 Xanthomonas oryzae, Xanthomonas oryzae pv. oryzicola, Xanthomonas oryzae pv. oryzicola BLS256 Bacteria UP000037499, UP000035998, UP000008851 504317400, 856765450, 856759884, 856754842, 856734626, 856730585, 353463523 AKO20943.1, AKO17123.1, AKO13382.1, AKN98157.1, AKN94433.1, AEQ97802.1 WP_014504502.1 624 625 yes 1892302 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 251221, 33072 Gloeobacter violaceus PCC 7421, Gloeobacter violaceus Bacteria UP000000557 UP000000557 37520687, 499453654, 47606110, 35211681 NP_924064.1, WP_011141118.1 Q7NLK5 THIC_GLOVI Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 523198 fig|251221.1.peg.1118 456 459 yes 1892303 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 883120 Klebsiella oxytoca, Klebsiella oxytoca 10-5245 Bacteria UP000030350, UP000003205 490218734, 376376116 EHS88899.1 WP_004117111.1 fig|883120.3.peg.5220 626 631 yes 1892304 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 588 606 yes 1892305 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446754 Escherichia coli, Escherichia coli O69:H11 str. 2009C-3601 Bacteria UP000036210, UP000024297 693204616, 607738009 EZE19878.1 WP_032324993.1 626 631 yes 1892306 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1049, 572477 Allochromatium vinosum, Allochromatium vinosum DSM 180 Bacteria UP000001441 502734322, 288895194 ADC61030.1 WP_012969306.1 fig|572477.4.peg.59 627 630 yes 1892307 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 777 Coxiella burnetii Bacteria UP000033654 515822129 WP_017252882.1 546 554 yes 1892308 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1008460, 529709 Pyrococcus yayanosii, Pyrococcus sp. CH1 Archaea UP000008386 503671294, 334900045 AEH24313.1 WP_013905370.1 F8AI83 F8AI83_PYRYC 430 430 yes 1892309 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2201, 28892 Methanofollis liminatans, Methanofollis liminatans DSM 4140 Archaea UP000005095 490137979, 395442079 EJG06836.1 WP_004038336.1 J0RZ79 J0RZ79_9EURY 419 424 yes 1892310 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168697 Salinispora arenicola Bacteria 518742398 WP_019901137.1 530 530 yes 1892311 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 379097, 945550 Vibrio sinaloensis, Vibrio sinaloensis DSM 21326 Bacteria UP000031444, UP000006228 495356256, 323315309 EGA68352.1 WP_008080977.1 640 646 yes 1892312 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 302406, 1247726 Tetrathiobacter kashmirensis, Advenella mimigardefordensis DPN7 Bacteria UP000019095 644867190, 575432730 AHG65036.1 WP_025373695.1 636 637 yes 1892313 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 1308980, 1006551 Klebsiella oxytoca, Klebsiella oxytoca HKOPL1, Klebsiella oxytoca KCTC 1686 Bacteria UP000030350, UP000023763, UP000007843 503993505, 612156433, 365907868 AHW85922.1, AEX03321.1 WP_014227499.1 fig|1006551.4.peg.1603 626 631 yes 1892314 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 243232 Methanocaldococcus jannaschii DSM 2661 Archaea UP000000805 UP000000805 1591682 AAB99030.1 Q58432 THIC_METJA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 9617 fig|243232.1.peg.1057 432 438 yes 1892315 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 171549, 999417, 469591, 469592 Parabacteroides distasonis CL09T03C24, Bacteroides sp. 20_3, Bacteroides sp. 3_1_19 Bacteria UP000006262, UP000006014, UP000005120 492488467, 409240975, 300831833, 298268150 EKN33749.1, EFK62464.1, EFI09806.1 WP_005862332.1 fig|469592.4.peg.1833, fig|999417.3.peg.196 565 565 yes 1892316 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 298701 Desulfovibrio sp. A2 Bacteria UP000003780 494785972, 347520359 EGY27494.1 WP_007521380.1 fig|298701.3.peg.201 419 429 no 1892317 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 79209, 768704 Desulfosporosinus meridiei, Desulfosporosinus meridiei DSM 13257 Bacteria UP000005262 504717134, 402255052 AFQ45327.1 WP_014904236.1 420 426 yes 1892318 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 79209, 768704 Desulfosporosinus meridiei, Desulfosporosinus meridiei DSM 13257 Bacteria UP000005262 504717135, 402255053 AFQ45328.1 WP_014904237.1 422 432 yes 1892319 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 74319, 1280954 Hyphomonas polymorpha, Hyphomonas polymorpha PS728 Bacteria UP000027100 737630224, 630951286 KCZ97431.1 WP_035600335.1 621 631 yes 1892320 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294, 216595 Pseudomonas fluorescens, Pseudomonas fluorescens SBW25 Bacteria UP000060991, UP000002332 502154566, 229359913 WP_012721889.1 fig|216595.4.peg.731 628 634 yes 1892321 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2271, 768679 Thermoproteus tenax, Thermoproteus tenax Kra 1 Archaea UP000002654 503892226, 352681519, 350274318 WP_014126220.1, YP_004892043.1 G4RN19 G4RN19_THETK 420 429 no 1892322 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 199, 1243032 Campylobacter concisus, Campylobacter concisus ATCC 51561 Bacteria UP000066049, UP000016619 544656287, 543208314 ERJ27465.1 WP_021089983.1 431 431 yes 1892323 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 210512 Sandarakinorhabdus limnophila Bacteria 550930700 WP_022679149.1 612 614 yes 1892324 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 633149 Brevundimonas subvibrioides ATCC 15264 Bacteria UP000002696 302194943 ADL02515.1 fig|633149.3.peg.1532 622 639 yes 1892325 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314281, 87626 Pseudoalteromonas tunicata, Pseudoalteromonas tunicata D2 Bacteria UP000006201 497523986, 88819108 EAR28922.1 WP_009838184.1 fig|87626.3.peg.3259 645 653 yes 1892326 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1306787, 391936 Alcanivorax pacificus, Alcanivorax sp. W11-5 Bacteria UP000006764 496014753, 745804189 AJD46890.1 WP_008739332.1 fig|391936.3.peg.3372 623 626 yes 1892327 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1190, 741277 Fischerella sp. JSC-11 Bacteria UP000004344 497074560, 353539438 EHC08925.1 WP_009459862.1 fig|741277.3.peg.3806 457 459 yes 1892328 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 441 487 yes 1892329 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39490, 1256908, 1262949 Eubacterium ramulus, Eubacterium ramulus ATCC 29099, Roseburia sp. CAG:50 Bacteria, Environmental samples UP000016608, UP000018378 545615353, 544239155, 524195840 ERK51842.1 WP_021739452.1 435 436 yes 1892330 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1202457 Bacillus sp. CPSM8 Bacteria UP000018544 564403140 ETB70628.1 591 591 yes 1892331 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 122355 Pseudomonas psychrophila Bacteria UP000036341 518240916 WP_019411124.1 627 629 yes 1892332 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144312 Rhizobium sp. CF122 Bacteria UP000007285 495069719, 398062167 EJL53948.1 WP_007794544.1 fig|1144312.3.peg.2822 601 608 yes 1892333 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 514853202 WP_016598109.1 651 681 yes 1892334 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28174 Vibrio ordalii Bacteria 498005266 WP_010319422.1 640 649 yes 1892335 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1173032, 1173020 Chamaesiphon minutus, Chamaesiphon minutus PCC 6605 Bacteria UP000010366 504973548, 428018430 AFY94524.1 WP_015160650.1 fig|1173020.3.peg.4059 456 459 yes 1892336 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158148 Thioalkalivibrio sp. ARh3 Bacteria 517692963 WP_018863171.1 627 629 yes 1892337 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 527012 Yersinia kristensenii ATCC 33638 Bacteria UP000003177 238696463 EEP89254.1 639 694 yes 1892338 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310684 Acinetobacter baumannii, Acinetobacter baumannii 83444 Bacteria UP000028632, UP000023026 691161618, 588207831 EXE80681.1 WP_032069070.1 621 625 yes 1892339 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 441 515 yes 1892340 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 1120924, 62977 Acinetobacter baylyi DSM 14961 = CIP 107474, Acinetobacter sp. ADP1 Bacteria UP000018449, UP000000430 491059041, 480011461, 81613383, 49529529 ENV52890.1 WP_004920677.1 Q6FFB6 THIC_ACIAD Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 587786 fig|1221291.3.peg.1323, fig|62977.3.peg.617, fig|1120924.3.peg.3268 626 631 yes 1892341 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1260, 768713 Finegoldia magna, Finegoldia magna ACS-171-V-Col3 Bacteria UP000003650 488925838, 302312732 EFK94726.1 WP_002836913.1 433 433 yes 1892342 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632, 992167, 992157, 992149, 992146, 992136, 992133 Yersinia pestis, Yersinia pestis PY-71, Yersinia pestis PY-55, Yersinia pestis PY-42, Yersinia pestis PY-32, Yersinia pestis PY-10, Yersinia pestis PY-07 Bacteria UP000000815 UP000031825, UP000005703, UP000004223, UP000003689, UP000003270, UP000003852, UP000003285 488312064, 391633723, 391579870, 391534615, 391519302, 391469426, 391453537 EIS73089.1, EIS25938.1, EIR85779.1, EIR71948.1, EIR27205.1, EIR12842.1 WP_002381449.1 178 202 no 1892343 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1125642 Escherichia coli, Escherichia coli P0301867.13 Bacteria UP000036210, UP000012356 486158612, 477106994 END87200.1 WP_001522286.1 fig|1125642.3.peg.4576 626 631 yes 1892344 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1384484 Adlercreutzia equolifaciens DSM 19450 Bacteria UP000015924 530778671 461 464 yes 1892345 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1205910 Nocardiopsis alba ATCC BAA-2165 Bacteria UP000003779 402799044 AFR06454.1 fig|1205910.3.peg.822 507 543 yes 1892346 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1177712, 634177 Gluconacetobacter medellensis, Gluconacetobacter xylinus NBRC 3288 Bacteria UP000009044 503871944, 347580200 WP_014105938.1 605 613 yes 1892347 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1286093 Pandoraea sp. SD6-2 Bacteria UP000013879 498506383, 490314116 EON12439.1 WP_010807046.1 fig|1286093.3.peg.3429 637 638 yes 1892348 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262892 Eubacterium sp. CAG:76 Environmental samples UP000018156 548312085, 524814876 WP_022502543.1 434 435 yes 1892349 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1104682 Pseudomonas syringae pv. actinidiae ICMP 18804 Bacteria UP000015681 519225964 EPN07468.1 103 103 no 1892350 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 416001 Leptolyngbya nodulosa Bacteria 515868296 WP_017298920.1 460 462 yes 1892351 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2173 Methanobrevibacter smithii Archaea 518097548 WP_019267756.1 423 424 yes 1892352 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 936589 Veillonella sp. AS16 Bacteria UP000019042 740277344, 573491310 ETS92124.1 WP_038117435.1 434 434 yes 1892353 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 59538 Pantholops hodgsonii Mammals 556763291 XP_005976929.1 461 468 no 1892354 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 541095 Corynebacterium lubricantis Bacteria 517108404 WP_018297222.1 571 576 yes 1892355 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158762 Thioalkalivibrio sp. ALJ16 Bacteria 517701432 WP_018871640.1 627 629 yes 1892356 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3218 Physcomitrella patens Plants UP000006727 UP000006727 168064850, 162664107 EDQ50840.1 XP_001784371.1 557 598 yes 1892357 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29362, 588581 Clostridium papyrosolvens, Clostridium papyrosolvens DSM 2782 Bacteria UP000003860 490755205, 325987641 EGD48467.1 WP_004617507.1 436 436 yes 1892358 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1232426 Collinsella sp. GD3 Bacteria 518068704 WP_019238912.1 464 465 yes 1892359 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 447471, 1117647 Simiduia agarivorans, Simiduia agarivorans SA1 = DSM 21679 Bacteria UP000000466 504860467, 409027121 AFU99405.1 WP_015047569.1 633 634 yes 1892360 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1173027 Microcoleus sp. PCC 7113 Bacteria UP000010471 504995082, 428252073 AFZ18032.1 WP_015182184.1 fig|1173027.3.peg.2421 455 457 yes 1892361 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444243 Escherichia coli, Escherichia coli 1-110-08_S4_C2 Bacteria UP000036210, UP000022584 693050041, 598688031 EYD94960.1 WP_032219408.1 626 631 yes 1892362 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65553, 525898 Sulfurospirillum deleyianum, Sulfurospirillum deleyianum DSM 6946 Bacteria UP000002222 502619496, 268617221 ACZ11586.1 WP_012856352.1 fig|525898.4.peg.368 620 622 yes 1892363 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1051353 Escherichia coli, Escherichia coli ATCC 700728 Bacteria UP000036210, UP000011590 487447466, 444588594 ELV63966.1 WP_001691091.1 fig|1051353.3.peg.4670 626 631 yes 1892364 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217702 Acinetobacter sp. NIPH 1867 Bacteria UP000013195 491352142, 480333837 ENX54059.1 WP_005210064.1 fig|1217702.3.peg.1295 626 631 yes 1892365 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29760 Vitis vinifera Plants UP000009183 UP000009183 731391934, 225434668, 297745941 XP_010650932.1, XP_002280227.1 551 640 yes 1892366 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316, 1333856 Pseudomonas stutzeri, Pseudomonas stutzeri MF28 Bacteria UP000037382, UP000016090 544787276, 533218713 EQM73754.1 WP_021209722.1 626 626 yes 1892367 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 166318 Synechococcus sp. WH 8016 Bacteria UP000002752 493908266, 351679292 EHA62434.1 WP_006853865.1 fig|166318.3.peg.1851 458 467 yes 1892368 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3055 Chlamydomonas reinhardtii Plants UP000006906 UP000006906 159479350, 568760861, 158274124 AHE23991.1, EDO99908.1 XP_001697756.1 567 637 yes 1892369 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263014 Firmicutes bacterium CAG:270 Environmental samples UP000018350 548033070, 524662095 WP_022374405.1 433 433 yes 1892370 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 118173 Pseudanabaena sp. PCC 6802 Bacteria 518332567 WP_019502774.1 455 457 yes 1892371 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 568817 Serratia symbiotica str. 'Cinara cedri' Bacteria UP000013561 363988635 AEW44826.1 fig|568817.3.peg.714 634 648 yes 1892372 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 102134, 767817 Desulfotomaculum gibsoniae, Desulfotomaculum gibsoniae DSM 7213 Bacteria UP000013520 493567990, 488454726 AGL00620.1 WP_006521286.1 420 426 yes 1892373 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1334193, 701347 Enterobacter lignolyticus, Enterobacter cloacae SCF1 Bacteria UP000006872 503133452, 308750646 ADO50398.1 WP_013368113.1 fig|701347.4.peg.4243 626 631 yes 1892374 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61645, 1421338 Enterobacter asburiae, Enterobacter asburiae L1 Bacteria UP000036088, UP000023748 658549741, 612153452 AHW96123.1 WP_029742116.1 626 631 yes 1892375 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3847 Glycine max Plants UP000008827 UP000008827 571543621 XP_006602098.1 548 646 yes 1892376 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106633 518393632 WP_019563839.1 627 629 yes 1892377 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 861109 Sphingobium indicum B90A Bacteria UP000004550 389590420 EIM68412.1 fig|861109.3.peg.1156 603 610 yes 1892378 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1049780, 1049786 Leptospira borgpetersenii str. Brem 328, Leptospira borgpetersenii str. Brem 307 Bacteria UP000012166, UP000012110 464197935, 464193738 EMN15820.1, EMN13091.1 290 306 no 1892379 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 136849, 1154761, 1154762 Pseudomonas syringae pv. avellanae str. ISPaVe013, Pseudomonas syringae pv. avellanae str. ISPaVe037 Bacteria UP000007351, UP000007131 489509582, 408003060, 408000584 EKG43275.1, EKG40934.1 WP_003414443.1 fig|1154761.3.peg.585, fig|1154762.3.peg.575 627 629 yes 1892380 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 683150 Arthrobacter sp. SJCon Bacteria UP000011189 496737894, 443482986 ELT45891.1 WP_009356576.1 fig|683150.5.peg.581 488 497 yes 1892381 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 504092 Kushneria aurantia Bacteria 518794009 WP_019951298.1 633 635 yes 1892382 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144320 Pantoea sp. GM01 Bacteria UP000007295 495161486, 398101971 EJL92167.1 WP_007886285.1 fig|1144320.3.peg.750 631 641 yes 1892383 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396, 269801 Bacillus cereus, Bacillus cereus G9241 Bacteria UP000036076, UP000003555 487905926, 753562924, 753363525, 728881934, 633261519, 47553631 AJI05889.1, AJG96449.1, AIY77721.1, KDB40082.1, EAL12008.1 WP_001979392.1 fig|269801.1.peg.5140 586 586 yes 1892384 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 661, 314292 Photobacterium angustum, Photobacterium angustum S14 Bacteria UP000032575, UP000001603 491514767, 90437712 EAS62903.1 WP_005372400.1 fig|314292.13.peg.631 636 639 yes 1892385 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1435356 Rhodococcus pyridinivorans SB3094 Bacteria UP000018781 568234577 AHD21482.1 571 594 yes 1892386 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 80871, 927661 Cryptosporangium arvum, Cryptosporangium arvum DSM 44712 Bacteria UP000021053 737882390, 589395355 EXG80112.1 WP_035848898.1 515 518 yes 1892387 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 199, 1242967 Campylobacter concisus, Campylobacter concisus UNSW1 Bacteria UP000066049, UP000016654 544651966, 543204096 ERJ23401.1 WP_021085924.1 432 432 yes 1892388 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 243261 Burkholderia sp. Ch1-1 Bacteria UP000005779 494326665, 385181193 EIF30469.1 WP_007181184.1 642 643 yes 1892389 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 32025, 235279 Helicobacter hepaticus, Helicobacter hepaticus ATCC 51449 Bacteria UP000002495 499428957, 32263132, 47606129 AAP78178.1 WP_011116421.1 Q7VFU4 THIC_HELHP Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 529951 fig|235279.1.peg.1581 457 457 yes 1892390 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317, 1189623 Pseudomonas syringae, Pseudomonas syringae pv. actinidiae ICMP 18886 Bacteria UP000028642, UP000015744 520883860, 519197954 EPM84037.1 WP_020314241.1 478 478 yes 1892391 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144324 Pseudomonas sp. GM18 Bacteria UP000007280 495214856, 398125133 EJM14622.1 WP_007939635.1 fig|1144324.3.peg.3569 628 629 yes 1892392 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 58135, 760568 Desulfotomaculum kuznetsovii, Desulfotomaculum kuznetsovii DSM 6115 Bacteria UP000054111, UP000009229 503587600, 333821498 AEG14161.1 WP_013821676.1 fig|760568.4.peg.598 433 433 yes 1892393 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 211669 Psychromonas hadalis Bacteria 551320795 WP_022940571.1 645 664 yes 1892394 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263022 Firmicutes bacterium CAG:424 Environmental samples UP000018167 547861286, 524505895 WP_022267917.1 438 440 yes 1892395 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 931 Thiobacillus thioparus Bacteria 517331961 WP_018507453.1 646 647 yes 1892396 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1313067 Williamsia sp. D3 Bacteria UP000018666 564758142 ETD33378.1 538 555 yes 1892397 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197, 683082 Campylobacter jejuni, Campylobacter jejuni subsp. jejuni 1336 Bacteria UP000065538, UP000001403 488950120, 283792535 EFC31314.1 WP_002861195.1 430 430 yes 1892398 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1764, 1770, 1335418, 1391995, 1391996, 1391997, 1392002, 1199187, 262316 Mycobacterium avium, Mycobacterium avium subsp. paratuberculosis, Mycobacterium avium MAV_061107_1842, Mycobacterium avium subsp. paratuberculosis 10-5975, Mycobacterium avium subsp. paratuberculosis 10-5864, Mycobacterium avium subsp. paratuberculosis 10-4404, Mycobacterium avium 05-4293, Mycobacterium avium subsp. paratuberculosis MAP4, Mycobacterium avium subsp. paratuberculosis K-10 Bacteria UP000031877, UP000020016, UP000031934, UP000035059, UP000035041, UP000018553, UP000013540, UP000000580 499252624, 756085452, 756076426, 576355154, 564187139, 564154700, 564151793, 564145423, 494539982, 330463122, 41398844, 47606074 AJK81247.1, AJK77023.1, ETZ49565.1, ETB26644.1, ETA99173.1, ETA96547.1, ETA90529.1, AGL38871.1, AEC30365.1, AAS06463.1 WP_010950164.1 P61426 THIC_MYCPA Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 537849 fig|1078005.3.peg.3590, fig|262316.1.peg.3913, fig|1078003.3.peg.4298, fig|1029814.3.peg.1689, fig|1078002.3.peg.92, fig|1078004.3.peg.4309, fig|1029813.3.peg.4021, fig|1199187.3.peg.4155, fig|1029821.3.peg.4056, fig|1010838.3.peg.1675, fig|1029818.3.peg.1792 538 540 yes 1892399 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444258 Escherichia coli, Escherichia coli 2-005-03_S4_C3 Bacteria UP000036210, UP000024243 693163293, 611030131 EZJ34291.1 WP_032297846.1 626 631 yes 1892400 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 1095678 Neisseria meningitidis, Neisseria meningitidis 63049 Bacteria UP000050419, UP000010765 488178283, 432245324 ELL00794.1 WP_002249491.1 fig|1095678.3.peg.2625 625 633 yes 1892401 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263088 Methanobrevibacter smithii CAG:186 Archaea UP000018189 548644642, 524836932 WP_022531271.1 R7PTQ0 R7PTQ0_9EURY 423 424 yes 1892402 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33, 483219 Myxococcus fulvus, Myxococcus fulvus HW-1 Bacteria UP000000488 503706765, 337261584 AEI67744.1 WP_013940841.1 fig|483219.12.peg.5901 621 624 yes 1892403 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 915, 228410 Nitrosomonas europaea, Nitrosomonas europaea ATCC 19718 Bacteria UP000001416 499423226, 47606152, 30179954 WP_011110690.1 Q82Y50 THIC_NITEU Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 366787 fig|228410.1.peg.38 629 632 yes 1892404 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1227480, 1227481 Halorubrum hochstenium, Halorubrum hochstenium ATCC 700873 Archaea 495856174, 445710344 ELZ62163.1 WP_008580753.1 M0FS69 M0FS69_9EURY 452 482 yes 1892405 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1261622 Thioalkalivibrio sp. ALJ2 Bacteria 517824288 WP_018994496.1 627 629 yes 1892406 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1302425 Clostridium botulinum CFSAN002367 Bacteria UP000015064 526258475 EPS51030.1 437 437 yes 1892407 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 906, 1000568, 699218 Megasphaera sp. UPII 199-6, Megasphaera genomosp. type_1 str. 28L Bacteria UP000004018, UP000003242 494632626, 333764723, 290781098 EGL42109.1, EFD93689.1 WP_007390570.1 433 433 yes 1892408 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446669, 1446670 Escherichia coli, Escherichia coli O157:H7 str. K1921, Escherichia coli O157:H7 str. K1927 Bacteria UP000036210, UP000023807, UP000023978 692976162, 607494633, 607494586 EZB83649.1, EZB83604.1 WP_032167760.1 626 631 yes 1892409 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 861266 Arthrobacter sp. 4J27 Bacteria UP000035722 635352520 591 608 yes 1892410 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 382 Sinorhizobium meliloti Bacteria UP000028953 516776526 WP_018096098.1 603 611 yes 1892411 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 38312, 1273125 Rhodococcus rhodnii, Rhodococcus rhodnii LMG 5362 Bacteria UP000013525 498803947, 488680130 EOM74343.1 WP_010840354.1 fig|1273125.3.peg.4122 541 550 yes 1892412 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1553, 1230342 Clostridium tetanomorphum, Clostridium tetanomorphum DSM 665 Bacteria UP000025063 737161654, 618852531, 618850276 KAJ51756.1, KAJ49587.1 WP_035148178.1 437 437 yes 1892413 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 174, 280505, 1049781, 1049762 Leptospira borgpetersenii, Leptospira borgpetersenii serovar Ballum, Leptospira borgpetersenii str. Noumea 25, Leptospira borgpetersenii serovar Castellonis str. 200801910 Bacteria UP000029690, UP000012129, UP000001336 488826467, 689448241, 464326455, 410749010 KGE22390.1, EMO10843.1, EKR01903.1 WP_002738873.1 511 511 yes 1892414 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 75906 Thermocrinis ruber Bacteria UP000018914 644376593, 570724825 AHE96141.1 WP_025306178.1 453 455 yes 1892415 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1032506 Prevotella sp. MSX73 Bacteria UP000006593 494653694, 400377807 EJP30675.1 WP_007411638.1 fig|1032506.3.peg.1483 532 536 yes 1892416 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46677 Pseudomonas agarici Bacteria UP000063229 515700758 WP_017133358.1 627 629 yes 1892417 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 696864, 696865, 1029985, 1079476, 925128 Salmonella enterica, Salmonella enterica subsp. enterica serovar Enteritidis str. 20037, Salmonella enterica subsp. enterica serovar Enteritidis str. SE10, Salmonella enterica subsp. enterica serovar Enteritidis str. 6.0562-1, Salmonella enterica subsp. enterica serovar Enteritidis str. 62-1976, Salmonella enterica subsp. enterica serovar Enteritidis str. CVM_56-3991 Bacteria UP000054489, UP000011567, UP000011608, UP000010976, UP000010912, UP000010893 487409572, 444868696, 444863963, 435329291, 435323347, 435153242 ELX93313.1, ELX88775.1, ELP00733.1, ELO95409.1, ELN39855.1 WP_001677390.1 fig|696864.3.peg.1583, fig|925128.3.peg.3240, fig|1029985.3.peg.1951, fig|696865.3.peg.3145, fig|1079476.3.peg.3316 626 631 yes 1892418 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 134533, 1217671 Acinetobacter parvus, Acinetobacter parvus NIPH 1103 Bacteria UP000018426 490812192, 479881919 ENU32691.1 WP_004674306.1 fig|1217671.3.peg.2103 626 631 yes 1892419 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 339, 1094186, 1094187, 1184263, 1094185, 1094183, 1094184 Xanthomonas campestris, Xanthomonas campestris pv. musacearum NCPPB 4384, Xanthomonas campestris pv. musacearum NCPPB 4394, Xanthomonas campestris pv. musacearum NCPPB 4392, Xanthomonas campestris pv. musacearum NCPPB 4380, Xanthomonas campestris pv. musacearum NCPPB 2005, Xanthomonas campestris pv. musacearum NCPPB 4379 Bacteria UP000037537, UP000028170, UP000028173, UP000028174, UP000028169, UP000028168, UP000028166 498063029, 667161834, 667147447, 667144433, 667134633, 667133093, 667131701 KFA36262.1, KFA22732.1, KFA19902.1, KFA10520.1, KFA09031.1, KFA07683.1 WP_010377185.1 624 625 yes 1892420 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28173, 1238442, 1238450, 1238444, 1238443 Vibrio nigripulchritudo, Vibrio nigripulchritudo MADA3020, Vibrio nigripulchritudo SOn1, Vibrio nigripulchritudo MADA3029, Vibrio nigripulchritudo MADA3021 Bacteria UP000033748, UP000018267, UP000018211, UP000018245, UP000018079 550222042, 798718947, 549086588, 549026748, 549009243, 549002753 KJY69591.1 WP_022590274.1 640 646 yes 1892421 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 339854 Bacillus thuringiensis serovar israelensis ATCC 35646 Bacteria UP000005383 74493098 EAO56220.1 591 597 yes 1892422 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144331 Pseudomonas sp. GM49 Bacteria UP000007288 495271803, 398180420 EJM68000.1 WP_007996558.1 fig|1144331.3.peg.2156 628 629 yes 1892423 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1311114 Acinetobacter baumannii 25569_7 Bacteria UP000021150 601360694 EYS11064.1 481 481 yes 1892424 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 495, 546263 Neisseria elongata, Neisseria elongata subsp. glycolytica ATCC 29315 Bacteria UP000005536 489865990, 747149030, 291309941 AJE19413.1, EFE51184.1 WP_003769577.1 625 633 yes 1892425 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1259844 Pseudomonas sp. FGI182 Bacteria UP000018783 644601163, 568241976 AHD16698.1 WP_025340847.1 625 626 yes 1892426 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 756272 Planctomyces brasiliensis DSM 5305 Bacteria UP000006860 324967330 ADY58108.1 fig|756272.4.peg.3391 490 599 yes 1892427 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 343, 1261556 Xanthomonas translucens, Xanthomonas translucens pv. translucens DSM 18974 Bacteria UP000055854, UP000010524 489573021, 430816869 WP_003477467.1 fig|1261556.3.peg.2009 620 625 yes 1892428 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1049766 Leptospira borgpetersenii serovar Javanica str. MK146 Bacteria UP000012134 464254765 EMN59075.1 276 276 no 1892429 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 288022 Kordiimonas gwangyangensis Bacteria 521067403 WP_020399354.1 605 612 yes 1892430 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 667129 Serratia odorifera DSM 4582 Bacteria UP000005723 291423470 EFE96695.1 480 488 yes 1892431 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913069 Salmonella enterica subsp. enterica serovar Baildon str. R6-199 Bacteria UP000003651 357953139 EHJ79796.1 fig|913069.3.peg.4292 352 353 no 1892432 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 38289, 525262 Corynebacterium jeikeium, Corynebacterium jeikeium ATCC 43734 Bacteria UP000004636 491437898, 258603898 EEW17150.1 WP_005295691.1 fig|525262.3.peg.1475 620 641 yes 1892433 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1033854 Thioalkalivibrio sulfidophilus Bacteria 517783874 WP_018954082.1 626 629 yes 1892434 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 540746 Rudaea cellulosilytica Bacteria 517801434 WP_018971642.1 625 632 yes 1892435 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 545264 Thioalkalivibrio sp. AKL11 Bacteria 517770037 WP_018940245.1 626 629 yes 1892436 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 608 881 yes 1892437 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316, 1218352 Pseudomonas stutzeri, Pseudomonas stutzeri KOS6 Bacteria UP000037382, UP000026923 489387331, 582953990 EWC42280.1 WP_003293935.1 627 627 yes 1892438 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33934, 1297581 Anoxybacillus flavithermus, Anoxybacillus flavithermus AK1 Bacteria UP000031249, UP000012085 489492519, 475642027 EMT45787.1 WP_003397463.1 fig|1297581.3.peg.1725 561 562 yes 1892439 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1492, 997898, 1306409 Clostridium butyricum, Clostridium butyricum 60E.3, Clostridium butyricum DKU-01 Bacteria UP000032253, UP000013037, UP000012342 488642594, 480692792, 475997858 ENZ35624.1, EMU55599.1 WP_002579232.1 fig|1306409.3.peg.471, fig|997898.4.peg.208 433 433 yes 1892440 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 293089 Martelella mediterranea Bacteria 516720204 WP_018063464.1 596 600 yes 1892441 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 308865, 238, 1246994, 1117646 Elizabethkingia meningoseptica, Elizabethkingia anophelis R26, Elizabethkingia anophelis Ag1 Bacteria UP000064940, UP000011192, UP000003414 496382811, 668901026, 442562228, 365754248 KFC34747.1, ELR79450.1, EHM96199.1 WP_009091801.1 fig|1117646.3.peg.3599, fig|1246994.3.peg.1950 602 602 yes 1892442 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2176, 547558 Methanohalophilus mahii, Methanohalophilus mahii DSM 5219 Archaea UP000001059 502802320, 294495505, 292666504 ADE36353.1 WP_013037296.1, YP_003541998.1 D5EB02 D5EB02_METMS 10320423 426 426 yes 1892443 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454001 Candidatus Accumulibacter sp. SK-12 Bacteria UP000020218 736935113, 589597539 EXI69554.1 WP_034932193.1 638 638 yes 1892444 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1275976 Salmonella enterica, Salmonella enterica subsp. enterica serovar Newport str. JS09102 Bacteria UP000054489, UP000011771 487656418, 459480727 EMG75222.1 WP_001749431.1 fig|1275976.3.peg.4977 626 631 yes 1892445 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1134413 Bacillus sp. L1(2012) Bacteria 516337547 WP_017727580.1 593 593 yes 1892446 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 453835, 1197174 Alishewanella aestuarii, Alishewanella aestuarii B11 Bacteria UP000012043 495885764, 396086248 EJI83863.1 WP_008610343.1 fig|1197174.4.peg.3190 598 623 yes 1892447 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 59205, 1173948 Salmonella enterica, Salmonella enterica subsp. houtenae, Salmonella enterica subsp. houtenae serovar 50:g,z51:- str. 01-0133 Bacteria UP000054489, UP000017491 554690292, 738574163, 554042959 KHQ77562.1, ESE88681.1 WP_023186795.1 626 631 yes 1892448 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 131540 Thiomicrospira arctica Bacteria 518386128 WP_019556335.1 642 655 yes 1892449 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28123, 910312 Porphyromonas asaccharolytica, Porphyromonas asaccharolytica PR426713P-I Bacteria UP000005800 490461388, 312923054 EFR33875.1 WP_004331955.1 590 590 yes 1892450 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 549, 1261128 Pantoea agglomerans, Pantoea agglomerans 299R Bacteria UP000050560, UP000010936 489946817, 436428229 ELP25888.1 WP_003850124.1 fig|1261128.3.peg.1053 631 640 yes 1892451 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 465543 Streptomyces sp. SPB74 Bacteria UP000002779 295826674 EDY45235.2 560 561 yes 1892452 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 654, 1073382 Aeromonas veronii, Aeromonas veronii AER39 Bacteria UP000051545, UP000004726 491482359, 404613108 EKB10144.1 WP_005340100.1 fig|1073382.3.peg.3555 645 663 yes 1892453 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29488, 1393736 Photorhabdus luminescens, Photorhabdus luminescens BA1 Bacteria UP000029997, UP000023464 738893937, 604177453 EYU14181.1 WP_036781096.1 619 645 yes 1892454 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28095, 999541 Burkholderia gladioli, Burkholderia gladioli BSR3 Bacteria UP000030188, UP000008316 503462553, 327368507 AEA59863.1 WP_013697214.1 fig|999541.3.peg.4724 642 643 yes 1892455 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1263041 Bacteroides coprophilus CAG:333 Environmental samples UP000018018 547870535, 524516926 WP_022276674.1 550 550 yes 1892456 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1764, 1391992 Mycobacterium avium, Mycobacterium avium subsp. avium 11-4751 Bacteria UP000035007 565074624, 564176037 ETB17384.1 WP_023884790.1 465 466 yes 1892457 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851, 469601 Fusobacterium nucleatum, Fusobacterium sp. 21_1A Bacteria UP000004585 496070378, 336163494 EGN66417.1 WP_008794885.1 fig|469601.3.peg.3 433 433 yes 1892458 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1184607 Austwickia chelonae NBRC 105200 Bacteria UP000008495 403190256 fig|1184607.3.peg.2791 566 571 yes 1892459 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 909768, 1310677, 903928 Acinetobacter baumannii 766875, Acinetobacter baumannii OIFC021 Bacteria UP000021394, UP000011665 487980453, 588175592, 444754115 EXE49525.1, ELW78747.1 WP_002053187.1 fig|903928.3.peg.2996 621 625 yes 1892460 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 332953, 1227490 Halovivax asiaticus, Halovivax asiaticus JCM 14624 Archaea 494972088, 445659947 ELZ12747.1 WP_007698114.1 M0BRK1 M0BRK1_9EURY 440 460 yes 1892461 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262777 Clostridium sp. CAG:167 Environmental samples UP000018023 547326051, 524225337 WP_022057044.1 435 435 yes 1892462 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 274, 300852 Thermus thermophilus, Thermus thermophilus HB8 Bacteria UP000000532 499547334, 55980647, 81600489, 55772060 WP_011228117.1, YP_143944.1 Q5SKG5 THIC_THET8 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 941261 fig|1316935.3.peg.1062, fig|300852.3.peg.634 433 435 yes 1892463 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 748654 Thioalkalivibrio sp. ALJ6 Bacteria 517704013 WP_018874221.1 626 629 yes 1892464 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 743722 Sphingobacterium sp. 21 Bacteria UP000007808 503430017, 326549565 ADZ77950.1 WP_013664678.1 fig|743722.3.peg.1484 622 622 yes 1892465 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 437507 Robiginitomaculum antarcticum Bacteria 516544102 WP_017931727.1 653 655 yes 1892466 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 119864, 717774 Marinomonas mediterranea, Marinomonas mediterranea MMB-1 Bacteria UP000001062 503426397, 326545933 ADZ91153.1 WP_013661058.1 fig|717774.3.peg.1961 640 649 yes 1892467 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2743, 1163748 Marinobacter hydrocarbonoclasticus, Marinobacter hydrocarbonoclasticus ATCC 49840 Bacteria UP000007884 504233449, 381338118 WP_014420551.1 fig|2743.3.peg.640 622 625 yes 1892468 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28091, 1051972 Neisseria weaveri, Neisseria weaveri ATCC 51223 Bacteria UP000004071 490413185, 343967996 EGV36234.1 WP_004285780.1 fig|1051972.3.peg.1048 621 624 yes 1892469 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 143393, 888727 Eubacterium sulci, Eubacterium sulci ATCC 35585 Bacteria UP000062530 736809621, 577036210 EUC78689.1 WP_034811405.1 436 437 yes 1892470 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 155863, 647113 Methanothermococcus okinawensis, Methanothermococcus okinawensis IH1 Archaea UP000009296 503632197, 334855611 AEH06087.1 WP_013866273.1 F8AMW4 F8AMW4_METOI 426 426 yes 1892471 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1202716, 858455 Rhodomicrobium sp. JA755, Rhodomicrobium sp. JA643 Bacteria UP000026572 739378322, 617476209 KAI94136.1 WP_037239174.1 263 266 no 1892472 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 886 Thermodesulfobacterium thermophilum Bacteria 551231477 WP_022855216.1 434 436 yes 1892473 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3068 Volvox carteri f. nagariensis Plants UP000001058 302843284, 300261571 EFJ45783.1 XP_002953184.1 567 642 yes 1892474 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 336261, 580340 Thermovirga lienii, Thermovirga lienii DSM 17291 Bacteria UP000053533, UP000005868 503929971, 355398130 AER67559.1 WP_014163965.1 fig|580340.6.peg.1947 425 425 yes 1892475 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59814, 1358411 Pantoea dispersa, Pantoea dispersa EGD-AAK13 Bacteria UP000016516 545152889, 542017753 ERH63564.1 WP_021508200.1 631 640 yes 1892476 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1131282 zeta proteobacterium SCGC AB-133-G06 Bacteria 517099577 WP_018288395.1 622 624 yes 1892477 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 152509 uncultured Bacteroidetes bacterium Environmental samples 374853032 600 603 yes 1892478 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1104682 Pseudomonas syringae pv. actinidiae ICMP 18804 Bacteria UP000015681 519225978 EPN07479.1 68 68 no 1892479 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262951 Ruminococcus sp. CAG:17 Environmental samples UP000018033 547241546, 524122756 WP_021977425.1 434 434 yes 1892480 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1048808 endosymbiont of Riftia pachyptila (vent Ph05) Bacteria UP000004491 344225354 EGV51715.1 fig|1048808.3.peg.1242 628 634 yes 1892481 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1248412 Xanthomonas sp. SHU308 Bacteria 516527087 WP_017914893.1 622 625 yes 1892482 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1231180, 391937 Nitratireductor pacificus, Nitratireductor sp. Pht-3B Bacteria UP000006786 495871839, 407300187 EKF19313.1 WP_008596418.1 fig|391937.3.peg.1913 597 605 yes 1892483 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1144318 Polaromonas sp. CF318 Bacteria UP000007275 495137947, 398100756 EJL90989.1 WP_007862755.1 fig|1144318.3.peg.231 638 639 yes 1892484 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316, 1123519 Pseudomonas stutzeri, Pseudomonas stutzeri DSM 10701 Bacteria UP000037382, UP000009004 504664243, 395807124 AFN76529.1 WP_014851345.1 fig|1123519.7.peg.451 626 626 yes 1892485 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469, 520709 Acinetobacter sp. NIPH 973 Bacteria 490837146, 479894100 ENU43938.1 WP_004699222.1 fig|651305.3.peg.700, fig|520709.3.peg.1401 621 625 yes 1892486 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 861, 457404 Fusobacterium ulcerans, Fusobacterium sp. 12_1B Bacteria UP000003233 495972485, 371964149 EHO81686.1 WP_008697064.1 fig|457404.3.peg.1550 425 425 yes 1892487 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 453230, 644282 Desulfarculus baarsii, Desulfarculus baarsii DSM 2075 Bacteria UP000009047 503023862, 301640075 ADK85397.1 WP_013258838.1 fig|644282.4.peg.2082 422 436 yes 1892488 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1512, 742740 Clostridium symbiosum, Clostridium symbiosum WAL-14163 Bacteria UP000002970 489596610, 323401301 EGA93651.1 WP_003501053.1 434 435 yes 1892489 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310816 Acinetobacter baumannii, Acinetobacter baumannii 1571545 Bacteria UP000028632, UP000027078 691122946, 630542107 KCY48688.1 WP_032041333.1 621 625 yes 1892490 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 767434 Frateuria aurantia DSM 6220 Bacteria UP000005234 379043877 AFC85933.1 fig|767434.3.peg.1482 594 608 yes 1892491 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36738, 1227456 Halococcus salifodinae, Halococcus salifodinae DSM 8989 Archaea 491185767, 445800316 EMA50671.1 WP_005044126.1 M0MYJ4 M0MYJ4_9EURY 451 483 yes 1892492 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1131813 Methylobacterium sp. 88A Bacteria 516689446 WP_018045537.1 627 635 yes 1892493 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28108, 1004788 Alteromonas macleodii, Alteromonas macleodii str. 'English Channel 673' Bacteria UP000031168, UP000006296 504788209, 407243624 AFT72810.1 WP_014975311.1 fig|1004788.3.peg.107 630 636 yes 1892494 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 662 515622692 WP_017055292.1 640 649 yes 1892495 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1280938 Pseudomonas aeruginosa, Pseudomonas aeruginosa B136-33 Bacteria UP000065817, UP000012183 505316647, 477553507 AGI84148.1 WP_015503749.1 fig|1280938.3.peg.5329 627 627 yes 1892496 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1267753 Salmonella enterica, Salmonella enterica subsp. enterica serovar Javiana str. CFSAN001992 Bacteria UP000054489, UP000011823 505219085, 451911080 AGF82886.1 WP_015406187.1 fig|1267753.3.peg.2723 626 631 yes 1892497 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 58290, 693661 Archaeoglobus veneficus, Archaeoglobus veneficus SNP6 Archaea UP000008136 503448831, 327316204 AEA46820.1 WP_013683492.1 F2KRX9 F2KRX9_ARCVS 427 428 yes 1892498 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1229204 alpha proteobacterium L41A Bacteria 516075885 WP_017506468.1 618 636 yes 1892499 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1404, 592022 Bacillus megaterium, Bacillus megaterium DSM319 Bacteria UP000036135, UP000002365 502846587, 294800274 ADF37340.1 WP_013081563.1 fig|592022.4.peg.382 589 589 yes 1892500 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35745, 662478 Haloferax denitrificans, Haloferax denitrificans ATCC 35960 Archaea 491107584, 445756828 EMA08184.1 WP_004967137.1 M0JJN0 M0JJN0_9EURY 435 465 yes 1892501 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 283734, 984892 Staphylococcus pseudintermedius, Staphylococcus pseudintermedius ED99 Bacteria UP000069715, UP000008642 504425776, 323463418 ADX75571.1 WP_014612878.1 fig|984892.3.peg.213 578 578 yes 1892502 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 561, 1182732, 1182697, 1182659, 1169331 Escherichia coli KTE159, Escherichia coli KTE96, Escherichia coli KTE52, Escherichia coli KTE11 Bacteria UP000014083, UP000014171, UP000014460, UP000010498 486146881, 508489268, 508422862, 508374788, 430893212 EOW58464.1, EOV93140.1, EOV46017.1, ELC15548.1 WP_001517538.1 fig|1169331.3.peg.3688, fig|1182697.3.peg.1394, fig|1182732.3.peg.3957 626 631 yes 1892503 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1105031 Clostridium sp. MSTE9 Bacteria UP000004073 496356279, 394755760 EJF38948.1 WP_009065455.1 fig|1105031.3.peg.2920 436 437 yes 1892504 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324, 1190567, 1183154 Stenotrophomonas maltophilia, Stenotrophomonas maltophilia EPM1, Stenotrophomonas maltophilia Ab55555 Bacteria UP000034806, UP000011772, UP000006955 491553351, 456734729, 401070528 EMF59499.1, EJP79042.1 WP_005410942.1 fig|1190567.3.peg.6700, fig|1183154.3.peg.3583 613 614 yes 1892505 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1116051 Escherichia coli, Escherichia coli P0299917.5 Bacteria UP000036210, UP000012409 485885784, 476969333 ENC56906.1 WP_001479693.1 fig|1116051.3.peg.4392 626 631 yes 1892506 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 365489 Dyadobacter beijingensis Bacteria 518783528 WP_019940817.1 625 625 yes 1892507 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 519989 Ectothiorhodospira sp. PHS-1 Bacteria UP000005314 496216686, 373940816 EHQ51361.1 WP_008930928.1 fig|519989.5.peg.326 626 629 yes 1892508 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 165694, 1094496 Bartonella schoenbuchensis, Bartonella schoenbuchensis m07a Bacteria UP000014242 498389601, 478417789 ENN91498.1 WP_010703522.1 fig|1094496.3.peg.384 603 612 yes 1892509 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1412874 uncultured archaeon A07HR60 Archaea UP000030679 558593351, 557617370 ESS10898.1 WP_023506062.1 V4Y7P2 V4Y7P2_9ARCH 458 497 yes 1892510 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1938, 1160705 Streptomyces viridochromogenes, Streptomyces viridochromogenes Tue57 Bacteria UP000037613, UP000011205 490097853, 443340402 ELS54614.1 WP_003999769.1 fig|1160705.3.peg.4385 592 594 yes 1892511 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 83333 Escherichia coli, Escherichia coli K-12 Bacteria UP000000625 UP000036210, UP000033060 414232 AAB95616.1 P30136 THIC_ECOLI Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 5581472, 3476182, 2463176, 18026, 7705075, 5499092, 5867766, 7677593, 2472283, 1242332 fig|749539.3.peg.3530, fig|1116099.3.peg.4576, fig|1227813.3.peg.3801, fig|1116153.3.peg.4946, fig|83333.1.peg.3907, fig|1116160.3.peg.4367, fig|1116001.3.peg.4940, fig|868191.3.peg.4664, fig|670892.3.peg.2262, fig|1116170.3.peg.4195, fig|868195.3.peg.4603, fig|913090.3.peg.4681, fig|913087.3.peg.1499, fig|1116029.3.peg.4630, fig|1116078.3.peg.4314, fig|1090926.6.peg.628, fig|868207.3.peg.4653, fig|1116133.3.peg.4573, fig|1116089.3.peg.4047, fig|1116184.3.peg.4275, fig|868208.3.peg.4541, fig|1116180.3.peg.4621, fig|869670.3.peg.87, fig|679206.4.peg.4376, fig|1116104.3.peg.4467, fig|1116162.3.peg.4404, fig|556266.3.peg.4543, fig|752788.3.peg.2338, fig|1116155.3.peg.4690, fig|1116034.3.peg.4584, fig|1116169.3.peg.4080, fig|1181768.3.peg.1469, fig|1116011.3.peg.4336, fig|1182729.3.peg.4469, fig|1169359.3.peg.302, fig|1005442.3.peg.4330, fig|1182703.3.peg.4797, fig|754084.3.peg.4239, fig|670888.3.peg.4760, fig|1182716.3.peg.21, fig|1116028.3.peg.4603, fig|868193.3.peg.5251, fig|868200.3.peg.4438, fig|1116178.3.peg.4644, fig|868210.3.peg.4828, fig|749538.3.peg.952, fig|868198.3.peg.4811, fig|595496.3.peg.3992, fig|1116031.3.peg.4540, fig|679202.3.peg.4706, fig|340185.3.peg.4780, fig|1169663.3.peg.876, fig|1116019.3.peg.4611, fig|766166.3.peg.4911, fig|1050617.5.peg.4836, fig|585034.4.peg.4094, fig|1182684.3.peg.4584, fig|1116092.3.peg.4618, fig|1182668.3.peg.4505, fig|1110693.3.peg.3420, fig|1068608.3.peg.3778, fig|1182700.3.peg.2943, fig|1116097.3.peg.4099, fig|868206.3.peg.4823, fig|1116094.3.peg.4074, fig|457401.3.peg.4737, fig|550687.3.peg.4701, fig|1116014.3.peg.4311, fig|1125649.3.peg.4699, fig|656372.3.peg.4744, fig|868196.3.peg.4336, fig|1078033.4.peg.1566, fig|879462.4.peg.4026, fig|868168.3.peg.4770, fig|868187.3.peg.4632, fig|1116045.3.peg.4384, fig|1116157.3.peg.4706, fig|595495.4.peg.4766, fig|1169352.3.peg.4934, fig|1167694.3.peg.4585, fig|869687.4.peg.3660, fig|1116079.3.peg.4540, fig|1116168.3.peg.4260, fig|1181743.3.peg.224, fig|1169379.3.peg.4479, fig|331112.3.peg.3943, fig|868162.3.peg.4786, fig|1116102.3.peg.4371, fig|1144303.3.peg.4303, fig|869688.4.peg.2378, fig|1116026.3.peg.4370, fig|679205.4.peg.723, fig|1116093.3.peg.4650, fig|1116017.3.peg.4327, fig|656408.3.peg.4481, fig|1116129.3.peg.4961, fig|1116134.3.peg.4597, fig|1169396.3.peg.4415, fig|754088.3.peg.4807, fig|670903.3.peg.4603, fig|1181767.3.peg.4641, fig|1116105.3.peg.4586, fig|316385.7.peg.4211, fig|1137135.3.peg.728, fig|749533.3.peg.5010, fig|1116140.3.peg.4677, fig|868190.3.peg.4488, fig|754090.3.peg.4767, fig|1116121.3.peg.4518, fig|868160.3.peg.4657, fig|511145.12.peg.4108, fig|1116077.3.peg.4640, fig|868203.3.peg.4711, fig|1182728.3.peg.2093, fig|1116120.3.peg.4679, fig|1116172.3.peg.4673, fig|1116161.3.peg.4549, fig|869691.3.peg.4927, fig|1116187.3.peg.4666, fig|1116076.3.peg.4383, fig|1116021.3.peg.4410, fig|1116095.3.peg.4648, fig|1182715.3.peg.5076, fig|869679.3.peg.1310, fig|696406.3.peg.4724, fig|1182678.3.peg.5019, fig|1116073.3.peg.4480, fig|1116005.3.peg.4023, fig|1005564.3.peg.4537, fig|566546.3.peg.4747, fig|868188.3.peg.4808, fig|1078030.10.peg.1896, fig|1101440.4.peg.4377, fig|1005567.3.peg.4149, fig|1182706.3.peg.232, fig|1116114.3.peg.4117, fig|868169.3.peg.4442, fig|749540.3.peg.2258, fig|1125650.3.peg.3787, fig|1246623.3.peg.46, fig|344601.3.peg.4299, fig|754081.3.peg.4441, fig|316407.3.peg.3160, fig|1116000.3.peg.4451, fig|1182658.3.peg.5135, fig|1116107.3.peg.3780, fig|868184.3.peg.4629, fig|585395.4.peg.4970, fig|868165.3.peg.4788, fig|475609.3.peg.4191, fig|868163.3.peg.4680, fig|656414.3.peg.4533, fig|1116188.3.peg.4329, fig|1125646.3.peg.4679, fig|1116090.3.peg.4636, fig|1227814.3.peg.4001, fig|1125648.3.peg.3830, fig|1090930.3.peg.4119, fig|1116156.3.peg.4617, fig|1182702.3.peg.224, fig|1116167.3.peg.4573, fig|1116003.3.peg.4464, fig|1116166.3.peg.4281, fig|1090929.3.peg.3451, fig|1115999.3.peg.4478, fig|670890.3.peg.922, fig|1169863.3.peg.4793, fig|1115997.3.peg.5163, fig|1169388.3.peg.4088, fig|1116165.3.peg.4624, fig|869680.3.peg.2701, fig|868192.3.peg.5187, fig|1115998.3.peg.293, fig|868202.3.peg.4783, fig|1116176.3.peg.4618, fig|1116173.3.peg.4261, fig|1116109.3.peg.4525, fig|868186.3.peg.4612, fig|656405.3.peg.4957, fig|1116174.3.peg.4257, fig|1169333.3.peg.4605, fig|670896.3.peg.4599, fig|868204.3.peg.4634, fig|1116018.3.peg.4408, fig|1165941.3.peg.4282, fig|1116074.3.peg.4277, fig|1005562.3.peg.4428, fig|1116037.3.peg.3577, fig|868161.3.peg.4927, fig|1116122.3.peg.4873, fig|656413.3.peg.3092, fig|754087.3.peg.4669, fig|868167.3.peg.4577, fig|749548.3.peg.1711, fig|869677.3.peg.3418, fig|1116177.3.peg.4994, fig|1274814.3.peg.147, fig|754078.3.peg.4369, fig|670894.3.peg.2444, fig|1005464.3.peg.4172, fig|536056.3.peg.4252, fig|1116027.3.peg.4549, fig|1005462.3.peg.4201, fig|1116020.3.peg.4631, fig|1116004.3.peg.4391, fig|1169397.3.peg.4264, fig|1116101.3.peg.4005, fig|1125651.3.peg.4838, fig|1116191.3.peg.4272, fig|457400.3.peg.2094, fig|868194.3.peg.4903, fig|868199.3.peg.4414, fig|868197.3.peg.4093, fig|1125636.3.peg.4531, fig|868164.3.peg.4557, fig|562.1188.peg.4252, fig|869694.3.peg.328, fig|869671.3.peg.3514, fig|1182730.3.peg.287, fig|868189.3.peg.4868, fig|1116106.3.peg.3918, fig|1116164.3.peg.4598, fig|1182738.3.peg.21, fig|749544.3.peg.686, fig|869675.3.peg.5103, fig|1182688.3.peg.222, fig|1169320.3.peg.4950, fig|1116175.3.peg.4600, fig|1116035.3.peg.4572, fig|869690.3.peg.1242, fig|1165940.3.peg.4453, fig|945434.3.peg.3036, fig|409438.11.peg.4461, fig|1116163.3.peg.4442, fig|1181744.3.peg.5140, fig|868209.3.peg.4478, fig|1116012.3.peg.4723, fig|1182733.3.peg.1578, fig|1116181.3.peg.4718 622 627 yes 1892512 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2246, 309800 Haloferax volcanii, Haloferax volcanii DS2 Archaea UP000011532 502800587, 292656282, 291372304 ADE04531.1 WP_013035563.1, YP_003536179.1 D4GV87 D4GV87_HALVD 10160611 454 482 yes 1892513 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 984235 Salmonella enterica subsp. enterica serovar Gaminara str. ATCC BAA-711 Bacteria UP000017435 554292674 ESH28897.1 626 631 yes 1892514 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33038, 1073375, 658082, 1263106 Ruminococcus gnavus, Lachnospiraceae bacterium CC55_001C, Lachnospiraceae bacterium 2_1_58FAA, Ruminococcus gnavus CAG:126 Bacteria, Environmental samples UP000018690, UP000004820, UP000018114 496539084, 564720748, 336016311, 524200313 ETD20802.1, EGN46098.1 WP_009245232.1 fig|658082.3.peg.2355 434 434 yes 1892515 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84112, 479437 Eggerthella lenta, Eggerthella lenta DSM 2243 Bacteria UP000001377 506241158, 257475707 ACV56027.1 WP_015760933.1 fig|479437.4.peg.645 440 441 yes 1892516 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1238203 Vibrio parahaemolyticus, Vibrio parahaemolyticus 970107 Bacteria UP000028114, UP000018828 646368870, 655683311, 655648079, 567325071 KED76457.1, KED45769.1, ETJ86114.1 WP_025510133.1 640 646 yes 1892517 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 698952 Gardnerella vaginalis 0288E Bacteria UP000003609 388053814 EIK76778.1 fig|698952.3.peg.1144 609 881 yes 1892518 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47886 Pseudomonas luteola Bacteria 518193821 WP_019364029.1 625 625 yes 1892519 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 544 547 yes 1892520 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 359407 519027238 WP_020183113.1 624 627 yes 1892521 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 675816 Vibrio orientalis CIP 102891 Bacteria UP000003515 260939624 EEX95609.1 641 686 yes 1892522 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553, 1095774 Pantoea ananatis, Pantoea ananatis PA13 Bacteria UP000029850, UP000005872 504419862, 354990418 AER34542.1 WP_014606964.1 fig|1095774.3.peg.4260 632 640 yes 1892523 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 212663 Vibrio tasmaniensis Bacteria 515676020 WP_017108620.1 640 649 yes 1892524 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543, 550, 1410031, 1619237, 1619240, 1619241, 1619242, 1619251, 1439331, 1329835, 1329811, 1329814, 1329818, 1329821, 1329820, 1329837, 1329830, 1329817 Enterobacter cloacae, Enterobacter cloacae MRSN 11248, Enterobacter sp. 35014, Enterobacter sp. 35025, Enterobacter sp. 35032, Enterobacter sp. 35030, Enterobacter sp. 35683, Lelliottia amnigena CHS 78, Enterobacter sp. BWH 27, Enterobacter sp. MGH 2, Enterobacter sp. MGH 5, Enterobacter sp. MGH 9, Enterobacter sp. MGH 12, Enterobacter sp. MGH 11, Enterobacter sp. BWH 39, Enterobacter sp. MGH 26, Enterobacter sp. MGH 8 Bacteria UP000036177, UP000034848, UP000033579, UP000033395, UP000033557, UP000033478, UP000033343, UP000027321, UP000024177, UP000022767, UP000021512, UP000020383, UP000023085, UP000022774, UP000021813, UP000017609, UP000017163 550713819, 838665260, 816080469, 771276106, 771262859, 771251377, 771250774, 771154907, 636476031, 612324331, 578343072, 578332326, 578314218, 578303272, 578302202, 578270179, 555171716, 550210911 KLW49025.1, KKJ28075.1, KJO11812.1, KJN98913.1, KJN87835.1, KJN87249.1, KJN12935.1, KDM52446.1, EZR16665.1, EUN02144.1, EUM91522.1, EUM73677.1, EUM62852.1, EUM61796.1, EUM30107.1, ESN14334.1, ERP01263.1 WP_022646708.1 626 631 yes 1892525 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1757, 589861 Thermoanaerobacter ethanolicus, Thermoanaerobacter ethanolicus CCSD1 Bacteria UP000005690 489964237, 256749612 EEU62639.1 WP_003867481.1 fig|589861.3.peg.958 431 432 yes 1892526 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1055487, 666681 Methylotenera versatilis, Methylotenera sp. 301 Bacteria UP000000383 502914422, 297259248 ADI31093.1 WP_013149398.1 fig|666681.3.peg.2763 625 631 yes 1892527 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 258591, 1121939 Halomonas anticariensis, Halomonas anticariensis DSM 16096 Bacteria UP000014463 512440832, 511274550 EPC02683.1 WP_016416619.1 628 629 yes 1892528 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644, 1354302 Aeromonas hydrophila, Aeromonas hydrophila 4AK4 Bacteria UP000032249, UP000018847 644509502, 569546242 AHE47863.1 WP_025325472.1 645 664 yes 1892529 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 930772 Salmonella enterica, Salmonella enterica subsp. enterica serovar Senftenberg str. ATCC 43845 Bacteria UP000054489, UP000017496 554960530, 554116283 ESF57410.1 WP_023205250.1 626 631 yes 1892530 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 662 680 yes 1892531 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1485, 1509, 1408284 Clostridium sporogenes, Clostridium botulinum Prevot_594 Bacteria UP000051171, UP000031265 696525618, 827567305, 808211679, 745830662, 630822691 AKJ90854.1, AKC63702.1, AJD32089.1, KCZ67400.1 WP_033060878.1 437 437 yes 1892532 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1522671, 1388758 Dehalococcoides sp. UCH007, Dehalococcoides mccartyi GY50 Bacteria UP000033281, UP000018576 561136321, 559771928, 757804033 AHB13440.1 WP_023652218.1 430 431 yes 1892533 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 58180, 207559 Desulfovibrio alaskensis, Desulfovibrio desulfuricans subsp. desulfuricans str. G20 Bacteria UP000002710 499686890, 78219128 ABB38477.1 WP_011367624.1 fig|207559.3.peg.1473 419 429 no 1892534 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375288, 658661 Parabacteroides sp. D25 Bacteria UP000006270 496574811, 409236281 EKN29088.1 WP_009275929.1 fig|658661.3.peg.2269, fig|457388.5.peg.1285 565 565 yes 1892535 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286 517927483 WP_019097691.1 625 626 yes 1892536 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54736, 1197719, 218493 Salmonella bongori, Salmonella bongori Sbon_167, Salmonella bongori 12149 Bacteria UP000015042, UP000000289 446030429, 526129286, 339514912 AGR61359.1 WP_000108284.1 fig|218493.3.peg.3905, fig|12149.1.peg.4130 626 631 yes 1892537 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470, 1310864 Acinetobacter baumannii, Acinetobacter baumannii 24845_10 Bacteria UP000028632, UP000023373 691000680, 594005684 EXU57564.1 WP_031968082.1 621 625 yes 1892538 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543, 1659714, 1169322 Enterobacter sp. GN02600, Citrobacter sp. KTE151 Bacteria UP000036047, UP000014006 507084565, 829325527, 500603879 KLQ18117.1, EOQ44753.1 WP_016155310.1 fig|1169322.3.peg.4876, fig|670484.3.peg.4654 626 632 yes 1892539 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 551936 Bradyrhizobium sp. STM 3809 Bacteria UP000004098 496247082, 365338114 WP_008960467.1 fig|551936.3.peg.404 622 633 yes 1892540 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 291645, 997884 Bacteroides nordii, Bacteroides nordii CL02T12C05 Bacteria UP000003089 494750445, 392656018 EIY49659.1 WP_007485853.1 fig|997884.3.peg.2832 564 564 yes 1892541 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 202951, 1120925 Acinetobacter bouvetii, Acinetobacter bouvetii DSM 14964 = CIP 107468 Bacteria UP000018460 491154945, 480041893 ENV81315.1 WP_005013336.1 fig|1120925.3.peg.3297 626 631 yes 1892542 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397527 Alcanivorax sp. P2S70 Bacteria UP000017116 551585932, 550666834 ERP92533.1 WP_022984144.1 624 628 yes 1892543 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1446768 Escherichia coli, Escherichia coli O91:NM str. 2009C-3745 Bacteria UP000036210, UP000024038 693180375, 607752007 EZE33446.1 WP_032308801.1 626 631 yes 1892544 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 766154 Shigella flexneri 1235-66 Bacteria 391306801 EIQ64552.1 fig|766154.3.peg.7726 442 444 yes 1892545 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 208962 Escherichia albertii Bacteria UP000066054 446228419 WP_000306274.1 571 573 yes 1892546 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 145263, 79929 Methanothermobacter marburgensis, Methanothermobacter marburgensis str. Marburg Archaea UP000000345 503059991, 304313904, 302587363 ADL57738.1 WP_013294967.1, YP_003849051.1 D9PU40 D9PU40_METTM 433 433 yes 1892547 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 886559 Geobacillus sp. WSUCF1 Bacteria UP000014961 523425903 EPR26249.1 449 530 no 1892548 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 859, 1226633 Fusobacterium necrophorum, Fusobacterium necrophorum subsp. funduliforme B35 Bacteria UP000031184 759890666, 598623918 EYD68485.1 WP_043577290.1 433 433 yes 1892549 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29449, 347834 Rhizobium etli, Rhizobium etli CFN 42 Bacteria UP000001936 695262081, 695198119, 2627326 AAC45972.1 WP_032489040.1, YP_009075177.1 Q2K206 THIC_RHIEC Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 1268730 601 610 yes 1892550 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 518635 Bifidobacterium angulatum DSM 20098 Bacteria UP000035066 229785122 EEP21236.1 fig|518635.5.peg.662 631 847 yes 1892551 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29549, 762570 Rhodothermus marinus, Rhodothermus marinus SG0.5JP17-172 Bacteria UP000001280 503831819, 345111194 AEN72026.1 WP_014065813.1 fig|762570.4.peg.74 626 627 yes 1892552 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 553611, 1248232 Photobacterium leiognathi, Photobacterium leiognathi lrivu.4.1 Bacteria UP000032558, UP000030675 565848451, 531078563 WP_023931266.1 637 640 yes 1892553 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 203275, 1307833, 1307832 Tannerella forsythia ATCC 43037, Tannerella forsythia KS16, Tannerella forsythia 3313 Bacteria UP000005436, UP000055820, UP000064745 363406754, 806921046, 806918353 AEW20440.1 fig|203275.8.peg.1845 511 513 no 1892554 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1124956 Salmonella enterica, Salmonella enterica subsp. enterica serovar Minnesota str. ATCC 49284 Bacteria UP000054489, UP000017584 555230015, 554187074 ESG25975.1 WP_023217496.1 626 631 yes 1892555 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1077976 Gordonia polyisoprenivorans NBRC 16320 Bacteria UP000005812 359313391 fig|1077976.3.peg.4854 451 456 yes 1892556 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29371, 1195236 Clostridium termitidis, Clostridium termitidis CT1112 Bacteria UP000014155 490766073, 474476491 EMS70433.1 WP_004628307.1 fig|1195236.3.peg.4051 436 436 yes 1892557 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 274, 762633 Thermus thermophilus, Thermus thermophilus SG0.5JP17-16 Bacteria UP000009233 504322981, 333966336 AEG33101.1 WP_014510083.1 fig|762633.3.peg.681 432 435 yes 1892558 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 157268, 556267 Helicobacter winghamensis, Helicobacter winghamensis ATCC BAA-430 Bacteria UP000004660 493855580, 229375881 EEO25972.1 WP_006802458.1 fig|556267.4.peg.1065 447 448 yes 1892559 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 997347 Fusobacterium nucleatum subsp. animalis ATCC 51191 Bacteria UP000005392 339891991 EGQ80897.1 fig|997347.4.peg.73 433 433 yes 1892560 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 911092, 1388761 Caldanaerobacter subterraneus, Caldanaerobacter subterraneus subsp. yonseiensis KB-1 Bacteria UP000053343, UP000016856 550173659, 548793660 ERM91950.1 WP_022587999.1 431 432 yes 1892561 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59538 Pantholops hodgsonii Mammals 556756145 XP_005973423.1 609 621 yes 1892562 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1118963 Arthrobacter sp. Rue61a Bacteria UP000003736 504734982, 403230083 AFR29505.1 WP_014922084.1 fig|1118963.3.peg.2688 596 678 yes 1892563 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 263378, 1123237 Salipiger mucosus, Salipiger mucosus DSM 16094 Bacteria UP000015347 518886892, 528099683 EPX81388.1 WP_020042767.1 597 600 yes 1892564 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1217709 Acinetobacter sp. NIPH 713 Bacteria UP000023774 491311006, 480151451 ENW88430.1 WP_005168985.1 fig|1217709.3.peg.324 627 631 yes 1892565 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47951 Vibrio cyclitrophicus Bacteria 515167715 WP_016796226.1 640 649 yes 1892566 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59538 Pantholops hodgsonii Mammals 556764131 XP_005977342.1 587 653 yes 1892567 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 1395579, 1395580 Enterobacter sp. DC3, Enterobacter sp. DC4 Bacteria UP000019280, UP000019283 695720961, 584253484, 584246862 EWG72886.1, EWG66305.1 WP_032648408.1 626 631 yes 1892568 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 885275, 885276, 199310 Escherichia coli str. 'clone D i14', Escherichia coli str. 'clone D i2', Escherichia coli CFT073 Bacteria UP000005864, UP000005865, UP000001410 355427781, 355422861, 26111196 AER91977.1, AER87058.1, AAN83379.1 Q8FB77 THIC_ECOL6 Phosphomethylpyrimidine synthase {ECO:0000255|HAMAP-Rule:MF_00089} 306687 fig|1322345.3.peg.1378, fig|1169398.3.peg.4116, fig|1182674.3.peg.426, fig|525281.3.peg.4730, fig|749528.3.peg.1798, fig|1169393.3.peg.4270, fig|1258580.3.peg.2206, fig|316435.3.peg.3938, fig|1181769.3.peg.20, fig|749546.3.peg.1675, fig|1182670.3.peg.145, fig|1258567.3.peg.2171, fig|1169400.3.peg.4441, fig|1181760.3.peg.415, fig|1182667.3.peg.4830, fig|749541.3.peg.1029, fig|1169370.3.peg.4078, fig|1181747.3.peg.20, fig|1181734.3.peg.4858, fig|199310.4.peg.4650, fig|1169395.3.peg.4276, fig|1181766.3.peg.4122, fig|1169381.3.peg.4447, fig|1181755.3.peg.2186, fig|1163386.3.peg.1986, fig|1169387.3.peg.4309, fig|1169356.3.peg.5012, fig|1182692.3.peg.4878, fig|885276.3.peg.4348, fig|1181776.3.peg.4783, fig|1169371.3.peg.4324, fig|1182721.3.peg.4707, fig|199310.1.peg.4848, fig|1181772.3.peg.4526, fig|655817.3.peg.4700, fig|1181764.3.peg.305, fig|885275.3.peg.4343, fig|1182660.3.peg.5053, fig|1181733.3.peg.19 626 635 yes 1892569 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 720605 Halomonas sp. AAD4 Bacteria 515332244 WP_016856078.1 641 643 yes 1892570 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1281094 Escherichia coli, Escherichia coli HVH 161 (4-3119890) Bacteria UP000036210, UP000015994 545237006, 535125543 EQS71357.1 WP_021536169.1 626 631 yes 1892571 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 859, 1161424 Fusobacterium necrophorum, Fusobacterium necrophorum subsp. funduliforme Fnf 1007 Bacteria UP000003120 492774335, 402269302 EJU18640.1 WP_005960486.1 fig|1161424.3.peg.426 433 433 yes 1892572 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 984307 Burkholderia kururiensis Bacteria 516388190 WP_017777866.1 642 643 yes 1892573 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1574141, 1404258, 936156, 1313 Bacillus sp. YP1, Bacillus subtilis subsp. subtilis str. OH 131.1, Bacillus subtilis BSn5, Streptococcus pneumoniae Bacteria UP000032021, UP000027304, UP000007474, UP000029709 505916041, 758179635, 655529993, 320020876, 811397261 AJO57514.1, AIC97434.1, ADV95862.1 WP_015715545.1 fig|936156.3.peg.3317 590 590 yes 1892574 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1262746 Bacteroides sp. CAG:661 Environmental samples UP000018335 547288532, 524178631 WP_022021518.1 570 575 yes 1892575 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1121100 Bacteroides pyogenes DSM 20611 Bacteria UP000018842 567760410 65 65 no 1892576 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40545, 742821 Sutterella wadsworthensis, Sutterella wadsworthensis 3_1_45B Bacteria UP000005620 491573156, 319804881 EFW01735.1 WP_005430737.1 480 564 yes 1892577 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 999141 Halomonas sp. TD01 Bacteria UP000004744 497408208, 338765657 EGP20592.1 WP_009722406.1 636 648 yes 1892578 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 280236 Nocardiopsis gilva Bacteria 516213328 WP_017617291.1 552 554 yes 1892579 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1731, 1286171 Eubacterium acidaminophilum, Eubacterium acidaminophilum DSM 3953 Bacteria UP000019591 645065189, 595613750 AHM57395.1 WP_025436320.1 437 437 yes 1892580 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 457430 Streptomyces roseosporus NRRL 11379 Bacteria UP000027349 586915829 EWS93035.1 554 555 yes 1892581 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 164400, 1234382 Thauera phenylacetica, Thauera phenylacetica B4P Bacteria UP000013047 490506782, 479307534 ENO95634.1 WP_004372828.1 639 639 yes 1892582 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1136179 Rhodococcus erythropolis CCM2595 Bacteria UP000015928 532221248 AGT91281.1 534 543 yes 1892583 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83618 518227972 WP_019398180.1 622 625 yes 1892584 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 1399146 Enterobacter cloacae, Enterobacter cloacae S611 Bacteria UP000036177, UP000017834 558085240, 557855075 ESS58935.1 WP_023479385.1 626 631 yes 1892585 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1049766 Leptospira borgpetersenii serovar Javanica str. MK146 Bacteria UP000012134 464254776 EMN59086.1 229 235 no 1892586 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287074 Mesorhizobium sp. L103C105A0 Bacteria UP000020702 564009152, 563247654 ESZ70052.1 WP_023835288.1 596 611 yes 1892587 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408 Bacillus pumilus Bacteria UP000037521 643379317, 594024275 AHL72279.1 WP_025207713.1 586 586 yes 1892588 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1638779, 1262738 Bacteroides sp. UNK.MGS-13, Bacteroides sp. CAG:20 Bacteria, Environmental samples UP000018221 546770463, 524012301 WP_021892503.1 567 567 yes 1892589 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287270 Mesorhizobium sp. LNJC386A00 Bacteria UP000021957 563543410, 563105025 ESY29515.1 WP_023749415.1 596 611 yes 1892590 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 456442 Candidatus Methanoregula boonei 6A8 Archaea UP000002408 153998145 ABS54568.1 A7I4A7 A7I4A7_METB6 fig|456442.10.peg.44 413 425 no 1892591 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286, 69328 Pseudomonas sp. VLB120 Bacteria UP000017756 557301426, 556072991 AGZ33324.1 WP_023378431.1 627 628 yes 1892592 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 260742 Streptomyces sp. SS Bacteria 515809684 WP_017240437.1 592 594 yes 1892593 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324, 868597 Stenotrophomonas maltophilia, Burkholderia sp. JV3 Bacteria UP000034806, UP000000700 503804404, 343780122 AEM52675.1 WP_014038398.1 fig|868597.3.peg.3383 613 614 yes 1892594 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1210045 Streptomyces sp. AA0539 Bacteria 518262019 WP_019432227.1 523 528 yes 1892595 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 13689 Sphingomonas paucimobilis Bacteria UP000023992 739627439, 612114049 EZP72124.1 WP_037483836.1 611 615 yes 1892596 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 187400 Paracoccus zeaxanthinifaciens Bacteria 550957848 WP_022706194.1 591 592 yes 1892597 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46234 Anabaena sp. 90 Bacteria UP000010101 504891127, 413968976 AFW93065.1 WP_015078229.1 fig|46234.3.peg.299 455 457 yes 1892598 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913073 Salmonella enterica subsp. enterica serovar Hvittingfoss str. A4-620 Bacteria UP000004517 353583588 EHC43906.1 fig|913073.3.peg.4407 87 89 no 1892599 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 583357, 583358 Thermoanaerobacter mathranii, Thermoanaerobacter mathranii subsp. mathranii str. A3 Bacteria UP000002064 502915763, 296843002 ADH61518.1 WP_013150739.1 fig|583358.3.peg.707 431 432 yes 1892600 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 578833, 1619235, 316, 644801, 32042 Pseudomonas sp. BICA1-14, Pseudomonas stutzeri, Pseudomonas stutzeri RCH2, Pseudomonas stutzeri ATCC 14405 = CCUG 16156 Bacteria UP000036016, UP000037382, UP000010820, UP000006312 489378496, 780913252, 763445094, 431823967, 379066657 KJS80840.1, KIZ38422.1, AGA85084.1, EHY79400.1 WP_003285206.1 fig|644801.3.peg.475, fig|32042.3.peg.3655 626 626 yes 1892601 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469586, 1263054 Bacteroides sp. 1_1_6, Bacteroides thetaiotaomicron CAG:40 Bacteria, Environmental samples UP000003591, UP000018192 496041027, 251842595, 524776752 EES70675.1 WP_008765534.1 fig|469586.3.peg.879 565 565 yes 1892602 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 110321 Sinorhizobium medicae Bacteria 517007264 WP_018210039.1 597 610 yes 1892603 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53246, 234831 Pseudoalteromonas sp. SM9913 Bacteria UP000007933 503229296, 315013986 ADT67324.1 WP_013463957.1 fig|234831.3.peg.994, fig|1175295.3.peg.3012 645 650 yes 1892604 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28182, 1193055 Leptospira noguchii, Leptospira noguchii str. Hook Bacteria UP000018513 490590833, 474498389 EMS86170.1 WP_004455853.1 fig|1193055.3.peg.2237 443 496 yes 1892605 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4006 Linum usitatissimum Plants 395146505 AFN53660.1 557 952 yes 1892606 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444133 Escherichia coli, Escherichia coli 1-176-05_S3_C1 Bacteria UP000036210, UP000021352 693071054, 598673372 EYD81490.1 WP_032235225.1 626 631 yes 1892607 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65741, 1301098 Pseudomonas knackmussii, Pseudomonas knackmussii B13 Bacteria UP000025241 759535790, 631782121 WP_043255804.1 625 626 yes 1892608 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 640 647 yes 1892609 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 359359 Smaragdicoccus niigatensis Bacteria 516906236 WP_018158671.1 547 550 yes 2136376 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29320 Arthrobacter nicotinovorans Bacteria 651444430 WP_026540260.1 593 624 yes 2136377 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 926571 Nitrososphaera viennensis EN76 Archaea UP000027093 647811180 AIC14881.1 A0A060HMT3 A0A060HMT3_9ARCH 458 461 yes 2136378 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 653800724 WP_027688385.1 598 605 yes 2136379 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 281361 Flavobacterium denitrificans Bacteria 652331386 WP_026728627.1 607 607 yes 2136380 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 613 621 yes 2136381 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 47157 Desulfovibrio bastinii Bacteria 652926173 WP_027179953.1 419 421 no 2136382 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1033 640480357 WP_024920391.1 fig|502800.3.peg.3985, fig|545431.3.peg.1128, fig|1325475.3.peg.808, fig|649715.3.peg.111, fig|349746.3.peg.2292, fig|386656.4.peg.3425, fig|229193.1.peg.3062, fig|1324587.3.peg.2498, fig|502801.6.peg.187, fig|273123.1.peg.297, fig|1291550.3.peg.2350, fig|1324608.3.peg.3365, fig|1286085.3.peg.320, fig|349747.3.peg.2364 634 643 yes 2136383 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 614, 1460083 Serratia liquefaciens, Serratia liquefaciens FK01 Bacteria UP000033102, UP000054386 764988212, 641641650 WP_044554718.1 633 647 yes 2136384 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 454601 Maritalea myrionectae Bacteria 654341295 WP_027834745.1 593 599 yes 2136385 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 405746 Phaeobacter daeponensis Bacteria 652991034 WP_027243513.1 596 604 yes 2136386 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1381123 Aliihoeflea sp. 2WW Bacteria 639289211 WP_024586064.1 598 602 yes 2136387 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 338191 648398202 WP_026089953.1 442 442 yes 2136388 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 514835964 WP_016583221.1 442 453 yes 2136389 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1232438 Clostridiales bacterium VE202-01 Bacteria 639694217 WP_024720954.1 fig|331271.3.peg.2125, fig|331272.3.peg.3158 435 435 yes 2136390 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287 Pseudomonas aeruginosa Bacteria UP000065817 640474847 WP_024915326.1 fig|369723.3.peg.2550, fig|1169195.3.peg.3889 627 627 yes 2136391 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1101191 Methylobacterium sp. 10 Bacteria 652917793 WP_027171669.1 624 635 yes 2136392 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|349161.4.peg.675 631 641 yes 2136393 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 391738, 1385515 Lysobacter defluvii, Lysobacter defluvii IMMIB APB-9 Bacteria UP000030003 652749329, 700656420 KGO98669.1 WP_027070100.1 624 625 yes 2136394 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444193 Escherichia coli, Escherichia coli 3-105-05_S3_C3 Bacteria UP000036210, UP000028054 693088142, 650086634 KDU08331.1 WP_032247940.1 626 631 yes 2136395 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1276756 Acidovorax sp. JHL-9 Bacteria 651308997 WP_026436626.1 624 630 yes 2136396 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 544645 Butyricimonas virosa Bacteria 652949270 WP_027202684.1 582 582 yes 2136397 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1469245 Thioalkalivibrio sp. HK1 Bacteria 647349376 WP_025769709.1 621 626 yes 2136398 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646379487 WP_025518821.1 640 646 yes 2136399 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1993 Actinomadura madurae Bacteria 640498051 WP_024936017.1 fig|319224.13.peg.832 570 574 yes 2136400 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1531 Clostridium clostridioforme Bacteria 653638265 WP_027641414.1 434 435 yes 2136401 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 173 Leptospira interrogans Bacteria UP000037872 642965647 WP_025178710.1 173 173 no 2136402 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1492738 Flavobacterium sp. EM1321 Bacteria UP000027064 737687874, 640830635 KDN56793.1 WP_035656922.1 fig|402882.10.peg.2580 607 607 yes 2136403 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 64974 Marinospirillum minutulum Bacteria 654355681 WP_027848139.1 629 638 yes 2136404 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 639468137 WP_024642244.1 627 629 yes 2136405 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1216961 Aeromonas sp. 159 Bacteria 648253761 WP_026034910.1 605 615 yes 2136406 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935837 Bacillus sp. J37 Bacteria 651520140 WP_026559984.1 583 583 yes 2136407 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406 Paenibacillus polymyxa Bacteria UP000031922 647276318 WP_025722152.1 395 395 yes 2136408 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1071679 Burkholderia sp. enrichment culture clone R27 Environmental samples UP000027439 737999615, 646764746 KDR36617.1 WP_035961204.1 642 643 yes 2136409 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280686 Butyrivibrio sp. MC2013 Bacteria 651396190 WP_026507892.1 434 435 yes 2136410 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645917964 WP_025471949.1 420 431 yes 2136411 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 640506228 WP_024942689.1 fig|399549.6.peg.322 662 680 yes 2136412 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 610245 Asaia sp. T-153 Bacteria 647609847 WP_025885544.1 613 623 yes 2136413 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645921317 WP_025475302.1 414 425 yes 2136414 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471530 Prochlorococcus sp. scB245a_521N5 Bacteria 647719928 WP_025971360.1 238 238 no 2136415 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 57666 Sulfurospirillum arcachonense Bacteria 640519991 WP_024954398.1 fig|114615.3.peg.2242 447 448 yes 2136416 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|204773.3.peg.847 640 640 yes 2136417 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35839 Holophaga foetida Bacteria 491173594 WP_005031960.1 605 610 yes 2136418 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1418 Bacillus mannanilyticus Bacteria 640599836 WP_025028465.1 fig|349106.5.peg.1697 592 592 yes 2136419 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28174 Vibrio ordalii Bacteria 648247658 WP_026028807.1 640 649 yes 2136420 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 41791 Desulfovibrio acrylicus Bacteria 653112628 WP_027362248.1 419 429 no 2136421 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 228 Pseudoalteromonas haloplanktis Bacteria 639338003 WP_024600334.1 fig|9606.3.peg.19226 645 650 yes 2136422 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646919150 WP_025613076.1 640 646 yes 2136423 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83615 Luteimonas mephitis Bacteria 652764084 WP_027079062.1 623 625 yes 2136424 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646419978, 778223321 KJR18280.1 WP_025527230.1 640 646 yes 2136425 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1387312 Methylophilus sp. OH31 Bacteria 640491247 WP_024930288.1 fig|399742.10.peg.1205 624 626 yes 2136426 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 990370 Pseudogulbenkiania sp. MAI-1 Bacteria 635656699 WP_024303566.1 635 636 yes 2136427 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33038 Ruminococcus gnavus Bacteria 640289071 WP_024852770.1 434 434 yes 2136428 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1460649 Geomicrobium sp. JCM 19055 Bacteria UP000027034 636486141 588 588 yes 2136429 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 196180 Anoxybacillus kamchatkensis Bacteria 648230430 WP_026011579.1 560 561 yes 2136430 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1244513 Luteimonas sp. enrichment culture clone HB2 Environmental samples 640398339 WP_024891420.1 623 629 yes 2136431 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1134055 Verrucomicrobium sp. 3C Bacteria 648503921 WP_026195672.1 622 622 yes 2136432 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 412438 Chryseobacterium daeguense Bacteria 653129470 WP_027378859.1 603 603 yes 2136433 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 990068 Lebetimonas sp. JH292 Bacteria 640072399 WP_024789311.1 fig|272943.3.peg.2538 461 461 yes 2136434 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 996925 Mastigocoleus testarum Bacteria 654350360 WP_027843631.1 611 626 yes 2136435 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29347 Clostridium scindens Bacteria 647129734 WP_025645541.1 434 434 yes 2136436 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444266, 1444168 Escherichia coli, Escherichia coli 2-427-07_S4_C3, Escherichia coli 3-267-03_S3_C2 Bacteria UP000036210, UP000027642, UP000028085 693019767, 658700854, 650071137 KEJ43351.1, KDT93136.1 WP_032198258.1 626 631 yes 2136437 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449069 Rhodococcus sp. UNC363MFTsu5.1 Bacteria 653353657 WP_027501284.1 558 563 yes 2136438 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 640 643 yes 2136439 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 150172 Flavobacterium tegetincola Bacteria 652591654 WP_026976765.1 619 619 yes 2136440 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 948107 Burkholderia sp. WSM3617 Bacteria 652944705 WP_027198185.1 643 644 yes 2136441 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280681 Butyrivibrio sp. WCD2001 Bacteria 651385877 WP_026497959.1 434 434 yes 2136442 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28115 Porphyromonas macacae Bacteria UP000030100 640652964 WP_025079323.1 fig|388739.3.peg.2662 591 591 yes 2136443 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 363870 Bacillus ginsengihumi Bacteria UP000030588 647283724, 724793925 KHD86606.1 WP_025728932.1 594 594 yes 2136444 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 109265 Dolichospermum circinale Bacteria 654624985 WP_028089250.1 455 457 yes 2136445 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55208 Pectobacterium wasabiae Bacteria UP000029436 647648533 WP_025920390.1 631 646 yes 2136446 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 228 Pseudoalteromonas haloplanktis Bacteria 639383431 WP_024608014.1 fig|10090.3.peg.7391 645 650 yes 2136447 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 441 495 yes 2136448 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 415849 Sinobacter flavus Bacteria 654540331 WP_028008184.1 630 633 yes 2136449 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645921432 WP_025475417.1 443 454 yes 2136450 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 64976 Oceanospirillum beijerinckii Bacteria 654847452 WP_028299950.1 624 625 yes 2136451 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646487168 WP_025542579.1 640 646 yes 2136452 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 208085 Saccharomonospora paurometabolica Bacteria 494083288 WP_007025327.1 537 561 yes 2136453 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 134536 Burkholderia caledonica Bacteria 654260258 WP_027775490.1 642 643 yes 2136454 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 384 Rhizobium leguminosarum Bacteria 653810664 WP_027690820.1 436 443 no 2136455 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1520 Clostridium beijerinckii Bacteria UP000031866 648234635 WP_026015784.1 436 436 yes 2136456 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 754500 Bradyrhizobium sp. WSM1417 Bacteria 653398702 WP_027519682.1 623 632 yes 2136457 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1117645 Elizabethkingia anophelis Bacteria UP000053163 639236924 WP_024567610.1 fig|366602.3.peg.1931 602 602 yes 2136458 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454008 Aeromonas hydrophila HZM Bacteria UP000050664 759431756, 651304583 KDV03364.1 WP_043154630.1 645 663 yes 2136459 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 292 Burkholderia cepacia Bacteria UP000063625 654268861 WP_027784016.1 642 643 yes 2136460 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 227866 Bacillus tequilensis Bacteria UP000037765 639658883 WP_024714770.1 fig|355277.4.peg.1810, fig|355276.3.peg.2080, fig|1291206.3.peg.795, fig|1218567.3.peg.3413 589 589 yes 2136461 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 684949 Deinococcus sp. 2009 Bacteria 654853528 WP_028305888.1 603 608 yes 2136462 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1076522 Sediminibacterium sp. OR43 Bacteria 652378602 WP_026774538.1 620 620 yes 2136463 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 653730712 WP_027668144.1 602 608 yes 2136464 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265726 Photobacterium halotolerans Bacteria UP000033633 652999217 WP_027251459.1 635 642 yes 2136465 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 639488668 WP_024660515.1 627 629 yes 2136466 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173 Leptospira interrogans Bacteria UP000037872 642963444 WP_025176507.1 441 495 yes 2136467 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1763 638998602 WP_024451703.1 fig|314283.3.peg.595 515 520 yes 2136468 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 497 647130798 WP_025646182.1 639 661 yes 2136469 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168695 Salinispora tropica Bacteria 648583592 WP_026275343.1 537 537 yes 2136470 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 288965 Clostridium clariflavum Bacteria 653612340 WP_027622819.1 432 432 yes 2136471 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 189425 Paenibacillus graminis Bacteria UP000029500 647255552, 686555661 AIQ66355.1 WP_025704359.1 563 564 yes 2136472 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 556548 Corynebacterium freiburgense Bacteria 652650442 WP_027012994.1 555 558 yes 2136473 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1529 Clostridium cadaveris Bacteria 653634233 WP_027637434.1 434 435 yes 2136474 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375761 Oceanicola nanhaiensis Bacteria 654835784 WP_028288498.1 601 604 yes 2136475 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 648497593 WP_026189344.1 537 537 yes 2136476 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471454 Prochlorococcus sp. scB241_528J8 Bacteria 647657110 WP_025927109.1 451 456 yes 2136477 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 653641362 WP_027644384.1 537 537 yes 2136478 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1286832 Variovorax sp. JGI 0001016-M12 Bacteria 654806296 WP_028259862.1 624 628 yes 2136479 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 538 539 yes 2136480 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 160386 Corynebacterium casei Bacteria 644966421 WP_025387176.1 590 604 yes 2136481 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1173024 Fischerella sp. PCC 9605 Bacteria 652337053 WP_026734268.1 455 459 yes 2136482 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 421 432 yes 2136483 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76594 Cellulophaga baltica Bacteria 639134462 WP_024479958.1 fig|349123.6.peg.107, fig|548485.3.peg.1330, fig|557433.3.peg.1005, fig|585517.3.peg.901, fig|1340495.3.peg.976, fig|557436.4.peg.999, fig|927703.3.peg.42, fig|299033.6.peg.977 619 619 yes 2136484 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 587 608 yes 2136485 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|365044.20.peg.2019 596 603 yes 2136486 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 538 539 yes 2136487 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 454162 Kiloniella laminariae Bacteria 648569927 WP_026261678.1 604 623 yes 2136488 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46206 Pseudobutyrivibrio ruminis Bacteria 654792178 WP_028246143.1 434 435 yes 2136489 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 71657 Brenneria quercina Bacteria 652739537 WP_027064293.1 631 638 yes 2136490 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1283289 Pseudomonas sp. URMO17WK12:I3 Bacteria 654432567 WP_027903282.1 627 628 yes 2136491 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471520 Prochlorococcus sp. scB245a_520E22 Bacteria 647717580 WP_025969983.1 453 456 yes 2136492 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 996925 Mastigocoleus testarum Bacteria 654345668 WP_027839096.1 647 647 yes 2136493 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 221822 Phaeobacter inhibens Bacteria 652995236 WP_027247705.1 594 602 yes 2136494 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76832 Myroides odoratimimus Bacteria UP000052233 640700990 WP_025124590.1 604 604 yes 2136495 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 50338 Rhizobium sullae Bacteria 653378955 WP_027511617.1 601 608 yes 2136496 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 230310 Curvibacter gracilis Bacteria 653280361 WP_027476226.1 616 621 yes 2136497 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 948106 Burkholderia sp. WSM3556 Bacteria 654284819 WP_027799895.1 642 643 yes 2136498 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33045 Bartonella grahamii Bacteria 651388299 WP_026500319.1 602 611 yes 2136499 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1042326 Rhizobium sp. IBUN Bacteria 647179052 WP_025658104.1 601 608 yes 2136500 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1173023 Fischerella sp. PCC 9431 Bacteria 652323150 WP_026720486.1 460 460 yes 2136501 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 63658 Thiomicrospira kuenenii Bacteria 640282929 WP_024850164.1 fig|242507.1.peg.1752 625 633 yes 2136502 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1288080 Streptomyces sp. CNT360 Bacteria 654206665 WP_027739415.1 600 609 yes 2136503 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1381596 Marinimicrobium sp. LS-A18 Bacteria 639057010 WP_024461277.1 fig|207954.4.peg.3174 629 631 yes 2136504 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 340467 Desulfatirhabdium butyrativorans Bacteria 654871516 WP_028323559.1 422 439 no 2136505 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 136992 Methylosarcina lacus Bacteria 635652340 WP_024299211.1 621 622 yes 2136506 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28174 Vibrio ordalii Bacteria 648246355 WP_026027504.1 640 649 yes 2136507 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1172192 Catenovulum agarivorans Bacteria 648235727 WP_026016876.1 640 641 yes 2136508 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 477666 Bacteroides graminisolvens Bacteria 653067036 WP_027318291.1 561 562 yes 2136509 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 996925 Mastigocoleus testarum Bacteria 654347495 WP_027840894.1 456 458 yes 2136510 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 215221, 1432055 Gluconacetobacter rhaeticus, Gluconacetobacter rhaeticus AF1 Bacteria UP000027884 736929614, 651216036 KDU94812.1 WP_034926968.1 605 613 yes 2136511 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645921207 WP_025475192.1 425 436 yes 2136512 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 376470 Olivibacter sitiensis Bacteria 654843565 WP_028296175.1 603 603 yes 2136513 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 88431 Dorea longicatena Bacteria 654621781 WP_028086232.1 435 436 yes 2136514 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1540 Clostridium mangenotii Bacteria 639442021 WP_024621313.1 432 433 yes 2136515 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 374 654686853 WP_028145581.1 623 632 yes 2136516 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 347, 129394 Xanthomonas oryzae, Xanthomonas oryzae pv. oryzicola Bacteria UP000037499, UP000035998 639636849, 856747293, 856741777, 764030425 AKO07487.1, AKO03597.1, AJQ88661.1 WP_024710619.1 fig|375451.6.peg.3282 624 625 yes 2136517 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 611 614 yes 2136518 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1492 Clostridium butyricum Bacteria UP000032253 653631302, 723450344 KHD16447.1 WP_027635485.1 433 433 yes 2136519 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 370776, 1121013 Aspromonas composti, Arenimonas composti DSM 18010 Bacteria UP000029391 652421917, 675597959 KFN49165.1 WP_026817358.1 624 627 yes 2136520 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 94624 Bordetella petrii Bacteria 651853552 WP_026638970.1 636 637 yes 2136521 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 686597 Martelella sp. AD-3 Bacteria 639623372 WP_024707627.1 597 600 yes 2136522 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 620 620 yes 2136523 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646454524 WP_025534034.1 640 646 yes 2136524 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1439319 Citrobacter sp. MGH 55 Bacteria UP000031312 757780396, 635728560 KDF10333.1 WP_042998980.1 625 633 yes 2136525 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1292019 Bacillus sp. 278922_107 Bacteria 654962904 WP_028412684.1 589 589 yes 2136526 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 321846 Pseudomonas simiae Bacteria UP000032100 646232064 AIB34424.1 628 630 yes 2136527 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286 653587886 WP_027600807.1 625 625 yes 2136528 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265 Ruminococcus flavefaciens Bacteria 640308175 WP_024859964.1 437 437 yes 2136529 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 109265 Dolichospermum circinale Bacteria 654617733 WP_028082245.1 455 457 yes 2136530 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 35839 Holophaga foetida Bacteria 491179867 WP_005038230.1 422 437 no 2136531 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47917 Serratia fonticola Bacteria UP000061771 639191847 WP_024531026.1 fig|1131758.3.peg.2179, fig|1131757.3.peg.1559, fig|1198629.3.peg.4459, fig|208964.12.peg.4277, fig|388272.4.peg.4884, fig|6666666.7916.peg.2665, fig|1191475.3.peg.4107 633 647 yes 2136532 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 266854 Granulicoccus phenolivorans Bacteria 652533587 WP_026927591.1 564 570 yes 2136533 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 306 307 no 2136534 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 203 213 no 2136535 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 171674 Inquilinus limosus Bacteria 652475155 WP_026869848.1 600 601 yes 2136536 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1304865 Cellulomonas sp. KRMCY2 Bacteria 635640272 WP_024287165.1 548 550 yes 2136537 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54304 652399055 WP_026794858.1 458 459 yes 2136538 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487, 935590 Neisseria meningitidis, Neisseria meningitidis M0579 Bacteria UP000050419, UP000003557 645198633, 837362577 AKM92608.1 WP_025458586.1 625 633 yes 2136539 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 136849 637098485 WP_024420701.1 fig|675520.3.peg.4227, fig|537209.3.peg.4254, fig|537210.3.peg.276, fig|1246120.3.peg.4183, fig|1200347.3.peg.2333, fig|478433.3.peg.4422, fig|757418.3.peg.4345, fig|652616.3.peg.4375, fig|83331.1.peg.4174, fig|747368.3.peg.4337, fig|1205674.3.peg.761, fig|515617.4.peg.348, fig|757420.3.peg.4342, fig|675522.3.peg.4347, fig|882100.3.peg.4290, fig|443149.4.peg.4441, fig|1240677.3.peg.2259, fig|1205675.3.peg.4320, fig|1306400.3.peg.4451, fig|1246121.3.peg.4183, fig|83332.1.peg.3916, fig|1091501.3.peg.5132, fig|757419.3.peg.4351, fig|336982.3.peg.4145, fig|882099.3.peg.4298, fig|675514.3.peg.4555, fig|757422.3.peg.4339, fig|663886.3.peg.4440, fig|707235.4.peg.4286, fig|757421.3.peg.4350, fig|78331.5.peg.4295, fig|675523.3.peg.4695, fig|1322343.3.peg.15, fig|611302.3.peg.389, fig|520141.3.peg.4226, fig|911237.3.peg.4041, fig|675521.3.peg.4299, fig|675513.3.peg.463, fig|1138877.3.peg.4346, fig|515616.3.peg.4110, fig|1274431.3.peg.3876, fig|882098.3.peg.4283, fig|1126683.4.peg.575, fig|1200348.3.peg.443, fig|675517.3.peg.308, fig|675516.3.peg.467, fig|1126682.4.peg.1787, fig|419947.3.peg.3942, fig|478435.3.peg.1030, fig|443150.4.peg.4349, fig|555461.3.peg.91, fig|747367.3.peg.4337, fig|164513.4.peg.2947, fig|1126684.4.peg.1392, fig|515615.3.peg.4192, fig|757417.4.peg.4344, fig|675518.3.peg.456, fig|659019.3.peg.4070, fig|675515.3.peg.142, fig|747369.3.peg.4330, fig|478434.4.peg.4384, fig|663887.3.peg.4430, fig|1773.31.peg.1743, fig|1279011.3.peg.1334, fig|1078763.3.peg.428, fig|395095.3.peg.4075, fig|675519.3.peg.462, fig|675512.3.peg.4515 628 629 yes 2136540 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 182270 Aurantimonas coralicida Bacteria 636825751 WP_024351833.1 596 602 yes 2136541 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1137269 Streptomyces sp. CNH099 Bacteria 654237166 WP_027752878.1 585 587 yes 2136542 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1443666 Aquimarina megaterium Bacteria 647198939 WP_025664453.1 619 619 yes 2136543 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444055 Escherichia coli, Escherichia coli 3-073-06_S1_C1 Bacteria UP000036210, UP000028099 693112178, 652240519 KDZ46885.1 WP_032263695.1 626 631 yes 2136544 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645918804 WP_025472789.1 441 452 yes 2136545 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471468 Prochlorococcus sp. scB241_529O19 Bacteria 647725804 WP_025975171.1 205 205 no 2136546 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471486 Prochlorococcus sp. scB243_497N18 Bacteria 647693658 WP_025953848.1 453 456 yes 2136547 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 561879 Bacillus safensis Bacteria UP000032451 637155150 WP_024423147.1 fig|1169274.3.peg.1637, fig|1169262.3.peg.1, fig|1213725.3.peg.1555, fig|931437.3.peg.764, fig|1157027.3.peg.591, fig|1075077.3.peg.1524, fig|1157005.3.peg.2245, fig|1214901.3.peg.1069, fig|1224922.3.peg.893, fig|1158487.3.peg.1696, fig|1158535.3.peg.1565, fig|1157019.3.peg.1004, fig|1158515.3.peg.1616, fig|1213732.3.peg.1625, fig|1158466.3.peg.692, fig|931432.3.peg.2456, fig|1158534.3.peg.2759, fig|1158483.3.peg.2222, fig|1213721.3.peg.690, fig|1157022.3.peg.3, fig|1158480.3.peg.883, fig|1158536.3.peg.1073, fig|1169261.3.peg.587, fig|931436.3.peg.1770, fig|1158476.3.peg.1887, fig|1158464.3.peg.2293, fig|1116215.3.peg.2725, fig|1158692.3.peg.1437, fig|1158701.3.peg.1072, fig|1158503.3.peg.3, fig|1157031.3.peg.1862, fig|1224925.3.peg.2470, fig|1213722.3.peg.590, fig|1157030.3.peg.1595, fig|1116218.3.peg.2694, fig|1158697.3.peg.3, fig|1224933.3.peg.881, fig|1224926.3.peg.2255, fig|1116221.3.peg.2689, fig|1158524.3.peg.1601, fig|1158699.3.peg.7, fig|553571.3.peg.2381, fig|1157011.3.peg.586, fig|1116223.3.peg.2786, fig|1158710.3.peg.2267, fig|1224932.3.peg.2235, fig|359787.11.peg.74, fig|1157020.3.peg.2265, fig|904787.3.peg.2463, fig|904335.3.peg.899, fig|158878.1.peg.54, fig|1158512.3.peg.1585, fig|1158694.3.peg.684, fig|553565.3.peg.1295, fig|553592.3.peg.1573, fig|1158489.3.peg.2449, fig|585145.3.peg.1921, fig|1158490.3.peg.1181, fig|1158685.3.peg.825, fig|1158471.3.peg.4, fig|1116224.3.peg.2793, fig|1158695.3.peg.1546, fig|1157034.3.peg.55, fig|1169263.3.peg.2675, fig|1224923.3.peg.1555, fig|1158687.3.peg.1555, fig|1158518.3.peg.2605, fig|1158474.3.peg.748, fig|889933.4.peg.122, fig|1116225.3.peg.2798, fig|1157023.3.peg.698, fig|1158702.3.peg.1525, fig|1157028.3.peg.2385, fig|1169270.3.peg.2757, fig|931452.3.peg.1372, fig|1158492.3.peg.897, fig|1158706.3.peg.1569, fig|904785.3.peg.1569, fig|1224929.3.peg.2465, fig|1213729.3.peg.1522, fig|553601.3.peg.2740, fig|585144.3.peg.2220, fig|931443.3.peg.2198, fig|1158528.3.peg.585, fig|1158479.3.peg.3, fig|1158522.3.peg.2459, fig|1224924.3.peg.583, fig|1169255.3.peg.1574, fig|1157006.3.peg.1179, fig|1157038.3.peg.1547, fig|1158491.3.peg.542, fig|904780.3.peg.1000, fig|1305598.3.peg.1641, fig|553577.3.peg.2793, fig|585154.3.peg.2843, fig|1158538.3.peg.724, fig|553567.3.peg.1416, fig|158879.1.peg.2020, fig|1158501.3.peg.1156, fig|1157015.3.peg.761, fig|931453.3.peg.2332, fig|1138893.3.peg.1987, fig|1158516.3.peg.1128, fig|1157012.3.peg.855, fig|1169272.3.peg.1608, fig|1158484.3.peg.3, fig|1169276.3.peg.1, fig|1303784.3.peg.2439, fig|1158504.3.peg.171, fig|359786.13.peg.1815, fig|553568.3.peg.642, fig|1158462.3.peg.2385, fig|1213727.3.peg.1527, fig|1134814.3.peg.1641, fig|1158510.3.peg.2693, fig|1116222.3.peg.1613, fig|1169258.3.peg.1186, fig|1158511.3.peg.2440, fig|1157008.3.peg.608, fig|931440.3.peg.722, fig|1158704.3.peg.1163, fig|1158686.3.peg.817, fig|1116220.3.peg.48, fig|553596.3.peg.596, fig|1169277.3.peg.4, fig|862516.3.peg.2857, fig|1158505.3.peg.1, fig|1303783.3.peg.1066, fig|1158514.3.peg.2321, fig|904768.3.peg.1425, fig|1158463.3.peg.784, fig|1158703.3.peg.1513, fig|1157014.3.peg.1550, fig|931438.3.peg.1389, fig|1158473.3.peg.2256, fig|1158488.3.peg.1850, fig|1331008.3.peg.2225, fig|1158486.3.peg.1147, fig|1169273.3.peg.3, fig|1158470.3.peg.544, fig|1157004.3.peg.691, fig|1169264.3.peg.1515, fig|1158485.3.peg.466, fig|1116217.3.peg.1556, fig|1158502.3.peg.1638, fig|1213724.3.peg.3, fig|1169266.3.peg.3, fig|1158527.3.peg.746, fig|1303780.3.peg.750, fig|1158472.3.peg.874, fig|1213733.3.peg.1622, fig|703339.3.peg.51, fig|1158499.3.peg.2320, fig|1157033.3.peg.1592, fig|553588.3.peg.2814, fig|546342.4.peg.875, fig|904775.3.peg.2764, fig|1169260.3.peg.1627, fig|1158481.3.peg.2738, fig|1158461.3.peg.1080, fig|1158509.3.peg.585, fig|1157021.3.peg.1210, fig|931435.3.peg.1433, fig|1157036.3.peg.1564, fig|1158513.3.peg.2252, fig|1303787.3.peg.1713, fig|1158498.3.peg.2121, fig|931446.3.peg.2155, fig|1224919.3.peg.739, fig|546340.3.peg.184, fig|1158700.3.peg.692, fig|904723.3.peg.795, fig|553580.3.peg.2857, fig|1158478.3.peg.1852, fig|1213734.3.peg.2685, fig|1134784.3.peg.916, fig|931434.3.peg.582, fig|1157013.3.peg.914, fig|1158468.3.peg.2724, fig|1303781.3.peg.841, fig|1157017.3.peg.3, fig|1323661.3.peg.49, fig|1169257.3.peg.1277, fig|1169275.3.peg.1524, fig|1161392.3.peg.2705, fig|1158497.3.peg.1093, fig|1303786.3.peg.2295, fig|1158696.3.peg.1066, fig|1224920.3.peg.613, fig|1006543.3.peg.2630, fig|1158688.3.peg.1876, fig|1158517.3.peg.594, fig|904792.3.peg.748, fig|931447.3.peg.2289, fig|282458.1.peg.47, fig|1169269.3.peg.1550, fig|1158698.3.peg.815, fig|1169256.3.peg.1612, fig|1158500.3.peg.1425, fig|1157037.3.peg.1569, fig|1233245.3.peg.234, fig|1157025.3.peg.1609, fig|1157039.3.peg.1584, fig|1075082.3.peg.764, fig|1134842.3.peg.2061, fig|176279.3.peg.1218, fig|1075079.3.peg.759, fig|904342.3.peg.1913, fig|1157010.3.peg.2570, fig|1158708.3.peg.2231, fig|1158525.3.peg.1558, fig|1157026.3.peg.9, fig|1158526.3.peg.888, fig|931445.3.peg.2401, fig|543540.3.peg.2588, fig|1224930.3.peg.687, fig|1213726.3.peg.8, fig|1224927.3.peg.2282, fig|931456.3.peg.647, fig|1158469.3.peg.839, fig|1158684.3.peg.1602, fig|1157007.3.peg.1083, fig|1075078.3.peg.762, fig|1303782.3.peg.2328, fig|543538.3.peg.291, fig|1158689.3.peg.1240, fig|1075076.3.peg.1519, fig|1158482.3.peg.1544, fig|904784.3.peg.514, fig|904324.3.peg.1496, fig|1158537.3.peg.1618, fig|1169265.3.peg.693, fig|418127.6.peg.49, fig|1138915.3.peg.2323, fig|1158691.3.peg.3, fig|1158467.3.peg.1362, fig|1158705.3.peg.1155, fig|1157029.3.peg.1543, fig|1157009.3.peg.587, fig|1224921.3.peg.543, fig|1158493.3.peg.2231, fig|585891.3.peg.1708, fig|1116214.3.peg.2708, fig|1158690.3.peg.4, fig|1158494.3.peg.1579, fig|1158711.3.peg.1266, fig|1158682.3.peg.1655, fig|1158533.3.peg.2304, fig|1158523.3.peg.2221, fig|931458.3.peg.2427, fig|1158693.3.peg.587, fig|1158712.3.peg.1531, fig|1158507.3.peg.822, fig|1158709.3.peg.1763, fig|1158475.3.peg.1134, fig|1158521.3.peg.1634, fig|1158531.3.peg.3, fig|1158496.3.peg.2491, fig|1158506.3.peg.1565, fig|1169267.3.peg.2181, fig|1258575.3.peg.1669, fig|1158520.3.peg.882, fig|1235278.3.peg.1643, fig|1213723.3.peg.2651 586 586 yes 2136548 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 225985 Bacillus gelatini Bacteria 651950245 WP_026678809.1 591 592 yes 2136549 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 612 623 yes 2136550 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471437 Prochlorococcus sp. scB241_526B17 Bacteria 647614287 WP_025889589.1 323 325 no 2136551 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1041159 Sinorhizobium terangae WSM1721 Bacteria 651634667 WP_026620837.1 599 610 yes 2136552 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1035120 delta proteobacterium S3R1 Bacteria 644476588 WP_025321470.1 424 426 yes 2136553 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298862 Caulobacter sp. URHA0033 Bacteria 654572399 WP_028039611.1 607 612 yes 2136554 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 604332 Meiothermus sp. CAL-12 Bacteria 654410119 WP_027881681.1 433 435 yes 2136555 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 41297, 322611 Sphingomonas sp. BHC-A Bacteria UP000032306 647355976, 666463796 KEY98681.1 WP_025772785.1 611 619 yes 2136556 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1150398 Arthrobacter sp. 9MFCol3.1 Bacteria 651442978 WP_026538828.1 607 616 yes 2136557 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471495 Prochlorococcus sp. scB243_498L10 Bacteria 647697826 WP_025957025.1 84 85 no 2136558 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471495 Prochlorococcus sp. scB243_498L10 Bacteria 647697828 WP_025957026.1 381 383 no 2136559 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42471 Desulfotomaculum thermocisternum Bacteria 653105955 WP_027355812.1 419 424 yes 2136560 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42471 Desulfotomaculum thermocisternum Bacteria 653105956 WP_027355813.1 421 432 yes 2136561 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471450 Prochlorococcus sp. scB241_527L22 Bacteria 647721617 WP_025972631.1 453 456 yes 2136562 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666563 Aquimarina sp. JAMB N27 Bacteria 639962391 WP_024768258.1 619 619 yes 2136563 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 862720 Acidovorax oryzae Bacteria 651299694 WP_026431394.1 614 617 yes 2136564 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645920476 WP_025474461.1 416 427 yes 2136565 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1033994 Pseudomonas sp. MOIL14HWK12:I2 Bacteria 653587318 WP_027600242.1 625 625 yes 2136566 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 930 Acidithiobacillus thiooxidans Bacteria 640406757 WP_024894270.1 627 628 yes 2136567 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 103730 Actinokineospora inagensis Bacteria 651291124 WP_026423006.1 547 550 yes 2136568 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1257080 Paenibacillus sp. PAMC 26794 Bacteria 648359528 WP_026081306.1 594 594 yes 2136569 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 485 Neisseria gonorrhoeae Bacteria UP000027314 752774347, 831428718, 636866523, 810272954, 810263975, 810256387, 810244101, 810210730, 810208432, 810159082, 810156529, 810122010, 810120538, 810115835, 810111427, 810100495, 810092285, 810087734, 810085471, 810081043, 810072492, 810051338, 802419595, 800586806, 800581899, 800352211, 800243999, 800241868, 800239356, 800155835, 800103827 KLU11878.1, KDN03328.1 WP_041421456.1 625 633 yes 2136570 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 476529 Leisingera aquimarina Bacteria 653006120 WP_027258289.1 596 604 yes 2136571 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 184917 Desulfovibrio magneticus Bacteria 640216215 WP_024825318.1 fig|96561.3.peg.1549 418 439 no 2136572 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 73030 Dechloromonas agitata Bacteria 653251859 WP_027457265.1 637 638 yes 2136573 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 971 Selenomonas ruminantium Bacteria 652363811 WP_026759875.1 437 437 yes 2136574 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 48292 Hyphomicrobium zavarzinii Bacteria 652473472 WP_026868167.1 661 664 yes 2136575 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 208443 Amycolatopsis balhimycina Bacteria 651356288 WP_026468655.1 543 545 yes 2136576 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 612 623 yes 2136577 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 60550 Burkholderia pyrrocinia Bacteria UP000029106 648263690 WP_026044839.1 642 643 yes 2136578 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285268 Acetobacter nitrogenifigens Bacteria 651264405 WP_026397676.1 604 612 yes 2136579 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36812 Mycobacterium genavense Bacteria 647292389 WP_025736974.1 542 545 yes 2136580 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1259801 Pseudomonas sp. LAIL14HWK12:I7 Bacteria 653579031 WP_027592502.1 625 626 yes 2136581 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1163670 Bacteroides sp. 14(A) Bacteria 647280631 WP_025725862.1 573 573 yes 2136582 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571 Klebsiella oxytoca Bacteria UP000030350 640683059, 846724000, 821193847 KMK35323.1, KKY66391.1 WP_025107531.1 fig|157239.3.peg.1328, fig|374933.4.peg.11, fig|262728.1.peg.533 626 631 yes 2136583 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 574962, 1395571 Pseudomonas taeanensis, Pseudomonas taeanensis MS-3 Bacteria UP000030063 640742227, 680316422 KFX71438.1 WP_025164284.1 629 629 yes 2136584 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571 576 yes 2136585 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1071078 Bacillus sp. NSP9.1 Bacteria 651591153 WP_026586126.1 591 591 yes 2136586 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 347 Xanthomonas oryzae Bacteria UP000037499 639807279 WP_024744233.1 fig|350058.5.peg.3743 624 625 yes 2136587 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1076525 Rhodanobacter sp. OR444 Bacteria 653331534 WP_027493829.1 597 600 yes 2136588 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 291995 Pseudomonas azotifigens Bacteria 654787567 WP_028241575.1 627 627 yes 2136589 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 114628 Alkaliphilus transvaalensis Bacteria 651366460 WP_026478766.1 437 437 yes 2136590 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 365528 Frankia sp. BCU110501 Bacteria 648547754 WP_026239505.1 583 614 yes 2136591 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354246 Spongiibacter marinus Bacteria 654397099 WP_027873176.1 625 628 yes 2136592 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550 Enterobacter cloacae Bacteria UP000036177 654547398 WP_028015104.1 626 631 yes 2136593 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29448 Bradyrhizobium elkanii Bacteria UP000032215 654710970 WP_028168896.1 623 632 yes 2136594 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1283291 Pseudomonas sp. URMO17WK12:I11 Bacteria UP000055552 654443456 WP_027913976.1 625 626 yes 2136595 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 108 108 no 2136596 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 640509331 WP_024945664.1 fig|376686.10.peg.1152 645 663 yes 2136597 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44251, 1333534 Paenibacillus durus, Paenibacillus azotofixans ATCC 35681 Bacteria UP000029409, UP000034189 647244128, 818433279 AKG34990.1 WP_025694677.1 578 578 yes 2136598 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1288082 Streptomyces sp. CNH287 Bacteria 654228831 WP_027749041.1 602 603 yes 2136599 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1333846 Paenibacillus sp. 1-18 Bacteria 647275599 WP_025721521.1 595 606 yes 2136600 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 443 444 yes 2136601 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 187328, 1401067 Veillonella montpellierensis, Veillonella montpellierensis DNF00314 Bacteria UP000029628 654804044, 690802791 KGF47997.1 WP_028257677.1 435 436 yes 2136602 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1232410 Desulfuromonas sp. TF Bacteria 654092263 WP_027715897.1 433 433 yes 2136603 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 431041 Candidatus Synechococcus spongiarum Bacteria 647383158 WP_025781318.1 456 457 yes 2136604 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 52698 Actinopolyspora iraqiensis Bacteria 651329592 WP_026453804.1 538 561 yes 2136605 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1906 Streptomyces fradiae Bacteria UP000037185 759753943, 649937764 KDS87696.1 WP_043464485.1 575 591 yes 2136606 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1136432 Streptomyces sp. CNH189 Bacteria 640384171 WP_024886225.1 600 604 yes 2136607 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 628 630 yes 2136608 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1157636 Streptomyces sp. SolWspMP-sol2th Bacteria 654966037 WP_028415784.1 588 601 yes 2136609 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408813 Sphingobacterium sp. H1ai Bacteria 640719110 WP_025142227.1 627 627 yes 2136610 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413479 Solimonas soli Bacteria 654617213 WP_028081757.1 626 629 yes 2136611 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1080179 Burkholderia sp. UYPR1.413 Bacteria 654914993 WP_028365877.1 642 643 yes 2136612 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34072 654177905 WP_027730154.1 624 628 yes 2136613 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 91914, 1382230 Asaia platycodi SF2.1 Bacteria UP000027583 665872642, 642908955 WP_031239849.1 611 622 yes 2136614 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646809785 WP_025589969.1 640 646 yes 2136615 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444204 Escherichia coli, Escherichia coli 2-177-06_S4_C1 Bacteria UP000036210, UP000027700 693096043, 652027934 KDX46617.1 WP_032252833.1 626 631 yes 2136616 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54307 Planktothrix prolifica Bacteria 652401172 WP_026796968.1 458 459 yes 2136617 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 385957 Amycolatopsis sp. ATCC 39116 Bacteria 654465301 WP_027935709.1 542 544 yes 2136618 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1206101 Streptomyces sp. CNR698 Bacteria 654193614 WP_027734093.1 591 595 yes 2136619 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 341225 Clostridium saccharogumia Bacteria 652781552 WP_027088826.1 435 435 yes 2136620 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 647005638 WP_025625030.1 640 646 yes 2136621 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646483024 WP_025541647.1 640 646 yes 2136622 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 82171 Desulfovibrio zosterae Bacteria 654129522 WP_027721973.1 419 421 no 2136623 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408192 Tatumella sp. UCD-D_suzukii Bacteria 647629239 WP_025902271.1 630 641 yes 2136624 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 600 612 yes 2136625 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1163671 Clostridium sp. 12(A) Bacteria 640248671 WP_024837211.1 435 435 yes 2136626 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 933262 Desulfosarcina sp. BuS5 Bacteria 653102704 WP_027352778.1 422 439 yes 2136627 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449046 Bacillus sp. UNC41MFS5 Bacteria 651538439 WP_026564674.1 594 594 yes 2136628 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543 545 yes 2136629 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 218208 Desulfatibacillum aliphaticivorans Bacteria 654862697 WP_028315007.1 429 429 yes 2136630 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 416 416 yes 2136631 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1126 Microcystis aeruginosa Bacteria 640536523 WP_024969783.1 fig|351160.3.peg.2167 457 460 yes 2136632 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1188263 Bradyrhizobium sp. WSM2254 Bacteria 653471070 WP_027547926.1 623 632 yes 2136633 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 558 559 yes 2136634 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1160137 Nocardia sp. BMG111209 Bacteria 648652263 WP_026344010.1 540 541 yes 2136635 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 466153 Singulisphaera acidiphila Bacteria 648230886 WP_026012035.1 445 448 yes 2136636 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 246272 Bacillus bogoriensis Bacteria 651941998 WP_026674996.1 590 590 yes 2136637 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 86664 Bacillus flexus Bacteria 647635741 WP_025908467.1 588 588 yes 2136638 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380376 Pseudomonas sp. URHB0015 Bacteria 653606019 WP_027617502.1 627 629 yes 2136639 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35799 Nitrosospira briensis Bacteria 640613830 WP_025041917.1 623 635 yes 2136640 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 434 465 yes 2136641 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33910 Amycolatopsis mediterranei Bacteria UP000028400 641473679 KDO08349.1 532 534 yes 2136642 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 180498 Jatropha curcas Plants UP000027138 802538480, 643740957 KDP46527.1 XP_012068000.1 548 649 yes 2136643 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543 639209900 WP_024548067.1 626 632 yes 2136644 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1279036 Variovorax sp. JGI 0001013-M04 Bacteria 654181240 WP_027730786.1 381 382 no 2136645 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46206 Pseudobutyrivibrio ruminis Bacteria 654788094 WP_028242092.1 434 435 yes 2136646 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 288 Pseudoalteromonas atlantica Bacteria 639344930 WP_024601665.1 645 650 yes 2136647 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 157784 Pseudomonas thermotolerans Bacteria 654425461 WP_027896663.1 627 627 yes 2136648 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81942, 1348663 Kitasatospora cheerisanensis, Kitasatospora cheerisanensis KCTC 2395 Bacteria UP000027178 737898117, 641394116 KDN84244.1 WP_035864515.1 fig|428127.7.peg.189 592 594 yes 2136649 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1259797 Pseudomonas sp. URMO17WK12:I12 Bacteria 654451572 WP_027922015.1 627 629 yes 2136650 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 492736 Dyadobacter alkalitolerans Bacteria 651644164 WP_026629966.1 626 626 yes 2136651 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1506553 635646658 WP_024293547.1 434 435 yes 2136652 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28130 Prevotella disiens Bacteria 640636500 WP_025064485.1 531 531 yes 2136653 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646357567 WP_025501612.1 640 646 yes 2136654 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1269813 Thioalkalivibrio sp. ALR17-21 Bacteria 636801675 WP_024328611.1 627 629 yes 2136655 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1218 647700521 WP_025958614.1 453 456 yes 2136656 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 186802 646315277 WP_025483879.1 434 435 yes 2136657 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280680 Butyrivibrio sp. LC3010 Bacteria 651398811 WP_026510466.1 434 434 yes 2136658 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|350688.3.peg.821 631 645 yes 2136659 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 363872 Bacillus panaciterrae Bacteria 654950621 WP_028400730.1 591 591 yes 2136660 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 89053 Gordonia amicalis Bacteria 639159840 WP_024500277.1 fig|314266.4.peg.164 551 563 yes 2136661 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53441 Nocardiopsis lucentensis Bacteria 648435516 WP_026127267.1 540 541 yes 2136662 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 526067 Haloglycomyces albus Bacteria 644028471 WP_025272177.1 517 523 yes 2136663 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 113395 Bradyrhizobium sp. Tv2a-2 Bacteria 639178555 WP_024518170.1 fig|357809.4.peg.3365 622 632 yes 2136664 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173365 Methylobacter tundripaludum Bacteria 652889290 WP_027148898.1 625 626 yes 2136665 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 112009 Ignatzschineria larvae Bacteria 652484684 WP_026879290.1 596 596 yes 2136666 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 350893 Flavobacterium daejeonense Bacteria UP000050385 652305971 WP_026712600.1 607 607 yes 2136667 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33074 Zymobacter palmae Bacteria 654058497 WP_027705134.1 613 614 yes 2136668 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|443254.3.peg.1064, fig|390874.10.peg.651 571 572 yes 2136669 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 155920 Xylella fastidiosa subsp. sandyi Ann-1 Bacteria UP000027215 647818193 AIC10308.1 597 618 yes 2136670 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 648582240 WP_026273991.1 537 537 yes 2136671 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82376 Anaeroarcus burkinensis Bacteria 654467566 WP_027937960.1 430 433 yes 2136672 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645917285 WP_025471270.1 412 423 yes 2136673 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 158847 Megamonas hypermegale Bacteria 654418881 WP_027890183.1 433 434 yes 2136674 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1340434 Bacillus sp. UNC438CL73TsuS30 Bacteria 651570414 WP_026572963.1 589 589 yes 2136675 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 13687 646800479 WP_025587256.1 618 631 yes 2136676 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537 537 yes 2136677 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 121428 Sphingobium xenophagum Bacteria 648220914 WP_026002063.1 636 648 yes 2136678 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 939920 Verrucomicrobia bacterium SCGC AAA300-N18 Bacteria 653826350 WP_027693648.1 629 629 yes 2136679 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 614212 Burkholderia sp. OX-01 Bacteria 654762001 WP_028216827.1 642 643 yes 2136680 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 339722 Desulfovermiculus halophilus Bacteria 653120437 WP_027369945.1 415 420 no 2136681 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646568074 WP_025557074.1 640 646 yes 2136682 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 623 Shigella flexneri Bacteria UP000029282 647324457 WP_025760647.1 626 631 yes 2136683 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 348842 Desulfovirgula thermocuniculi Bacteria 654106734 WP_027718630.1 433 433 yes 2136684 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 765414 Burkholderia sp. E25 Bacteria 654301399 WP_027815042.1 642 643 yes 2136685 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408 Bacillus pumilus Bacteria UP000037521 648268971 WP_026050120.1 586 586 yes 2136686 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 407 407 yes 2136687 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 358 Agrobacterium tumefaciens Bacteria UP000064781 646827274 WP_025594493.1 599 607 yes 2136688 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 933262 Desulfosarcina sp. BuS5 Bacteria 653103291 WP_027353355.1 426 426 yes 2136689 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 613202 Prochlorococcus sp. W11 Bacteria 648251637 WP_026032786.1 452 453 yes 2136690 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78527 Rhizobium undicola Bacteria 653313827 WP_027487623.1 598 605 yes 2136691 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1479235 Halomonas sp. HL-48 Bacteria UP000050569 653086014 WP_027336390.1 631 634 yes 2136692 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 121428 Sphingobium xenophagum Bacteria 648457774 WP_026149525.1 640 656 yes 2136693 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470 Acinetobacter baumannii Bacteria UP000028632 638866578 WP_024432841.1 621 625 yes 2136694 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487 Neisseria meningitidis Bacteria UP000050419 645209960 WP_025460695.1 625 633 yes 2136695 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 196490 Bradyrhizobium sp. Ai1a-2 Bacteria 653558004 WP_027584429.1 623 632 yes 2136696 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 647463574 WP_025796255.1 640 646 yes 2136697 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65551, 277 Meiothermus ruber Bacteria UP000032107 654417020, 756399315 KIQ54120.1 WP_027888383.1 434 436 yes 2136698 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646750526 WP_025580447.1 640 645 yes 2136699 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168694 648584118 WP_026275869.1 537 537 yes 2136700 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59617 Helicobacter rodentium Bacteria 652550072 WP_026943721.1 448 448 yes 2136701 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 547, 1594172 Enterobacter sp. BIDMC92 Bacteria UP000035978 647322508, 838706593 KLW90038.1 WP_025759609.1 626 631 yes 2136702 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 213554 Halomonas campaniensis Bacteria UP000027249 740696886, 641742022 AIA75300.1 WP_038482175.1 fig|741161.3.peg.991, fig|392917.4.peg.594 636 648 yes 2136703 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280671 Butyrivibrio sp. FC2001 Bacteria 651921995 WP_026666204.1 434 434 yes 2136704 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444203 Escherichia coli, Escherichia coli 2-156-04_S4_C1 Bacteria UP000036210, UP000027943 692994000, 651735294 KDW14082.1 WP_032181538.1 626 631 yes 2136705 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 81425 Desulfovibrio aminophilus Bacteria 652922372 WP_027176239.1 417 427 no 2136706 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 60035 Geobacter bremensis Bacteria 652447890 WP_026842832.1 437 437 yes 2136707 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 639486928 WP_024659058.1 628 629 yes 2136708 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 408753 Clostridiisalibacter paucivorans Bacteria 652500857 WP_026895246.1 437 437 yes 2136709 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397280 Pseudomonas sp. H1h Bacteria 640685765 WP_025110179.1 fig|375063.4.peg.630 628 629 yes 2136710 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1438694, 1438693 Escherichia coli, Escherichia coli UCI 58, Escherichia coli UCI 57 Bacteria UP000036210, UP000027535, UP000027252 692982241, 635904364, 635901589 KDG84830.1, KDG82081.1 WP_032172136.1 626 631 yes 2136711 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29448 Bradyrhizobium elkanii Bacteria UP000032215 654892580 WP_028344217.1 622 632 yes 2136712 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 641 645 yes 2136713 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1283293 Pseudomonas sp. URIL14HWK12:I6 Bacteria 653598547 WP_027611389.1 628 629 yes 2136714 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 436 437 yes 2136715 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1279036 Variovorax sp. JGI 0001013-M04 Bacteria 654181402 WP_027730828.1 612 615 yes 2136716 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 92181, 1134510 Bartonella koehlerae, Bartonella koehlerae C-29 Bacteria UP000027015 736436801, 654325749 KEC55426.1 WP_034458821.1 602 611 yes 2136717 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28092 Burkholderia andropogonis Bacteria UP000033618 640443328, 805497672 KKB62511.1 WP_024902339.1 647 648 yes 2136718 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 569, 1453496 Hafnia alvei, Hafnia alvei FB1 Bacteria UP000066243, UP000029986 647480290, 700334834 AIU71328.1 WP_025802801.1 631 648 yes 2136719 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645919001 WP_025472986.1 442 456 yes 2136720 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444083 Escherichia coli, Escherichia coli 3-073-06_S1_C2 Bacteria UP000036210, UP000027679 693121685, 652254407 KDZ59699.1 WP_032270607.1 626 631 yes 2136721 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 552 576 yes 2136722 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317577 Deinococcus ficus Bacteria 653265775 WP_027463780.1 603 608 yes 2136723 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265291 Comamonas badia Bacteria 639200489 WP_024538926.1 620 628 yes 2136724 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 640 640 yes 2136725 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 227319 Corynebacterium ciconiae Bacteria 648469759 WP_026161510.1 549 555 yes 2136726 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1336207 Pseudomonas sp. P818 Bacteria 636739298 WP_024306732.1 627 627 yes 2136727 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1693 Bifidobacterium minimum Bacteria UP000029014 651887848 WP_026647455.1 588 862 yes 2136728 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380352 Bradyrhizobium sp. URHA0013 Bacteria 653524466 WP_027570644.1 623 632 yes 2136729 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28128 Prevotella corporis Bacteria 647598244 WP_025874840.1 524 525 yes 2136730 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 494420 Arthrobacter sp. TB 26 Bacteria 636844930 WP_024366375.1 471 479 yes 2136731 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1490 Clostridium bifermentans Bacteria 640740657 WP_025162795.1 437 437 yes 2136732 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168471 Laribacter hongkongensis Bacteria 654311438 WP_027824566.1 633 634 yes 2136733 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410625 Lachnospiraceae bacterium MD2004 Bacteria 653219864 WP_027432423.1 434 435 yes 2136734 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 639513697 WP_024677562.1 fig|6239.3.peg.14652 628 629 yes 2136735 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 989 Marinilabilia salmonicolor Bacteria 640576387 WP_025006774.1 fig|1169232.3.peg.2543, fig|1293913.3.peg.2685, fig|1293912.3.peg.3017, fig|1293920.3.peg.2695, fig|1293917.3.peg.2444, fig|1169230.3.peg.2678, fig|1293916.3.peg.2684, fig|1293919.3.peg.2512, fig|1293915.3.peg.2683, fig|1293914.3.peg.2681, fig|1198678.3.peg.2398, fig|1293921.3.peg.2477, fig|444178.3.peg.397, fig|1293918.3.peg.2699, fig|1293922.3.peg.2535, fig|1169231.3.peg.2692 428 429 yes 2136736 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1499 Clostridium josui Bacteria 640233889 WP_024831307.1 fig|406327.7.peg.1379 436 436 yes 2136737 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265490 Pseudomonas sp. URMO17WK12:I8 Bacteria 654450270 WP_027920719.1 625 626 yes 2136738 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 907 Megasphaera elsdenii Bacteria UP000029696 654423779 WP_027895022.1 433 433 yes 2136739 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 987 Aquimarina latercula Bacteria 653145610 WP_027394818.1 619 619 yes 2136740 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 594 675 yes 2136741 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 173 Leptospira interrogans Bacteria UP000037872 642966812 WP_025179875.1 415 469 no 2136742 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 106592 Ensifer adhaerens Bacteria UP000027454 736803687, 645513298 KDP70519.1 WP_034805694.1 600 607 yes 2136743 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46351 Mycobacterium hassiacum Bacteria 648521468 WP_026213219.1 520 522 yes 2136744 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 653660599 WP_027657167.1 537 537 yes 2136745 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 64972 Oceanobacter kriegii Bacteria 654840267 WP_028292918.1 639 646 yes 2136746 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 153026 Desulforegula conservatrix Bacteria 653111196 WP_027360835.1 434 434 yes 2136747 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2290 Desulfobacter curvatus Bacteria 648567888 WP_026259639.1 433 433 yes 2136748 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 492670 Bacillus methylotrophicus Bacteria UP000032090 647148549 WP_025650302.1 590 590 yes 2136749 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1208600 Bacillus sp. FJAT-14578 Bacteria 654946304 WP_028396467.1 594 594 yes 2136750 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 560 560 yes 2136751 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 468 500 yes 2136752 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 640 649 yes 2136753 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29363 Clostridium paraputrificum Bacteria 652801733 WP_027098647.1 435 435 yes 2136754 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380362 Ralstonia sp. UNC404CL21Col Bacteria 653767626 WP_027678724.1 629 631 yes 2136755 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 548, 1439321, 1439320 Enterobacter aerogenes, Enterobacter aerogenes MGH 62, Enterobacter aerogenes MGH 61 Bacteria UP000056714, UP000027279, UP000027519 695799640, 822812535, 822783415, 822765291, 821190193, 635735667, 635731827 KLF70994.1, KLF42226.1, KLF24291.1, KKY62817.1, KDF17366.1, KDF13563.1 WP_032713824.1 626 631 yes 2136756 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 81424 Clostridium methoxybenzovorans Bacteria 636819478 WP_024345580.1 435 435 yes 2136757 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1283286 Gillisia sp. JM1 Bacteria 652444221 WP_026839216.1 619 619 yes 2136758 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 364763 Ferrimonas kyonanensis Bacteria 654650946 WP_028111959.1 641 652 yes 2136759 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1076592 Acetobacter papayae Bacteria 647582812 WP_025860407.1 606 627 yes 2136760 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1232410 Desulfuromonas sp. TF Bacteria 654096333 WP_027716684.1 434 436 yes 2136761 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 102107 Prunus mume Plants 645216297 XP_008220474.1 543 648 yes 2136762 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1055770 Arthrobacter sp. CAL618 Bacteria 639130921 WP_024477255.1 571 576 yes 2136763 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 629 632 yes 2136764 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298868 Flavobacterium sp. URHB0058 Bacteria 652601940 WP_026983747.1 607 607 yes 2136765 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 64977 Oceanospirillum maris Bacteria 654851194 WP_028303594.1 627 633 yes 2136766 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47917 Serratia fonticola Bacteria UP000061771 639141846, 820752530 AKG69403.1 WP_024485318.1 633 647 yes 2136767 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 561965 Aliagarivorans marinus Bacteria 652582267 WP_026971887.1 640 641 yes 2136768 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 489 Neisseria polysaccharea Bacteria 645193257 WP_025456874.1 625 633 yes 2136769 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 359, 1220581 Agrobacterium rhizogenes, Rhizobium rhizogenes NBRC 13257 Bacteria UP000027865, UP000026941 755120430, 635605976 WP_042470791.1 600 608 yes 2136770 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1173264 Leptolyngbya sp. PCC 6406 Bacteria 495592445 WP_008317024.1 451 454 yes 2136771 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 71657 Brenneria quercina Bacteria 652343718 WP_026740911.1 631 638 yes 2136772 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 639552965 WP_024700238.1 fig|7227.3.peg.5709 640 646 yes 2136773 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 211502 Conchiformibius kuhniae Bacteria 652644654 WP_027009701.1 622 624 yes 2136774 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 286638 Naxibacter alkalitolerans Bacteria 654387280 WP_027865984.1 228 246 no 2136775 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550 Enterobacter cloacae Bacteria UP000036177 654550783 WP_028018468.1 626 631 yes 2136776 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265726 Photobacterium halotolerans Bacteria UP000033633 738862082, 636574559 KDM92091.1 WP_036750879.1 635 642 yes 2136777 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 166314 Synechococcus sp. WH 8109 Bacteria UP000002780 644711006 WP_025362013.1 464 467 yes 2136778 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 63560 Desulfovibrio oxyclinae Bacteria 648475799 WP_026167550.1 426 427 yes 2136779 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 197183 Alkanindiges illinoisensis Bacteria 651359253 WP_026471616.1 625 629 yes 2136780 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|436115.3.peg.4121, fig|1290415.3.peg.2398, fig|320386.3.peg.1876, fig|412022.9.peg.2286, fig|320372.3.peg.2955, fig|272560.6.peg.101, fig|331978.3.peg.5122, fig|536230.4.peg.920, fig|320388.3.peg.1933, fig|1290417.3.peg.3665, fig|334802.3.peg.3368, fig|320387.3.peg.1519, fig|320389.3.peg.1287, fig|1290414.3.peg.4992, fig|320373.3.peg.3851, fig|243160.12.peg.1267, fig|357348.6.peg.115, fig|360118.4.peg.5070, fig|1290412.3.peg.4483, fig|320371.3.peg.2637, fig|1290413.3.peg.1382, fig|412021.3.peg.3766, fig|320390.3.peg.3693, fig|357347.4.peg.554, fig|370895.4.peg.2400, fig|1262664.3.peg.1564, fig|334803.3.peg.609 554 587 yes 2136781 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 60035 Geobacter bremensis Bacteria 652445982 WP_026840970.1 432 435 yes 2136782 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 620 622 yes 2136783 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 400776 Cohnella panacarvi Bacteria 652774007 WP_027084266.1 587 587 yes 2136784 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 514853233 WP_016598140.1 446 457 yes 2136785 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1393 Brevibacillus brevis Bacteria UP000036061 648442508 WP_026134259.1 584 584 yes 2136786 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 357240 Enterobacter helveticus Bacteria 639215735 WP_024553528.1 626 632 yes 2136787 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33938 Geobacillus thermocatenulatus Bacteria 647687361 WP_025949043.1 562 562 yes 2136788 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 647526236 WP_025818845.1 640 646 yes 2136789 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 439 440 yes 2136790 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 426 Methylosinus trichosporium Bacteria 489706530 WP_003610667.1 607 607 yes 2136791 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 648493940 WP_026185691.1 537 537 yes 2136792 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1905 Streptomyces exfoliatus Bacteria 639912216 WP_024760449.1 fig|232721.5.peg.1387, fig|350703.3.peg.4545, fig|1208103.3.peg.3265, fig|1214916.3.peg.3837, fig|1328315.3.peg.2596, fig|795665.3.peg.1003, fig|983919.3.peg.2105, fig|1110502.3.peg.4913, fig|266264.4.peg.2735, fig|1134459.3.peg.2036, fig|1168061.3.peg.5827, fig|1093787.3.peg.2445, fig|1262663.10.peg.3340, fig|798130.4.peg.953, fig|1285581.3.peg.2958 593 595 yes 2136793 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444058, 1444112, 1444086 Escherichia coli, Escherichia coli 3-373-03_S1_C1, Escherichia coli 3-373-03_S1_C3, Escherichia coli 3-373-03_S1_C2 Bacteria UP000036210, UP000027819, UP000028118, UP000028083 693097790, 650123417, 650117134, 650054768 KDU43535.1, KDU37350.1, KDT77264.1 WP_032253998.1 626 631 yes 2136794 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380385 Variovorax sp. URHB0020 Bacteria 654798586 WP_028252516.1 623 628 yes 2136795 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471479 Prochlorococcus sp. scB243_496E10 Bacteria 647664512 WP_025932698.1 381 383 no 2136796 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471479 Prochlorococcus sp. scB243_496E10 Bacteria 647664510 WP_025932697.1 78 79 no 2136797 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1335760 Sphingobium sp. YL23 Bacteria 654589059 WP_028056059.1 619 623 yes 2136798 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287986 Amycolatopsis rifamycinica Bacteria UP000027345 760100496, 637497528 KDN20480.1 WP_043782725.1 fig|996834.3.peg.1830, fig|1291347.3.peg.1962, fig|1291340.3.peg.2798, fig|996836.3.peg.1741, fig|996837.3.peg.2742, fig|267671.1.peg.2569, fig|1291353.3.peg.4711, fig|1291364.3.peg.5055, fig|996827.3.peg.2924, fig|1291341.3.peg.5030, fig|996823.3.peg.1575, fig|1291338.3.peg.4826, fig|996824.3.peg.171, fig|1291339.3.peg.2357, fig|1291366.3.peg.4616, fig|1049908.3.peg.1648, fig|996811.3.peg.3191, fig|996841.3.peg.3563 543 545 yes 2136799 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406 Paenibacillus polymyxa Bacteria UP000031922 647224425 WP_025677466.1 595 604 yes 2136800 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1349818 Herminiimonas sp. CN Bacteria 647644826 WP_025916815.1 636 637 yes 2136801 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1076596 Acetobacter persicus Bacteria 647537681 WP_025825985.1 607 624 yes 2136802 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 925409 Sediminibacterium sp. OR53 Bacteria 652372560 WP_026768516.1 620 620 yes 2136803 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 71657 Brenneria quercina Bacteria 652347037 WP_026744189.1 631 638 yes 2136804 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37637 Corynebacterium pseudodiphtheriticum Bacteria 652659495 WP_027018026.1 603 610 yes 2136805 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646358306 WP_025502187.1 640 646 yes 2136806 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83231 Prevotella brevis Bacteria 653249096 WP_027454534.1 527 528 yes 2136807 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935863 Luteimonas sp. J29 Bacteria 652751849 WP_027071554.1 623 625 yes 2136808 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410616 Pseudobutyrivibrio sp. MD2005 Bacteria 654781003 WP_028235133.1 434 435 yes 2136809 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375 Bradyrhizobium japonicum Bacteria UP000030904 654695300 WP_028153777.1 623 632 yes 2136810 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|314230.4.peg.1941 500 509 yes 2136811 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 133552 Methylocapsa acidiphila Bacteria 651612437 WP_026606567.1 609 610 yes 2136812 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449065 Phyllobacterium sp. UNC302MFCol5.2 Bacteria 652979229 WP_027231833.1 596 600 yes 2136813 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53246 639299843 WP_024589780.1 fig|176299.10.peg.4331 645 650 yes 2136814 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53332 Desulfobulbus elongatus Bacteria 654865184 WP_028317436.1 428 428 yes 2136815 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1381751 Brevibacterium sp. VCM10 Bacteria 647375040 WP_025778575.1 588 602 yes 2136816 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408 Bacillus pumilus Bacteria UP000037521 640667321 WP_025092433.1 fig|403833.5.peg.1170 586 586 yes 2136817 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1196034 Klebsiella sp. 10982 Bacteria 647265399 WP_025713268.1 626 631 yes 2136818 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 448 450 yes 2136819 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 329 Ralstonia pickettii Bacteria UP000029114 640544952 WP_024977103.1 633 635 yes 2136820 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1040985 Mesorhizobium sp. WSM2561 Bacteria 652899996 WP_027155668.1 596 607 yes 2136821 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111804 Actinomadura oligospora Bacteria 651284632 WP_026416589.1 575 580 yes 2136822 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286638 Naxibacter alkalitolerans Bacteria 654387079 WP_027865784.1 635 637 yes 2136823 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408 Bacillus pumilus Bacteria UP000037521 639683585 WP_024718388.1 586 586 yes 2136824 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 349933 Clostridium sp. BL-20 Bacteria 653621982 WP_027632303.1 437 437 yes 2136825 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 816, 1339347, 1339286, 1339346 Bacteroides ovatus str. 3725 D9 iii, Bacteroides fragilis str. 3725 D9 ii, Bacteroides ovatus str. 3725 D1 iv Bacteria UP000028095, UP000028075, UP000028077 696266596, 649537702, 649511222, 649505002 KDS44789.1, KDS19356.1, KDS13262.1 WP_032843587.1 565 565 yes 2136826 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 58116 Glycomyces tenuis Bacteria 652535542 WP_026929496.1 517 520 yes 2136827 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82374 Anaerovibrio lipolyticus Bacteria UP000030993 653147227 WP_027396430.1 436 437 yes 2136828 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|351745.7.peg.773, fig|399804.3.peg.3708, fig|319224.13.peg.2877 626 631 yes 2136829 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29471, 1076138 Pectobacterium atrosepticum, Pectobacterium atrosepticum ICMP 1526 Bacteria UP000028791, UP000036473 746241049, 848271734, 679638436, 679628254, 672931323, 641743781 KMK82273.1, KFX20552.1, KFX10633.1, AIK12158.1, AIA69252.1 WP_039289543.1 631 659 yes 2136830 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 511 Alcaligenes faecalis Bacteria UP000068452 651372174 WP_026484423.1 637 638 yes 2136831 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29448 Bradyrhizobium elkanii Bacteria UP000032215 654898022 WP_028349563.1 632 642 yes 2136832 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471511 Prochlorococcus sp. scB245a_519C7 Bacteria 647702924 WP_025960104.1 453 456 yes 2136833 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1264 Ruminococcus albus Bacteria 640298951 WP_024856378.1 fig|229533.1.peg.7202 437 437 yes 2136834 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 318996 Bradyrhizobium sp. WSM1743 Bacteria 653529473 WP_027572628.1 623 632 yes 2136835 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28051 Lachnospira multipara Bacteria 653218706 WP_027431293.1 438 438 yes 2136836 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 415 Methylobacter luteus Bacteria 652906156 WP_027160163.1 620 621 yes 2136837 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 596 597 yes 2136838 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 433 444 no 2136839 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1235980 Flavobacterium sp. JGI 0001001-D01 Bacteria 646704417 WP_025571242.1 607 607 yes 2136840 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 299567 Adhaeribacter aquaticus Bacteria 651340731 WP_026463717.1 623 623 yes 2136841 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 278991 Aneurinibacillus terranovensis Bacteria 653172831 WP_027415870.1 593 593 yes 2136842 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1071079 Bacillus sp. SB47 Bacteria 651584838 WP_026580017.1 591 591 yes 2136843 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280667 Butyrivibrio sp. VCB2001 Bacteria 651417868 WP_026520842.1 438 441 yes 2136844 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1479237 Marinobacter sp. HL-58 Bacteria UP000050516 654321925 WP_027830948.1 622 625 yes 2136845 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265948 Geobacillus tepidamans Bacteria 653161843 WP_027410771.1 573 573 yes 2136846 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 75684 Balneatrix alpica Bacteria 653060553 WP_027311879.1 622 623 yes 2136847 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 647341823 WP_025768960.1 640 646 yes 2136848 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 228 Pseudoalteromonas haloplanktis Bacteria 639369574 WP_024606377.1 645 650 yes 2136849 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646500996 WP_025544807.1 636 636 yes 2136850 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 654430315 WP_027901177.1 627 629 yes 2136851 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 599 602 yes 2136852 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 91359 Enterovibrio calviensis Bacteria 654556845 WP_028024231.1 637 637 yes 2136853 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543, 1327989 Serratia sp. FS14 Bacteria UP000027246 763150634, 640857520 AIA46618.1 WP_044030299.1 fig|583346.6.peg.322, fig|431943.8.peg.320 632 647 yes 2136854 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 94624 Bordetella petrii Bacteria 654903821 WP_028355204.1 636 637 yes 2136855 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1168169 Methylomonas sp. 11b Bacteria 651608197 WP_026602343.1 621 622 yes 2136856 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 1439326 Enterobacter cloacae, Enterobacter cloacae CHS 79 Bacteria UP000036177, UP000027285 695727988, 635771395 KDF52859.1 WP_032654582.1 626 631 yes 2136857 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471444 Prochlorococcus sp. scB241_527E14 Bacteria 647606500 WP_025882452.1 453 456 yes 2136858 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 264641 Desulfitibacter alkalitolerans Bacteria 654856252 WP_028308594.1 422 433 yes 2136859 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 264641 Desulfitibacter alkalitolerans Bacteria 654856253 WP_028308595.1 422 428 no 2136860 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 148446 Burkholderia sp. A1 Bacteria 640676680 WP_025101414.1 fig|375432.4.peg.1794 642 643 yes 2136861 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 173 173 no 2136862 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408306 Butyrivibrio sp. MC2021 Bacteria 651404615 WP_026516181.1 434 434 yes 2136863 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 80882 Simplicispira psychrophila Bacteria 654526155 WP_027994286.1 611 620 yes 2136864 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 831 Butyrivibrio fibrisolvens Bacteria 652950258 WP_027203664.1 436 437 yes 2136865 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 827 Bacteroides ureolyticus Bacteria 640528017 WP_024961988.1 fig|370438.3.peg.2299 434 435 yes 2136866 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 109327 Anaerovorax odorimutans Bacteria 653149149 WP_027398321.1 437 437 yes 2136867 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 246602 Duganella violaceinigra Bacteria 654641035 WP_028102220.1 618 619 yes 2136868 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 52023 Meiothermus chliarophilus Bacteria 654422464 WP_027893716.1 434 436 yes 2136869 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 31993 640369103 WP_024880553.1 fig|5141.1.peg.1261 610 610 yes 2136870 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 576784 Streptomyces sp. HM35 Bacteria 765006537, 642954869 WP_044572706.1 588 589 yes 2136871 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 228 Pseudoalteromonas haloplanktis Bacteria 639404900 WP_024613057.1 631 636 yes 2136872 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 212667 Vibrio fortis Bacteria UP000027219 695371202, 639231202 KDN27561.1 WP_032552245.1 fig|366394.8.peg.1789, fig|935558.3.peg.6449 640 646 yes 2136873 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 873 Desulfovibrio africanus Bacteria 653118799 WP_027368336.1 418 424 no 2136874 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 542 550 no 2136875 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 311208 Gaetbulibacter saemankumensis Bacteria 652870522 WP_027138046.1 619 619 yes 2136876 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 374106 Campylobacter cuniculorum Bacteria 653054077 WP_027305591.1 429 430 yes 2136877 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 660537 Burkholderia acidipaludis Bacteria 654278311 WP_027793456.1 642 643 yes 2136878 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 159728 Desulfovibrio cuneatus Bacteria 652933602 WP_027187274.1 419 423 no 2136879 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 107401 Tenacibaculum maritimum Bacteria 639781637 WP_024740468.1 fig|326297.10.peg.2311 619 619 yes 2136880 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 85698 Achromobacter xylosoxidans Bacteria UP000056101 651247075 WP_026382151.1 636 637 yes 2136881 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1038867 Bradyrhizobium sp. WSM3983 Bacteria 653426312 WP_027529425.1 623 632 yes 2136882 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 73780 Methylocaldum szegediense Bacteria 651617119 WP_026611235.1 620 624 yes 2136883 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29355 Clostridium cellobioparum Bacteria 653619429 WP_027629805.1 436 436 yes 2136884 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1115632 Arthrobacter sp. 31Y Bacteria 640194443 WP_024817155.1 596 612 yes 2136885 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 1439328 Enterobacter cloacae, Enterobacter cloacae BWH 43 Bacteria UP000036177, UP000027530 695713101, 794272652, 635758633 KJX29626.1, KDF40187.1 WP_032644505.1 626 631 yes 2136886 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 619 627 yes 2136887 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487 Neisseria meningitidis Bacteria UP000050419 645201919 WP_025458871.1 625 633 yes 2136888 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1990 Actinomadura atramentaria Bacteria 648650135 WP_026341886.1 576 578 yes 2136889 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 743974 Moraxella bovoculi 237 Bacteria UP000035860 639140066 KDN25427.1 622 662 yes 2136890 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28141 Cronobacter sakazakii Bacteria UP000027472 696419224, 646211316 KDP97670.1 WP_032989049.1 626 633 yes 2136891 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 183 184 no 2136892 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471489 Prochlorococcus sp. scB243_498B23 Bacteria 647732088 WP_025980061.1 222 222 no 2136893 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61645 Enterobacter asburiae Bacteria UP000036088 640461483 WP_024908254.1 fig|1310164.3.peg.1036, fig|1075088.3.peg.1382, fig|340322.5.peg.1619 626 631 yes 2136894 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384, 1408223 Rhizobium leguminosarum, Rhizobium leguminosarum bv. phaseoli CCGM1 Bacteria UP000027767 739283265, 654361190 KEC70381.1 WP_037146050.1 601 610 yes 2136895 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 374, 29448 Bradyrhizobium elkanii Bacteria UP000032215 639271147, 758536417 KIU44067.1 WP_024579980.1 622 632 yes 2136896 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1283284 Tolumonas sp. BRL6-1 Bacteria 640349699 WP_024873029.1 611 615 yes 2136897 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1557, 1121324 Clostridium litorale, [Clostridium] litorale DSM 5388 Bacteria UP000027946 740429430, 649362341 KDR96245.1 WP_038261940.1 438 438 yes 2136898 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53437 Nocardiopsis alba Bacteria 648433069 WP_026124820.1 544 545 yes 2136899 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 185008 Butyrivibrio hungatei Bacteria 652956149 WP_027209383.1 434 435 yes 2136900 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646468868 WP_025538146.1 640 646 yes 2136901 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 337702 Donghicola xiamenensis Bacteria 654628396 WP_028092591.1 597 602 yes 2136902 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82116 Acetobacterium dehalogenans Bacteria 651260669 WP_026394015.1 421 433 yes 2136903 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 82116 Acetobacterium dehalogenans Bacteria 651260668 WP_026394014.1 421 427 no 2136904 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 464322 Veillonella magna Bacteria 654800673 WP_028254409.1 435 435 yes 2136905 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 460086 Kribbella catacumbae Bacteria 648471145 WP_026162896.1 536 541 yes 2136906 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1131814 Xanthobacter sp. 126 Bacteria 635632668 WP_024279565.1 612 624 yes 2136907 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56448 Xanthomonas arboricola Bacteria UP000050499 640503125 WP_024940095.1 fig|399739.6.peg.1843 624 625 yes 2136908 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 87882, 983594 Burkholderia cepacia ATCC 25416 Bacteria UP000068183 654272789, 685637036 AIO24213.1 WP_027787941.1 642 643 yes 2136909 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 153493 Conchiformibius steedae Bacteria 652666979 WP_027022472.1 622 624 yes 2136910 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 648492937 WP_026184688.1 537 537 yes 2136911 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173 Leptospira interrogans Bacteria UP000037872 642967923 WP_025180986.1 441 495 yes 2136912 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 653778296 WP_027681787.1 603 610 yes 2136913 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645917738 WP_025471723.1 442 456 yes 2136914 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1155954 Paenibacillus sp. 1-49 Bacteria 647229235 WP_025681926.1 593 595 yes 2136915 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 384 Rhizobium leguminosarum Bacteria 653810657 WP_027690818.1 136 140 no 2136916 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28031 Lysinibacillus fusiformis Bacteria UP000029429 640692619 WP_025116939.1 592 592 yes 2136917 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 588605 653043306 WP_027294988.1 437 437 yes 2136918 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 312026 Burkholderia mimosarum Bacteria 654755021 WP_028210120.1 642 643 yes 2136919 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 485 Neisseria gonorrhoeae Bacteria UP000027314 728044083, 636861762 KDM98903.1 WP_033910099.1 625 633 yes 2136920 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1288081 Streptomyces sp. CNQ865 Bacteria 654251483 WP_027766965.1 597 602 yes 2136921 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 648630771 WP_026322522.1 537 537 yes 2136922 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1496721 Butyrivibrio sp. AE3003 Bacteria 651902311 WP_026656879.1 434 435 yes 2136923 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 639471130 WP_024644762.1 627 629 yes 2136924 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1393 Brevibacillus brevis Bacteria UP000036061 648262000 WP_026043149.1 584 584 yes 2136925 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 228 Pseudoalteromonas haloplanktis Bacteria 639354604 WP_024603377.1 641 646 yes 2136926 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2711 Citrus sinensis Plants UP000027120 641847933 KDO66811.1 fig|334803.3.peg.2949, fig|331978.3.peg.3749, fig|884204.3.peg.6825, fig|320371.3.peg.4601, fig|1086034.3.peg.6122, fig|272560.3.peg.2260, fig|1262664.3.peg.6595, fig|320387.3.peg.2794, fig|320389.3.peg.789, fig|412022.9.peg.1237, fig|1290417.3.peg.495, fig|1086036.3.peg.5263, fig|370895.4.peg.786, fig|320372.3.peg.1271, fig|1247713.3.peg.6700, fig|357347.4.peg.4244, fig|412021.3.peg.2377, fig|243160.12.peg.5568, fig|320390.3.peg.4641, fig|1229785.3.peg.6878, fig|331109.3.peg.4782, fig|320386.3.peg.4164, fig|320374.3.peg.4820, fig|1085027.3.peg.5745, fig|320388.3.peg.3630, fig|1086033.3.peg.6161, fig|357348.6.peg.6454, fig|1086032.3.peg.5351, fig|360118.4.peg.963, fig|334802.3.peg.1054 553 667 yes 2136927 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 60547 Burkholderia glathei Bacteria UP000027466 737973589, 646771012, 678298794 KDR41103.1 WP_035936265.1 641 643 yes 2136928 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2711 Citrus sinensis Plants UP000027120 641847939, 641847938, 641847937, 641847936, 641847935, 641847934 KDO66817.1, KDO66816.1, KDO66815.1, KDO66814.1, KDO66813.1, KDO66812.1 fig|320390.4.peg.5270, fig|243160.12.peg.5572, fig|243160.12.peg.5570, fig|243160.12.peg.5571, fig|536230.4.peg.6017, fig|1086034.3.peg.6127, fig|557724.3.peg.5397, fig|1085027.3.peg.5750, fig|412022.9.peg.1240, fig|412022.9.peg.1241, fig|1086036.3.peg.5268, fig|370895.4.peg.789, fig|370895.4.peg.788, fig|370895.4.peg.787, fig|1247713.3.peg.6704, fig|1290414.3.peg.3674, fig|1229785.3.peg.6883, fig|320373.5.peg.6430, fig|412021.3.peg.2374, fig|412021.3.peg.2375, fig|243160.12.peg.5569, fig|412021.3.peg.2372, fig|412021.3.peg.2373, fig|320390.3.peg.4644, fig|334803.3.peg.2953, fig|320390.3.peg.4642, fig|334803.3.peg.2951, fig|334803.3.peg.2950, fig|595498.3.peg.1102, fig|320387.3.peg.2793, fig|320387.3.peg.2792, fig|320387.3.peg.2791, fig|320387.3.peg.2790, fig|320388.3.peg.3632, fig|320388.3.peg.3633, fig|1290413.3.peg.5387, fig|320388.3.peg.3631, fig|357347.4.peg.4239, fig|320388.3.peg.3634, fig|320388.3.peg.3635, fig|425067.3.peg.4526, fig|360118.4.peg.968, fig|1290412.3.peg.5328, fig|1290418.3.peg.3699, fig|331109.4.peg.3585, fig|272560.6.peg.6570, fig|436115.3.peg.2183, fig|320371.4.peg.5690, fig|436115.3.peg.2185, fig|436115.3.peg.2184, fig|412022.9.peg.1239, fig|412022.9.peg.1238, fig|320389.3.peg.785, fig|320389.3.peg.787, fig|320389.3.peg.786, fig|1289589.3.peg.6409, fig|1290415.3.peg.4323, fig|331978.4.peg.6, fig|884204.3.peg.6830, fig|334803.3.peg.2952, fig|436115.3.peg.2182, fig|1262664.3.peg.6600, fig|320389.3.peg.788, fig|320386.3.peg.4166, fig|1290417.3.peg.4774, fig|370895.4.peg.790, fig|1290419.3.peg.2862, fig|1086033.3.peg.6166, fig|334802.3.peg.1058, fig|1086032.3.peg.5356, fig|320386.3.peg.4168, fig|320386.3.peg.4165, fig|357348.6.peg.6459, fig|320386.3.peg.4167, fig|320372.6.peg.5370, fig|334802.3.peg.1055, fig|334802.3.peg.1056, fig|334802.3.peg.1057 553 643 yes 2136929 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204799 Nitratireductor aquibiodomus Bacteria 640601646 WP_025030182.1 fig|611304.3.peg.3853, fig|675517.3.peg.1559, fig|882100.3.peg.1048, fig|572418.5.peg.1051, fig|675513.3.peg.4002, fig|1773.31.peg.2328, fig|611302.3.peg.1427, fig|998089.3.peg.3159, fig|83332.1.peg.958, fig|1806.1.peg.1442, fig|675522.3.peg.798, fig|675521.3.peg.784, fig|1200348.3.peg.3300, fig|663886.3.peg.904, fig|395095.3.peg.121, fig|998090.3.peg.3431, fig|233413.1.peg.969, fig|348776.4.peg.777, fig|998091.3.peg.2724, fig|1126682.4.peg.4174, fig|757422.3.peg.1054, fig|1310115.3.peg.1090, fig|1279011.3.peg.790, fig|747369.3.peg.1054, fig|1200347.3.peg.3340, fig|757419.3.peg.1055, fig|747368.3.peg.1060, fig|478435.3.peg.601, fig|419947.3.peg.971, fig|1078763.3.peg.1460, fig|1240677.3.peg.565, fig|757420.3.peg.1055, fig|675516.3.peg.1350, fig|757417.4.peg.1058, fig|1306400.3.peg.1092, fig|410289.13.peg.1009, fig|336982.3.peg.1009, fig|1091501.3.peg.1254, fig|675514.3.peg.1099, fig|911237.3.peg.747, fig|675520.3.peg.786, fig|443150.4.peg.1056, fig|717522.6.peg.1051, fig|1274431.3.peg.1232, fig|675518.3.peg.1586, fig|1206780.3.peg.1068, fig|659019.3.peg.3009, fig|675523.3.peg.1108, fig|757418.3.peg.1054, fig|757421.3.peg.1056, fig|707237.3.peg.901, fig|747367.3.peg.1056, fig|1305739.3.peg.1151, fig|164513.4.peg.3879, fig|520141.3.peg.598, fig|515616.3.peg.527, fig|478434.4.peg.3369, fig|998092.3.peg.3267, fig|537209.3.peg.1027, fig|675512.3.peg.992, fig|882099.3.peg.1049, fig|561275.4.peg.1072, fig|707235.4.peg.1049, fig|652616.3.peg.1072, fig|663887.3.peg.903, fig|478433.3.peg.1075, fig|520140.3.peg.1240, fig|611303.3.peg.872, fig|555461.3.peg.1493, fig|537210.3.peg.1157, fig|1138877.3.peg.1068, fig|1322343.3.peg.3029, fig|1765.10.peg.4337, fig|882098.3.peg.1040, fig|675519.3.peg.1597, fig|515615.3.peg.739, fig|83331.1.peg.1009, fig|675515.3.peg.1258 597 604 yes 2136930 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 437 437 yes 2136931 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1232447 Clostridiales bacterium VE202-09 Bacteria 639728988 WP_024726480.1 fig|351607.5.peg.223 433 433 yes 2136932 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646545792 WP_025552973.1 640 646 yes 2136933 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1267600 Pantoea sp. IMH Bacteria 640532223 WP_024966027.1 fig|675807.3.peg.3656, fig|1095660.3.peg.3712, fig|345073.12.peg.1728 629 642 yes 2136934 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28885 Hydrogenovibrio marinus Bacteria UP000027341 659863735, 641456274 KDN95940.1 WP_029911058.1 625 633 yes 2136935 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 45462 Brevibacillus borstelensis Bacteria 640553723 WP_024985613.1 fig|349163.14.peg.2308 595 598 yes 2136936 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 939637 gamma proteobacterium SCGC AAA003-E02 Bacteria 646637777 WP_025567949.1 442 442 yes 2136937 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537 537 yes 2136938 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 184607 Crocinitomix catalasitica Bacteria 653183641 WP_027420114.1 627 630 yes 2136939 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 374 653501352 WP_027560692.1 623 632 yes 2136940 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 203699 Derxia gummosa Bacteria 654858323 WP_028310652.1 637 638 yes 2136941 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28174 Vibrio ordalii Bacteria 648247364 WP_026028513.1 640 649 yes 2136942 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 515414 Prevotella falsenii Bacteria 640566827 WP_024997832.1 fig|1157008.3.peg.274, fig|904784.3.peg.2330, fig|904775.3.peg.840, fig|1158708.3.peg.1889, fig|1137129.3.peg.2535, fig|1158486.3.peg.1927, fig|1116219.3.peg.2274, fig|1075078.3.peg.2252, fig|553596.3.peg.1665, fig|1158476.3.peg.1542, fig|546343.3.peg.1335, fig|1229492.3.peg.2279, fig|1157017.3.peg.2404, fig|1158693.3.peg.252, fig|931449.3.peg.275, fig|1158520.3.peg.1651, fig|1214901.3.peg.733, fig|1157025.3.peg.2347, fig|1157010.3.peg.2230, fig|931455.3.peg.282, fig|1161392.3.peg.1801, fig|1303784.3.peg.554, fig|1158517.3.peg.250, fig|1118959.3.peg.2277, fig|451515.3.peg.2520, fig|1158523.3.peg.273, fig|904771.3.peg.2325, fig|904795.7.peg.1988, fig|1158504.3.peg.2486, fig|1158498.3.peg.250, fig|1158689.3.peg.1971, fig|904785.3.peg.1410, fig|931439.3.peg.268, fig|1158466.3.peg.350, fig|948563.3.peg.1334, fig|1169274.3.peg.2372, fig|553590.4.peg.1023, fig|904726.3.peg.1768, fig|1158702.3.peg.2322, fig|904745.3.peg.906, fig|1169277.3.peg.2408, fig|1157000.3.peg.2392, fig|93061.3.peg.2557, fig|904787.3.peg.410, fig|1231382.3.peg.418, fig|426430.6.peg.2243, fig|1303787.3.peg.2457, fig|1158522.3.peg.481, fig|1157033.3.peg.2263, fig|1158467.3.peg.2013, fig|931454.3.peg.245, fig|1158475.3.peg.800, fig|1157005.3.peg.1906, fig|1157020.3.peg.1931, fig|553573.3.peg.809, fig|282459.1.peg.2285, fig|1158705.3.peg.1929, fig|1157026.3.peg.2342, fig|1224922.3.peg.550, fig|451516.9.peg.2509, fig|904766.3.peg.1714, fig|1213733.3.peg.2357, fig|1156995.3.peg.357, fig|904754.3.peg.2006, fig|904753.3.peg.448, fig|1158484.3.peg.2298, fig|1147034.3.peg.2493, fig|1137130.3.peg.1304, fig|1158465.3.peg.259, fig|1157023.3.peg.361, fig|1158462.3.peg.422, fig|1116221.3.peg.2174, fig|1157031.3.peg.1528, fig|452948.4.peg.536, fig|904723.3.peg.2305, fig|359787.11.peg.2544, fig|931433.3.peg.278, fig|1075076.3.peg.2255, fig|1158524.3.peg.2365, fig|1224920.3.peg.280, fig|904739.3.peg.1367, fig|681288.4.peg.2444, fig|1158470.3.peg.206, fig|1116215.3.peg.2236, fig|553567.3.peg.764, fig|1158538.3.peg.385, fig|1158471.3.peg.2331, fig|1137132.3.peg.2168, fig|1278072.4.peg.2059, fig|1221452.3.peg.999, fig|1158472.3.peg.533, fig|1158495.3.peg.2361, fig|904786.3.peg.1867, fig|644279.4.peg.2560, fig|1158489.3.peg.548, fig|1169263.3.peg.2331, fig|1155079.3.peg.816, fig|1158478.3.peg.1510, fig|418127.4.peg.2217, fig|1258575.3.peg.1031, fig|1158533.3.peg.1967, fig|931448.3.peg.254, fig|1323661.3.peg.2409, fig|1169272.3.peg.2343, fig|1158487.3.peg.2426, fig|889933.4.peg.2200, fig|1116225.3.peg.2308, fig|1075077.3.peg.2259, fig|904781.3.peg.2192, fig|1157037.3.peg.2345, fig|1158485.3.peg.804, fig|1242970.3.peg.2363, fig|1213727.3.peg.2339, fig|931451.3.peg.279, fig|904778.3.peg.245, fig|553568.3.peg.2749, fig|1303785.3.peg.347, fig|1303782.3.peg.391, fig|1169261.3.peg.252, fig|1158698.3.peg.480, fig|1157012.3.peg.520, fig|553581.3.peg.2475, fig|1157019.3.peg.662, fig|1158516.3.peg.1897, fig|1158699.3.peg.2432, fig|931443.3.peg.249, fig|754025.3.peg.2452, fig|1158686.3.peg.477, fig|1158493.3.peg.1891, fig|904747.3.peg.1847, fig|1158515.3.peg.2358, fig|1157036.3.peg.2340, fig|548474.3.peg.461, fig|553577.3.peg.246, fig|904783.3.peg.2580, fig|762962.3.peg.2091, fig|1221451.3.peg.2071, fig|1157009.3.peg.251, fig|1213726.3.peg.2375, fig|931434.3.peg.247, fig|904743.3.peg.871, fig|1278074.4.peg.1127, fig|1158510.3.peg.2349, fig|1278071.4.peg.907, fig|1157006.3.peg.1918, fig|1169266.3.peg.2269, fig|1158491.3.peg.205, fig|1123523.3.peg.2360, fig|948561.3.peg.1469, fig|1158703.3.peg.2310, fig|1158539.3.peg.2427, fig|904749.3.peg.801, fig|931444.3.peg.285, fig|1157024.3.peg.380, fig|1134842.3.peg.1340, fig|904732.3.peg.102, fig|1283278.3.peg.2169, fig|1158535.3.peg.2323, fig|1158507.3.peg.483, fig|1169262.3.peg.2339, fig|1158474.3.peg.1537, fig|931440.3.peg.382, fig|1303783.3.peg.1858, fig|1158706.3.peg.2328, fig|585891.3.peg.2495, fig|1158513.3.peg.1918, fig|1158692.3.peg.2169, fig|1158521.3.peg.2369, fig|931432.3.peg.251, fig|1224927.3.peg.1947, fig|1158488.3.peg.1506, fig|1157003.3.peg.256, fig|1158683.3.peg.1879, fig|1158464.3.peg.1950, fig|1158518.3.peg.651, fig|1156998.3.peg.1805, fig|931441.3.peg.1608, fig|1169267.3.peg.1839, fig|1156999.3.peg.2345, fig|1112349.3.peg.2537, fig|1158694.3.peg.351, fig|754026.3.peg.1891, fig|1213724.3.peg.2353, fig|904768.3.peg.1120, fig|1158473.3.peg.1916, fig|904744.3.peg.1796, fig|1278075.4.peg.218, fig|703339.3.peg.2405, fig|1116216.3.peg.2198, fig|1224921.3.peg.1323, fig|904759.3.peg.1596, fig|1169268.3.peg.253, fig|1158506.3.peg.2324, fig|1158512.3.peg.2354, fig|1158509.3.peg.251, fig|1169257.3.peg.2011, fig|1156994.3.peg.1895, fig|904313.3.peg.481, fig|1158690.3.peg.2345, fig|1158704.3.peg.1897, fig|1169258.3.peg.1920, fig|1157035.3.peg.1837, fig|505321.3.peg.203, fig|1213732.3.peg.2365, fig|1224928.3.peg.2006, fig|1158468.3.peg.2384, fig|359786.13.peg.2581, fig|1158511.3.peg.483, fig|931442.3.peg.253, fig|553601.3.peg.1913, fig|1303781.3.peg.497, fig|196620.1.peg.2339, fig|1157032.3.peg.1971, fig|904767.3.peg.1040, fig|904750.3.peg.2128, fig|1235277.3.peg.2349, fig|862516.3.peg.420, fig|553594.3.peg.374, fig|1157002.3.peg.2109, fig|1158707.3.peg.256, fig|1213728.3.peg.1991, fig|1169275.3.peg.2317, fig|1231383.3.peg.7, fig|904780.3.peg.220, fig|904777.3.peg.950, fig|1226740.3.peg.349, fig|1158696.3.peg.728, fig|1158682.3.peg.2421, fig|1158492.3.peg.554, fig|1158701.3.peg.736, fig|1158501.3.peg.1888, fig|450394.6.peg.2201, fig|904730.3.peg.1692, fig|1158525.3.peg.2296, fig|1158482.3.peg.2284, fig|1116223.3.peg.2367, fig|1169256.3.peg.2353, fig|904731.3.peg.464, fig|1157014.3.peg.2280, fig|904738.3.peg.1558, fig|1137133.3.peg.2150, fig|931450.3.peg.252, fig|1158479.3.peg.2326, fig|158878.1.peg.2416, fig|1158712.3.peg.2325, fig|1213722.3.peg.252, fig|1157018.3.peg.1777, fig|543540.3.peg.2371, fig|904779.3.peg.1134, fig|1224930.3.peg.350, fig|1156997.3.peg.2417, fig|1158691.3.peg.2309, fig|1158700.3.peg.357, fig|1158494.3.peg.2352, fig|1157011.3.peg.252, fig|1303780.3.peg.1547, fig|1075082.3.peg.2255, fig|1158684.3.peg.2336, fig|273036.3.peg.2233, fig|1158500.3.peg.2161, fig|1156996.3.peg.1897, fig|1213734.3.peg.2345, fig|1158496.3.peg.2149, fig|1303786.3.peg.390, fig|1224924.3.peg.250, fig|931457.3.peg.258, fig|1235276.3.peg.2645, fig|904760.3.peg.2199, fig|1224923.3.peg.2292, fig|1216363.3.peg.2406, fig|1169264.3.peg.2269, fig|1235278.3.peg.2595, fig|1169269.3.peg.2320, fig|1158514.3.peg.1980, fig|1158528.3.peg.251, fig|1158685.3.peg.491, fig|553565.3.peg.1985, fig|367830.3.peg.513, fig|1224929.3.peg.2133, fig|553580.3.peg.247, fig|1074252.3.peg.2345, fig|1224919.3.peg.404, fig|1241616.3.peg.1784, fig|1158463.3.peg.451, fig|1157039.3.peg.2369, fig|553571.3.peg.1508, fig|1213721.3.peg.350, fig|1157015.3.peg.423, fig|1213725.3.peg.2332, fig|1158481.3.peg.2403, fig|553583.3.peg.2592, fig|1158505.3.peg.663, fig|1157004.3.peg.354, fig|1116220.3.peg.2324, fig|1235275.3.peg.2599, fig|1158508.3.peg.2321, fig|1075079.3.peg.2248, fig|931460.3.peg.2367, fig|931446.3.peg.248, fig|561307.5.peg.1921, fig|904729.3.peg.778, fig|1288493.3.peg.329, fig|553592.3.peg.562, fig|1158483.3.peg.1880, fig|908247.3.peg.2078, fig|1157038.3.peg.2310, fig|1028799.3.peg.2178, fig|1157029.3.peg.2278, fig|904727.3.peg.2515, fig|680649.3.peg.2301, fig|1116217.3.peg.2294, fig|1169276.3.peg.2319, fig|1158502.3.peg.2383, fig|1158499.3.peg.1985, fig|1158497.3.peg.1885, fig|1157021.3.peg.1943, fig|1331008.3.peg.436, fig|1158480.3.peg.539, fig|1169270.3.peg.2422, fig|1158536.3.peg.736, fig|1157007.3.peg.749, fig|1158531.3.peg.2279, fig|1224931.3.peg.1820, fig|1213729.3.peg.2299, fig|1158503.3.peg.2333, fig|1157001.3.peg.255, fig|931458.3.peg.249, fig|93062.19.peg.2358, fig|1158687.3.peg.2331, fig|1158526.3.peg.551, fig|685039.3.peg.2531, fig|1157022.3.peg.2373, fig|1158490.3.peg.1930, fig|1158697.3.peg.2326, fig|904724.3.peg.2781, fig|546342.3.peg.1523, fig|1221453.3.peg.54, fig|904737.3.peg.2521, fig|1116222.3.peg.2348, fig|1305598.3.peg.2396, fig|869816.3.peg.2436, fig|1116224.3.peg.2336, fig|1116218.3.peg.2262, fig|985006.4.peg.2219, fig|1157030.3.peg.2329, fig|904763.3.peg.2221, fig|543539.3.peg.1306, fig|1213730.3.peg.790, fig|1155084.3.peg.2197, fig|1158688.3.peg.1534, fig|1157013.3.peg.579, fig|1144272.3.peg.1263, fig|1158530.3.peg.253, fig|1224933.3.peg.544, fig|1158529.3.peg.2454, fig|1169260.3.peg.2295, fig|455227.3.peg.793, fig|1158710.3.peg.1923, fig|1157027.3.peg.253, fig|1224925.3.peg.531, fig|1224926.3.peg.1920, fig|1006543.3.peg.2402, fig|158879.1.peg.2289, fig|1158695.3.peg.2326, fig|1158537.3.peg.2351, fig|553588.3.peg.2565, fig|1213723.3.peg.2312, fig|904792.3.peg.1726, fig|1169273.3.peg.2302, fig|904782.3.peg.530, fig|904776.3.peg.133, fig|548475.3.peg.1750, fig|1158709.3.peg.2430, fig|1116214.3.peg.2279, fig|931459.3.peg.240, fig|1158461.3.peg.1879, fig|553574.3.peg.1206, fig|1157016.3.peg.511, fig|1158527.3.peg.1550, fig|1224932.3.peg.1894, fig|1157034.3.peg.2487, fig|1158469.3.peg.500, fig|1144271.3.peg.1705, fig|1169265.3.peg.355, fig|1158711.3.peg.2005, fig|1265302.3.peg.2645, fig|904725.3.peg.1837 526 526 yes 2136943 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28115 Porphyromonas macacae Bacteria UP000030100 640572708 WP_025003429.1 fig|413999.4.peg.1043, fig|441771.4.peg.1026, fig|441770.4.peg.1028 591 591 yes 2136944 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 136849, 237306 Pseudomonas syringae pv. persicae Bacteria UP000034346 639497833, 814994993 KKI24653.1 WP_024668475.1 fig|7955.3.peg.14126 628 629 yes 2136945 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1340430 Bacillus sp. UNC437CL72CviS29 Bacteria 651599090 WP_026594013.1 586 586 yes 2136946 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33069 Pseudomonas viridiflava Bacteria UP000049942 648211303 WP_025993241.1 627 629 yes 2136947 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314722 Pseudoxanthomonas suwonensis Bacteria UP000033067 640335660 WP_024867654.1 622 625 yes 2136948 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 348842 Desulfovirgula thermocuniculi Bacteria 654099393 WP_027717118.1 418 423 yes 2136949 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935836 Bacillus sp. J33 Bacteria 651585580 WP_026580753.1 594 594 yes 2136950 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 640 658 yes 2136951 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 628 691 yes 2136952 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 587753 Pseudomonas chlororaphis Bacteria UP000027603 647495109 WP_025808101.1 628 629 yes 2136953 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 290732 Aminiphilus circumscriptus Bacteria 649574665 WP_026368348.1 420 433 yes 2136954 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1120797 Mycobacterium sp. 141 Bacteria 648664886 WP_026356633.1 539 542 yes 2136955 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 576 576 yes 2136956 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645920031 WP_025474016.1 422 433 yes 2136957 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294 Pseudomonas fluorescens Bacteria UP000060991 639429141 WP_024618002.1 628 629 yes 2136958 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901 Salmonella enterica Bacteria UP000054489 640129734 WP_024798269.1 fig|331978.4.peg.665, fig|1086033.3.peg.3311, fig|1086032.3.peg.2881, fig|320373.5.peg.3534, fig|1290419.3.peg.4602 626 631 yes 2136959 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280684 Butyrivibrio sp. FCS006 Bacteria 651410980 WP_026518834.1 439 441 yes 2136960 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 141693 Nocardiopsis kunsanensis Bacteria 648423847 WP_026115598.1 537 539 yes 2136961 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1218 647685431 WP_025947589.1 453 456 yes 2136962 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1232683 Marinobacterium sp. AK27 Bacteria UP000028252 738235499, 653655549 KEA62549.1 WP_036190822.1 624 624 yes 2136963 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287 Pseudomonas aeruginosa Bacteria UP000065817 653262007 KEA41719.1 512 512 yes 2136964 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 640 644 yes 2136965 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 619 yes 2136966 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471469 Prochlorococcus sp. scB243_495D8 Bacteria 647653110 WP_025923656.1 453 456 yes 2136967 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36832 Clostridium aerotolerans Bacteria 652498411 WP_026892860.1 435 435 yes 2136968 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 610 624 yes 2136969 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1176 Aphanizomenon flos-aquae Bacteria 653153843 WP_027402860.1 455 457 yes 2136970 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280682 Butyrivibrio sp. XBB1001 Bacteria 651376153 WP_026488376.1 434 434 yes 2136971 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1421 Lysinibacillus sphaericus Bacteria UP000028424 636838983 WP_024360748.1 592 592 yes 2136972 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 392320 Burkholderia nodosa Bacteria 654749019 WP_028204227.1 642 643 yes 2136973 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 538 539 yes 2136974 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82981, 1005999 Leminorella grimontii, Leminorella grimontii ATCC 33999 Bacteria UP000028624 653023913, 668979564 KFC93242.1 WP_027275793.1 625 636 yes 2136975 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1525 Moorella thermoacetica Bacteria UP000067720 647361607 WP_025774924.1 431 432 yes 2136976 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 99286 Flavobacterium frigidarium Bacteria 652299384 WP_026709595.1 607 607 yes 2136977 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|1765.116.peg.10963, fig|319017.3.peg.6686, fig|319003.3.peg.3951, fig|1040988.3.peg.618, fig|1144344.3.peg.2511, fig|551947.3.peg.2340, fig|288000.5.peg.1789, fig|551936.3.peg.5834, fig|224911.1.peg.7548, fig|566679.3.peg.3630, fig|1038862.3.peg.4155, fig|1037409.3.peg.1757, fig|114615.3.peg.5900, fig|115808.3.peg.2488, fig|335659.3.peg.6223, fig|1245469.3.peg.6458, fig|1038866.3.peg.907 564 564 yes 2136978 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375 Bradyrhizobium japonicum Bacteria UP000030904 654698172, 712706385 KGT81453.1 WP_028156320.1 623 632 yes 2136979 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 647464623 WP_025796539.1 640 646 yes 2136980 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1286363 Bacillus sp. 171095_106 Bacteria 654960517 WP_028410321.1 589 589 yes 2136981 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1117645, 1338011 Elizabethkingia anophelis, Elizabethkingia anophelis NUHP1 Bacteria UP000053163, UP000028933 639234823, 675105326 AIL46619.1 WP_024565816.1 fig|366602.3.peg.3929 602 602 yes 2136982 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 135621, 400095, 706570 Pseudomonas tuomuerensis, Serpens flexibilis Bacteria UP000030980, UP000031027 653575347, 735690981, 733455932 KHO64589.1, KHL71209.1 WP_027589041.1 626 626 yes 2136983 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645920905 WP_025474890.1 421 432 yes 2136984 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543, 573, 1438754, 1438749 Klebsiella pneumoniae, Klebsiella pneumoniae CHS 48, Klebsiella pneumoniae CHS 43 Bacteria UP000036212, UP000027013, UP000027568 694105251, 839578139, 636187462, 636168718 KMG53519.1, KDJ65838.1, KDJ47208.1 WP_032448192.1 626 631 yes 2136985 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 164546 Cupriavidus taiwanensis Bacteria 646793144 WP_025586384.1 624 626 yes 2136986 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 400948 Deefgea rivuli Bacteria 653271086 WP_027469027.1 641 641 yes 2136987 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 90728 Desulfobacterium anilini Bacteria 654868603 WP_028320754.1 427 427 yes 2136988 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408 Bacillus pumilus Bacteria UP000037521 637175539 WP_024427852.1 fig|170187.1.peg.2001 586 586 yes 2136989 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1444288 Enterobacter sp. 5-4 Bacteria 647637765 WP_025910406.1 626 631 yes 2136990 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1229486 gamma proteobacterium L18 Bacteria 654510439 WP_027979745.1 628 629 yes 2136991 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615 874 yes 2136992 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 508770 Sciscionella marina Bacteria 648506351 WP_026198102.1 528 545 yes 2136993 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 638 Arsenophonus nasoniae Bacteria 652428215 WP_026823513.1 624 644 yes 2136994 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1395570 Burkholderia cepacia JBK9 Bacteria UP000032941 651416828 KDV26257.1 530 531 yes 2136995 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 434 434 yes 2136996 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83231 Prevotella brevis Bacteria 653243528 WP_027449088.1 527 528 yes 2136997 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 542 544 yes 2136998 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537 537 yes 2136999 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1122941 Pedobacter glucosidilyticus Bacteria UP000031461 652509069 WP_026903366.1 627 627 yes 2137000 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 198, 91352 Campylobacter hyointestinalis, Campylobacter hyointestinalis subsp. hyointestinalis Bacteria UP000027871 736967226, 653288727 KEA43823.1 WP_034963688.1 449 450 yes 2137001 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28174 Vibrio ordalii Bacteria 648247101 WP_026028250.1 640 649 yes 2137002 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645917689 WP_025471674.1 423 434 yes 2137003 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173 Leptospira interrogans Bacteria UP000037872 642967055 WP_025180118.1 495 495 yes 2137004 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 647011109 WP_025626163.1 640 646 yes 2137005 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173 Leptospira interrogans Bacteria UP000037872 642963758 WP_025176821.1 492 492 yes 2137006 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 194963, 1408224 Sinorhizobium americanum, Sinorhizobium americanum CCGM7 Bacteria UP000027923 739522701, 654371080 KEC80025.1 WP_037381984.1 599 611 yes 2137007 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1160 Planktothrix agardhii Bacteria 652997272 WP_027249738.1 458 459 yes 2137008 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59512 Planktothrix rubescens Bacteria 652392743 WP_026788590.1 458 459 yes 2137009 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645921254 WP_025475239.1 442 456 yes 2137010 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392488 Leeuwenhoekiella sp. Hel_I_48 Bacteria 654926779 WP_028377276.1 618 618 yes 2137011 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 871325 Bacteroides sp. JCM 17102 Bacteria 640646782 WP_025073564.1 fig|391593.3.peg.242 562 562 yes 2137012 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1353531 Ensifer sp. TW10 Bacteria 651620600 WP_026614694.1 599 610 yes 2137013 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 589 589 yes 2137014 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1040989 Bradyrhizobium sp. ARR65 Bacteria 639171342 WP_024511088.1 fig|384035.3.peg.605, fig|163164.1.peg.822 622 632 yes 2137015 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43305 Clostridium proteoclasticum Bacteria 651892859 WP_026652075.1 433 434 yes 2137016 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 295 313 no 2137017 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1076 Rhodopseudomonas palustris Bacteria UP000032515 653025931 WP_027277750.1 631 641 yes 2137018 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1382359 Acidobacterium sp. PMMR2 Bacteria 651318688 WP_026443186.1 487 490 yes 2137019 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1355376 Arcobacter sp. AF1581 Bacteria 652407205 WP_026802945.1 448 450 yes 2137020 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 578 578 yes 2137021 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444099 Escherichia coli, Escherichia coli 2-427-07_S1_C3 Bacteria UP000036210, UP000028035 693027238, 652177165 KDY86937.1 WP_032203511.1 626 631 yes 2137022 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 335972 Vibrio litoralis Bacteria 653843839 WP_027695418.1 640 654 yes 2137023 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68287 640484671 WP_024924631.1 fig|349102.13.peg.3212 604 610 yes 2137024 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 997829 Porphyromonas sp. KLE 1280 Bacteria UP000027933 763245119, 650332258 KDU79388.1 WP_044114214.1 596 603 yes 2137025 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43357 Kutzneria albida Bacteria 644673190 WP_025354158.1 544 546 yes 2137026 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646882012 WP_025607644.1 640 646 yes 2137027 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 588932 Brevundimonas sp. BIO-TAS2-2 Bacteria 647728066 WP_025976869.1 618 644 yes 2137028 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|391296.7.peg.895 634 659 yes 2137029 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570 636834703 WP_024360692.1 626 631 yes 2137030 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82367 Paracoccus pantotrophus Bacteria 640267029 WP_024844188.1 598 601 yes 2137031 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 256035 Glycomyces arizonensis Bacteria 652528351 WP_026922432.1 539 542 yes 2137032 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 329 Ralstonia pickettii Bacteria UP000029114 640541733 WP_024973895.1 fig|443906.13.peg.2506 633 635 yes 2137033 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 601 610 yes 2137034 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1814 Amycolatopsis methanolica Bacteria 648461814 WP_026153565.1 542 544 yes 2137035 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 134537 Burkholderia fungorum Bacteria UP000032614 654744189, 780553789 AJZ57815.1 WP_028200371.1 642 643 yes 2137036 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444053 Escherichia coli, Escherichia coli 1-392-07_S1_C1 Bacteria UP000036210, UP000027671 693149147, 651793631 KDW69770.1 WP_032287108.1 626 631 yes 2137037 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471472 Prochlorococcus sp. scB243_495K23 Bacteria 647726384 WP_025975606.1 453 456 yes 2137038 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 624 624 yes 2137039 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42471 Desulfotomaculum thermocisternum Bacteria 653107459 WP_027357297.1 433 433 yes 2137040 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 639538961 WP_024687550.1 fig|7227.3.peg.11348 627 629 yes 2137041 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 589537 Prevotella dentasini Bacteria 640572321 WP_025003069.1 fig|413999.4.peg.665, fig|441771.4.peg.648, fig|441770.4.peg.655 527 528 yes 2137042 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 568 568 yes 2137043 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 77635 Bifidobacterium subtile Bacteria UP000029055 673003981 KFI99017.1 595 882 yes 2137044 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1340435 Chryseobacterium sp. UNC8MFCol Bacteria 653123588 WP_027373024.1 603 603 yes 2137045 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 639477240 WP_024650480.1 627 629 yes 2137046 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1379686 Streptomyces sp. AW19M42 Bacteria 639147424 WP_024489560.1 fig|208964.1.peg.5125, fig|665948.3.peg.2345, fig|1211113.3.peg.2946, fig|388272.4.peg.5548, fig|1134459.3.peg.4893, fig|1051003.3.peg.5841, fig|1163392.3.peg.5676, fig|983918.3.peg.4446, fig|983919.3.peg.4723, fig|798130.4.peg.4077, fig|1285581.3.peg.2057, fig|1089456.3.peg.383, fig|1328315.3.peg.5864, fig|1191475.3.peg.5198, fig|1280938.3.peg.5491, fig|509633.3.peg.5285, fig|1169413.3.peg.3725, fig|1193501.3.peg.2012, fig|1009714.6.peg.5678, fig|1051004.3.peg.5806, fig|1131757.3.peg.4607, fig|1286151.3.peg.3962, fig|1163393.3.peg.6055, fig|1163394.3.peg.5737, fig|208963.12.peg.5559, fig|1331059.3.peg.5046, fig|1163397.3.peg.5586, fig|1214916.3.peg.1909, fig|381754.5.peg.5587, fig|1198629.3.peg.349, fig|652611.13.peg.5573, fig|1163396.3.peg.5795, fig|1262663.10.peg.4443, fig|1295076.3.peg.4913, fig|1168061.3.peg.2799, fig|1315978.3.peg.358, fig|1093787.3.peg.5499, fig|6666666.7915.peg.5131, fig|1000561.3.peg.1639, fig|941193.4.peg.5426, fig|1131758.3.peg.3918, fig|1051005.3.peg.5901, fig|1163395.3.peg.5339, fig|557722.3.peg.5651, fig|1208103.3.peg.222, fig|1078464.3.peg.5274 596 615 yes 2137047 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471517 Prochlorococcus sp. scB245a_519O21 Bacteria 647671180 WP_025937699.1 453 456 yes 2137048 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408305 Butyrivibrio sp. LB2008 Bacteria 651403157 WP_026514728.1 434 435 yes 2137049 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28196 652411511 WP_026807174.1 448 450 yes 2137050 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1120792 Methylopila sp. 73B Bacteria 519028447 WP_020184322.1 613 619 yes 2137051 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 745717 Olleya sp. VCSA23 Bacteria 654837292 WP_028289993.1 619 619 yes 2137052 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444207 Escherichia coli, Escherichia coli 2-316-03_S4_C1 Bacteria UP000036210, UP000028021 727767271, 652093014 KDY08285.1 WP_033871373.1 626 631 yes 2137053 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 91623 Clostridium akagii Bacteria 652489555 WP_026884077.1 432 432 yes 2137054 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204042 Dickeya zeae Bacteria 654621089 WP_028085545.1 629 653 yes 2137055 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449044 Arthrobacter sp. UNC362MFTsu5.1 Bacteria 654818362 WP_028271657.1 594 628 yes 2137056 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 546, 1439318 Citrobacter freundii, Citrobacter freundii MGH 56 Bacteria UP000030582, UP000027564 757800824, 635729380 KDF11146.1 WP_043018025.1 626 632 yes 2137057 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 95486 Burkholderia cenocepacia Bacteria UP000065887 736021816, 653631113 KEA60526.1 WP_034186584.1 642 643 yes 2137058 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471522 Prochlorococcus sp. scB245a_520K10 Bacteria 647643157 WP_025915208.1 451 456 yes 2137059 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47879 Pseudomonas corrugata Bacteria 640015693 WP_024781424.1 fig|313612.3.peg.1692 628 629 yes 2137060 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 647055456 WP_025634594.1 636 636 yes 2137061 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397282 Pseudomonas sp. PH1b Bacteria 640707022 WP_025130441.1 628 629 yes 2137062 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 556 Erwinia chrysanthemi Bacteria UP000030389 654085292 WP_027713410.1 629 653 yes 2137063 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 231455 Dyella japonica Bacteria 651849427 WP_026634911.1 625 626 yes 2137064 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1716 648476195 WP_026167946.1 627 634 yes 2137065 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 160699 Agrobacterium larrymoorei Bacteria 653760211 WP_027676734.1 600 607 yes 2137066 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 523841 Haloferax mediterranei ATCC 33500 Archaea UP000011603 662859523, 640914242 AFK19884.2 YP_006349871.2 I3R6M4 I3R6M4_HALMT fig|290338.6.peg.234 457 488 yes 2137067 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1266914 Thioalkalivibrio sp. AKL19 Bacteria 636790673 WP_024326711.1 627 629 yes 2137068 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444044, 1444179, 1444219, 1444275, 1444041, 1444151 Escherichia coli, Escherichia coli 2-460-02_S1_C1, Escherichia coli 2-177-06_S3_C3, Escherichia coli 1-392-07_S4_C1, Escherichia coli 1-392-07_S4_C3, Escherichia coli 2-222-05_S1_C1, Escherichia coli 2-177-06_S3_C2 Bacteria UP000036210, UP000028038, UP000027864, UP000027703, UP000030114, UP000027812, UP000027743 693021230, 660338251, 660319017, 660307425, 660272433, 652046699, 652022951 KEO25485.1, KEO06950.1, KEN95807.1, KEN62730.1, KDX64293.1, KDX41877.1 WP_032199210.1 626 631 yes 2137069 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 259 Sphingobacterium thalpophilum Bacteria 654601381 WP_028068301.1 604 604 yes 2137070 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 647075880 WP_025638563.1 640 646 yes 2137071 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375 Bradyrhizobium japonicum Bacteria UP000030904 654679295 WP_028138122.1 623 632 yes 2137072 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1218 647650553 WP_025921654.1 452 456 yes 2137073 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 823, 1339343, 1339342 Parabacteroides distasonis, Parabacteroides distasonis str. 3776 D15 iv, Parabacteroides distasonis str. 3776 D15 i Bacteria UP000028028, UP000027850 738757460, 649566617, 649527575 KDS72752.1, KDS35102.1 WP_036650977.1 565 565 yes 2137074 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 506591 Phaeobacter caeruleus Bacteria 652984371 WP_027236960.1 596 604 yes 2137075 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1118055 Anaerococcus sp. PH9 Bacteria 648283841 WP_026064990.1 431 431 yes 2137076 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29449, 1432049, 1432050 Rhizobium etli, Rhizobium etli bv. phaseoli str. IE4803, Rhizobium etli bv. mimosae str. IE4771 Bacteria UP000031160, UP000027180 749200263, 744805669, 647796953 AJC83617.1, AIC31659.1 WP_040112910.1 603 610 yes 2137077 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1460647 Vibrio sp. JCM 19052 Bacteria UP000027062 641263587 fig|96561.3.peg.990 639 645 yes 2137078 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324 Stenotrophomonas maltophilia Bacteria UP000034806 647597556 WP_025874155.1 613 614 yes 2137079 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 653811876 WP_027691127.1 602 608 yes 2137080 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1370120 Mycobacterium sp. UM_WGJ Bacteria 638966064 WP_024440127.1 545 547 yes 2137081 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645921070 WP_025475055.1 454 465 yes 2137082 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 580026 Enterorhabdus mucosicola Bacteria 654560084 WP_028027439.1 434 435 yes 2137083 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 564 564 yes 2137084 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280665 Butyrivibrio sp. XPD2002 Bacteria 651381051 WP_026493192.1 434 434 yes 2137085 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471475 Prochlorococcus sp. scB243_495N3 Bacteria 647727150 WP_025976027.1 453 456 yes 2137086 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 823, 1339341 Parabacteroides distasonis, Parabacteroides distasonis str. 3776 Po2 i Bacteria UP000027861 738716492, 649546377 KDS53131.1 WP_036610908.1 565 565 yes 2137087 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444201 Escherichia coli, Escherichia coli 2-011-08_S4_C1 Bacteria UP000036210, UP000027827 692984851, 649977602 KDT03247.1 WP_032174335.1 626 631 yes 2137088 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 982 Cytophaga fermentans Bacteria 653273414 WP_027471348.1 424 424 yes 2137089 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471459 Prochlorococcus sp. scB241_528O2 Bacteria 647662170 WP_025931001.1 456 459 yes 2137090 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1850 Actinopolyspora halophila Bacteria 648460267 WP_026152018.1 550 560 yes 2137091 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 428 429 yes 2137092 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43305 Clostridium proteoclasticum Bacteria 651915806 WP_026663596.1 434 434 yes 2137093 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 270496 Desulfovibrio putealis Bacteria 652938135 WP_027191727.1 431 435 no 2137094 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298867 Bradyrhizobium sp. URHA0002 Bacteria 653443222 WP_027536229.1 629 639 yes 2137095 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2371 Xylella fastidiosa Bacteria UP000028529 653904025 WP_027700726.1 595 601 yes 2137096 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 639030 Acidobacteria bacterium KBS 146 Bacteria 651251943 WP_026386768.1 481 493 yes 2137097 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 319475 Clostridium lundense Bacteria 653613643 WP_027624117.1 437 437 yes 2137098 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280664 Butyrivibrio sp. VCD2006 Bacteria 651425334 WP_026527542.1 434 434 yes 2137099 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1502 Clostridium perfringens Bacteria UP000059070 647139476 WP_025648770.1 436 436 yes 2137100 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 489 Neisseria polysaccharea Bacteria 645196458 WP_025457444.1 625 633 yes 2137101 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1401256 Xylella fastidiosa MUL0034 Bacteria UP000027136 647814638 AIC12433.1 597 618 yes 2137102 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 358823 Streptomyces olindensis Bacteria UP000027206 664606102, 640935676 KDN78182.1 WP_031115222.1 fig|399741.3.peg.212 592 594 yes 2137103 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537 537 yes 2137104 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29448 Bradyrhizobium elkanii Bacteria UP000032215 654880790 WP_028332606.1 611 621 yes 2137105 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280672 Butyrivibrio sp. AC2005 Bacteria 651905133 WP_026658309.1 433 434 yes 2137106 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 469 640670771 WP_025095815.1 fig|402882.10.peg.3792 627 631 yes 2137107 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 64970 Marinobacterium jannaschii Bacteria 654377083 WP_027856102.1 625 626 yes 2137108 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 627 639 yes 2137109 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1054037 Sphingobium sp. KK22 Bacteria UP000054322 646530497 WP_025551005.1 611 619 yes 2137110 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397276 Bacillus sp. H1a Bacteria 640725126 WP_025148161.1 586 586 yes 2137111 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1487711 Streptomyces sp. NTK 937 Bacteria UP000027475 740028519, 646541191 KDQ68398.1 WP_037878176.1 593 622 yes 2137112 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 944481 Hippea sp. KM1 Bacteria 643957541 WP_025270171.1 428 428 yes 2137113 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1305837 Streptomyces sp. CNS606 Bacteria 654250041 WP_027765530.1 606 608 yes 2137114 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 165695, 1450518 Sphingobium lucknowense F2 Bacteria UP000028135 640738961, 663087493 KER36077.1 WP_025161211.1 611 619 yes 2137115 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68287 640487771 WP_024927591.1 fig|379731.4.peg.1832 596 611 yes 2137116 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 434 443 no 2137117 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397275 Alcaligenes sp. DH1f Bacteria 640715145 WP_025138395.1 636 637 yes 2137118 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 647026009 WP_025629371.1 640 646 yes 2137119 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1200557 Anaerovibrio sp. RM50 Bacteria 653156577 WP_027405590.1 436 437 yes 2137120 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 588932 Brevundimonas sp. BIO-TAS2-2 Bacteria 636828496 WP_024354545.1 619 635 yes 2137121 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 654673621 WP_028132593.1 626 631 yes 2137122 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 323450 Pontibacter actiniarum Bacteria 646889073 WP_025609278.1 620 620 yes 2137123 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1402 Bacillus licheniformis Bacteria UP000036721 647504480 WP_025811876.1 591 591 yes 2137124 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646462898 WP_025536577.1 640 646 yes 2137125 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265470 Desulfurispora thermophila Bacteria 648485185 WP_026176936.1 417 426 yes 2137126 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29536 Flavobacterium succinicans Bacteria 640548250 WP_024980367.1 fig|351605.4.peg.742 614 614 yes 2137127 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 456299 Chryseobacterium gregarium Bacteria 653137626 WP_027386967.1 603 603 yes 2137128 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1492281 alpha proteobacterium Q-1 Bacteria UP000027360 754709847, 654636059 WP_042084852.1 612 616 yes 2137129 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470 Acinetobacter baumannii Bacteria UP000028632 638876757 WP_024434306.1 fig|331978.3.peg.3284, fig|1290412.3.peg.5168 621 625 yes 2137130 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54311 Spirulina subsalsa Bacteria 648318658 WP_026079731.1 459 459 yes 2137131 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 971 Selenomonas ruminantium Bacteria 652369218 WP_026765242.1 437 437 yes 2137132 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298861 Lysobacter sp. URHA0019 Bacteria 652772025 WP_027083752.1 623 624 yes 2137133 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 376489 Halotalea alkalilenta Bacteria 653101822 WP_027351905.1 631 640 yes 2137134 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392493 Lachnospiraceae bacterium AC2031 Bacteria 653227376 WP_027439875.1 427 427 yes 2137135 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1495854 Brevundimonas sp. EAKA Bacteria UP000027434 646091670 KDP93795.1 617 621 yes 2137136 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46680 Pseudomonas nitroreducens Bacteria 639929288 WP_024764298.1 fig|399741.3.peg.3973 626 626 yes 2137137 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 146938 Azovibrio restrictus Bacteria 651966674 WP_026686983.1 638 638 yes 2137138 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646417197 WP_025526458.1 640 646 yes 2137139 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 329858 Cohnella thermotolerans Bacteria 652786179 WP_027091651.1 586 587 yes 2137140 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1496722 Butyrivibrio sp. AE2005 Bacteria 651924243 WP_026667237.1 434 435 yes 2137141 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1137271 Saccharomonospora sp. CNQ490 Bacteria 640356166 WP_024875274.1 543 545 yes 2137142 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646580195 WP_025559121.1 640 646 yes 2137143 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298879 Streptomyces sp. CNQ329 Bacteria 654258691 WP_027774031.1 591 593 yes 2137144 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1283292 Pseudomonas sp. URMO17WK12:I4 Bacteria 654437991 WP_027908622.1 627 628 yes 2137145 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471446 Prochlorococcus sp. scB241_527G5 Bacteria 647701581 WP_025959206.1 453 456 yes 2137146 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646362614 WP_025505661.1 640 646 yes 2137147 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 944435 Burkholderia sp. WSM2230 Bacteria 646846454 WP_025598822.1 642 643 yes 2137148 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 621 662 yes 2137149 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 49338 Desulfitobacterium hafniense Bacteria UP000054623 648492250 WP_026184001.1 428 432 yes 2137150 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 449 450 yes 2137151 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 384 Rhizobium leguminosarum Bacteria 653794869 WP_027686790.1 600 607 yes 2137152 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1211115 Chelatococcus sp. GW1 Bacteria 648233733 WP_026014882.1 607 608 yes 2137153 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 122960 Alicyclobacillus herbarius Bacteria 652567603 WP_026961024.1 583 585 yes 2137154 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1491 Clostridium botulinum Bacteria UP000030128 647364992 WP_025775977.1 437 437 yes 2137155 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1150775 Agrobacterium sp. 10MFCol1.1 Bacteria 648639158 WP_026330909.1 599 607 yes 2137156 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 598 604 yes 2137157 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444080, 1444085 Escherichia coli, Escherichia coli 1-250-04_S1_C2, Escherichia coli 3-267-03_S1_C2 Bacteria UP000036210, UP000027639, UP000028133 727763119, 652005559, 650076505 KDX25399.1, KDT98391.1 WP_033868215.1 626 631 yes 2137158 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645917471 WP_025471456.1 426 437 yes 2137159 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA fig|10116.3.peg.1261 595 601 yes 2137160 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28139 Rikenella microfusus Bacteria 653038997 WP_027290682.1 513 514 yes 2137161 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 440 444 yes 2137162 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1288079 Streptomyces sp. CNT318 Bacteria 654244307 WP_027759918.1 602 604 yes 2137163 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 267989 640062353 WP_024787082.1 461 461 yes 2137164 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1259798 Pseudomonas sp. LAMO17WK12:I2 Bacteria 653592018 WP_027604923.1 628 634 yes 2137165 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 134 Methylocystis parvus Bacteria 515487857 WP_016921125.1 609 609 yes 2137166 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 646702318 WP_025570999.1 640 646 yes 2137167 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1033 639251591 WP_024576403.1 fig|693973.4.peg.3293, fig|399599.3.peg.4518, fig|402882.10.peg.4544 634 643 yes 2137168 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 613 640697496 WP_025121560.1 633 647 yes 2137169 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76745 Sinorhizobium arboris Bacteria 654530232 WP_027998323.1 601 611 yes 2137170 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 617 yes 2137171 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1224318 Mangrovibacter sp. MFB070 Bacteria UP000027726 738145580, 653405595 KEA54343.1 WP_036103030.1 625 631 yes 2137172 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 225762 Nocardiopsis alkaliphila Bacteria 648425849 WP_026117600.1 541 542 yes 2137173 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1460635 Geomicrobium sp. JCM 19038 Bacteria UP000027014 636721044 554 554 yes 2137174 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375 Bradyrhizobium japonicum Bacteria UP000030904 636813312 WP_024339490.1 623 632 yes 2137175 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423 Bacillus subtilis Bacteria UP000030083 639242443 WP_024572627.1 fig|316274.7.peg.3070 590 590 yes 2137176 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1471461 Prochlorococcus sp. scB241_528P18 Bacteria 647723176 WP_025973574.1 453 456 yes 2137177 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28080 Campylobacter upsaliensis Bacteria 653052412 WP_027303975.1 432 432 yes 2137178 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537 537 yes 2137179 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 525 Acidocella facilis Bacteria 651316010 WP_026440656.1 602 606 yes 2137180 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935840 Chelativorans sp. J32 Bacteria 654567984 WP_028035249.1 600 603 yes 2137181 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 990370 Pseudogulbenkiania sp. MAI-1 Bacteria 635657696 WP_024304563.1 635 636 yes 2137182 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1540 Clostridium mangenotii Bacteria 654051828 WP_027702963.1 432 433 yes 2137183 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 627 628 yes 2137184 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1296415 Aquimarina sp. SW150 Bacteria 647298690 WP_025742755.1 619 619 yes 2137185 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 115781 Desulfotignum balticum Bacteria 636810121 WP_024336319.1 422 434 no 2137186 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1460648 Vibrio sp. JCM 19053 Bacteria UP000027110 636733917 637 643 yes 2137187 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 639504111 WP_024673638.1 627 629 yes 2137188 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1520 Clostridium beijerinckii Bacteria UP000031866 652491406 WP_026885920.1 436 436 yes 2137189 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1211851 Dyadobacter sp. Y620-1 Bacteria 647326968 WP_025761861.1 620 620 yes 2137190 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54265 Carboxydothermus ferrireducens Bacteria 654584364 WP_028051464.1 429 429 yes 2137191 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265477 Desulfotomaculum alcoholivorax Bacteria 653115950 WP_027365542.1 430 431 yes 2137192 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375 Bradyrhizobium japonicum Bacteria UP000030904 654720456 WP_028178058.1 623 642 yes 2137193 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 173 Leptospira interrogans Bacteria UP000037872 642963671 WP_025176734.1 298 298 no 2137194 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 459527 Saccharibacillus kuerlensis Bacteria 648602173 WP_026293924.1 580 580 yes 2137195 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 648581099 WP_026272850.1 537 537 yes 2137196 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 266762 Porphyromonas gingivicanis Bacteria UP000030134 647564494 WP_025842970.1 589 589 yes 2137197 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 823, 1339345, 1339344 Parabacteroides distasonis, Parabacteroides distasonis str. 3999B T(B) 6, Parabacteroides distasonis str. 3999B T(B) 4 Bacteria UP000028039, UP000028056 738737441, 649562076, 649561278 KDS68301.1, KDS67550.1 WP_036631448.1 565 565 yes 2137198 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1465766 Paenibacillus senegalensis Bacteria 648240165 WP_026021314.1 582 582 yes 2137199 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 639 639 yes 2137200 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471456 Prochlorococcus sp. scB241_528N17 Bacteria 647683787 WP_025946510.1 363 365 no 2137201 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1305734 Polaromonas sp. EUR3 1.2.1 Bacteria 652385753 WP_026781681.1 638 639 yes 2137202 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571254 Ochrobactrum rhizosphaerae Bacteria 640421670 WP_024899785.1 597 601 yes 2137203 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444150 Escherichia coli, Escherichia coli 2-156-04_S3_C2 Bacteria UP000036210, UP000027711 692998577, 651750710 KDW28837.1 WP_032185272.1 626 631 yes 2137204 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444251 Escherichia coli, Escherichia coli 3-267-03_S4_C2 Bacteria UP000036210, UP000027722 693096010, 650101709 KDU22481.1 WP_032252805.1 626 631 yes 2137205 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1136433 Streptomyces sp. CNT371 Bacteria 654211903 WP_027741572.1 598 602 yes 2137206 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 582 Morganella morganii Bacteria UP000037663 640731722 WP_025154574.1 620 649 yes 2137207 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1238, 1227812 Piscirickettsia salmonis, Piscirickettsia salmonis LF-89 = ATCC VR-1361 Bacteria UP000065118, UP000037680 652990134, 838100025, 701642890 KLV36324.1, KGP95164.1 WP_027242686.1 623 627 yes 2137208 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 306546 Marinimicrobium agarilyticum Bacteria 653078881 WP_027329470.1 629 631 yes 2137209 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84480 Amycolatopsis thermoflava Bacteria 654463372 WP_027933783.1 542 544 yes 2137210 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1407650 Synechococcus sp. NKBG15041c Bacteria 639206360 WP_024544628.1 459 461 yes 2137211 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 95486 Burkholderia cenocepacia Bacteria UP000065887 654292740 WP_027807506.1 642 643 yes 2137212 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 86664 Bacillus flexus Bacteria 647315199 WP_025753250.1 589 589 yes 2137213 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39645 Mesorhizobium ciceri Bacteria 639164409 WP_024504262.1 596 611 yes 2137214 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 150060 Halonatronum saccharophilum Bacteria 653090457 WP_027340694.1 427 427 yes 2137215 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 404770 Marinobacterium litorale Bacteria 654376201 WP_027855339.1 626 628 yes 2137216 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 31962 Actinomadura cremea subsp. rifamycini Bacteria 651273001 WP_026406123.1 573 577 yes 2137217 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 939637 gamma proteobacterium SCGC AAA003-E02 Bacteria 646630926 WP_025566447.1 628 628 yes 2137218 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630403 Tomitella biformata Bacteria 640113998 WP_024795820.1 fig|349101.6.peg.3658 545 549 yes 2137219 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76594, 1348585 Cellulophaga baltica, Cellulophaga baltica NN016038 Bacteria UP000030303 646938224, 723620250 AIY13622.1 WP_025614515.1 619 619 yes 2137220 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410632 Lachnospiraceae bacterium V9D3004 Bacteria 652811828 WP_027104186.1 434 435 yes 2137221 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 75922 Mycobacterium tusciae Bacteria 653081328 WP_027331887.1 516 519 yes 2137222 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 645917923 WP_025471908.1 442 454 yes 2137223 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 570 584 yes 2137224 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 123899 Bordetella trematum Bacteria 646373596 WP_025513943.1 636 637 yes 2137225 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 189753 Bradyrhizobium sp. Ec3.3 Bacteria 653409910 WP_027522398.1 623 632 yes 2137226 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1795 Mycobacterium neoaurum Bacteria UP000033686 662769589, 642753983 WP_030134172.1 fig|314275.3.peg.3942, fig|1004786.3.peg.524 510 522 yes 2137227 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 281920 Porphyromonas uenonis Bacteria 647607400 WP_025883294.1 590 590 yes 2137228 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 79264 Paenibacillus ehimensis Bacteria 647572431 WP_025850570.1 594 594 yes 2137229 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 218208 Desulfatibacillum aliphaticivorans Bacteria 654861657 WP_028313973.1 437 438 yes 2137230 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 443598 Bradyrhizobium sp. Cp5.3 Bacteria 653492442 WP_027556840.1 623 632 yes 2137231 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65497 Actinoalloteichus cyanogriseus Bacteria 651285607 WP_026417559.1 543 554 yes 2137232 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 408558 Comamonas composti Bacteria 652653603 WP_027014969.1 625 644 yes 2137233 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1485002, 106649 Acinetobacter sp. ETR1, Acinetobacter guillouiae Bacteria UP000027773 736603959, 654405749, 674997700 KEC85052.1 WP_034612636.1 626 631 yes 2137234 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1218 647621302 WP_025895095.1 453 456 yes 2137235 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 196588 Porphyrobacter cryptus Bacteria 653236908 WP_027442628.1 623 631 yes 2137236 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 551788 Caldicoprobacter oshimai Bacteria 647307553 WP_025747630.1 426 426 yes 2137237 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 485 Neisseria gonorrhoeae Bacteria UP000027314 728044743, 693765830, 654607096 KGI96691.1, KEC87588.1 WP_033910638.1 624 633 yes 2137238 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 386056 Burkholderia ferrariae Bacteria 654769835 WP_028224351.1 647 648 yes 2137239 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 279356 Aquimarina muelleri Bacteria 653169781 WP_027412920.1 619 619 yes 2137240 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543 639220998 WP_024558456.1 626 632 yes 2137241 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487 Neisseria meningitidis Bacteria UP000050419 645176939 WP_025455703.1 625 633 yes 2137242 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1167732 Bacillus sp. JGI 001011-F15 Bacteria 647218086 WP_025672085.1 592 592 yes 2137243 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1402 Bacillus licheniformis Bacteria UP000036721 647494782 WP_025807986.1 591 591 yes 2137244 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1365007 Psychromonas sp. SP041 Bacteria 646612418 WP_025563167.1 646 664 yes 2137245 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204470 Alicyclobacillus pomorum Bacteria 652571393 WP_026964749.1 592 592 yes 2137246 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44676 Geothrix fermentans Bacteria 652458509 WP_026853335.1 605 609 yes 2242493 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67385 Streptomyces xanthophaeus Bacteria 665550947 WP_031141348.1 593 595 yes 2242494 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 321661 Pseudomonas vranovensis Bacteria 655598720 WP_028945647.1 628 629 yes 2242495 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449966 Enterobacter sp. T1-1 Bacteria 659669394 WP_029883064.1 626 631 yes 2242496 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1307759 Desulfovibrio alkalitolerans L21-Syr-AB Bacteria 659846363 WP_029893908.1 409 421 no 2242497 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463822 Kitasatospora sp. NRRL B-11411 Bacteria 663675802 WP_030459567.1 591 593 yes 2242498 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 658936619 WP_029795987.1 640 646 yes 2242499 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 664570216 WP_031084698.1 592 607 yes 2242500 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1130318 euryarchaeote SCGC AAA261-G15 Archaea 656263410 WP_029209364.1 281 281 no 2242501 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39960 Erythrobacter litoralis Bacteria UP000027866 736907748, 660650206 KEO89939.1 WP_034906197.1 620 626 yes 2242502 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449049 Caulobacter sp. UNC358MFTsu5.1 Bacteria 659869804 WP_029916672.1 612 612 3EPM, 3EPO, 3EPN, 4S2A yes 2242503 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1432325 Candidatus Aminicenans sakinawicola Bacteria 655034459 WP_028483245.1 434 435 yes 2242504 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53413, 325777 Xanthomonas axonopodis, Xanthomonas axonopodis pv. vasculorum Bacteria UP000054035, UP000028012 757567798, 689491330 KGE51258.1 WP_042823597.1 624 625 yes 2242505 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1112272 Hyphomicrobium sp. 802 Bacteria 658445098 WP_029670866.1 603 605 yes 2242506 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1911 Streptomyces griseus Bacteria UP000032367 664162153 WP_030696657.1 596 597 yes 2242507 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 594 609 yes 2242508 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 86661, 1396 Bacillus cereus Bacteria UP000036076 657630335, 663081521 AIE81688.1 WP_029441018.1 586 586 yes 2242509 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1713 Oerskovia turbata Bacteria 663109983 WP_030151089.1 556 564 yes 2242510 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1836 Saccharopolyspora erythraea Bacteria 665968585 WP_031334546.1 539 540 yes 2242511 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 399, 1028801 Rhizobium galegae, Rhizobium galegae bv. officinalis str. HAMBI 1141 Bacteria UP000028186 740761796, 659663154 WP_038547080.1 600 603 yes 2242512 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351671 Xenorhabdus doucetiae Bacteria UP000032721 800944663, 661562974 WP_045972939.1 625 658 yes 2242513 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816 Bifidobacterium longum Bacteria UP000028505 658455051 WP_029680461.1 634 917 yes 2242514 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33942 Brevibacillus thermoruber Bacteria 656062352 WP_029100146.1 591 593 yes 2242515 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3656 Cucumis melo Plants 659115105 XP_008457389.1 550 1067 yes 2242516 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1169152 Nocardia sp. CNY236 Bacteria 655030163 WP_028479025.1 165 477 no 2242517 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 122 133 no 2242518 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168697 Salinispora arenicola Bacteria 655978575 WP_029020871.1 530 530 yes 2242519 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 153496 Kozakia baliensis Bacteria 657901218 WP_029604198.1 612 641 yes 2242520 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1760 663128373 WP_030169248.1 544 546 yes 2242521 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463886 Streptomyces sp. NRRL S-15 Bacteria 664576232 WP_031090310.1 604 631 yes 2242522 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37637 Corynebacterium pseudodiphtheriticum Bacteria 665901349 WP_031268218.1 603 610 yes 2242523 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265 Ruminococcus flavefaciens Bacteria 655073112 WP_028521315.1 437 437 yes 2242524 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 774, 1293906 Bartonella bacilliformis, Bartonella bacilliformis Cond044 Bacteria UP000059456, UP000031738 757775775, 657175210 KEG16542.1 WP_042994807.1 601 610 yes 2242525 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456256 uncultured marine thaumarchaeote KM3_70_F07 Archaea 663525444 AIF15645.1 A0A075HK66 A0A075HK66_9ARCH 442 442 yes 2242526 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1911 Streptomyces griseus Bacteria UP000032367 664220965 WP_030753943.1 596 598 yes 2242527 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444116 Escherichia coli, Escherichia coli 6-537-08_S1_C3 Bacteria UP000036210, UP000028151 693052023, 660259746 KEN50297.1 WP_032220921.1 626 631 yes 2242528 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 475254 Pedobacter borealis Bacteria 657034685 WP_029277982.1 627 627 yes 2242529 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1740, 289377 Thermodesulfobacterium commune DSM 2178 Bacteria UP000028481 655458490, 668352215 AIH04429.1 WP_028841520.1 433 436 yes 2242530 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 574375 Bacillus sp. BL3-6 Bacteria UP000027778 727212018, 659911688 KEK25412.1 WP_033673264.1 586 586 yes 2242531 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1489678 Deinococcus sp. RL Bacteria UP000027898 656340490 KEF33488.1 584 598 yes 2242532 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 281714 Nocardioides alkalitolerans Bacteria 655024485 WP_028473391.1 559 573 yes 2242533 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305 Ralstonia solanacearum Bacteria UP000029286 515093359 WP_016722572.1 629 631 yes 2242534 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 73044 Streptomyces seoulensis Bacteria 665634354 WP_031179115.1 595 601 yes 2242535 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 936134 Ensifer sp. USDA 6670 Bacteria 661265378 WP_029960070.1 601 611 yes 2242536 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1886 Streptomyces albidoflavus Bacteria 663306869 WP_030307479.1 595 597 yes 2242537 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463916 Streptomyces sp. NRRL S-623 Bacteria 665519939 WP_031122569.1 592 600 yes 2242538 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463859 Streptomyces sp. NRRL F-5140 Bacteria 664428290 WP_030952866.1 594 600 yes 2242539 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1491, 1443125 Clostridium botulinum, Clostridium botulinum C/D str. BKT12695 Bacteria UP000030128, UP000027789 746235802, 658083296 KEH96217.1 WP_039284370.1 437 437 yes 2242540 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 646 660 yes 2242541 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935849 Paracoccus sp. J55 Bacteria 655303412 WP_028712139.1 592 599 yes 2242542 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 485 Neisseria gonorrhoeae Bacteria UP000027314 658446135 WP_029671889.1 622 624 yes 2242543 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1333998 alpha proteobacterium MA2 Bacteria UP000028702 780043498, 665493672 WP_045449040.1 601 614 yes 2242544 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 90814 Thiomicrospira sp. Milos-T2 Bacteria 657350814 WP_029407494.1 641 647 yes 2242545 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 292 Burkholderia cepacia Bacteria UP000063625 759460808, 663476714 KER71399.1 WP_043182138.1 642 643 yes 2242546 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386 657870831 WP_029575422.1 586 586 yes 2242547 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280674 Prevotella sp. AGR2160 Bacteria 655536165 WP_028908949.1 521 521 yes 2242548 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406 Paenibacillus polymyxa Bacteria UP000031922 657718995 WP_029515777.1 422 422 yes 2242549 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 659035720 WP_029855306.1 640 646 yes 2242550 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470866 Salinimicrobium terrae Bacteria 655993126 WP_029034757.1 618 618 yes 2242551 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 663149204 WP_030189035.1 589 591 yes 2242552 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1823 Nocardia otitidiscaviarum Bacteria 659886285 WP_029932977.1 540 541 yes 2242553 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67255 Streptomyces achromogenes Bacteria 664076489 WP_030615045.1 593 594 yes 2242554 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1047017 candidate division OP8 bacterium SCGC AAA252-D18 Bacteria 656196175 WP_029155487.1 198 198 no 2242555 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463855 Streptomyces sp. NRRL F-5065 Bacteria 663425235 WP_030420091.1 604 612 yes 2242556 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 592 622 yes 2242557 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1137280 Marinobacter sp. AK21 Bacteria UP000035057 656104068 KEF29763.1 624 626 yes 2242558 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1232442 Clostridiales bacterium VE202-06 Bacteria 657668514 WP_029471426.1 435 435 yes 2242559 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47872 Micromonospora purpureochromogenes Bacteria 663725210 WP_030501587.1 534 534 yes 2242560 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463919 Streptomyces sp. NRRL S-813 Bacteria 663127740 WP_030168617.1 593 594 yes 2242561 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 189691 Paenibacillus elgii Bacteria 656244583 WP_029191213.1 595 595 yes 2242562 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1112274 Methylophilus sp. 5 Bacteria 656167539 WP_029147745.1 625 631 yes 2242563 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66897 Streptomyces griseorubens Bacteria UP000027632 739788509, 657285352 KEG41259.1 WP_037640569.1 595 598 yes 2242564 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 419 419 yes 2242565 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285 Comamonas testosteroni Bacteria UP000029609 656209305 WP_029158747.1 625 644 yes 2242566 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 905826, 1502289, 1503183, 1502291, 1502292 Marine Group I thaumarchaeote SCGC AAA799-B03, Marine Group I thaumarchaeote RSA3, Marine Group I thaumarchaeote SCGC AAA799-D11, Marine Group I thaumarchaeote SCGC AAA799-E16 Archaea UP000029386, UP000028027 851100867, 675348722, 675345664, 675343904, 662557435 KFM21526.1, KFM18633.1, KFM16942.1, KER06034.1 WP_048069509.1 A0A087RYS9, A0A087S722, A0A087RTY8, A0A081S531 A0A087RYS9_9ARCH, A0A087S722_9ARCH, A0A087RTY8_9ARCH, A0A081S531_9ARCH 442 442 yes 2242567 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1823 Nocardia otitidiscaviarum Bacteria 659876760 WP_029923530.1 413 428 no 2242568 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463897 Streptomyces sp. NRRL S-244 Bacteria 663112156 WP_030153247.1 593 595 yes 2242569 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1121097 Bacteroides graminisolvens DSM 19988 Bacteria UP000027601 665398523 246 247 no 2242570 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1121097 Bacteroides graminisolvens DSM 19988 Bacteria UP000027601 665398522 60 70 no 2242571 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1121097 Bacteroides graminisolvens DSM 19988 Bacteria UP000027601 665398521 183 183 no 2242572 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 662172106 WP_030115077.1 589 591 yes 2242573 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463938 Streptomyces sp. NRRL WC-3795 Bacteria 664498604 WP_031017624.1 600 603 yes 2242574 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53246 655451086 WP_028834526.1 646 650 yes 2242575 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 301953 Caldicellulosiruptor acetigenus Bacteria 656282065 WP_029227717.1 418 420 yes 2242576 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 592 622 yes 2242577 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471467 Prochlorococcus sp. scB241_529J16 Bacteria 661285151 WP_029978242.1 93 93 no 2242578 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 619 yes 2242579 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 400634, 28031, 1571920 Lysinibacillus fusiformis, Lysinibacillus sp. A1 Bacteria UP000029429, UP000030963 738165235, 756122063, 733376794 AJK89753.1, KHK51810.1 WP_036122290.1 592 592 yes 2242580 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68253 Streptomyces peruviensis Bacteria 662089162 WP_030048436.1 598 600 yes 2242581 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 659021728 WP_029848681.1 640 646 yes 2242582 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 663411236 WP_030406691.1 592 593 yes 2242583 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471456 Prochlorococcus sp. scB241_528N17 Bacteria 661283416 WP_029976561.1 93 94 no 2242584 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55601 Listonella anguillarum Bacteria UP000030318 657302617 WP_029388211.1 640 649 yes 2242585 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 265429 Silanimonas lenta Bacteria 655364449 WP_028770526.1 624 626 yes 2242586 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1437453 Streptomyces sp. C34(2013) Bacteria UP000037274 657295915, 822879315 WP_029382036.1 593 597 yes 2242587 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 418856 Nevskia soli Bacteria 659872282 WP_029919139.1 627 628 yes 2242588 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444114 Escherichia coli, Escherichia coli 6-175-07_S1_C3 Bacteria UP000036210, UP000028111 727764439, 660155770 KEM49113.1 WP_033869147.1 626 631 yes 2242589 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 657061966 WP_029304446.1 645 663 yes 2242590 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463905 Streptomyces sp. NRRL S-384 Bacteria 664379410 WP_030906073.1 591 593 yes 2242591 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 594 601 yes 2242592 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463910 Streptomyces sp. NRRL S-475 Bacteria 664321264 WP_030850000.1 592 594 yes 2242593 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444130 Escherichia coli, Escherichia coli 7-233-03_S3_C1 Bacteria UP000036210, UP000027785 693157309, 660175849 KEM68646.1 WP_032293371.1 626 631 yes 2242594 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 407019 Sphingomonas astaxanthinifaciens Bacteria 659894947 WP_029941620.1 624 630 yes 2242595 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 658956840, 778226637 KJR21479.1 WP_029807294.1 640 646 yes 2242596 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1350366 Thermoanaerobacter sp. A7A Bacteria 658480943 WP_029689291.1 431 432 yes 2242597 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 589873 Alteromonas sp. H17 Bacteria UP000066442 763175834, 666080805 AIF97298.1 WP_044055481.1 627 633 yes 2242598 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471530 Prochlorococcus sp. scB245a_521N5 Bacteria 661291522 WP_029984601.1 118 119 no 2242599 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471530 Prochlorococcus sp. scB245a_521N5 Bacteria 661291524 WP_029984603.1 91 92 no 2242600 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 203471 Tepidiphilus margaritifer Bacteria 655492518 WP_028873928.1 637 638 yes 2242601 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 656099228 WP_029127892.1 537 537 yes 2242602 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463874 Streptomyces sp. NRRL F-6131 Bacteria 663304879 WP_030305506.1 602 610 yes 2242603 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 300825, 1246626 Bacillus lehensis, Bacillus lehensis G1 Bacteria UP000027142 740694355, 655552498 AIC94362.1 WP_038479644.1 591 591 yes 2242604 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34086, 1358423 Sphingobacterium antarcticum, Sphingobacterium antarcticus 4BY Bacteria UP000028007 739586445, 662329538 KEQ28364.1 WP_037444192.1 627 627 yes 2242605 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1583098 Fusobacterium hwasookii Bacteria 657694825 WP_029494384.1 433 433 yes 2242606 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68237 Streptomyces mediolani Bacteria 664277051 WP_030807233.1 593 596 yes 2242607 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 38322 Thermotoga elfii Bacteria 655460750 WP_028843730.1 424 424 yes 2242608 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1288782 Vibrio parahaemolyticus, Vibrio parahaemolyticus VP766 Bacteria UP000028114, UP000032406 659038542, 758016427 KIT28322.1 WP_029857254.1 640 646 yes 2242609 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1166158, 1604132 Methylobacterium sp. L2-4, Methylobacterium sp. ME121 Bacteria UP000032904 657246587, 767164171 WP_029357729.1 622 628 yes 2242610 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1927 Streptomyces rimosus Bacteria UP000028432 757575923, 655936277 KEF20934.1 WP_042830059.1 590 593 yes 2242611 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35751 Sporichthya polymorpha Bacteria 655914499 WP_028984614.1 590 594 yes 2242612 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1499968 Paenibacillus sp. TCA20 Bacteria UP000028160 665414587 596 603 yes 2242613 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285574 Streptomyces erythrochromogenes Bacteria 665577725 WP_031156103.1 593 595 yes 2242614 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463880 Streptomyces sp. NRRL S-1022 Bacteria 663345378 WP_030344433.1 592 594 yes 2242615 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37326 Nocardia brasiliensis Bacteria 659845642 WP_029893200.1 547 549 yes 2242616 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406 Paenibacillus polymyxa Bacteria UP000031922 746221424, 660639006 KEO79922.1 WP_039270659.1 593 614 yes 2242617 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 284042 Streptomyces violaceorubidus Bacteria 663149181 WP_030189016.1 601 614 yes 2242618 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463896 Streptomyces sp. NRRL S-241 Bacteria 663387983 WP_030383962.1 592 594 yes 2242619 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1288083 Streptomyces sp. TAA040 Bacteria 654977846 WP_028427440.1 590 591 yes 2242620 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449059 Mycobacterium sp. UNC410CL29Cvi84 Bacteria 656090403 WP_029121373.1 536 540 yes 2242621 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 533 536 yes 2242622 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 215690 Thermomonas fusca Bacteria 655456929 WP_028840006.1 600 606 yes 2242623 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47716 Streptomyces olivaceus Bacteria 664520086 WP_031036677.1 591 593 yes 2242624 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67315 Streptomyces lavenduligriseus Bacteria 664254782 WP_030786263.1 593 594 yes 2242625 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463821 Glycomyces sp. NRRL B-16210 Bacteria 663116602 WP_030157593.1 527 530 yes 2242626 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 221 456 no 2242627 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 658959883 WP_029808516.1 636 636 yes 2242628 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1379281 Desulfonauticus sp. A7A Bacteria 661274216 WP_029968271.1 419 421 yes 2242629 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1047017 candidate division OP8 bacterium SCGC AAA252-D18 Bacteria 660519050 WP_029945837.1 267 268 no 2242630 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 257003 Sphingomonas phyllosphaerae Bacteria 655880283 WP_028967450.1 608 615 yes 2242631 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66875 Streptomyces catenulae Bacteria 663275548 WP_030289111.1 591 597 yes 2242632 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 915099 Pseudomonas sp. 2-92(2010) Bacteria 655188243 WP_028615491.1 627 629 yes 2242633 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 658993918 WP_029830863.1 640 646 yes 2242634 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670, 1288792 Vibrio parahaemolyticus, Vibrio parahaemolyticus 901128 Bacteria UP000028114, UP000032106 659053494, 758043315 KIT52823.1 WP_029864403.1 640 646 yes 2242635 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 426716 Nocardia rhamnosiphila Bacteria 663748854 WP_030524687.1 539 542 yes 2242636 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29350 Thermoanaerobacter thermocopriae Bacteria UP000053884 655944434 WP_028992534.1 431 432 yes 2242637 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1823 Nocardia otitidiscaviarum Bacteria 659877077 WP_029923843.1 413 428 no 2242638 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444220 Escherichia coli, Escherichia coli 3-020-07_S4_C1 Bacteria UP000036210, UP000028140 693121115, 658712141 KEJ54048.1 WP_032270093.1 626 631 yes 2242639 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 657059135 WP_029301806.1 650 667 yes 2242640 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1455882 uncultured marine thaumarchaeote AD1000_04_G03 Archaea 663499627 AIE90547.1 A0A075FLF8 A0A075FLF8_9ARCH 450 452 yes 2242641 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 561 565 yes 2242642 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397533 Marinobacter sp. EN3 Bacteria UP000017083 665843105 WP_031211222.1 622 625 yes 2242643 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 281091 Azorhizobium doebereinerae Bacteria 655960379 WP_029003135.1 609 618 yes 2242644 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444089 Escherichia coli, Escherichia coli 6-175-07_S1_C2 Bacteria UP000036210, UP000027842 693237162, 658661232 KEJ05557.1 WP_032347411.1 626 631 yes 2242645 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47863 Micromonospora globosa Bacteria 663233048 WP_030269362.1 537 537 yes 2242646 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33069 Pseudomonas viridiflava Bacteria UP000049942 656310577 WP_029243023.1 627 629 yes 2242647 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 619 yes 2242648 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36809 Mycobacterium abscessus Bacteria UP000046141 662145332 WP_030096289.1 542 543 yes 2242649 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1905 Streptomyces exfoliatus Bacteria 663987729 WP_030549728.1 593 595 yes 2242650 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 1457183 Bifidobacterium longum, Bifidobacterium longum subsp. infantis EK3 Bacteria UP000028505, UP000028416 695831854, 665776278 KEY26103.1 WP_032745309.1 635 917 yes 2242651 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1491, 1443128, 1443116, 1443127, 1443124 Clostridium botulinum, Clostridium botulinum C/D str. DC5, Clostridium botulinum D str. CCUG 7971, Clostridium botulinum C/D str. BKT2873, Clostridium botulinum C/D str. BKT75002 Bacteria UP000030128, UP000030014, UP000030005, UP000027622, UP000027740 746200557, 699759849, 699754525, 658098935, 658088294 KGM99031.1, KGM94019.1, KEI11169.1, KEI01003.1 WP_039257984.1 437 437 yes 2242652 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444101 Escherichia coli, Escherichia coli 5-172-05_S1_C3 Bacteria UP000036210, UP000027774 693163620, 660070034 KEL65735.1 WP_032298056.1 626 631 yes 2242653 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686276678, 655658523, 655654838 KED54629.1, KED51427.1 WP_031854669.1 640 646 yes 2242654 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380386 Mycobacterium sp. URHB0044 Bacteria 656087163 WP_029118162.1 529 531 yes 2242655 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 669 Vibrio harveyi Bacteria UP000067422 658927423 WP_029789256.1 640 646 yes 2242656 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935852 Pseudoxanthomonas sp. J35 Bacteria 655563122 WP_028916918.1 625 630 yes 2242657 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463833 Streptomyces sp. NRRL B-24484 Bacteria 663233693 WP_030270002.1 600 605 yes 2242658 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543 544 yes 2242659 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68170 Lechevalieria aerocolonigenes Bacteria UP000033393 663693874 WP_030470926.1 547 551 yes 2242660 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1927 Streptomyces rimosus Bacteria UP000028432 664095775 WP_030633719.1 591 593 yes 2242661 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28042 Saccharopolyspora rectivirgula Bacteria UP000031419 658525502, 658168505 KEI43204.1 WP_029719994.1 542 543 yes 2242662 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463902 Streptomyces sp. NRRL S-350 Bacteria 663195410 WP_030233299.1 601 604 yes 2242663 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 774, 1293911 Bartonella bacilliformis, Bartonella bacilliformis Ver097 Bacteria UP000059456, UP000031740 754289847, 657178671 KEG19962.1 WP_041849326.1 602 611 yes 2242664 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 662099293 WP_030055534.1 600 602 yes 2242665 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1459636 Candidatus Nitrososphaera evergladensis SR1 Archaea UP000028194 665994333 AIF84093.1 A0A075MSF5 A0A075MSF5_9ARCH 443 444 yes 2242666 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173509 Shewanella fidelis Bacteria 655362598 WP_028768779.1 655 665 yes 2242667 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463845 Streptomyces sp. NRRL F-2890 Bacteria 664198798 WP_030732464.1 528 532 yes 2242668 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1502784 Pseudomonas sp. AAC Bacteria UP000028226 759548732, 664811830 KES24755.1 WP_043268552.1 626 626 yes 2242669 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56450 Xanthomonas cassavae Bacteria 656274930 WP_029220586.1 623 625 yes 2242670 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 663359328 WP_030357810.1 590 593 yes 2242671 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 383381 Erythrobacter sp. JL475 Bacteria UP000027806 736958875, 660646488 KEO86333.1 WP_034955366.1 614 620 yes 2242672 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1318599 Dehalococcoidia bacterium SCGC AB-539-J10 Bacteria 657671906 WP_029474692.1 430 431 yes 2242673 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44575 Nitrosomonas cryotolerans Bacteria 655012433 WP_028461487.1 625 628 yes 2242674 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 658959235 WP_029808259.1 636 636 yes 2242675 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 232346 Halomonas alkaliantarctica Bacteria 662116126 WP_030070005.1 636 648 yes 2242676 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1927 Streptomyces rimosus Bacteria UP000028432 664060054 WP_030599086.1 589 593 yes 2242677 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444187 Escherichia coli, Escherichia coli 5-366-08_S3_C3 Bacteria UP000036210, UP000027621 727764913, 660075981 KEL71479.1 WP_033869511.1 626 631 yes 2242678 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 616992 gamma proteobacterium TG408 Bacteria 659836244 WP_029888525.1 624 629 yes 2242679 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463921 Streptomyces sp. NRRL S-920 Bacteria 664248647 WP_030780164.1 594 596 yes 2242680 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 971279, 1343739 Palaeococcus sp. DY20341, Palaeococcus pacificus DY20341 Archaea UP000027981 851300757, 664800344 AIF68577.1 WP_048164068.1 A0A075LRI6 A0A075LRI6_9EURY 425 425 yes 2242681 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 484770 Pelosinus sp. UFO1 Bacteria UP000027983 740884100, 664788189 AIF50862.1 WP_038669348.1 432 432 yes 2242682 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294 Pseudomonas fluorescens Bacteria UP000060991 657056413 WP_029299163.1 627 629 yes 2242683 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 94009 Thermicanus aegyptius Bacteria 655939638 WP_028987882.1 587 589 yes 2242684 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3880 Medicago truncatula Plants UP000002051 657393379 KEH34199.1 542 651 yes 2242685 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1130337 candidate division EM 19 bacterium JGI 0000106-P5 Bacteria 658438392 WP_029664713.1 190 191 no 2242686 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1130337 candidate division EM 19 bacterium JGI 0000106-P5 Bacteria 658438390 WP_029664712.1 278 278 no 2242687 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39645 Mesorhizobium ciceri Bacteria 657244871 WP_029356367.1 595 605 yes 2242688 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 743836 Methylocystis sp. SB2 Bacteria 658422291 WP_029648839.1 608 608 yes 2242689 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1137799 Endozoicomonas sp. HC50 Bacteria UP000028073 736840957, 662308640 KEQ13958.1 WP_034842070.1 573 575 yes 2242690 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 681847 Labrenzia sp. DG1229 Bacteria 656026141 WP_029065379.1 199 201 no 2242691 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1491, 1379740 Clostridium botulinum, Clostridium botulinum A2B2 87 Bacteria UP000030128, UP000027394 696532631, 658415182 KEJ02999.1 WP_033066111.1 437 437 yes 2242692 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463935 Streptomyces sp. NRRL WC-3744 Bacteria 664461026 WP_030982267.1 592 594 yes 2242693 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 103441 Pseudonocardia spinosispora Bacteria 655587196 WP_028934402.1 547 550 yes 2242694 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449077 Streptomyces sp. UNC401CLCol Bacteria 655859177 WP_028960871.1 595 598 yes 2242695 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851 Fusobacterium nucleatum Bacteria 657894049 WP_029597442.1 433 433 yes 2242696 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444145, 1444197 Escherichia coli, Escherichia coli 6-319-05_S3_C1, Escherichia coli 6-175-07_S3_C3 Bacteria UP000036210, UP000027919, UP000027889 693050501, 660124271, 660102727 KEM18655.1, KEL97668.1 WP_032219776.1 626 631 yes 2242697 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28131 Prevotella intermedia Bacteria UP000067008 655527420 WP_028905512.1 526 526 yes 2242698 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265 Ruminococcus flavefaciens Bacteria 655070231 WP_028518470.1 437 437 yes 2242699 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463852 Streptomyces sp. NRRL F-4835 Bacteria 664449688 WP_030971443.1 600 603 yes 2242700 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408310 Prevotella sp. MA2016 Bacteria 655549063 WP_028912232.1 527 528 yes 2242701 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 379535 Scytonema hofmanni UTEX 'B 1581' Bacteria 657932513 WP_029633718.1 456 457 yes 2242702 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44249, 1395586, 1395587 Paenibacillus sp. MAEPY1, Paenibacillus sp. MAEPY2 Bacteria UP000030062, UP000030061 659494424, 701619714, 701613424 KGP85442.1, KGP79270.1 WP_029881312.1 585 585 yes 2242703 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463851 Streptomyces sp. NRRL F-4474 Bacteria 664310296 WP_030839408.1 595 597 yes 2242704 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1488328 Pseudomonas sp. Ant30-3 Bacteria 655197227 WP_028621973.1 627 629 yes 2242705 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55952 Streptomyces toyocaensis Bacteria UP000028341 740086882, 664662683 KES05344.1 WP_037936241.1 599 602 yes 2242706 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463895 Streptomyces sp. NRRL S-237 Bacteria 664179872 WP_030713849.1 593 595 yes 2242707 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463925 Streptomyces sp. NRRL WC-3549 Bacteria 664565631 WP_031080187.1 292 293 yes 2242708 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1463925 Streptomyces sp. NRRL WC-3549 Bacteria 664565633 WP_031080189.1 311 323 no 2242709 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817 Bacteroides fragilis Bacteria UP000036847 695333165, 663460988, 663457664 KER56202.1, KER52920.1 WP_032530984.1 564 564 yes 2242710 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 133 133 no 2242711 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463843 Streptomyces sp. NRRL F-2747 Bacteria 664329549 WP_030857785.1 593 595 yes 2242712 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 938785 beta proteobacterium SCGC AAA027-K21 Bacteria 655417889 WP_028816480.1 636 637 yes 2242713 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40576, 1398204 Xenorhabdus bovienii, Xenorhabdus bovienii str. kraussei Becker Underwood Bacteria UP000032930, UP000028493 740356402, 666634725 WP_038192655.1 625 657 yes 2242714 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 286 655271789 WP_028681373.1 627 627 yes 2242715 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29432 Psychrobacter phenylpyruvicus Bacteria 655476870 WP_028859671.1 662 670 yes 2242716 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40576, 1398202 Xenorhabdus bovienii, Xenorhabdus bovienii str. oregonense Bacteria UP000032930, UP000028483 740419499, 666608990 WP_038252396.1 625 657 yes 2242717 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 314722 Pseudoxanthomonas suwonensis Bacteria UP000033067 655564929 WP_028918693.1 622 625 yes 2242718 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68223 Streptomyces katrae Bacteria UP000033551 663285627 WP_030292556.1 593 595 yes 2242719 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1506994 Butyrivibrio sp. AE3004 Bacteria 657206040 WP_029320445.1 434 434 yes 2242720 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 658962288 WP_029810043.1 640 646 yes 2242721 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53245 Desulfonatronovibrio hydrogenovorans Bacteria 655127772 WP_028574876.1 423 423 yes 2242722 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 616 635 yes 2242723 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 619 yes 2242724 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 574376 Bacillus sp. BL4-6 Bacteria UP000027822 736627216, 659907569 KEK21378.1 WP_034635212.1 586 586 yes 2242725 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56448, 454957 Xanthomonas arboricola, Xanthomonas arboricola pv. celebensis Bacteria UP000050499, UP000028245 746487906, 663490961 KER85192.1 WP_039525600.1 624 625 yes 2242726 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444212 Escherichia coli, Escherichia coli 5-366-08_S4_C1 Bacteria UP000036210, UP000028026 693230497, 660333473 KEO20931.1 WP_032343331.1 626 631 yes 2242727 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 231447 Desulfobulbus japonicus Bacteria 655133460 WP_028580504.1 442 442 yes 2242728 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456214 uncultured marine thaumarchaeote KM3_61_F08 Archaea 663523036 AIF13301.1 A0A075H9R9 A0A075H9R9_9ARCH 441 442 yes 2242729 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 517 518 yes 2242730 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43354 Prauserella rugosa Bacteria 663756790 WP_030532325.1 538 539 yes 2242731 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463881 Streptomyces sp. NRRL S-118 Bacteria 664557033 WP_031071847.1 593 595 yes 2242732 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456328 uncultured marine thaumarchaeote KM3_87_E01 Archaea 663529647 AIF19653.1 A0A075I0T9 A0A075I0T9_9ARCH 442 442 yes 2242733 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 671266 Enterorhabdus caecimuris Bacteria 665959031 WP_031324996.1 462 465 yes 2242734 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287182 Mesorhizobium sp. L48C026A00 Bacteria UP000019863 665888545 WP_031255751.1 559 571 yes 2242735 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 601 607 yes 2242736 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 104264, 1348584, 1495334 Cellulophaga baltica 18, Cellulophaga sp. E6(2014) Bacteria UP000030786, UP000029854 657641313, 730599198, 694992892 AIZ41993.1, KGK30682.1 WP_029445831.1 619 619 yes 2242737 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 574962, 1395571 Pseudomonas taeanensis, Pseudomonas taeanensis MS-3 Bacteria UP000030063 659055955, 680314632 KFX69666.1 WP_029866242.1 629 637 yes 2242738 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1288 Staphylococcus xylosus Bacteria UP000032432 755010104, 657169616 AID43854.1 WP_042363440.1 578 578 yes 2242739 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463904 Streptomyces sp. NRRL S-378 Bacteria 664432708 WP_030956847.1 593 595 yes 2242740 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66429 Streptomyces roseoverticillatus Bacteria 663368749 WP_030366795.1 585 586 yes 2242741 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1833 Rhodococcus erythropolis Bacteria UP000035201 665965838 WP_031331799.1 497 497 yes 2242742 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 664109900 WP_030647376.1 592 595 yes 2242743 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 88190 Thermus antranikianii Bacteria 655044171 WP_028492807.1 437 443 yes 2242744 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168697 Salinispora arenicola Bacteria 655265664 WP_028675835.1 530 530 yes 2242745 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40576, 1379677 Xenorhabdus bovienii, Xenorhabdus bovienii str. Intermedium Bacteria UP000032930, UP000028480 740348970, 666631657 WP_038185429.1 625 657 yes 2242746 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1908 Streptomyces globisporus Bacteria 664039892 WP_030579402.1 593 596 yes 2242747 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543632 Actinoplanes sp. RP-AC33 Bacteria 663629520 WP_030436536.1 505 508 yes 2242748 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 444919 Psychromonas aquimarina Bacteria 655481735 WP_028863564.1 642 660 yes 2242749 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1968 Streptomyces cellulosae Bacteria 664129255 WP_030666003.1 594 600 yes 2242750 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 619 yes 2242751 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 745718 Olleya sp. VCSM12 Bacteria 655161511 WP_028608062.1 619 619 yes 2242752 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1289387 Streptomyces sp. TAA204 Bacteria 654981004 WP_028430528.1 608 610 yes 2242753 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 80865, 80866, 1537702 Delftia acidovorans, Delftia sp. 670 Bacteria UP000029034, UP000028057 736342786, 673061649, 657327910 KFJ10346.1, KEH10128.1 WP_034368871.1 625 647 yes 2242754 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463871 Streptomyces sp. NRRL F-5727 Bacteria 664482823 WP_031003171.1 595 603 yes 2242755 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463864 Streptomyces sp. NRRL F-5630 Bacteria 664475432 WP_030996105.1 598 600 yes 2242756 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1178540 Bacillus sp. DW5-4 Bacteria UP000028091 736233692, 660775252 KEP26528.1 WP_034321294.1 586 586 yes 2242757 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78327 Pseudomonas mosselii Bacteria 655278873 WP_028688287.1 625 626 yes 2242758 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 663380794 WP_030376975.1 582 614 yes 2242759 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1384060 Rhodococcus sp. P27 Bacteria UP000016008 665967063 WP_031333024.1 497 497 yes 2242760 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173 Leptospira interrogans Bacteria UP000037872 658828945 WP_029781570.1 479 487 yes 2242761 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463840 Streptomyces sp. NRRL F-2305 Bacteria 664290553 WP_030820189.1 595 598 yes 2242762 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1282876 alpha proteobacterium Mf 1.05b.01 Bacteria 657937091 WP_029638191.1 601 618 yes 2242763 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1496688 Cyanobium sp. CACIA14 Bacteria UP000028237 737865988, 656718369 KEF41192.1 WP_035833002.1 457 462 yes 2242764 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 390877 Nisaea denitrificans Bacteria 655016359 WP_028465326.1 598 602 yes 2242765 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 658955045, 814970955 KKI07235.1 WP_029806211.1 640 647 yes 2242766 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66377 Streptomyces violens Bacteria 663222826 WP_030259606.1 591 594 yes 2242767 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 356302 Chitinimonas koreensis Bacteria 654996535 WP_028445775.1 638 639 yes 2242768 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487 Neisseria meningitidis Bacteria UP000050419 658462791 WP_029682831.1 625 635 yes 2242769 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456377 uncultured marine thaumarchaeote SAT1000_11_C10 Archaea 663533009 AIF22940.1 A0A075I524 A0A075I524_9ARCH 442 442 yes 2242770 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1491, 1443126 Clostridium botulinum, Clostridium botulinum C/D str. It1 Bacteria UP000030128, UP000027791 746182711, 658080790 KEH93763.1 WP_039241876.1 437 437 yes 2242771 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 219182 Ottowia thiooxydans Bacteria 655158038 WP_028604681.1 624 628 yes 2242772 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 664102563 WP_030640075.1 592 594 yes 2242773 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 306543 Paenibacillus harenae Bacteria 655163390 WP_028609914.1 586 587 yes 2242774 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 262077 Marinobacter daepoensis Bacteria 658428919 WP_029655270.1 622 625 yes 2242775 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3750 Malus x domestica Plants 657951972 XP_008355280.1 542 652 yes 2242776 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 452529 Streptomyces sp. RB72 Bacteria 663351089 WP_030349864.1 605 608 yes 2242777 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40576, 1398203 Xenorhabdus bovienii, Xenorhabdus bovienii str. kraussei Quebec Bacteria UP000032930, UP000028500 740409926, 666612736 WP_038243387.1 625 657 yes 2242778 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686273621, 655808055 KEE86614.1 WP_031852714.1 640 646 yes 2242779 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463841 Streptomyces sp. NRRL F-2580 Bacteria 664173766 WP_030707768.1 593 595 yes 2242780 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 371720 Streptomyces monomycini Bacteria 662056782 WP_030022917.1 593 596 yes 2242781 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1274 Dermacoccus nishinomiyaensis Bacteria UP000027986 740785611, 664688206 AIF40796.1 WP_038570895.1 599 621 yes 2242782 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 64973 Terasakiella pusilla Bacteria 655498259 WP_028879588.1 593 596 yes 2242783 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 340095 Thermodesulfovibrio thiophilus Bacteria 655462582 WP_028845545.1 426 426 yes 2242784 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 311244 Paenibacillus assamensis Bacteria 655147945 WP_028594699.1 600 609 yes 2242785 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444189 Escherichia coli, Escherichia coli 8-415-05_S3_C3 Bacteria UP000036210, UP000028029 693156615, 660239618 KEN30739.1 WP_032292908.1 626 631 yes 2242786 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463824 Nocardia sp. NRRL WC-3656 Bacteria 663740617 WP_030516597.1 542 543 yes 2242787 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1117244 Xanthobacter sp. 91 Bacteria 657842927 WP_029558022.1 612 624 yes 2242788 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67275 Streptomyces aureocirculatus Bacteria 664007762 WP_030559746.1 593 595 yes 2242789 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 57480 Microvirgula aerodenitrificans Bacteria 655049350 WP_028497933.1 635 636 yes 2242790 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 698769 Virgibacillus sp. J18 Bacteria 657024400 WP_029268163.1 594 594 yes 2242791 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 240 240 no 2242792 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1912 Streptomyces hygroscopicus Bacteria 664298185 WP_030827628.1 586 587 yes 2242793 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 172088 Bradyrhizobium sp. th.b2 Bacteria 656040279 WP_029078983.1 622 632 yes 2242794 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1435425 Pseudomonas sp. QTF5 Bacteria 662763753 WP_030130464.1 628 629 yes 2242795 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67298 Streptomyces flavidovirens Bacteria 655415899 WP_028814681.1 590 591 yes 2242796 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463934 Streptomyces sp. NRRL WC-3742 Bacteria 664562238 WP_031076996.1 602 608 yes 2242797 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 658981159 WP_029823302.1 640 646 yes 2242798 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265 Ruminococcus flavefaciens Bacteria 655066506 WP_028514791.1 437 437 yes 2242799 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 934 Thiomicrospira pelophila Bacteria 659886666 WP_029933351.1 619 629 yes 2242800 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34011 Azospirillum irakense Bacteria 655971127 WP_029013714.1 608 620 yes 2242801 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1428 Bacillus thuringiensis Bacteria UP000031834 657633019 WP_029443625.1 586 586 yes 2242802 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168697 Salinispora arenicola Bacteria 655265792 WP_028675959.1 530 530 yes 2242803 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463937 Streptomyces sp. NRRL WC-3774 Bacteria 664523410 WP_031039955.1 593 596 yes 2242804 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37925 Thermocrispum agreste Bacteria 655465702 WP_028848648.1 540 556 yes 2242805 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 525917 Thiothrix lacustris Bacteria 655041569 WP_028490277.1 616 620 yes 2242806 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1896 Streptomyces bikiniensis Bacteria 663167900 WP_030206866.1 588 596 yes 2242807 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82987, 1005995 Tatumella ptyseos, Tatumella ptyseos ATCC 33301 Bacteria UP000028602 661297884, 669011339 KFD22436.1 WP_029990745.1 630 641 yes 2242808 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1583098 Fusobacterium hwasookii Bacteria 657693946 WP_029493587.1 433 433 yes 2242809 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1385935 Leptolyngbya sp. Heron Island J Bacteria UP000017515 665927361 WP_031293412.1 455 457 yes 2242810 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 50340 Pseudomonas fuscovaginae Bacteria UP000037883 657782312 WP_029532944.1 633 635 yes 2242811 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 76594 Cellulophaga baltica Bacteria 657644049 WP_029448530.1 619 619 yes 2242812 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40576, 1397852, 1397851 Xenorhabdus bovienii, Xenorhabdus bovienii str. feltiae Florida, Xenorhabdus bovienii str. feltiae France Bacteria UP000032930, UP000028506, UP000028509 740366001, 666622007, 666618225 WP_038201518.1 625 657 yes 2242813 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463836 Streptomyces sp. NRRL B-3229 Bacteria 663319613 WP_030319481.1 601 615 yes 2242814 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2426 Teredinibacter turnerae Bacteria 655494186 WP_028875584.1 638 639 yes 2242815 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1137268 Nocardiopsis sp. CNT312 Bacteria 655237138 WP_028648480.1 548 558 yes 2242816 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1476877 Streptomyces sp. NRRL B-1347 Bacteria 664140418 WP_030676988.1 593 603 yes 2242817 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449087 Thiomicrospira sp. MA2-6 Bacteria 659892742 WP_029939417.1 621 629 yes 2242818 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1130318 euryarchaeote SCGC AAA261-G15 Archaea 656263407 WP_029209361.1 91 92 no 2242819 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444047 Escherichia coli, Escherichia coli 5-366-08_S1_C1 Bacteria UP000036210, UP000027710 693235611, 660069544 KEL65261.1 WP_032346476.1 626 631 yes 2242820 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380355 Bradyrhizobium sp. URHD0069 Bacteria 657882998 WP_029587348.1 622 632 yes 2242821 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1472716 Burkholderia sp. K24 Bacteria 662153807, 680269096 KFX64115.1 WP_030101627.1 642 643 yes 2242822 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204039 Dickeya dianthicola Bacteria 658535263 WP_029729200.1 631 655 yes 2242823 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47761 Streptomyces ochraceiscleroticus Bacteria 664533748 WP_031049866.1 590 592 yes 2242824 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686142306, 655702013 KED93295.1 WP_031778516.1 640 646 yes 2242825 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 757504680, 655677752 KED71589.1 WP_042772980.1 640 646 yes 2242826 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1892 Streptomyces anulatus Bacteria UP000050620 664034939 WP_030576072.1 583 611 yes 2242827 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686272513, 655675532 KED69719.1 WP_031851817.1 640 646 yes 2242828 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1160, 388467 Planktothrix agardhii, Planktothrix agardhii NIVA-CYA 126/8 Bacteria UP000027395 754791891, 658299769 KEI68164.1 WP_042155483.1 458 459 yes 2242829 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463908 Streptomyces sp. NRRL S-455 Bacteria 663199667 WP_030237527.1 599 600 yes 2242830 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 655642687 KED41150.1 640 646 yes 2242831 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1353532 Thalassospira permensis NBRC 106175 Bacteria UP000027463 660525889 KEO55728.1 606 648 yes 2242832 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 52258 Streptomyces flavovirens Bacteria 664096631 WP_030634512.1 589 609 yes 2242833 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 601 610 yes 2242834 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444100 Escherichia coli, Escherichia coli 2-460-02_S1_C3 Bacteria UP000036210, UP000027747 693005624, 658694335 KEJ37173.1 WP_032190339.1 626 631 yes 2242835 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1433126 Rikenellaceae bacterium M3 Bacteria UP000027616 656328474 497 497 yes 2242836 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471437 Prochlorococcus sp. scB241_526B17 Bacteria 661256507 WP_029951771.1 136 137 no 2242837 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444163 Escherichia coli, Escherichia coli 1-250-04_S3_C2 Bacteria UP000036210, UP000027995 693140211, 660341523 KEO28694.1 WP_032281691.1 626 631 yes 2242838 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59839 Paenibacillus alginolyticus Bacteria 656251853 WP_029198372.1 594 594 yes 2242839 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1270196 Pedobacter sp. R20-19 Bacteria 657043095 WP_029286163.1 627 627 yes 2242840 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3750 Malus x domestica Plants 657985493, 657985491, 657985489 XP_008384843.1, XP_008384842.1, XP_008384841.1 550 648 yes 2242841 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380384 Tenacibaculum sp. 47A_GOM-205m Bacteria 655509686 WP_028890760.1 619 619 yes 2242842 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1583098 Fusobacterium hwasookii Bacteria 657691605 WP_029491420.1 433 433 yes 2242843 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1476876 Streptomyces sp. NRRL B-24720 Bacteria 664404741 WP_030930612.1 593 602 yes 2242844 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 758826 Acidovorax sp. N35 Bacteria 657602602 WP_029413938.1 622 626 yes 2242845 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53427 Gordonia hirsuta Bacteria 658621525 WP_029759729.1 508 508 yes 2242846 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 231447 Desulfobulbus japonicus Bacteria 655132074 WP_028579130.1 430 430 yes 2242847 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1827 656323724 WP_029254782.1 497 497 yes 2242848 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68194 Streptomyces durhamensis Bacteria 665592957 WP_031164420.1 592 594 yes 2242849 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 657866513 WP_029572073.1 627 629 yes 2242850 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463829 Streptomyces sp. NRRL B-1381 Bacteria 663329760 WP_030329291.1 593 595 yes 2242851 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 328301 Syntrophorhabdus aromaticivorans Bacteria 655512854 WP_028893917.1 426 426 yes 2242852 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29306 Streptomyces griseoluteus Bacteria 663165909 WP_030204893.1 593 595 yes 2242853 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456233 uncultured marine thaumarchaeote KM3_67_B10 Archaea 663524154 AIF14388.1 A0A075HKA4 A0A075HKA4_9ARCH 442 442 yes 2242854 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 711393 Streptomyces sp. GXT6 Bacteria 654971593 WP_028421293.1 593 601 yes 2242855 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1957 Streptomyces sclerotialus Bacteria 664076822 WP_030615375.1 594 597 yes 2242856 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471438 Prochlorococcus sp. scB241_526B19 Bacteria 661264820 WP_029959569.1 90 90 no 2242857 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463888 Streptomyces sp. NRRL S-1813 Bacteria 664469494 WP_030990675.1 587 594 yes 2242858 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1453492 Chryseobacterium hispalense Bacteria 657053594 WP_029296384.1 603 603 yes 2242859 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487 Neisseria meningitidis Bacteria UP000050419 658459963 WP_029682425.1 619 627 yes 2242860 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1046935 candidate division BRC1 bacterium SCGC AAA257-C11 Bacteria 658516575 WP_029711878.1 435 435 yes 2242861 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1927 Streptomyces rimosus Bacteria UP000028432 664110991 WP_030648460.1 590 593 yes 2242862 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1185766 Thioclava sp. DLFJ1-1 Bacteria UP000027725 740220117, 661437613 KEP71334.1 WP_038061895.1 591 598 yes 2242863 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 600 610 yes 2242864 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 153721 Sporocytophaga myxococcoides Bacteria UP000030185 655909583 WP_028979826.1 619 619 yes 2242865 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 230667 Chitinibacter tainanensis Bacteria 654999490 WP_028448687.1 637 638 yes 2242866 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1303256 Sphingobium sp. DC-2 Bacteria 663818231 WP_030539232.1 611 615 yes 2242867 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380389 Sphingomonas sp. URHD0057 Bacteria 655885098 WP_028968617.1 643 645 yes 2242868 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1172179 Streptomyces sp. 142MFCol3.1 Bacteria 655405183 WP_028804061.1 596 606 yes 2242869 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1957 Streptomyces sclerotialus Bacteria 664034970 WP_030576093.1 596 608 yes 2242870 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392486 Prevotella sp. HUN102 Bacteria 655515894 WP_028896950.1 528 528 yes 2242871 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 217090 Paenibacillus pasadenensis Bacteria 655151413 WP_028598132.1 585 586 yes 2242872 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1048983 Cytophagaceae bacterium ANESC-S Bacteria UP000027821 737090999, 660629977 KEO71755.1 WP_035079393.1 618 619 yes 2242873 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 659048735 WP_029862240.1 640 646 yes 2242874 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 356851 Micromonospora chokoriensis Bacteria 663712922 WP_030489615.1 530 530 yes 2242875 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392491 Ruminococcaceae bacterium AE2021 Bacteria 655063292 WP_028511583.1 434 435 yes 2242876 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1044 Erythrobacter longus Bacteria UP000027647 736962098, 660652471 KEO92189.1 WP_034958583.1 626 629 yes 2242877 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 394734 Nocardioides insulae Bacteria 655250342 WP_028661024.1 549 551 yes 2242878 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470 470 yes 2242879 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 537 541 yes 2242880 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 523 Acidiphilium angustum Bacteria 657198056 WP_029313718.1 603 606 yes 2242881 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 160808 Acidithiobacillus ferrivorans Bacteria UP000029069 737206843, 669955989 WP_035191672.1 626 627 yes 2242882 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1370121 Mycobacterium sp. UM_WWY Bacteria 657266298 WP_029370066.1 535 538 yes 2242883 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29450 Rhizobium tropici IIA Bacteria 655346829 WP_028754519.1 600 608 yes 2242884 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 551276 Pseudonocardia acaciae Bacteria 655570782 WP_028924468.1 547 550 yes 2242885 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463842 Streptomyces sp. NRRL F-2664 Bacteria 664229975 WP_030762597.1 593 595 yes 2242886 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53412 Pseudomonas resinovorans Bacteria 655210382 WP_028630623.1 627 627 yes 2242887 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1121276 Chitinilyticum litopenaei Bacteria 655005562 WP_028454715.1 637 638 yes 2242888 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456298 uncultured marine thaumarchaeote KM3_79_H05 Archaea 663527838 AIF17975.1 A0A075HR99 A0A075HR99_9ARCH 442 442 yes 2242889 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1169152 Nocardia sp. CNY236 Bacteria 655030586 WP_028479414.1 536 538 yes 2242890 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 663248083 WP_030278196.1 602 604 yes 2242891 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463917 Streptomyces sp. NRRL S-646 Bacteria 664413148 WP_030938807.1 595 600 yes 2242892 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 74311 Brevundimonas bacteroides Bacteria 657603698 WP_029414951.1 623 624 yes 2242893 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1313265 Thermocrinis sp. GBS Bacteria 657835403 WP_029551408.1 453 455 yes 2242894 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285535 Streptomyces fulvoviolaceus Bacteria 664070423 WP_030609018.1 594 601 yes 2242895 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 661308214 WP_030000381.1 640 646 yes 2242896 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40576, 1398200 Xenorhabdus bovienii, Xenorhabdus bovienii str. feltiae Moldova Bacteria UP000032930, UP000028487 740386995, 303022440, 167320626, 666623962 ADL76788.1, ABZ57219.1 WP_038221359.1 625 657 yes 2242897 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1421 Lysinibacillus sphaericus Bacteria UP000028424 738265506, 659843898 KEK13407.1 WP_036220246.1 592 592 yes 2242898 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47880 Pseudomonas fulva Bacteria UP000032068 655278472 WP_028687911.1 625 626 yes 2242899 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 211114 Kibdelosporangium albatum Bacteria 663598066 WP_030432823.1 546 548 yes 2242900 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1914 Streptomyces lavendulae Bacteria 663187129 WP_030225272.1 593 595 yes 2242901 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463903 Streptomyces sp. NRRL S-37 Bacteria 664328904 WP_030857142.1 595 598 yes 2242902 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463889 Streptomyces sp. NRRL S-1824 Bacteria 664452076 WP_030973817.1 589 591 yes 2242903 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 619 yes 2242904 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 645 650 yes 2242905 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375288, 1203610, 1078087 Parabacteroides gordonii MS-1, Parabacteroides sp. HGS0025 Bacteria UP000033035, UP000033081 655320954, 805430905, 805430220 KKB50591.1, KKB51568.1 WP_028729346.1 568 568 yes 2242906 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686146427, 655632387 KED31942.1 WP_031781569.1 425 431 yes 2242907 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1504156 Microbacterium sp. SUBG002 Bacteria UP000032117 661515053 KEP71976.1 125 125 no 2242908 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444046 Escherichia coli, Escherichia coli 5-172-05_S1_C1 Bacteria UP000036210, UP000027664 696362137, 660084875 KEL80152.1 WP_032937284.1 626 632 yes 2242909 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 400061 Paludibacterium yongneupense Bacteria 655087062 WP_028535060.1 632 632 yes 2242910 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1397532 Marinobacter sp. EVN1 Bacteria UP000017112 665841378 WP_031209495.1 622 625 yes 2242911 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463832 Streptomyces sp. NRRL B-24051 Bacteria 664348776 WP_030876449.1 586 612 yes 2242912 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158345 Persephonella sp. KM09-Lau-8 Bacteria 657725540 WP_029522114.1 452 452 yes 2242913 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449064 Paenibacillus sp. UNCCL52 Bacteria 655093173 WP_028541006.1 593 614 yes 2242914 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935866 Nocardioides sp. J54 Bacteria 655243312 WP_028654576.1 552 556 yes 2242915 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 659019920, 726135664 KHF06882.1 WP_029847850.1 640 646 yes 2242916 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 817 Bacteroides fragilis Bacteria UP000036847 695347491, 663465081 KER59941.1 WP_032544036.1 564 564 yes 2242917 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 364039 Azohydromonas australica Bacteria 655954418 WP_028997313.1 612 621 yes 2242918 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851 Fusobacterium nucleatum Bacteria 658615631 WP_029758440.1 433 433 yes 2242919 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 658979087 WP_029821750.1 456 478 yes 2242920 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 619 yes 2242921 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1288 Staphylococcus xylosus Bacteria UP000032432 657291355 WP_029378803.1 578 578 yes 2242922 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 417574 Neptunomonas japonica Bacteria 655021707 WP_028470641.1 625 625 yes 2242923 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1464048 Micromonospora parva Bacteria 663330427 WP_030329954.1 530 530 yes 2242924 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 594 598 yes 2242925 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 486 Neisseria lactamica Bacteria 657906725 WP_029609348.1 625 633 yes 2242926 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 659051888 WP_029863462.1 396 396 no 2242927 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463857 Streptomyces sp. NRRL F-5126 Bacteria 664378646 WP_030905311.1 587 588 yes 2242928 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 571, 1333852 Klebsiella oxytoca, Klebsiella oxytoca KONIH1 Bacteria UP000030350, UP000027428 695807034, 834124016, 834121312, 721577607, 668899601, 662707819, 660567853 KLU50994.1, KLU48343.1, KGZ20906.1, KFC33343.1, AIE68128.1, AID87773.1 WP_032721073.1 626 631 yes 2242929 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 877411 rumen bacterium NK3A76 Bacteria 655062185 WP_028510478.1 433 434 yes 2242930 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 424 424 yes 2242931 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1270193 Flavobacterium sp. KJJ Bacteria 657028317 WP_029271939.1 607 607 yes 2242932 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 436229 Streptacidiphilus jeojiense Bacteria 663217966 WP_030254798.1 610 614 yes 2242933 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66849 Desulfonatronum lacustre Bacteria 655125983 WP_028573098.1 433 434 yes 2242934 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1744, 66712 Propionibacterium freudenreichii, Propionibacterium freudenreichii subsp. freudenreichii Bacteria UP000049199, UP000028865 739069125, 808438344, 808427704, 732163606, 659918371 WP_036940508.1 621 630 yes 2242935 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1282361 Asticcacaulis sp. AC402 Bacteria UP000017812 665867956 WP_031235163.1 610 613 yes 2242936 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456227 uncultured marine thaumarchaeote KM3_66_A07 Archaea 663523890 AIF14132.1 A0A075HI51 A0A075HI51_9ARCH 442 442 yes 2242937 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 303 Pseudomonas putida Bacteria UP000054813 659679261 WP_029887207.1 625 626 yes 2242938 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294 Pseudomonas fluorescens Bacteria UP000060991 662778810 WP_030140188.1 628 629 yes 2242939 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 662125636 WP_030077314.1 593 596 yes 2242940 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 927677 Synechocystis sp. PCC 7509 Bacteria 497318563 WP_009632776.1 454 456 yes 2242941 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1094943 Sphingomonas sp. JGI 0001002-I20 Bacteria 658531272 WP_029725522.1 537 541 no 2242942 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 839 Prevotella ruminicola Bacteria 655533771 WP_028907945.1 527 528 yes 2242943 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1764 Mycobacterium avium Bacteria 665986813 WP_031351850.1 465 467 yes 2242944 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410617 Ruminococcus sp. FC2018 Bacteria 655057772 WP_028506141.1 433 434 yes 2242945 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 401638 Paenibacillus taiwanensis Bacteria 655096861 WP_028544646.1 584 585 yes 2242946 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463898 Streptomyces sp. NRRL S-31 Bacteria 664202472 WP_030735972.1 592 594 yes 2242947 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463900 Streptomyces sp. NRRL S-337 Bacteria 664267450 WP_030798287.1 589 596 yes 2242948 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1455955 uncultured marine thaumarchaeote KM3_02_A10 Archaea 663506958 AIE97677.1 A0A075G7F5 A0A075G7F5_9ARCH 442 442 yes 2242949 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1354304 Xenorhabdus poinarii G6 Bacteria UP000032735 661566387 625 659 yes 2242950 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 171121 Sulfurihydrogenibium subterraneum Bacteria 655818721 WP_028950599.1 448 452 yes 2242951 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456358 uncultured marine thaumarchaeote SAT1000_05_G10 Archaea 663531687 AIF21642.1 A0A075I4D2 A0A075I4D2_9ARCH 442 442 yes 2242952 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463868 Streptomyces sp. NRRL F-5650 Bacteria 664523553 WP_031040097.1 596 607 yes 2242953 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 659051388 WP_029863339.1 258 264 no 2242954 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 442 481 yes 2242955 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 157783 Pseudomonas cremoricolorata Bacteria UP000029493 655285639 WP_028694992.1 627 628 yes 2242956 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444063 Escherichia coli, Escherichia coli 6-537-08_S1_C1 Bacteria UP000036210, UP000027803 693057759, 660143042 KEM37013.1 WP_032225454.1 626 631 yes 2242957 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1914 Streptomyces lavendulae Bacteria 662043840 WP_030011722.1 593 595 yes 2242958 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423 Bacillus subtilis Bacteria UP000030083 657203072 WP_029317515.1 590 590 yes 2242959 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471489, 408172 Prochlorococcus sp. scB243_498B23, marine metagenome Bacteria, Environmental samples 661292347, 140139457 ECJ80163.1 WP_029985423.1 184 185 no 2242960 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1458427 Comamonadaceae bacterium H1 Bacteria 657657581 WP_029461528.1 636 643 yes 2242961 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851 Fusobacterium nucleatum Bacteria 657897198 WP_029600291.1 376 376 yes 2242962 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 866564 Polaromonas sp. Cr4-12 Bacteria 657730287 WP_029526838.1 638 638 yes 2242963 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 104270 Tenacibaculum ovolyticum Bacteria 655506333 WP_028887443.1 619 619 yes 2242964 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1496690 Rhizobium sp. MGL06 Bacteria 657917933 WP_029619776.1 600 606 yes 2242965 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 619 yes 2242966 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 561879 Bacillus safensis Bacteria UP000032451 736614064, 660807753 KEP30704.1 WP_034622399.1 586 586 yes 2242967 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456340 uncultured marine thaumarchaeote KM3_89_G03 Archaea 663530433 AIF20419.1 A0A075HXQ5 A0A075HXQ5_9ARCH 442 442 yes 2242968 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463854 Streptomyces sp. NRRL F-5053 Bacteria 664358405 WP_030885931.1 598 599 yes 2242969 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 81406 Desulfovibrio alcoholovorans Bacteria 657656355 WP_029460780.1 417 436 no 2242970 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1961 Streptomyces virginiae Bacteria UP000037084 664366823 WP_030893958.1 592 595 yes 2242971 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463932 Streptomyces sp. NRRL WC-3719 Bacteria 665526100 WP_031128013.1 589 591 yes 2242972 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463892 Streptomyces sp. NRRL S-1868 Bacteria 664353186 WP_030880828.1 598 599 yes 2242973 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463863 Streptomyces sp. NRRL F-5555 Bacteria 663407479 WP_030403105.1 592 607 yes 2242974 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1094944 Sphingomonas sp. JGI 0001003-D23 Bacteria 658530469 WP_029724749.1 620 631 yes 2242975 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55601 Listonella anguillarum Bacteria UP000030318 656243306 WP_029189936.1 640 649 yes 2242976 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1908 Streptomyces globisporus Bacteria 664149901 WP_030685690.1 592 594 yes 2242977 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463926 Streptomyces sp. NRRL WC-3626 Bacteria 663176927 WP_030215527.1 594 597 yes 2242978 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1455981 uncultured marine thaumarchaeote KM3_105_E03 Archaea 663508391 AIE99070.1 A0A075G4X7 A0A075G4X7_9ARCH 442 442 yes 2242979 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 549 Pantoea agglomerans Bacteria UP000050560 727317880, 666371330 KEY41539.1 WP_033773295.1 632 640 yes 2242980 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 438033 Ruminococcus gauvreauii Bacteria 655081751 WP_028529838.1 434 434 yes 2242981 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3880 Medicago truncatula Plants UP000002051 657393381 KEH34201.1 549 648 yes 2242982 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386078 Pseudomonas sp. EGD-AK9 Bacteria UP000016488 665936514 WP_031302564.1 627 627 yes 2242983 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294 Pseudomonas fluorescens Bacteria UP000060991 740660254, 666088534 AIG04454.1 WP_038445553.1 627 629 yes 2242984 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 1609137 Streptomyces sp. NRRL F-4428 Bacteria UP000033569 662059761, 770218569 KJK54605.1 WP_030025785.1 592 595 yes 2242985 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 759401209, 663469909 KER64736.1 WP_043125709.1 645 663 yes 2242986 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1888 Streptomyces albus Bacteria 663976497 WP_030543714.1 586 591 yes 2242987 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 551 553 yes 2242988 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 399548 Desulfocurvus vexinensis Bacteria 655140792 WP_028587648.1 416 423 yes 2242989 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46429 Sphingobium chlorophenolicum Bacteria UP000028411 739590857, 662356152 KEQ54573.1 WP_037448458.1 614 622 yes 2242990 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 157782 Pseudomonas parafulva Bacteria UP000030632 655212435 WP_028631863.1 625 626 yes 2242991 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1147 Synechocystis sp. PCC 6714 Bacteria UP000027989 655741332, 662703511 AIE73486.1 WP_028948982.1 457 459 yes 2242992 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423, 1290773 Bacillus subtilis, Bacillus subtilis E1 Bacteria UP000030083, UP000027587 695811370, 659925574 WP_032725256.1 590 590 yes 2242993 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68242, 1240678 Streptomyces natalensis, Streptomyces natalensis ATCC 27448 Bacteria UP000032458 662108983, 762057582 KIZ19336.1 WP_030064498.1 596 602 yes 2242994 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67373 Streptomyces varsoviensis Bacteria UP000037020 664354680 WP_030882303.1 588 608 yes 2242995 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54736, 1382510 Salmonella bongori, Salmonella bongori serovar 48:z41:-- str. RKS3044 Bacteria UP000027125 740607941, 657149506 AID26603.1 WP_038393473.1 626 631 yes 2242996 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 435 435 yes 2242997 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456420 uncultured marine thaumarchaeote SAT1000_52_D06 Archaea 663535706 AIF25562.1 A0A075IF33 A0A075IF33_9ARCH 442 442 yes 2242998 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 362520 Chitinilyticum aquatile Bacteria 655003691 WP_028452869.1 637 638 yes 2242999 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56448, 454957 Xanthomonas arboricola, Xanthomonas arboricola pv. celebensis Bacteria UP000050499, UP000028245 746481320, 663493311 KER87459.1 WP_039519122.1 624 625 yes 2243000 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 3750 Malus x domestica Plants 658046836 XP_008359081.1 387 473 no 2243001 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463884 Streptomyces sp. NRRL S-146 Bacteria 664595542 WP_031107542.1 592 594 yes 2243002 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463936 Streptomyces sp. NRRL WC-3773 Bacteria 664486376 WP_031006689.1 590 592 yes 2243003 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1385 661279591 WP_029973241.1 590 590 yes 2243004 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686144700, 655708206 KED98900.1 WP_031780081.1 313 313 yes 2243005 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65497 Actinoalloteichus cyanogriseus Bacteria 662157392 WP_030105145.1 543 554 yes 2243006 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543 544 yes 2243007 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 54010 Pseudonocardia asaccharolytica Bacteria 655578304 WP_028929616.1 544 546 yes 2243008 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 284040 Streptomyces variegatus Bacteria UP000034786 665544936, 770201665 KJK40156.1 WP_031137706.1 598 600 yes 2243009 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1454, 1348973 Bacillus azotoformans, Bacillus azotoformans MEV2011 Bacteria UP000027936 737214356, 656679086 KEF35879.1 WP_035199074.1 594 594 yes 2243010 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 664499189 WP_031018177.1 595 598 yes 2243011 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158338 Persephonella sp. IF05-L8 Bacteria 657724893 WP_029521469.1 452 452 yes 2243012 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305 Ralstonia solanacearum Bacteria UP000029286 655478054 WP_028860055.1 629 631 yes 2243013 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 411 411 no 2243014 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463844 Streptomyces sp. NRRL F-2799 Bacteria 664275954 WP_030806144.1 595 601 yes 2243015 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 24 Shewanella putrefaciens Bacteria 655353363 WP_028759839.1 655 706 yes 2243016 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1548 Clostridium scatologenes Bacteria UP000033115 656212146, 800897670 AKA69854.1 WP_029161553.1 437 437 yes 2243017 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 851 Fusobacterium nucleatum Bacteria 657893904 WP_029597331.1 433 433 yes 2243018 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444087 Escherichia coli, Escherichia coli 3-475-03_S1_C2 Bacteria UP000036210, UP000027625 693079391, 659977671 KEK77290.1 WP_032241736.1 626 631 yes 2243019 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 436 438 yes 2243020 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 407188 Pelobacter seleniigenes Bacteria 659870536 WP_029917399.1 432 432 yes 2243021 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686265198, 655817198 KEE93902.1 WP_031846223.1 640 646 yes 2243022 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456175 uncultured marine thaumarchaeote KM3_51_F10 Archaea 663521082 AIF11400.1 A0A075H8K7 A0A075H8K7_9ARCH 445 446 yes 2243023 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463858 Streptomyces sp. NRRL F-5135 Bacteria 664211312 WP_030744535.1 619 624 yes 2243024 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 619 yes 2243025 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 664371195 WP_030898157.1 593 594 yes 2243026 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1079800 Rhizobium sp. CCGE 503 Bacteria 655338332 WP_028746444.1 599 608 yes 2243027 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168697 Salinispora arenicola Bacteria 655985100 WP_029026919.1 530 530 yes 2243028 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 168695 Salinispora tropica Bacteria 655121468 WP_028568793.1 537 537 yes 2243029 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 574560, 1393735 Photorhabdus temperata, Photorhabdus temperata subsp. temperata Meg1 Bacteria UP000028002 738955700, 662547865 KER02369.1 WP_036840125.1 619 642 yes 2243030 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 663377943 WP_030374289.1 590 593 yes 2243031 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84590 Taylorella asinigenitalis Bacteria 655502629 WP_028883877.1 622 624 yes 2243032 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 929 Thermithiobacillus tepidarius Bacteria 655941437 WP_028989653.1 631 632 yes 2243033 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66883 Streptomyces cyaneofuscatus Bacteria 664013994 WP_030562998.1 593 596 yes 2243034 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1996 Microtetraspora glauca Bacteria 663717171 WP_030493807.1 590 591 yes 2243035 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3656 Cucumis melo Plants 659115103, 659115101, 659115099 XP_008457388.1, XP_008457387.1, XP_008457386.1 552 647 yes 2243036 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463883 Streptomyces sp. NRRL S-1448 Bacteria 663416696 WP_030411989.1 589 596 yes 2243037 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1495066 Pseudomonas sp. WCS358 Bacteria UP000028386 727241887, 666445775 KEY85916.1 WP_033701840.1 625 626 yes 2243038 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 316 Pseudomonas stutzeri Bacteria UP000037382 657347789 WP_029404616.1 626 626 yes 2243039 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 418702 beta proteobacterium d8-1 Bacteria 655950720 WP_028993660.1 637 638 yes 2243040 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1571 Sporosarcina ureae Bacteria 656013945 WP_029053888.1 590 590 yes 2243041 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 418856 Nevskia soli Bacteria 659874846 WP_029921679.1 634 637 yes 2243042 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 63656 Thiomicrospira chilensis Bacteria 655038419 WP_028487176.1 641 645 yes 2243043 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298864 Mycobacterium sp. URHD0025 Bacteria 656079722 WP_029110777.1 539 543 yes 2243044 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463853 Streptomyces sp. NRRL F-5008 Bacteria 664263564 WP_030794917.1 590 602 yes 2243045 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40571 Lentzea albidocapillata Bacteria 663703749 WP_030480605.1 539 546 yes 2243046 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 605 619 yes 2243047 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456123 uncultured marine thaumarchaeote KM3_32_D07 Archaea 663518383 AIF08776.1 A0A075GY00 A0A075GY00_9ARCH 439 439 yes 2243048 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 648 Aeromonas punctata Bacteria UP000054115 752540783, 662018044 KEP90793.1 WP_041212230.1 649 667 yes 2243049 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1911 Streptomyces griseus Bacteria UP000032367 664173367 WP_030707371.1 593 596 yes 2243050 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1927 Streptomyces rimosus Bacteria UP000028432 664128648 WP_030665410.1 591 593 yes 2243051 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1298880 Streptomyces sp. TAA486 Bacteria 654988957 WP_028438409.1 613 615 yes 2243052 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1147787 Pseudomonas aeruginosa, Pseudomonas aeruginosa PAO1H2O Bacteria UP000065817, UP000027421 740618527, 660509570 AID76179.1 WP_038404041.1 627 627 yes 2243053 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1506588 Burkholderia sp. MSh2 Bacteria UP000028429 736054314, 666487703 KEZ05689.1 WP_034197855.1 642 643 yes 2243054 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410614 Prevotella sp. P6B4 Bacteria 655522938 WP_028903614.1 528 528 yes 2243055 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 664222646 WP_030755460.1 593 595 yes 2243056 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1353528 Thioclava sp. DT23-4 Bacteria UP000027471 740295341, 660521429 KEO51389.1 WP_038133560.1 591 594 yes 2243057 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 399, 323655, 1028800 Rhizobium galegae, Rhizobium galegae bv. orientalis, Rhizobium galegae bv. orientalis str. HAMBI 540 Bacteria UP000041927, UP000028181 740806054, 816167453, 659657037 WP_038591337.1 600 603 yes 2243058 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 49390 Coffea canephora Plants 661887383 546 647 yes 2243059 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392494 Lachnospiraceae bacterium AC2012 Bacteria 657707560 WP_029506217.1 434 435 yes 2243060 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 388051 Cupriavidus sp. amp6 Bacteria 656005920 WP_029047354.1 624 626 yes 2243061 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471468 Prochlorococcus sp. scB241_529O19 Bacteria 661286765 WP_029979853.1 96 96 no 2243062 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444227 Escherichia coli, Escherichia coli 6-537-08_S4_C1 Bacteria UP000036210, UP000027645 693060827, 660196740 KEM88973.1 WP_032227806.1 626 631 yes 2243063 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1833 Rhodococcus erythropolis Bacteria UP000035201 663763896 WP_030537967.1 497 497 yes 2243064 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487 Neisseria meningitidis Bacteria UP000050419 658477766 WP_029688070.1 625 635 yes 2243065 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 435910 Enterobacter pulveris Bacteria 657886539 WP_029590711.1 626 632 yes 2243066 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 213783 Shewanella waksmanii Bacteria 655366663 WP_028772714.1 639 648 yes 2243067 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35703 Citrobacter amalonaticus Bacteria UP000037074 763412337, 666375039 KEY45026.1 WP_044268702.1 625 633 yes 2243068 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1266909 Thioalkalivibrio sp. ALE19 Bacteria 655042581 WP_028491282.1 627 629 yes 2243069 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34010 Azospirillum halopraeferens Bacteria 655968792 WP_029011397.1 604 607 yes 2243070 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1935 Streptomyces violaceoruber Bacteria 664406512 WP_030932370.1 600 606 yes 2243071 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65058, 1408268 Corynebacterium ulcerans, Corynebacterium ulcerans FRC58 Bacteria UP000029905, UP000036185 661281986, 852474309, 700340522, 698969858 AKN77320.1, AIU92028.1, AIU30720.1 WP_029975454.1 556 569 yes 2243072 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68199 Streptomyces flavochromogenes Bacteria 663318120 WP_030317993.1 595 597 yes 2243073 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562, 1444223 Escherichia coli, Escherichia coli 3-267-03_S4_C1 Bacteria UP000036210, UP000027701 693094342, 658714684 KEJ56483.1 WP_032251646.1 626 631 yes 2243074 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 191960 Sedimenticola selenatireducens Bacteria 656109332 WP_029132873.1 627 627 yes 2243075 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 658997839, 820920013, 807104849, 655824394 KKX70913.1, KKC93473.1, KEF00033.1 WP_029833563.1 640 646 yes 2243076 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1456280 uncultured marine thaumarchaeote KM3_75_F06 Archaea 663526801 AIF16966.1 A0A075HKP7 A0A075HKP7_9ARCH 442 442 yes 2243077 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1748 Propionibacterium acidipropionici Bacteria UP000067247 655291303 WP_028700406.1 590 595 yes 2243078 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 273 274 no 2243079 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 913319 candidate division KSB1 bacterium SCGC AAA252-N11 Bacteria 658545308 WP_029738044.1 77 77 no 2243080 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463920 Streptomyces sp. NRRL S-87 Bacteria 663154163 WP_030193393.1 591 593 yes 2243081 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1130335 candidate division EM 19 bacterium JGI 0000106-N5 Bacteria 658441520 WP_029667465.1 130 131 no 2243082 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883, 1609135 Streptomyces sp. NRRL S-104 Bacteria UP000033571 664287161, 797025787 KJY23566.1 WP_030817017.1 592 595 yes 2243083 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 249567 Streptomyces hygroscopicus subsp. decoyicus Bacteria UP000037606 662124109 WP_030075819.1 589 593 yes 2268010 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 158852, 1005994 Trabulsiella guamensis, Trabulsiella guamensis ATCC 49490 Bacteria UP000028630 740323515, 668714941 KFC00603.1 WP_038160625.1 626 631 yes 2268011 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615 Serratia marcescens Bacteria UP000055021 727193591, 668656715 KFB54125.1 WP_033655323.1 632 647 yes 2268012 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 41202, 910964 Ewingella americana, Ewingella americana ATCC 33852 Bacteria UP000028640 736792787, 668960575 KFC78119.1 WP_034795028.1 634 652 yes 2268013 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84531 Lysobacter antibioticus Bacteria UP000064630 666657670 WP_031370342.1 628 630 yes 2268014 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 816 671548971 WP_031531925.1 575 575 yes 2268015 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1491 Clostridium botulinum Bacteria UP000030128 666655357 WP_031369308.1 345 345 no 2268016 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173365 Methylobacter tundripaludum Bacteria 670489348 WP_031437598.1 625 626 yes 2268017 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1549810 Microvirga sp. BSC39 Bacteria UP000028825 738403135, 672305211 KFG67890.1 WP_036354812.1 613 615 yes 2268018 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40576, 1398201 Xenorhabdus bovienii, Xenorhabdus bovienii str. puntauvense Bacteria UP000032930, UP000028511 740377386, 668988920 WP_038212464.1 625 657 yes 2268019 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 636, 667120 Edwardsiella tarda, Edwardsiella tarda 080813 Bacteria UP000035028, UP000028681 735673436, 672363185 AIJ08382.1 WP_034165780.1 627 643 yes 2268020 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 318464 Clostridium sulfidigenes Bacteria UP000028542 737144438, 666991571 KEZ86981.1 WP_035131624.1 437 437 yes 2268021 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554283 Flavobacterium chungangense Bacteria 670506574 WP_031454396.1 607 607 yes 2268022 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1265 Ruminococcus flavefaciens Bacteria 671582321 WP_031559783.1 437 437 yes 2268023 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1232437 Desulfobacula sp. TS Bacteria 670503276 WP_031451162.1 429 429 yes 2268024 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 215803 Enhygromyxa salina Bacteria UP000031599 747211985 KIG11697.1 545 561 yes 2268025 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1506587 Burkholderia sp. MSh1 Bacteria 667783389, 672437637 KFG94068.1 WP_031401863.1 642 643 yes 2268026 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66874 Streptomyces bicolor Bacteria 671494837 WP_031484728.1 592 594 yes 2268027 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 394096 Hyalangium minutum Bacteria UP000028725 763328399, 670623089 KFE69548.1 WP_044186839.1 621 624 yes 2268028 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 549 Pantoea agglomerans Bacteria UP000050560 671630940 WP_031594365.1 632 640 yes 2268029 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61435, 1432059 Dehalococcoides ethenogenes, Dehalococcoides mccartyi CG1 Bacteria UP000054393, UP000031781 752682889, 670942540 AII57862.1 WP_041330840.1 430 431 yes 2268030 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42345 Phoenix dactylifera Plants 672124070 XP_008785413.1 543 673 yes 2268031 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42345 Phoenix dactylifera Plants 672124074 XP_008785414.1 543 648 yes 2268032 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666 Vibrio cholerae Bacteria UP000028983 763263405, 669401827 KFE25821.1 WP_044127925.1 639 645 yes 2268033 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666 Vibrio cholerae Bacteria UP000028983 694138912, 669368857 KFD96967.1 WP_032477321.1 639 645 yes 2268034 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219045 Sphingobium herbicidovorans NBRC 16415 Bacteria UP000024284 672388547 KFG90249.1 619 632 yes 2268035 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1930 Streptomyces scabiei Bacteria UP000028707 739838641, 672104618 KFG02207.1 WP_037689581.1 599 614 yes 2268036 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 555, 180957 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. carotovorum, Pectobacterium carotovorum subsp. brasiliensis Bacteria UP000053038, UP000031378, UP000032867 746423709, 741143576, 741110403, 741109592, 741080563, 671737628 KHT35957.1, KHT03021.1, KHT02225.1, KHS73471.1, KFF68970.1 WP_039464279.1 631 651 yes 2268037 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 208439 Amycolatopsis japonica Bacteria UP000028492 667678758 AIG73374.1 544 547 yes 2268038 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666 Vibrio cholerae Bacteria UP000028983 694140201, 669354008 KFD83840.1 WP_032478537.1 639 645 yes 2268039 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 421531 Chryseobacterium luteum Bacteria UP000028703 736695790, 671224378 KFF09498.1 WP_034701385.1 603 603 yes 2268040 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 458197 Serratia nematodiphila Bacteria UP000028708 727159102, 672090928 KFF86953.1 WP_033631536.1 632 647 yes 2268041 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410630 Lachnospiraceae bacterium P6A3 Bacteria 671616459 WP_031585303.1 426 427 yes 2268042 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 196367 Burkholderia sordidicola Bacteria UP000054893 666646495 WP_031363844.1 641 643 yes 2268043 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 51288, 1006000 Kluyvera ascorbata, Kluyvera ascorbata ATCC 33433 Bacteria UP000028600 737931559, 668985631 KFC98603.1 WP_035896386.1 626 632 yes 2268044 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 403776 Sphingobacterium sp. PM2-P1-29 Bacteria 786218463, 672713763 WP_045752868.1 604 604 yes 2268045 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37919 Rhodococcus opacus Bacteria UP000028488 669182539 AII09000.1 541 548 yes 2268046 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410623 Lachnospiraceae bacterium FD2005 Bacteria 671579799 WP_031558059.1 434 435 yes 2268047 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615, 911022 Serratia marcescens, Serratia marcescens subsp. marcescens ATCC 13880 Bacteria UP000055021, UP000028633 727171786, 674736657, 669004782 KFL03654.1, KFD16179.1 WP_033638957.1 632 647 yes 2268048 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392005 Comamonas testosteroni TK102 Bacteria UP000028782 672609252 AIJ48223.1 625 654 yes 2268049 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1502851 Bosea sp. LC85 Bacteria UP000028622 759513698, 668954180 KFC72865.1 WP_043234158.1 618 620 yes 2268050 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686278311, 671045599 KFE96256.1 WP_031855395.1 640 646 yes 2268051 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 416213 Ferrovum myxofaciens Bacteria 671635046 WP_031596795.1 631 634 yes 2268052 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 930 Acidithiobacillus thiooxidans Bacteria 671594949 WP_031569689.1 627 628 yes 2268053 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 82977, 1006004 Buttiauxella agrestis, Buttiauxella agrestis ATCC 33320 Bacteria UP000028653 736470630, 668967777 KFC84855.1 WP_034492320.1 626 633 yes 2268054 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1408320 Lachnospiraceae bacterium AC2014 Bacteria 671563036 WP_031543609.1 433 434 yes 2268055 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1499086 Cronobacter sp. 1383 Bacteria 671539096 WP_031522797.1 626 632 yes 2268056 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1233950 Chryseobacterium sp. JM1 Bacteria UP000028731 736722553, 671235601 KFF20571.1 WP_034726940.1 603 603 yes 2268057 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 306205 Rheinheimera texasensis Bacteria 671596709 WP_031571106.1 586 600 yes 2268058 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 292407 Dyadobacter crusticola Bacteria 671546909 WP_031530333.1 627 627 yes 2268059 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 670465646 WP_031414425.1 640 646 yes 2268060 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1502852 Massilia sp. LC238 Bacteria UP000028601 738255401, 668953259 KFC71958.1 WP_036210509.1 636 637 yes 2268061 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1280380 Synechococcus sp. KORDI-100 Bacteria UP000028591 670926184 AII42146.1 474 486 yes 2268062 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1504981 Halomonas sp. KO116 Bacteria UP000028645 779739559 AJY51753.1 272 272 no 2268063 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 835592365, 670188853 KFE51637.1 WP_047574917.1 628 629 yes 2268064 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901 Salmonella enterica Bacteria UP000054489 671597325 WP_031571601.1 626 631 yes 2268065 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 135517 Geobacillus vulcani Bacteria 670457011 WP_031405810.1 562 562 yes 2268066 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 340956 Desulfovibrio frigidus Bacteria 671486044 WP_031480368.1 434 434 yes 2268067 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 180957 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. brasiliensis Bacteria UP000053038, UP000032867 746233255, 671737593 KFF68936.1 WP_039281859.1 631 651 yes 2268068 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1517681 Vibrio sp. ER1A Bacteria UP000028548 740390212, 667810822 KFA99644.1 WP_038224388.1 637 640 yes 2268069 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406 Paenibacillus polymyxa Bacteria UP000031922 670515354 WP_031462870.1 591 614 yes 2268070 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1301915 Methanocaldococcus sp. JH146 Archaea UP000028781 851372865, 672366425 AIJ05762.1 WP_048201915.1 A0A076LFW4 A0A076LFW4_9EURY 426 426 yes 2268071 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423 Bacillus subtilis Bacteria UP000030083 695807202, 668755507 KFC31379.1 WP_032721208.1 590 590 yes 2268072 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 138074 Serratia symbiotica Bacteria UP000042738 749664647, 669020542 WP_040263816.1 633 647 yes 2268073 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 558152 Chryseobacterium sp. CTM Bacteria UP000028709 736677781, 671243814 KFF28735.1 WP_034684146.1 603 603 yes 2268074 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1492737 Flavobacterium sp. EM1308 Bacteria UP000028636 737665538, 668937297 KFC60231.1 WP_035635152.1 607 607 yes 2268075 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 180957 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. brasiliensis Bacteria UP000053038, UP000032867 746228483, 671738342 KFF69668.1 WP_039277366.1 631 651 yes 2268076 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1504672 Polaromonas sp. CG9_12 Bacteria UP000043372 738920755, 669785000 WP_036807548.1 641 642 yes 2268077 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 695640765, 670180632 KFE43748.1 WP_032615439.1 627 629 yes 2268078 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36087 Trichuris trichiura Invertebrates UP000030665 669219034 362 1429 yes 2268079 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 362 362 no 2268080 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 667760815 WP_031382044.1 640 646 yes 2268081 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1492922 bacterium MFB021 Bacteria UP000028732 671420504 KFF48359.1 624 625 yes 2268082 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 156978 Corynebacterium imitans Bacteria UP000028780 740803637, 672594043 AIJ33020.1 WP_038588920.1 589 593 yes 2268083 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 13690 Sphingobium yanoikuyae Bacteria UP000028534 739664170, 666679548 KEZ18934.1 WP_037519474.1 624 631 yes 2268084 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1317124 Thioclava sp. 13D2W-2 Bacteria UP000028607 740310389, 669598653 KFE34212.1 WP_038147747.1 591 597 yes 2268085 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61435, 1432060 Dehalococcoides ethenogenes, Dehalococcoides mccartyi CG4 Bacteria UP000054393, UP000031772 752694106, 670944083 AII59404.1 WP_041341865.1 430 431 yes 2268086 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 416586 Selenomonas sp. WG Bacteria 671616759 WP_031585551.1 434 435 yes 2268087 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 991 Flavobacterium hydatis Bacteria UP000028712 737653753, 671230200 KFF15238.1 WP_035623645.1 607 607 yes 2268088 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1158292 Thiomonas sp. FB-Cd Bacteria 670457513 WP_031406312.1 623 624 yes 2268089 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 666 Vibrio cholerae Bacteria UP000028983 694135986, 669397489 KFE21988.1 WP_032475663.1 639 645 yes 2268090 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1232437 Desulfobacula sp. TS Bacteria 670503054 WP_031450942.1 422 434 yes 2268091 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 671501773 WP_031490007.1 440 451 yes 2268092 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 307480 Chryseobacterium vrystaatense Bacteria UP000028719 736736305, 671243626 KFF28550.1 WP_034740227.1 603 603 yes 2268093 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83771 Succinivibrio dextrinosolvens Bacteria 671504641 WP_031492045.1 487 515 yes 2268094 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 585423 Synechococcus sp. KORDI-49 Bacteria UP000028589 670930739 AII46700.1 479 483 yes 2268095 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29354 Clostridium celerecrescens Bacteria UP000028525 740445955, 666996229 KEZ91451.1 WP_038277802.1 434 435 yes 2268096 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554131 Thiomonas sp. CB2 Bacteria 668346294 624 669 yes 2268097 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463856 Streptomyces sp. NRRL F-5123 Bacteria 671528807 WP_031512658.1 588 589 yes 2268098 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 83655, 911008 Leclercia adecarboxylata, Leclercia adecarboxylata ATCC 23216 Bacteria UP000035908, UP000028621 695641602, 668978242 KFC92259.1 WP_032615902.1 626 631 yes 2268099 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1524267 Pseudomonas sp. BRG-100 Bacteria UP000028711 696302729, 671398614 KFF44500.1 WP_032878242.1 628 634 yes 2268100 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 13690 Sphingobium yanoikuyae Bacteria UP000028534 739652381, 669024237 KFD28321.1 WP_037508141.1 624 631 yes 2268101 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1491 Clostridium botulinum Bacteria UP000030128 666656965 WP_031369866.1 130 130 no 2268102 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1379700 Sphingomonas sp. STIS6.2 Bacteria 667774886 WP_031394038.1 631 640 yes 2268103 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1491 Clostridium botulinum Bacteria UP000030128 666655551 WP_031369380.1 125 125 no 2268104 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 317 Pseudomonas syringae Bacteria UP000028642 695678191, 670189282 KFE52051.1 WP_032631265.1 628 629 yes 2268105 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29486 Yersinia ruckeri Bacteria UP000058222 740411224, 788044413, 715583588, 669788532 AKA38474.1, KGX82837.1, KFE37872.1 WP_038244622.1 646 678 yes 2268106 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 472175 Nitratireductor basaltis Bacteria UP000053675 738534599, 667918482 KFB11259.1 WP_036483008.1 601 608 yes 2268107 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 585425 Synechococcus sp. KORDI-52 Bacteria UP000028593 670931941 AII47901.1 475 486 yes 2268108 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1517683 Chryseobacterium sp. P1-3 Bacteria UP000028723 671764200 KFF75889.1 603 603 yes 2268109 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1406225 Cystobacter violaceus Cb vi76 Bacteria UP000028547 667802032 KFA91570.1 609 610 yes 2268110 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1382303 Caulobacteraceae bacterium PMMR1 Bacteria 670498876 WP_031446827.1 604 610 yes 2268111 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287, 1262663 Pseudomonas aeruginosa, Pseudomonas aeruginosa VRFPA01 Bacteria UP000065817, UP000017814 730357606, 671386400 KFF33299.1 WP_033997514.1 627 627 yes 2268112 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1379701 Sphingomonas sp. FUKUSWIS1 Bacteria 670491083 WP_031439302.1 631 640 yes 2268113 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 718217, 1228987 cyanobacterium endosymbiont of Epithemia turgida, cyanobacterium endosymbiont of Epithemia turgida isolate ETSB Lake Yunoko Bacteria UP000031625 763236471, 667666794 WP_044106552.1 458 460 yes 2268114 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44060 Streptomyces megasporus Bacteria 671524260 WP_031508705.1 605 610 yes 2268115 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1337936 Calothrix sp. 336/3 Bacteria UP000065745 737164280, 817926303 AKG20791.1 WP_035150721.1 458 459 yes 2268116 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 569, 910996 Hafnia alvei, Hafnia alvei ATCC 13337 Bacteria UP000066243, UP000028605 759781713, 668973735 KFC88955.1 WP_043490377.1 631 648 yes 2268117 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1465 Brevibacillus laterosporus Bacteria 670466858, 817624064 AKF96292.1 WP_031415635.1 591 592 yes 2268118 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 438855 Methylococcaceae bacterium IT-4 Bacteria 670486777 WP_031435029.1 621 622 yes 2268119 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1504981 Halomonas sp. KO116 Bacteria UP000028645 737588489, 779739555 AJY51749.1 WP_035559380.1 629 629 yes 2268120 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67332 Streptomyces mutabilis Bacteria UP000029095 759664879, 672309807 KFG72345.1 WP_043382473.1 600 603 yes 2268121 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615 Serratia marcescens Bacteria UP000055021 759419823, 671765239 KFF76458.1 WP_043143687.1 632 647 yes 2268122 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423 Bacillus subtilis Bacteria UP000030083 671705333 KFF57255.1 590 590 yes 2268123 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28051 Lachnospira multipara Bacteria 671578096 WP_031556781.1 438 438 yes 2268124 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 258230 Frankia sp. CeD Bacteria UP000028546 737945855, 666858845 KEZ36753.1 WP_035909887.1 627 662 yes 2268125 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1354240 Riemerella anatipestifer CH3 Bacteria UP000028496 668354603 AIH03181.1 436 436 yes 2268126 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1244531 Campylobacter sp. 1485E Bacteria UP000064469 740668016, 669187882 AII14335.1 WP_038453306.1 449 450 yes 2268127 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 159290 Desulfonatronum thiodismutans Bacteria UP000027425 667766261 WP_031387220.1 433 434 yes 2268128 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2371 Xylella fastidiosa Bacteria UP000028529 667412426 KFA40784.1 596 603 yes 2268129 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1178777 Halomonas sp. B6 Bacteria 667763198 WP_031384262.1 634 634 yes 2268130 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1200567 Ruminobacter sp. RM87 Bacteria 671607239 WP_031579202.1 550 558 yes 2268131 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1445613 Sciscionella sp. SE31 Bacteria 670517214 WP_031464688.1 531 539 yes 2268132 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1499966 bacterium UASB14 Bacteria UP000030700 780192543, 672394364 WP_045509077.1 420 420 yes 2268133 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1247963 Parvularcula sp. JLT2013 Bacteria 671569692 WP_031549737.1 626 640 yes 2268134 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 671501394 WP_031489815.1 203 222 no 2268135 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 360054 Acidobacteria bacterium MPL3 Bacteria 671512305 WP_031498367.1 523 523 yes 2268136 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 362418 Flavobacterium sp. WB 3.2-61 Bacteria UP000028715 737716992, 671221739 KFF06878.1 WP_035685838.1 607 607 yes 2268137 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1304275 Salinisphaera hydrothermalis C41B8 Bacteria UP000028302 666934004 KEZ76463.1 614 614 yes 2268138 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1357268 Enterobacter sp. EGD-HP1 Bacteria UP000028382 695706592, 667745656 KFA83960.1 WP_032641546.1 626 631 yes 2277402 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 645 Aeromonas salmonicida Bacteria UP000052231 759410894, 675526084 KFN20687.1 WP_043134937.1 644 677 yes 2277403 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1499107 Smithella sp. SCADC Bacteria UP000029283 739523916, 676550577 KFO68642.1 WP_037383139.1 423 423 yes 2277404 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1001886 Vibrio sp. C7 Bacteria UP000029225 684605821 424 425 no 2277405 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1001886 Vibrio sp. C7 Bacteria UP000029225 684605822 198 203 no 2277406 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1693 Bifidobacterium minimum Bacteria UP000029014 672977683 KFI73041.1 588 911 yes 2277407 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1683, 518635 Bifidobacterium angulatum, Bifidobacterium angulatum DSM 20098 Bacteria UP000029105, UP000035066 705429413, 672943050, 781871152 KFI38798.1 WP_033508598.1 630 856 yes 2277408 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 186490 Candidatus Baumannia cicadellinicola Bacteria UP000067325 684175980 AIN46936.1 611 617 yes 2277409 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 265668 Vibrio ponticus Bacteria UP000029122 678237938 161 166 no 2277410 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 265668 Vibrio ponticus Bacteria UP000029122 678237937 336 338 no 2277411 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1505933 Mesorhizobium sp. ORS3359 Bacteria UP000041213 756829557, 685103243 WP_042646643.1 612 614 yes 2277412 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1549812 Massilia sp. BSC265 Bacteria UP000028843 738294112, 672864515 KFI07380.1 WP_036247826.1 636 637 yes 2277413 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1473546 Lysinibacillus sp. BF-4 Bacteria UP000029097 738190474, 674783084 KFL42504.1 WP_036146538.1 593 593 yes 2277414 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550, 1333849, 1333851 Enterobacter cloacae, Enterobacter cloacae ECNIH1, Enterobacter cloacae ECNIH3 Bacteria UP000036177, UP000029075, UP000029054 740629549, 723224853, 682113434, 682108870 AIX57501.1, AIN26364.1, AIN21020.1 WP_038415060.1 626 631 yes 2277415 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 672850091 KFH93380.1 626 631 yes 2277416 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1105367 Rhodobacter sp. DW2-9 Bacteria UP000028824 738744147, 672896053 KFI25735.1 WP_036638038.1 597 604 yes 2277417 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1502290 Marine Group I thaumarchaeote SCGC AAA799-D07 Archaea 851143782, 675346507 KFM19453.1 WP_048084218.1 A0A087S149 A0A087S149_9ARCH 441 442 yes 2277418 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1515746 Shewanella sp. YQH10 Bacteria UP000029264 739581550, 683414314 KFZ38373.1 WP_037439515.1 624 630 yes 2277419 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1718 Corynebacterium glutamicum Bacteria UP000031556 740798535, 674167781, 674156510 AIK84980.1, AIK87764.1 WP_038583818.1 597 598 yes 2277420 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686259751 WP_031842834.1 242 248 no 2277421 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686259752 WP_031842835.1 398 398 no 2277422 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1537915 Sulfurospirillum sp. SCADC Bacteria UP000029010 740109205, 674769824 KFL34289.1 WP_037958162.1 621 622 yes 2277423 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287 Pseudomonas aeruginosa Bacteria UP000065817 686123145 WP_031769207.1 568 568 yes 2277424 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1525753 Streptomyces sp. JS01 Bacteria UP000029064 695868944, 674715152 KFK89763.1 WP_032781759.1 593 596 yes 2277425 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 672830373 KFH74892.1 427 429 yes 2277426 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2162, 1641383 Methanobacterium formicicum, Methanobacterium sp. 42_16 Archaea UP000062768, UP000054221 851111738, 693276938, 683510538 AIS32945.1 WP_048073010.1 A0A090JWF9, A0A101HE19 A0A090JWF9_METFO, A0A101HE19_9EURY 424 424 yes 2277427 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1437603 Bifidobacterium mongoliense DSM 21395 Bacteria UP000029082 672979473 KFI74793.1 634 870 yes 2277428 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1430331 Geobacillus sp. G1w1 Bacteria UP000029267 696478719, 679865033 KFX36182.1 WP_033018127.1 563 563 yes 2277429 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 96345, 1452725 Flavobacterium psychrophilum, Flavobacterium psychrophilum FPG101 Bacteria UP000055977, UP000029242 740718019, 684208639 AIN70925.1 WP_038503305.1 607 607 yes 2277430 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901 Salmonella enterica Bacteria UP000054489 446247826 WP_000325681.1 483 485 yes 2277431 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 69974 Mesorhizobium plurifarium Bacteria UP000046122 751300648, 685122191 WP_041009171.1 612 614 yes 2277432 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 672 Vibrio vulnificus Bacteria UP000054370 746411095, 695264553 KGK68506.1 WP_039452535.1 639 647 yes 2277433 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 486, 546265 Neisseria lactamica, Neisseria lactamica ATCC 23970 Bacteria UP000029053 738526864, 673469322 KFJ35952.1 WP_036475325.1 625 633 yes 2277434 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 754436 Photobacterium sp. CECT 7614 Bacteria UP000036426 684145123 644 647 yes 2277435 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 983706, 1437610 Bifidobacterium sp. AFB22-1, Bifidobacterium reuteri DSM 23975 Bacteria UP000028984 763217889, 672989779 KFI84998.1 WP_044090340.1 638 918 yes 2277436 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1695 Bifidobacterium longum subsp. suis Bacteria UP000029024 672973155 KFI68560.1 619 621 yes 2277437 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 95486 Burkholderia cenocepacia Bacteria UP000065887 749320733, 685654590 AIO41720.1 WP_040143844.1 642 643 yes 2277438 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 237609 Pseudomonas alkylphenolia Bacteria UP000028931 740829975, 675323632 AIL63961.1 WP_038615258.1 628 629 yes 2277439 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 584 Proteus mirabilis Bacteria UP000033762 739026002, 721594282, 685235402 KGZ37550.1, KGA92014.1 WP_036907192.1 620 650 yes 2277440 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 555 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. carotovorum Bacteria UP000053038, UP000031378 746447820, 679627925 KFX10341.1 WP_039487720.1 631 654 yes 2277441 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 178901 Acetobacter malorum Bacteria UP000029092 759858507, 674839922 KFL92222.1 WP_043549401.1 607 624 yes 2277442 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 762211 Bifidobacterium sp. AFB23-3 Bacteria UP000029004 736510970, 673003785 KFI98823.1 WP_034527002.1 638 916 yes 2277443 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 69974 Mesorhizobium plurifarium Bacteria UP000046122 751273713, 685100649 WP_040982583.1 612 614 yes 2277444 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1427749 Amycolatopsis sp. MJM2582 Bacteria UP000053078 739476412, 683983809 KFZ84241.1 WP_037336307.1 536 538 yes 2277445 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29343 Clostridium cellulosi Bacteria UP000032431 769952604, 673067590 WP_045085791.1 445 447 yes 2277446 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 545 Citrobacter koseri Bacteria UP000053089 673533985 626 631 yes 2277447 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46914 Devosia riboflavina Bacteria UP000028981 737097558, 674764579 KFL29708.1 WP_035085863.1 607 609 yes 2277448 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1593232 Enterobacteriaceae bacterium ATCC 29904 Bacteria 749019102, 685449813 KGB10623.1 WP_040077667.1 626 631 yes 2277449 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1150460 Bifidobacterium kashiwanohense JCM 15439 Bacteria UP000035705 672970012, 757808247 KFI65462.1 603 879 yes 2277450 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3711 Brassica rapa Plants 685307294 XP_009144359.1 564 646 4N7Q, 4S29, 4S28, 4S27, 4S26, 4S25 yes 2277451 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55207 Pectobacterium betavasculorum Bacteria UP000032869 746260433, 679630873 KFX13152.1 WP_039308676.1 631 651 yes 2277452 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 244366 Klebsiella variicola Bacteria UP000037523 757719814, 674224432 KFJ97846.1 WP_042948014.1 626 631 yes 2277453 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 78398 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. odoriferum Bacteria UP000053038, UP000029439 763349618, 685002648 KGA39955.1 WP_044207866.1 631 651 yes 2277454 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28099, 1220582 Agrobacterium rubi, Rhizobium rubi NBRC 13261 Bacteria UP000028701 771645128, 674255204 WP_045230812.1 601 607 yes 2277455 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 566552 Bifidobacterium catenulatum DSM 16992 Bacteria UP000029016 672957970, 781877474 KFI53564.1 603 879 yes 2277456 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1390 Bacillus amyloliquefaciens Bacteria UP000027101 696298626, 679908908 KFX38018.1 WP_032874176.1 590 590 yes 2277457 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 488142 Serratia sp. SCBI Bacteria UP000028998 757520239, 676307445 AIM19901.1 WP_042783474.1 632 647 yes 2277458 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 160660 Thiobacillus prosperus Bacteria UP000029273 740252879, 684047827 KFZ89012.1 WP_038093718.1 625 629 yes 2277459 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 990268 Vibrio sp. R-40493 Bacteria UP000029228 684595392 246 249 no 2277460 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 990268 Vibrio sp. R-40493 Bacteria UP000029228 684595393 353 387 no 2277461 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1405 Bacillus mycoides Bacteria UP000035933 727344193, 675495298 KFN12846.1 WP_033798200.1 586 586 yes 2277462 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1505932 Mesorhizobium sp. ORS3324 Bacteria UP000038972 751262975, 685090478 WP_040972756.1 612 614 yes 2277463 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 1267545, 555 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. carotovorum ICMP 5702, Pectobacterium carotovorum subsp. carotovorum Bacteria UP000053038, UP000036108, UP000031378 746436071, 848447802, 679614699 KML72390.1, KFW97668.1 WP_039476337.1 631 659 yes 2277464 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1440054 Vibrio sp. OY15 Bacteria UP000029059 727824192, 673916400 KFJ85299.1 WP_033907327.1 640 646 yes 2277465 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1535750 Thermoactinomyces sp. Gus2-1 Bacteria UP000029276 740146854, 683422243 KFZ41449.1 WP_037992944.1 596 607 yes 2277466 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29486, 527005 Yersinia ruckeri, Yersinia ruckeri ATCC 29473 Bacteria UP000058222, UP000054139 740418218, 685056724, 731157168 KGA47873.1 WP_038251139.1 646 678 yes 2277467 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1405 Bacillus mycoides Bacteria UP000035933 757760044, 675481291 KFM99022.1 WP_042980930.1 586 586 yes 2277468 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630 Yersinia enterocolitica Bacteria UP000029427 696333442, 685189805 KGA77348.1 WP_032908750.1 634 655 yes 2277469 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 287 Pseudomonas aeruginosa Bacteria UP000065817 686117504 WP_031766531.1 310 310 no 2277470 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173452, 1173445 Salmonella enterica, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000198, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000224 Bacteria UP000054489, UP000029165, UP000029202 835613208, 677894865, 677796705 KFU07563.1, KFT14978.1 WP_047584142.1 341 343 yes 2277471 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1487956 Corynebacterium sp. 6931 Bacteria UP000029247 740843017, 685193337 AIN81503.1 WP_038628270.1 561 568 yes 2277472 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1487582 Peptococcaceae bacterium SCADC Bacteria UP000028991 754485013, 672907524 KFI36641.1 WP_041902233.1 300 300 no 2277473 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 401472 Corynebacterium ureicelerivorans Bacteria UP000028939 740824840, 675824676 AIL96366.1 WP_038610123.1 174 189 no 2277474 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686277312 WP_031854911.1 195 201 no 2277475 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 28901, 1173452, 1173445 Salmonella enterica, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000198, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000224 Bacteria UP000054489, UP000029165, UP000029202 835613942, 677892534, 677796760 KFU05409.1, KFT15027.1 WP_047584347.1 291 294 no 2277476 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1472345, 1072685 Basilea psittacipulmonis, Alcaligenaceae bacterium DSM 24701 Bacteria UP000028945 740713921, 675107582 AIL32502.1 WP_038499208.1 619 624 yes 2277477 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 762210, 1437607 Bifidobacterium sp. AFB23-1, Bifidobacterium saguini DSM 23967 Bacteria UP000029066 727802269, 672999123 KFI94219.1 WP_033889734.1 636 913 yes 2277478 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1460371 Amycolatopsis lurida NRRL 2430 Bacteria UP000029326 755909956 AJK53534.1 532 534 yes 2277479 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 990268 Vibrio sp. R-40493 Bacteria UP000029228 684609891 71 72 no 2277480 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 990268 Vibrio sp. R-40493 Bacteria UP000029228 684609892 394 396 no 2277481 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 948077, 1384056 Arenimonas sp. CF5-1, Arenimonas metalli CF5-1 Bacteria UP000029393 736079965, 675593521 KFN45233.1 WP_034213454.1 624 627 yes 2277482 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1173424 Salmonella enterica, Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000181 Bacteria UP000054489, UP000029170 835669066, 677952079 KFU61526.1 WP_047607403.1 626 631 yes 2277483 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3708 Brassica napus Plants UP000028999 674878687 565 646 4N7Q, 4S29, 4S28, 4S27, 4S26, 4S25 yes 2277484 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 549 Pantoea agglomerans Bacteria UP000050560 727325848, 674799286 KFL56663.1 WP_033780882.1 632 640 yes 2277485 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 95486 Burkholderia cenocepacia Bacteria UP000065887 749302877, 685644466 AIO31600.1 WP_040127042.1 642 643 yes 2277486 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 633150 Pseudomonas sp. 1-7 Bacteria UP000029037 674102929 KFJ92188.1 626 626 yes 2277487 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1538644 Sphingobacterium sp. ML3W Bacteria UP000028992 740911508, 676327865 AIM36366.1 WP_038696755.1 604 604 yes 2277488 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1028989 Pseudomonas sp. StFLB209 Bacteria UP000031652 676256790 628 630 yes 2277489 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386, 1423, 96241, 1549811 Bacillus subtilis, Bacillus subtilis subsp. spizizenii, Bacillus sp. BSC154 Bacteria UP000030083, UP000031422, UP000028985 695813476, 772685841, 745817893, 674559405, 672862061 AJW87541.1, AJD38562.1, KFK80261.1, KFI04940.1 WP_032727350.1 590 590 yes 2277490 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 613, 1524467, 1532556 Serratia sp. Ag, Serratia sp. Ag2 Bacteria UP000029043, UP000029111 739545235, 674723580, 674722447 KFK93626.1, KFK92565.1 WP_037403564.1 634 647 yes 2277491 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686140637 WP_031777125.1 162 168 no 2277492 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287 Pseudomonas aeruginosa Bacteria UP000065817 686104699 WP_031759650.1 571 571 yes 2277493 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 562 Escherichia coli Bacteria UP000036210 672854086 KFH97212.1 282 285 no 2277494 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 672834506 KFH78764.1 626 631 yes 2277495 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40754 Thioploca ingrica Bacteria UP000031623 780107112, 686205335 WP_045475427.1 620 624 yes 2277496 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686219296 WP_031820130.1 613 619 yes 2277497 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78343 Bifidobacterium boum Bacteria UP000029093 672952885 KFI48561.1 596 907 yes 2277498 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 104102 Acetobacter tropicalis Bacteria UP000029448 685625208 KGB23017.1 607 621 yes 2277499 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 662, 190893, 1526762 Vibrio coralliilyticus, Vibrio sp. B183 Bacteria UP000033403, UP000029061 740327925, 703565191, 672866460 AIW17568.1, KFI09277.1 WP_038164780.1 640 646 yes 2277500 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 585 Proteus vulgaris Bacteria UP000029433 739062558, 685170213 KGA57886.1 WP_036933969.1 620 650 yes 2277501 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1461583 Lysinibacillus sp. 13S34_air Bacteria 674647863 592 592 yes 2277502 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 762212, 1437608 Bifidobacterium sp. AFB23-4, Bifidobacterium biavatii DSM 23969 Bacteria UP000029108 705398204, 672958362 KFI53952.1 WP_033495164.1 650 881 yes 2277503 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1537917 Sulfuricurvum sp. MLSB Bacteria UP000029313 740099725, 675587272 KFN39271.1 WP_037948871.1 456 457 yes 2277504 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 69974 Mesorhizobium plurifarium Bacteria UP000046122 751294554, 685114763 WP_041003170.1 612 614 yes 2277505 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 878220 Chryseobacterium sp. StRB126 Bacteria UP000031650 780174877, 674274360 WP_045501392.1 603 603 yes 2277506 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287 Pseudomonas aeruginosa Bacteria UP000065817 686115916 WP_031765748.1 316 316 yes 2277507 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 990271 Vibrio variabilis Bacteria UP000030520 684619234 565 586 no 2277508 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 178606 Leptospirillum ferriphilum Bacteria UP000029452 738126158, 685241665 KGA92562.1 WP_036084088.1 458 462 yes 2277509 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28031 Lysinibacillus fusiformis Bacteria UP000029429 738192160, 685219556 KGA81667.1 WP_036148152.1 592 592 yes 2277510 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1402 Bacillus licheniformis Bacteria UP000036721 737357241, 675471696 KFM89518.1 WP_035339446.1 591 591 yes 2277511 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78327, 1388763 Pseudomonas mosselii, Pseudomonas mosselii SJ10 Bacteria UP000018178 740921654, 684198298 AIN60527.1 WP_038706901.1 625 626 yes 2277512 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 180957 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. brasiliensis Bacteria UP000053038, UP000032867 746263388, 684997240 KGA34891.1 WP_039311331.1 631 651 yes 2277513 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1522072 Sphingobium sp. ba1 Bacteria UP000029094 739620447, 674788904 KFL48100.1 WP_037476958.1 632 643 yes 2277514 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1505946 Mesorhizobium sp. SOD10 Bacteria UP000045063 685084369 609 613 yes 2277515 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 3708 Brassica napus Plants UP000028999 674887195 564 646 4N7Q, 4S29, 4S28, 4S27, 4S26, 4S25 yes 2277516 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1502295 Marine Group I thaumarchaeote SCGC AAA799-P11 Archaea 675346967 KFM19901.1 A0A087S2E7 A0A087S2E7_9ARCH 438 438 yes 2277517 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78345 Bifidobacterium merycicum Bacteria UP000029060 705460505, 672975244 KFI70632.1 WP_033523614.1 611 856 yes 2277518 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287 Pseudomonas aeruginosa Bacteria UP000065817 686194027 WP_031805938.1 627 627 yes 2277519 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 835742794, 678153798 KFV22386.1 WP_047642904.1 626 631 yes 2277520 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78346 Bifidobacterium ruminantium Bacteria UP000029078 705404952, 672995430 KFI90586.1 WP_033498833.1 615 873 yes 2277521 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 672 Vibrio vulnificus Bacteria UP000054370 746505238, 674429895 KFK48611.1 WP_039542439.1 639 647 yes 2277522 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1505946 Mesorhizobium sp. SOD10 Bacteria UP000045063 751295316, 685081301 WP_041003916.1 608 612 yes 2277523 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 670 Vibrio parahaemolyticus Bacteria UP000028114 686280584 WP_031857176.1 120 126 no 2277524 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 60550 Burkholderia pyrrocinia Bacteria UP000029106 736009271, 674794228 KFL51625.1 WP_034183180.1 642 643 yes 2277525 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1499686 Pseudomonas sp. 20_BN Bacteria UP000053902 739159719, 685079484 WP_037023909.1 626 626 yes 2277526 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1461581 Pseudomonas sp. 12M76_air Bacteria 764929306, 683399663, 674643091 WP_044500077.1 625 627 yes 2277527 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 218140 Bifidobacterium psychraerophilum Bacteria UP000029050 672987109 KFI82359.1 605 624 yes 2277528 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55207 Pectobacterium betavasculorum Bacteria UP000032869 746278428, 679616543 KFW99394.1 WP_039326005.1 631 651 yes 2277529 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 554, 78398 Pectobacterium carotovorum, Pectobacterium carotovorum subsp. odoriferum Bacteria UP000053038, UP000029439 746455216, 684991079 KGA28864.1 WP_039494834.1 631 651 yes 2277530 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 672 Vibrio vulnificus Bacteria UP000054370 746512901, 674434804 KFK53038.1 WP_039549544.1 639 647 yes 2277531 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1773 Mycobacterium tuberculosis Bacteria UP000065426 686055595 WP_031737795.1 229 231 no 2277532 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396 Bacillus cereus Bacteria UP000036076 727232502, 674832872 KFL85361.1 WP_033693282.1 586 586 yes 2277533 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 375061, 1121014 Arenimonas donghaensis, Arenimonas donghaensis DSM 18148 = HO3-R19 Bacteria UP000029085 736087902, 674772946 KFL37354.1 WP_034221271.1 624 627 yes 2277534 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354197, 1384054 Arenimonas malthae, Arenimonas malthae CC-JY-1 Bacteria UP000029392 760122575, 675593947 KFN45632.1 WP_043804094.1 624 627 yes 2277535 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 401472 Corynebacterium ureicelerivorans Bacteria UP000028939 740824855, 675824682 AIL96372.1 WP_038610138.1 597 599 yes 2277536 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 629, 28152, 1454377 Yersinia kristensenii, Yersinia frederiksenii Y225 Bacteria UP000041188, UP000031898 740853194, 755435449, 755288783, 682105607 AJJ35574.1, AJI86237.1, AIN17483.1 WP_038638447.1 646 676 yes 2277537 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2162 Methanobacterium formicicum Archaea UP000062768 693274979, 683510479 AIS30986.1 A0A090I938 A0A090I938_METFO 429 429 yes 2277538 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 672852429 KFH95596.1 396 398 yes 2277539 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 762209, 1437609 Bifidobacterium sp. AFB22-5, Bifidobacterium callitrichos DSM 23973 Bacteria UP000029072 759445164, 672960910 KFI56465.1 WP_043167152.1 636 915 yes 2277540 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1288 Staphylococcus xylosus Bacteria UP000032432 827010428, 683405159 WP_047172941.1 578 578 yes 2291849 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 107637 Methylomonas sp. LW13 Bacteria 697072381 WP_033155840.1 621 622 yes 2291850 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1552758 Xanthomonas sp. Nyagatare Bacteria UP000029879 835882867, 695204531 KGK56588.1 WP_047696931.1 624 625 yes 2291851 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1513, 1172203 Clostridium tetani, Clostridium tetani ATCC 9441 Bacteria UP000029689, UP000029730 737122550, 693307364 KGI40572.1 WP_035110238.1 438 438 yes 2291852 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1548150 Helicobacter sp. MIT 05-5294 Bacteria UP000029926 696189453 KGL32019.1 100 100 no 2291853 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 935199 Rhodococcus sp. p52 Bacteria 696565723 WP_033097551.1 571 574 yes 2291854 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 294, 1324332 Pseudomonas fluorescens, Pseudomonas fluorescens LMG 5329 Bacteria UP000060991, UP000030060 742365261, 689663460 KGE68546.1 WP_038844449.1 628 629 yes 2291855 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 457395 Bacteroides sp. 9_1_42FAA Bacteria UP000005103 696358894 WP_032934046.1 566 566 yes 2291856 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1076550 Pantoea rwandensis Bacteria UP000029495 740858493, 691220849 AIR84134.1 WP_038643745.1 631 641 yes 2291857 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 46206 Pseudobutyrivibrio ruminis Bacteria 697064890 WP_033154472.1 434 435 yes 2291858 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 80852 Aliivibrio wodanis Bacteria UP000032427 769984873, 692305232 WP_045100854.1 640 644 yes 2291859 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1321945 Coxiella burnetii str. Namibia Bacteria UP000029903 697780198 AIT62822.1 531 531 yes 2291860 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 225117 Pyrus x bretschneideri Plants 694440076, 694440072 XP_009346876.1, XP_009346875.1 550 648 yes 2291861 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413503 Cronobacter malonaticus Bacteria 696400673 WP_032972713.1 626 633 yes 2291862 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1055352 Streptomyces sp. W007 Bacteria UP000004626 695891810 WP_032792899.1 587 606 yes 2291863 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28229 Colwellia psychrerythraea Bacteria UP000029843 696561888 WP_033093763.1 650 652 yes 2291864 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 173, 57678 Leptospira interrogans, Leptospira interrogans serovar Lai Bacteria UP000037872, UP000029735 757477397, 689451089 KGE24905.1 WP_042752338.1 441 495 yes 2291865 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423 Bacillus subtilis Bacteria UP000030083 695815508 WP_032729355.1 440 440 yes 2291866 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413503 Cronobacter malonaticus Bacteria 696424980 WP_032994760.1 626 633 yes 2291867 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219 Prochlorococcus marinus Bacteria 695326882 WP_032525122.1 453 456 yes 2291868 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 340146 Exiguobacterium mexicanum Bacteria UP000029697 736781336, 693727899 KGI83327.1 WP_034784033.1 122 122 no 2291869 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449050 Clostridium sp. KNHs205 Bacteria 697199356 WP_033168097.1 433 433 yes 2291870 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 696258904 WP_032836572.1 609 881 yes 2291871 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 189426 Paenibacillus odorifer Bacteria UP000029501 740788114, 686565924 AIQ76617.1 WP_038573398.1 580 580 yes 2291872 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219 Prochlorococcus marinus Bacteria 695323617 WP_032521928.1 433 436 yes 2291873 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1487923 Desulfosporosinus sp. HMP52 Bacteria UP000029916 736585582, 695886406 KGK92038.1 WP_034596522.1 422 432 yes 2291874 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1487923 Desulfosporosinus sp. HMP52 Bacteria UP000029916 736585581, 695886405 KGK92037.1 WP_034596521.1 419 425 yes 2291875 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1479485 Tolypothrix bouteillei Iicb1 Bacteria UP000029738 744449595 KIE10338.1 455 458 yes 2291876 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28229 Colwellia psychrerythraea Bacteria UP000029843 694339731 KGJ92676.1 650 662 yes 2291877 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1471467 Prochlorococcus sp. scB241_529J16 Bacteria 695482416 WP_032574218.1 72 72 no 2291878 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 694146664 WP_032483609.1 429 440 yes 2291879 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 381 Mesorhizobium loti Bacteria UP000053176 696343027 WP_032918179.1 601 616 yes 2291880 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 696258742 WP_032836415.1 609 881 yes 2291881 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 696264944 WP_032842057.1 609 872 yes 2291882 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67269 Streptomyces alboviridis Bacteria 695842537 WP_032755836.1 592 600 yes 2291883 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 268407 Paenibacillus wynnii Bacteria UP000029734 738756707, 689314989 KGE19352.1 WP_036650230.1 595 595 yes 2291884 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1487922 Pseudomonas sp. HMP271 Bacteria UP000029837 759578943, 695876799 KGK82787.1 WP_043297854.1 627 627 yes 2291885 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29495 Vibrio navarrensis Bacteria UP000029860 746378579, 694865477 KGK09878.1 WP_039422258.1 639 645 yes 2291886 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 158822 Cedecea neteri Bacteria UP000029509 746240771, 690277623 AIR60305.1 WP_039289265.1 626 633 yes 2291887 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29495 Vibrio navarrensis Bacteria UP000029860 746420303, 694873205 KGK17237.1 WP_039460986.1 639 645 yes 2291888 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1542468 Enterobacter sp. UCD-UG_FMILLET Bacteria UP000029703 835756427, 693449017 KGI63458.1 WP_047651714.1 626 631 yes 2291889 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 607 607 yes 2291890 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 221126 Algibacter lectus Bacteria UP000029643 693571784 274 274 no 2291891 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 221126 Algibacter lectus Bacteria UP000029643 693571783 202 202 no 2291892 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216142 Pseudomonas rhizosphaerae Bacteria UP000029499 759469912, 692344866 AIS18482.1 WP_043191222.1 633 634 yes 2291893 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216 Helicobacter muridarum Bacteria UP000029922 736544645, 696166847 KGL13525.1 WP_034558247.1 448 449 yes 2291894 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 381 Mesorhizobium loti Bacteria UP000053176 696342338 WP_032917490.1 596 611 yes 2291895 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 158822 Cedecea neteri Bacteria UP000029509 746251046, 690282067 AIR64717.1 WP_039299379.1 626 633 yes 2291896 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1499504, 1499503, 1499502 Prochlorococcus sp. MIT 0703, Prochlorococcus sp. MIT 0702, Prochlorococcus sp. MIT 0701 Bacteria UP000030371, UP000030450, UP000030412 691711074, 691707414, 691703020 KGG33986.1, KGG30477.1, KGG26288.1 453 454 yes 2291897 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1501145, 1497020 Neosynechococcus sphagnicola, Neosynechococcus sphagnicola sy1 Bacteria UP000030170 738624242, 691246708 KGF72409.1 WP_036533846.1 456 457 yes 2291898 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 381 Mesorhizobium loti Bacteria UP000053176 696350732 WP_032925884.1 598 611 yes 2291899 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1907 Streptomyces glaucescens Bacteria UP000029482 759795913, 692323120 AIR99323.1 WP_043502311.1 594 601 yes 2291900 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36874 Porphyromonas cangingivalis Bacteria UP000029825 738962588, 696210332 KGL49421.1 WP_036846475.1 596 597 yes 2291901 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29495 Vibrio navarrensis Bacteria UP000029860 746394995, 694872931 KGK16976.1 WP_039437623.1 639 645 yes 2291902 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 116090, 1156417 Caloranaerobacter azorensis, Caloranaerobacter sp. H53214 Bacteria UP000029622 737177832, 692238472 KGG80059.1 WP_035163953.1 437 437 yes 2291903 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 694148295 WP_032485240.1 424 435 yes 2291904 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285 Comamonas testosteroni Bacteria UP000029609 736343120, 692399648 KGH30200.1 WP_034369185.1 625 647 yes 2291905 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 558884 Aeromonas sp. AE122 Bacteria 696586229 WP_033112528.1 645 663 yes 2291906 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 153721 Sporocytophaga myxococcoides Bacteria UP000030185 780091873, 695124951 WP_045468620.1 619 619 yes 2291907 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285 Comamonas testosteroni Bacteria UP000029609 736363973, 692397848, 692397496, 692376130 KGH28415.1, KGH28074.1, KGH07327.1 WP_034389497.1 625 647 yes 2291908 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111105 Porphyromonas gulae Bacteria UP000029876 746374012, 696210915 KGL49990.1 WP_039418074.1 587 587 yes 2291909 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1449047 Bacillus sp. UNC69MF Bacteria 696295408 WP_032871015.1 590 590 yes 2291910 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1548150 Helicobacter sp. MIT 05-5294 Bacteria UP000029926 696193285 KGL34804.1 283 283 no 2291911 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 214687 Musa acuminata subsp. malaccensis Plants UP000012960 695039998 XP_009407556.1 543 703 yes 2291912 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 283, 285 Comamonas testosteroni Bacteria UP000029609 736385368, 692350656 KGG82429.1 WP_034409654.1 625 647 yes 2291913 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 173 Leptospira interrogans Bacteria UP000037872 446607852 WP_000685198.1 77 77 no 2291914 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 907 Megasphaera elsdenii Bacteria UP000029696 738249374, 693738252 KGI88878.1 WP_036204555.1 433 433 yes 2291915 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28152 Yersinia kristensenii Bacteria UP000041188 696241753 WP_032821183.1 639 665 yes 2291916 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1491 Clostridium botulinum Bacteria UP000030128 696530979 WP_033064500.1 252 252 no 2291917 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 658612 Pseudomonas sp. H2 Bacteria UP000029716 835606083, 693762795 KGI93957.1 WP_047582283.1 625 626 yes 2291918 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66269, 66270 Pantoea stewartii, Pantoea stewartii subsp. indologenes Bacteria UP000030462, UP000029606 727279864, 687261814 KGD84867.1 WP_033737960.1 632 640 yes 2291919 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1120705 Sphingopyxis sp. LC363 Bacteria UP000029625 739701220, 686474674 KGB57578.1 WP_037555457.1 621 630 yes 2291920 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1284775 Prevotella sp. S7-1-8 Bacteria UP000029597 739011317, 690770228 KGF17935.1 WP_036892822.1 524 524 yes 2291921 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219, 167549 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9321 Bacteria UP000030578 695318739, 691679240 KGG03186.1 WP_032517944.1 452 456 yes 2291922 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1543375 Aeromonas sp. 4287D Bacteria 696649629 WP_033135079.1 645 663 yes 2291923 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 426 426 yes 2291924 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1200547 Prevotella sp. RM4 Bacteria 697061784 WP_033151395.1 527 528 yes 2291925 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1513 Clostridium tetani Bacteria UP000029689 737154685, 693309379 KGI42524.1 WP_035141538.1 438 438 yes 2291926 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1284708 Clostridiales bacterium S7-1-4 Bacteria UP000029539 736531648, 690759085 KGF07594.1 WP_034546449.1 432 432 yes 2291927 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 582 Morganella morganii Bacteria UP000037663 692182650 WP_032099157.1 620 649 yes 2291928 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1519438 Eubacterium sp. ER2 Bacteria 696616284 WP_033126538.1 435 436 yes 2291929 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55601 Listonella anguillarum Bacteria UP000030318 754138269, 692109471 WP_041768981.1 640 649 yes 2291930 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 692192394 WP_032105738.1 415 417 yes 2291931 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28130, 1401075 Prevotella disiens, Prevotella disiens DNF00882 Bacteria UP000029538 739001511, 690803879 KGF48943.1 WP_036883511.1 531 531 yes 2291932 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 426 426 yes 2291933 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 39645 Mesorhizobium ciceri Bacteria 696325957 WP_032901362.1 390 404 yes 2291934 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 381 Mesorhizobium loti Bacteria UP000053176 696346353 WP_032921505.1 597 611 yes 2291935 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67827, 1114921 Citrobacter werkmanii, Citrobacter werkmanii NBRC 105721 Bacteria UP000032876 754958138, 689836501 WP_042314228.1 626 632 yes 2291936 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1538552 Clostridium sp. NCR Bacteria UP000029862 737129172, 694268318 KGJ49407.1 WP_035116677.1 437 437 yes 2291937 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 642227 Tatumella morbirosei Bacteria UP000029577 740181363, 687246540 KGD69751.1 WP_038024007.1 631 639 yes 2291938 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28132, 1401073 Prevotella melaninogenica, Prevotella melaninogenica DNF00666 Bacteria UP000029578 738980157, 690806412 KGF51087.1 WP_036863286.1 525 525 yes 2291939 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28450, 1437004, 1437003, 1434206, 1434193, 1435987, 1435049, 1439852, 1435984, 1435994 Burkholderia pseudomallei, Burkholderia pseudomallei MSHR3709, Burkholderia pseudomallei MSHR3458, Burkholderia pseudomallei MSHR4503, Burkholderia pseudomallei MSHR4032, Burkholderia pseudomallei MSHR465J, Burkholderia pseudomallei MSHR7343, Burkholderia pseudomallei K42, Burkholderia pseudomallei MSHR62, Burkholderia pseudomallei MSHR2243 Bacteria UP000029571, UP000030473, UP000030369, UP000030489, UP000030427, UP000030514, UP000030577, UP000030064, UP000030087, UP000030070 740950682, 714906706, 714676375, 714468374, 714460835, 713011723, 705557361, 701280502, 701249437, 701242361, 686962726 KGX35534.1, KGW69647.1, KGV06853.1, KGU99353.1, KGU67804.1, KGS20952.1, AIV66321.1, AIV71557.1, AIV58500.1, KGD40212.1 WP_038735503.1 642 643 yes 2291940 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 378534 Pseudomonas sp. Eur1 9.41 Bacteria 696318466 WP_032893873.1 628 629 yes 2291941 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1510041 Rhizobium sp. H41 Bacteria UP000050663 739226982, 690572440 KGE83624.1 WP_037090282.1 599 607 yes 2291942 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59924 Prochlorococcus marinus str. PAC1 Bacteria UP000030392 691698468 KGG21929.1 460 461 yes 2291943 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1229276 Sphingobacterium sp. ZW Bacteria UP000031802 739645740, 688463916 KGE13129.1 WP_037501554.1 606 606 yes 2291944 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 225117 Pyrus x bretschneideri Plants 694398172, 694398170, 694398167 XP_009374275.1, XP_009374274.1, XP_009374273.1 550 652 yes 2291945 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1492 Clostridium butyricum Bacteria UP000032253 696619674 WP_033127702.1 141 141 no 2291946 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1548018 Helicobacter sanguini Bacteria UP000029714 736557714, 693435339 KGI53303.1 WP_034570038.1 431 432 no 2291947 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 173 Leptospira interrogans Bacteria UP000037872 696580249 WP_033111435.1 193 193 no 2291948 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 696259778 WP_032837393.1 609 872 yes 2291949 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1548152 Helicobacter sp. MIT 09-6949 Bacteria UP000029733 736329226, 693736050 KGI87100.1 WP_034355967.1 452 454 yes 2291950 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1499498 Prochlorococcus sp. MIT 0601 Bacteria UP000030414 739019531, 691689934 KGG13640.1 WP_036900787.1 461 465 yes 2291951 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470 Acinetobacter baumannii Bacteria UP000028632 446452558 WP_000530413.1 358 358 yes 2291952 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219, 167551, 167550 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9401, Prochlorococcus marinus str. MIT 9322 Bacteria UP000030481, UP000030580 695319309, 691685436, 691682634 KGG09253.1, KGG06508.1 WP_032518509.1 452 456 yes 2291953 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 61647 Enterobacter gergoviae Bacteria UP000036115 759350330, 689257785 AIQ98716.1 WP_043080999.1 626 631 yes 2291954 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 42565 Halomonas salina Bacteria UP000029721 737627220, 689730728 KGE77605.1 WP_035597393.1 628 629 yes 2291955 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1487921 Clostridium sp. HMP27 Bacteria UP000030009 737326524, 695881907 KGK87731.1 WP_035309266.1 437 437 yes 2291956 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4098 Nicotiana tomentosiformis Plants 697145791 XP_009627036.1 543 646 yes 2291957 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1522 Clostridium innocuum Bacteria UP000030008 769124424, 694272325 KGJ52288.1 WP_044906503.1 435 435 yes 2291958 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1548147 Helicobacter sp. MIT 03-1614 Bacteria UP000029698 736338466, 693441756 KGI59251.1 WP_034364845.1 457 457 yes 2291959 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 64988, 1177181 Alcanivorax jadensis, Alcanivorax jadensis T9 Bacteria UP000029443 737266557, 686986878 KGD59794.1 WP_035250482.1 624 627 yes 2291960 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410618 Selenomonas sp. ND2010 Bacteria 697204152 WP_033169625.1 433 435 yes 2291961 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 470934 Pantoea vagans Bacteria UP000037628 727276677, 687250185 KGD73369.1 WP_033734850.1 631 640 yes 2291962 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1499499 Prochlorococcus sp. MIT 0602 Bacteria UP000030430 691690961 KGG14615.1 445 445 yes 2291963 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 55208 Pectobacterium wasabiae Bacteria UP000029436 696539171 WP_033072325.1 631 646 yes 2291964 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1422 Geobacillus stearothermophilus Bacteria UP000036745 696474221 WP_033013920.1 565 566 yes 2291965 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 562 Escherichia coli Bacteria UP000036210 692193332 WP_032106261.1 268 271 no 2291966 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 425400 Helicobacter sp. MIT 01-6451 Bacteria UP000029707 736334103, 693436419 KGI54338.1 WP_034360608.1 456 457 yes 2291967 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 413503 Cronobacter malonaticus Bacteria 696410306 WP_032981277.1 71 74 no 2291968 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 471858 Helicobacter magdeburgensis Bacteria UP000029921 736576974, 696169459 KGL15296.1 WP_034588326.1 463 464 yes 2291969 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 558964 Aeromonas sp. AE235 Bacteria 696632621 WP_033131529.1 650 662 yes 2291970 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1380346 Streptomycetaceae bacterium URHA0041 Bacteria 697210161 WP_033175550.1 580 581 yes 2291971 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 2226 Methanococcoides methylutens Archaea 851354413, 695945045 KGK98998.1 WP_048193430.1 A0A099T480 A0A099T480_METMT 406 415 no 2291972 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1548151 Helicobacter sp. MIT 11-5569 Bacteria UP000029923 736164192, 696164936 KGL11936.1 WP_034288546.1 442 443 yes 2291973 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 67824, 1114922 Citrobacter farmeri, Citrobacter farmeri GTC 1319 Bacteria UP000033031 754970319, 693465189 WP_042326215.1 625 633 yes 2291974 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36875 Porphyromonas canoris Bacteria UP000030101 738984965, 696213761 KGL52761.1 WP_036867568.1 590 590 yes 2291975 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 34007 Paracoccus versutus Bacteria UP000029830 738872412, 694204608 KGJ02517.1 WP_036760838.1 597 601 yes 2291976 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 135622, 1535421 Pseudoalteromonas sp. ND6B Bacteria UP000029841 696572683, 694345054 KGJ97794.1 WP_033104274.1 645 650 yes 2291977 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 413503 Cronobacter malonaticus Bacteria 696409189 WP_032980274.1 598 602 yes 2291978 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 93057 Prochlorococcus marinus str. MIT 9201 Bacteria UP000030355 691671859 KGF95983.1 424 427 yes 2291979 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33035 Blautia producta Bacteria 696669571 WP_033142903.1 434 435 yes 2291980 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 287 Pseudomonas aeruginosa Bacteria UP000065817 730234387, 686656583 KGB85209.1 WP_033939675.1 627 627 yes 2291981 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33934 Anoxybacillus flavithermus Bacteria UP000031249 692183511 WP_032099790.1 537 537 yes 2291982 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 167552 Prochlorococcus marinus str. SS2 Bacteria UP000030359 691697623 KGG21111.1 448 449 yes 2291983 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1537715 Sphingopyxis sp. MWB1 Bacteria 696541556 WP_033074517.1 620 630 yes 2291984 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 237 237 no 2291985 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1506995 Streptomyces sp. CNS654 Bacteria 695851590 WP_032764617.1 594 596 yes 2291986 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1549858 Sphingomonas taxi Bacteria UP000033203 740879511, 695171343 AIT07433.1 WP_038664759.1 607 615 yes 2291987 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1535422 Thalassotalea sp. ND16A Bacteria UP000029848 696543797, 694346748 KGJ99346.1 WP_033076723.1 649 659 yes 2291988 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 357276 Bacteroides dorei Bacteria UP000028592 696373426 WP_032948168.1 566 566 yes 2291989 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1247023 Arsenophonus endosymbiont of Nilaparvata lugens Bacteria 692295418 WP_032116429.1 621 644 yes 2291990 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 334852, 693986 Methylobacterium oryzae, Methylobacterium oryzae CBMB20 Bacteria UP000029492 760075789, 689275244 AIQ91323.1 WP_043758457.1 622 628 yes 2291991 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28229 Colwellia psychrerythraea Bacteria UP000029843 696547583, 694344688 KGJ97433.1 WP_033080319.1 647 657 yes 2291992 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 45462, 1429889 Brevibacillus borstelensis, Brevibacillus borstelensis cifa_chp40 Bacteria 686453293, 820882782 KKX54305.1 WP_031932777.1 595 598 yes 2291993 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 84111, 742768 Eggerthella lenta 1_1_60AFAA Bacteria UP000029800 737606006, 693586235 KGI71425.1 WP_035576661.1 440 441 yes 2291994 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 243924 Pseudomonas lutea Bacteria UP000029719 739151404, 691202866 KGF63861.1 WP_037015833.1 632 633 yes 2291995 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 836, 111105, 1515618 Porphyromonas gulae, Porphyromonas sp. 78870_No_COT Bacteria UP000029876, UP000029852 746384228, 806788741, 700237753, 700228595, 700220904, 696218153 KKC51309.1, KGN87048.1, KGN78281.1, KGN70782.1, KGL56977.1 WP_039427441.1 587 587 yes 2291996 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 488 Neisseria mucosa Bacteria UP000029875 738544026, 694240774 KGJ31659.1 WP_036492269.1 624 629 yes 2291997 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 696263670 WP_032841035.1 609 881 yes 2291998 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219, 167545, 167544, 59921 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9123, Prochlorococcus marinus str. MIT 9116, Prochlorococcus marinus str. MIT 9107 Bacteria UP000030513, UP000030491, UP000030370 695313315, 691670121, 691667972, 691667839 KGF94309.1, KGF92230.1, KGF92100.1 WP_032513588.1 451 456 yes 2291999 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37372 Helicobacter bilis Bacteria UP000029870 736549943, 696185100, 696183426 KGL28308.1, KGL26672.1 WP_034563068.1 452 453 yes 2292000 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1548149 Helicobacter sp. MIT 05-5293 Bacteria UP000029872 736343551, 696160657 KGL07966.1 WP_034369572.1 458 459 yes 2292001 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 447199629 WP_001276885.1 626 631 yes 2292002 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285 Comamonas testosteroni Bacteria UP000029609 736326114, 692383913, 692375582, 692368794, 692362778 KGH14972.1, KGH06812.1, KGH00152.1, KGG94318.1 WP_034352913.1 625 647 yes 2292003 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2325 Thermoanaerobacter kivui Bacteria UP000029669 694166843 AIS53014.1 428 432 yes 2292004 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 777 Coxiella burnetii Bacteria UP000033654 692118528 WP_032074850.1 542 546 yes 2292005 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 264 267 no 2292006 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 80854 Moritella viscosa Bacteria UP000032438 769993097, 692309395 WP_045108704.1 640 669 yes 2292007 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1177154 Alcanivorax sp. 19-m-6 Bacteria UP000029444 737247926, 686992373 KGD65200.1 WP_035232118.1 624 627 yes 2292008 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 549 Pantoea agglomerans Bacteria UP000050560 727302617, 687248378 KGD71572.1 WP_033759506.1 632 640 yes 2292009 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 50960 Helicobacter trogontum Bacteria UP000029861 736224985, 696192759, 696188792 KGL34448.1, KGL31387.1 WP_034317059.1 452 453 yes 2292010 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 696260285 WP_032837882.1 606 876 yes 2292011 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 214687 Musa acuminata subsp. malaccensis Plants UP000012960 695040001 XP_009407557.1 543 1261 yes 2292012 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1525715 Paracoccus sp. 4681 Bacteria 759407426, 694217653 KGJ14791.1 WP_043131769.1 598 601 yes 2292013 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 209, 76936, 1548148 Helicobacter typhlonius, Helicobacter sp. MIT 03-1616 Bacteria UP000029925, UP000029873 736243789, 696173589, 696163109 KGL18902.1, KGL10224.1 WP_034325568.1 456 457 yes 2292014 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 414996 Actinopolyspora sp. YIM 90600 Bacteria UP000029737 759889955, 693610343 KGI80167.1 WP_043576596.1 532 533 yes 2292015 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1287252 Mesorhizobium sp. LNHC252B00 Bacteria UP000020180 696332346 WP_032907654.1 596 611 yes 2292016 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1536774 Paenibacillus sp. FSL H7-0357 Bacteria UP000029508 740811495, 690619415 AIQ20628.1 WP_038596778.1 592 592 yes 2292017 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 742722 Collinsella sp. 4_8_47FAA Bacteria UP000029702 737151031, 693588496 KGI73535.1 WP_035137990.1 443 444 yes 2292018 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 696234911 WP_032814663.1 657 884 yes 2292019 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 543, 556, 158822 Erwinia chrysanthemi, Cedecea neteri Bacteria UP000030389, UP000029509 740878060, 712824199, 690287089 KGT97510.1, AIR69707.1 WP_038663308.1 631 655 yes 2292020 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 566, 1115515 Escherichia vulneris, Escherichia vulneris NBRC 102420 Bacteria UP000029462 755043083, 689826979 WP_042395581.1 588 595 yes 2292021 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28125, 1287476 Prevotella bivia, Prevotella bivia DNF00188 Bacteria UP000029616 739004780, 690775729 KGF23067.1 WP_036886523.1 523 523 yes 2292022 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1548150 Helicobacter sp. MIT 05-5294 Bacteria UP000029926 696177841 KGL21759.1 98 98 no 2292023 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 392484 Methylophaga thiooxidans Bacteria UP000029999 738362454, 697965415 KGM06128.1 WP_036314744.1 601 603 yes 2292024 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1238 Piscirickettsia salmonis Bacteria UP000065118 692315848 WP_032126870.1 216 216 no 2292025 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1386082 Cellulomonas bogoriensis 69B4 Bacteria UP000054314 697974087 KGM13846.1 547 550 yes 2292026 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 40324 Stenotrophomonas maltophilia Bacteria UP000034806 692317579, 698978524 KGM24211.1 WP_032128403.1 613 614 yes 2292027 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1410613 Prevotella sp. P6B1 Bacteria 697059286 WP_033148916.1 528 528 yes 2292028 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 632 Yersinia pestis Bacteria UP000000815 UP000031825 694148476 WP_032485421.1 442 457 yes 2292029 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1218, 1499501, 167554, 167553, 167556 Prochlorococcus sp. SS52, Prochlorococcus marinus str. SS51, Prochlorococcus marinus str. SS35, Prochlorococcus marinus str. LG Bacteria UP000030552, UP000030543, UP000030383, UP000030395 739011050, 691713216, 691708825, 691700577, 691686929 KGG36031.1, KGG31804.1, KGG23936.1, KGG10690.1 WP_036892565.1 464 466 yes 2292030 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1501269 Prochlorococcus sp. MIT 0801 Bacteria UP000029485 689271333 AIQ98226.1 447 449 yes 2292031 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 357276 Bacteroides dorei Bacteria UP000028592 696376139 WP_032950597.1 566 566 yes 2292032 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 221126 Algibacter lectus Bacteria UP000029643 693567508 418 418 no 2292033 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 221126 Algibacter lectus Bacteria UP000029643 693567507 186 186 no 2292034 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 696257159 WP_032834867.1 605 876 yes 2292035 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 285 Comamonas testosteroni Bacteria UP000029609 736354861, 692358991 KGG90594.1 WP_034380561.1 625 647 yes 2292036 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1548018 Helicobacter sanguini Bacteria UP000029714 736557278, 693437141 KGI55055.1 WP_034569625.1 96 96 no 2292037 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219, 167548 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9314 Bacteria UP000030533 695316901, 691676600 KGG00607.1 WP_032516120.1 453 456 yes 2292038 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1329516 bacterium H-18 Bacteria 696568381 WP_033100127.1 582 582 yes 2292039 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 292 Burkholderia cepacia Bacteria UP000063625 736063480, 686819368 KGB98850.1 WP_034206861.1 642 643 yes 2292040 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 32008, 28095, 13373 Burkholderia gladioli, Burkholderia mallei Bacteria UP000030188, UP000032647 516531316, 772906780, 686829814 AJW99779.1, KGC09284.1 WP_017919122.1 642 643 yes 2292041 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 339, 487899 Xanthomonas campestris, Xanthomonas campestris pv. viticola Bacteria UP000037537, UP000028862 704494946, 644957064 WP_033485051.1 624 625 yes 2292042 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1218, 1499500 Prochlorococcus sp. MIT 0603 Bacteria UP000030522 739038392, 691692338 KGG15958.1 WP_036919476.1 461 462 yes 2292043 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1502850 Sphingomonas sp. LC81 Bacteria UP000029574 739658017, 686472404 KGB55332.1 WP_037513383.1 621 630 yes 2292044 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1519190 Massilia sp. JS1662 Bacteria UP000029701 738284704, 691633864 KGF79063.1 WP_036238873.1 635 637 yes 2292045 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 59925 Prochlorococcus marinus str. GP2 Bacteria UP000030598 691661286 KGF85674.1 438 439 yes 2292046 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219, 74545 Prochlorococcus marinus, Prochlorococcus marinus str. MIT 9302 Bacteria UP000030445 695328109, 691674143 KGF98222.1 WP_032526339.1 453 456 yes 2292047 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 158822 Cedecea neteri Bacteria UP000029509 740691479, 725660641, 689264641 KHE37974.1, AIR05171.1 WP_038476768.1 626 633 yes 2292048 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1491 Clostridium botulinum Bacteria UP000030128 696531074 WP_033064562.1 368 368 no 2292049 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28901, 1386967 Salmonella enterica, Salmonella enterica subsp. arizonae serovar 62:z36:- str. RKS2983 Bacteria UP000054489, UP000029400 740611706, 686509977 AIP96268.1 WP_038397226.1 626 631 yes 2292050 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2226 Methanococcoides methylutens Archaea 851358676, 695944349 KGK98307.1 WP_048195690.1 A0A099SZI8 A0A099SZI8_METMT 427 427 yes 2292051 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1219 Prochlorococcus marinus Bacteria 695324457 WP_032522761.1 125 126 no 2292052 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1548150 Helicobacter sp. MIT 05-5294 Bacteria UP000029926 696194126 KGL35304.1 409 409 yes 2292053 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 190047 Prochlorococcus marinus str. EQPAC1 Bacteria UP000030596 691662479 KGF86859.1 437 439 yes 2292054 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 696260768 WP_032838347.1 608 872 yes 2292055 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219626 Peptostreptococcus sp. MV1 Bacteria UP000029560 738874915, 690766171 KGF14186.1 WP_036762990.1 434 434 yes 2292056 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1501268 Prochlorococcus sp. MIT 0604 Bacteria UP000029517 757603699, 689268915 AIQ95976.1 WP_042851143.1 453 456 yes 2292057 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1238 Piscirickettsia salmonis Bacteria UP000065118 692316060 WP_032126984.1 623 625 yes 2292058 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29495 Vibrio navarrensis Bacteria UP000029860 746398155, 694878336 KGK22213.1 WP_039440454.1 639 645 yes 2292059 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 44251 Paenibacillus durus Bacteria UP000029409 686569078 AIQ13134.1 583 584 yes 2292060 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1532558 Rhizobium sp. YS-1r Bacteria UP000029602 739291639, 687290587 KGD95761.1 WP_037154333.1 599 603 yes 2292061 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 335 335 yes 2292062 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 134034, 1287475 Corynebacterium freneyi, Corynebacterium freneyi DNF00450 Bacteria UP000029548 737134137, 690769709 KGF17449.1 WP_035121487.1 559 562 yes 2292063 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1532557 Achromobacter sp. RTa Bacteria UP000035841 759855707, 687285487 KGD90745.1 WP_043546842.1 636 637 yes 2292064 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2226 Methanococcoides methylutens Archaea 851357108, 695943795 KGK97753.1 WP_048194792.1 A0A099T0X1 A0A099T0X1_METMT 432 432 yes 2292065 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 37332 Nocardia seriolae Bacteria UP000037179 696554057, 749292509 WP_033086252.1 550 553 yes 2292066 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28125, 1401068 Prevotella bivia, Prevotella bivia DNF00320 Bacteria UP000029525 738983784, 690799525 KGF45089.1 WP_036866474.1 523 523 yes 2292067 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 190893 Vibrio coralliilyticus Bacteria UP000033403 740729001, 700288375 AIU68275.1 WP_038514287.1 640 646 yes 2292068 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 169760 Paenibacillus stellifer Bacteria UP000029507 740915735, 686553549 AIQ64244.1 WP_038700982.1 583 583 yes 2292069 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 669 Vibrio harveyi Bacteria UP000067422 696462250 WP_033006980.1 640 646 yes 2292070 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 157783 Pseudomonas cremoricolorata Bacteria UP000029493 740625541, 691225047 AIR88331.1 WP_038411053.1 627 628 yes 2292071 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2702 Gardnerella vaginalis Bacteria UP000037770 696264641 WP_032841803.1 613 876 yes 2292072 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 204516 Bacteroides massiliensis Bacteria 696367027 WP_032942039.1 566 566 yes 2292073 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28095 Burkholderia gladioli Bacteria UP000030188 738071214, 687991769 KGE11493.1 WP_036030090.1 642 643 yes 2292074 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1219, 59926 Prochlorococcus marinus, Prochlorococcus marinus str. SB Bacteria UP000030345 695321673, 691684853 KGG08673.1 WP_032519997.1 453 456 yes 2292075 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 135569 Helicobacter apodemus Bacteria UP000029920 736539837, 696171520 KGL17019.1 WP_034554499.1 421 421 no 2333070 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 561440, 1384057 Bacillus sp. BLB-1, Lysinibacillus sinduriensis BLB-1 = JCM 15800 Bacteria UP000030408 738243328, 704820460 KGR76968.1 WP_036198566.1 593 594 yes 2333071 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1883 702723332 WP_033247896.1 588 609 yes 2333072 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111105 Porphyromonas gulae Bacteria UP000029876 746378911, 700233895 KGN83401.1 WP_039422578.1 587 587 yes 2333073 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1536652 Desulfobulbus sp. Tol-SR Bacteria UP000030148 737244616, 700404399 KGO34559.1 WP_035228853.1 428 428 yes 2333074 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53329 Desulfospira joergensenii Bacteria 703308330 WP_033398405.1 424 424 yes 2333075 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 172045 Elizabethkingia miricola Bacteria UP000030102 736870097, 700268297 KGO10207.1 WP_034869784.1 602 602 yes 2333076 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111105 Porphyromonas gulae Bacteria UP000029876 746396702, 700259843 KGO01959.1 WP_039439073.1 587 587 yes 2333077 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 309788, 1294264 Lysinibacillus boronitolerans, Lysinibacillus boronitolerans JCM 21713 = 10a = NBRC 103108 Bacteria UP000030487 738117896, 704832015 KGR88260.1 WP_036075969.1 592 592 yes 2333078 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 208444 Amycolatopsis vancoresmycina Bacteria 702776404 WP_033261591.1 543 545 yes 2333079 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78343 Bifidobacterium boum Bacteria UP000029093 705387717 WP_033489946.1 571 862 yes 2333080 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 218140 Bifidobacterium psychraerophilum Bacteria UP000029050 705403648 WP_033498253.1 605 621 yes 2333081 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1515617 Porphyromonas sp. 78862_COT.290 Bacteria UP000030105 763375844, 700248621 KGN97631.1 WP_044233036.1 594 596 yes 2333082 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 77635 Bifidobacterium subtile Bacteria UP000029055 705417903 WP_033502989.1 575 856 yes 2333083 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 657326, 1406840 Flavobacterium sp. F44-8, Flavobacterium beibuense F44-8 Bacteria UP000030129 737147101, 700532717 KGO80262.1 WP_035134262.1 606 606 yes 2333084 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33905 Bifidobacterium thermophilum Bacteria UP000029019 705394767 WP_033493330.1 572 862 yes 2333085 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111105 Porphyromonas gulae Bacteria UP000029876 746402933, 700227061 KGN76804.1 WP_039444836.1 587 587 yes 2333086 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33876 Catenuloplanes japonicus Bacteria 703072131 WP_033342836.1 528 530 yes 2333087 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2065 Kitasatospora phosalacinea Bacteria 702746676 WP_033253470.1 599 606 yes 2333088 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 43759 Streptomyces wedmorensis Bacteria 702559018 WP_033201423.1 592 594 yes 2333089 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2065 Kitasatospora phosalacinea Bacteria 702601792 WP_033217767.1 599 605 yes 2333090 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1505907 Thermococcus sp. A501 Archaea UP000029980 700303729 AIU70548.1 A0A097QVQ1 A0A097QVQ1_9EURY 426 426 yes 2333091 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1517682 Porphyromonadaceae bacterium COT-184 Bacteria UP000030107 738944938, 700228124 KGN77835.1 WP_036829901.1 587 587 yes 2333092 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 346181, 1385517 Lysobacter daejeonensis, Lysobacter daejeonensis GH1-9 Bacteria UP000029998 738180007, 699267358 KGM54771.1 WP_036136638.1 624 625 yes 2333093 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 266762 Porphyromonas gingivicanis Bacteria UP000030134 739001403, 700248939 KGN97941.1 WP_036883405.1 589 589 yes 2333094 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550 Enterobacter cloacae Bacteria UP000036177 740632926, 701193256 AIV27891.1 WP_038418431.1 626 631 yes 2333095 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 68219 Streptomyces iakyrus Bacteria 702917985 WP_033309862.1 592 594 yes 2333096 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463861 Streptomyces sp. NRRL F-525 Bacteria 702854953 WP_033285773.1 594 606 yes 2333097 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28450, 1437000 Burkholderia pseudomallei, Burkholderia pseudomallei MSHR1153 Bacteria UP000029571, UP000030067 759554930, 701235148 AIV51295.1 WP_043274719.1 642 643 yes 2333098 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1542, 1444290 Clostridium novyi, Clostridium novyi A str. 4570 Bacteria UP000030016 746191374, 699763459 KGN02495.1 WP_039249536.1 437 437 yes 2333099 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 271420 Pseudomonas xanthomarina Bacteria UP000039940 751307568, 703403327 WP_041015871.1 626 626 yes 2333100 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1537504 Porphyromonas sp. COT-108_OH1349 Bacteria UP000030126 738964306, 700217862 KGN67798.1 WP_036848166.1 590 590 yes 2333101 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 78398 Pectobacterium carotovorum subsp. odoriferum Bacteria UP000029439 700311807 AIU86927.1 631 659 yes 2333102 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550 Enterobacter cloacae Bacteria UP000036177 704516880 WP_033487987.1 626 631 yes 2333103 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28450, 1434929 Burkholderia pseudomallei, Burkholderia pseudomallei ABCPW 111 Bacteria UP000029571 740960203, 705476146 KGS05943.1 WP_038744790.1 642 643 yes 2333104 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 414050, 1300345 Thermomonas dokdonensis, Lysobacter dokdonensis DS-58 Bacteria UP000030518 738215069, 702085912 KGQ18274.1 WP_036170721.1 621 625 yes 2333105 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 304899 Actinospica acidiphila Bacteria 702816177 WP_033273287.1 595 598 yes 2333106 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1385522, 913325 Lysobacter arseniciresistens, Lysobacter sp. ZS79 Bacteria UP000029989 738257326, 699267046 KGM54464.1 WP_036212405.1 622 625 yes 2333107 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 65058, 1006579 Corynebacterium ulcerans, Corynebacterium ulcerans FRC11 Bacteria UP000029905, UP000029910 740835347, 698973159 AIU32969.1 WP_038620630.1 558 569 yes 2333108 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1385520 Knoellia sinensis KCTC 19936 Bacteria UP000030002 700170632 KGN31630.1 576 583 yes 2333109 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2030 Kibdelosporangium aridum Bacteria 703240495 WP_033390999.1 543 544 yes 2333110 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 518643 Bifidobacterium mongoliense Bacteria 705439027 WP_033513258.1 635 861 yes 2333111 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2066 Kitasatospora setae Bacteria 702760765 WP_033257699.1 595 597 yes 2333112 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 505317 Chelonobacter oris Bacteria UP000030380 736603563, 703885618 KGQ71391.1 WP_034612251.1 628 641 yes 2333113 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 246618 Bifidobacterium thermacidophilum Bacteria 705422892 WP_033505128.1 572 870 yes 2333114 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 84025, 1443115 Clostridium haemolyticum, Clostridium haemolyticum NCTC 8350 Bacteria UP000030007 746187743, 699765775 KGN04667.1 WP_039246190.1 203 207 no 2333115 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1515613 Porphyromonas sp. 54552_COT.239 Bacteria UP000030150 738999194, 700219753 KGN69652.1 WP_036881286.1 591 592 yes 2333116 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 588672 Patulibacter americanus Bacteria 702575502 WP_033206857.1 436 439 yes 2333117 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1538295 Aquabacterium sp. NJ1 Bacteria UP000029993 737046501, 699056227 KGM42019.1 WP_035041711.1 621 633 yes 2333118 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 758828 Succinivibrionaceae bacterium WG-1 Bacteria 703625738 WP_033445977.1 352 354 no 2333119 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 171674, 1398085 Inquilinus limosus, Inquilinus limosus MP06 Bacteria UP000029995 736831969, 699015537 KGM35058.1 WP_034833348.1 600 601 yes 2333120 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1547444 Pseudoalteromonas sp. PLSV Bacteria 700668823 WP_033185618.1 621 628 yes 2333121 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2423 Fervidobacterium islandicum Bacteria 701167389, 728897103 KHG32522.1 WP_033192404.1 431 432 yes 2333122 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 51367 Salinivibrio costicola Bacteria 703203966 WP_033379128.1 640 640 yes 2333123 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 103733 Saccharothrix syringae Bacteria 703479448 WP_033432243.1 547 549 yes 2333124 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 56459 Xanthomonas vasicola Bacteria UP000030936 746391670, 704128404, 704114978, 704109759, 704108555 KGR61545.1, KGR49494.1, KGR44757.1, KGR43631.1 WP_039434404.1 624 625 yes 2333125 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2371 Xylella fastidiosa Bacteria UP000028529 740398327, 698632289 KGM21102.1 WP_038232007.1 594 601 yes 2333126 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66378 Streptomyces yerevanensis Bacteria 702998131 WP_033321267.1 597 606 yes 2333127 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28450, 1435371 Burkholderia pseudomallei, Burkholderia pseudomallei MSHR7527 Bacteria UP000029571, UP000030558 740991753, 705639144 KGS64676.1 WP_038775014.1 642 643 yes 2333128 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1461694 Oceanicola sp. 22II-S11g Bacteria UP000030004 760071197, 699258628 KGM46917.1 WP_043754005.1 601 604 yes 2333129 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 198467 Anoxybacillus gonensis Bacteria UP000065017 737071375, 701227500 KGP60776.1 WP_035065668.1 560 561 yes 2333130 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 150396 Pseudomonas sp. MT-1 Bacteria UP000031648 779982492, 699965624 WP_045423977.1 626 626 yes 2333131 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111105 Porphyromonas gulae Bacteria UP000029876 746391476, 700261865, 700225938 KGO03931.1, KGN75698.1 WP_039434214.1 587 587 yes 2333132 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 262325, 1122185 Lysobacter concretionis, Lysobacter concretionis Ko07 = DSM 16239 Bacteria UP000030017 738240413, 699263357 KGM50903.1 WP_036195710.1 623 625 yes 2333133 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28450, 1439856, 1439857, 1439854, 1439855 Burkholderia pseudomallei, Burkholderia pseudomallei A79C, Burkholderia pseudomallei A79D, Burkholderia pseudomallei B03, Burkholderia pseudomallei A79A Bacteria UP000029571, UP000030387, UP000030459, UP000030080, UP000030068 740976429, 718033989, 718032394, 701269007, 701260674 KGY01424.1, KGX99873.1, AIV91691.1, AIV95274.1 WP_038760573.1 642 643 yes 2333134 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 47763 Streptomyces lydicus Bacteria 702795770 WP_033267047.1 593 597 yes 2333135 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1542, 1444289 Clostridium novyi, Clostridium novyi A str. 4552 Bacteria UP000030012 746194526, 699758710 KGM97947.1 WP_039252590.1 437 437 yes 2333136 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 35754 Dactylosporangium aurantiacum Bacteria 703137939 WP_033356572.1 511 512 yes 2333137 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1772, 246196 Mycobacterium smegmatis, Mycobacterium smegmatis str. MC2 155 Bacteria UP000029911, UP000029906 738514086, 698956800, 698948517, 698939324 AIU19335.1, AIU12711.1, AIU06086.1 WP_036462589.1 529 532 yes 2333138 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 36874 Porphyromonas cangingivalis Bacteria UP000029825 738967084, 700232866 KGN82403.1 WP_036850907.1 596 597 yes 2333139 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28115 Porphyromonas macacae Bacteria UP000030100 738992458, 700223507 KGN73325.1 WP_036874688.1 591 591 yes 2333140 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 184882, 1385521 Knoellia subterranea, Knoellia subterranea KCTC 19937 Bacteria UP000030011 737941063, 700176369 KGN37213.1 WP_035905422.1 576 589 yes 2333141 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 948 Anaplasma phagocytophilum Bacteria UP000033356 701521780 528 528 yes 2333142 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 680 Vibrio campbellii Bacteria UP000030534 835382372, 704007947 KGR32686.1 WP_047482804.1 640 646 yes 2333143 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28115 Porphyromonas macacae Bacteria UP000030100 738968717, 700250499 KGN99475.1 WP_036852489.1 591 591 yes 2333144 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1478 Bacillus simplex Bacteria UP000064189 701524267 593 593 yes 2333145 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111105 Porphyromonas gulae Bacteria UP000029876 746382570, 700236311 KGN85695.1 WP_039425988.1 587 587 yes 2333146 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 276 Thermus filiformis Bacteria UP000030364 740218816, 702225298 KGQ22974.1 WP_038060634.1 431 434 yes 2333147 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1829 Rhodococcus rhodochrous Bacteria 702666965 WP_033235799.1 506 506 yes 2333148 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29488 Photorhabdus luminescens Bacteria UP000029997 738928042, 699001221 KGM25923.1 WP_036814777.1 619 645 yes 2333149 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1760 702715851 WP_033246375.1 540 542 yes 2333150 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 305900 Endozoicomonas elysicola Bacteria UP000027997 703350300 WP_033402846.1 563 564 yes 2333151 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 330084 Amycolatopsis jejuensis Bacteria 702881009 WP_033294471.1 544 547 yes 2333152 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 339, 487849 Xanthomonas campestris, Xanthomonas campestris pv. arecae Bacteria UP000037537, UP000030131 835905301, 701220360 KGP55729.1 WP_047700189.1 624 625 yes 2333153 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 346, 434928 Xanthomonas citri, Xanthomonas citri pv. citri Bacteria UP000052252 749640950, 703423893 WP_040242677.1 624 625 yes 2333154 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 238 Elizabethkingia meningoseptica Bacteria UP000064940 706026522 KGT08936.1 602 602 yes 2333155 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 836, 1515614, 36875 Porphyromonas sp. 54572_COT.108, Porphyromonas canoris Bacteria UP000030113, UP000030101 738905703, 700246593, 700242576 KGN95668.1, KGN91743.1 WP_036792639.1 590 590 yes 2333156 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4096 Nicotiana sylvestris Plants 698563209 XP_009772632.1 545 646 yes 2333157 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1536651 Desulfosporosinus sp. Tol-M Bacteria UP000030439 736607772, 701595067 KGP75235.1 WP_034616316.1 425 425 yes 2333158 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816 Bifidobacterium longum Bacteria UP000028505 705420546 WP_033504129.1 635 917 yes 2333159 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66869 Streptomyces atroolivaceus Bacteria 702889162 WP_033296803.1 598 612 yes 2333160 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1961 Streptomyces virginiae Bacteria UP000037084 702595551 WP_033215007.1 592 595 yes 2333161 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 630129 Bifidobacterium kashiwanohense Bacteria 705412459 WP_033501246.1 603 871 yes 2333162 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 96230, 1212491 Legionella fallonii, Legionella fallonii LLAP-10 Bacteria UP000032430 769980765, 698844467 WP_045096750.1 556 557 yes 2333163 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1894 Streptomyces aureofaciens Bacteria UP000037395 703102330 WP_033348303.1 602 604 yes 2333164 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1463825 Saccharothrix sp. NRRL B-16314 Bacteria 703489984 WP_033442577.1 547 549 yes 2333165 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1515615 Porphyromonas sp. 54627_COT.290 Bacteria UP000030116 763330250, 700234836 KGN84299.1 WP_044188647.1 594 596 yes 2333166 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 447106 Leptospira licerasiae Bacteria 702813195 WP_033272290.1 505 505 yes 2333167 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 595 608 yes 2345094 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 159450 Burkholderia sacchari Bacteria UP000030460 737558341, 723581965 KHD19206.1 WP_035530977.1 642 643 yes 2345095 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 53413, 317013 Xanthomonas axonopodis, Xanthomonas axonopodis pv. phaseoli Bacteria UP000054035, UP000030394 746540322, 740570272, 740569605, 740558015, 740552983, 724708280, 724703855, 724698488, 712569414 KHS41514.1, KHS40864.1, KHS29816.1, KHS24932.1, KHD70551.1, KHD67140.1, KHD62075.1, KGT51882.1 WP_039572667.1 624 625 yes 2345096 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 487 Neisseria meningitidis Bacteria UP000050419 757464422, 726974781 KHF22220.1 WP_042745201.1 625 633 yes 2345097 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4432 Nelumbo nucifera Plants 720021605 XP_010262777.1 547 647 yes 2345098 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 111527, 1439860, 1435988 Burkholderia pseudomallei TSV28, Burkholderia sp. MSHR44 Bacteria UP000030592 740953722, 715024878, 714841688 KGX65918.1, KGX08512.1 WP_038738360.1 642 643 yes 2345099 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1548750 Anoxybacillus sp. BCO1 Bacteria UP000030702 727073481 KHF27962.1 338 356 no 2345100 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1548750 Anoxybacillus sp. BCO1 Bacteria UP000030702 727073482 KHF27963.1 207 211 no 2345101 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29581 Janthinobacterium lividum Bacteria UP000023814 736782269, 722540996 KHA77056.1 WP_034784795.1 636 637 yes 2345102 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 723044905 WP_033545276.1 626 631 yes 2345103 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1242993 Ehrlichia sp. UFMG-EV Bacteria UP000038403 771517498, 726990596 WP_045170635.1 554 554 yes 2345104 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 237368 Candidatus Scalindua brodae Bacteria UP000030652 726045683 KHE92544.1 422 447 yes 2345105 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 584 Proteus mirabilis Bacteria UP000033762 739014353, 721504445 KGY47937.1 WP_036895735.1 620 650 yes 2345106 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28213, 1219049 Sphingomonas parapaucimobilis, Sphingomonas parapaucimobilis NBRC 15100 Bacteria UP000032305 755134989, 723386115 WP_042485191.1 607 622 yes 2345107 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615 Serratia marcescens Bacteria UP000055021 835589369, 721591657 KGZ34928.1 WP_047573071.1 632 647 yes 2345108 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 66269 Pantoea stewartii Bacteria UP000030462 746296137, 734493443, 725506772 KHN59134.1, KHD99267.1 WP_039343278.1 632 640 yes 2345109 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 546 Citrobacter freundii Bacteria UP000030582 835229781, 721586376 KGZ29650.1 WP_047407338.1 626 632 yes 2345110 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 645, 29491 Aeromonas salmonicida, Aeromonas salmonicida subsp. salmonicida Bacteria UP000052231, UP000032527 759420096, 726079393 KHE98959.1 WP_043143931.1 644 661 yes 2345111 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550 Enterobacter cloacae Bacteria UP000036177 779797367, 829456283, 829445118, 829410769, 829279331, 771441635, 770950756, 721546693 KLR46839.1, KLR35760.1, KLR02027.1, KLP75885.1, KJP72350.1, KJL51164.1, KGY90033.1 WP_045328864.1 626 631 yes 2345112 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 279058 Collimonas arenae Bacteria UP000030302 740700265, 725876200 AIY39946.1 WP_038485554.1 636 637 yes 2345113 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 333138 Bacillus okhensis Bacteria UP000030832 736625964, 727087529 KHF37850.1 WP_034634046.1 593 594 yes 2345114 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1347370 Pantoea sp. FF5 Bacteria 727338773 WP_033793162.1 631 641 yes 2345115 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2045 Pimelobacter simplex Bacteria UP000030300 740892043, 723623008 AIY16484.1 WP_038677291.1 554 554 yes 2345116 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 752546292, 725522116 KHE14366.1 WP_041217674.1 645 663 yes 2345117 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1550091 Sphingobacteriaceae bacterium DW12 Bacteria 723442978 WP_033564532.1 606 606 yes 2345118 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1003181 Candidatus Thiomargarita nelsonii Bacteria UP000030428 723293709, 723289731 KHD12456.1, KHD09643.1 281 281 no 2345119 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 33898 Streptomyces galbus Bacteria 716922089 WP_033530688.1 594 608 yes 2345120 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1469502 Burkholderiales bacterium GJ-E10 Bacteria UP000031649 780089738, 723003289 WP_045467682.1 612 620 yes 2345121 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1231241 Thermotoga sp. Mc24 Bacteria UP000030509 740212288, 723259300 KHC90765.1 WP_038054150.1 424 424 yes 2345122 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 562 Escherichia coli Bacteria UP000036210 723051965 WP_033548572.1 626 631 yes 2345123 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 615 Serratia marcescens Bacteria UP000055021 835582165, 721568963 KGZ12265.1 WP_047569731.1 632 647 yes 2345124 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1396 Bacillus cereus Bacteria UP000036076 446737207 WP_000814463.1 498 498 no 2345125 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1577887 Dickeya sp. 2B12 Bacteria 723589518 WP_033568015.1 631 655 yes 2345126 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 701175 Vibrio sp. N384 Bacteria UP000030421 740302428, 723629865 KHD24200.1 WP_038139841.1 640 646 yes 2345127 uncharacterized Radical SAM Phosphomethylpyrimidine Synthase extended sequence 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1003181 Candidatus Thiomargarita nelsonii Bacteria UP000030428 723293561, 723289514 KHD12359.1, KHD09498.1 341 342 no 2345128 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1392 Bacillus anthracis Bacteria UP000034470 835253557, 721827328 KGZ87238.1 WP_047421055.1 586 586 yes 2345129 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 371042 Pantoea sp. Y1 Bacteria UP000030351 736899634, 712782223 KGT87149.1 WP_034898561.1 632 644 yes 2345130 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1484157 Pantoea sp. PSNIH2 Bacteria UP000030310 740844547, 723243086 AIX75722.1 WP_038629800.1 630 640 yes 2345131 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1526743 Pantoea sp. NGS-ED-1003 Bacteria 727298597 WP_033755837.1 631 641 yes 2345132 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644 Aeromonas hydrophila Bacteria UP000032249 759446898, 722064510 KHA54395.1 WP_043168738.1 645 663 yes 2345133 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28450, 1434197, 1434196 Burkholderia pseudomallei, Burkholderia pseudomallei MSHR4308, Burkholderia pseudomallei MSHR4304 Bacteria UP000029571, UP000030485, UP000030426 752547470, 714503879, 713015479 KGV34555.1, KGU71530.1 WP_041218724.1 642 643 yes 2345134 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 628 Xenorhabdus nematophila Bacteria UP000031446 740385470, 724088134 KHD28118.1 WP_038220077.1 625 650 yes 2345135 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1763 740777872 WP_038563156.1 541 542 yes 2345136 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 645, 29491 Aeromonas salmonicida, Aeromonas salmonicida subsp. salmonicida Bacteria UP000052231, UP000032527 759426100, 760177725, 726081130 KIX25784.1, KHF00642.1 WP_043149470.1 644 661 yes 2345137 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 545 Citrobacter koseri Bacteria UP000053089 835333380, 721474584 KGY18172.1 WP_047459745.1 626 631 yes 2345138 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1488 Clostridium acetobutylicum Bacteria UP000030591 736572834, 724475903 KHD35787.1 WP_034584445.1 436 436 yes 2345139 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1484158 Pantoea sp. PSNIH1 Bacteria UP000030307 746336382, 723255919 AIX49940.1 WP_039381840.1 634 644 yes 2345140 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 29498 Vibrio tubiashii Bacteria UP000030463 740374803, 719404160 KGY10971.1 WP_038210067.1 640 646 yes 2345141 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 727200094 WP_033661654.1 530 530 yes 2345142 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1538553 Methylomonas sp. FJG1 Bacteria UP000030512 738319840, 724406535 KHD33094.1 WP_036272826.1 621 622 yes 2345143 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28450, 1437002 Burkholderia pseudomallei, Burkholderia pseudomallei MSHR3335 Bacteria UP000029571, UP000030488 752523512, 714908226 KGX37048.1 WP_041195097.1 642 643 yes 2345144 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 183795, 1348058 Pseudomonas mediterranea, Pseudomonas mediterranea CFBP 5447 Bacteria UP000030194 835905781, 713118228 KGU85662.1 WP_047700401.1 628 629 yes 2345145 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1869 Actinoplanes utahensis Bacteria UP000054537 759835400, 724741411 KHD73742.1 WP_043531041.1 510 522 yes 2345146 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 216816, 1679 Bifidobacterium longum, Bifidobacterium longum subsp. longum Bacteria UP000028505, UP000029007 835177166, 725285218 KHD94174.1 WP_047379911.1 635 917 yes 2345147 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 379097 Vibrio sinaloensis Bacteria UP000031444 740356181, 719379691 KGY07386.1 WP_038192450.1 640 646 yes 2345148 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 648 Aeromonas punctata Bacteria UP000054115 752542884, 721527775 KGY71160.1 WP_041214324.1 645 663 yes 2345149 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 2340 Solemya velum gill symbiont Bacteria UP000030856 759393320, 727068109 KHF24121.1 WP_043118166.1 627 630 yes 2345150 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 4432 Nelumbo nucifera Plants 720002311 XP_010256639.1 469 649 yes 2345151 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28450, 1435989 Burkholderia pseudomallei, Burkholderia pseudomallei MSHR983 Bacteria UP000029571, UP000030404 741006032, 713008885 KGU64969.1 WP_038788506.1 642 643 yes 2345152 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1565129 Shewanella sp. ECSMB14101 Bacteria 719261591 WP_033538087.1 646 653 yes 2345153 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 556 Erwinia chrysanthemi Bacteria UP000030389 723598276 WP_033575470.1 631 655 yes 2345154 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 354276, 61645, 550 Enterobacter asburiae, Enterobacter cloacae Bacteria UP000036088, UP000036177 779957394, 829267170, 822849151, 772475233, 771210268, 721521897 KLP65867.1, KLG07027.1, KJQ03790.1, KJN52096.1, KGY65302.1 WP_045404844.1 626 631 yes 2345155 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1509403 Acinetobacter sp. HR7 Bacteria UP000032870 736576145, 712286005 KGT46763.1 WP_034587545.1 627 632 yes 2345156 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 990271 Vibrio variabilis Bacteria UP000030520 740382917, 722081932 KHA58872.1 WP_038217675.1 640 646 yes 2345157 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28450, 1434200 Burkholderia pseudomallei, Burkholderia pseudomallei MSHR4377 Bacteria UP000029571, UP000030510 740997700, 714455041 KGU93562.1 WP_038780558.1 642 643 yes 2345158 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1423 Bacillus subtilis Bacteria UP000030083 740643203, 721328637 AIX06636.1 WP_038428653.1 590 590 yes 2345159 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 57706 Citrobacter braakii Bacteria UP000030516 835411318, 725515708 KHE08088.1 WP_047498840.1 626 632 yes 2345160 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 648 Aeromonas punctata Bacteria UP000054115 721525606 KGY69008.1 645 663 yes 2345161 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 237368 Candidatus Scalindua brodae Bacteria UP000030652 726045655 KHE92519.1 427 427 yes 2345162 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396 Bacillus cereus Bacteria UP000036076 446737215 WP_000814471.1 586 586 yes 2345163 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1396 Bacillus cereus Bacteria UP000036076 446737216 WP_000814472.1 586 586 yes 2345164 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 984195 Pseudomonas sp. SHC52 Bacteria UP000031550 751315923, 727045753 WP_041022686.1 628 629 yes 2345165 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 57706 Citrobacter braakii Bacteria UP000030516 835244482, 725518468 KHE10847.1 WP_047415994.1 626 632 yes 2345166 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 421058, 1300143 Chryseobacterium oranimense, Chryseobacterium oranimense G311 Bacteria UP000043556 751290654, 724417992 WP_040999313.1 603 603 yes 2345167 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 28450, 1434201 Burkholderia pseudomallei, Burkholderia pseudomallei MSHR4299 Bacteria UP000029571, UP000030503 752525566, 714545686 KGV76222.1 WP_041197139.1 642 643 yes 2345168 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 727206152 WP_033667612.1 530 530 yes 2345169 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1852 Saccharomonospora viridis Bacteria UP000030848 727122935 KHF44214.1 547 551 yes 2345170 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 550 Enterobacter cloacae Bacteria UP000036177 835735773, 721565567 KGZ08890.1 WP_047637925.1 626 631 yes 2345171 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 412384 Bacillus aryabhattai Bacteria UP000036495 723603968 WP_033580868.1 589 589 yes 2345172 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 644, 648 Aeromonas hydrophila, Aeromonas punctata Bacteria UP000032249, UP000054115 757620719, 721534652 KGY78011.1 WP_042864551.1 645 663 yes 2345173 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 351187 Salinispora pacifica Bacteria 727321065 WP_033776327.1 530 530 yes 2345174 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 69218 Enterobacter cancerogenus Bacteria UP000030397 736827361, 712783223 KGT88105.1 WP_034828913.1 631 641 yes 2345175 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1126, 449439 Microcystis aeruginosa, Microcystis aeruginosa NIES-44 Bacteria UP000030321 779881149, 718247870 WP_045361337.1 457 460 yes 2345176 phosphomethylpyrimidine synthase (ThiC) 113 Radical SAM Phosphomethylpyrimidine Synthase IEA 1114 phosphomethylpyrimidine synthase (ThiC) 407 phosphomethylpyrimidine synthase (ThiC) IEA 1003181 Candidatus Thiomargarita nelsonii Bacteria UP000030428 723283895 KHD05194.1 620 621 yes